|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
1-345 |
0e+00 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 699.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 1 MNDEMKGKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRP-GKSRADGGRRPARDDKQSQPRDRKWEDSPWRTVSRAPGDE 79
Cdd:PRK10864 1 MNDELKGKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRPsGKSRADGGRRPARDDRNSQSRDRKWEDSPWRTVSRAPGDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 80 TPEKADHGGISGKSFIDPEVLRRQRAEETRVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDE 159
Cdd:PRK10864 81 TPEKADHGGISGKSFIDPEVLRRQRAEETRVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 160 AELTKASGTEHHGGVCFLIKKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSCAHFGVKGVVVQDAALLESGAA 239
Cdd:PRK10864 161 AELTKASGTEHHGGVCFLIKKRNGTDVQQWLAQAGAQDCVLALEDVGNPHNLGGIMRSCAHFGVKGVVVQDAALLESGAA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 240 IRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTSSEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDG 319
Cdd:PRK10864 241 IRTAEGGAEHVQPITGDSFVDVLDDFRQAGYTIVTTSSHKGTPLFKASLPAKMVLVLGQEYDGLSDAARQQGDLSVSIDG 320
|
330 340
....*....|....*....|....*.
gi 1000560672 320 TGNVAGLNISVATGVLLGEWWRQNKA 345
Cdd:PRK10864 321 TGNVESLNVSVATGVLLAEWWRQNKA 346
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
101-345 |
9.32e-65 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 205.82 E-value: 9.32e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 101 RRQRAEETR--VYGENACQALFQSRpEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEAELTKASGTEHHGGVCFLI 178
Cdd:COG0566 18 KKYREEEGLflAEGRHAVEEALKAG-REIEELLVTEGALDRLAELLALAKAAGIPVYEVSREVLDKLSGTETHQGVLAVV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 179 KKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSCAHFGVKGVVV-QDAALLESGAAIRTAEGGAEHVQPITGDN 257
Cdd:COG0566 97 RPPEYADLEDLLAEAGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILpKRRADPYNPKVVRASAGALFHVPVARVTN 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 258 IVNVLDDFRQAGYTVVTTSSEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLLG 337
Cdd:COG0566 177 LADALEELKEAGFWVVGTDLDGEASLYEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAILLY 256
|
....*...
gi 1000560672 338 EWWRQNKA 345
Cdd:COG0566 257 EAARQRRA 264
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
198-339 |
6.33e-47 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 155.66 E-value: 6.33e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 198 CVLALENESNPHNLGGMMRSCAHFGVKGVVV-QDAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTS 276
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGVILsKGTVDPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEAGYKVVAAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1000560672 277 SEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLLGEW 339
Cdd:cd18095 81 LDGGSSLYDLDLPKPVALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYEL 143
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
199-336 |
2.41e-39 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 136.12 E-value: 2.41e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 199 VLALENESNPHNLGGMMRSCAHFGVKGVVV--QDAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTS 276
Cdd:pfam00588 3 VVVLDNIQDPGNLGAIIRTAAAFGADGLILvePRSADPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVATS 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 277 SEqGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLL 336
Cdd:pfam00588 83 LG-GKSLYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIAL 141
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
109-342 |
1.17e-25 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 102.81 E-value: 1.17e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 109 RVYGENACQALFQSRPEAivrawFIQSVT--PRFKEALRWMAANRKAYHVVDEAELTKASGTEHHGGVCFLIKKRNGTTV 186
Cdd:TIGR00186 3 YLYGKNAVLEALLNQQRV-----FILKGLesKRLKKLIQLAKKQGINIQLVDRQKLDQLTKGGNHQGIAAKVKPILYKDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 187 QQWVSQAGAQDC--VLALENESNPHNLGGMMRSCAHFGVKGVVV--QDAALLESGaAIRTAEGGAEHVQPITGDNIVNVL 262
Cdd:TIGR00186 78 NDLYKTAKSKKQpfLLILDEITDPHNLGAILRTAEAFGVDGVILpkRRSAPLNST-VVKTSSGAVEYVPLARVTNLSRTI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 263 DDFRQAGYTVVTTSSEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLLGEWWRQ 342
Cdd:TIGR00186 157 TKLKESGFWTVGTDLDAQDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKRQ 236
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
110-180 |
7.49e-09 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 51.77 E-value: 7.49e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1000560672 110 VYGENACQALFQSrPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEAELTKASGTEHHGGVCFLIKK 180
Cdd:smart00967 1 IEGRHAVEEALKS-GRRIKELYLTEGRAERLKELLKLAKERGIKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
1-345 |
0e+00 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 699.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 1 MNDEMKGKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRP-GKSRADGGRRPARDDKQSQPRDRKWEDSPWRTVSRAPGDE 79
Cdd:PRK10864 1 MNDELKGKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRPsGKSRADGGRRPARDDRNSQSRDRKWEDSPWRTVSRAPGDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 80 TPEKADHGGISGKSFIDPEVLRRQRAEETRVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDE 159
Cdd:PRK10864 81 TPEKADHGGISGKSFIDPEVLRRQRAEETRVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 160 AELTKASGTEHHGGVCFLIKKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSCAHFGVKGVVVQDAALLESGAA 239
Cdd:PRK10864 161 AELTKASGTEHHGGVCFLIKKRNGTDVQQWLAQAGAQDCVLALEDVGNPHNLGGIMRSCAHFGVKGVVVQDAALLESGAA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 240 IRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTSSEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDG 319
Cdd:PRK10864 241 IRTAEGGAEHVQPITGDSFVDVLDDFRQAGYTIVTTSSHKGTPLFKASLPAKMVLVLGQEYDGLSDAARQQGDLSVSIDG 320
|
330 340
....*....|....*....|....*.
gi 1000560672 320 TGNVAGLNISVATGVLLGEWWRQNKA 345
Cdd:PRK10864 321 TGNVESLNVSVATGVLLAEWWRQNKA 346
|
|
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
101-345 |
9.32e-65 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 205.82 E-value: 9.32e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 101 RRQRAEETR--VYGENACQALFQSRpEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEAELTKASGTEHHGGVCFLI 178
Cdd:COG0566 18 KKYREEEGLflAEGRHAVEEALKAG-REIEELLVTEGALDRLAELLALAKAAGIPVYEVSREVLDKLSGTETHQGVLAVV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 179 KKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSCAHFGVKGVVV-QDAALLESGAAIRTAEGGAEHVQPITGDN 257
Cdd:COG0566 97 RPPEYADLEDLLAEAGEPPLLLVLDGVQDPGNLGAILRSAAAFGVDGVILpKRRADPYNPKVVRASAGALFHVPVARVTN 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 258 IVNVLDDFRQAGYTVVTTSSEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLLG 337
Cdd:COG0566 177 LADALEELKEAGFWVVGTDLDGEASLYEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAILLY 256
|
....*...
gi 1000560672 338 EWWRQNKA 345
Cdd:COG0566 257 EAARQRRA 264
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
198-339 |
6.33e-47 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 155.66 E-value: 6.33e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 198 CVLALENESNPHNLGGMMRSCAHFGVKGVVV-QDAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTS 276
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGVILsKGTVDPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEAGYKVVAAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1000560672 277 SEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLLGEW 339
Cdd:cd18095 81 LDGGSSLYDLDLPKPVALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYEL 143
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
199-336 |
2.41e-39 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 136.12 E-value: 2.41e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 199 VLALENESNPHNLGGMMRSCAHFGVKGVVV--QDAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTS 276
Cdd:pfam00588 3 VVVLDNIQDPGNLGAIIRTAAAFGADGLILvePRSADPYNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVATS 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 277 SEqGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLL 336
Cdd:pfam00588 83 LG-GKSLYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIAL 141
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
199-339 |
4.21e-32 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 117.10 E-value: 4.21e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 199 VLALENESNPHNLGGMMRSCAHFGVKGVVVQ--DAALLeSGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTS 276
Cdd:cd18103 2 LLILDGITDPHNLGAIIRSAEAFGVDGVIIPkrRSAPL-TPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1000560672 277 SEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLLGEW 339
Cdd:cd18103 81 GEAEKSLYDVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
109-342 |
1.17e-25 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 102.81 E-value: 1.17e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 109 RVYGENACQALFQSRPEAivrawFIQSVT--PRFKEALRWMAANRKAYHVVDEAELTKASGTEHHGGVCFLIKKRNGTTV 186
Cdd:TIGR00186 3 YLYGKNAVLEALLNQQRV-----FILKGLesKRLKKLIQLAKKQGINIQLVDRQKLDQLTKGGNHQGIAAKVKPILYKDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 187 QQWVSQAGAQDC--VLALENESNPHNLGGMMRSCAHFGVKGVVV--QDAALLESGaAIRTAEGGAEHVQPITGDNIVNVL 262
Cdd:TIGR00186 78 NDLYKTAKSKKQpfLLILDEITDPHNLGAILRTAEAFGVDGVILpkRRSAPLNST-VVKTSSGAVEYVPLARVTNLSRTI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 263 DDFRQAGYTVVTTSSEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLLGEWWRQ 342
Cdd:TIGR00186 157 TKLKESGFWTVGTDLDAQDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKRQ 236
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
110-342 |
3.65e-22 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 93.49 E-value: 3.65e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 110 VYGENACQALFQSRPEAIVRAWFIQS-----VTPRFKEALRW----MAANRKAyhvVDEaeltKASGTEHHGGVCFLI-- 178
Cdd:PRK11181 5 IYGIHAVQALLERAPERFIEVFVLKGredkrLLPLINELEAQgiviQLANRQT---LDE----KAEGAVHQGIIARVKpg 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 179 KKRNGTTVQQWVSQAgAQDCVLALENESNPHNLGGMMRSCAHFGVKGVVV-QDAALLESGAAIRTAEGGAEHVQPITGDN 257
Cdd:PRK11181 78 RQLQENDLPDLLASL-EQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVpKDRSAQLNATAKKVACGAAETVPLIRVTN 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 258 IVNVLDDFRQAGYTVVTTSSEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLLG 337
Cdd:PRK11181 157 LARTMRMLQEKNIWIVGTAGEADHTLYQSKLTGPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLF 236
|
....*
gi 1000560672 338 EWWRQ 342
Cdd:PRK11181 237 EAVRQ 241
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
199-339 |
1.10e-21 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 89.59 E-value: 1.10e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 199 VLALENESNPHNLGGMMRSCAHFGVKGV-VVQDAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVV-TTS 276
Cdd:cd18082 1 HLVLDNIRSPGNIGSIFRTADAFGVEKIyLVGPTADIFDPKAKRTSRGTHFSVPYERVDNFEEYLKSLKEEGYPLIgLEL 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1000560672 277 SEQGKPL--FKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLLGEW 339
Cdd:cd18082 81 TDGSIPLseFKFKKPKKIALIFGNERSGLSPELLALCDYTVHIPMSGKNSSLNVSVATGIALYEF 145
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
199-336 |
3.80e-19 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 82.90 E-value: 3.80e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 199 VLALENESNPHNLGGMMRSCAHFGVkgvvvQDAALLESGAAI----RTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVT 274
Cdd:cd18092 18 TVVLENVHDPHNASAVLRTCDAFGV-----QDVHVIEPKNKFkknrGVAMGADKWLDVHRHDSTEECLAALKEQGYRIVA 92
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1000560672 275 TS-SEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLL 336
Cdd:cd18092 93 TSlSPDAVPLDELDYTRPTALVFGNEKDGVSEEALAAADERVYIPMYGFVESLNVSVAAAIIL 155
|
|
| SpoU-like_TRM3-like |
cd18091 |
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O) ... |
207-339 |
1.12e-18 |
|
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O)-methyltransferase TRM3 catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs. TRM3 is similar to C-terminal domain of TAR (HIV-1) RNA binding protein 1 (TARBP1), a protein binding to TAR, which functions as a RNA regulatory signal by forming a stable stem-loop structure to which transactivator protein Tat binds. The role of TARBP1 is believed to be to disengage RNA polymerase II from TAR during transcriptional elongation. TRM3 and the C-terminal methyltransferase domain of TARBP1 are members of the SPOUT methyltransferase superfamily.
Pssm-ID: 349964 Cd Length: 145 Bit Score: 81.42 E-value: 1.12e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 207 NPHNLGGMMRSCAHFGVKGVVVQDAALLESGAAIRTAEGGAEHvQPITG---DNIVNVLDDFRQAGYTVV----TTSSeq 279
Cdd:cd18091 10 KPPNLGGLCRTCEIFGVSKLVLPNLAVVEDKQFKALSVSAEKW-LPIEEvkpEDLLPYLKEKKQEGYTIVgleqTANS-- 86
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 280 gKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLLGEW 339
Cdd:cd18091 87 -VSLHDFQFPKKTVLVLGNEKEGIPAELLSLLDVCVEIPQLGVIRSLNVHVSGAIAIYEY 145
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
199-339 |
2.58e-18 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 80.28 E-value: 2.58e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 199 VLALENESNPHNLGGMMRSCAHFGVKGVVV-QDAALLESGAAIRTAEGGAEHVQPITgDNIVNVLDDFRQAgYTVVTTSS 277
Cdd:cd18109 2 TLALDGIQDPGNLGTIIRTADWFGIRQIICsPDTVDPYNPKVVQASMGSIFRVQIHY-TDLPALLAELKKA-FPVYGADL 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1000560672 278 EqGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVA-GLNISVATGVLLGEW 339
Cdd:cd18109 80 D-GENLYEFTLPEKGILVMGNEGHGISPEVLKLLTHRLTIPRYGKGAeSLNVAVATAILLSEF 141
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
199-336 |
8.01e-17 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 76.40 E-value: 8.01e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 199 VLALENESNPHNLGGMMRSCAHFGVKGVVVQD---AALleSGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTT 275
Cdd:cd18105 2 WLLLDEITDPQNLGAILRSAYFLGVDGVVVSSknsAPL--SPVVSKASAGALELMPIYSVDNLASFLKSSKENGWKVVGT 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1000560672 276 SSEQGKPLFKTSLPA----------KMVLVLGQEYEGLPDAARDPNDLRVKIDG-----TGNVAGLNISVATGVLL 336
Cdd:cd18105 80 SAPPSASSDKKTIPAnelselllekPTILVLGNEGRGLRTNIKNLCDYLVSIPGgrsaeNPGVDSLNVSVAAGILL 155
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
199-338 |
7.85e-14 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 68.18 E-value: 7.85e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 199 VLALENESNPHNLGGMMRSCAHFGVKGVVVQ-DAALLESGAAIRTAEGGAEHvQPITGDNIVNVLDDFRQA------GYT 271
Cdd:cd18107 2 VVLFDRPTSPGNLGTIIRSADALGAHGLVVTgHAADVYDPKTIRASTGSLFS-LPIVRVPSNRELEDWVEArkargtPLQ 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1000560672 272 VVTTSSEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLLGE 338
Cdd:cd18107 81 LVGTDEHGDHQIADHDFTRPTLLLIGNETAGLSAAWRELCDETVSIPMAGSASSLNAACAASIFLYE 147
|
|
| SpoU-like |
cd18096 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
198-339 |
1.50e-13 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349969 Cd Length: 140 Bit Score: 66.86 E-value: 1.50e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 198 CVLALENESNPHNLGGMMRSCAHFGVKGVVVQDAALLesgaAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTT-S 276
Cdd:cd18096 1 LYLVLHNVAKRHNIGTIVRSANAFGVKEVHLVGRRKF----NPFGAMGTDRHVKFRHFDTLAEAKEYLKERGIRLVGVeI 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1000560672 277 SEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGN-VAGLNISVATGVLLGEW 339
Cdd:cd18096 77 VPGAEPIETHPFPGDTAFVLGNEGTGLSDEQLAICDGFVYIPQYGSgTASLNVSVAASIVLHHF 140
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
198-339 |
2.93e-13 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 66.43 E-value: 2.93e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 198 CVLALENESNPHNLGGMMRSCAHFGVKGVVV-QDAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVV--- 273
Cdd:cd18097 1 LVVVLDNLRSAHNVGSIFRTADAAGVEKIYLcGYTPTPPHPKVAKTALGAEESVPWEHFEDTLEAVRALKARGYTIIale 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1000560672 274 TTssEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLLGEW 339
Cdd:cd18097 81 TT--ENSVPLHEARLPRPLALVLGNEVRGVSPEVLALCDAVVEIPMFGRKNSLNVAVAAAVALYEL 144
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
110-180 |
9.20e-13 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 62.64 E-value: 9.20e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1000560672 110 VYGENACQALFQSRPEaIVRAWFIQSV-TPRFKEALRWMAANRKAYHVVDEAELTKASGTEHHGGVCFLIKK 180
Cdd:pfam08032 2 IYGRHAVLEALKSGPE-IKKLYLTEGRrDPRLKELLKLAKERGIKVEEVDRKKLDKLSGTANHQGVVAEVKP 72
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
208-343 |
1.26e-09 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 55.92 E-value: 1.26e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 208 PHNLGGMMRSCAHFGVK-------GVVVQDAALLESGAairtaeGGAEHVQPITGDNivnvLDDFRQA--GYTVVTTSSE 278
Cdd:cd18094 10 PQNTGNIARTCAATGARlhlieplGFSLDDKRLKRAGL------DYWDHVDLTVHDS----WEAFLEAlpPGRLFLFTTK 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1000560672 279 QGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPN-DLRVKIDGTGNVAGLNISVATGVLLGEWWRQN 343
Cdd:cd18094 80 GTKPYTDFDFKPGDYLVFGRESTGLPEEILDAFpDRRLRIPMRPKVRSLNLSNSVAIVLYEALRQL 145
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
110-180 |
7.49e-09 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 51.77 E-value: 7.49e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1000560672 110 VYGENACQALFQSrPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEAELTKASGTEHHGGVCFLIKK 180
Cdd:smart00967 1 IEGRHAVEEALKS-GRRIKELYLTEGRAERLKELLKLAKERGIKVIEVSKKELDKLSGTANHQGVVAVVKP 70
|
|
| TrmL |
COG0219 |
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ... |
208-343 |
3.86e-07 |
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ribosomal structure and biogenesis]; tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439989 Cd Length: 153 Bit Score: 48.88 E-value: 3.86e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 208 PHNLGGMMRSCAHFGVK-------GVVVQDAALlesgaaiRTAegG---AEHVQPITGDNivnvLDDFRQA--GYTVVTT 275
Cdd:COG0219 12 PQNTGNIIRLCAATGARlhlieplGFSLDDKKL-------KRA--GldyWELVDLTVHDS----WEAFLEAlpGGRLFLF 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1000560672 276 SSEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPN-DLRVKIDGTGNVAGLNISVATGVLLGEWWRQN 343
Cdd:COG0219 79 TTKGTKPYTDVDYQPGDVLLFGRETAGLPEEVLAAPaDQRLRIPMRPGVRSLNLSNAVAIVLYEALRQL 147
|
|
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
208-338 |
4.32e-07 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 48.79 E-value: 4.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 208 PHNLGGMMRSCAHFGVKGVVVQ-------DAALLESGAairtaegGAEHVQPITGDNIVNVLDDFRQAGYTV-VTTSSEQ 279
Cdd:cd18106 11 PGNLGSILRSAAAAGCSKVLLTkgcvdpwEPKVLRAGA-------GAHFRLPIYGNLSWDDIPNYLPDDSKVfLADNNLP 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1000560672 280 GKPLFKT-SLPAKMVLVLGQEYEGLPDAA----RDPNDLRVKIDGTGNVAGLNISVATGVLLGE 338
Cdd:cd18106 84 VQPYDSIdYCSGPIVLVIGGETHGVSPEAyklaHSTGGSRVHIPLANGVDSLNSAVAASILLFE 147
|
|
| SpoU-like |
cd18098 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
198-336 |
3.04e-05 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349971 Cd Length: 138 Bit Score: 43.41 E-value: 3.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 198 CVLALENESNPHNLGGMMRSCAHFGVKGVVVQDAALLESGAAIRTAEgGAEHVQPITGDNIVNVLDDFRQAGYTVVTTSS 277
Cdd:cd18098 1 FAIGIENPKTPKNVGTLWRAAGCLGASFVFTIGARYKRRKQSTDTSK-AWRHIPLFHYDDLEDLAEPLPFGAVLVAVELT 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1000560672 278 EQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNvagLNISVATGVLL 336
Cdd:cd18098 80 EGATPLPDFKHPDRAVYLLGPEDGGLPQEVLARCHHVVYLPTRGS---LNVAVAGSIVL 135
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
197-342 |
5.33e-05 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 43.83 E-value: 5.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 197 DCVLALENESNPHNLGGMMRSCAHFGVKGV--VVQDAALLESGAairTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVT 274
Cdd:PRK11081 19 DLTVCMEQVHKPHNVSAIIRTADAVGVHEVhaVWPGSRMRTMGS---TAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILA 95
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1000560672 275 TS-SEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLLGEWWRQ 342
Cdd:PRK11081 96 THlSDTAVDFREIDYTRPTCILMGQEKTGISQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQ 164
|
|
| SpoU-like_NHR |
cd18108 |
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) ... |
210-338 |
1.78e-04 |
|
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) confers resistance to the thiazole antibiotic nosiheptide via catalyzing 2'O-methylation of 23S rRNA at the nucleotide A1067. NHR is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349981 Cd Length: 144 Bit Score: 41.31 E-value: 1.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1000560672 210 NLGGMMRSCAHFGVKGVVvqdaaLLESGAA------IRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTSSEQGKPL 283
Cdd:cd18108 13 NIGAIVRTSLALGAAGIV-----LVDSDLAtvadrrLLRASRGYVFSLPVVLADREEAVAFLRDNDIPLMTLDADGDVPV 87
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1000560672 284 FK-TSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGVLLGE 338
Cdd:cd18108 88 KElGDRPDRLALVFGSEKGGPSGLFEEAAAGTVSIPMSSSTESLNVSVSAGIALHE 143
|
|
| |
