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Conserved domains on  [gi|79327369|ref|NP_001031859|]
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CD2-binding protein-like protein [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
OCRE super family cl23757
OCRE domain; The OCRE (OCtamer REpeat) domain contains 5 repeats of an 8-residue motif, which ...
294-340 1.22e-06

OCRE domain; The OCRE (OCtamer REpeat) domain contains 5 repeats of an 8-residue motif, which were shown to form beta-strands. Based on the architectures of proteins containing OCRE domains, a role in RNA metabolism and/or signalling has been proposed.


The actual alignment was detected with superfamily member cd16166:

Pssm-ID: 304914  Cd Length: 54  Bit Score: 44.98  E-value: 1.22e-06
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 79327369 294 SDYVFDESSGYYYSSSLGYYYDPNTGLYCYATTGKWY--DEETKEYKEV 340
Cdd:cd16166   6 SGFVYDPASGYYYDASSGYYYDANTGLYYDAASGRWYsyDEETGQYVEV 54
 
Name Accession Description Interval E-value
OCRE_SUA_like cd16166
OCRE domain found in Suppressor of ABI3-5 (SUA) and similar proteins; SUA is an RNA-binding ...
294-340 1.22e-06

OCRE domain found in Suppressor of ABI3-5 (SUA) and similar proteins; SUA is an RNA-binding protein located in the nucleus and expressed in all plant tissues. It functions as a splicing factor that influences seed maturation by controlling alternative splicing of ABI3. The suppression of the cryptic ABI3 intron indicates a role of SUA in mRNA processing. SUA also interacts with the prespliceosomal component U2AF65, the larger subunit of the conserved pre-mRNA splicing factor U2AF. SUA contains two RNA recognition motifs surrounding a zinc finger domain, an OCtamer REpeat (OCRE) domain, and a Gly-rich domain close to the C-terminus.


Pssm-ID: 293885  Cd Length: 54  Bit Score: 44.98  E-value: 1.22e-06
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 79327369 294 SDYVFDESSGYYYSSSLGYYYDPNTGLYCYATTGKWY--DEETKEYKEV 340
Cdd:cd16166   6 SGFVYDPASGYYYDASSGYYYDANTGLYYDAASGRWYsyDEETGQYVEV 54
OCRE pfam17780
OCRE domain; The OCtamer REpeat (OCRE) has been annotated as a 42-residue sequence motif with ...
315-340 1.79e-05

OCRE domain; The OCtamer REpeat (OCRE) has been annotated as a 42-residue sequence motif with 12 tyrosine residues in the spliceosome trans-regulatory elements RBM5 and RBM10 (RBM [RNA-binding motif]), which are known to regulate alternative splicing of Fas and Bcl-x pre-mRNA transcripts. The structure of the domain consists of an anti-parallel arrangement of six beta strands.


Pssm-ID: 465502  Cd Length: 51  Bit Score: 41.46  E-value: 1.79e-05
                          10        20
                  ....*....|....*....|....*...
gi 79327369   315 DPNTGLYCYATTGKWY--DEETKEYKEV 340
Cdd:pfam17780  24 DPNTGLYYDPATGKYYtyDEETKSYVPH 51
 
Name Accession Description Interval E-value
OCRE_SUA_like cd16166
OCRE domain found in Suppressor of ABI3-5 (SUA) and similar proteins; SUA is an RNA-binding ...
294-340 1.22e-06

OCRE domain found in Suppressor of ABI3-5 (SUA) and similar proteins; SUA is an RNA-binding protein located in the nucleus and expressed in all plant tissues. It functions as a splicing factor that influences seed maturation by controlling alternative splicing of ABI3. The suppression of the cryptic ABI3 intron indicates a role of SUA in mRNA processing. SUA also interacts with the prespliceosomal component U2AF65, the larger subunit of the conserved pre-mRNA splicing factor U2AF. SUA contains two RNA recognition motifs surrounding a zinc finger domain, an OCtamer REpeat (OCRE) domain, and a Gly-rich domain close to the C-terminus.


Pssm-ID: 293885  Cd Length: 54  Bit Score: 44.98  E-value: 1.22e-06
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 79327369 294 SDYVFDESSGYYYSSSLGYYYDPNTGLYCYATTGKWY--DEETKEYKEV 340
Cdd:cd16166   6 SGFVYDPASGYYYDASSGYYYDANTGLYYDAASGRWYsyDEETGQYVEV 54
OCRE pfam17780
OCRE domain; The OCtamer REpeat (OCRE) has been annotated as a 42-residue sequence motif with ...
315-340 1.79e-05

OCRE domain; The OCtamer REpeat (OCRE) has been annotated as a 42-residue sequence motif with 12 tyrosine residues in the spliceosome trans-regulatory elements RBM5 and RBM10 (RBM [RNA-binding motif]), which are known to regulate alternative splicing of Fas and Bcl-x pre-mRNA transcripts. The structure of the domain consists of an anti-parallel arrangement of six beta strands.


Pssm-ID: 465502  Cd Length: 51  Bit Score: 41.46  E-value: 1.79e-05
                          10        20
                  ....*....|....*....|....*...
gi 79327369   315 DPNTGLYCYATTGKWY--DEETKEYKEV 340
Cdd:pfam17780  24 DPNTGLYYDPATGKYYtyDEETKSYVPH 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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