|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
2-432 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 869.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 2 GKNVVVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALM 81
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 82 KEMGELEARGIPVRERLLLSEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAVK 161
Cdd:PRK01117 81 KEIDELEARGVDVRERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 162 LKEIIDYHNFQLVNYYKVEAVDYQATLDYVLSIADILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVTS 241
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 242 SNTTAGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQ 321
Cdd:PRK01117 241 SNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAVR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 322 INSLSGFCLTKLDVLDGLKEVKICVGYRMpDGREMDTTPLAAEGWEGIEPIYETLPGWSDTTFGVKEHSKLPQAALDYIK 401
Cdd:PRK01117 321 VNGLTGLALTKLDVLDGLEEIKICVAYEL-DGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIK 399
|
410 420 430
....*....|....*....|....*....|.
gi 1013945943 402 RIEELTGVPVDIISTGPDRSETMILRDPFDA 432
Cdd:PRK01117 400 RIEELTGVPISIISTGPDRDQTIILRDPFAA 430
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
4-427 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 803.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 4 NVVVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALMKE 83
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 84 MGELEARGIPVRERLLLSEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAVKLK 163
Cdd:COG0104 81 IDGLEARGVDVRSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 164 EIIDYHNFQLVNYYKVEAVDYQATLDYVLSIADILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVTSSN 243
Cdd:COG0104 161 ELLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 244 TTAGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQIN 323
Cdd:COG0104 241 TTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRIN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 324 SLSGFCLTKLDVLDGLKEVKICVGYRMpDGREMDTTPLAAEGWEGIEPIYETLPGWSDTTFGVKEHSKLPQAALDYIKRI 403
Cdd:COG0104 321 GLTGLALTKLDVLDGLDEIKVCVAYEL-DGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERI 399
|
410 420
....*....|....*....|....
gi 1013945943 404 EELTGVPVDIISTGPDRSETMILR 427
Cdd:COG0104 400 EELLGVPISIVSVGPDREQTIVRR 423
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
6-424 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 755.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 6 VVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALMKEMG 85
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 86 ELEARGIPVRERLLLSEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAVKLKEI 165
Cdd:pfam00709 81 ELEERGIDVPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 166 IDYHNFQLVNYYKvEAVDYQATLDYVLSIADILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVTSSNTT 245
Cdd:pfam00709 161 LELKNKLLEKLYG-EPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 246 AGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQINSL 325
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 326 SGFCLTKLDVLDGLKEVKICVGYRmPDGREMDTTPLAAEGWEGIEPIYETLPGWSDTTFGVKEHSKLPQAALDYIKRIEE 405
Cdd:pfam00709 320 TGLALTKLDVLDGLDEIKVCVAYE-LDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEE 398
|
410
....*....|....*....
gi 1013945943 406 LTGVPVDIISTGPDRSETM 424
Cdd:pfam00709 399 LLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
4-425 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 741.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 4 NVVVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALMKE 83
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 84 MGELEARGIPVRERLLLSEACPLILPYHVALDNAREKARgakaIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAVKLK 163
Cdd:smart00788 81 IEELEAKGVDVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 164 EIIDYHNFQLVNYYKVEAVDYQATLDYVLSIADILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVTSSN 243
Cdd:smart00788 157 ELLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 244 TTAGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQIN 323
Cdd:smart00788 237 TTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRIN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 324 SLSGFCLTKLDVLDGLKEVKICVGYRmPDGREMDTTPLAAEGWEGIEPIYETLPGWSDTTFGVKEHSKLPQAALDYIKRI 403
Cdd:smart00788 317 GITGLALTKLDVLDGLDEIKVCVAYK-LDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERI 395
|
410 420
....*....|....*....|..
gi 1013945943 404 EELTGVPVDIISTGPDRSETMI 425
Cdd:smart00788 396 EELVGVPVSIISTGPDREQTIV 417
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
6-431 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 692.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 6 VVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALMKEMG 85
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 86 ELEARGIPVRERLLLSEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAVKLKEI 165
Cdd:TIGR00184 81 YLEKRGISVRDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 166 IDYHNFQLVNYYKVEAVDYQATLDYVLSIADILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVTSSNTT 245
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 246 AGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQINSL 325
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 326 SGFCLTKLDVLDGLKEVKICVGYRMpDGREMDTTPLAAEGWEGIEPIYETLPGWSDTTFGVKEHSKLPQAALDYIKRIEE 405
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRM-KGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEE 399
|
410 420
....*....|....*....|....*.
gi 1013945943 406 LTGVPVDIISTGPDRSETMILRDPFD 431
Cdd:TIGR00184 400 LTGVPVTIISTGPEREQTIDLRKELL 425
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
3-425 |
3.71e-180 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 504.73 E-value: 3.71e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 3 KNVVVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALMK 82
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 83 EMGELEARGIPVRERLLLSEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDlfnketfavkl 162
Cdd:cd03108 81 EIEELEKKGIDVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 163 keiidyhnfqlvnyykveavdyqatldyvlsiadiltAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVTSS 242
Cdd:cd03108 150 -------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSS 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 243 NTTAGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQI 322
Cdd:cd03108 193 NTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRI 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 323 NSLSGFCLTKLDVldglkevkicvgyrmpdgremdttplaaegwegiepiyetlpgwsdttfgvkehsklpqAALDYIKR 402
Cdd:cd03108 273 NGLTELALTKLDV-----------------------------------------------------------NAQKYIER 293
|
410 420
....*....|....*....|...
gi 1013945943 403 IEELTGVPVDIISTGPDRSETMI 425
Cdd:cd03108 294 IEELLGVPITYISVGPDREQTII 316
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
6-323 |
7.97e-33 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 125.56 E-value: 7.97e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 6 VVLGTQWGDEGKGKVVDLLTERAQYVVRYQ-GGHNAGHTlVIN--GEKTVLHLIPSGILRDN-VTSIIGNGVVLAPDALM 81
Cdd:NF038379 3 VVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHT-YIDdeGRKFVHRMLPNGIVSPPlKQVLIGPGSEIDLEVLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 82 KEMGELEARGIPVRERLLLSE-ACPLILPYHValdnaREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAV 160
Cdd:NF038379 82 EEIEELEDAGHDVGKRLLIHEqATVIELHKHV-----EEEAGPMTKIGSTKKGIGAARAAKIRRNPSTLGDAEGDFGEGA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 161 KLKEIIDYHnfqlvnyykVEAVDYqatldyvlsiadiltamvvdvsELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVT 240
Cdd:NF038379 157 VRDQPWEIA---------ERVVDN----------------------ALYDFALQAAERIQIEGTQGYSLGLHAGFYPYCT 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 241 SSNTTAGGVATGSGIGPRYVDY--VLGIVKAYSTRVGA-----GPFPTEL-FDETGeylckQGNEFGATTGRRRRTGWLD 312
Cdd:NF038379 206 SRDCTPADFLADAGIPLPNVDAfkVVGTARTYPIRVAGwsgnsYPDQGETtWEELG-----LPEELTTVTKKVRRVGTFS 280
|
330
....*....|.
gi 1013945943 313 AVAVRRAVQIN 323
Cdd:NF038379 281 AEQVREAVQAN 291
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
2-432 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 869.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 2 GKNVVVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALM 81
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 82 KEMGELEARGIPVRERLLLSEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAVK 161
Cdd:PRK01117 81 KEIDELEARGVDVRERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 162 LKEIIDYHNFQLVNYYKVEAVDYQATLDYVLSIADILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVTS 241
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 242 SNTTAGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQ 321
Cdd:PRK01117 241 SNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAVR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 322 INSLSGFCLTKLDVLDGLKEVKICVGYRMpDGREMDTTPLAAEGWEGIEPIYETLPGWSDTTFGVKEHSKLPQAALDYIK 401
Cdd:PRK01117 321 VNGLTGLALTKLDVLDGLEEIKICVAYEL-DGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIK 399
|
410 420 430
....*....|....*....|....*....|.
gi 1013945943 402 RIEELTGVPVDIISTGPDRSETMILRDPFDA 432
Cdd:PRK01117 400 RIEELTGVPISIISTGPDRDQTIILRDPFAA 430
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
4-427 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 803.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 4 NVVVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALMKE 83
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 84 MGELEARGIPVRERLLLSEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAVKLK 163
Cdd:COG0104 81 IDGLEARGVDVRSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 164 EIIDYHNFQLVNYYKVEAVDYQATLDYVLSIADILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVTSSN 243
Cdd:COG0104 161 ELLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 244 TTAGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQIN 323
Cdd:COG0104 241 TTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRIN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 324 SLSGFCLTKLDVLDGLKEVKICVGYRMpDGREMDTTPLAAEGWEGIEPIYETLPGWSDTTFGVKEHSKLPQAALDYIKRI 403
Cdd:COG0104 321 GLTGLALTKLDVLDGLDEIKVCVAYEL-DGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERI 399
|
410 420
....*....|....*....|....
gi 1013945943 404 EELTGVPVDIISTGPDRSETMILR 427
Cdd:COG0104 400 EELLGVPISIVSVGPDREQTIVRR 423
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
6-424 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 755.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 6 VVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALMKEMG 85
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 86 ELEARGIPVRERLLLSEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAVKLKEI 165
Cdd:pfam00709 81 ELEERGIDVPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 166 IDYHNFQLVNYYKvEAVDYQATLDYVLSIADILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVTSSNTT 245
Cdd:pfam00709 161 LELKNKLLEKLYG-EPLDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 246 AGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQINSL 325
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 326 SGFCLTKLDVLDGLKEVKICVGYRmPDGREMDTTPLAAEGWEGIEPIYETLPGWSDTTFGVKEHSKLPQAALDYIKRIEE 405
Cdd:pfam00709 320 TGLALTKLDVLDGLDEIKVCVAYE-LDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEE 398
|
410
....*....|....*....
gi 1013945943 406 LTGVPVDIISTGPDRSETM 424
Cdd:pfam00709 399 LLGVPIKIISVGPDREQTI 417
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
4-425 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 741.99 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 4 NVVVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALMKE 83
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 84 MGELEARGIPVRERLLLSEACPLILPYHVALDNAREKARgakaIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAVKLK 163
Cdd:smart00788 81 IEELEAKGVDVKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 164 EIIDYHNFQLVNYYKVEAVDYQATLDYVLSIADILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVTSSN 243
Cdd:smart00788 157 ELLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 244 TTAGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQIN 323
Cdd:smart00788 237 TTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRIN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 324 SLSGFCLTKLDVLDGLKEVKICVGYRmPDGREMDTTPLAAEGWEGIEPIYETLPGWSDTTFGVKEHSKLPQAALDYIKRI 403
Cdd:smart00788 317 GITGLALTKLDVLDGLDEIKVCVAYK-LDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERI 395
|
410 420
....*....|....*....|..
gi 1013945943 404 EELTGVPVDIISTGPDRSETMI 425
Cdd:smart00788 396 EELVGVPVSIISTGPDREQTIV 417
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
6-431 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 692.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 6 VVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALMKEMG 85
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 86 ELEARGIPVRERLLLSEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAVKLKEI 165
Cdd:TIGR00184 81 YLEKRGISVRDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 166 IDYHNFQLVNYYKVEAVDYQATLDYVLSIADILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVTSSNTT 245
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 246 AGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQINSL 325
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 326 SGFCLTKLDVLDGLKEVKICVGYRMpDGREMDTTPLAAEGWEGIEPIYETLPGWSDTTFGVKEHSKLPQAALDYIKRIEE 405
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRM-KGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEE 399
|
410 420
....*....|....*....|....*.
gi 1013945943 406 LTGVPVDIISTGPDRSETMILRDPFD 431
Cdd:TIGR00184 400 LTGVPVTIISTGPEREQTIDLRKELL 425
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
1-427 |
0e+00 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 555.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 1 MGKNVVVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVIN-GEKTVLHLIPSGILRDNVTSIIGNGVVLAPDA 79
Cdd:PLN02513 1 LSQVSAVLGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNDeGKKFALHLVPSGILNEKTTCVIGNGVVVHLPG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 80 LMKEMGELEARGIPVRERLLLSEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFA 159
Cdd:PLN02513 81 LFEEIDGLESNGVSCEGRLLVSDRAHLLFDFHQEVDGLREAELAGSKIGTTKRGIGPAYSSKATRNGLRVGDLRHMDTFA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 160 VKLKEIIDYHNFQLvNYYKVEAVDYQATLDYVLSIADILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYV 239
Cdd:PLN02513 161 EKLRELLADAAARF-EGFEYDASMVEEEVEAYKKFAERLEPFITDTVHYLNEAIQAGKKILVEGAQATMLDIDFGTYPFV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 240 TSSNTTAGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRA 319
Cdd:PLN02513 240 TSSNPSAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIVALKYS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 320 VQINSLSGFCLTKLDVLDGLKEVKICVGYRMPDGREMDTTPLAAEGWEGIEPIYETLPGWSDTTFGVKEHSKLPQAALDY 399
Cdd:PLN02513 320 CQINGFTSLNLTKLDVLSGLPEIKIGVAYKTPDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPAAAQAY 399
|
410 420
....*....|....*....|....*...
gi 1013945943 400 IKRIEELTGVPVDIISTGPDRSETMILR 427
Cdd:PLN02513 400 VERIEELVGVPVHYIGVGPGRDALIVKP 427
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
2-428 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 511.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 2 GKNVVVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALM 81
Cdd:PTZ00350 12 SKVVVILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSLL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 82 KEMGELEARGIPVRERLLLSEACPLILPYHVALDNARE--KARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFA 159
Cdd:PTZ00350 92 EEIEQLTKKGINLLGRLYISDRAHLVFDLHQAIDGIQEseKGKGGTQIGTTKRGIGPCYSTKASRTGLRVGDLLNFETFE 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 160 VKLKEIIDYHNFQlvnyYKVEAVDYQATLDYVLSIADILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYV 239
Cdd:PTZ00350 172 KKYRKLVEKLQEQ----YNIEEYDAEEELERYKGYAEKLKDMIVDTVYFMNKAIKEGKRVLVEGANATMLDIDFGTYPYV 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 240 TSSNTTAGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRA 319
Cdd:PTZ00350 248 TSSNTTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRYV 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 320 VQINSLSGFCLTKLDVLDGLKEVKICVGYRMP-DGREMDTTPLAAEGWEGIEPIYETLPGWSDTTFGVKEHSKLPQAALD 398
Cdd:PTZ00350 328 QMINGFDSINLTKLDVLSGLKEIKICVNYKNKgTGLEIGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQK 407
|
410 420 430
....*....|....*....|....*....|
gi 1013945943 399 YIKRIEELTGVPVDIISTGPDRsETMILRD 428
Cdd:PTZ00350 408 YVLFIEELLGVPIVWIGVGPNR-ENMIVKK 436
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
3-425 |
3.71e-180 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 504.73 E-value: 3.71e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 3 KNVVVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALMK 82
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 83 EMGELEARGIPVRERLLLSEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDlfnketfavkl 162
Cdd:cd03108 81 EIEELEKKGIDVKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 163 keiidyhnfqlvnyykveavdyqatldyvlsiadiltAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVTSS 242
Cdd:cd03108 150 -------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSS 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 243 NTTAGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQI 322
Cdd:cd03108 193 NTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRI 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 323 NSLSGFCLTKLDVldglkevkicvgyrmpdgremdttplaaegwegiepiyetlpgwsdttfgvkehsklpqAALDYIKR 402
Cdd:cd03108 273 NGLTELALTKLDV-----------------------------------------------------------NAQKYIER 293
|
410 420
....*....|....*....|...
gi 1013945943 403 IEELTGVPVDIISTGPDRSETMI 425
Cdd:cd03108 294 IEELLGVPITYISVGPDREQTII 316
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
1-426 |
5.17e-154 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 442.85 E-value: 5.17e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 1 MGKNVVVlGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDAL 80
Cdd:PRK13787 1 MPASLVV-GTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 81 MKEMGELEARGIPVRERLLLSEACPLILPYHVALDNAREKARGA-KAIGTTGRGIGPAYEDKVARRGLRVGDLFNKeTFA 159
Cdd:PRK13787 80 IEECDRLQKEGFPVKDKLLLSDACHLLFPYHSQIDSARETTSSQeHKIGTTKKGIGICYADKMMRTGLRVGDLLDK-SYK 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 160 VKLKEIIDYHNFQLVNYYKVEAVDYQATLDYVLSIADILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYV 239
Cdd:PRK13787 159 RRLKHLVDEKNRELDKLYGMPPVSYNDINDGLKFFLSKVGKNIINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYV 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 240 TSSNTTAGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRA 319
Cdd:PRK13787 239 TSSNPTTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDVEMLKHS 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 320 VQINSLSGFCLTKLDVLDGLKEVKICVGYRMpDGREMDTTPlaAEGWEGIEPIYETLPGWSDTTFGVKEHSKLPQAALDY 399
Cdd:PRK13787 319 VRINGITSIALTKIDILSDYDTIPVAVGYKL-NGKTLDCFP--SQGLEKVEPLYEEFPGWKDDISGINEFQKLPEKCKNY 395
|
410 420
....*....|....*....|....*..
gi 1013945943 400 IKRIEELTGVPVDIISTGPDRSETMIL 426
Cdd:PRK13787 396 ISALEKWIGVKINLVSTGPDRKDTIIG 422
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
3-424 |
4.34e-138 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 401.40 E-value: 4.34e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 3 KNVVVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALMK 82
Cdd:PRK13783 1 MKRVIVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTVNYGDFKVVHHLLPSADFKKNVGAAIGNGVVLDLEVLVE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 83 EMGELEARGIPVRERLLLSEACPLILPYHVALDNAREKARGaKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAVKL 162
Cdd:PRK13783 81 ELEELKEKFPDYSGRIFISELAHVVLPVHKELDEIIESVRK-NAIGTTKRGIGPAYADKVMRVGVRLADLFDEEKLREFL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 163 KEIIDYHNfqlvNYYKVEaVDYQATLDYVLSIADILTAMVVDVSELLDGARKRGdlIMFEGAQGTLLDIDHGTYPYVTSS 242
Cdd:PRK13783 160 EKILSLYK----KLYGIE-FDVEKMMEDLLTFYEKIKDLVVSPVEIKRILEEKS--VLFEGTQGVLLDLDVGTYPYVTSS 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 243 NTTAGGVATGSGIgPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQI 322
Cdd:PRK13783 233 NCSTTGVSAGMGF-PVKVDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYAIEV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 323 NSLSGFCLTKLDVLDGLKEVKICVGYRmpDGREMDTTPLAAEGWEGIEPIYETLPGWSDTtfgvkeHSKlpqAALDYIKR 402
Cdd:PRK13783 312 SGVDSLVMTKADVLNGFEKIKVCVRYE--IGGKEVRDPSSLRDLEKAEPVYEEFDGWKSL------EDK---NFLKFVDF 380
|
410 420
....*....|....*....|..
gi 1013945943 403 IEELTGVPVDIISTGPDRSETM 424
Cdd:PRK13783 381 IERETGRKIAYISTGPKIEEIV 402
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
6-423 |
9.02e-136 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 396.09 E-value: 9.02e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 6 VVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTsIIGNGVVLAPDALMKEMG 85
Cdd:PRK13786 4 IITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKVGDEVYKLHLIPSGFLLDARV-LIGPGVVLNPEVLAEEID 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 86 ELEARGIPVR-ERLLLSEACPLILPYHVALDNAREKARGAKaIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAVKLKE 164
Cdd:PRK13786 83 MLEKHGVKVDaEKLGIDAKTSIIMPYHIELDGLRESARTEK-IGTTKRGIGFAYIDKIARDEVRMSDLVDKERLMRRLEE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 165 IIDyhnfQLVNYYKV-----EAVDYQATLDYVLSIADILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYV 239
Cdd:PRK13786 162 LAP----QKEKEIKElggdpSIVRDEALIDKYLELGRQLAPYITDVSYEINKALDEGKSVLAEGAQGTHLDVIHGTQKFV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 240 TSSNTTAGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRA 319
Cdd:PRK13786 238 TSSSTIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPLLKKA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 320 VQINSLSGFCLTKLDVLDGLKEVKICVGYRMpDGREMDTTPLAAEGWEGIEPIYETLPGWSDTTFGVKEHSKLPQAALDY 399
Cdd:PRK13786 318 IYLNGYTEIALTKLDVLTGLDPIKICVGYEL-DGEILDYPPELTSDLARCVPVYEELEGWSTDLTEVKAYEDLPENARNY 396
|
410 420
....*....|....*....|....
gi 1013945943 400 IKRIEELTGVPVDIISTGPDRSET 423
Cdd:PRK13786 397 VERLEELMGVPIKYISVGPGREQT 420
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
5-423 |
1.33e-132 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 387.62 E-value: 1.33e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 5 VVVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALMKEM 84
Cdd:PRK13788 4 IAIIGAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVAKGKTFKLNLLPSGVLHPHATSVLGDGMVIDPFRFAEER 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 85 GELEARGIPvrERLLLSEACPLILPYHVALDNarekarGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAVKLKE 164
Cdd:PRK13788 84 ENLRAGGLN--PKLLISERAHLVLPHHKYVDG------RKNFVGTTGRGIGPAYSDRARRVGIRFGDLLDEAVLRERVER 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 165 IIDY--HNFQLVNYYKVEAvdyqaTLDYVLSIADILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVTSS 242
Cdd:PRK13788 156 LLEAkpNSTREAGWDTVEK-----ALADLAPMREILLPFIADTGSLLREAIREGKRVLFEGAQATLLDLNYGTYPYVTSS 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 243 NTTAGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQG----NEFGATTGRRRRTGWLDAVAVRR 318
Cdd:PRK13788 231 HPTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLDLVLLKY 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 319 AVQINSLSGFCLTKLDVLDGLKEVKICVGYRmPDGRemdttplaaegwegiePIYETLPGWSDTTfGVKEHSKLPQAALD 398
Cdd:PRK13788 311 ACEVNGFDGLVLTKLDVLSGLEKVKVCVEYD-DDGQ----------------PVYKELPGWGDLD-GVKSREALPKEAQA 372
|
410 420
....*....|....*....|....*
gi 1013945943 399 YIKRIEELTGVPVDIISTGPDRSET 423
Cdd:PRK13788 373 YLELIEETTGVPVVMFSTSPRREDT 397
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
5-430 |
6.24e-123 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 364.47 E-value: 6.24e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 5 VVVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVtSIIGNGVVLAPDALMKEM 84
Cdd:PRK13785 3 VTIVGSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAVRGKI-GVLGNGCVVNPETLFDEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 85 GELEARGIPVRERLllSEACPLILPYHVALDNARE--KARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAVKL 162
Cdd:PRK13785 82 DALRERGLDPDVRV--AERAHVILPYHRVLDGIEEeaKSDSDLEVGTTGRGIGPTYEDKAGRRGVRVGDLLDPDVLRDRL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 163 KEIIDYHNFQLVNYYKV------EAVDYQATLDYVLSIADILTA--MVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHG 234
Cdd:PRK13785 160 EYVVPQKRALAEDVYGLdasetpEAFDVDALFEEYREYGERLAEedMTVNAGDFLAERIDDGDNVMLEGAQGTSIDIDHG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 235 TYPYVTSSNTTAGGVATGSGIGPRYVDY--VLGIVKAYSTRVGAGPFPTEL---------------FDETGEYLCKQGNE 297
Cdd:PRK13785 240 NYPYVTSSNPTAGGAATGTGLGPTVVGQgeVVGIVKAYLSRVGSGPLPTELggvegdtpdeggrpdEEELATYIREEGGE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 298 FGATTGRRRRTGWLDAVAVRRAVQINSLSGFCLTKLDVLDGLKEVKICVGYRMpDGREMDTTPLAAEGWEGIEPIYETLP 377
Cdd:PRK13785 320 YGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYEL-DGEELLTMPATTERWARCEPNFRSFD 398
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 1013945943 378 GWSDTTFGV---KEHSKLPQAALDYIKRIEELTGVPVDIISTGPDRSETMILRDPF 430
Cdd:PRK13785 399 GWPEVDWAAvaeEGYDALPENARTYLEYVSDELDTPIYAVGVGPGREETVVLENPF 454
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
4-430 |
6.38e-119 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 353.56 E-value: 6.38e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 4 NVVVLGTQWGDEGKGKVVDLLTERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALMKE 83
Cdd:PRK13784 3 NIVIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALDEE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 84 MGELEARGIPVR-ERLLLSEACPLILPYHVALDNAREKARGAKaIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAVKL 162
Cdd:PRK13784 83 ITRLQAKGIAISaENLFVSESCTIITSYHKLLDAVRESNTSEK-IGTTGKGIGPAYEDKVSRKGIKFKHLFDKDLLRSRL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 163 KEIIDYHNFQLVNYYKVEAVDYQATLDYVLSIADILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVTSS 242
Cdd:PRK13784 162 AISLAEKETLFRDLYKVEYPTLEQEFDKLFALGQKLKQYAADTFSIIDQAIAAGKNVVYEGAQGVLLDVDYGTYPFVTSS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 243 NTTAGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQGNEFGATTGRRRRTGWLDAVAVRRAVQI 322
Cdd:PRK13784 242 NTSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLPLLKYSAKC 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 323 NSLSGFCLTKLDVLDGLKEVKICVGYRMpDGREMDTTPLAAEGWEgIEPIYETLPGWSDTTFGVKEHskLPQAALDYIKR 402
Cdd:PRK13784 322 SNLTSIALTKVDVLSDMDTLKVCIGYKY-EGKEIYCAYPGIDLYK-VEPILVEMEPFSIDETVTKDN--MPAALKTYLKT 397
|
410 420
....*....|....*....|....*...
gi 1013945943 403 IEELTGVPVDIISTGPDRSETMILRDPF 430
Cdd:PRK13784 398 IENHVGIPISSLAYGPSREQILFFEDYF 425
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
6-427 |
7.66e-92 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 280.61 E-value: 7.66e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 6 VVLGTQWGDEGKGKVVDLL--TERAQYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALMKE 83
Cdd:PRK04293 5 IVVGGFFGDEGKGKIIAYLalKDKPSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLAIGAGVLVDPEVLLKE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 84 MGELEargipVRERLLLSEACPLILPYHVALDnaREKARGAKAIGTTGRGIGPAYEDKVARRGlrvgdlfnketfavKLk 163
Cdd:PRK04293 85 VEELN-----VGGRVFVDYRCGIIEEKHVEED--RSDEHLSKKIGSTGTGCGPANADRVLRRL--------------KL- 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 164 eiidyhnfqlvnyykveAVDYqatldyvlsiaDILTAMVVDVSELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVTSSN 243
Cdd:PRK04293 143 -----------------AKDV-----------EELEKYLTDVPEEVNEALDRGENVLIEGTQGFGLSLYYGTYPYVTSKD 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 244 TTAGGVATGSGIGPRYVDYVLGIVKAYSTRVGAGPFPTELFDETGEYLCKQgnEFGATTGRRRRTGWLDAVAVRRAVQIN 323
Cdd:PRK04293 195 TTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLEEAEKLGLV--EYGTVTGRRRRVGPFDFELARRAARIN 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 324 SLSGFCLTKLDVLDglKEVkicvgyrmpdgremdttplaaegwegiepiyetlpgwsdttFGVKEHSKLPQAALDYIKRI 403
Cdd:PRK04293 273 GATQIAITKLDKLD--KEA-----------------------------------------YGVTEYDKLPPEAKKFIEEI 309
|
410 420
....*....|....*....|....
gi 1013945943 404 EELTGVPVDIISTGPDRSETMILR 427
Cdd:PRK04293 310 EEELGVPVTLISTGPELEDTIDLR 333
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
6-323 |
7.97e-33 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 125.56 E-value: 7.97e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 6 VVLGTQWGDEGKGKVVDLLTERAQYVVRYQ-GGHNAGHTlVIN--GEKTVLHLIPSGILRDN-VTSIIGNGVVLAPDALM 81
Cdd:NF038379 3 VVVDGQFGSTGKGLIAGYLAERAAPDVVVRaAGPNAGHT-YIDdeGRKFVHRMLPNGIVSPPlKQVLIGPGSEIDLEVLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 82 KEMGELEARGIPVRERLLLSE-ACPLILPYHValdnaREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFNKETFAV 160
Cdd:NF038379 82 EEIEELEDAGHDVGKRLLIHEqATVIELHKHV-----EEEAGPMTKIGSTKKGIGAARAAKIRRNPSTLGDAEGDFGEGA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 161 KLKEIIDYHnfqlvnyykVEAVDYqatldyvlsiadiltamvvdvsELLDGARKRGDLIMFEGAQGTLLDIDHGTYPYVT 240
Cdd:NF038379 157 VRDQPWEIA---------ERVVDN----------------------ALYDFALQAAERIQIEGTQGYSLGLHAGFYPYCT 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 241 SSNTTAGGVATGSGIGPRYVDY--VLGIVKAYSTRVGA-----GPFPTEL-FDETGeylckQGNEFGATTGRRRRTGWLD 312
Cdd:NF038379 206 SRDCTPADFLADAGIPLPNVDAfkVVGTARTYPIRVAGwsgnsYPDQGETtWEELG-----LPEELTTVTKKVRRVGTFS 280
|
330
....*....|.
gi 1013945943 313 AVAVRRAVQIN 323
Cdd:NF038379 281 AEQVREAVQAN 291
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
5-427 |
3.79e-29 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 120.16 E-value: 3.79e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 5 VVVLGTQWGDEGKGKVVDLLTER--AQYVVRYQGGHNAGHTLVIN-GEKTVLHLIPSGILRDNVTSIIGNGVVLAPDALM 81
Cdd:PTZ00351 172 IMVAGAFFGDEGKGKTVDAVAHHplCTCIARVNSGENAGHTVYDKaGRKFVFNLAPSGLLLPGKRNYIGPECVMDPVSFM 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 82 -KEMGELEARGIPVRERLLLSEACpLILPYHVALDnarekARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFN-KETFA 159
Cdd:PTZ00351 252 eKEIIQLIDAGIDYRDRLFIGNVC-IVTPYHKLLD-----LLGSAANSSTLKGMAPVHGSKVMKRGIRLDHIFNdDETLR 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 160 VKLKEIIDYHnFQLVNYYKVEAVDY-----QATLDYVLSIADILTAMV--------------------------VDVSEL 208
Cdd:PTZ00351 326 KRLEKDMDTY-LGLLKVKNLSDADVvrlcrEENSDGVVRVPDYVIAFAqakdkveflvklyrdrvrhnpdfparCDVTYE 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 209 LDGARKRGDLIMFEGAQGTLLDIDHGTY-PYVTSSNTTAGGVATGSGIG-PRYVDYVLGIVKAY-STRVGAG-------- 277
Cdd:PTZ00351 405 LHAAVLRGEKVLLEGPQSYWLSNARTKFwESTTSADTTAAGLLAASQLNfQKFKSVVLNVHKAPgSSRVGIGacpssfvp 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 278 -----------------------------------PF------------PTELFDETGEY---------LCKQGNEFGAT 301
Cdd:PTZ00351 485 qdyfsaqniktlrdlpsatcanfeavqrtlfrdgfPHsndkarhngimaPVEYSDETGDYnigvamaiaSAQHHGECGAV 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1013945943 302 TGRRRRTGWLDAVAVRravQINSLSGFCLT--KLDVLDGLKEVKICVGYRM--PDGREMDTT--------------PLAA 363
Cdd:PTZ00351 565 TKKPRVCGFFDCVLQH---EVNSIQGPYLTisALDRGDEYDKVGVTIAYVYynPEGKQVDVNghvykngdiiragdPVPS 641
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1013945943 364 E-GWEGIEPIYETLPGWSDTTFGV---KEHSKLPQAALDYIKRIEELTGVPVDIISTGPDRSETMILR 427
Cdd:PTZ00351 642 EpALYHCHPIVKLIDGWRDNPIAAakrRRNAPLPRGVCELLSTIEYFTNCKILSIGNGPNGDDIIYLR 709
|
|
| |
