|
Name |
Accession |
Description |
Interval |
E-value |
| COG5028 |
COG5028 |
Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking ... |
273-1076 |
1.39e-176 |
|
Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion];
Pssm-ID: 227361 [Multi-domain] Cd Length: 861 Bit Score: 538.99 E-value: 1.39e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 273 AVSGLPYGPPSAQVAPPLGFPGQMQPPRYGMGPLPNQSMTNIP---TAMGQPGATVPGPSRIDP---------------- 333
Cdd:COG5028 18 TGAASSKKSARPHRAYANFSAGQMGMPPYTTPPLQQQSRRQIDqaaTAMHNTGANNPAPSVMSPafqsqqkfsspyggsm 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 334 --NQIPRPGSSSSPTVFETRQ----SNQANPP----PPATSDYVVRDTGNCSPRYMRCTINQIPCTVDLLSTSGMQLALM 403
Cdd:COG5028 98 adGTAPKPTNPLVPVDLFEDQpppiSDLFLPPppivPPLTTNFVGSEQSNCSPKYVRSTMYAIPETNDLLKKSKIPFGLV 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 404 VQPLALSHPSEEPIQVVDfgEGGPVRCSRCKGYINPFMKFIDQGRKFICNFCGYTDETPRDYHCNLGPDGRRRDVDERPE 483
Cdd:COG5028 178 IRPFLELYPEEDPVPLVE--DGSIVRCRRCRSYINPFVQFIEQGRKWRCNICRSKNDVPEGFDNPSGPNDPRSDRYSRPE 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 484 LCRGTVEFVATKEYMVRDPMPAVYFFLIDVSMNAIQTGATAAACNAIQQVLSDLPE-GPRTFVGIATFDSTIHFYNLKRA 562
Cdd:COG5028 256 LKSGVVDFLAPKEYSLRQPPPPVYVFLIDVSFEAIKNGLVKAAIRAILENLDQIPNfDPRTKIAIICFDSSLHFFKLSPD 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 563 LQQPlMLIVPDVQDVYTPLET-DVVVQLSECRQHLELLLDSIPTMFQESKIPESAFGAAVKAAFLAMKSKGGKLMVFQSI 641
Cdd:COG5028 336 LDEQ-MLIVSDLDEPFLPFPSgLFVLPLKSCKQIIETLLDRVPRIFQDNKSPKNALGPALKAAKSLIGGTGGKIIVFLST 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 642 LCSVGVGALSSReaegranmsagEKEAHKLLQPADKTLKTMAIEFAEYQVCVDIFITTQAYVDMASISVIPRTTGGQVYC 721
Cdd:COG5028 415 LPNMGIGKLQLR-----------EDKESSLLSCKDSFYKEFAIECSKVGISVDLFLTSEDYIDVATLSHLCRYTGGQTYF 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 722 YYPFSA--LSDPPKLYNDLKWNITRPQGFEAVMRVRCSQGIQVQEYSGNFCKRIPTDIDLPA------------HDDKLQ 787
Cdd:COG5028 484 YPNFSAtrPNDATKLANDLVSHLSMEIGYEAVMRVRCSTGLRVSSFYGNFFNRSSDLCAFSTmprdtsllvefsIDEKLM 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 788 dGAECAFQCALLYTTIYGERRIRVTTLSLSCTNMLSNLFRAADLDSQFACMLKQAANEIPSKALPLVKEQATNSCINALY 867
Cdd:COG5028 564 -TSDVYFQVALLYTLNDGERRIRVVNLSLPTSSSIREVYASADQLAIACILAKKASTKALNSSLKEARVLINKSMVDILK 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 868 AYRKFCATVTSSGQLILPEALKLFPLYTLALTKSVGLRTDG-RIDDRSFWINYVSSLSTPLAIPLVYPRMISVHDL---- 942
Cdd:COG5028 643 AYKKELVKSNTSTQLPLPANLKLLPLLMLALLKSSAFRSGStPSDIRISALNRLTSLPLKQLMRNIYPTLYALHDMpiea 722
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 943 DVKDTEGSVLPPPIPLSSEHISNEGVYFLENGEDGLLFVGESVDSDILQKLFAVSSAAEIPN-QFVLQQYDNQLSKKFND 1021
Cdd:COG5028 723 GLPDEGLLVLPSPINATSSLLESGGLYLIDTGQKIFLWFGKDAVPSLLQDLFGVDSLSDIPSgKFTLPPTGNEFNERVRN 802
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*...
gi 334187096 1022 AVNEIRRQ-RCSYLRIKLCKKG-EPSGML-FLSYMVEDRTASGPSYVEFLVQVHRQIQ 1076
Cdd:COG5028 803 IIGELRSVnDDSTLPLVLVRGGgDPSLRLwFFSTLVEDKTLNIPSYLDYLQILHEKIK 860
|
|
| Sec24-like |
cd01479 |
Sec24-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the ... |
502-746 |
3.44e-115 |
|
Sec24-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the budding and fusion of intracellular transport vesicles that selectively carry cargo proteins and lipids from donor to acceptor organelles. The two main classes of vesicular carriers within the endocytic and the biosynthetic pathways are COP- and clathrin-coated vesicles. Formation of COPII vesicles requires the ordered assembly of the coat built from several cytosolic components GTPase Sar1, complexes of Sec23-Sec24 and Sec13-Sec31. The process is initiated by the conversion of GDP to GTP by the GTPase Sar1 which then recruits the heterodimeric complex of Sec23 and Sec24. This heterodimeric complex generates the pre-budding complex. The final step leading to membrane deformation and budding of COPII-coated vesicles is carried by the heterodimeric complex Sec13-Sec31. The members of this CD belong to the Sec23-like family. Sec 24 is very similar to Sec23. The Sec23 and Sec24 polypeptides fold into five distinct domains: a beta-barrel, a zinc finger, a vWA or trunk, an all helical region and a carboxy Gelsolin domain. The members of this subgroup carry a partial MIDAS motif and have the overall Para-Rossmann type fold that is characteristic of this superfamily.
Pssm-ID: 238756 [Multi-domain] Cd Length: 244 Bit Score: 355.81 E-value: 3.44e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 502 PMPAVYFFLIDVSMNAIQTGATAAACNAIQQVLSDLP-EGPRTFVGIATFDSTIHFYNLKRALQQPLMLIVPDVQDVYTP 580
Cdd:cd01479 1 PQPAVYVFLIDVSYNAIKSGLLATACEALLSNLDNLPgDDPRTRVGFITFDSTLHFFNLKSSLEQPQMMVVSDLDDPFLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 581 LETDVVVQLSECRQHLELLLDSIPTMFQESKIPESAFGAAVKAAFLAMKSKGGKLMVFQSILCSVGVGALSSREAEGraN 660
Cdd:cd01479 81 LPDGLLVNLKESRQVIEDLLDQIPEMFQDTKETESALGPALQAAFLLLKETGGKIIVFQSSLPTLGAGKLKSREDPK--L 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 661 MSAGEKEAHklLQPADKTLKTMAIEFAEYQVCVDIFITTQAYVDMASISVIPRTTGGQVYCY--YPFSALSDPPKLYNDL 738
Cdd:cd01479 159 LSTDKEKQL--LQPQTDFYKKLALECVKSQISVDLFLFSNQYVDVATLGCLSRLTGGQVYYYpsFNFSAPNDVEKLVNEL 236
|
....*...
gi 334187096 739 KWNITRPQ 746
Cdd:cd01479 237 ARYLTRKI 244
|
|
| Sec23_trunk |
pfam04811 |
Sec23/Sec24 trunk domain; COPII-coated vesicles carry proteins from the endoplasmic reticulum ... |
502-742 |
2.30e-104 |
|
Sec23/Sec24 trunk domain; COPII-coated vesicles carry proteins from the endoplasmic reticulum to the Golgi complex. This vesicular transport can be reconstituted by using three cytosolic components containing five proteins: the small GTPase Sar1p, the Sec23p/24p complex, and the Sec13p/Sec31p complex. This domain is known as the trunk domain and has an alpha/beta vWA fold and forms the dimer interface.
Pssm-ID: 398467 [Multi-domain] Cd Length: 241 Bit Score: 326.90 E-value: 2.30e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 502 PMPAVYFFLIDVSMNAIQTGATAAACNAIQQVLSDLPEGPRTFVGIATFDSTIHFYNLKRALQQPLMLIVPDVQDVYTPL 581
Cdd:pfam04811 1 PQPPVFLFVIDVSYNAIKSGLLAALKESLLQSLDLLPGDPRARVGFITFDSTVHFFNLGSSLRQPQMLVVSDLQDMFLPL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 582 ETDVVVQLSECRQHLELLLDSIPTMFQESKIPESAFGAAVKAAFLAMKS--KGGKLMVFQSILCSVGV-GALSSREAEgr 658
Cdd:pfam04811 81 PDRFLVPLSECRFVLEDLLEQLPPMFPVTKRPERCLGPALQAAFLLLKAafTGGKIMVFQGGLPTVGPgGKLKSRLDE-- 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 659 aNMSAGEKEAHKLLQPADKTLKTMAIEFAEYQVCVDIFITTQAYVDMASISVIPRTTGGQVYCYYPFSALSDPPKLYNDL 738
Cdd:pfam04811 159 -SHHGTDKEKAKLVKKADKFYKSLAKECVKQGHSVDLFAFSLDYVDVATLGQLSRLTGGQVYLYPSFQADVDGSKFKQDL 237
|
....
gi 334187096 739 KWNI 742
Cdd:pfam04811 238 QRYF 241
|
|
| trunk_domain |
cd01468 |
trunk domain. COPII-coated vesicles carry proteins from the endoplasmic reticulum to the Golgi ... |
502-740 |
1.19e-93 |
|
trunk domain. COPII-coated vesicles carry proteins from the endoplasmic reticulum to the Golgi complex. This vesicular transport can be reconstituted by using three cytosolic components containing five proteins: the small GTPase Sar1p, the Sec23p/24p complex, and the Sec13p/Sec31p complex. This domain is known as the trunk domain and has an alpha/beta vWA fold and forms the dimer interface. Some members of this family possess a partial MIDAS motif that is a characteristic feature of most vWA domain proteins.
Pssm-ID: 238745 [Multi-domain] Cd Length: 239 Bit Score: 298.00 E-value: 1.19e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 502 PMPAVYFFLIDVSMNAIQTGATAAACNAIQQVLSDLPEGPRTFVGIATFDSTIHFYNLKRALQQPLMLIVPDVQDVYTPL 581
Cdd:cd01468 1 PQPPVFVFVIDVSYEAIKEGLLQALKESLLASLDLLPGDPRARVGLITYDSTVHFYNLSSDLAQPKMYVVSDLKDVFLPL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 582 ETDVVVQLSECRQHLELLLDSIPTMFQE--SKIPESAFGAAVKAAFLAMKSK--GGKLMVFQSILCSVGVGALSSREAEG 657
Cdd:cd01468 81 PDRFLVPLSECKKVIHDLLEQLPPMFWPvpTHRPERCLGPALQAAFLLLKGTfaGGRIIVFQGGLPTVGPGKLKSREDKE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 658 RANMSagekEAHKLLQPADKTLKTMAIEFAEYQVCVDIFITTQAYVDMASISVIPRTTGGQVYCYYPFSALSDPPKLYND 737
Cdd:cd01468 161 PIRSH----DEAQLLKPATKFYKSLAKECVKSGICVDLFAFSLDYVDVATLKQLAKSTGGQVYLYDSFQAPNDGSKFKQD 236
|
...
gi 334187096 738 LKW 740
Cdd:cd01468 237 LQR 239
|
|
| PTZ00395 |
PTZ00395 |
Sec24-related protein; Provisional |
499-1080 |
4.57e-43 |
|
Sec24-related protein; Provisional
Pssm-ID: 185594 [Multi-domain] Cd Length: 1560 Bit Score: 171.80 E-value: 4.57e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 499 VRDPMPAVYFFLIDVSMNAIQTGATAAACNAIQQVLSDLpEGPRTFVGIATFDSTIHFYNLKRALQQPL----------- 567
Cdd:PTZ00395 947 VKNMLPPYFVFVVECSYNAIYNNITYTILEGIRYAVQNV-KCPQTKIAIITFNSSIYFYHCKGGKGVSGeegdggggsgn 1025
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 568 --MLIVPDVQDVYTPLE-TDVVVQLSECRQHLELLLDSIPTMFQESKIPESAFGAAVKAAFLAMKSKGG--KLMVFQSIL 642
Cdd:PTZ00395 1026 hqVIVMSDVDDPFLPLPlEDLFFGCVEEIDKINTLIDTIKSVSTTMQSYGSCGNSALKIAMDMLKERNGlgSICMFYTTT 1105
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 643 CSVGVGALssreaegranmsageKEAHKLLQPADKTLK------TMAIEFAEYQVCVDIFI--TTQAYVDMASISVIPRT 714
Cdd:PTZ00395 1106 PNCGIGAI---------------KELKKDLQENFLEVKqkifydSLLLDLYAFNISVDIFIisSNNVRVCVPSLQYVAQN 1170
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 715 TGGQVYCYYPFSALSDPPKLYNDLKWNITRPQ-GFEAVMRVRCSQGIQVQEY---SGNFCKRIPTD-IDLPA--HD---- 783
Cdd:PTZ00395 1171 TGGKILFVENFLWQKDYKEIYMNIMDTLTSEDiAYCCELKLRYSHHMSVKKLfccNNNFNSIISVDtIKIPKirHDqtfa 1250
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 784 ------DKLQDGAECAFQCALLYTTIYGERRIRVTTLSLSCTNMLSNLFRAADLDSQFACMLKQAANEIpskalpLVKEQ 857
Cdd:PTZ00395 1251 fllnysDISESKKQIYFQCACIYTNLWGDRFVRLHTTHMNLTSSLSTVFRYTDAEALMNILIKQLCTNI------LHNDN 1324
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 858 ATNSCINA----LYAYRKFCATVTSSGQLILPEALKLFPLYTLALTKSVGLRTDGRIDDRSFwiNYVSSLSTPLAIPL-- 931
Cdd:PTZ00395 1325 YSKIIIDNlaaiLFSYRINCASSAHSGQLILPDTLKLLPLFTSSLLKHNVTKKEILHDLKVY--SLIKLLSMPIISSLly 1402
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 932 VYPRMISVH------DLDVKDTEGSV-LPPPIPLSSEHISNEGVYFLENGEDGLLFVGESVDSDilqklFAVSSAAEIPN 1004
Cdd:PTZ00395 1403 VYPVMYVIHikgktnEIDSMDVDDDLfIPKTIPSSAEKIYSNGIYLLDACTHFYLYFGFHSDAN-----FAKEIVGDIPT 1477
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 1005 QfvlqqyDNQLSKKFNDAVNEIRRQRC--SYLRIKLCKKGEPSGML---------FLSYMVEDRTASGPSYVEFLVQVHR 1073
Cdd:PTZ00395 1478 E------KNAHELNLTDTPNAQKVQRIikNLSRIHHFNKYVPLVMVapksneeehLISLCVEDKADKEYSYVNFLCFIHK 1551
|
....*..
gi 334187096 1074 QIQLKMN 1080
Cdd:PTZ00395 1552 LVHKRID 1558
|
|
| Sec23_helical |
pfam04815 |
Sec23/Sec24 helical domain; COPII-coated vesicles carry proteins from the endoplasmic ... |
830-930 |
6.32e-29 |
|
Sec23/Sec24 helical domain; COPII-coated vesicles carry proteins from the endoplasmic reticulum to the Golgi complex. This vesicular transport can be reconstituted by using three cytosolic components containing five proteins: the small GTPase Sar1p, the Sec23p/24p complex, and the Sec13p/Sec31p complex. This domain is composed of five alpha helices.
Pssm-ID: 461441 [Multi-domain] Cd Length: 103 Bit Score: 111.44 E-value: 6.32e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 830 DLDSQFACMLKQAANEIPSKALPLVKEQATNSCINALYAYRKFCATVTSSGQLILPEALKLFPLYTLALTKSVGLRTDG- 908
Cdd:pfam04815 1 DQEAIAVLLAKKAVEKALSSSLSDAREALDNKLVDILAAYRKYCASSSSPGQLILPESLKLLPLYMLALLKSPALRGGNs 80
|
90 100
....*....|....*....|...
gi 334187096 909 -RIDDRSFWINYVSSLSTPLAIP 930
Cdd:pfam04815 81 sPSDERAYARHLLLSLPVEELLL 103
|
|
| Sec23_BS |
pfam08033 |
Sec23/Sec24 beta-sandwich domain; |
747-819 |
1.61e-23 |
|
Sec23/Sec24 beta-sandwich domain;
Pssm-ID: 429794 [Multi-domain] Cd Length: 86 Bit Score: 95.30 E-value: 1.61e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 747 GFEAVMRVRCSQGIQVQEYSGNFCKRIPTD-IDLPA------------HDDKLQDGAECAFQCALLYTTIYGERRIRVTT 813
Cdd:pfam08033 1 GFNAVLRVRTSKGLKVSGFIGNFVSRSSGDtWKLPSldpdtsyafefdIDEPLPNGSNAYIQFALLYTHSSGERRIRVTT 80
|
....*.
gi 334187096 814 LSLSCT 819
Cdd:pfam08033 81 VALPVT 86
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
65-345 |
1.12e-18 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 92.69 E-value: 1.12e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 65 PQPFPQQSPSYGAPQRGPSPMSRPGPPAGMARPGGPPPVSQPAgfQSNVPLNRPTGPPSRQPsfgsRPSMPGGPVAQPAA 144
Cdd:PHA03247 2725 PAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPP--APAPPAAPAAGPPRRLT----RPAVASLSESRESL 2798
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 145 SSSGFPAFGPSGSVAAGP--PPGSRPmAFGSPPPVGSGMSMP--PSGMIGGPVSNGHQMVGSGGFPR--GTQFPGAAVTT 218
Cdd:PHA03247 2799 PSPWDPADPPAAVLAPAAalPPAASP-AGPLPPPTSAQPTAPppPPGPPPPSLPLGGSVAPGGDVRRrpPSRSPAAKPAA 2877
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 219 PQAPYVRPPSAPYARTPPQPLGSHSLSGNPPLTPFTAPSMPPPATFPGAPHGRPAVSglPYGPPSAQVAPPLGFPGQMQP 298
Cdd:PHA03247 2878 PARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPP--PPPRPQPPLAPTTDPAGAGEP 2955
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 334187096 299 PryGMGPLPnqsmtniptamgQPGATVPGP-----SRIDPNQIPRPGSSSSP 345
Cdd:PHA03247 2956 S--GAVPQP------------WLGALVPGRvavprFRVPQPAPSREAPASST 2993
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
3-365 |
1.99e-18 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 91.92 E-value: 1.99e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 3 APVPPGAPRPNsqqnsgPPNFYPGSQGNSNALADNMQNLSLNRPPPMMPGSGPRPPPPFGQSPQPFPQQSPsygaPQRGP 82
Cdd:PHA03247 2615 SPLPPDTHAPD------PPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSP----PQRPR 2684
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 83 SPMSRP--GPPAGMARPGGPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSMPGGPVAQPAASSSGFPAFGPSGSVAA 160
Cdd:PHA03247 2685 RRAARPtvGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTA 2764
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 161 GPPpgsrpmafgSPPPVGSGMSMPPSGMIGGPVSNGHQMVGSGGFPRGTQFPGAAVTTPqAPYVRPPSAPYARTPPQPLG 240
Cdd:PHA03247 2765 GPP---------APAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAP-AAALPPAASPAGPLPPPTSA 2834
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 241 SHSLSGNPPltPFTAPSMPPP-ATFPGAPHGRPAVSGLPYGPPSAQVAPP---LGFPGQMQPPRYGMGPLPNQSMTNIPT 316
Cdd:PHA03247 2835 QPTAPPPPP--GPPPPSLPLGgSVAPGGDVRRRPPSRSPAAKPAAPARPPvrrLARPAVSRSTESFALPPDQPERPPQPQ 2912
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 334187096 317 AMGQPGATVPGPSRIDPNQIPRPGSSSSPTVFETRQSNQANPPPPATSD 365
Cdd:PHA03247 2913 APPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQ 2961
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
4-364 |
9.47e-17 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 86.15 E-value: 9.47e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 4 PVPPGAPRPNSQQNSGPPNFYPGSQGNSnaladnmqnlSLNRPPPMMPGSGPRPPPPFGQSPQPFPQQSPSYGAPQRGPS 83
Cdd:PHA03247 2554 PLPPAAPPAAPDRSVPPPRPAPRPSEPA----------VTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHA 2623
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 84 PmsRPGPPAGMARPGGPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSMPGGPVAQPAA--SSSGFPAFGPSGSVAAG 161
Cdd:PHA03247 2624 P--DPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRprRRAARPTVGSLTSLADP 2701
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 162 PPPGSRPMAfgSPPPVGSGMSMPPsgmigGPVSNGhqmvGSGGFPRGTQFPGAAVTTPQAPY--VRPPSAPYARTPPQPl 239
Cdd:PHA03247 2702 PPPPPTPEP--APHALVSATPLPP-----GPAAAR----QASPALPAAPAPPAVPAGPATPGgpARPARPPTTAGPPAP- 2769
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 240 gshslsgNPPLTPFTAPsmPPPATFPGAPHGRPAVSGLPYGPPSAQVAPPLGFPGQMQPPRYGMGPLPNQSMTNIPTAMG 319
Cdd:PHA03247 2770 -------APPAAPAAGP--PRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP 2840
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 334187096 320 QPgatvPGPSridPNQIPRPGSSSSPTVFETRQSNQANPPPPATS 364
Cdd:PHA03247 2841 PP----PGPP---PPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAP 2878
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
65-364 |
2.65e-16 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 84.60 E-value: 2.65e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 65 PQPFPQQSPSYGAPQRGPSPMSRPGPP-----AGMARPGGPPPVSQPagfqsNVPLNrPTGPPSRQPSfgSRPSMPGGPV 139
Cdd:PHA03247 2552 PPPLPPAAPPAAPDRSVPPPRPAPRPSepavtSRARRPDAPPQSARP-----RAPVD-DRGDPRGPAP--PSPLPPDTHA 2623
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 140 AQPAASSSGFPAFGPSGSVAAGPPPGSRPMAFGSPPPVGSGMSMPPSGMIGGPVSNGHqmvgsGGFPRGTQFPGAAVTT- 218
Cdd:PHA03247 2624 PDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQ-----RPRRRAARPTVGSLTSl 2698
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 219 ------PQAPYVRPPsaPYARTPPQPLGSHSLSGNPPLTPfTAPSMPPPATFPGAPHG--RPAVSGLPYGPPSAqvAPPL 290
Cdd:PHA03247 2699 adppppPPTPEPAPH--ALVSATPLPPGPAAARQASPALP-AAPAPPAVPAGPATPGGpaRPARPPTTAGPPAP--APPA 2773
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 334187096 291 GFPGQMQP--PRYGMGPL-PNQSMTNIPTAMGQPGATVPGP-SRIDPNQIPRPGSSSSPTVFETRQSNQANPPPPATS 364
Cdd:PHA03247 2774 APAAGPPRrlTRPAVASLsESRESLPSPWDPADPPAAVLAPaAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP 2851
|
|
| zf-Sec23_Sec24 |
pfam04810 |
Sec23/Sec24 zinc finger; COPII-coated vesicles carry proteins from the endoplasmic reticulum ... |
427-464 |
1.79e-15 |
|
Sec23/Sec24 zinc finger; COPII-coated vesicles carry proteins from the endoplasmic reticulum to the Golgi complex. This vesicular transport can be reconstituted by using three cytosolic components containing five proteins: the small GTPase Sar1p, the Sec23p/24p complex, and the Sec13p/Sec31p complex. This domain is found to be zinc binding domain.
Pssm-ID: 461437 [Multi-domain] Cd Length: 38 Bit Score: 70.94 E-value: 1.79e-15
10 20 30
....*....|....*....|....*....|....*...
gi 334187096 427 PVRCSRCKGYINPFMKFIDQGRKFICNFCGYTDETPRD 464
Cdd:pfam04810 1 PVRCRRCRAYLNPFCQFDFGGKKWTCNFCGTRNPVPPE 38
|
|
| PLN00162 |
PLN00162 |
transport protein sec23; Provisional |
380-719 |
2.96e-12 |
|
transport protein sec23; Provisional
Pssm-ID: 215083 [Multi-domain] Cd Length: 761 Bit Score: 71.12 E-value: 2.96e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 380 RCTINQIPCTVDLLSTSGMQLALMVQPLalSHPSEEPIQVVDfgeggPVRCSRCKGYINPFMKFIDQGRKFICNFCGYTD 459
Cdd:PLN00162 13 RMSWNVWPSSKIEASKCVIPLAALYTPL--KPLPELPVLPYD-----PLRCRTCRAVLNPYCRVDFQAKIWICPFCFQRN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 460 ETPRDYHC----NLgPdgrrrdvderPEL--CRGTVEFVATKEyMVRDPMPAVYFFLIDVSMNAIQTGataAACNAIQQV 533
Cdd:PLN00162 86 HFPPHYSSisetNL-P----------AELfpQYTTVEYTLPPG-SGGAPSPPVFVFVVDTCMIEEELG---ALKSALLQA 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 534 LSDLPEGprTFVGIATFDSTIHFYNL----------------------------KRALQQPLMLIVPDVQDvytPLETDV 585
Cdd:PLN00162 151 IALLPEN--ALVGLITFGTHVHVHELgfsecsksyvfrgnkevskdqileqlglGGKKRRPAGGGIAGARD---GLSSSG 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 586 V----VQLSECRQHLELLLDSI---PTMFQESKIPESAFGAA--VKAAFLA--MKSKGGKLMVFQSILCSVGVGALSSRE 654
Cdd:PLN00162 226 VnrflLPASECEFTLNSALEELqkdPWPVPPGHRPARCTGAAlsVAAGLLGacVPGTGARIMAFVGGPCTEGPGAIVSKD 305
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 334187096 655 aegranMSAG-------EKEAHKLLQPADKTLKTMAIEFAEYQVCVDIFITTQAYVDMASISVIPRTTGGQV 719
Cdd:PLN00162 306 ------LSEPirshkdlDKDAAPYYKKAVKFYEGLAKQLVAQGHVLDVFACSLDQVGVAEMKVAVERTGGLV 371
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
87-299 |
5.66e-12 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 70.01 E-value: 5.66e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 87 RPGPPAGMARPGGPPPvsqPAGFQSNVPLNRPTGPPsrQPSFGSRPSmPGGPVAQPAASSSGFPAFGPSGSVAAGPPPGS 166
Cdd:PRK07764 587 VVGPAPGAAGGEGPPA---PASSGPPEEAARPAAPA--APAAPAAPA-PAGAAAAPAEASAAPAPGVAAPEHHPKHVAVP 660
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 167 RPMAFGSPPPVGSGMSMPpsgmiggpvsnghqmVGSGGFPRGTQFPGAAVTTPQAPYVRPPSAPYARTPPQPLGSHSLSG 246
Cdd:PRK07764 661 DASDGGDGWPAKAGGAAP---------------AAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAA 725
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 334187096 247 NPPLTPFTAPSMPPPAtfPGAPHGRPAVSGLPYGPPSAQVAPPLGFPGQMQPP 299
Cdd:PRK07764 726 QGASAPSPAADDPVPL--PPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPP 776
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
63-367 |
2.90e-11 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 67.87 E-value: 2.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 63 QSPQPFPQQSPSYGAPQRGPSPMSRPGPPAGMarpggPPPVSQPAGFQSNVPLNRPTGPPSRQPSfgsrPSMPGGPVAQP 142
Cdd:pfam03154 185 SPPPPGTTQAATAGPTPSAPSVPPQGSPATSQ-----PPNQTQSTAAPHTLIQQTPTLHPQRLPS----PHPPLQPMTQP 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 143 AASSSGFPAFGPSGSVAAGPPPGSRPMAFGsppPVGSGMSMPPSGMIGGPVSNGHQmvgsGGFPRGTQFPGAAVTTPQAP 222
Cdd:pfam03154 256 PPPSQVSPQPLPQPSLHGQMPPMPHSLQTG---PSHMQHPVPPQPFPLTPQSSQSQ----VPPGPSPAAPGQSQQRIHTP 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 223 yvRPPSAPYARTPP--QPLgshslsgnpPLTPFTAPSMPPPATFPGAPHGRPAVSGlpyGPPSAQVAPPLGFPGQMQPPR 300
Cdd:pfam03154 329 --PSQSQLQSQQPPreQPL---------PPAPLSMPHIKPPPTTPIPQLPNPQSHK---HPPHLSGPSPFQMNSNLPPPP 394
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 334187096 301 yGMGPLPNQSMTNIPTAMGQPGATVPGPSRIDPNQIPRPGSSSSPTVfetrQSNQANPPPPATSDYV 367
Cdd:pfam03154 395 -ALKPLSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQSQSL----PPPAASHPPTSGLHQV 456
|
|
| SEC23 |
COG5047 |
Vesicle coat complex COPII, subunit SEC23 [Intracellular trafficking and secretion]; |
379-943 |
3.71e-11 |
|
Vesicle coat complex COPII, subunit SEC23 [Intracellular trafficking and secretion];
Pssm-ID: 227380 [Multi-domain] Cd Length: 755 Bit Score: 67.21 E-value: 3.71e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 379 MRCTINQIPCTVDLLSTSGMQLALMVQPLalsHPSEEpiqvVDFGEGGPVRC-SRCKGYINPFMKfIDQGRKF-ICNFCG 456
Cdd:COG5047 12 IRLTWNVFPATRGDATRTVIPIACLYTPL---HEDDA----LTVNYYEPVKCtAPCKAVLNPYCH-IDERNQSwICPFCN 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 457 YTDETPRDYHcNLGPDgrrrdvDERPELCR--GTVEFVATKEYMVrdpmPAVYFFLIDVsmnAIQTGATAAACNAIQQVL 534
Cdd:COG5047 84 QRNTLPPQYR-DISNA------NLPLELLPqsSTIEYTLSKPVIL----PPVFFFVVDA---CCDEEELTALKDSLIVSL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 535 SDLPEGPrtFVGIATFDSTIHFYNL------------------KRALQQPLMLIVPDV----------QDVYTPLETDVV 586
Cdd:COG5047 150 SLLPPEA--LVGLITYGTSIQVHELnaenhrrsyvfsgnkeytKENLQELLALSKPTKsggfeskisgIGQFASSRFLLP 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 587 VQlsECRQHLELLLDSI-PTMFQ--ESKIPESAFGAAVKAAFLAM----KSKGGKLMVFQSILCSVGVGALSSRE-AEGR 658
Cdd:COG5047 228 TQ--QCEFKLLNILEQLqPDPWPvpAGKRPLRCTGSALNIASSLLeqcfPNAGCHIVLFAGGPCTVGPGTVVSTElKEPM 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 659 ANMSAGEKEAHKLLQPADKTLKTMAIEFAEYQVCVDIFITTQAYVDMASISVIPRTTGGQVYCYYPFSA---LSDPPKLY 735
Cdd:COG5047 306 RSHHDIESDSAQHSKKATKFYKGLAERVANQGHALDIFAGCLDQIGIMEMEPLTTSTGGALVLSDSFTTsifKQSFQRIF 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 736 NDLKWNITRpQGFEAVMRVRCSQGIQVQEYSGN---FCKR-----------------------------IPTDIDLPAHD 783
Cdd:COG5047 386 NRDSEGYLK-MGFNANMEVKTSKNLKIKGLIGHavsVKKKannisdseigigatnswkmaslspksnyaLYFEIALGAAS 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 784 DKLQDGAECAFQCALLYTTIYGERRIRVTTLSLSCTNM-LSNLFRAADLDSQFACMLKQAANEIPSKALPLVKEQATNSC 862
Cdd:COG5047 465 GSAQRPAEAYIQFITTYQHSSGTYRIRVTTVARMFTDGgLPKINRSFDQEAAAVFMARIAAFKAETEDIIDVFRWIDRNL 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 863 INALYAYRKFCATVTSSgqLILPEALKLFPLYTLALTKSVGLRT-DGRIDDRSFWINYVSSLSTPLAIPLVYPRMISVHD 941
Cdd:COG5047 545 IRLCQKFADYRKDDPSS--FRLDPNFTLYPQFMYHLRRSPFLSVfNNSPDETAFYRHMLNNADVNDSLIMIQPTLQSYSF 622
|
..
gi 334187096 942 LD 943
Cdd:COG5047 623 EK 624
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
77-362 |
5.44e-11 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 67.01 E-value: 5.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 77 APQRGPSPMSRPGPPAGMARPGGPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRP-------SMPGGPVAQPAASSSGF 149
Cdd:PHA03378 516 MEQRVMATLLPPSPPQPRAGRRAPCVYTEDLDIESDEPASTEPVHDQLLPAPGLGPlqiqpltSPTTSQLASSAPSYAQT 595
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 150 PAFGPSGSVAAGPPPG-SRPMAFGSPppvgSGMSMPPSGMIGGPVSNGHQMVGSGGFPRGTQFPGAAVTTPQAPYVRPPS 228
Cdd:PHA03378 596 PWPVPHPSQTPEPPTTqSHIPETSAP----RQWPMPLRPIPMRPLRMQPITFNVLVFPTPHQPPQVEITPYKPTWTQIGH 671
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 229 APYARTPPQPLGSHSLSGNPPL--TPFTAPS-MPPPATFPGaPHGRPAVSGLPYGPPSA---QVAPPLGFPGQMQPPRYG 302
Cdd:PHA03378 672 IPYQPSPTGANTMLPIQWAPGTmqPPPRAPTpMRPPAAPPG-RAQRPAAATGRARPPAAapgRARPPAAAPGRARPPAAA 750
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 334187096 303 MGPL--PNQSMTNIPTAMGQPGATVPGP---SRIDPNQIPRPGSSSSPTVFETRQSNQANPPPPA 362
Cdd:PHA03378 751 PGRArpPAAAPGRARPPAAAPGAPTPQPppqAPPAPQQRPRGAPTPQPPPQAGPTSMQLMPRAAP 815
|
|
| Gelsolin |
pfam00626 |
Gelsolin repeat; |
949-1014 |
7.13e-11 |
|
Gelsolin repeat;
Pssm-ID: 395501 [Multi-domain] Cd Length: 76 Bit Score: 59.24 E-value: 7.13e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 334187096 949 GSVLPPPIPLSSEHISNEGVYFLENGEDGLLFVGEsvDSDILQKLFAVSSAAEIPNQ--FVLQQYDNQ 1014
Cdd:pfam00626 1 KFVLPPPVPLSQESLNSGDCYLLDNGFTIFLWVGK--GSSLLEKLFAALLAAQLDDDerFPLPEVIRV 66
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
65-359 |
7.20e-11 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 66.57 E-value: 7.20e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 65 PQPFPQQSPSYGAPQRGPSPMSRPGPPAGMARPGGPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSM--------PG 136
Cdd:pfam09606 73 GGGQQGMPDPINALQNLAGQGTRPQMMGPMGPGPGGPMGQQMGGPGTASNLLASLGRPQMPMGGAGFPSQmsrvgrmqPG 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 137 GPVAQPAASSSGFPAFGPSGSVAAGPPPGsRPMAFGSPPPVGSGMSMPPSGMIGGPVSNGHQMVGSGGfprGTQFPGAAV 216
Cdd:pfam09606 153 GQAGGMMQPSSGQPGSGTPNQMGPNGGPG-QGQAGGMNGGQQGPMGGQMPPQMGVPGMPGPADAGAQM---GQQAQANGG 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 217 TTPQAPYVRPPSAPYARTPPQPLGSHS---LSGNPPLTPFTAPSMPPPATFPGAPHGRPAVSGLPYGPPSAQVAPPLGFP 293
Cdd:pfam09606 229 MNPQQMGGAPNQVAMQQQQPQQQGQQSqlgMGINQMQQMPQGVGGGAGQGGPGQPMGPPGQQPGAMPNVMSIGDQNNYQQ 308
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 294 GQMQPPRYGM-GPLPNQSMTNIPTAMGQPGATVP---------------GPSRIDPNQIPRPGSSSSPTVFETRQSNQAN 357
Cdd:pfam09606 309 QQTRQQQQQQgGNHPAAHQQQMNQSVGQGGQVVAlgglnhletwnpgnfGGLGANPMQRGQPGMMSSPSPVPGQQVRQVT 388
|
..
gi 334187096 358 PP 359
Cdd:pfam09606 389 PN 390
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
3-307 |
7.46e-11 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 66.89 E-value: 7.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 3 APVPPGAPRPNSQQNSGPPNFYPGSQGNSNALADNMQNLSLNRPPPMMPGSGPRPPPPFGQSPQPF--PQQSPSYGAPQR 80
Cdd:PHA03247 2762 TTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPlpPPTSAQPTAPPP 2841
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 81 GPSPMSRPGPPAGMARPGGPPPVSQPAGFQSNVPLNRPTGPPSRQPsfgsRPSMPGGPVAQPAASSSGFPAFGPSGSVAA 160
Cdd:PHA03247 2842 PPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLA----RPAVSRSTESFALPPDQPERPPQPQAPPPP 2917
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 161 GPPPGSRPMAFGSPPPVGSGMSMPPSGMIGGPVSNGHQMVGSGGFPRGTQFPG-AAVTTPQAPYVRpPSAPYARTPPQPL 239
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGrVAVPRFRVPQPA-PSREAPASSTPPL 2996
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 240 GSHSLSGNPPLTPFTA---PSMPPPATF------PGAPHGRPAVSGL------------------PYGPPSAQVAPPLGF 292
Cdd:PHA03247 2997 TGHSLSRVSSWASSLAlheETDPPPVSLkqtlwpPDDTEDSDADSLFdsdsersdlealdplppePHDPFAHEPDPATPE 3076
|
330
....*....|....*
gi 334187096 293 PGQMQPPRYGMGPLP 307
Cdd:PHA03247 3077 AGARESPSSQFGPPP 3091
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
63-362 |
4.44e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 63.85 E-value: 4.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 63 QSPQPFPQQSPSYGAPQRGPSPMSRPGPPAGMARPGGPPPVSQPAGFQSNVPLNRPTGPPSrqpsfGSRPSMPGGPVAQP 142
Cdd:PRK07764 398 APSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPP-----AAAPSAQPAPAPAA 472
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 143 AASSSGFPAfgPSGSVAAGPPPGSRPMAFGSPPPVGSGMSMP---------------------------PSGMIGGPVSN 195
Cdd:PRK07764 473 APEPTAAPA--PAPPAAPAPAAAPAAPAAPAAPAGADDAATLrerwpeilaavpkrsrktwaillpeatVLGVRGDTLVL 550
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 196 GH------QMVGSGGFPR----------GTQF---------PGAAVTTPQAPYVRPPSAPYARTPPQPLGSHSLSGNPPL 250
Cdd:PRK07764 551 GFstgglaRRFASPGNAEvlvtalaeelGGDWqveavvgpaPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPA 630
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 251 TPFTAPSMPPPATFPGAPHGRPAVSGLPYGPPSAQVAPPLGFPGQMQPPRYGMGPLPNQSMTNIPTAMGQPGATVPGPSR 330
Cdd:PRK07764 631 GAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPP 710
|
330 340 350
....*....|....*....|....*....|..
gi 334187096 331 IDPNQIPRPGSSSSPTVFETRQSNQANPPPPA 362
Cdd:PRK07764 711 AGQADDPAAQPPQAAQGASAPSPAADDPVPLP 742
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
4-343 |
4.58e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 64.19 E-value: 4.58e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 4 PVPPGAPrpNSQQNSGPPNFYPGSQGNSNALADNMQNLSLNRPPPMMPGSGPRPPPPFGQSPQPfpqqspsygapqRGPS 83
Cdd:PHA03247 2720 PLPPGPA--AARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPR------------RLTR 2785
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 84 PmsrPGPPAGMARPGGPPPvSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSMPGGPVAQPAASSSGFPAFGPSGSVAAGPP 163
Cdd:PHA03247 2786 P---AVASLSESRESLPSP-WDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGD 2861
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 164 PGSRPMAfGSPPPVGSGMSMPPSGMIGGPvsnghqmvgsggfprgtqfpgaAVTTPQAPYVRPPSAPyaRTPPQPLGSHS 243
Cdd:PHA03247 2862 VRRRPPS-RSPAAKPAAPARPPVRRLARP----------------------AVSRSTESFALPPDQP--ERPPQPQAPPP 2916
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 244 LSGNPPLTPFTAPSMPPPAtfPGAPHGRPAVSGLPYGPPSAQVAPPLGFPGQMQPPRYgmgplpnqSMTNIPTAMGQPGA 323
Cdd:PHA03247 2917 PQPQPQPPPPPQPQPPPPP--PPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRV--------AVPRFRVPQPAPSR 2986
|
330 340
....*....|....*....|
gi 334187096 324 TVPGPSRIDPNQIPRPGSSS 343
Cdd:PHA03247 2987 EAPASSTPPLTGHSLSRVSS 3006
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
2-361 |
5.31e-10 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 63.63 E-value: 5.31e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 2 VAPVPPGAPRPNSQQNSGPPNFYPG-SQGNSNALADNMQNLSLNRPPPMMPGSGPRPPPPFGQSPQPFPQQS-----PSY 75
Cdd:pfam03154 181 ASPPSPPPPGTTQAATAGPTPSAPSvPPQGSPATSQPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMtqpppPSQ 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 76 GAPQRGPSP-MSRPGPPAGMARPGGPPPVSQPA---GFQSNVPLNRPTGPPSRQPSF-GSRPSMPGGPVAQPAASSSGFP 150
Cdd:pfam03154 261 VSPQPLPQPsLHGQMPPMPHSLQTGPSHMQHPVppqPFPLTPQSSQSQVPPGPSPAApGQSQQRIHTPPSQSQLQSQQPP 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 151 AFGPSgsvaagpPPGSRPMAFGSPPPVgsgmsmPPSGMIGGPVSNGHQMVGSGgfPRGTQFPGaavTTPQAPYVRPPSA- 229
Cdd:pfam03154 341 REQPL-------PPAPLSMPHIKPPPT------TPIPQLPNPQSHKHPPHLSG--PSPFQMNS---NLPPPPALKPLSSl 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 230 -----PYARTPPQPLGSHSLSGNPP------LT-----PFTAPSMPPPATFPGAPHGRP--AVSGLPYGPPSaqVAPPLG 291
Cdd:pfam03154 403 sthhpPSAHPPPLQLMPQSQQLPPPpaqppvLTqsqslPPPAASHPPTSGLHQVPSQSPfpQHPFVPGGPPP--ITPPSG 480
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 292 FPGQMQPPRYGMGPLPNQSMTNIPTAMGQPGATVPgPSRIDPNQIPRPGSSSSPtvfetrqsnqanPPPP 361
Cdd:pfam03154 481 PPTSTSSAMPGIQPPSSASVSSSGPVPAAVSCPLP-PVQIKEEALDEAEEPESP------------PPPP 537
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
64-367 |
7.47e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 63.08 E-value: 7.47e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 64 SPQPFPQQSPSYGAPQRGPSPMSRPgPPAGMARPGGPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSMPGGPVAQPA 143
Cdd:PRK07764 405 APAAAPAPAAAAPAAAAAPAPAAAP-QPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPA 483
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 144 ASSSGFPAFGPSGSVAAGPPPGSRPMAF--GSPPPV------GSGMSMP-------PSGMIGGPVSNGH------QMVGS 202
Cdd:PRK07764 484 PPAAPAPAAAPAAPAAPAAPAGADDAATlrERWPEIlaavpkRSRKTWAillpeatVLGVRGDTLVLGFstgglaRRFAS 563
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 203 GGFPR----------GTQF---------PGAAVTTPQAPYVRPPSAPYARTPPQPLGSHSLSGNPPLTPFTAPSMPPPAT 263
Cdd:PRK07764 564 PGNAEvlvtalaeelGGDWqveavvgpaPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAP 643
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 264 FPGAPHGRPAVSGLPYGPPSAQVAPPLGFPGQMQPPRYGMGPLPNQSMTNIPTAMGQPGATVPGPsridpnqiPRPGSSS 343
Cdd:PRK07764 644 APGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAAT--------PPAGQAD 715
|
330 340
....*....|....*....|....
gi 334187096 344 SPTVFETRQSNQANPPPPATSDYV 367
Cdd:PRK07764 716 DPAAQPPQAAQGASAPSPAADDPV 739
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
66-320 |
2.88e-09 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 61.32 E-value: 2.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 66 QPFPQQSPSYGAPQRGPSPMSRPGPPAGMARPGGPPPVSQPagfqsnVPlNRPTGPPSRQPSFGSRPSMPGGPVAQPAAs 145
Cdd:pfam03154 322 QQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTP------IP-QLPNPQSHKHPPHLSGPSPFQMNSNLPPP- 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 146 ssgfPAFGPSGSVAAGPPPGSRpmafgsPPPVgsgMSMPPSGMIGGPVSNGHQMVGSGGFPRgtqfPGAAVTTPQAPYVR 225
Cdd:pfam03154 394 ----PALKPLSSLSTHHPPSAH------PPPL---QLMPQSQQLPPPPAQPPVLTQSQSLPP----PAASHPPTSGLHQV 456
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 226 PPSAPYARTPPQPLGSHSL---SGNPPLTPFTAPSMPPPATFPGAPHGR-PAVSGLPYGPPSAQVAPPLGFPGQMQPPRY 301
Cdd:pfam03154 457 PSQSPFPQHPFVPGGPPPItppSGPPTSTSSAMPGIQPPSSASVSSSGPvPAAVSCPLPPVQIKEEALDEAEEPESPPPP 536
|
250
....*....|....*....
gi 334187096 302 GMGPLPNQSMTNIPTAMGQ 320
Cdd:pfam03154 537 PRSPSPEPTVVNTPSHASQ 555
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
18-364 |
4.40e-09 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 60.96 E-value: 4.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 18 SGPPNFYPGSQGNSNALADNMQNLSLNRPPPMMPGSGPRPPPPFGQSPQPFPQQSPSYGAPqRGPSPMSRPGPPAGMArP 97
Cdd:PHA03307 37 SGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAP-ASPAREGSPTPPGPSS-P 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 98 GGPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSMPGGPVAQPAASSSGFPAFGPSGSVAAGPPPGSRPmafGSPPPV 177
Cdd:PHA03307 115 DPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARA---PSSPPA 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 178 GSGMSMPPSGMIGGPvsnghqmvGSGGFPRGTQFPGAAVTTPQAPYVRPPSAPYARTPPQPLGS----HSLSGNPPLTPF 253
Cdd:PHA03307 192 EPPPSTPPAAASPRP--------PRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCgwgpENECPLPRPAPI 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 254 TAPSmPPPATFPGAPHGRPAVSGLPYGPPSAQVAPPlgfpgqmQPPRYGMGPLPNQSmTNIPTAMGQPGATVPGPSRIDP 333
Cdd:PHA03307 264 TLPT-RIWEASGWNGPSSRPGPASSSSSPRERSPSP-------SPSSPGSGPAPSSP-RASSSSSSSRESSSSSTSSSSE 334
|
330 340 350
....*....|....*....|....*....|....
gi 334187096 334 ---NQIPRPGSSSSPTVFETRQSNQANPPPPATS 364
Cdd:PHA03307 335 ssrGAAVSPGPSPSRSPSPSRPPPPADPSSPRKR 368
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
122-348 |
8.44e-09 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 59.50 E-value: 8.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 122 PSRQPSFGSRPSMPGGPVAQPAASSSGFPAFGPSGSVAAGPPPGSRPMAFGSPPPVGSGMSMPPSgMIGGPVSNGHQMVG 201
Cdd:PRK12323 365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPA-PEALAAARQASARG 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 202 SGGFPRgtqfPGAAVTTPQAPYVRPPSAPyARTPPQPLGSHSLSGNPPLTPFTAPSMPPPatFPGAPHGRPAVSGLPYGP 281
Cdd:PRK12323 444 PGGAPA----PAPAPAAAPAAAARPAAAG-PRPVAAAAAAAPARAAPAAAPAPADDDPPP--WEELPPEFASPAPAQPDA 516
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 334187096 282 -PSAQVAPPLGFPGQMQPPRygmgplPNQSMTNIPTAMGQPGATVPgPSRIDPNQIPRPGSSSSPTVF 348
Cdd:PRK12323 517 aPAGWVAESIPDPATADPDD------AFETLAPAPAAAPAPRAAAA-TEPVVAPRPPRASASGLPDMF 577
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
67-366 |
1.82e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 58.84 E-value: 1.82e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 67 PFPQQSPSYGAPQRGPSPMSRPGPPAGMARPG-GPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSMPGGPVAQPAAS 145
Cdd:PRK07764 418 AAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPaGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAP 497
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 146 SSGFPAFGP-----------------------------SGSVAAGPPPGSRPMAFGSPPPVgsgmsmppsGMIGGPVSNG 196
Cdd:PRK07764 498 AAPAAPAGAddaatlrerwpeilaavpkrsrktwaillPEATVLGVRGDTLVLGFSTGGLA---------RRFASPGNAE 568
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 197 ------HQMVG-----------SGGFPRGTQFPGAAVTTPQAPYVRPPSAPYARTPPQPLGSHSLSGNPPLTPFTAPSMP 259
Cdd:PRK07764 569 vlvtalAEELGgdwqveavvgpAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVA 648
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 260 PPATFPGAPHGRPAVSGLPYGPPSAQVAPPLGFPGQMQPPrygmGPLPNQSMTNIPTAMGQPGATVPGPSRIDPNQIPRP 339
Cdd:PRK07764 649 APEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPA----APAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQA 724
|
330 340
....*....|....*....|....*..
gi 334187096 340 GSSSSPtvfeTRQSNQANPPPPATSDY 366
Cdd:PRK07764 725 AQGASA----PSPAADDPVPLPPEPDD 747
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
69-290 |
3.01e-08 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 57.96 E-value: 3.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 69 PQQSPSYGAPQRGPS-PMSRPGPPAGMARPGGPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSrPSMPGGPVAQPAASSS 147
Cdd:PRK12323 365 PGQSGGGAGPATAAAaPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRS-PAPEALAAARQASARG 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 148 GFPAFGPSGSVAAGPPPGSRPMAFGSPPPVGSGMSMPPSGMIGGPVSNGHQmvgsgGFPRGTQFPGA-AVTTPQAPYVRP 226
Cdd:PRK12323 444 PGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADD-----DPPPWEELPPEfASPAPAQPDAAP 518
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 334187096 227 PSAPYARTPPQPLGSHSLSGNPPLTPFTAPSMPPPA--TFPGAPHGRPAVSGLPYGPPSAQVAPPL 290
Cdd:PRK12323 519 AGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAaaTEPVVAPRPPRASASGLPDMFDGDWPAL 584
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
64-262 |
3.25e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 57.69 E-value: 3.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 64 SPQPFPQQSPS-YGAPQRGPSPmSRPGPPAGMARPGGPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSMPGGPVAQP 142
Cdd:PRK07764 600 PPAPASSGPPEeAARPAAPAAP-AAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAP 678
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 143 AASS-SGFPAFGPSGSVAAGPPPGSRPMAFGSPPPVGSGMSMPPSGMIGG--PVSNGHQMVGSGGFPRGTQFPGAAVTTP 219
Cdd:PRK07764 679 AAPPpAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGAsaPSPAADDPVPLPPEPDDPPDPAGAPAQP 758
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 334187096 220 QAPYVRPPSAPYARTPPQPlgshSLSGNPPLTPFTAPSMPPPA 262
Cdd:PRK07764 759 PPPPAPAPAAAPAAAPPPS----PPSEEEEMAEDDAPSMDDED 797
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
71-371 |
5.72e-08 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 57.10 E-value: 5.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 71 QSPSYGAPQ--------RGPSPMSRPGPPAGMARPGGPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSMPGGPVAQP 142
Cdd:PHA03307 33 DDLLSGSQGqlvsdsaeLAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPS 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 143 aaSSSGFPAFGPSGSVAAGPPPGSRPMAFGSPPPVGSGMSMPPsgmiggPVSNGHQMVGSGGF-PRGTQFPGAAVTTPQA 221
Cdd:PHA03307 113 --SPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPP------AAGASPAAVASDAAsSRQAALPLSSPEETAR 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 222 PYVRPPSAPYARTPPQPLGSHSLSGNPPLTPFTAPSMPPPATFPGAPHGRPAVSGLPYGPPSAQVAPPLGFPGqmqpPRY 301
Cdd:PHA03307 185 APSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPL----PRP 260
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 302 GMGPLPNQSMTNIPTAMGQPGATVPGPSRIDPNQIPRPGSSSSptvfetrqSNQANPPPPATSDYVVRDT 371
Cdd:PHA03307 261 APITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSP--------GSGPAPSSPRASSSSSSSR 322
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
160-364 |
9.48e-08 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 55.99 E-value: 9.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 160 AGPPPGSRPMAFGSPPPVGSGMSMPPSGMIGGPVSNGHQMvgsgGFPRGTQFPGAAVTTPQApYVRPPSAPYARTPPQPL 239
Cdd:PRK14086 92 AGEPAPPPPHARRTSEPELPRPGRRPYEGYGGPRADDRPP----GLPRQDQLPTARPAYPAY-QQRPEPGAWPRAADDYG 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 240 GSHSLSGNPPLTPFTAPSMPPPATFPGAPhgrpavsglPYGPPSAQVAPPLGFPGQmqpPRYGMGPlPNQSMTNIP---T 316
Cdd:PRK14086 167 WQQQRLGFPPRAPYASPASYAPEQERDRE---------PYDAGRPEYDQRRRDYDH---PRPDWDR-PRRDRTDRPeppP 233
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 334187096 317 AMGQPGATVPGPSRIDPNQIPrPGSSSSPTVFETRQSNQANPPPPATS 364
Cdd:PRK14086 234 GAGHVHRGGPGPPERDDAPVV-PIRPSAPGPLAAQPAPAPGPGEPTAR 280
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
130-363 |
9.62e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 56.87 E-value: 9.62e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 130 SRPSMPGGPVAQ-PAASSSGFPAFGPSGSVAAGPPPGSRPMAFGSPPPvgsgmSMPPSGMIGGPVS-------NGHQMVG 201
Cdd:PHA03247 2470 LGELFPGAPVYRrPAEARFPFAAGAAPDPGGGGPPDPDAPPAPSRLAP-----AILPDEPVGEPVHprmltwiRGLEELA 2544
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 202 S--GGFPRGTQFPGAAVTTP--QAPYVRP---PSAPYART-------PPQPLGSHSL---SGNPPLTPftAPSMPPPATF 264
Cdd:PHA03247 2545 SddAGDPPPPLPPAAPPAAPdrSVPPPRPaprPSEPAVTSrarrpdaPPQSARPRAPvddRGDPRGPA--PPSPLPPDTH 2622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 265 ---PGAPHGRPAVSGLPYGPPSAQVAPPLGF----PGQMQPPRYGMGPLPNQSMTNIPTAMGQPGA--TV--------PG 327
Cdd:PHA03247 2623 apdPPPPSPSPAANEPDPHPPPTVPPPERPRddpaPGRVSRPRRARRLGRAAQASSPPQRPRRRAArpTVgsltsladPP 2702
|
250 260 270
....*....|....*....|....*....|....*.
gi 334187096 328 PSRIDPNQIPRPGSSSSPTVFETRQSNQANPPPPAT 363
Cdd:PHA03247 2703 PPPPTPEPAPHALVSATPLPPGPAAARQASPALPAA 2738
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
63-238 |
9.99e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 56.15 E-value: 9.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 63 QSPQPFPQQSPSYGAPQRGPSPMSRPGPPAGMARPGGPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSMPGGPvAQP 142
Cdd:PRK07764 623 APAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAP-AQP 701
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 143 AASSSGFPAFGPSGSVAAGPPPGSRpmAFGSPPPVGSGMSMPPSGMIGGPVSNGHqmvGSGGFPRGTQFPGAAVTTPQAP 222
Cdd:PRK07764 702 APAPAATPPAGQADDPAAQPPQAAQ--GASAPSPAADDPVPLPPEPDDPPDPAGA---PAQPPPPPAPAPAAAPAAAPPP 776
|
170
....*....|....*.
gi 334187096 223 YVRPPSAPYARTPPQP 238
Cdd:PRK07764 777 SPPSEEEEMAEDDAPS 792
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
3-262 |
1.51e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 55.95 E-value: 1.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 3 APVPPGAPRPNSQQNSGPPnfyPGSQGNSNALADNmQNLSLNRPPPMMPGSGPRPPPPFGQSPQPFPQQSPSYGAPQRGP 82
Cdd:PHA03307 185 APSSPPAEPPPSTPPAAAS---PRPPRRSSPISAS-ASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRP 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 83 SPMSRPGPPAGMARPG----GPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSMPGGPVAQPAASSSGFPAFGPSGSV 158
Cdd:PHA03307 261 APITLPTRIWEASGWNgpssRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAA 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 159 AAGPPPGSRPMAFGSPPPVGSGMSMPPSGMIGGPVSNGHQMVGSGGFPRGtqfpGAAVTTPQAPYVRPPSAPYARTPPQP 238
Cdd:PHA03307 341 VSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRA----RAAVAGRARRRDATGRFPAGRPRPSP 416
|
250 260 270
....*....|....*....|....*....|..
gi 334187096 239 LGSHSLSGN-----PPLTPFTAP---SMPPPA 262
Cdd:PHA03307 417 LDAGAASGAfyaryPLLTPSGEPwpgSPPPPP 448
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
78-347 |
1.54e-07 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 55.84 E-value: 1.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 78 PQRGPSPMSRP-GPPAGMARPGG-----PPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSMPGGPvAQPAASSSGFPA 151
Cdd:PHA03378 697 PPRAPTPMRPPaAPPGRAQRPAAatgraRPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGR-ARPPAAAPGAPT 775
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 152 fgPSGSVAAGPPPGSRPMAFGSP------PPVGSGMSMPPSGMIGGPVSNGHQMVGSGGFPRG---TQFPGAAvtTPQAP 222
Cdd:PHA03378 776 --PQPPPQAPPAPQQRPRGAPTPqpppqaGPTSMQLMPRAAPGQQGPTKQILRQLLTGGVKRGrpsLKKPAAL--ERQAA 851
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 223 YVRPPSapyartPPQPLGSHSLSgnppltpftAPSMPPPATFPGAPHGRPAVSglpyGPPSAQVAP--PLGFPGQmqppR 300
Cdd:PHA03378 852 AGPTPS------PGSGTSDKIVQ---------APVFYPPVLQPIQVMRQLGSV----RAAAASTVTqaPTEYTGE----R 908
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 334187096 301 YGMGPLPnqsMTNIPtamgqPGATVPGPSRIDPnQIPRPGSSSSPTV 347
Cdd:PHA03378 909 RGVGPMH---PTDIP-----PSKRAKTDAYVES-QPPHGGQSHSFSV 946
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
63-271 |
2.36e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 54.99 E-value: 2.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 63 QSPQPFPQQSPSYGAPQRGPSPMSRPGPPAGMARPGGPPPVSQPAGfqsnvplnRPTGPPSRQPSFGSRPSMPGGPVAQP 142
Cdd:PRK07764 611 EAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKH--------VAVPDASDGGDGWPAKAGGAAPAAPP 682
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 143 AASSSGFPafgPSGSVAAGPPPGSRPMAFGSPPPVGSGMSMPPSGMIGG--PVSNGHQMVGSGGFPRGTQFPGAAVTTPQ 220
Cdd:PRK07764 683 PAPAPAAP---AAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGAsaPSPAADDPVPLPPEPDDPPDPAGAPAQPP 759
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 334187096 221 apyvrPPSAPYARTPPQPlgshslsGNPPLTPFTAPSMPPPATFPGAPHGR 271
Cdd:PRK07764 760 -----PPPAPAPAAAPAA-------APPPSPPSEEEEMAEDDAPSMDDEDR 798
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
69-287 |
2.54e-07 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 54.88 E-value: 2.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 69 PQQSPSYGAPQRGPSPMSRPGPPAGMARPGGPPPVSQPAGFQSnvplnRPTGPPSRQPSFGSRPSMPGGPVAQPAASSSG 148
Cdd:PRK12323 397 PAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQA-----SARGPGGAPAPAPAPAAAPAAAARPAAAGPRP 471
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 149 FPAFGPSGSVAAGPPPGSRPMAFGSPPpvgsGMSMPPSGMIGGPVSNghqmvgSGGFPRGTQFPGAAVTTPQAPYVRPPS 228
Cdd:PRK12323 472 VAAAAAAAPARAAPAAAPAPADDDPPP----WEELPPEFASPAPAQP------DAAPAGWVAESIPDPATADPDDAFETL 541
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 334187096 229 APYARTPPQPLGSHSLSGNPPLTPFTAPSMPPPATFPGAPHGRPAvsGLPYGPPSAQVA 287
Cdd:PRK12323 542 APAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAA--RLPVRGLAQQLA 598
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
88-367 |
3.64e-07 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 54.47 E-value: 3.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 88 PGPPAGMARPGGPPPVsqpagfqsnVPLNRPTGPPSRQPSFGSRPSMPGGPVAQPAASSSGFPAFGPSGSVAAGPPPGSr 167
Cdd:PRK07003 360 PAVTGGGAPGGGVPAR---------VAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAA- 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 168 pmafgsPPPVGSGMSMPPSGMIGGPVSnghqmvGSGGFPRGTQFPGAAVTTPQAPYVRPPSAPYARTPPQPLGSHSLSGN 247
Cdd:PRK07003 430 ------PAPPATADRGDDAADGDAPVP------AKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAA 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 248 PPlTPFTAPSMPPPATFPGAPHG-RPAvsglPYGPPSAQVAPPLgfPGQMQPPRYGMGP------LPNQSM--------- 311
Cdd:PRK07003 498 AP-SAATPAAVPDARAPAAASREdAPA----AAAPPAPEARPPT--PAAAAPAARAGGAaaaldvLRNAGMrvssdrgar 570
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 334187096 312 --TNIPTAMGQPGATVPGPSRIdPNQIPRPGSSSSPTVFETR---------QSNQANPP----PPatSDYV 367
Cdd:PRK07003 571 aaAAAKPAAAPAAAPKPAAPRV-AVQVPTPRARAATGDAPPNgaaraeqaaESRGAPPPwediPP--DDYV 638
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
10-380 |
3.91e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 54.41 E-value: 3.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 10 PRPNSQQNSGPPNFYPGSQGNSNaladnmqnlSLNRPPPMMPGSGPRPPPPFGQSPQPFPQQSPSYGAPQRGPSPMSRPG 89
Cdd:PHA03307 65 FEPPTGPPPGPGTEAPANESRST---------PTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLS 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 90 PPAGMARPGGPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSrpSMPGGPVAQPAASSSGFPAFGPSGSVAAGPPPGSRPM 169
Cdd:PHA03307 136 EMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPL--SSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPI 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 170 AFGSPPPVGSGMSMPPSGMIGGPVSNGH-QMVGSGGFPRGTqfpgaaVTTPQAPYVRPPSAPYARTPPQPLGSHSLSGNP 248
Cdd:PHA03307 214 SASASSPAPAPGRSAADDAGASSSDSSSsESSGCGWGPENE------CPLPRPAPITLPTRIWEASGWNGPSSRPGPASS 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 249 PltpfTAPSMPPPATFPGAPHGRPAVSGLPYGPPSAQVAPP-LGFPGQMQPPRYGMGPLPNQSMTNIPTAMGQPGATVPG 327
Cdd:PHA03307 288 S----SSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESsSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPS 363
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 334187096 328 PSRIDPNQIPRPGSSSSPTVFETRQSNQANPPPPATSdyvvRDTGNCSPRYMR 380
Cdd:PHA03307 364 SPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARR----RDATGRFPAGRP 412
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
100-361 |
5.16e-07 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 53.89 E-value: 5.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 100 PPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSMPG-------GPVA--QPAASSSGFPAfGPSGSVAAGPPPGSRPMA 170
Cdd:pfam09770 107 PAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRTGyekykepEPIPdlQVDASLWGVAP-KKAAAPAPAPQPAAQPAS 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 171 FGSPPP-------VGSGMSMPPSgmiggpvsnghqmvgsggfPRGTQFPGAAVTTPQAPYVrPPSAPYARTPPQPLGSHS 243
Cdd:pfam09770 186 LPAPSRkmmsleeVEAAMRAQAK-------------------KPAQQPAPAPAQPPAAPPA-QQAQQQQQFPPQIQQQQQ 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 244 LSGNPPLTPFTAPSMPPPATFPGaPHGRPAVSGLPYGPPSAQVAPPLGFPGQMQPprygMGPLPNQSMtniptamgqpga 323
Cdd:pfam09770 246 PQQQPQQPQQHPGQGHPVTILQR-PQSPQPDPAQPSIQPQAQQFHQQPPPVPVQP----TQILQNPNR------------ 308
|
250 260 270
....*....|....*....|....*....|....*...
gi 334187096 324 tvPGPSRIDPNQIPRPGSSSSPTVFETRQSNQANPPPP 361
Cdd:pfam09770 309 --LSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGRQAP 344
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
61-365 |
7.13e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 53.64 E-value: 7.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 61 FGQSPQPFPQQSPSYGAPQRGPSPMSRPGPPAGMARPGGPPPVSQPAGFQSNVPLNRP--TGPPSRQPSFGSRPSMPGGP 138
Cdd:PHA03307 132 PDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPpaEPPPSTPPAAASPRPPRRSS 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 139 VAQPAASSsgfPAFGPSGSVAAGPPPGSRPMAFGSPPPVGSG-MSMPPSGMIGGPVSNGHQMVGSGGFPRGTQF-PGAAV 216
Cdd:PHA03307 212 PISASASS---PAPAPGRSAADDAGASSSDSSSSESSGCGWGpENECPLPRPAPITLPTRIWEASGWNGPSSRPgPASSS 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 217 TTPQAPYVRP----PSAPYARTPPQPLGSHSLS--GNPPLTPFTAPSMPPPATFPGAPHGRPAVSGLPygPPSAQVAPpl 290
Cdd:PHA03307 289 SSPRERSPSPspssPGSGPAPSSPRASSSSSSSreSSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRP--PPPADPSS-- 364
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 334187096 291 gfPGQMQPPRYGmGPLPNQSMTNIPTAMGQPGATVPGPSRIDPNQIPRPGSSSSPTVFETRQSNQANPPPPATSD 365
Cdd:PHA03307 365 --PRKRPRPSRA-PSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARYPLLTPS 436
|
|
| GGN |
pfam15685 |
Gametogenetin; GGN is a family of proteins largely found in mammals. It reacts with POG in the ... |
63-380 |
7.52e-07 |
|
Gametogenetin; GGN is a family of proteins largely found in mammals. It reacts with POG in the maturation of sperm and is expressed virtually only in the testis. It is found to be associated with the intracellular membrane, binds with GGNBP1 and may be involved in vesicular trafficking.
Pssm-ID: 434857 [Multi-domain] Cd Length: 668 Bit Score: 53.23 E-value: 7.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 63 QSPQP-----FPQQSPSYGAPQRGPSPMSRPGPPAGMARPGGPP-----PVSQPAGFQSNVPLNRPTGPPSRQPsfgSRP 132
Cdd:pfam15685 182 SDRQPpnrgiTPALATSATSPTDSQAKHIAEGKTAGGACGGAPPqagegEMARFAASESGLSLLCKVTFKSAAP---LCP 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 133 SMPGGPVAQPAA--SSSGFPAFGPSGSVAAGPPPGSRPMAFGSPPPVG---------SGMSMPPSGMIGGPVSNGHQMVG 201
Cdd:pfam15685 259 AAASGPLAAKASlgGGGGGGLFAASGAISCAEVLKQGPLAPGAARPLGevpraaletEGGEGDGEGCSGGPAAPASHARA 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 202 SGGfPRGTQFPGaavTTPQAPYVRPP--------------------------SAPYARTPPQPLGSHSLSG--------- 246
Cdd:pfam15685 339 LPP-PAYTTFPG---SKPKFDWVSPPdgperhfrfngagggigaprrraaalSGPWGSPPPPPGKAHPIPGprrpapall 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 247 NPPLTPFTAPSM------PPPAT---FPGAPHGRPAVSGLPYGPPSAQVAPPLGFP-GQMQPPRYGMGPLPNQSMTnipt 316
Cdd:pfam15685 415 APPMFIFPAPTNgepvrpGPPAPqalLPRPPPPTPPATPPPVPPPIPQLPALQPMPlAAARPPTPRPCPGHGESAL---- 490
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 334187096 317 amgQPGATVPGPSRIDPNQIPRPGSSSSPTVFETRQSNQANPPPPATSDYVVRDTGNCSPRYMR 380
Cdd:pfam15685 491 ---APAPTAPLPPALAADQAPAPALAAAPAPSPAPAPATADPLPPAPAPIKARTRKNKGPRAAR 551
|
|
| SOBP |
pfam15279 |
Sine oculis-binding protein; SOBP is associated with syndromic and nonsyndromic intellectual ... |
80-306 |
7.54e-07 |
|
Sine oculis-binding protein; SOBP is associated with syndromic and nonsyndromic intellectual disability. It carries a zinc-finger of the zf-C2H2 type at the N-terminus, and a highly characteriztic C-terminal PhPhPhPhPhPh motif. The deduced 873-amino acid protein contains an N-terminal nuclear localization signal (NLS), followed by 2 FCS-type zinc finger motifs, a proline-rich region (PR1), a putative RNA-binding motif region, and a C-terminal NLS embedded in a second proline-rich motif. SOBP is expressed in various human tissues, including developing mouse brain at embryonic day 14. In postnatal and adult mouse brain SOBP is expressed in all neurons, with intense staining in the limbic system. Highest expression is in layer V cortical neurons, hippocampus, pyriform cortex, dorsomedial nucleus of thalamus, amygdala, and hypothalamus. Postnatal expression of SOBP in the limbic system corresponds to a time of active synaptogenesis. the family is also referred to as Jackson circler, JXC1. In seven affected siblings from a consanguineous Israeli Arab family with mental retardation, anterior maxillary protrusion, and strabismus mutations were found in this protein.
Pssm-ID: 464609 [Multi-domain] Cd Length: 325 Bit Score: 52.51 E-value: 7.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 80 RGPSPMSR----PGPPAGMARPGGPPPVSQPagfqSNVPLNRPTgPPSRQPSFGSRPSmpgGPVAQPAASSSGFPAFGPS 155
Cdd:pfam15279 81 KSASPASTrsesVSPGPSSSASPSSSPTSSN----SSKPLISVA-SSSKLLAPKPHEP---PSLPPPPLPPKKGRRHRPG 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 156 GSVAAGPPPGSRPMAFGSPPPVGSGMSMPPSGMIggPVSNGHQMVgsggfPRGTQFPGAAVTTPQAPyVRPPSAPYARTP 235
Cdd:pfam15279 153 LHPPLGRPPGSPPMSMTPRGLLGKPQQHPPPSPL--PAFMEPSSM-----PPPFLRPPPSIPQPNSP-LSNPMLPGIGPP 224
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 334187096 236 PQPLGSHSLSGNPPLTP-FTAPSMPPPATFPGAPHGRPAVSGLPYGPPSAQVAPPLGFPGQMQPPRYGMGPL 306
Cdd:pfam15279 225 PKPPRNLGPPSNPMHRPpFSPHHPPPPPTPPGPPPGLPPPPPRGFTPPFGPPFPPVNMMPNPPEMNFGLPSL 296
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
72-289 |
1.07e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 53.25 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 72 SPSYGAPQRGPSPMSRPGPPAGMARPGGPPPVSQPAGFqsnvplnRPTGPPsrqpsfgsRPSMPGGPVAQPAASSSGFPA 151
Cdd:PHA03307 759 SNPSLVPAKLAEALALLEPAEPQRGAGSSPPVRAEAAF-------RRPGRL--------RRSGPAADAASRTASKRKSRS 823
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 152 FGPSGSVAAgPPPGSRPMAFGSPPPVGSGMSMPPSGMIGGPVSNGHQMVGSGGFPRGTQFPGAAVTTPQAPYVRPPSAPY 231
Cdd:PHA03307 824 HTPDGGSES-SGPARPPGAAARPPPARSSESSKSKPAAAGGRARGKNGRRRPRPPEPRARPGAAAPPKAAAAAPPAGAPA 902
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 334187096 232 ARTPPQPLgshslsgnPPLTPftapsMPppatfPGAPHGRPAVSGLPYGPPSAQVAPP 289
Cdd:PHA03307 903 PRPRPAPR--------VKLGP-----MP-----PGGPDPRGGFRRVPPGDLHTPAPSA 942
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
167-284 |
1.88e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 51.99 E-value: 1.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 167 RPMAFGSPPPVGSGMSMPPSGMIGGPVSNGHQMVgSGGFPRGTQFPGAAVTTPQAPYVRP-PSAPYARTPPQPlgshSLS 245
Cdd:PRK14959 372 RPSGGGASAPSGSAAEGPASGGAATIPTPGTQGP-QGTAPAAGMTPSSAAPATPAPSAAPsPRVPWDDAPPAP----PRS 446
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 334187096 246 GNPpltPFTAPSMPPPATFPGAPHGRPAVSGLP--YGPPSA 284
Cdd:PRK14959 447 GIP---PRPAPRMPEASPVPGAPDSVASASDAPptLGDPSD 484
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
6-222 |
5.31e-06 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 50.84 E-value: 5.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 6 PPGAPRPNSqqnsgPPNFYPGSQGNSNAladnmqnlSLNRPPPMMPGSGPRPPPPFGQSPQPFPQQSPS-----YGAPQR 80
Cdd:PHA03378 697 PPRAPTPMR-----PPAAPPGRAQRPAA--------ATGRARPPAAAPGRARPPAAAPGRARPPAAAPGrarppAAAPGR 763
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 81 GPSPMSRPGPPAGMarpggPPPVSQPAGFQ----SNVPLNRPTGPPS------RQPSFGSRPSMPGGPVAQPAASSSGFP 150
Cdd:PHA03378 764 ARPPAAAPGAPTPQ-----PPPQAPPAPQQrprgAPTPQPPPQAGPTsmqlmpRAAPGQQGPTKQILRQLLTGGVKRGRP 838
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 334187096 151 AFGPSGSVAAGPPPGSRPmafgsPPPVGSGMSMPPSGMIGGPVSNGHQMVGSGGFPRgtqfPGAAVTTPQAP 222
Cdd:PHA03378 839 SLKKPAALERQAAAGPTP-----SPGSGTSDKIVQAPVFYPPVLQPIQVMRQLGSVR----AAAASTVTQAP 901
|
|
| PPE |
COG5651 |
PPE-repeat protein [Function unknown]; |
90-308 |
2.37e-05 |
|
PPE-repeat protein [Function unknown];
Pssm-ID: 444372 [Multi-domain] Cd Length: 385 Bit Score: 47.97 E-value: 2.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 90 PPAGMARPGGPPPVSqpagfqsnvplNRPTGPPSRQPSFGSRPSMPGGPVAQPAASSSGFPAFGPSGSVAAGPPPGSRPM 169
Cdd:COG5651 170 PPPTITNPGGLLGAQ-----------NAGSGNTSSNPGFANLGLTGLNQVGIGGLNSGSGPIGLNSGPGNTGFAGTGAAA 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 170 AFGSPPPVGSGMSMPPSGMIGGPVSNGHQMVGSGGFPRGT--QFPGAAVTTPQAP--YVRPPSAPYARTPPQPLGSHSLS 245
Cdd:COG5651 239 GAAAAAAAAAAAAGAGASAALASLAATLLNASSLGLAATAasSAATNLGLAGSPLglAGGGAGAAAATGLGLGAGGAAGA 318
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 334187096 246 GNPPLTPFTAPSMPPPATfPGAPHGRPAVSGLPYGPPSAQVAPPLGFPGQMQPPRYGMGPLPN 308
Cdd:COG5651 319 AGATGAGAALGAGAAAAA-AGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASG 380
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
88-346 |
2.79e-05 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 48.54 E-value: 2.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 88 PGPPAgmarPGGPPPVSQPAGFQSNVPlnrptGPPSRQPSFGSRPS--MPGGPVAQPAASSSG-----FPAFGPSGSVAA 160
Cdd:PRK10263 342 QTPPV----ASVDVPPAQPTVAWQPVP-----GPQTGEPVIAPAPEgyPQQSQYAQPAVQYNEplqqpVQPQQPYYAPAA 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 161 GPPPGSRPMAFGSPPPVGSGMSMPPSGMIGGPVSNGHQmvgsggfPRGTQFPGAAVTTPQAPYVRPPSAPYARTPPQPLG 240
Cdd:PRK10263 413 EQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAE-------EQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVE 485
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 241 SHSLSGNPPLTPFTAPSMPPPATFPGAPHGR----------------PAVSGLPYGP----PSAQVAPPLGFPGQMQPPR 300
Cdd:PRK10263 486 QQPVVEPEPVVEETKPARPPLYYFEEVEEKRarereqlaawyqpipePVKEPEPIKSslkaPSVAAVPPVEAAAAVSPLA 565
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 334187096 301 YGMgplpnQSMTNIPTAMGQPGATV--------PGPS---RIDPnQIPRPGSSSSPT 346
Cdd:PRK10263 566 SGV-----KKATLATGAAATVAAPVfslansggPRPQvkeGIGP-QLPRPKRIRVPT 616
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
66-318 |
4.65e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.01 E-value: 4.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 66 QPFPQQSPSYGAPQRGPSPMSRPgPPAGMARPGGPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSMPGGPVAQPAAS 145
Cdd:PHA03247 235 EPFVERRVVISHPLRGDIAAPAP-PPVVGEGADRAPETARGATGPPPPPEAAAPNGAAAPPDGVWGAALAGAPLALPAPP 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 146 SsgfPAFGPSGSVAAGPPPGSRPMAFGSPPPvgsgmsmppsgmiggpvsnGHQMVGSGGFP---RGTQFPGAAVTTPQAP 222
Cdd:PHA03247 314 D---PPPPAPAGDAEEEDDEDGAMEVVSPLP-------------------RPRQHYPLGFPkrrRPTWTPPSSLEDLSAG 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 223 YVRPPSAP-------YARTPPQPLGSHSLSGNPPLTPFTAPSMPPPATFPGAPHGRPAVSGLPygPPSAQVAPPLG--FP 293
Cdd:PHA03247 372 RHHPKRASlptrkrrSARHAATPFARGPGGDDQTRPAAPVPASVPTPAPTPVPASAPPPPATP--LPSAEPGSDDGpaPP 449
|
250 260
....*....|....*....|....*
gi 334187096 294 GQMQPPRYGMGPLPNQSMTNIPTAM 318
Cdd:PHA03247 450 PERQPPAPATEPAPDDPDDATRKAL 474
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
3-177 |
4.76e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.67 E-value: 4.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 3 APVPPGAPRPNSQQNSGPPNFYPGSQGNSNALADNMQNLSLNRPPPMMPGSGPRPPPPFGQSPQPFPQQSPSYGAPQRGP 82
Cdd:PRK07764 606 SGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAP 685
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 83 SPMSRPGPPAGMARPGGPPPVSQPAGFQSNVPLNRPTGPP----SRQPSFGSRPSMPGGPVAQPAASSSGFPAFGPSGSV 158
Cdd:PRK07764 686 APAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAqgasAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPA 765
|
170
....*....|....*....
gi 334187096 159 AAGPPPGSRPMAFGSPPPV 177
Cdd:PRK07764 766 PAAAPAAAPPPSPPSEEEE 784
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
31-297 |
5.35e-05 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 47.34 E-value: 5.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 31 SNALADNMQNLSLNRPPPMMPGSGPRPPPPFGQSPQPFPQQSPSYGAPQR-GPSPMSRPGPPA---------GMARPGGP 100
Cdd:pfam09770 92 SDAIEEEQVRFNRQQPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVRtGYEKYKEPEPIPdlqvdaslwGVAPKKAA 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 101 PPVSQPAgfqsnvplnrPTGPPSRQPSfGSRPSM------------PGGPVAQPAASSSGFPAfgpsgsvaagPPPGSRP 168
Cdd:pfam09770 172 APAPAPQ----------PAAQPASLPA-PSRKMMsleeveaamraqAKKPAQQPAPAPAQPPA----------APPAQQA 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 169 MAFGSPPPVGSGMSMPpsgmiggpvsngHQMVGSGGFPRGTQFPGAAVTTPQAPYVrPPSAPYARTPPQPLGSHSLSGNP 248
Cdd:pfam09770 231 QQQQQFPPQIQQQQQP------------QQQPQQPQQHPGQGHPVTILQRPQSPQP-DPAQPSIQPQAQQFHQQPPPVPV 297
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 334187096 249 -PLTPFTAPSMPPPATFPGAPHGRPAVSGLPyGPPSAQVAPPLGFPGQMQ 297
Cdd:pfam09770 298 qPTQILQNPNRLSAARVGYPQNPQPGVQPAP-AHQAHRQQGSFGRQAPII 346
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
2-176 |
6.30e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.29 E-value: 6.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 2 VAPVPPGAPRPNSQQNSGPPNFYPGSQGNSNALADNMQNLSlnrPPPMMPGSGPRPPPPFGQSPQPFPQQSPSyGAPQRG 81
Cdd:PRK07764 625 AAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDG---GDGWPAKAGGAAPAAPPPAPAPAAPAAPA-GAAPAQ 700
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 82 PSPMSRPGPPAGMARPGGPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSMPGGPVAQPAASSSGFPAFGPSGSVAAG 161
Cdd:PRK07764 701 PAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPS 780
|
170
....*....|....*
gi 334187096 162 PPPGSRPMAFGSPPP 176
Cdd:PRK07764 781 EEEEMAEDDAPSMDD 795
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
208-365 |
8.53e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.86 E-value: 8.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 208 GTQFPGAAVttpqapYVRPPSA--PYARTP-PQPLGShslsGNPPLTPFTAPSMPPPATFPGAPHGRPA-------VSGL 277
Cdd:PHA03247 2471 GELFPGAPV------YRRPAEArfPFAAGAaPDPGGG----GPPDPDAPPAPSRLAPAILPDEPVGEPVhprmltwIRGL 2540
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 278 PY---------GPPSAQVAPPLGFPGQMQPPRY----------------GMGPLPNQSMTNIPTAMGQPGATVPGPSRID 332
Cdd:PHA03247 2541 EElasddagdpPPPLPPAAPPAAPDRSVPPPRPaprpsepavtsrarrpDAPPQSARPRAPVDDRGDPRGPAPPSPLPPD 2620
|
170 180 190
....*....|....*....|....*....|...
gi 334187096 333 PNQIPRPGSSSSPTVFETRQSNQANPPPPATSD 365
Cdd:PHA03247 2621 THAPDPPPPSPSPAANEPDPHPPPTVPPPERPR 2653
|
|
| PBP1 |
COG5180 |
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification]; ... |
64-429 |
9.79e-05 |
|
PAB1-binding protein, interacts with poly(A)-binding protein [RNA processing and modification];
Pssm-ID: 444064 [Multi-domain] Cd Length: 548 Bit Score: 46.21 E-value: 9.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 64 SPQPFPQQSPSYGAPQRGPSPMSRPGPPAGMARPGGPPPVSQPAGF-QSNVPLNRPTGPPSRQPSFGSRPSMPGGPVAQP 142
Cdd:COG5180 139 REATSASAGVALAAALLQRSDPILAKDPDGDSASTLPPPAEKLDKVlTEPRDALKDSPEKLDRPKVEVKDEAQEEPPDLT 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 143 AASSSGFPAFGPSGSVaagpPPGSRPMAFGSPPPVGSGMSMPPSGmiggPVSNGHQMVGSggfprgtqfpgaavttpQAP 222
Cdd:COG5180 219 GGADHPRPEAASSPKV----DPPSTSEARSRPATVDAQPEMRPPA----DAKERRRAAIG-----------------DTP 273
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 223 YVRPPSAPYARTPPQPLGSHSLSGNPPLTPFTAPSMPPPATFPGAPHGRPAVSGLPYGPPSA-------QVAPPLGFPGQ 295
Cdd:COG5180 274 AAEPPGLPVLEAGSEPQSDAPEAETARPIDVKGVASAPPATRPVRPPGGARDPGTPRPGQPTerpagvpEAASDAGQPPS 353
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 296 MQPPRYGMGPL-PNQSMTNIPTAMGQPGATVPGPSRIDPNQIPRPGSSSSPTvfetrqsnQANPPPPATSDYVVRDTGNC 374
Cdd:COG5180 354 AYPPAEEAVPGkPLEQGAPRPGSSGGDGAPFQPPNGAPQPGLGRRGAPGPPM--------GAGDLVQAALDGGGRETASL 425
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 334187096 375 SP--RYMRCTINQIPCTVDLLSTSGMqLALMVQPLALSHPSEEPIQVVDfGEGGPVR 429
Cdd:COG5180 426 GGaaGGAGQGPKADFVPGDAESVSGP-AGLADQAGAAASTAMADFVAPV-TDATPVD 480
|
|
| PPE |
COG5651 |
PPE-repeat protein [Function unknown]; |
133-347 |
1.28e-04 |
|
PPE-repeat protein [Function unknown];
Pssm-ID: 444372 [Multi-domain] Cd Length: 385 Bit Score: 45.65 E-value: 1.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 133 SMPGGPVAQPAASSSGFPAFGPSGSVAAGPPPGSRPMAFGSPPPVGSGMSMPPSGMIGGPVSNGHQMVGSGGFPRGTQFP 212
Cdd:COG5651 164 LTPFTQPPPTITNPGGLLGAQNAGSGNTSSNPGFANLGLTGLNQVGIGGLNSGSGPIGLNSGPGNTGFAGTGAAAGAAAA 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 213 GAAVTTPQAPYVRPPSAPYARTPPQPLGSH-------SLSGNPPLTPFTAPSMPPPATFPGAPHGRPAVSGLPYGPPSAq 285
Cdd:COG5651 244 AAAAAAAAGAGASAALASLAATLLNASSLGlaataasSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGAAGAAGAT- 322
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 334187096 286 vAPPLGFPGQMQPPRYGMGPLPNQSMTNIPTAMGQPGATVPGPSRIDPNQIPRPGSSSSPTV 347
Cdd:COG5651 323 -GAGAALGAGAAAAAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASGGGA 383
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
59-367 |
1.75e-04 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 45.82 E-value: 1.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 59 PPF--GQSPQPFpQQSPSYGA---PQRGPSPMSRPGP----------PAGMARPGGPPPVS----QPAGFQSN----VPL 115
Cdd:PHA03379 420 VEKprPEVPQSL-ETATSHGSaqvPEPPPVHDLEPGPlhdqhsmapcPVAQLPPGPLQDLEpgdqLPGVVQDGrpacAPV 498
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 116 NRPTGP------------PSRQPSFGSRPSMPGGPVAQPAASSSGFPAFGPSGSVAAGP--PPGSRPMAfgspppvgsgM 181
Cdd:PHA03379 499 PAPAGPivrpweaslsqvPGVAFAPVMPQPMPVEPVPVPTVALERPVCPAPPLIAMQGPgeTSGIVRVR----------E 568
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 182 SMPPSGMIGGPVSNGHQMVGSGGFPRGTqfpgaavttpqaPYVRPPSAPYARTPPQplgshsLSGNPPLTPFTAPSMPPP 261
Cdd:PHA03379 569 RWRPAPWTPNPPRSPSQMSVRDRLARLR------------AEAQPYQASVEVQPPQ------LTQVSPQQPMEYPLEPEQ 630
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 262 ATFPGAPHGRPA----VSGLPYGPPSAQVAP---PLGFPGQMQPPRYGMGPLPNQSMTN---IPTAMGQPGATVPGPSRI 331
Cdd:PHA03379 631 QMFPGSPFSQVAdvmrAGGVPAMQPQYFDLPlqqPISQGAPLAPLRASMGPVPPVPATQpqyFDIPLTEPINQGASAAHF 710
|
330 340 350
....*....|....*....|....*....|....*.
gi 334187096 332 DPNQIPRPGSSSSPTVFETRQSNQANPPPPATSDYV 367
Cdd:PHA03379 711 LPQQPMEGPLVPERWMFQGATLSQSVRPGVAQSQYF 746
|
|
| PHA02682 |
PHA02682 |
ORF080 virion core protein; Provisional |
212-347 |
2.06e-04 |
|
ORF080 virion core protein; Provisional
Pssm-ID: 177464 [Multi-domain] Cd Length: 280 Bit Score: 44.47 E-value: 2.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 212 PGAAVTTPQAPYVRPPSAPYARTPPQPLgshslsgnPPLTPFTAPSMPPPATFPG----APHGRPAVSGLPYGPP----- 282
Cdd:PHA02682 86 PACAAPAPACPACAPAAPAPAVTCPAPA--------PACPPATAPTCPPPAVCPAparpAPACPPSTRQCPPAPPlptpk 157
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 334187096 283 SAQVAPPLGFPGQMQPPRYgmgplPNQSMTNIPTAmgqPGATVPGPSRIdPNQIPRPGSSSSPTV 347
Cdd:PHA02682 158 PAPAAKPIFLHNQLPPPDY-----PAASCPTIETA---PAASPVLEPRI-PDKIIDADNDDKDLI 213
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
122-372 |
2.25e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 45.47 E-value: 2.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 122 PSRQPSFGSRPSMPGGPVAQPAASSSGFPAfgpsgsVAAGPPPGSRPMAFGSPPPVGSGMSMPPSGMIGGPVSNGHQmvg 201
Cdd:PRK08691 360 PLAAASCDANAVIENTELQSPSAQTAEKET------AAKKPQPRPEAETAQTPVQTASAAAMPSEGKTAGPVSNQEN--- 430
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 202 SGGFPRGTQfPGAAVT---TPQAPYVRPPSAPYARTPPQPLGSHSLSGNPPlTPFTAPSMPPPATFPGAPHGRPAVSGLP 278
Cdd:PRK08691 431 NDVPPWEDA-PDEAQTaagTAQTSAKSIQTASEAETPPENQVSKNKAADNE-TDAPLSEVPSENPIQATPNDEAVETETF 508
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 279 YGPPSAQVAPPLGFPGQMQPPRygmgplpnqsmtniptamgqPGATVPGP--SRIDPNQIPRPGSSSSPTVFETRQSNQA 356
Cdd:PRK08691 509 AHEAPAEPFYGYGFPDNDCPPE--------------------DGAEIPPPdwEHAAPADTAGGGADEEAEAGGIGGNNTP 568
|
250 260
....*....|....*....|
gi 334187096 357 NPPPPATSD----YVVRDTG 372
Cdd:PRK08691 569 SAPPPEFSTenwaAIVRHFA 588
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
117-364 |
2.48e-04 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 45.43 E-value: 2.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 117 RPTGPPSRQPSFGSRPSMPGGPVAQPAASSSGFPAFGPSGSVAAGPPPGSRPMAfgsPPPVGsgmSMPPSGMigGPVSNG 196
Cdd:PHA03379 410 EPTYGTPRPPVEKPRPEVPQSLETATSHGSAQVPEPPPVHDLEPGPLHDQHSMA---PCPVA---QLPPGPL--QDLEPG 481
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 197 HQMVGSGGFPRGTQFPgaaVTTPQAPYVRPPSAPYARTPPQPLGSHS---LSGNP---PLTPFTAPSMPPPA----TFPG 266
Cdd:PHA03379 482 DQLPGVVQDGRPACAP---VPAPAGPIVRPWEASLSQVPGVAFAPVMpqpMPVEPvpvPTVALERPVCPAPPliamQGPG 558
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 267 APHGRPAVSgLPYGPPS---AQVAPPLGFPGQMQPPRYGMGPLPNQSMTNI-PTAMGQPGATVPGPSRIDPNQIPRPGSS 342
Cdd:PHA03379 559 ETSGIVRVR-ERWRPAPwtpNPPRSPSQMSVRDRLARLRAEAQPYQASVEVqPPQLTQVSPQQPMEYPLEPEQQMFPGSP 637
|
250 260
....*....|....*....|..
gi 334187096 343 SSPTVFETRQSNQANPPPPATS 364
Cdd:PHA03379 638 FSQVADVMRAGGVPAMQPQYFD 659
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
70-182 |
2.66e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 45.31 E-value: 2.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 70 QQSPSYGAPQRGPSPMSRPGPPAGMARPGGPPPVSQPAGFQSnvplnrPTGPPSRQPsfgSRPSMPGGPVAQPAASSSGF 149
Cdd:PHA03247 404 QTRPAAPVPASVPTPAPTPVPASAPPPPATPLPSAEPGSDDG------PAPPPERQP---PAPATEPAPDDPDDATRKAL 474
|
90 100 110
....*....|....*....|....*....|...
gi 334187096 150 PAFGPSGSvaAGPPPGSRPMAFGSPPPVGSGMS 182
Cdd:PHA03247 475 DALRERRP--PEPPGADLAELLGRHPDTAGTVV 505
|
|
| Gag_spuma |
pfam03276 |
Spumavirus gag protein; |
165-337 |
2.85e-04 |
|
Spumavirus gag protein;
Pssm-ID: 460872 [Multi-domain] Cd Length: 614 Bit Score: 44.74 E-value: 2.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 165 GSRPMAFGSPPPVGSGMSMPPSGMIGGPvsnghqmvgsggfprgtqfpgaAVTTPQAPYVRPPSAPYARTPPQPLGSHSL 244
Cdd:pfam03276 177 EISPGAQGGIPPGASFSGLPSLPAIGGI----------------------HLPAIPGIHARAPPGNIARSLGDDIMPSLG 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 245 SGNPPLTPFTAPSMPPPATFPGAP------HGRPAVSGLPYGPPSAQVAPPLGFPGQMQPPRYGMGPLPNQSMTNIPtam 318
Cdd:pfam03276 235 DAGMPQPRFAFHPGNPFAEAEGHPfaeaegERPRDIPRAPRIDAPSAPAIPAIQPIAPPMIPPIGAPIPIPHGASIP--- 311
|
170
....*....|....*....
gi 334187096 319 GQPGATVPGPSRIDPNQIP 337
Cdd:pfam03276 312 GEHIRNPREEPIRLGREAP 330
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
3-366 |
3.05e-04 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 45.04 E-value: 3.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 3 APVPPGAPRPNSQQNSGPPNFYPGSQGNSNALADNMQNLSLNRPPPMMPGSGPRPPPPFGQSPQpfPQQSPSYGAPQRGP 82
Cdd:PHA03377 535 KVQDGFQRSGRRQKRATPPKVSPSDRGPPKASPPVMAPPSTGPRVMATPSTGPRDMAPPSTGPR--QQAKCKDGPPASGP 612
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 83 ----SPMSRPGPPAG-----------MARPGGPPPVS--------------QPAGFQSNVPLNRPTGPPSRQPSFGSRPS 133
Cdd:PHA03377 613 hekqPPSSAPRDMAPsvvrmflrerlLEQSTGPKPKSfwemragrdgsgiqQEPSSRRQPATQSTPPRPSWLPSVFVLPS 692
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 134 MPGGPvAQPAASSSGFPAFGPSGSVAAGPPPGSRPMA--------FGSPPPvgsgmsmPPSGMIGGPVSNGHQMVGSGGF 205
Cdd:PHA03377 693 VDAGR-AQPSEESHLSSMSPTQPISHEEQPRYEDPDDpldlslhpDQAPPP-------SHQAPYSGHEEPQAQQAPYPGY 764
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 206 --PRGTQFPGAAVTTPQAPYVRPPS-----APYARTPPQPLGSHSLS-------GNPPLTPFTA-PSMPPPATFPGAPHG 270
Cdd:PHA03377 765 wePRPPQAPYLGYQEPQAQGVQVSSypgyaGPWGLRAQHPRYRHSWAywsqypgHGHPQGPWAPrPPHLPPQWDGSAGHG 844
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 271 RPAVSGLPygPPSAQVAPPLgfPGQMQPPRYgMGPLPNQSMTNIPTAMGQPGATV-PGPSRIDPNQIPRPGSSSSptvfE 349
Cdd:PHA03377 845 QDQVSQFP--HLQSETGPPR--LQLSQVPQL-PYSQTLVSSSAPSWSSPQPRAPIrPIPTRFPPPPMPLQDSMAV----G 915
|
410
....*....|....*..
gi 334187096 350 TRQSNQANPPPPATSDY 366
Cdd:PHA03377 916 CDSSGTACPSMPFASDY 932
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
97-364 |
3.37e-04 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 44.66 E-value: 3.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 97 PGGPPPVSQPAGFQSNVPLNRPTGPPsrQPSFGSRPSMPGGPV-------AQPAASSSGFPAFGPSGSVAAGPP---PGS 166
Cdd:PHA03377 395 PNMEPVQQRPVMFVSRVPWRKPRTLP--WPTPKTHPVKRTLVKtsgrsdeAEQAQSTPERPGPSDQPSVPVEPAhltPVE 472
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 167 RPMAF-----GSPPPVGSGMSMPPSGMIGGP---------------VSNGHQMVGSGGFPRGTQFPGAAVT-TPQAPYVR 225
Cdd:PHA03377 473 HTTVIlhqppQSPPTVAIKPAPPPSRRRRGAcvvydddiievidveTTEEEESVTQPAKPHRKVQDGFQRSgRRQKRATP 552
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 226 PPSAPYARTPP---QPLGSHSLSGNPPLTPftaPSMPPPATFPGAPHGRpAVSGLPYGPPSA---QVAPPLGFPGQMQPP 299
Cdd:PHA03377 553 PKVSPSDRGPPkasPPVMAPPSTGPRVMAT---PSTGPRDMAPPSTGPR-QQAKCKDGPPASgphEKQPPSSAPRDMAPS 628
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 334187096 300 RYGM-----------GPLPnQSMTNIPTAMGQPGATVPGPSRIDPN-QIPRPGSSSSPTVFETRQSNQANPPPPATS 364
Cdd:PHA03377 629 VVRMflrerlleqstGPKP-KSFWEMRAGRDGSGIQQEPSSRRQPAtQSTPPRPSWLPSVFVLPSVDAGRAQPSEES 704
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
63-172 |
4.02e-04 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 44.41 E-value: 4.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 63 QSPQPFPQQsPSYGAPQ---RGP--------------SPMSRPGPPAGMARPGGPPPVSQ---PAGFQSNVPLNRPTGPP 122
Cdd:TIGR01628 384 QLPMGSPMG-GAMGQPPyygQGPqqqfngqplgwprmSMMPTPMGPGGPLRPNGLAPMNAvraPSRNAQNAAQKPPMQPV 462
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 334187096 123 SRQPSFGSRPSMPGGPVAQPAASSSGfpAFGPSGSVAAGPPPGSRPMAFG 172
Cdd:TIGR01628 463 MYPPNYQSLPLSQDLPQPQSTASQGG--QNKKLAQVLASATPQMQKQVLG 510
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
67-194 |
4.81e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 44.29 E-value: 4.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 67 PFPQQSPSyGAPQRGPSPMSRPGPPAGMARPGGPPPVSQPAGFQSNVPLNRPTG-PPSRQPSFGSRPSMPGGPVAqPAAS 145
Cdd:PRK14959 367 PVESLRPS-GGGASAPSGSAAEGPASGGAATIPTPGTQGPQGTAPAAGMTPSSAaPATPAPSAAPSPRVPWDDAP-PAPP 444
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 334187096 146 SSGFPAFGPSGSVAAGPPPGsRPMAFGSP---PPVGSGMSMPPSGMIGGPVS 194
Cdd:PRK14959 445 RSGIPPRPAPRMPEASPVPG-APDSVASAsdaPPTLGDPSDTAEHTPSGPRT 495
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
64-185 |
7.04e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.01 E-value: 7.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 64 SPQPFPQQSPSYGAPQRGPSPMSRPGPPAGMARPggPPPVSQPAGFQSNVPLN-RPTGPPSRQPSFGSRPSMPGGPVAQP 142
Cdd:PHA03307 812 ASRTASKRKSRSHTPDGGSESSGPARPPGAAARP--PPARSSESSKSKPAAAGgRARGKNGRRRPRPPEPRARPGAAAPP 889
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 334187096 143 AASSSGFPAFGPSGSVAAGPPPGSRPMAFGSPPPVGSGMSMPP 185
Cdd:PHA03307 890 KAAAAAPPAGAPAPRPRPAPRVKLGPMPPGGPDPRGGFRRVPP 932
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
83-361 |
9.72e-04 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 43.02 E-value: 9.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 83 SPMSRPGPPAGMA-RPGGPPPVSQPAGFQSNVPlNRPTGPPSRQPSF--GSRPSMPG--GPVAQPAASSSGFPAFGPSGS 157
Cdd:pfam17823 99 EPATREGAADGAAsRALAAAASSSPSSAAQSLP-AAIAALPSEAFSAprAAACRANAsaAPRAAIAAASAPHAASPAPRT 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 158 VAAGPPPGSRPMAFGSPPPVGSGMS----MPPSGMIGGPVSNGHQMVGSGGFPRGTQFPGAAVTTPQAPYVRPPS----A 229
Cdd:pfam17823 178 AASSTTAASSTTAASSAPTTAASSApatlTPARGISTAATATGHPAAGTALAAVGNSSPAAGTVTAAVGTVTPAAlatlA 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 230 PYARTPPQPLGSHSLSGNPPLTPFTAPSMPPPATFPG-APHGRPAVSGlpygpPSAQVA---PPLGFPGQMQPPRYGMGP 305
Cdd:pfam17823 258 AAAGTVASAAGTINMGDPHARRLSPAKHMPSDTMARNpAAPMGAQAQG-----PIIQVStdqPVHNTAGEPTPSPSNTTL 332
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 334187096 306 LPNQSMTNIPTAMGQPGATVPGPSRIDPNQIPRPGSSSSPTVFETRQSNQANPPPP 361
Cdd:pfam17823 333 EPNTPKSVASTNLAVVTTTKAQAKEPSASPVPVLHTSMIPEVEATSPTTQPSPLLP 388
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
67-364 |
1.02e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 43.37 E-value: 1.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 67 PFPQQSPSYGAPQRGPSPMSRPGPPAGM--ARPGGPPPVSQPAGFQSNVP-LNRPTGPPSRQPSFGSRPSmPGGPVAQPA 143
Cdd:pfam05109 455 PTNLTAPASTGPTVSTADVTSPTPAGTTsgASPVTPSPSPRDNGTESKAPdMTSPTSAVTTPTPNATSPT-PAVTTPTPN 533
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 144 ASSSGFPAFGPSGSVAAGPPPGSRPM-AFGSPPPVGSGMSM---PPSGMIGGPVSNGHQmvgsggfprgtqfPGAAVTTP 219
Cdd:pfam05109 534 ATSPTLGKTSPTSAVTTPTPNATSPTpAVTTPTPNATIPTLgktSPTSAVTTPTPNATS-------------PTVGETSP 600
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 220 QAPYVR-----PPSAPYARTPPQPLGSHSLSGNPPLTPFTAPSMPPpatfpgaphgRPAVSGLPYGPPSAQVAPplgfpg 294
Cdd:pfam05109 601 QANTTNhtlggTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSMSL----------RPSSISETLSPSTSDNST------ 664
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 334187096 295 QMQPPRYGMGPLPNQSMTNI---PTAMGQPGATVPGPSRIDPNQIPRPGSSSSPTVFETRQSNQANPPPPATS 364
Cdd:pfam05109 665 SHMPLLTSAHPTGGENITQVtpaSTSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGEVNVTKGTPPKNATS 737
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
212-333 |
1.06e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 43.16 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 212 PGAAVTTPQ----APYVRPPSAPYARTPPQPLGSHSLSGNPPLTPFTAPSMPPPATFPGAPHGRPAVSGLPYGPPSAQVA 287
Cdd:PRK14951 366 PAAAAEAAApaekKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAV 445
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 334187096 288 PPLGFPGQMQPPRYGMGPLPNQSMTNIPTAmGQPGATVPGPSRIDP 333
Cdd:PRK14951 446 ALAPAPPAQAAPETVAIPVRVAPEPAVASA-APAPAAAPAAARLTP 490
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
126-274 |
1.14e-03 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 42.45 E-value: 1.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 126 PSFGsRPSMPGGPVAQPAASSSGFPAFGPSGSVAAGPPPGSRPmafgSPPPVGSGMSMPPSGmigGPVSNGHQMVGSGGF 205
Cdd:NF040712 190 PDFG-RPLRPLATVPRLAREPADARPEEVEPAPAAEGAPATDS----DPAEAGTPDDLASAR---RRRAGVEQPEDEPVG 261
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 334187096 206 PRGTQFPGAAVTTPQAPYVRPPSAPYARTPPQPLGSHSLSGNPPLTPF---TAPSMPPPATFPGAPHGRPAV 274
Cdd:NF040712 262 PGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPAPAPAAPAAPAAPEaeePARPEPPPAPKPKRRRRRASV 333
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
151-326 |
1.19e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 42.78 E-value: 1.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 151 AFGPSGSVAAGPPPGSRPMAFGSPPPVGSGmsmppsgmiggpvsnghqmvgsggfPRGTQFPGAAVTTPQAPYVRPPSAP 230
Cdd:PRK14951 363 AFKPAAAAEAAAPAEKKTPARPEAAAPAAA-------------------------PVAQAAAAPAPAAAPAAAASAPAAP 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 231 YARTPPQPLGShslsgnPPLTPFTAPSMPPPATFPGAPHGRPAVSGLPYGPPsAQVAPPlgfPGQMQPPRYGMGPLPNQS 310
Cdd:PRK14951 418 PAAAPPAPVAA------PAAAAPAAAPAAAPAAVALAPAPPAQAAPETVAIP-VRVAPE---PAVASAAPAPAAAPAAAR 487
|
170
....*....|....*..
gi 334187096 311 MTniPTAMGQP-GATVP 326
Cdd:PRK14951 488 LT--PTEEGDVwHATVQ 502
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
249-373 |
1.37e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 42.55 E-value: 1.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 249 PLTPFTAPSMPPPATFPGAPHGRPAVSGLPYGPPSAQVAPPLGFPGQMQPPRYGMGPLPNQSMTNIPTAMGQPGATVPGP 328
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKK 440
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 334187096 329 SRIDPNQIPRPGSSSSPTVFETRQSNQANPPPPATSDYVVRDTGN 373
Cdd:PRK07994 441 SEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATN 485
|
|
| EP400_N |
pfam15790 |
E1A-binding protein p400, N-terminal; EP400_N is a family of eukaryote proteins. the exact ... |
65-252 |
1.51e-03 |
|
E1A-binding protein p400, N-terminal; EP400_N is a family of eukaryote proteins. the exact function of this domain is not known. This family is largely low-complexity residues.
Pssm-ID: 434938 [Multi-domain] Cd Length: 489 Bit Score: 42.29 E-value: 1.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 65 PQPFPQQSPSygapqrgpspMSRPGPPAGMARPGGPPPV-----SQPAGFQSNVPLNRP-----------------TGPP 122
Cdd:pfam15790 129 PQQVQPQSPT----------QHSPVPLQGVQRPGAPGTGlgvcgQSPTRFVDASMLVRQislgspsggghfvyqdgTGLA 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 123 SRQPSFGS-RPSMPGGP-------VAQPAASSSG-FPAFGPSGSVAAgpppGSRPMAFGSPPPVGSGmSMPP--SGMIGG 191
Cdd:pfam15790 199 QIAPGAGQvQLASPGTPgsvrerrLSQPHSQTGGtIHHLGPQSPAAA----GAGLQTLGSPGHITTS-NLPPqiSSIIQG 273
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 334187096 192 pvsnghQMVGSGGFPRGTQFPGAAVTTPQA----PYVRPPSAPYARTPPQPLGShslsgnPPLTP 252
Cdd:pfam15790 274 ------QLARPLGFEKTAQVVVAGAGGPAAsfgiPSSIPPTSPSRTSPPPGLSS------NPLTS 326
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
118-274 |
1.63e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 42.67 E-value: 1.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 118 PTGPPSRQPSFGSRPSMPGGPVAQPAASSSGfPAFGPSGSVAAGPPPGSRPMAFGSPPPVGSGMSMPPSgmiggpvsngh 197
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAAAPAAAPAPAAAA-PAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGA----------- 453
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 334187096 198 qmvgsggfprGTQFPGAAVTTPQAPYVRPPSAPYARTPPQPLGSHSlsgnppltPFTAPSMPPPATFPGAPHGRPAV 274
Cdd:PRK07764 454 ----------PSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPA--------PAAAPAAPAAPAAPAGADDAATL 512
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
167-377 |
2.25e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 42.17 E-value: 2.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 167 RPMAFgspPPVGSGMSMPPSGMIGGPVSNGhqmvgsggfPRGTQFPGAAVTTPQAPYVRPPSAPYARTPPQPLGSHSLSG 246
Cdd:PRK12323 359 RMLAF---RPGQSGGGAGPATAAAAPVAQP---------APAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARR 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 247 NPPLTPFTAPSMPPPATFPGAPhgRPAvsglpygpPSAQVAPPLGFPGQMQPPRYGMGPLPNQSMTNIPTAMGQPGAT-- 324
Cdd:PRK12323 427 SPAPEALAAARQASARGPGGAP--APA--------PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDdp 496
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 334187096 325 -----------VPGPSRIDP-------NQIPRPGSSSSPTVFETRQSNQANPPPPATSDYVVRDTGNCSPR 377
Cdd:PRK12323 497 ppweelppefaSPAPAQPDAapagwvaESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPR 567
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
132-277 |
2.98e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.51 E-value: 2.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 132 PSMPGGPVAQPAASSSGFPAFGPSGSVAAGPPPGSRPmafGSPPPVGSGMSMPPSGMIGGPVSNGhqmvgsggfPRGTQF 211
Cdd:PRK07764 390 GAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPA---AAPQPAPAPAPAPAPPSPAGNAPAG---------GAPSPP 457
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 334187096 212 PGAAVTTPQAPYVRPPSAPYARTPPQPLGSHSlsgnppltPFTAPSMPPPatfPGAPHGRPAVSGL 277
Cdd:PRK07764 458 PAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPA--------PAAAPAAPAA---PAAPAGADDAATL 512
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
73-239 |
3.25e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 41.62 E-value: 3.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 73 PSYGAPQRGPSPMSRPgppagmARPGGPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSMPGGPVAQPAASSSgfPAF 152
Cdd:PRK14951 366 PAAAAEAAAPAEKKTP------ARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAP--AAA 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 153 GPSGSVAAGPPPgsrpmaFGSPPPVGSGMSMPPSgmiggpvsnghqmvgsggfprgTQFPGAAVTTPQAPYVRPPSAPYA 232
Cdd:PRK14951 438 PAAAPAAVALAP------APPAQAAPETVAIPVR----------------------VAPEPAVASAAPAPAAAPAAARLT 489
|
....*..
gi 334187096 233 RTPPQPL 239
Cdd:PRK14951 490 PTEEGDV 496
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
233-370 |
3.54e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.51 E-value: 3.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 233 RTPPQPLGSHSLSGNPPLTPFTAPSMPPPATFPGAPHGRPAVSGLPygPPSAQVAPPLGFPGQMQPPRYGMGPLPNQSmt 312
Cdd:PRK07764 384 RLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAP--QPAPAPAPAPAPPSPAGNAPAGGAPSPPPA-- 459
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 334187096 313 niPTAMGQPGATVPGPSRIDPNQIPRPGSSSSPTVfETRQSNQANPPPPATSDYVVRD 370
Cdd:PRK07764 460 --AAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAA-APAAPAAPAAPAGADDAATLRE 514
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
119-361 |
3.71e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 41.61 E-value: 3.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 119 TGPPSRQPSFGS-RPSMPGGPVAQPAASSSGFPAFGPSGSVAAGPPPGSRPMAFGSPPPVGSGMSMPPsgmIGGPvSNGH 197
Cdd:PRK10263 295 SGNRATQPEYDEyDPLLNGAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQPTVAWQP---VPGP-QTGE 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 198 QMVGSGgfPRGTQfPGAAVTTPQAPYVRPPSAPYartPPQPLGSHSLSGNPPLTPFTAPSMPPPATFPGaphgrpavsgl 277
Cdd:PRK10263 371 PVIAPA--PEGYP-QQSQYAQPAVQYNEPLQQPV---QPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPY----------- 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 278 pygPPSAQVAPPLGFPGQMQPPRYGMGPLPNQsmtniptamgQPGATVPGPSRIDPNQIPRPGSSSSPTVFETRQSNQAN 357
Cdd:PRK10263 434 ---YAPAPEQPVAGNAWQAEEQQSTFAPQSTY----------QTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETK 500
|
....
gi 334187096 358 PPPP 361
Cdd:PRK10263 501 PARP 504
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
135-289 |
4.33e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.12 E-value: 4.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 135 PGGPVAQPAASSSGFPAFGPSGSVAAGPPPGSRPMAFGSPPPVGSGmsmppsgmiggpvsnghqmvgsggfprgTQFPGA 214
Cdd:PRK07764 371 ERGLLARLERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAA----------------------------PAAAAA 422
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 334187096 215 AVTTPQAPYVRPPSAPYARTPPQPLGSHSLSGNPPLTPFTAPSMPPPATFPGAPHGRPAVSGLPYGPPSAQVAPP 289
Cdd:PRK07764 423 PAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAP 497
|
|
| Pro-rich |
pfam15240 |
Proline-rich protein; This family includes several eukaryotic proline-rich proteins. |
219-345 |
5.25e-03 |
|
Proline-rich protein; This family includes several eukaryotic proline-rich proteins.
Pssm-ID: 464580 [Multi-domain] Cd Length: 167 Bit Score: 38.87 E-value: 5.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 219 PQAPYVRPPSAPYARTPPQPLGSHSLSGNPPLTpftAPSMPPPATFPGAPHGRPAVSGLPYGPPSAQVAPPLGFPGQMQP 298
Cdd:pfam15240 39 SQQGGQGPQGPPPGGFPPQPPASDDPPGPPPPG---GPQQPPPQGGKQKPQGPPPQGGPRPPPGKPQGPPPQGGNQQQGP 115
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 334187096 299 PRYGMGPLPNQSMTNIPTAMG---QPGATVPGPSRIDPNQIPRPGSSSSP 345
Cdd:pfam15240 116 PPPGKPQGPPPQGGGPPPQGGnqqGPPPPPPGNPQGPPQRPPQPGNPQGP 165
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
4-177 |
5.41e-03 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 40.74 E-value: 5.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 4 PVPPGAPRPNSQQNSGPPNFYPGSQGNS-NALADNMQNLSLNRPPPMMPGSGPRPPPPFGQSPQPFP---QQSPSYGAPQ 79
Cdd:PRK12727 63 PATAAAPAPAPQAPTKPAAPVHAPLKLSaNANMSQRQRVASAAEDMIAAMALRQPVSVPRQAPAAAPvraASIPSPAAQA 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 80 RGPSPMSRPGPPAGMARPGGPPPVSqpAGFQSNVPLNRPTGPPSRQPSFGSRPSMPG-GPVAQPAASSSGFPAFGPSGSV 158
Cdd:PRK12727 143 LAHAAAVRTAPRQEHALSAVPEQLF--ADFLTTAPVPRAPVQAPVVAAPAPVPAIAAaLAAHAAYAQDDDEQLDDDGFDL 220
|
170
....*....|....*....
gi 334187096 159 AAGPPPGSRPMAFgsPPPV 177
Cdd:PRK12727 221 DDALPQILPPAAL--PPIV 237
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
64-178 |
5.57e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 40.85 E-value: 5.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 64 SPQPFPQQSPSYGAPQRGPSPMSRPGPPAGMARPGGPPPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSMPGGPVAQPA 143
Cdd:PRK14951 380 TPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPET 459
|
90 100 110
....*....|....*....|....*....|....*
gi 334187096 144 ASSSGFPAFGPSGSVAAGPPPGSRPMAFGSPPPVG 178
Cdd:PRK14951 460 VAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEG 494
|
|
| Cytadhesin_P30 |
pfam07271 |
Cytadhesin P30/P32; This family consists of several Mycoplasma species specific Cytadhesin P32 ... |
63-187 |
5.92e-03 |
|
Cytadhesin P30/P32; This family consists of several Mycoplasma species specific Cytadhesin P32 and P30 proteins. P30 has been found to be membrane associated and localized on the tip organelle. It is thought that it is important in cytadherence and virulence. The N-terminus contains two predicted transmembrane helices followed by a long region of a short 6 residue proline rich repeat.
Pssm-ID: 429374 [Multi-domain] Cd Length: 275 Bit Score: 39.95 E-value: 5.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 63 QSPQPFPQQSPSYGAPQRGPSPMSRPGPP--AGMA-RPGGP-----PPVSQPAGFQSNVPLNRPTGPPSRQPSFGSRPSM 134
Cdd:pfam07271 144 VANQPQMGINQPQINPQFGPNPQQRIGFPmqPNMGmRPGFNqmpgmPPNQMRPGFNQMPGMPPRPGFPNPMPNMQPRPGF 223
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 334187096 135 PGGPVAQPAASSSGFPAFGPSGSVAAGPPPGSRPMAFGSPPPVGsgmsMPPSG 187
Cdd:pfam07271 224 RPQPGPMGNRPGGGFPHPGTPMGPNRMPNPGMNQRPGMAPPRPG----FPPQN 272
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
61-271 |
7.97e-03 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 40.19 E-value: 7.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 61 FGQSPQpfpqqspsygAPQRGPSPMSRPGPPAGMARPGGPPPVSQpagfqsnVPLNRPTGP---PSRQPSFGSRPSMPGG 137
Cdd:PRK14086 104 RTSEPE----------LPRPGRRPYEGYGGPRADDRPPGLPRQDQ-------LPTARPAYPayqQRPEPGAWPRAADDYG 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 334187096 138 PVAQPAasssGFPAFGPSGSVAAGPPPGSRpmaFGSPPPVGSGMSMPPSgmiggpvsnghqmvGSGGFPRGTQFPGAAVT 217
Cdd:PRK14086 167 WQQQRL----GFPPRAPYASPASYAPEQER---DREPYDAGRPEYDQRR--------------RDYDHPRPDWDRPRRDR 225
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 334187096 218 TPQaPYVRPPSAPYARTPPQPLGSHSLSGNP--PLTPFTAPSMPPPATFPGAPHGR 271
Cdd:PRK14086 226 TDR-PEPPPGAGHVHRGGPGPPERDDAPVVPirPSAPGPLAAQPAPAPGPGEPTAR 280
|
|
| |
