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Conserved domains on  [gi|71981152|ref|NP_001021259|]
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Leucine-rich repeat protein soc-2 [Caenorhabditis elegans]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
75-421 2.16e-37

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 143.15  E-value: 2.16e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  75 DQRLDLSSIEITSIPSPIKELTQLTELFLYKNKltclptEIGQLVNLKKLGLSENALTSLPDSLASLESLETLDLRHNKL 154
Cdd:COG4886  75 LLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQL 148

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 155 TEVPSVIYKIGSLETLWLRYNRIVAVDEQIGNLSKLKMLDVRENKIRELPSAIGKLTSLVVCLVSYNHLTRVPEEIGDCH 234
Cdd:COG4886 149 TDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLT 228

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 235 SLTQLDLQHNDLSELPySIGKLVNLVRIGIRYNKIRCIPSELEsCQQLEEFIVESNHLQLLppnLLTMLPKIHTVNLSRN 314
Cdd:COG4886 229 NLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPPLAN-LTNLKTLDLSNNQLTDL---KLKELELLLGLNSLLL 303

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 315 ELTAFPAGGPQQFVSTVTINMEHNQISKIPIGIFSKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDI 394
Cdd:COG4886 304 LLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLA 383

                       330       340
                ....*....|....*....|....*..
gi 71981152 395 EKLVNLEILVLSNNQLKKLPNQIGNLN 421
Cdd:COG4886 384 LLLLTLLLLLLTTTAGVLLLTLALLDA 410
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
338-532 2.43e-25

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 108.48  E-value: 2.43e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 338 NQISKIPIGIFSKATRLTKLNLKENELVSlpldmgSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQI 417
Cdd:COG4886  82 LSLLLLGLTDLGDLTNLTELDLSGNEELS------NLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPL 155

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 418 GNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQDLRLGENNLTAIPEEIGHLDSLKSLYL 497
Cdd:COG4886 156 GNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDL 235

                       170       180       190
                ....*....|....*....|....*....|....*
gi 71981152 498 NDNsSLHNLPfELALCQSLEIMSIENSPLSQIPPE 532
Cdd:COG4886 236 SNN-QLTDLP-ELGNLTNLEELDLSNNQLTDLPPL 268
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
75-421 2.16e-37

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 143.15  E-value: 2.16e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  75 DQRLDLSSIEITSIPSPIKELTQLTELFLYKNKltclptEIGQLVNLKKLGLSENALTSLPDSLASLESLETLDLRHNKL 154
Cdd:COG4886  75 LLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQL 148

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 155 TEVPSVIYKIGSLETLWLRYNRIVAVDEQIGNLSKLKMLDVRENKIRELPSAIGKLTSLVVCLVSYNHLTRVPEEIGDCH 234
Cdd:COG4886 149 TDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLT 228

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 235 SLTQLDLQHNDLSELPySIGKLVNLVRIGIRYNKIRCIPSELEsCQQLEEFIVESNHLQLLppnLLTMLPKIHTVNLSRN 314
Cdd:COG4886 229 NLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPPLAN-LTNLKTLDLSNNQLTDL---KLKELELLLGLNSLLL 303

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 315 ELTAFPAGGPQQFVSTVTINMEHNQISKIPIGIFSKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDI 394
Cdd:COG4886 304 LLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLA 383

                       330       340
                ....*....|....*....|....*..
gi 71981152 395 EKLVNLEILVLSNNQLKKLPNQIGNLN 421
Cdd:COG4886 384 LLLLTLLLLLLTTTAGVLLLTLALLDA 410
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 78-533 2.35e-27

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 117.26  E-value: 2.35e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152   78 LDLSSIEITSiPSPIKELTQLTELFLYKNKLTC-LPTEIGQLVNLKKLGLSENALTS-LPDSLASLESLETLDLRHNKLT 155
Cdd:PLN00113 123 LNLSNNNFTG-SIPRGSIPNLETLDLSNNMLSGeIPNDIGSFSSLKVLDLGGNVLVGkIPNSLTNLTSLEFLTLASNQLV 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  156 -EVPSVIYKIGSLETLWLRYNRIVA-VDEQIGNLSKLKMLD-VRENKIRELPSAIGKLTSLVVCLVSYNHLT-RVPEEIG 231
Cdd:PLN00113 202 gQIPRELGQMKSLKWIYLGYNNLSGeIPYEIGGLTSLNHLDlVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIF 281

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  232 DCHSLTQLDLQHNDLS-ELPYSIGKLvnlvrigirynkircipselescQQLEEFIVESNHLQLLPPNLLTMLPKIHTVN 310
Cdd:PLN00113 282 SLQKLISLDLSDNSLSgEIPELVIQL-----------------------QNLEILHLFSNNFTGKIPVALTSLPRLQVLQ 338

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  311 LSRNELTA-FPAGGPQQFVSTVTINMEHNQISKIPIGIFSKAtRLTKLNLKENELVS-LPLDMGSWTSITELNLSTNQLK 388
Cdd:PLN00113 339 LWSNKFSGeIPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSG-NLFKLILFSNSLEGeIPKSLGACRSLRRVRLQDNSFS 417

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  389 -VLPEDIEKLVNLEILVLSNNQLKklpnqiGNLNKLR--------ELDLEENELETVPTEIGfLQHLTKLWVQSNKIL-T 458
Cdd:PLN00113 418 gELPSEFTKLPLVYFLDISNNNLQ------GRINSRKwdmpslqmLSLARNKFFGGLPDSFG-SKRLENLDLSRNQFSgA 490

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 71981152  459 LPRSIGNLCSLQDLRLGENNLTA-IPEEIGHLDSLKSLYLNDNSSLHNLPFELALCQSLEIMSIENSPLS-QIPPEI 533
Cdd:PLN00113 491 VPRKLGSLSELMQLKLSENKLSGeIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSgEIPKNL 567
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
338-532 2.43e-25

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 108.48  E-value: 2.43e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 338 NQISKIPIGIFSKATRLTKLNLKENELVSlpldmgSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQI 417
Cdd:COG4886  82 LSLLLLGLTDLGDLTNLTELDLSGNEELS------NLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPL 155

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 418 GNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQDLRLGENNLTAIPEEIGHLDSLKSLYL 497
Cdd:COG4886 156 GNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDL 235

                       170       180       190
                ....*....|....*....|....*....|....*
gi 71981152 498 NDNsSLHNLPfELALCQSLEIMSIENSPLSQIPPE 532
Cdd:COG4886 236 SNN-QLTDLP-ELGNLTNLEELDLSNNQLTDLPPL 268
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 303-545 3.52e-15

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 79.12  E-value: 3.52e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  303 LPKIHTVNLSRNELTAfpaGGPQQFVSTVT----INMEHNQIS-KIPIGIFSKatrLTKLNLKENELV-SLPLDMGSWTS 376
Cdd:PLN00113  92 LPYIQTINLSNNQLSG---PIPDDIFTTSSslryLNLSNNNFTgSIPRGSIPN---LETLDLSNNMLSgEIPNDIGSFSS 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  377 ITELNLSTNQLK-VLPEDIEKLVNLEILVLSNNQL-KKLPNQIGNL-NKLRELDLEENELETVPTEIGFLQHLTKL-WVQ 452
Cdd:PLN00113 166 LKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLvGQIPRELGQMkSLKWIYLGYNNLSGEIPYEIGGLTSLNHLdLVY 245

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  453 SNKILTLPRSIGNLCSLQDLRLGENNLTA-IPEEIGHLDSLKSLYLNDNSSLHNLPFELALCQSLEIMSIENSPLSQIPP 531
Cdd:PLN00113 246 NNLTGPIPSSLGNLKNLQYLFLYQNKLSGpIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIP 325

                        250
                 ....*....|....
gi 71981152  532 EITAGGPSLVIQYL 545
Cdd:PLN00113 326 VALTSLPRLQVLQL 339
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 78-244 8.35e-10

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 59.03  E-value: 8.35e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  78 LDLSSIEITSIPSpIKELTQLTELFLYKNKLTCLPtEIGQLVNLKKLGLSENALTSLpDSLASLESLETLDLRHNKLTEV 157
Cdd:cd21340   7 LYLNDKNITKIDN-LSLCKNLKVLYLYDNKITKIE-NLEFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 158 pSVIYKIGSLETLWLRYNRI-----VAVDEQ-IGNLSK-LKMLDVRENKIRELpSAIGKLTSLVVCLVSYNHLTRVPE-- 228
Cdd:cd21340  84 -EGLENLTNLEELHIENQRLppgekLTFDPRsLAALSNsLRVLNISGNNIDSL-EPLAPLRNLEQLDASNNQISDLEEll 161

                       170
                ....*....|....*..
gi 71981152 229 -EIGDCHSLTQLDLQHN 244
Cdd:cd21340 162 dLLSSWPSLRELDLTGN 178
LRR_8 pfam13855
Leucine rich repeat;
120-177 6.68e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 43.67  E-value: 6.68e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152   120 NLKKLGLSENALTSL-PDSLASLESLETLDLRHNKLTEV-PSVIYKIGSLETLWLRYNRI 177
Cdd:pfam13855   2 NLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 375-529 3.97e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 42.08  E-value: 3.97e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 375 TSITELNLSTNQLKVLpEDIEKLVNLEILVLSNNQLKKLPNqignlnklreldleeneletvpteIGFLQHLTKLWVQSN 454
Cdd:cd21340   2 KRITHLYLNDKNITKI-DNLSLCKNLKVLYLYDNKITKIEN------------------------LEFLTNLTHLYLQNN 56

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 455 KILTLPrSIGNLCSLQDLRLGENNLTAIpEEIGHLDSLKSLYLNDNSSLHNLPFE------LALCQSLEIMSIENSPLSQ 528
Cdd:cd21340  57 QIEKIE-NLENLVNLKKLYLGGNRISVV-EGLENLTNLEELHIENQRLPPGEKLTfdprslAALSNSLRVLNISGNNIDS 134


                .
gi 71981152 529 I 529
Cdd:cd21340 135 L 135
LRR_8 pfam13855
Leucine rich repeat;
444-500 7.62e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.89  E-value: 7.62e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 71981152   444 QHLTKLWVQSNKILTL-PRSIGNLCSLQDLRLGENNLTAI-PEEIGHLDSLKSLYLNDN 500
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGN 59
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
75-421 2.16e-37

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 143.15  E-value: 2.16e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  75 DQRLDLSSIEITSIPSPIKELTQLTELFLYKNKltclptEIGQLVNLKKLGLSENALTSLPDSLASLESLETLDLRHNKL 154
Cdd:COG4886  75 LLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQL 148

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 155 TEVPSVIYKIGSLETLWLRYNRIVAVDEQIGNLSKLKMLDVRENKIRELPSAIGKLTSLVVCLVSYNHLTRVPEEIGDCH 234
Cdd:COG4886 149 TDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLT 228

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 235 SLTQLDLQHNDLSELPySIGKLVNLVRIGIRYNKIRCIPSELEsCQQLEEFIVESNHLQLLppnLLTMLPKIHTVNLSRN 314
Cdd:COG4886 229 NLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPPLAN-LTNLKTLDLSNNQLTDL---KLKELELLLGLNSLLL 303

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 315 ELTAFPAGGPQQFVSTVTINMEHNQISKIPIGIFSKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDI 394
Cdd:COG4886 304 LLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLA 383

                       330       340
                ....*....|....*....|....*..
gi 71981152 395 EKLVNLEILVLSNNQLKKLPNQIGNLN 421
Cdd:COG4886 384 LLLLTLLLLLLTTTAGVLLLTLALLDA 410
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
72-421 2.70e-35

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 137.37  E-value: 2.70e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  72 EAQDQRLDLSSIEITSIPSPIKELTQLTELFLYKNKLTCLPTEIGQLVNLKKLGLSENaltslpDSLASLESLETLDLRH 151
Cdd:COG4886  49 LTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN------EELSNLTNLESLDLSG 122

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 152 NKLTEVPSVIYKIGSLETLWLRYNRIVAVDEQIGNLSKLKMLDVRENKIRELPSAIGKLTSLVVCLVSYNHLTRVPEEIG 231
Cdd:COG4886 123 NQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLG 202

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 232 DCHSLTQLDLQHNDLSELPYSIGKLVNLVRIGIRYNKIRCIPsELESCQQLEEFIVESNHLQLLPPNLLtmLPKIHTVNL 311
Cdd:COG4886 203 NLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPPLAN--LTNLKTLDL 279

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 312 SRNELTAF---PAGGPQQFVSTVTINMEHNQISKIPIGIFSKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLK 388
Cdd:COG4886 280 SNNQLTDLklkELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLL 359

                       330       340       350
                ....*....|....*....|....*....|...
gi 71981152 389 VLPEDIEKLVNLEILVLSNNQLKKLPNQIGNLN 421
Cdd:COG4886 360 SLLLTLLLTLGLLGLLEATLLTLALLLLTLLLL 392
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
78-490 2.80e-33

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 131.59  E-value: 2.80e-33
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  78 LDLSSIEITSIPSPIKELTQLTELFLYKNKLTCLPTEIGQLVNLKKLGLSENALTSLPDSLASLESLETLDLRHNKLtev 157
Cdd:COG4886  32 LLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEE--- 108

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 158 psvIYKIGSLETLWLRYNRIVAVDEQIGNLSKLKMLDVRENKIRELPSAIGKLTSLVVCLVSYNHLTRVPEEIGDCHSLT 237
Cdd:COG4886 109 ---LSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLK 185

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 238 QLDLQHNDLSELPYSIGKLVNLVRIGIRYNKIRCIPSELESCQQLEEFIVESNHLQLLPPnlLTMLPKIHTVNLSRNELT 317
Cdd:COG4886 186 ELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPE--LGNLTNLEELDLSNNQLT 263

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 318 AFPAGGpqqfvstvtinmehnqiskipigifsKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKL 397
Cdd:COG4886 264 DLPPLA--------------------------NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILL 317

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 398 VNLEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQDLRLGEN 477
Cdd:COG4886 318 LLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTT 397

                       410
                ....*....|...
gi 71981152 478 NLTAIPEEIGHLD 490
Cdd:COG4886 398 AGVLLLTLALLDA 410
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 78-533 2.35e-27

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 117.26  E-value: 2.35e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152   78 LDLSSIEITSiPSPIKELTQLTELFLYKNKLTC-LPTEIGQLVNLKKLGLSENALTS-LPDSLASLESLETLDLRHNKLT 155
Cdd:PLN00113 123 LNLSNNNFTG-SIPRGSIPNLETLDLSNNMLSGeIPNDIGSFSSLKVLDLGGNVLVGkIPNSLTNLTSLEFLTLASNQLV 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  156 -EVPSVIYKIGSLETLWLRYNRIVA-VDEQIGNLSKLKMLD-VRENKIRELPSAIGKLTSLVVCLVSYNHLT-RVPEEIG 231
Cdd:PLN00113 202 gQIPRELGQMKSLKWIYLGYNNLSGeIPYEIGGLTSLNHLDlVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIF 281

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  232 DCHSLTQLDLQHNDLS-ELPYSIGKLvnlvrigirynkircipselescQQLEEFIVESNHLQLLPPNLLTMLPKIHTVN 310
Cdd:PLN00113 282 SLQKLISLDLSDNSLSgEIPELVIQL-----------------------QNLEILHLFSNNFTGKIPVALTSLPRLQVLQ 338

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  311 LSRNELTA-FPAGGPQQFVSTVTINMEHNQISKIPIGIFSKAtRLTKLNLKENELVS-LPLDMGSWTSITELNLSTNQLK 388
Cdd:PLN00113 339 LWSNKFSGeIPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSG-NLFKLILFSNSLEGeIPKSLGACRSLRRVRLQDNSFS 417

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  389 -VLPEDIEKLVNLEILVLSNNQLKklpnqiGNLNKLR--------ELDLEENELETVPTEIGfLQHLTKLWVQSNKIL-T 458
Cdd:PLN00113 418 gELPSEFTKLPLVYFLDISNNNLQ------GRINSRKwdmpslqmLSLARNKFFGGLPDSFG-SKRLENLDLSRNQFSgA 490

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 71981152  459 LPRSIGNLCSLQDLRLGENNLTA-IPEEIGHLDSLKSLYLNDNSSLHNLPFELALCQSLEIMSIENSPLS-QIPPEI 533
Cdd:PLN00113 491 VPRKLGSLSELMQLKLSENKLSGeIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSgEIPKNL 567
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
338-532 2.43e-25

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 108.48  E-value: 2.43e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 338 NQISKIPIGIFSKATRLTKLNLKENELVSlpldmgSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQI 417
Cdd:COG4886  82 LSLLLLGLTDLGDLTNLTELDLSGNEELS------NLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPL 155

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 418 GNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQDLRLGENNLTAIPEEIGHLDSLKSLYL 497
Cdd:COG4886 156 GNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDL 235

                       170       180       190
                ....*....|....*....|....*....|....*
gi 71981152 498 NDNsSLHNLPfELALCQSLEIMSIENSPLSQIPPE 532
Cdd:COG4886 236 SNN-QLTDLP-ELGNLTNLEELDLSNNQLTDLPPL 268
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
60-345 2.58e-25

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 110.56  E-value: 2.58e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152   60 RKDLLKEFHKCKEAQDQRLDLSSIEITSIPSPIKEltQLTELFLYKNKLTCLPTEIGQlvNLKKLGLSENALTSLPDSLA 139
Cdd:PRK15370 165 REEAVQRMRDCLKNNKTELRLKILGLTTIPACIPE--QITTLILDNNELKSLPENLQG--NIKTLYANSNQLTSIPATLP 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  140 slESLETLDLRHNKLTEVPSVIykIGSLETLWLRYNRIVAVDEQIGNlsKLKMLDVRENKIRELPSAIGklTSLVVCLVS 219
Cdd:PRK15370 241 --DTIQEMELSINRITELPERL--PSALQSLDLFHNKISCLPENLPE--ELRYLSVYDNSIRTLPAHLP--SGITHLNVQ 312

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  220 YNHLTRVPEEIGdcHSLTQLDLQHNDLSELPYSIGKlvNLVRIGIRYNKIRCIPSELEScqQLEEFIVESNHLQLLPPNL 299
Cdd:PRK15370 313 SNSLTALPETLP--PGLKTLEAGENALTSLPASLPP--ELQVLDVSKNQITVLPETLPP--TITTLDVSRNALTNLPENL 386

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 71981152  300 LTMLPKIHTvnlSRNELTAFPAG-------GPQqfvsTVTINMEHNQISKIPI 345
Cdd:PRK15370 387 PAALQIMQA---SRNNLVRLPESlphfrgeGPQ----PTRIIVEYNPFSERTI 432
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
98-508 5.33e-25

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 107.33  E-value: 5.33e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  98 LTELFLYKNKLTCLPTEIGQLVNLKKLGLSENALTSLPDSLASLESLETLDLRHNKLTEVPSVIYKIGSLETLWLR---- 173
Cdd:COG4886   2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLslll 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 174 YNRIVAVDEQIGNLSKLKMLDVRENKirelpsAIGKLTSLVVCLVSYNHLTRVPEEIGDCHSLTQLDLQHNDLSELPYSI 253
Cdd:COG4886  82 LSLLLLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPL 155

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 254 GKLVNLVRIGIRYNKIRCIPSELESCQQLEEFivesnhlqllppnlltmlpkihtvNLSRNELTAFPAGgpqqfvstvti 333
Cdd:COG4886 156 GNLTNLKSLDLSNNQLTDLPEELGNLTNLKEL------------------------DLSNNQITDLPEP----------- 200

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 334 nmehnqiskipigiFSKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEdIEKLVNLEILVLSNNQLKKL 413
Cdd:COG4886 201 --------------LGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPE-LGNLTNLEELDLSNNQLTDL 265

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 414 PNqIGNLNKLRELD----LEENELETVPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQDLRLGENNLTAIPEEIGHL 489
Cdd:COG4886 266 PP-LANLTNLKTLDlsnnQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSL 344

                       410
                ....*....|....*....
gi 71981152 490 DSLKSLYLNDNSSLHNLPF 508
Cdd:COG4886 345 SLLALLTLLLLLNLLSLLL 363
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
275-539 5.38e-25

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 107.33  E-value: 5.38e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 275 ELESCQQLEEFIVESNHLQLLPPNLLTMLPKIHTVNLSRNELTAfpaggpqQFVSTVTINMEHNQISKIPIGIfSKATRL 354
Cdd:COG4886  67 LLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELS-------NLTNLESLDLSGNQLTDLPEEL-ANLTNL 138

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 355 TKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGNLNKLRELDLEENELE 434
Cdd:COG4886 139 KELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLT 218

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 435 TVPTEIGFLQHLTKLWVQSNKILTLPrSIGNLCSLQDLRLGENNLTAIPEEiGHLDSLKSLYLNDNSSLHNLPFELALCQ 514
Cdd:COG4886 219 DLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPPL-ANLTNLKTLDLSNNQLTDLKLKELELLL 296

                       250       260
                ....*....|....*....|....*
gi 71981152 515 SLEIMSIENSPLSQIPPEITAGGPS 539
Cdd:COG4886 297 GLNSLLLLLLLLNLLELLILLLLLT 321
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
232-491 2.12e-16

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 82.82  E-value: 2.12e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  232 DC--HSLTQLDLQHNDLSELPYSIGKlvNLVRIGIRYNKIRCIPSELEScqQLEEFIVESNHLQLLPPnllTMLPKIHTV 309
Cdd:PRK15370 174 DClkNNKTELRLKILGLTTIPACIPE--QITTLILDNNELKSLPENLQG--NIKTLYANSNQLTSIPA---TLPDTIQEM 246

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  310 NLSRNELTAFPAGGPQqfvSTVTINMEHNQISKIPIGIfskATRLTKLNLKENELVSLPLDMGSwtSITELNLSTNQLKV 389
Cdd:PRK15370 247 ELSINRITELPERLPS---ALQSLDLFHNKISCLPENL---PEELRYLSVYDNSIRTLPAHLPS--GITHLNVQSNSLTA 318

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  390 LPEDIEklVNLEILVLSNNQLKKLPnqiGNLNKLRELDLEENELETVPTEIgFLQHLTKLWVQSNKILTLPRSIGnlCSL 469
Cdd:PRK15370 319 LPETLP--PGLKTLEAGENALTSLP---ASLPPELQVLDVSKNQITVLPET-LPPTITTLDVSRNALTNLPENLP--AAL 390

                        250       260
                 ....*....|....*....|..
gi 71981152  470 QDLRLGENNLTAIPEEIGHLDS 491
Cdd:PRK15370 391 QIMQASRNNLVRLPESLPHFRG 412
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 303-545 3.52e-15

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 79.12  E-value: 3.52e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  303 LPKIHTVNLSRNELTAfpaGGPQQFVSTVT----INMEHNQIS-KIPIGIFSKatrLTKLNLKENELV-SLPLDMGSWTS 376
Cdd:PLN00113  92 LPYIQTINLSNNQLSG---PIPDDIFTTSSslryLNLSNNNFTgSIPRGSIPN---LETLDLSNNMLSgEIPNDIGSFSS 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  377 ITELNLSTNQLK-VLPEDIEKLVNLEILVLSNNQL-KKLPNQIGNL-NKLRELDLEENELETVPTEIGFLQHLTKL-WVQ 452
Cdd:PLN00113 166 LKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLvGQIPRELGQMkSLKWIYLGYNNLSGEIPYEIGGLTSLNHLdLVY 245

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  453 SNKILTLPRSIGNLCSLQDLRLGENNLTA-IPEEIGHLDSLKSLYLNDNSSLHNLPFELALCQSLEIMSIENSPLSQIPP 531
Cdd:PLN00113 246 NNLTGPIPSSLGNLKNLQYLFLYQNKLSGpIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIP 325

                        250
                 ....*....|....
gi 71981152  532 EITAGGPSLVIQYL 545
Cdd:PLN00113 326 VALTSLPRLQVLQL 339
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
332-534 1.45e-14

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 75.74  E-value: 1.45e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 332 TINMEHNQISKIPIGIFSKATRLTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLK 411
Cdd:COG4886   7 SLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLL 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 412 KLPNQIGNLNKLRELDLEEneletvPTEIGFLQHLTKLWVQSNKILTLPRSIGNLCSLQDLRLGENNLTAIPEEIGHLDS 491
Cdd:COG4886  87 LGLTDLGDLTNLTELDLSG------NEELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTN 160

                       170       180       190       200
                ....*....|....*....|....*....|....*....|...
gi 71981152 492 LKSLYLNDNSsLHNLPFELALCQSLEIMSIENSPLSQIPPEIT 534
Cdd:COG4886 161 LKSLDLSNNQ-LTDLPEELGNLTNLKELDLSNNQITDLPEPLG 202
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
271-528 1.58e-11

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 67.11  E-value: 1.58e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  271 CIPSELEScqqleeFIVESNHLQLLPpnllTMLPKIHTVNLSRNELTAFPAGGPqqfvSTVTINMEHNQISKIPigifSK 350
Cdd:PRK15387 219 CLPAHITT------LVIPDNNLTSLP----ALPPELRTLEVSGNQLTSLPVLPP----GLLELSIFSNPLTHLP----AL 280

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  351 ATRLTKLNLKENELVSLPLDMgswTSITELNLSTNQLKVLPEDIEKLVNLEILvlsNNQLKKLPNQIGNLNKLRELDLEE 430
Cdd:PRK15387 281 PSGLCKLWIFGNQLTSLPVLP---PGLQELSVSDNQLASLPALPSELCKLWAY---NNQLTSLPTLPSGLQELSVSDNQL 354

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  431 NELETVPTEigflqhLTKLWVQSNKILTLPRSIGNL-----------------CSLQDLRLGENNLTAIPEEIGHLDSLk 493
Cdd:PRK15387 355 ASLPTLPSE------LYKLWAYNNRLTSLPALPSGLkelivsgnrltslpvlpSELKELMVSGNRLTSLPMLPSGLLSL- 427

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 71981152  494 SLYLNdnsSLHNLPFELALCQSLEIMSIENSPLSQ 528
Cdd:PRK15387 428 SVYRN---QLTRLPESLIHLSSETTVNLEGNPLSE 459
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
60-342 2.02e-10

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 63.64  E-value: 2.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152   60 RKDLLKEFHKCKEAQDQRLDLSSIEITSIPSPIKelTQLTELFLYKNKLTCLPTEIGQlvnLKKLGLSENALTSLPdslA 139
Cdd:PRK15387 188 RAAVVQKMRACLNNGNAVLNVGESGLTTLPDCLP--AHITTLVIPDNNLTSLPALPPE---LRTLEVSGNQLTSLP---V 259

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  140 SLESLETLDLRHNKLTEVPSViykIGSLETLWLRYNRIVAV-------------DEQIGNL----SKLKMLDVRENKIRE 202
Cdd:PRK15387 260 LPPGLLELSIFSNPLTHLPAL---PSGLCKLWIFGNQLTSLpvlppglqelsvsDNQLASLpalpSELCKLWAYNNQLTS 336

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  203 LPSAIGKLTSLVVCLVSYNHLTRVPEEigdchsLTQLDLQHNDLSELPYSIGKLVNLVRIGIRYNKIRCIPSElescqqL 282
Cdd:PRK15387 337 LPTLPSGLQELSVSDNQLASLPTLPSE------LYKLWAYNNRLTSLPALPSGLKELIVSGNRLTSLPVLPSE------L 404

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 71981152  283 EEFIVESNHLQLLPpnlltMLPK-IHTVNLSRNELTAFPAgGPQQFVSTVTINMEHNQISK 342
Cdd:PRK15387 405 KELMVSGNRLTSLP-----MLPSgLLSLSVYRNQLTRLPE-SLIHLSSETTVNLEGNPLSE 459
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
216-500 6.28e-10

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 62.10  E-value: 6.28e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  216 CLVSYNHLTRVPEE----IGDC--HSLTQLDLQHNDLSELPYSIGKLVNLVRIGiryNKIRCIPSELESCQQLEEFIVES 289
Cdd:PRK15387 198 CLNNGNAVLNVGESglttLPDClpAHITTLVIPDNNLTSLPALPPELRTLEVSG---NQLTSLPVLPPGLLELSIFSNPL 274

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  290 NHLQLLPPNLLTMLpkihtvnLSRNELTAFPAGGPqqfvSTVTINMEHNQISKIPigifSKATRLTKLNLKENELVSLP- 368
Cdd:PRK15387 275 THLPALPSGLCKLW-------IFGNQLTSLPVLPP----GLQELSVSDNQLASLP----ALPSELCKLWAYNNQLTSLPt 339

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  369 LDMGswtsITELNLSTNQLKVLPEDIEKLVNLEILvlsNNQLKKLPNQIGNLNKLRELDLEENELETVPTEigflqhLTK 448
Cdd:PRK15387 340 LPSG----LQELSVSDNQLASLPTLPSELYKLWAY---NNRLTSLPALPSGLKELIVSGNRLTSLPVLPSE------LKE 406

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 71981152  449 LWVQSNKILTLPRSIGNLCSLQDLRlgeNNLTAIPEEIGHLDSLKSLYLNDN 500
Cdd:PRK15387 407 LMVSGNRLTSLPMLPSGLLSLSVYR---NQLTRLPESLIHLSSETTVNLEGN 455
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 78-244 8.35e-10

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 59.03  E-value: 8.35e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  78 LDLSSIEITSIPSpIKELTQLTELFLYKNKLTCLPtEIGQLVNLKKLGLSENALTSLpDSLASLESLETLDLRHNKLTEV 157
Cdd:cd21340   7 LYLNDKNITKIDN-LSLCKNLKVLYLYDNKITKIE-NLEFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISVV 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 158 pSVIYKIGSLETLWLRYNRI-----VAVDEQ-IGNLSK-LKMLDVRENKIRELpSAIGKLTSLVVCLVSYNHLTRVPE-- 228
Cdd:cd21340  84 -EGLENLTNLEELHIENQRLppgekLTFDPRsLAALSNsLRVLNISGNNIDSL-EPLAPLRNLEQLDASNNQISDLEEll 161

                       170
                ....*....|....*..
gi 71981152 229 -EIGDCHSLTQLDLQHN 244
Cdd:cd21340 162 dLLSSWPSLRELDLTGN 178
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
354-533 9.84e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 60.72  E-value: 9.84e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 354 LTKLNLKENELVSLPLDMGSWTSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGNLNKLRELDLEENEL 433
Cdd:COG4886   6 LSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLL 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 434 ETVPTEIGFLQHLTKLWVQSNKiltlprSIGNLCSLQDLRLGENNLTAIPEEIGHLDSLKSLYLNDNsSLHNLPFELALC 513
Cdd:COG4886  86 LLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNN-QLTDLPEPLGNL 158

                       170       180
                ....*....|....*....|
gi 71981152 514 QSLEIMSIENSPLSQIPPEI 533
Cdd:COG4886 159 TNLKSLDLSNNQLTDLPEEL 178
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 221-385 5.86e-09

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 56.33  E-value: 5.86e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 221 NHLTRVpEEIGDCHSLTQLDLQHNDLSELPySIGKLVNLVRIGIRYNKIRCIpSELESCQQLEEFIVESnhlQLLPPNlL 300
Cdd:cd21340  34 NKITKI-ENLEFLTNLTHLYLQNNQIEKIE-NLENLVNLKKLYLGGNRISVV-EGLENLTNLEELHIEN---QRLPPG-E 106

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 301 TMLPKIHTVNLSRNELTafpaggpqqfvstvTINMEHNQISKI-PIGIFskaTRLTKLNLKENELVSLP---LDMGSWTS 376
Cdd:cd21340 107 KLTFDPRSLAALSNSLR--------------VLNISGNNIDSLePLAPL---RNLEQLDASNNQISDLEellDLLSSWPS 169


                ....*....
gi 71981152 377 ITELNLSTN 385
Cdd:cd21340 170 LRELDLTGN 178
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
355-541 1.48e-07

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 54.32  E-value: 1.48e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  355 TKLNLKENELVSLPLDMGSwtSITELNLSTNQLKVLPEDIEKlvNLEILVLSNNQLKKLPnqignlnklreldleenelE 434
Cdd:PRK15370 181 TELRLKILGLTTIPACIPE--QITTLILDNNELKSLPENLQG--NIKTLYANSNQLTSIP-------------------A 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  435 TVPTEIGFLQhltklwVQSNKILTLPRSIGNlcSLQDLRLGENNLTAIPEEIGhlDSLKSLYLNDNsSLHNLPFELAlcQ 514
Cdd:PRK15370 238 TLPDTIQEME------LSINRITELPERLPS--ALQSLDLFHNKISCLPENLP--EELRYLSVYDN-SIRTLPAHLP--S 304

                        170       180
                 ....*....|....*....|....*..
gi 71981152  515 SLEIMSIENSPLSQIPPEITAGGPSLV 541
Cdd:PRK15370 305 GITHLNVQSNSLTALPETLPPGLKTLE 331
PLN03150 PLN03150
hypothetical protein; Provisional
 436-501 3.85e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 52.90  E-value: 3.85e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 71981152  436 VPTEIGFLQHLTKLWVQSNKIL-TLPRSIGNLCSLQDLRLGENNLT-AIPEEIGHLDSLKSLYLNDNS 501
Cdd:PLN03150 434 IPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNS 501
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
124-421 3.93e-07

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 52.86  E-value: 3.93e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  124 LGLSENALTSLPDSLASleSLETLDLRHNKLTEVPSVIYKIGSLEtlwLRYNRIVAVDEQIGNLSKLKMLDVRENKIREL 203
Cdd:PRK15387 206 LNVGESGLTTLPDCLPA--HITTLVIPDNNLTSLPALPPELRTLE---VSGNQLTSLPVLPPGLLELSIFSNPLTHLPAL 280

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  204 PSAIGKLtslvvcLVSYNHLTRVPEEIGdchSLTQLDLQHNDLSELPYSIGKLVNLVRIGIRYNKIRCIPSelescqQLE 283
Cdd:PRK15387 281 PSGLCKL------WIFGNQLTSLPVLPP---GLQELSVSDNQLASLPALPSELCKLWAYNNQLTSLPTLPS------GLQ 345

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  284 EFIVESNHLQLLPpnllTMLPKIHTVNLSRNELTAFPAggpqqfvstvtinmehnqiskIPIGifskatrLTKLNLKENE 363
Cdd:PRK15387 346 ELSVSDNQLASLP----TLPSELYKLWAYNNRLTSLPA---------------------LPSG-------LKELIVSGNR 393

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 71981152  364 LVSLPLDMgswTSITELNLSTNQLKVLPEDIEKLVNLEILvlsNNQLKKLPNQIGNLN 421
Cdd:PRK15387 394 LTSLPVLP---SELKELMVSGNRLTSLPMLPSGLLSLSVY---RNQLTRLPESLIHLS 445
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 78-223 4.77e-07

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 52.93  E-value: 4.77e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152   78 LDLSSIEIT-SIPSPIKELTQLTELFLYKNKLTC-LPTEIGQlVNLKKLGLSENALT-SLPDSLASLESLETLDLRHNKL 154
Cdd:PLN00113 433 LDISNNNLQgRINSRKWDMPSLQMLSLARNKFFGgLPDSFGS-KRLENLDLSRNQFSgAVPRKLGSLSELMQLKLSENKL 511

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 71981152  155 T-EVPSVIYKIGSLETLWLRYNRIVA-VDEQIGNLSKLKMLDVRENKIR-ELPSAIGKLTSLVVCLVSYNHL 223
Cdd:PLN00113 512 SgEIPDELSSCKKLVSLDLSHNQLSGqIPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESLVQVNISHNHL 583
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 121-246 6.27e-07

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 52.54  E-value: 6.27e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  121 LKKLGLSENALT-SLPDSLASlESLETLDLRHNKLTE-VPSVIYKIGSLETLWLRYNRIVAV-DEQIGNLSKLKMLDVRE 197
Cdd:PLN00113 454 LQMLSLARNKFFgGLPDSFGS-KRLENLDLSRNQFSGaVPRKLGSLSELMQLKLSENKLSGEiPDELSSCKKLVSLDLSH 532

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 71981152  198 NKIR-ELPSAIGKLTSLVVCLVSYNHLT-RVPEEIGDCHSLTQLDLQHNDL 246
Cdd:PLN00113 533 NQLSgQIPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESLVQVNISHNHL 583
PLN03150 PLN03150
hypothetical protein; Provisional
 184-254 3.70e-06

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 49.81  E-value: 3.70e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 71981152  184 IGNLSKLKMLDVRENKIR-ELPSAIGKLTSLVVCLVSYNHLT-RVPEEIGDCHSLTQLDLQHNDLS-ELPYSIG 254
Cdd:PLN03150 438 ISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSLSgRVPAALG 511
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 120-202 5.19e-06

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 48.51  E-value: 5.19e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 120 NLKKLGLSENALTS-----LPDSLASLESLETLDLRHNKLTEV------PSVIYKIGSLETLWLRYNRI-----VAVDEQ 183
Cdd:cd00116 194 NLEVLDLNNNGLTDegasaLAETLASLKSLEVLNLGDNNLTDAgaaalaSALLSPNISLLTLSLSCNDItddgaKDLAEV 273

                        90
                ....*....|....*....
gi 71981152 184 IGNLSKLKMLDVRENKIRE 202
Cdd:cd00116 274 LAEKESLLELDLRGNKFGE 292
LRR_8 pfam13855
Leucine rich repeat;
120-177 6.68e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 43.67  E-value: 6.68e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152   120 NLKKLGLSENALTSL-PDSLASLESLETLDLRHNKLTEV-PSVIYKIGSLETLWLRYNRI 177
Cdd:pfam13855   2 NLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
96-154 1.26e-05

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.90  E-value: 1.26e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 71981152    96 TQLTELFLYKNKLTCLPTEI-GQLVNLKKLGLSENALTSL-PDSLASLESLETLDLRHNKL 154
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 111-208 1.58e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 47.89  E-value: 1.58e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  111 LPTEIGQLVNLKKLGLSENALT-SLPDSLASLESLETLDLRHNKLTevpsviykiGSletlwlrynrivaVDEQIGNLSK 189
Cdd:PLN03150 434 IPNDISKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFN---------GS-------------IPESLGQLTS 491

                         90       100
                 ....*....|....*....|
gi 71981152  190 LKMLDVRENKIR-ELPSAIG 208
Cdd:PLN03150 492 LRILNLNGNSLSgRVPAALG 511
PLN03150 PLN03150
hypothetical protein; Provisional
 349-418 1.14e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 44.81  E-value: 1.14e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 71981152  349 SKATRLTKLNLKENELV-SLPLDMGSWTSITELNLSTNQLK-VLPEDIEKLVNLEILVLSNNQLK-KLPNQIG 418
Cdd:PLN03150 439 SKLRHLQSINLSGNSIRgNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSLSgRVPAALG 511
LRR_8 pfam13855
Leucine rich repeat;
352-410 1.92e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 39.43  E-value: 1.92e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 71981152   352 TRLTKLNLKENELVSLPLDM-GSWTSITELNLSTNQLKVL-PEDIEKLVNLEILVLSNNQL 410
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PLN03210 PLN03210
Resistant to P. syringae 6; Provisional
 97-415 3.13e-04

Resistant to P. syringae 6; Provisional


Pssm-ID: 215633 [Multi-domain]  Cd Length: 1153  Bit Score: 43.71  E-value: 3.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152    97 QLTELFLYKNKLTCLPTEIgQLVNLKKLGLSENALTSLPDSLASLESLETLDLRHNK-LTEVPSViykigSLETlwlryn 175
Cdd:PLN03210  590 KLRLLRWDKYPLRCMPSNF-RPENLVKLQMQGSKLEKLWDGVHSLTGLRNIDLRGSKnLKEIPDL-----SMAT------ 657

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152   176 rivavdeqigNLSKLKMLDVreNKIRELPSAIGKLTSLVVCLVSY-NHLTRVPEEIgDCHSLTQLDLqhNDLSELPYSIG 254
Cdd:PLN03210  658 ----------NLETLKLSDC--SSLVELPSSIQYLNKLEDLDMSRcENLEILPTGI-NLKSLYRLNL--SGCSRLKSFPD 722

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152   255 KLVNLVRIGIRYNKIRCIPSELEsCQQLEEFIV---ESNHL----QLLPPnLLTML-PKIHTVNLSRN-ELTAFPAGgPQ 325
Cdd:PLN03210  723 ISTNISWLDLDETAIEEFPSNLR-LENLDELILcemKSEKLwervQPLTP-LMTMLsPSLTRLFLSDIpSLVELPSS-IQ 799

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152   326 QFVSTVTINMEH-NQISKIPIGIFSKAtrLTKLNLKE-NELVSLPlDMGswTSITELNLSTNQLKVLPEDIEKLVNLEIL 403
Cdd:PLN03210  800 NLHKLEHLEIENcINLETLPTGINLES--LESLDLSGcSRLRTFP-DIS--TNISDLNLSRTGIEEVPWWIEKFSNLSFL 874

                         330
                  ....*....|....
gi 71981152   404 VLS--NNQLKKLPN 415
Cdd:PLN03210  875 DMNgcNNLQRVSLN 888
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 375-529 3.97e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 42.08  E-value: 3.97e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 375 TSITELNLSTNQLKVLpEDIEKLVNLEILVLSNNQLKKLPNqignlnklreldleeneletvpteIGFLQHLTKLWVQSN 454
Cdd:cd21340   2 KRITHLYLNDKNITKI-DNLSLCKNLKVLYLYDNKITKIEN------------------------LEFLTNLTHLYLQNN 56

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 455 KILTLPrSIGNLCSLQDLRLGENNLTAIpEEIGHLDSLKSLYLNDNSSLHNLPFE------LALCQSLEIMSIENSPLSQ 528
Cdd:cd21340  57 QIEKIE-NLENLVNLKKLYLGGNRISVV-EGLENLTNLEELHIENQRLPPGEKLTfdprslAALSNSLRVLNISGNNIDS 134


                .
gi 71981152 529 I 529
Cdd:cd21340 135 L 135
LRR_8 pfam13855
Leucine rich repeat;
166-246 5.40e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 38.27  E-value: 5.40e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152   166 SLETLWLRYNRIVAV-DEQIGNLSKLKMLDVRENKIRELPsaigkltslvvclvsynhltrvPEEIGDCHSLTQLDLQHN 244
Cdd:pfam13855   2 NLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLS----------------------PGAFSGLPSLRYLDLSGN 59


                  ..
gi 71981152   245 DL 246
Cdd:pfam13855  60 RL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 95-194 5.99e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 41.31  E-value: 5.99e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152  95 LTQLTELFLYKNKL---TCL---P-TEIGQLVNLKKLGLSENALTSLpDSLASLESLETLDLRHNKLT---EVPSVIYKI 164
Cdd:cd21340  89 LTNLEELHIENQRLppgEKLtfdPrSLAALSNSLRVLNISGNNIDSL-EPLAPLRNLEQLDASNNQISdleELLDLLSSW 167

                        90       100       110
                ....*....|....*....|....*....|....
gi 71981152 165 GSLETLWLRYNRIVAV----DEQIGNLSKLKMLD 194
Cdd:cd21340 168 PSLRELDLTGNPVCKKpkyrDKIILASKSLEVLD 201
LRR_8 pfam13855
Leucine rich repeat;
444-500 7.62e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.89  E-value: 7.62e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 71981152   444 QHLTKLWVQSNKILTL-PRSIGNLCSLQDLRLGENNLTAI-PEEIGHLDSLKSLYLNDN 500
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGN 59
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 333-500 9.20e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 40.92  E-value: 9.20e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 333 INMEHNQISKIpiGIFSKATRLTKLNLKENELVSLPlDMGSWTSITELNLSTNQLKVLpEDIEKLVNLEILVLSNNQLKK 412
Cdd:cd21340   7 LYLNDKNITKI--DNLSLCKNLKVLYLYDNKITKIE-NLEFLTNLTHLYLQNNQIEKI-ENLENLVNLKKLYLGGNRISV 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 413 lpnqIGNLNKLRELDLEENELETVPTEIGFL----------QHLTKLWVQSNKILTLpRSIGNLCSLQDLRLGENNLTAI 482
Cdd:cd21340  83 ----VEGLENLTNLEELHIENQRLPPGEKLTfdprslaalsNSLRVLNISGNNIDSL-EPLAPLRNLEQLDASNNQISDL 157

                       170       180
                ....*....|....*....|.
gi 71981152 483 PE---EIGHLDSLKSLYLNDN 500
Cdd:cd21340 158 EElldLLSSWPSLRELDLTGN 178
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
375-533 1.53e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 41.07  E-value: 1.53e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 375 TSITELNLSTNQLKVLPEDIEKLVNLEILVLSNNQLKKLPNQIGNLNKLRELDLEENELETVPTEIGFLQHLTKLWVQSN 454
Cdd:COG4886   4 LLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLS 83

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 71981152 455 KILTLPRSIGNLCSLQDLRLGENNltaipeEIGHLDSLKSLYLNDNsSLHNLPFELALCQSLEIMSIENSPLSQIPPEI 533
Cdd:COG4886  84 LLLLGLTDLGDLTNLTELDLSGNE------ELSNLTNLESLDLSGN-QLTDLPEELANLTNLKELDLSNNQLTDLPEPL 155
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 121-248 7.90e-03

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 38.49  E-value: 7.90e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71981152 121 LKKLGLSENAL-----TSLPDSLASLESLETLDLRHNKLTEvpsviykIGsletlwlrynrIVAVDEQIGNLSKLKMLDV 195
Cdd:cd00116 167 LKELNLANNGIgdagiRALAEGLKANCNLEVLDLNNNGLTD-------EG-----------ASALAETLASLKSLEVLNL 228

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 71981152 196 RENKIRELPSA------IGKLTSLVVCLVSYNHLTR-----VPEEIGDCHSLTQLDLQHNDLSE 248
Cdd:cd00116 229 GDNNLTDAGAAalasalLSPNISLLTLSLSCNDITDdgakdLAEVLAEKESLLELDLRGNKFGE 292
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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