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Conserved domains on  [gi|67763828|ref|NP_001020017|]
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zinc finger protein 62 isoform 2 [Mus musculus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
430-843 4.71e-11

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 66.26  E-value: 4.71e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 430 RPYVCDVCGKTFRNNSGLKVHRRLHTGEKPYKCDV--CGKAYISRSSLKNHKGIHMGEKPYKCSYCEKSFNYSSALEQHK 507
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLS 111

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 508 R-IHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEEC------GKAYISLSSLINHKSVHPGEKPFKCDECEKA 580
Cdd:COG5048 112 SsSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnsssvnTPQSNSLHPPLPANSLSKDPSSNLSLLISSN 191

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 581 FITyrTLLNHKKIHLGEKPYKCDVC---EKSFNYTSLLSQHKRVHTREKPFecDRCEKVFRNNSSLKVHKRIHtgekpYE 657
Cdd:COG5048 192 VST--SIPSSSENSPLSSSYSIPSSssdQNLENSSSSLPLTTNSQLSPKSL--LSQSPSSLSSSDSSSSASES-----PR 262

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 658 CDICGKAYISHSSLINHKSTHPGKT-SYTCDECGKAFFSSRTLISHKR--VHLGE--KPFKCVE--CGKSFSYSSLLSQH 730
Cdd:COG5048 263 SSLPTASSQSSSPNESDSSSEKGFSlPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRH 342

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 731 KRIHTGEKPYVCDWC-------GKAFRNSSGLTVHKRIHTGEKPYGCD--ECEKAYISHSSLINHKSVHRGKQPYNCE-- 799
Cdd:COG5048 343 ILLHTSISPAKEKLLnssskfsPLLNNEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKnp 422

                       410       420       430       440
                ....*....|....*....|....*....|....*....|....*
gi 67763828 800 -CGKSFNYRSVLDQHKRIHTGKKPYRCNDCGKaFNIRSNLTKHKR 843
Cdd:COG5048 423 pCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 372-451 5.55e-09

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 59.35  E-value: 5.55e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 372 GEKPYKCDI--CGKAFSYSSGLAVHK-SIHPGKKAHECKDCGKsfsynslllqHKTIHTGERPYVCDVCGKTFRNNSGLK 448
Cdd:COG5189 346 DGKPYKCPVegCNKKYKNQNGLKYHMlHGHQNQKLHENPSPEK----------MNIFSAKDKPYRCEVCDKRYKNLNGLK 415


                ...
gi 67763828 449 VHR 451
Cdd:COG5189 416 YHR 418
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
120-535 2.34e-07

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 54.32  E-value: 2.34e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 120 DKKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYEC--DDCRGTFRSSSSLRVHKRIHTGEKPYKCDECGKAYMSY--SSL 195
Cdd:COG5048  30 APRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKasSSS 109

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 196 INHKSTHS--GEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHtgekpyecdTCGKTF 273
Cdd:COG5048 110 LSSSSSNSndNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---------SLSKDP 180

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 274 SNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDEC 353
Cdd:COG5048 181 SSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASES 260

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 354 GKAFRNSSGLIVHKRIHTGE-------KPYKCDICGKAFSYSSGLAVHK--SIHPGK--KAHEC--KDCGKSFSYNSLLL 420
Cdd:COG5048 261 PRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCpySLCGKLFSRNDALK 340

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 421 QHKTIHTGERPYVCDVCGKTFRNNSGLK-------VHRRLHTGEKPYKCDV--CGKAYISRSSLKNHKGIHMGEKP--YK 489
Cdd:COG5048 341 RHILLHTSISPAKEKLLNSSSKFSPLLNneppqslQQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPynCK 420

                       410       420       430       440
                ....*....|....*....|....*....|....*....|....*.
gi 67763828 490 CSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHK 535
Cdd:COG5048 421 NPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
430-843 4.71e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 66.26  E-value: 4.71e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 430 RPYVCDVCGKTFRNNSGLKVHRRLHTGEKPYKCDV--CGKAYISRSSLKNHKGIHMGEKPYKCSYCEKSFNYSSALEQHK 507
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLS 111

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 508 R-IHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEEC------GKAYISLSSLINHKSVHPGEKPFKCDECEKA 580
Cdd:COG5048 112 SsSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnsssvnTPQSNSLHPPLPANSLSKDPSSNLSLLISSN 191

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 581 FITyrTLLNHKKIHLGEKPYKCDVC---EKSFNYTSLLSQHKRVHTREKPFecDRCEKVFRNNSSLKVHKRIHtgekpYE 657
Cdd:COG5048 192 VST--SIPSSSENSPLSSSYSIPSSssdQNLENSSSSLPLTTNSQLSPKSL--LSQSPSSLSSSDSSSSASES-----PR 262

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 658 CDICGKAYISHSSLINHKSTHPGKT-SYTCDECGKAFFSSRTLISHKR--VHLGE--KPFKCVE--CGKSFSYSSLLSQH 730
Cdd:COG5048 263 SSLPTASSQSSSPNESDSSSEKGFSlPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRH 342

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 731 KRIHTGEKPYVCDWC-------GKAFRNSSGLTVHKRIHTGEKPYGCD--ECEKAYISHSSLINHKSVHRGKQPYNCE-- 799
Cdd:COG5048 343 ILLHTSISPAKEKLLnssskfsPLLNNEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKnp 422

                       410       420       430       440
                ....*....|....*....|....*....|....*....|....*
gi 67763828 800 -CGKSFNYRSVLDQHKRIHTGKKPYRCNDCGKaFNIRSNLTKHKR 843
Cdd:COG5048 423 pCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 372-451 5.55e-09

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 59.35  E-value: 5.55e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 372 GEKPYKCDI--CGKAFSYSSGLAVHK-SIHPGKKAHECKDCGKsfsynslllqHKTIHTGERPYVCDVCGKTFRNNSGLK 448
Cdd:COG5189 346 DGKPYKCPVegCNKKYKNQNGLKYHMlHGHQNQKLHENPSPEK----------MNIFSAKDKPYRCEVCDKRYKNLNGLK 415


                ...
gi 67763828 449 VHR 451
Cdd:COG5189 416 YHR 418
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
120-535 2.34e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 54.32  E-value: 2.34e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 120 DKKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYEC--DDCRGTFRSSSSLRVHKRIHTGEKPYKCDECGKAYMSY--SSL 195
Cdd:COG5048  30 APRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKasSSS 109

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 196 INHKSTHS--GEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHtgekpyecdTCGKTF 273
Cdd:COG5048 110 LSSSSSNSndNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---------SLSKDP 180

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 274 SNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDEC 353
Cdd:COG5048 181 SSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASES 260

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 354 GKAFRNSSGLIVHKRIHTGE-------KPYKCDICGKAFSYSSGLAVHK--SIHPGK--KAHEC--KDCGKSFSYNSLLL 420
Cdd:COG5048 261 PRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCpySLCGKLFSRNDALK 340

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 421 QHKTIHTGERPYVCDVCGKTFRNNSGLK-------VHRRLHTGEKPYKCDV--CGKAYISRSSLKNHKGIHMGEKP--YK 489
Cdd:COG5048 341 RHILLHTSISPAKEKLLNSSSKFSPLLNneppqslQQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPynCK 420

                       410       420       430       440
                ....*....|....*....|....*....|....*....|....*.
gi 67763828 490 CSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHK 535
Cdd:COG5048 421 NPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 486-534 3.83e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 39.85  E-value: 3.83e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 67763828 486 KPYkCSYCEKSFNYSSALEQHKRIHTrekpFGCDECGKAFRNNSGLKVH 534
Cdd:cd20908   1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-H2C2_2 pfam13465
Zinc-finger double domain;
279-303 3.91e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.91e-04
                          10        20
                  ....*....|....*....|....*
gi 67763828   279 LRVHKRIHTGEKPYECDECGKAFIT 303
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
363-387 1.46e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.46e-03
                          10        20
                  ....*....|....*....|....*
gi 67763828   363 LIVHKRIHTGEKPYKCDICGKAFSY 387
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
810-833 1.53e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.53e-03
                          10        20
                  ....*....|....*....|....
gi 67763828   810 LDQHKRIHTGKKPYRCNDCGKAFN 833
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 346-394 2.34e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 37.92  E-value: 2.34e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 67763828 346 KPYeCDECGKAFRNSSGLIVHKRIHTgekpYKCDICGKAFSYSSGLAVH 394
Cdd:cd20908   1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
430-843 4.71e-11

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 66.26  E-value: 4.71e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 430 RPYVCDVCGKTFRNNSGLKVHRRLHTGEKPYKCDV--CGKAYISRSSLKNHKGIHMGEKPYKCSYCEKSFNYSSALEQHK 507
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSLS 111

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 508 R-IHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEEC------GKAYISLSSLINHKSVHPGEKPFKCDECEKA 580
Cdd:COG5048 112 SsSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNnsssvnTPQSNSLHPPLPANSLSKDPSSNLSLLISSN 191

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 581 FITyrTLLNHKKIHLGEKPYKCDVC---EKSFNYTSLLSQHKRVHTREKPFecDRCEKVFRNNSSLKVHKRIHtgekpYE 657
Cdd:COG5048 192 VST--SIPSSSENSPLSSSYSIPSSssdQNLENSSSSLPLTTNSQLSPKSL--LSQSPSSLSSSDSSSSASES-----PR 262

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 658 CDICGKAYISHSSLINHKSTHPGKT-SYTCDECGKAFFSSRTLISHKR--VHLGE--KPFKCVE--CGKSFSYSSLLSQH 730
Cdd:COG5048 263 SSLPTASSQSSSPNESDSSSEKGFSlPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRH 342

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 731 KRIHTGEKPYVCDWC-------GKAFRNSSGLTVHKRIHTGEKPYGCD--ECEKAYISHSSLINHKSVHRGKQPYNCE-- 799
Cdd:COG5048 343 ILLHTSISPAKEKLLnssskfsPLLNNEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKnp 422

                       410       420       430       440
                ....*....|....*....|....*....|....*....|....*
gi 67763828 800 -CGKSFNYRSVLDQHKRIHTGKKPYRCNDCGKaFNIRSNLTKHKR 843
Cdd:COG5048 423 pCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
317-759 4.74e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 62.79  E-value: 4.74e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 317 DKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYEC--DECGKAFRNSSGLIVHKRIHTGEKPYKCDICGKafSYSSGLAVH 394
Cdd:COG5048  31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLP--LSNSKASSS 108

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 395 KSIHpgkkaheckdCGKSFSYNSLLLQHKTIHTGERPYVCDVCGKTFRNNSGLKVHRRLHTgekpyKCDVCGKAYISRSS 474
Cdd:COG5048 109 SLSS----------SSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSV-----NTPQSNSLHPPLPA 173

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 475 LKNHKGIHMGEKPYKCSycEKSFNYSSALEQHKRIHTREKPFGCDECGKaFRNNSGLKVHKRIHTGERPYKCEecgkayi 554
Cdd:COG5048 174 NSLSKDPSSNLSLLISS--NVSTSIPSSSENSPLSSSYSIPSSSSDQNL-ENSSSSLPLTTNSQLSPKSLLSQ------- 243

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 555 slssliNHKSVHPGEKPFKCDECEKAFITYRTLLNHKKIHLGE-------KPYKCDVCEKSFNYTSLLSQHKR--VHTRE 625
Cdd:COG5048 244 ------SPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGE 317

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 626 --KPFECD--RCEKVFRNNSSLKVHKRIHTGEKPYECDIC--------GKAYISHSSLINHKSTHPGKTSYTCDECGKAF 693
Cdd:COG5048 318 slKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEKLLnssskfspLLNNEPPQSLQQYKDLKNDKKSETLSNSCIRN 397

                       410       420       430       440       450       460
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 67763828 694 FSSR-TLISHKRVHLGEKP--FKCVECGKSFSYSSLLSQHKRIHTGEKPYVCDWCGKAFRNSSGLTVHK 759
Cdd:COG5048 398 FKRDsNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 372-451 5.55e-09

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 59.35  E-value: 5.55e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 372 GEKPYKCDI--CGKAFSYSSGLAVHK-SIHPGKKAHECKDCGKsfsynslllqHKTIHTGERPYVCDVCGKTFRNNSGLK 448
Cdd:COG5189 346 DGKPYKCPVegCNKKYKNQNGLKYHMlHGHQNQKLHENPSPEK----------MNIFSAKDKPYRCEVCDKRYKNLNGLK 415


                ...
gi 67763828 449 VHR 451
Cdd:COG5189 416 YHR 418
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 451-535 2.06e-08

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 57.42  E-value: 2.06e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 451 RRLHT-GEKPYKCDV--CGKAYISRSSLKNHKgihmgekpyKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRN 527
Cdd:COG5189 340 RMLKVkDGKPYKCPVegCNKKYKNQNGLKYHM---------LHGHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKN 410


                ....*...
gi 67763828 528 NSGLKVHK 535
Cdd:COG5189 411 LNGLKYHR 418
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
262-648 8.81e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.86  E-value: 8.81e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 262 KPYECDTCGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSI------------------HFGDKPYKCD 323
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSRHLrthhnnpsdlnskslplsNSKASSSSLS 111

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 324 ECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTGEK-------PYKCDICGKAFSYSSGLAVHKS 396
Cdd:COG5048 112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPqsnslhpPLPANSLSKDPSSNLSLLISSN 191

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 397 IHPGKKAHECKDCGKSFSYNSLLLQHKTIHTGERPYVCDVCGKTFRNNSGLKVHRRLHTGEKPYKCDVCGKAYISRSSLK 476
Cdd:COG5048 192 VSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQ 271

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 477 NHKGIHMGE-------KPYKCSYCEKSFNYSSALEQHKR--IHTRE--KPFGCDE--CGKAFRNNSGLKVHKRIHTGERP 543
Cdd:COG5048 272 SSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 544 YKC--EECGKAYISLSSLINHKSVHP-----GEKPFKCD--ECEKAFITYRTLLNHKKIHLGEKP--YKCDVCEKSFNYT 612
Cdd:COG5048 352 AKEklLNSSSKFSPLLNNEPPQSLQQykdlkNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRH 431

                       410       420       430
                ....*....|....*....|....*....|....*.
gi 67763828 613 SLLSQHKRVHTREKPFECdRCEKVFRNNSSLKVHKR 648
Cdd:COG5048 432 YNLIPHKKIHTNHAPLLC-SILKSFRRDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
178-583 1.04e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.47  E-value: 1.04e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 178 KPYKCDECGKAYMSYSSLINHKSTHSGEKNCKC--DECGKSFNYSSVLDQHKRIHTGEKPYECgeCGKAFRNSSGLRVHK 255
Cdd:COG5048  32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLN--SKSLPLSNSKASSSS 109

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 256 RIHTGEKP-YECDTCGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHfgDKPYKCdECEKSFNYSSL 334
Cdd:COG5048 110 LSSSSSNSnDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHP--PLPANS-LSKDPSSNLSL 186

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 335 LIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTgEKPYKCDICGKAFSYSSGLAVHKSIHPGKKAHECKDCGKSFS 414
Cdd:COG5048 187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENS-SSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSL 265

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 415 YNSLLLQHKTIHTGER-------PYVCDVCGKTFRNNSGLKVHRR--LHTGE--KPYKCDV--CGKAYISRSSLKNHKGI 481
Cdd:COG5048 266 PTASSQSSSPNESDSSsekgfslPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILL 345

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 482 HMGEKPYKCSYCEKSFNYSSAL-------EQHKRIHTREKPFGCD--ECGKAFRNNSGLKVHKRIHTGERP--YKCEECG 550
Cdd:COG5048 346 HTSISPAKEKLLNSSSKFSPLLnneppqsLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCS 425

                       410       420       430
                ....*....|....*....|....*....|...
gi 67763828 551 KAYISLSSLINHKSVHPGEKPFKCDECEKAFIT 583
Cdd:COG5048 426 KSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRD 458
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
120-535 2.34e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 54.32  E-value: 2.34e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 120 DKKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYEC--DDCRGTFRSSSSLRVHKRIHTGEKPYKCDECGKAYMSY--SSL 195
Cdd:COG5048  30 APRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKasSSS 109

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 196 INHKSTHS--GEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHtgekpyecdTCGKTF 273
Cdd:COG5048 110 LSSSSSNSndNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSNSLHPPLPAN---------SLSKDP 180

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 274 SNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDEC 353
Cdd:COG5048 181 SSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASES 260

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 354 GKAFRNSSGLIVHKRIHTGE-------KPYKCDICGKAFSYSSGLAVHK--SIHPGK--KAHEC--KDCGKSFSYNSLLL 420
Cdd:COG5048 261 PRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCpySLCGKLFSRNDALK 340

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 421 QHKTIHTGERPYVCDVCGKTFRNNSGLK-------VHRRLHTGEKPYKCDV--CGKAYISRSSLKNHKGIHMGEKP--YK 489
Cdd:COG5048 341 RHILLHTSISPAKEKLLNSSSKFSPLLNneppqslQQYKDLKNDKKSETLSnsCIRNFKRDSNLSLHIITHLSFRPynCK 420

                       410       420       430       440
                ....*....|....*....|....*....|....*....|....*.
gi 67763828 490 CSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHK 535
Cdd:COG5048 421 NPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 428-480 4.25e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.10  E-value: 4.25e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 67763828 428 GERPYVCDV--CGKTFRNNSGLKVHRrLH--------------------TGEKPYKCDVCGKAYISRSSLKNHKG 480
Cdd:COG5189 346 DGKPYKCPVegCNKKYKNQNGLKYHM-LHghqnqklhenpspekmnifsAKDKPYRCEVCDKRYKNLNGLKYHRK 419
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 232-283 1.04e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 45.86  E-value: 1.04e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 67763828 232 GEKPYECG--ECGKAFRNSSGLRVHKR-------------------IHTGEKPYECDTCGKTFSNSSGLRVHK 283
Cdd:COG5189 346 DGKPYKCPveGCNKKYKNQNGLKYHMLhghqnqklhenpspekmniFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 43-255 3.18e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 44.32  E-value: 3.18e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828  43 FPKWKILKEGKSSIREM---IDT-HTNAANIKLEQDDETSEKSFYPSTNTMHQTIPTEPNCTKQGEHTENING----NVH 114
Cdd:COG5189 214 LKKLSLIEEKKFPERVRsryIDIgHMMDTHQFYLEDVDLMDDDILGPSNEEMLYKYISPSQGSAELFEESSLGfdyeFIH 293

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 115 PA----HIADKKLHKCDECGKSFKYNSRLVQHKIMHTGEKryecddcrgTFRSSSSLRVHKrihtGEKPYKCD--ECGKA 188
Cdd:COG5189 294 KSvgnkEIRGGISTGEMIDVRKLPCTNSSSNGKLAHGGER---------NIDTPSRMLKVK----DGKPYKCPveGCNKK 360

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 67763828 189 YMSYSSLINHKsthsgekncKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHK 255
Cdd:COG5189 361 YKNQNGLKYHM---------LHGHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 486-534 3.83e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 39.85  E-value: 3.83e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 67763828 486 KPYkCSYCEKSFNYSSALEQHKRIHTrekpFGCDECGKAFRNNSGLKVH 534
Cdd:cd20908   1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-H2C2_2 pfam13465
Zinc-finger double domain;
279-303 3.91e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.51  E-value: 3.91e-04
                          10        20
                  ....*....|....*....|....*
gi 67763828   279 LRVHKRIHTGEKPYECDECGKAFIT 303
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
251-275 8.57e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 8.57e-04
                          10        20
                  ....*....|....*....|....*
gi 67763828   251 LRVHKRIHTGEKPYECDTCGKTFSN 275
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
166-189 1.14e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 1.14e-03
                          10        20
                  ....*....|....*....|....
gi 67763828   166 SLRVHKRIHTGEKPYKCDECGKAY 189
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
223-247 1.33e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 1.33e-03
                          10        20
                  ....*....|....*....|....*
gi 67763828   223 LDQHKRIHTGEKPYECGECGKAFRN 247
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
363-387 1.46e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.46e-03
                          10        20
                  ....*....|....*....|....*
gi 67763828   363 LIVHKRIHTGEKPYKCDICGKAFSY 387
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
810-833 1.53e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.53e-03
                          10        20
                  ....*....|....*....|....
gi 67763828   810 LDQHKRIHTGKKPYRCNDCGKAFN 833
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFK 25
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 483-563 1.73e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.01  E-value: 1.73e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 483 MGEKPYKCSY--CEKSFNYSSALEQHkRIHTREKPfgcdecgKAFRNNSGLKvHKRIHTGERPYKCEECGKAYISLSSLI 560
Cdd:COG5189 345 KDGKPYKCPVegCNKKYKNQNGLKYH-MLHGHQNQ-------KLHENPSPEK-MNIFSAKDKPYRCEVCDKRYKNLNGLK 415


                ...
gi 67763828 561 NHK 563
Cdd:COG5189 416 YHR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
642-667 2.16e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 2.16e-03
                          10        20
                  ....*....|....*....|....*.
gi 67763828   642 SLKVHKRIHTGEKPYECDICGKAYIS 667
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 346-394 2.34e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 37.92  E-value: 2.34e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 67763828 346 KPYeCDECGKAFRNSSGLIVHKRIHTgekpYKCDICGKAFSYSSGLAVH 394
Cdd:cd20908   1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-H2C2_2 pfam13465
Zinc-finger double domain;
531-555 2.43e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.20  E-value: 2.43e-03
                          10        20
                  ....*....|....*....|....*
gi 67763828   531 LKVHKRIHTGERPYKCEECGKAYIS 555
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 595-675 5.99e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.09  E-value: 5.99e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 67763828 595 LGEKPYKCDV--CEKSFNYTSLLSQHkRVHtrekpfecDRCEKVFRNNSSLKVHKRIHTGEKPYECDICGKAYISHSSLI 672
Cdd:COG5189 345 KDGKPYKCPVegCNKKYKNQNGLKYH-MLH--------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLK 415


                ...
gi 67763828 673 NHK 675
Cdd:COG5189 416 YHR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
335-359 6.61e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 6.61e-03
                          10        20
                  ....*....|....*....|....*
gi 67763828   335 LIQHKVIHTGEKPYECDECGKAFRN 359
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
447-471 7.01e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 7.01e-03
                          10        20
                  ....*....|....*....|....*
gi 67763828   447 LKVHRRLHTGEKPYKCDVCGKAYIS 471
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 707-759 9.38e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 39.32  E-value: 9.38e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 67763828 707 LGEKPFKC--VECGKSFSYSSLLSQHKR-------------------IHTGEKPYVCDWCGKAFRNSSGLTVHK 759
Cdd:COG5189 345 KDGKPYKCpvEGCNKKYKNQNGLKYHMLhghqnqklhenpspekmniFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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