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Conserved domains on  [gi|1024336636|gb|KZX33285|]
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competence protein ComGF [Staphylococcus aureus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
pilin_ComGF super family cl49146
competence type IV pilus minor pilin ComGF; ComGF is one of several minor pilins in the type ...
 1-114 2.85e-07

competence type IV pilus minor pilin ComGF; ComGF is one of several minor pilins in the type IV pilus involved in the competence system of natural transformation by various Gram-positive bacteria. Oddly, while nearly all members have an N-terminal region with a consensus site for cleavage and methylation, ComGF from Bacillus subtilis appears N-terminally truncated, and may be functional despite the truncation.


The actual alignment was detected with superfamily member NF041002:

Pssm-ID: 468931 [Multi-domain]  Cd Length: 138  Bit Score: 46.07  E-value: 2.85e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024336636   1 MVISITLLIVPDLIRLNKTFLIESRELTTVDFEFFSRDILEDFKGVDRN--DIEIRQQRIILHKGEEMIEYKLINNKIIK 78
Cdd:NF041002   14 LVLSLILLLIPLLIKLLLKVEQYLNNSDQLEWLLFLQQLESELKESTFKvkNNKLYVKLDLIKSNGKTVAYEKYNSDIRK 93

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1024336636  79 VVNDRGNITMINNVTAFTANIYYKSiIKITITVKVG 114
Cdd:NF041002   94 RVNGKGHQPLLQGVKSVSFSQKNNQ-VTIKVTFENG 128
 
Name Accession Description Interval E-value
pilin_ComGF NF041002
competence type IV pilus minor pilin ComGF; ComGF is one of several minor pilins in the type ...
 1-114 2.85e-07

competence type IV pilus minor pilin ComGF; ComGF is one of several minor pilins in the type IV pilus involved in the competence system of natural transformation by various Gram-positive bacteria. Oddly, while nearly all members have an N-terminal region with a consensus site for cleavage and methylation, ComGF from Bacillus subtilis appears N-terminally truncated, and may be functional despite the truncation.


Pssm-ID: 468931 [Multi-domain]  Cd Length: 138  Bit Score: 46.07  E-value: 2.85e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024336636   1 MVISITLLIVPDLIRLNKTFLIESRELTTVDFEFFSRDILEDFKGVDRN--DIEIRQQRIILHKGEEMIEYKLINNKIIK 78
Cdd:NF041002   14 LVLSLILLLIPLLIKLLLKVEQYLNNSDQLEWLLFLQQLESELKESTFKvkNNKLYVKLDLIKSNGKTVAYEKYNSDIRK 93

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1024336636  79 VVNDRGNITMINNVTAFTANIYYKSiIKITITVKVG 114
Cdd:NF041002   94 RVNGKGHQPLLQGVKSVSFSQKNNQ-VTIKVTFENG 128
ComGF pfam15980
Putative Competence protein ComGF; ComGF is a family of putative bacterial competence proteins.
 23-115 7.51e-03

Putative Competence protein ComGF; ComGF is a family of putative bacterial competence proteins.


Pssm-ID: 435051  Cd Length: 99  Bit Score: 33.43  E-value: 7.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024336636  23 ESRELTTVDFEFFSRDILEDFKGVDrnDIEIRQQRIILHKGEE-MIEYKLINNKIIKVVNDRGNITMINNVTAFtaNIYY 101
Cdd:pfam15980   8 ELQNNNQIEWQLFLIQLENELKESK--LVKVEGNKLFYVKKEGdTITYEKYNNKIRRRVNGGGYQPLLQNVKNV--QFEQ 83

                          90
                  ....*....|....*
gi 1024336636 102 KS-IIKITITVKVGT 115
Cdd:pfam15980  84 ENnLVYITVTFKNGE 98
 
Name Accession Description Interval E-value
pilin_ComGF NF041002
competence type IV pilus minor pilin ComGF; ComGF is one of several minor pilins in the type ...
 1-114 2.85e-07

competence type IV pilus minor pilin ComGF; ComGF is one of several minor pilins in the type IV pilus involved in the competence system of natural transformation by various Gram-positive bacteria. Oddly, while nearly all members have an N-terminal region with a consensus site for cleavage and methylation, ComGF from Bacillus subtilis appears N-terminally truncated, and may be functional despite the truncation.


Pssm-ID: 468931 [Multi-domain]  Cd Length: 138  Bit Score: 46.07  E-value: 2.85e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024336636   1 MVISITLLIVPDLIRLNKTFLIESRELTTVDFEFFSRDILEDFKGVDRN--DIEIRQQRIILHKGEEMIEYKLINNKIIK 78
Cdd:NF041002   14 LVLSLILLLIPLLIKLLLKVEQYLNNSDQLEWLLFLQQLESELKESTFKvkNNKLYVKLDLIKSNGKTVAYEKYNSDIRK 93

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1024336636  79 VVNDRGNITMINNVTAFTANIYYKSiIKITITVKVG 114
Cdd:NF041002   94 RVNGKGHQPLLQGVKSVSFSQKNNQ-VTIKVTFENG 128
ComGF pfam15980
Putative Competence protein ComGF; ComGF is a family of putative bacterial competence proteins.
 23-115 7.51e-03

Putative Competence protein ComGF; ComGF is a family of putative bacterial competence proteins.


Pssm-ID: 435051  Cd Length: 99  Bit Score: 33.43  E-value: 7.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1024336636  23 ESRELTTVDFEFFSRDILEDFKGVDrnDIEIRQQRIILHKGEE-MIEYKLINNKIIKVVNDRGNITMINNVTAFtaNIYY 101
Cdd:pfam15980   8 ELQNNNQIEWQLFLIQLENELKESK--LVKVEGNKLFYVKKEGdTITYEKYNNKIRRRVNGGGYQPLLQNVKNV--QFEQ 83

                          90
                  ....*....|....*
gi 1024336636 102 KS-IIKITITVKVGT 115
Cdd:pfam15980  84 ENnLVYITVTFKNGE 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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