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Conserved domains on  [gi|161077047|ref|NP_001097302|]
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uncharacterized protein Dmel_CG33156, isoform F [Drosophila melanogaster]

Protein Classification

diacylglycerol kinase catalytic domain-containing protein( domain architecture ID 546)

diacylglycerol kinase catalytic domain-containing protein is involved in the conversion of diacylglycerol (DAG) to phosphatidic acid (PA), utilizing ATP as a source of the phosphate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DAGK_cat super family cl01255
Diacylglycerol kinase catalytic domain; Diacylglycerol (DAG) is a second messenger that acts ...
 93-421 2.69e-101

Diacylglycerol kinase catalytic domain; Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. The catalytic domain is assumed from the finding of bacterial homologs. YegS is the Escherichia coli protein in this family whose crystal structure reveals an active site in the inter-domain cleft formed by four conserved sequence motifs, revealing a novel metal-binding site. The residues of this site are conserved across the family.


The actual alignment was detected with superfamily member PLN02935:

Pssm-ID: 445337 [Multi-domain]  Cd Length: 508  Bit Score: 311.77  E-value: 2.69e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047  93 LTWYKPPLTVLVIKKVSDASVLAPFVYLVDWLLQEKNMVVWVESAVLEDVqLNENVRFKAIRdklvTFKDGRDDLT--DR 170
Cdd:PLN02935 188 LKWESDPQTVLIITKPNSTSVRVLCAEMVRWLREQKGLNIYVEPRVKKEL-LSESSYFNFVQ----TWEDEKEILLlhTK 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 171 IDFIVCLGGDGTLLYASLLFQQSVPPVMAFHLGSLGFLTPFRFDNFEEQLTSVLEGHAALTLRSRLRCVMhRRSDRKHEA 250
Cdd:PLN02935 263 VDLVITLGGDGTVLWAASMFKGPVPPVVPFSMGSLGFMTPFHSEQYRDCLDAILKGPISITLRHRLQCHI-IRDAAKNEY 341

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 251 KTLEadldgearpaanSILVLNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVPA 330
Cdd:PLN02935 342 ETEE------------PILVLNEVTIDRGISSFLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPG 409

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 331 IMVTPICPHSLSFRPIVVPAGVELKISVSPESRNTSWVSFDGRNRQELFHGDSLRVTTSIYPVPCICAQDQISDWFASLA 410
Cdd:PLN02935 410 ILFTPICPHSLSFRPLILPEYVTIRVQVPFNSRGQAWASFDGKDRKQLSAGDALVCSMAPWPVPTACQVESTNDFLRSIH 489

                        330
                 ....*....|.
gi 161077047 411 DGLHWNVRKRQ 421
Cdd:PLN02935 490 DGLHWNLRKTQ 500
 
Name Accession Description Interval E-value
PLN02935 PLN02935
Bifunctional NADH kinase/NAD(+) kinase
 93-421 2.69e-101

Bifunctional NADH kinase/NAD(+) kinase


Pssm-ID: 215505 [Multi-domain]  Cd Length: 508  Bit Score: 311.77  E-value: 2.69e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047  93 LTWYKPPLTVLVIKKVSDASVLAPFVYLVDWLLQEKNMVVWVESAVLEDVqLNENVRFKAIRdklvTFKDGRDDLT--DR 170
Cdd:PLN02935 188 LKWESDPQTVLIITKPNSTSVRVLCAEMVRWLREQKGLNIYVEPRVKKEL-LSESSYFNFVQ----TWEDEKEILLlhTK 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 171 IDFIVCLGGDGTLLYASLLFQQSVPPVMAFHLGSLGFLTPFRFDNFEEQLTSVLEGHAALTLRSRLRCVMhRRSDRKHEA 250
Cdd:PLN02935 263 VDLVITLGGDGTVLWAASMFKGPVPPVVPFSMGSLGFMTPFHSEQYRDCLDAILKGPISITLRHRLQCHI-IRDAAKNEY 341

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 251 KTLEadldgearpaanSILVLNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVPA 330
Cdd:PLN02935 342 ETEE------------PILVLNEVTIDRGISSFLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPG 409

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 331 IMVTPICPHSLSFRPIVVPAGVELKISVSPESRNTSWVSFDGRNRQELFHGDSLRVTTSIYPVPCICAQDQISDWFASLA 410
Cdd:PLN02935 410 ILFTPICPHSLSFRPLILPEYVTIRVQVPFNSRGQAWASFDGKDRKQLSAGDALVCSMAPWPVPTACQVESTNDFLRSIH 489

                        330
                 ....*....|.
gi 161077047 411 DGLHWNVRKRQ 421
Cdd:PLN02935 490 DGLHWNLRKTQ 500
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
101-418 7.03e-53

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 178.79  E-value: 7.03e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 101 TVLVIKKVSDASVLAPFVYLVDWLlQEKNMVVWVESAVLEDVqlnenvrfkairdklvtfkDGRDDLTDRIDFIVCLGGD 180
Cdd:COG0061    3 RIAIVAKPGKPEALEAAEELAELL-EERGIEVVLDEDTAVPG-------------------VPLEELGEEADLVIVLGGD 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 181 GTLLYASLLFQQSVPPVMAFHLGSLGFLTPFRFDNFEEQLTSVLEGHAALTLRSRLRCVMHRRSDRKHEAktleadldge 260
Cdd:COG0061   63 GTLLRAARLLAPLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATVDRDGEVVHEA---------- 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 261 arpaansiLVLNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTgstayaaaagasMIHPSVPAIMVTPICPHS 340
Cdd:COG0061  133 --------LALNEVVVLRGSIARMIELEVYIDGEFLEEFRGDGLIVSTPTgstaynlsaggpIVHPGLDALVLTPIAPHT 204

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 161077047 341 LSFRPIVVPAGVELKISVSPESRNTSwVSFDGRNRQELFHGDSLRVTTSiyPVPCICAQDQISDWFASLADGLHWNVR 418
Cdd:COG0061  205 LSSRPLVLPDDSEIEIEVLEDSRPAV-LVADGQEVRDLEPGDRVEIRRS--PKPVRLLRLKDHSFFERLREKLGWGGD 279
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 271-396 3.07e-29

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 110.85  E-value: 3.07e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047  271 LNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVPAIMVTPICPHSLSFRPIVVPA 350
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPHSLSSRPIVVSS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 161077047  351 gvELKISVSPESRNTSWVSFDGRNRQELFHGDSLRVTTSIYPVPCI 396
Cdd:pfam20143  81 --SSKLRIRVLSRAEALLVDDGDPELDISPGDRVRVRKSYYKAKFI 124
 
Name Accession Description Interval E-value
PLN02935 PLN02935
Bifunctional NADH kinase/NAD(+) kinase
 93-421 2.69e-101

Bifunctional NADH kinase/NAD(+) kinase


Pssm-ID: 215505 [Multi-domain]  Cd Length: 508  Bit Score: 311.77  E-value: 2.69e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047  93 LTWYKPPLTVLVIKKVSDASVLAPFVYLVDWLLQEKNMVVWVESAVLEDVqLNENVRFKAIRdklvTFKDGRDDLT--DR 170
Cdd:PLN02935 188 LKWESDPQTVLIITKPNSTSVRVLCAEMVRWLREQKGLNIYVEPRVKKEL-LSESSYFNFVQ----TWEDEKEILLlhTK 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 171 IDFIVCLGGDGTLLYASLLFQQSVPPVMAFHLGSLGFLTPFRFDNFEEQLTSVLEGHAALTLRSRLRCVMhRRSDRKHEA 250
Cdd:PLN02935 263 VDLVITLGGDGTVLWAASMFKGPVPPVVPFSMGSLGFMTPFHSEQYRDCLDAILKGPISITLRHRLQCHI-IRDAAKNEY 341

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 251 KTLEadldgearpaanSILVLNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVPA 330
Cdd:PLN02935 342 ETEE------------PILVLNEVTIDRGISSFLTNLECYCDNSFVTCVQGDGLILSTTSGSTAYSLAAGGSMVHPQVPG 409

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 331 IMVTPICPHSLSFRPIVVPAGVELKISVSPESRNTSWVSFDGRNRQELFHGDSLRVTTSIYPVPCICAQDQISDWFASLA 410
Cdd:PLN02935 410 ILFTPICPHSLSFRPLILPEYVTIRVQVPFNSRGQAWASFDGKDRKQLSAGDALVCSMAPWPVPTACQVESTNDFLRSIH 489

                        330
                 ....*....|.
gi 161077047 411 DGLHWNVRKRQ 421
Cdd:PLN02935 490 DGLHWNLRKTQ 500
PLN02727 PLN02727
NAD kinase
 91-424 8.05e-84

NAD kinase


Pssm-ID: 215386 [Multi-domain]  Cd Length: 986  Bit Score: 277.15  E-value: 8.05e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047  91 QRLTWYKPPLTVLVIKKVSD-----ASVLAPFVYlvdwllQEKNMVVWVESAVlEDVqlnenvrFKAIRDK--LVTF-KD 162
Cdd:PLN02727 670 QMLMWKSTPKTVLLLKKLGQelmeeAKEVASFLY------HQEKMNVLVEPDV-HDI-------FARIPGFgfVQTFySQ 735

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 163 GRDDLTDRIDFIVCLGGDGTLLYASLLFQQSVPPVMAFHLGSLGFLTPFRFDNFEEQLTSVLEGHAAL-----TLRSRLR 237
Cdd:PLN02727 736 DTSDLHERVDFVACLGGDGVILHASNLFRGAVPPVVSFNLGSLGFLTSHYFEDFRQDLRQVIHGNNTLdgvyiTLRMRLR 815

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 238 CVMHRrsdrkheaktleadlDGEARPaANSILVLNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAA 317
Cdd:PLN02727 816 CEIFR---------------NGKAMP-GKVFDVLNEVVVDRGSNPYLSKIECYEHDRLITKVQGDGVIVATPTGSTAYST 879

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 318 AAGASMIHPSVPAIMVTPICPHSLSFRPIVVPAGVELKISVSPESRNTSWVSFDGRNRQELFHGDSLRVTTSIYPVPCIC 397
Cdd:PLN02727 880 AAGGSMVHPNVPCMLFTPICPHSLSFRPVILPDSARLELKIPDDARSNAWVSFDGKRRQQLSRGDSVRISMSQHPLPTVN 959

                        330       340
                 ....*....|....*....|....*..
gi 161077047 398 AQDQISDWFASLADGLHWNVRKRQKCL 424
Cdd:PLN02727 960 KSDQTGDWFRSLIRCLNWNERLDQKAL 986
NadK COG0061
NAD kinase [Coenzyme transport and metabolism];
101-418 7.03e-53

NAD kinase [Coenzyme transport and metabolism];


Pssm-ID: 439831 [Multi-domain]  Cd Length: 279  Bit Score: 178.79  E-value: 7.03e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 101 TVLVIKKVSDASVLAPFVYLVDWLlQEKNMVVWVESAVLEDVqlnenvrfkairdklvtfkDGRDDLTDRIDFIVCLGGD 180
Cdd:COG0061    3 RIAIVAKPGKPEALEAAEELAELL-EERGIEVVLDEDTAVPG-------------------VPLEELGEEADLVIVLGGD 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 181 GTLLYASLLFQQSVPPVMAFHLGSLGFLTPFRFDNFEEQLTSVLEGHAALTLRSRLRCVMHRRSDRKHEAktleadldge 260
Cdd:COG0061   63 GTLLRAARLLAPLGIPILGINLGRLGFLTEIEPEELEEALERLLAGEYEVEERLLLEATVDRDGEVVHEA---------- 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 261 arpaansiLVLNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTgstayaaaagasMIHPSVPAIMVTPICPHS 340
Cdd:COG0061  133 --------LALNEVVVLRGSIARMIELEVYIDGEFLEEFRGDGLIVSTPTgstaynlsaggpIVHPGLDALVLTPIAPHT 204

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 161077047 341 LSFRPIVVPAGVELKISVSPESRNTSwVSFDGRNRQELFHGDSLRVTTSiyPVPCICAQDQISDWFASLADGLHWNVR 418
Cdd:COG0061  205 LSSRPLVLPDDSEIEIEVLEDSRPAV-LVADGQEVRDLEPGDRVEIRRS--PKPVRLLRLKDHSFFERLREKLGWGGD 279
ppnK PRK01231
NAD(+) kinase;
164-418 2.07e-41

NAD(+) kinase;


Pssm-ID: 179257 [Multi-domain]  Cd Length: 295  Bit Score: 148.95  E-value: 2.07e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 164 RDDLTDRIDFIVCLGGDGTLLYASLLFQQSVPPVMAFHLGSLGFLTPFRFDNFEEQLTSVLEGHAALtlrsrlrcvmhrr 243
Cdd:PRK01231  56 RKLLGEVCDLVIVVGGDGSLLGAARALARHNVPVLGINRGRLGFLTDIRPDELEFKLAEVLDGHYQE------------- 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 244 sdrkhEAKTLeadLDGEARPAANSI---LVLNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAG 320
Cdd:PRK01231 123 -----EERFL---LEAEVRRGGEVIgqgDALNDVVLHPGKSTRMIEFELYIDGQFVCSQRSDGLIVSTPTGSTAYALSGG 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 321 ASMIHPSVPAIMVTPICPHSLSFRPIVVPAGVELKISVSPESRNTSWVSFDGRNRQELFHGDSLRVTTSIYPVPCICAQD 400
Cdd:PRK01231 195 GPIMHPKLDAIVLVPMFPHTLSSRPIVVDGNSEIKIVISKDNRTYPRVSCDGQNSVTLAPGDTVTIRKKPQKLRLIHPLD 274

                        250
                 ....*....|....*...
gi 161077047 401 QisDWFASLADGLHWNVR 418
Cdd:PRK01231 275 Y--NYYETCRTKLGWGSR 290
ppnK PRK02155
NAD kinase;
165-416 4.42e-31

NAD kinase;


Pssm-ID: 179379 [Multi-domain]  Cd Length: 291  Bit Score: 120.82  E-value: 4.42e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 165 DDLTDRIDFIVCLGGDGTLL-YASLLFQQSVPPVMAFHlGSLGFLTPFRFDNFEEQLTSVLEGHAALTLRSRLR-CVMhr 242
Cdd:PRK02155  58 EEIGARADLAVVLGGDGTMLgIGRQLAPYGVPLIGINH-GRLGFITDIPLDDMQETLPPMLAGNYEEEERMLLEaRVV-- 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 243 rsdrKHEAKTLEAdldgearpaansiLVLNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGAS 322
Cdd:PRK02155 135 ----RDGEPIFHA-------------LAFNDVVVNRSGFSGMVELRVSVDGRFMYNQRSDGLIVATPTGSTAYALSAGGP 197

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 323 MIHPSVPAIMVTPICPHSLSFRPIVVPAGVELKISVSpESRNTSwVSFDGRNRQELFHGDSLRVTTSIYPVPCICAQDQi 402
Cdd:PRK02155 198 ILHPQLPGWVLVPIAPHTLSNRPIVLPDDSEVAIQIV-GGRDVS-VNFDMQSLTSLELGDRIEVRRSPHTVRFLHPVGY- 274

                        250
                 ....*....|....
gi 161077047 403 sDWFASLADGLHWN 416
Cdd:PRK02155 275 -SYYATLRKKLHWN 287
ppnK PRK01911
inorganic polyphosphate/ATP-NAD kinase; Provisional
 124-373 1.36e-29

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179352 [Multi-domain]  Cd Length: 292  Bit Score: 116.95  E-value: 1.36e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 124 LLQEKNMVVWVESAVLEdvQLNENVRFKairDKLVTFKDGrDDLTDRIDFIVCLGGDGTLLYASLLFQQSVPPVMAFHLG 203
Cdd:PRK01911  24 ELEERGAEVLIEEKFLD--FLKQDLKFH---PSYDTFSDN-EELDGSADMVISIGGDGTFLRTATYVGNSNIPILGINTG 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 204 SLGFLTPFRFDNFEEQLTSVLEGHAALTLRSRLRCvmhrrsdrkheakTLEADLDGEARPAansilvLNEVVIDRGPSPY 283
Cdd:PRK01911  98 RLGFLATVSKEEIEETIDELLNGDYTIEERSLLQL-------------ESNPKLFGELNFA------LNEIAILKRDTSS 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 284 LSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVPAIMVTPICPHSLSFRPIVVPAGVELKISVspESR 363
Cdd:PRK01911 159 MITVHTYLNGEYLNSYWADGLIVATPTGSTGYSLSCGGPIIVPDAKSFVITPIAPHNLNVRPLVIPDDTEITLEV--ESR 236

                        250
                 ....*....|.
gi 161077047 364 NTSW-VSFDGR 373
Cdd:PRK01911 237 SDNFlVSLDSR 247
NAD_kinase_C pfam20143
ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 271-396 3.07e-29

ATP-NAD kinase C-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86. This entry represents the C-terminal beta sandwich domain.


Pssm-ID: 437975 [Multi-domain]  Cd Length: 125  Bit Score: 110.85  E-value: 3.07e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047  271 LNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVPAIMVTPICPHSLSFRPIVVPA 350
Cdd:pfam20143   1 LNEVVYVRGPGATMIEFELYVDGELLGVDRADGLIVSTPTGSTAYSLSAGGPIISPRVLAILIVPICPHSLSSRPIVVSS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 161077047  351 gvELKISVSPESRNTSWVSFDGRNRQELFHGDSLRVTTSIYPVPCI 396
Cdd:pfam20143  81 --SSKLRIRVLSRAEALLVDDGDPELDISPGDRVRVRKSYYKAKFI 124
pnk PRK14077
NAD(+) kinase;
151-415 3.76e-29

NAD(+) kinase;


Pssm-ID: 172567 [Multi-domain]  Cd Length: 287  Bit Score: 115.65  E-value: 3.76e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 151 KAIRDKLVTFKDGRDDLTDRIDFIVCLGGDGTLLYASLLFQQSVPPVMAFHLGSLGFLTPFRFDNFEEQLTSVLEGHAAL 230
Cdd:PRK14077  45 KESAEILDLPGYGLDELFKISDFLISLGGDGTLISLCRKAAEYDKFVLGIHAGHLGFLTDITVDEAEKFFQAFFQGEFEI 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 231 TLRSRLRCVMHRRSDrkheaKTLEAdldgearpaansiLVLNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPT 310
Cdd:PRK14077 125 EKPYMLSVFLEKKQG-----KILEK-------------LAFNDVVISKNNQASMAHIEAFLNEKYFNEYFGDGVIVATPA 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 311 GSTAYAAAAGASMIHPSVPAIMVTPICPHSLSFRPIVVPAGVELKIsvspESRNTSWVSFDGRNRQELFHGDSLRVTTSI 390
Cdd:PRK14077 187 GSTAYNMSANGPIIYPLSQVFILTPVCSHSLTQRPIVLPKGFEVEF----KTKSDCILCIDGQDRYKMNDFKSIKVGLSD 262

                        250       260
                 ....*....|....*....|....*
gi 161077047 391 YPVPCICAQDQisDWFASLADGLHW 415
Cdd:PRK14077 263 KNVALIRHKNR--DYFQILKEKLHW 285
pnk PRK14076
bifunctional NADP phosphatase/NAD kinase;
125-389 6.94e-28

bifunctional NADP phosphatase/NAD kinase;


Pssm-ID: 237601 [Multi-domain]  Cd Length: 569  Bit Score: 116.37  E-value: 6.94e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 125 LQEKNMVVWVESAVLEdvqlnenvrfkAIRDKLVTFKDGRDDLTDrIDFIVCLGGDGTLLYASLLFQQSVPPVMAFHLGS 204
Cdd:PRK14076 315 LDSKGIPYELESFLYN-----------KLKNRLNEECNLIDDIEE-ISHIISIGGDGTVLRASKLVNGEEIPIICINMGT 382

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 205 LGFLTPFRFDNFEEQLTSVLEGHAALTLRSRLRCVMHRRSDRKHeaktleadldgeaRPAAnsilvLNEVVI-DRGPSPY 283
Cdd:PRK14076 383 VGFLTEFSKEEIFKAIDSIISGEYEIEKRTKLSGFILKDGHQNI-------------LPSA-----LNEVVItTKNPAKM 444

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 284 LsNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVPAIMVTPICPHSLSFRPIVVPAGVELKISVspeSR 363
Cdd:PRK14076 445 L-HFEVYVNGELVEEVRADGIIISTPTGSTAYSLSAGGPIVEPTVDGFIIVPICPFKLSSRPLVVSANSEIKIKL---LK 520

                        250       260
                 ....*....|....*....|....*.
gi 161077047 364 NTSWVSFDGRNRQELFHGDSLRVTTS 389
Cdd:PRK14076 521 KSALVVIDGSIEFEAKKGDEIIFRKS 546
ppnK PRK02645
NAD(+) kinase;
167-356 1.99e-26

NAD(+) kinase;


Pssm-ID: 179455 [Multi-domain]  Cd Length: 305  Bit Score: 108.46  E-value: 1.99e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 167 LTDRIDFIVCLGGDGTLLYAS-LLFQQSVPpVMAFHLG-SLGFLT-PFRFDNFEEQLTSVLEGHAALTLRSRLRCVMHRr 243
Cdd:PRK02645  54 ASELIDLAIVLGGDGTVLAAArHLAPHDIP-ILSVNVGgHLGFLThPRDLLQDESVWDRLQEDRYAIERRMMLQARVFE- 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 244 SDRKHEaktleadldgeaRPAANSILVLNE-----VVIDRGPSpylSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAA 318
Cdd:PRK02645 132 GDRSNE------------EPVSESYYALNDfylkpASEDRSPT---CILELEIDGEVVDQYQGDGLIVSTPTGSTAYTMA 196

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 161077047 319 AGASMIHPSVPAIMVTPICPHSLSFRPIVVPAGVELKI 356
Cdd:PRK02645 197 AGGPILHPGIDAIIVTPICPMSLSSRPIVIPPGSRVVI 234
ppnK PRK04539
inorganic polyphosphate/ATP-NAD kinase; Provisional
 164-418 4.61e-26

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 179862 [Multi-domain]  Cd Length: 296  Bit Score: 107.25  E-value: 4.61e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 164 RDDLTDRIDFIVCLGGDGTLLYASLLFQQSVPPVMAFHLGSLGFLTPFRFDNFEEQLTSVLEGHAALTLRSRLRCVMHRr 243
Cdd:PRK04539  62 KTELGQYCDLVAVLGGDGTFLSVAREIAPRAVPIIGINQGHLGFLTQIPREYMTDKLLPVLEGKYLAEERILIEAALIR- 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 244 sdrkhEAKTLEadldgearpaanSILVLNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGASM 323
Cdd:PRK04539 141 -----EGKTAE------------RALALNDAVLSRGGAGQMIEFEVFVNREFVYTQRSDGLIVSTPTGSTAYSLAAGGPI 203

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 324 IHPSVPAIMVTPICPHSLSFRPIVVPAGVELKISVSP--ESRntswVSFDGRNRQELFHGDslRVTTSIYPVPCICAQDQ 401
Cdd:PRK04539 204 MQAGLHAFTLVPICPQSMTNRPIAIPDTSEIEILVTQggDAR----VHFDGQTHIDVQNLD--RITIRRYRNPLRILHPT 277

                        250
                 ....*....|....*..
gi 161077047 402 ISDWFASLADGLHWNVR 418
Cdd:PRK04539 278 DYQYFKTLRQKLHWGEQ 294
ppnK PRK03378
inorganic polyphosphate/ATP-NAD kinase; Provisional
 101-372 9.87e-25

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235122 [Multi-domain]  Cd Length: 292  Bit Score: 103.48  E-value: 9.87e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 101 TVLVIKKVSDASVLAPFVYLVDWLLqEKNMVVWVESAVLEDVQLNenvrfKAIRDKLVtfkdgrdDLTDRIDFIVCLGGD 180
Cdd:PRK03378   7 CIGIVGHPRHPTALTTHEMLYHWLT-SKGYEVIVEQQIAHELQLK-----NVKTGTLA-------EIGQQADLAIVVGGD 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 181 GTLLYASLLFQQSVPPVMAFHLGSLGFLTPFRFDNFEEQLTSVLEGHAALTLRSRLRCVMHRRSDRKheaktleadldge 260
Cdd:PRK03378  74 GNMLGAARVLARYDIKVIGINRGNLGFLTDLDPDNALQQLSDVLEGHYISEKRFLLEAQVCRHGQQK------------- 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 261 arpAANSilVLNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVPAIMVTPICPHS 340
Cdd:PRK03378 141 ---RIST--AINEVVLHPGKVAHMIEFEVYIDDNFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHT 215

                        250       260       270
                 ....*....|....*....|....*....|..
gi 161077047 341 LSFRPIVVPAGVELKISVSPeSRNTSWVSFDG 372
Cdd:PRK03378 216 LSARPLVIDSSSTIRLKFSP-NRSDLEISCDS 246
ppnK PRK03708
NAD(+) kinase;
171-389 7.39e-23

NAD(+) kinase;


Pssm-ID: 179635 [Multi-domain]  Cd Length: 277  Bit Score: 97.86  E-value: 7.39e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 171 IDFIVCLGGDGTLLYASLLFQQSVPpVMAFHLGSLGFLTPFRFDNFEEQLTSVLEGHAALTLRSRLRCVmhrrsdrkhea 250
Cdd:PRK03708  58 VDFIIAIGGDGTILRIEHKTKKDIP-ILGINMGTLGFLTEVEPEETFFALSRLLEGDYFIDERIKLRVY----------- 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 251 ktleadLDGEARPAAnsilvLNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVPA 330
Cdd:PRK03708 126 ------INGENVPDA-----LNEVVILTGIPGKIIHLKYYVDGELADEVRADGLIISTPTGSTAYAMSAGGPFVDPRLDA 194

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 161077047 331 IMVTPICPHSLSFRPIVVPAGVELKISVSPESRNTSwVSFDGRNRQELFHGDSLRVTTS 389
Cdd:PRK03708 195 ILIAPLCPFKLSSRPMVVPSSSRIDVKLLRTGREII-LVIDGQYYEELPPDTEITIKKS 252
ppnK PRK01185
NAD(+) kinase;
161-389 2.51e-18

NAD(+) kinase;


Pssm-ID: 179241 [Multi-domain]  Cd Length: 271  Bit Score: 84.48  E-value: 2.51e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 161 KDGRDDLTDRIDFIVCLGGDGTLLyasLLFQQSVPPVMAFHLGSLGFLTPFRFDNFEEQLTSVLEGHAALTLRSRLRCVM 240
Cdd:PRK01185  43 MDGLDIEEINADVIITIGGDGTIL---RTLQRAKGPILGINMGGLGFLTEIEIDEVGSAIKKLIRGEYFIDERMKLKVYI 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 241 HrrSDRKHEAktleadldgearpaansilvLNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAG 320
Cdd:PRK01185 120 N--GERLEDC--------------------TNEAVIHTDRIAKIRQFKIYYDGHFLDTFKADGVIVATPTGSTSYSSSAG 177

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 161077047 321 ASMIHPSVPAIMVTPICPHSLSFRPIVVPAGVELKISVSPESRNTswVSFDGRNRQELFHGDSLRVTTS 389
Cdd:PRK01185 178 GPILLPNLEGMVISYIAPYSSRPKSVVVPSESTVEIKIAGDQSSL--LILDGQYEYKISKGDTVEISKS 244
ppnK PRK02649
NAD(+) kinase;
171-415 8.30e-18

NAD(+) kinase;


Pssm-ID: 179456 [Multi-domain]  Cd Length: 305  Bit Score: 83.49  E-value: 8.30e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 171 IDFIVCLGGDGTLLYAsllFQQSVP---PVMAFHLGSLGFLTPFRFDNFEEQLTSVLEGHAALTLRSRLRCVMHRRSDRK 247
Cdd:PRK02649  69 MKFAIVLGGDGTVLSA---ARQLAPcgiPLLTINTGHLGFLTEAYLNQLDEAIDQVLAGQYTIEERTMLTVSVMRGDQLR 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 248 HEAktleadldgearpaansiLVLNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPS 327
Cdd:PRK02649 146 WEA------------------LSLNEMVLHREPLTSMCHFEIAIGRHAPVDIAADGVILSTPTGSTAYSLSAGGPVITPD 207

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 328 VPAIMVTPICPHSLSFRPIVVPAgvELKISVSPESRNTSWVSFDGRNRQELFHGDSLRVTTSIYPVPCICAQDQisDWFA 407
Cdd:PRK02649 208 VPVLQLTPICPHSLASRALVFSD--SEPVTVFPATPERLVMVVDGNAGCYVWPEDRVLIRRSPYPVRFIRLQDP--EFFR 283


                 ....*...
gi 161077047 408 SLADGLHW 415
Cdd:PRK02649 284 VLREKLGW 291
ppnK PRK02231
NAD(+) kinase;
120-366 3.23e-17

NAD(+) kinase;


Pssm-ID: 167337 [Multi-domain]  Cd Length: 272  Bit Score: 81.39  E-value: 3.23e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 120 LVDWLLqEKNMVVWVESAVLEDVQLNENvrfkairdKLVTFkdgrDDLTDRIDFIVCLGGDGTLL-YASLLFQQSVPpVM 198
Cdd:PRK02231   5 LFHWLK-ERGYQVLVEKEIAEQLNLPEN--------HLASL----EEIGQRAQLAIVIGGDGNMLgRARVLAKYDIP-LI 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 199 AFHLGSLGFLTPFRFDNFEEQLTSVLEghaaltlrsRLRCVMHRRSdrkheakTLEADL--DGEARPAANSIlvlNEVVI 276
Cdd:PRK02231  71 GINRGNLGFLTDIDPKNAYEQLEACLE---------RGEFFVEERF-------LLEAKIerNGKIIATSNAL---NEVVI 131

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 277 DRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVPAIMVTPICPHSLSFRPIVVPAgvELKI 356
Cdd:PRK02231 132 HPAKIAHMIDFHVYIDDKFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPNLNAIALVPMFPHTLSSRPLVIDG--DSKI 209

                        250
                 ....*....|
gi 161077047 357 SVSPESRNTS 366
Cdd:PRK02231 210 SLRFAEYNTP 219
NAD_kinase pfam01513
ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, ...
 120-225 7.12e-16

ATP-NAD kinase N-terminal domain; Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilizing ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86.


Pssm-ID: 426300 [Multi-domain]  Cd Length: 128  Bit Score: 73.94  E-value: 7.12e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047  120 LVDWLLQEKNMVVWVESAVLEDVQLNENVRFKAI--RDKLVTF--KDGRDDLTDRIDFIVCLGGDGTLLYASLLFQQSVP 195
Cdd:pfam01513  19 VARWLLDRLGITVTVEEKMGESLAFAAGDRPEVIgcLKKVVDDtrRATRAFADAGVDLIIVLGGDGTALRAARLLQKAVI 98

                          90       100       110
                  ....*....|....*....|....*....|
gi 161077047  196 PVMAFHLGSLGFLTPFRFDNFEEQLTSVLE 225
Cdd:pfam01513  99 PILGVNTGVLGFLTEFEPEAAFELLERLLE 128
pnk PRK14075
NAD(+) kinase;
171-361 3.49e-14

NAD(+) kinase;


Pssm-ID: 184489 [Multi-domain]  Cd Length: 256  Bit Score: 72.07  E-value: 3.49e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 171 IDFIVCLGGDGTLLYASllfQQSVPPVMAFHLGSLGFLTPFRFDNFEEQLTSVLEGHAALTLRSRLRcvmhrrsdrkheA 250
Cdd:PRK14075  42 ADLIIVVGGDGTVLKAA---KKVGTPLVGFKAGRLGFLSSYTLEEIDRFLEDLKNWNFREEKRWFLK------------I 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 251 KTLEADLDgearpaansilVLNEVVIDRGPSPYLSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVPA 330
Cdd:PRK14075 107 ESELGNHL-----------ALNDVTLERDPSQKMVEIEVSFEDHSSMWFFADGVVISTPTGSTAYSLSLGGPIILPNCEV 175

                        170       180       190
                 ....*....|....*....|....*....|.
gi 161077047 331 IMVTPICPHSLSFRPIVVPAGVELKISVSPE 361
Cdd:PRK14075 176 FEITPIAPQFLATRSIVIPSNEKVTVESQRD 206
ppnK PRK03372
inorganic polyphosphate/ATP-NAD kinase; Provisional
 124-393 4.48e-11

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235121 [Multi-domain]  Cd Length: 306  Bit Score: 63.78  E-value: 4.48e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 124 LLQEKNMVVWVESAVLEDVQLNENVRFKAIRDKLVtfkDGRDDLTDRIDFIVCLGGDGTLLYASLLFQQSVPPVMAFHLG 203
Cdd:PRK03372  29 QLGDAGIGVRVLDAEAVDLGATHPAPDDFRAMEVV---DADPDAADGCELVLVLGGDGTILRAAELARAADVPVLGVNLG 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 204 SLGFLTPFRFDNFEEQLTSVLeghaaltlrsrlrcvmhRRSDRKHEAKTLEADLDGEARPAANSiLVLNEVVIDRGPSPY 283
Cdd:PRK03372 106 HVGFLAEAEAEDLDEAVERVV-----------------DRDYRVEERMTLDVTVRVGGEIVWRG-WALNEASLEKADREG 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 284 LSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVPAIMVTPICPHSLSFRPIVVPAGVELKISVSPESr 363
Cdd:PRK03372 168 MLEVVLEVDGRPVSSFGCDGVLVSTPTGSTAYAFSAGGPVVWPDLEALLVVPLNAHALFARPLVVSPTSTVAVEILADT- 246

                        250       260       270
                 ....*....|....*....|....*....|
gi 161077047 364 NTSWVSFDGRNRQELFHGDSLRVTTSIYPV 393
Cdd:PRK03372 247 SDAVLWCDGRRSVDLPPGARVEVRRGATPV 276
ppnK PRK04885
inorganic polyphosphate/ATP-NAD kinase; Provisional
 145-372 6.95e-10

inorganic polyphosphate/ATP-NAD kinase; Provisional


Pssm-ID: 235317 [Multi-domain]  Cd Length: 265  Bit Score: 59.45  E-value: 6.95e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 145 NENVRFKAIRDKLVT-FKDGRDDLTDRI-DFIVCLGGDGTLLYAsllFQQSVPPV--MAF---HLGSLGFLTPFRfdNFE 217
Cdd:PRK04885   8 NGDPKSKRVASKLKKyLKDFGFILDEKNpDIVISVGGDGTLLSA---FHRYENQLdkVRFvgvHTGHLGFYTDWR--PFE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 218 -EQLtsvleghaaltlrsrlrcVMHRRSDRKHEAK--TLEADL---DGEARpaanSILVLNEVVIDRgPSPYLSnIDLFL 291
Cdd:PRK04885  83 vDKL------------------VIALAKDPGQVVSypLLEVKItyeDGEKE----KYLALNEATIKR-IEGTLV-ADVYI 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 292 DGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSVPAIMVTPICphSLS---FR----PIVVPAGVelKISVSPESRN 364
Cdd:PRK04885 139 NGVLFERFRGDGLCVSTPTGSTAYNKSLGGAVLHPSIEALQLTEIA--SINnrvFRtlgsPLILPKHH--TITLKPVNDD 214


                 ....*...
gi 161077047 365 TSWVSFDG 372
Cdd:PRK04885 215 DYQITVDH 222
ppnK PRK03501
NAD kinase;
174-310 2.38e-06

NAD kinase;


Pssm-ID: 179584  Cd Length: 264  Bit Score: 48.82  E-value: 2.38e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 174 IVCLGGDGTLLYA--SLLFQQSVPPVMAFHLGSLGFLTPFRFDNFEEQLtsvlegHAALTLRSRLRcvmhrrsdrkhEAK 251
Cdd:PRK03501  43 IVSIGGDGTFLQAvrKTGFREDCLYAGISTKDQLGFYCDFHIDDLDKMI------QAITKEEIEVR-----------KYP 105

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 161077047 252 TLEADLDGEarpaaNSILVLNEVVIDRGPSPYLSnIDLFLDGKYITSVQGDGLIVSTPT 310
Cdd:PRK03501 106 TIEVTVDGS-----TSFYCLNEFSIRSSIIKTFV-IDVYIDDLHFETFRGDGMVVSTPT 158
ppnK PRK00561
NAD(+) kinase;
169-358 1.06e-05

NAD(+) kinase;


Pssm-ID: 100598 [Multi-domain]  Cd Length: 259  Bit Score: 46.79  E-value: 1.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 169 DRIDFIVCLGGDGTLLYASLLFQQSVPPVMAFHLGSLGFLTPFRFDNFEEQLTSVLEghaaltlrsrlRCVMHRRSdrkh 248
Cdd:PRK00561  32 DGADYLFVLGGDGFFVSTAANYNCAGCKVVGINTGHLGFYTSFNETDLDQNFANKLD-----------QLKFTQID---- 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 249 eakTLEADLDGEarpaanSILVLNEVVIDrgpSPYLSNIDLFLDGKYITSVQGDGLIVSTPTGSTAYAAAAGASMIHPSV 328
Cdd:PRK00561  97 ---LLEVQIDDQ------IHLVLNELAVY---TNTAYPINIFIDNEFWEKYRGSGLLIGPRTGSTALAKSAKGAVIFPRI 164

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 161077047 329 PAIMVTPICP--HSlSF----RPIVVPAGVELKISV 358
Cdd:PRK00561 165 DVIQIIELNPllHP-NQttiqSPIILPIDTKVEFEI 199
PLN02929 PLN02929
NADH kinase
 164-309 1.20e-05

NADH kinase


Pssm-ID: 215502 [Multi-domain]  Cd Length: 301  Bit Score: 46.95  E-value: 1.20e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 164 RDDLTDRI---DFIVCLGGDGTLLYASLLFQQSVPPvmafhLG----------------------SLGFLTPFRFDNFEE 218
Cdd:PLN02929  55 RNELSQPIrdvDLVVAVGGDGTLLQASHFLDDSIPV-----LGvnsdptqkdeveeysdefdarrSTGHLCAATAEDFEQ 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 219 QLTSVLEGHAALTLRSRLRCVmhrrsdrkheaktleadLDGE--ARPAANSILVLN-----------EVVIDRGPSPYLS 285
Cdd:PLN02929 130 VLDDVLFGRLKPTELSRISTV-----------------VNGTllETPALNDVLIAHpspaavsrfsfRVGRQGGSSGPLI 192

                        170       180
                 ....*....|....*....|....
gi 161077047 286 NidlfldgkyitsVQGDGLIVSTP 309
Cdd:PLN02929 193 N------------VRSSGLRVSTA 204
ppnK PRK04761
inorganic polyphosphate/ATP-NAD kinase; Reviewed
 169-309 1.01e-04

inorganic polyphosphate/ATP-NAD kinase; Reviewed


Pssm-ID: 179876 [Multi-domain]  Cd Length: 246  Bit Score: 43.65  E-value: 1.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 161077047 169 DRIDFIVCLGGDGTLLYASLLFQQSVPPVMAFHLGSLGFL-TPFRFDNFEEQLTsvlegHAALTLRSRLRCVMHRRSDRK 247
Cdd:PRK04761  24 EEADVIVALGGDGFMLQTLHRYMNSGKPVYGMNRGSVGFLmNEYSEDDLLERIA-----AAEPTVLHPLRMTATDVSGEV 98

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 161077047 248 HEAktleadldgearpaansiLVLNEVVIDRGpSPYLSNIDLFLDGKYITS-VQGDGLIVSTP 309
Cdd:PRK04761  99 HEA------------------LAINEVSLFRQ-TRQAAKLRISIDGKVRMEeLVCDGVLVATP 142
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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