|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09752 |
PRK09752 |
AIDA-I family autotransporter YfaL; |
1-1250 |
0e+00 |
|
AIDA-I family autotransporter YfaL;
Pssm-ID: 182059 [Multi-domain] Cd Length: 1250 Bit Score: 2269.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1 MRVIFLRKEYLSLLPSMIASLFSANGVAAAIDLCQGYDIKASCHASRQSLSGITQVWSIADGQWLVFSDMTNNASGGAVF 80
Cdd:PRK09752 1 MRIIFLRKEYLSLLPSMIASLFSANGVAAVIDSCQGYDIKASCQASRQSLSGITQDWSIADGQWLVFSDMTNNASGGAVF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 81 LQQGAEFTLSPENETGMTLFANNTVSGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAIDLRVTNA 160
Cdd:PRK09752 81 LQQGAEFTLSPENETGMTLFANNTVSGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 161 VFRNNIANDGKGGAIYTINNDIYLSDDVFNNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIINNTAFTNNTAEGYG 240
Cdd:PRK09752 161 MFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIINNTAFTNNTAEGYG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 241 GAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVD 320
Cdd:PRK09752 241 GAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 321 SIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDKYQNQAELNVGS 400
Cdd:PRK09752 321 SIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDKYQNQAELNVGS 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 401 TQQTFAHSLTGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDAGAVLSLEGDAAD 480
Cdd:PRK09752 401 TQQTFVHSLTGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDDGAVLSLEGDAAD 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 481 LAALQDDPQSIVLNGGMLDLSDFSTWQSGTSYKDGLEVSGSSGTVIGSQDVVDLAGGNDMHIGGDGKDGVYVVIDAGDGQ 560
Cdd:PRK09752 481 LRALQDDPQSIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGDDLHIGGDGKDGVYVVIDAGDGQ 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 561 VSLANDNQYLGTTQIASGTLMVSDNSQLGYTHYNRQVIFTDKPQESVMEITANVDTRSTTTEHGRDIEMRADGEVAVDAG 640
Cdd:PRK09752 561 VSLANNNSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITADVDTRSTTTGHGRDIEMRADGEVAVDAG 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 641 VDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLQGDVADIFPYASSLWVGDGATFVTGADQDI 720
Cdd:PRK09752 641 VDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADIIPYASSLWVGDGATFVTGADQDI 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 721 QSIDATSSGTIDISDGTVLRLTGQDTSVALNASLFNCDGTLVNATDGVTLTGELNTNLETDSLTYLSNVTVNGNLTNTSG 800
Cdd:PRK09752 721 QSIDATSSGTIDISDGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSDVTVNGNLTNTSG 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 801 AVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQ 880
Cdd:PRK09752 801 AVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQ 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 881 FQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPSPPDPDPTPDPDPTQDPDPTPDPEPTPAYQPVLNAKVGG 960
Cdd:PRK09752 881 FQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPSPPDPDPTPDPDPTPDPDPTPDPEPTPAYQPVLNAKVGG 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 961 YLNNLRAANQAFMMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGTDGEWMLGIVGGYSD 1040
Cdd:PRK09752 961 YLNNLRAANQAFMMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGDDGEWMLGIVGGYSD 1040
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1041 NQGDSRSSMTGTRADNQNHGYAVGLTSSWFQHGKQKQGAWLDNWLQYAWFSNDVSEHEDGVDHYHSSGIIASLEAGYQWL 1120
Cdd:PRK09752 1041 NQGDSRSNMTGTRADNQNHGYAVGLTSSWFQHGNQKQGAWLDSWLQYAWFNNDVSEQEDGTDHYHSSGIIASLEAGYQWL 1120
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1121 PGRGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDASTIS 1200
Cdd:PRK09752 1121 PGRGVVIEPQAQVIYQGVQQDDFTAANHARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDGSTIS 1200
|
1210 1220 1230 1240 1250
....*....|....*....|....*....|....*....|....*....|
gi 937821793 1201 DDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW 1250
Cdd:PRK09752 1201 DDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW 1250
|
|
| autotrans_barl |
TIGR01414 |
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, ... |
806-1250 |
1.41e-90 |
|
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 273608 [Multi-domain] Cd Length: 431 Bit Score: 299.30 E-value: 1.41e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 806 NGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDfaadpTQFQNNA 885
Cdd:TIGR01414 1 PGGAFNTLTVNGLYTGNGGFVMNTDLGGDNSQTDRLVVNGNASGTTGVVVNNIGGEGAQTGDGITLVT-----VNGGSDA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 886 QFSLAGsGYVNMGAYDYTLV----EDNNDWYLRSQEvtppsppdpdpTPDPDPTQDPDPTPDPEPTPAYQPVLNAKVGGY 961
Cdd:TIGR01414 76 AFTLAN-GKVDAGAYTYTLYkngtEDNNNWYLTSSL-----------PDLTPPGQQLSPTYRAEAGSYAANANAALFLAE 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 962 LNNLRAANQAFMMERRDHaggdGQTLNLRVIGGDYHYTA-AGQLAQHEDTSTVQLSGDLFSGRWGtDGEWMLGIVGGYSD 1040
Cdd:TIGR01414 144 LDTLRQRMGDLRSAARDA----GNGVWARIFGGDNHLDGdAGAAGYDQNTTGVQLGGDILLAGNA-DGDLHVGLMAGYAK 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1041 NQGDSRSSMTGtrADNQNHGYAVGLTSSWFQHGkqkqGAWLDNWLQYAWFSNDVSEHEDG---VDHYHSSGIIASLEAGY 1117
Cdd:TIGR01414 219 ADIKTRSYKYG--GKGKVDGYGLGLYGTWLQDS----GAYVDGVLQYSRFRNDVSSTGSNgkvSGKYNSNGFTASLEAGY 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1118 QWLPG-RGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLHSEWR----TAVHVIPTLDLNYYHDPH-STE 1191
Cdd:TIGR01414 293 RYNLGgNGWYVEPQAQLSYFGVSGDDYKESNGTRVLGGGGDSLQGRLGLRVGYQfdlgTGRAVKPYLKANVLHEFKgGTG 372
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 937821793 1192 IEEDASTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW 1250
Cdd:TIGR01414 373 VRVNGVTIRNDFSGTRAEYGVGVNAKIKDNLSLYADVDYQKGGKKYTDNQGNLGVRYSF 431
|
|
| AidA |
COG3468 |
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ... |
410-1250 |
2.18e-79 |
|
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442691 [Multi-domain] Cd Length: 846 Bit Score: 279.91 E-value: 2.18e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 410 TGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDAGAVLSLEGDAADLAALQDDPQ 489
Cdd:COG3468 1 TASGGGGGATGLGGGGTGGGGGLGGTGGGNAGLGIGNGGGGGAASGSGAGGVAGNGGGGGGGAGGGGGGAGSGGGLAGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 490 SIVLNGGMLDLSDFSTWQSGTSYKDGLEVSGSSGTVIGSQDVVDLAGGNDMHIGGDGKDGVYVVIDAGDGQVSLANDNQY 569
Cdd:COG3468 81 SGGTGGNSTGGGGGNSGTGGTGGGGGGGGSGNGGGGGGGGGGGGTGGGGGGGTGSAGGGGGGGGGGTGVGGTGAAAAGGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 570 LGTTQIASGTLMVSDNSQLGYTHYNRQVIFTDKPQESVMEITANVDTRSTTTEHGRDIEMRADGEVAVDAGVDTQWGALM 649
Cdd:COG3468 161 TGSGGGGSGGGGGAGGGGGGGAGGSGGAGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGAGGATGGAGSGGNTGGGVGG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 650 ADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLQGDVADIFPYASSLWVGDGATFVTGADQDIQSIDATSSG 729
Cdd:COG3468 241 GGGSAGGTGGGGLTGGGAAGTGGGGGGTGTGSGGGGGGGANGGGSGGGGGASGTGGGGTASTGGGGGGGGGNGGGGGGGS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 730 TIDISDGTVLRLTGQDTSVALNASLFNCDGTLVNATDGVTLTGELNTNLETDSLTYLSNVTVNGNLTNTSGAVSLQNGV- 808
Cdd:COG3468 321 NAGGGSGGGGGGGGGGGGGGTTLNGAGSAGGGTGAALAGTGGSGSGGGGGGGSGGGGGAGGGGANTGSDGVGTGLTTGGt 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 809 ------------------AGDTLTVNGDYTG-GGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGI 869
Cdd:COG3468 401 gnnggggvgggggggltlTGGTLTVNGNYTGnNGTLVLNTVLGDDNSPTDRLVVNGNTSGTTGVRVNNAGGLGAQTVNGI 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 870 KVVDfaadpTQFQNNAQFSLagSGYVNMGAYDYTLV-----EDNNDWYLRSQEVTPPSPpdpdptpdpdptqdpdptpdp 944
Cdd:COG3468 481 EVVE-----VNGASDGAFTL--GGRVVAGAYEYTLYqggsgGDDGNWYLRSTLTPPDPP--------------------- 532
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 945 eptpayQPVLNAKVGGYLNNLRAANQAFMMER----------RDHAGGDGQTLNLRVIGGDYHY-TAAGQLAQHEDTSTV 1013
Cdd:COG3468 533 ------TPVYRPEVPSYLANPAAANGLFELGTlhdrlgerryTDTGESDNSGAWLRVEGGHNRSrDSSGQLDYDSNRYGL 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1014 QLSGDLFSGRWGtDGEWMLGIVGGYSDNQGDSRSSMTGTrADNQNHGYAVGLTSSWFQHgkqkQGAWLDNWLQYAWFSND 1093
Cdd:COG3468 607 QLGGDLLQWEDG-GGRLHVGVMAGYGNGDSDVRSRATGT-GKGDVDGYSLGLYGTWYGN----NGFYVDGVLQYSWFDND 680
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1094 VSEHEDG--VDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLH----S 1167
Cdd:COG3468 681 VSSDDLGgvTGSYDGNGYSASLEAGYPFKLGEGWSLEPQAQLIYQGVDFDDFTDSNGTRVSGDDGDSLQGRLGLRlgyeF 760
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1168 EWRTAVHVIPTLDLNYYHDP-HSTEIEEDASTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSM 1246
Cdd:COG3468 761 HWDDGRALQPYLEANWLHEFlGDNSVTVNGVSFSQDGSGTWGELGLGVTGQLNKNLSLYGDVGYQTGLDGYDSSDTSGNL 840
|
....
gi 937821793 1247 TVKW 1250
Cdd:COG3468 841 GVRY 844
|
|
| PL2_Passenger_AT |
cd01344 |
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of ... |
729-916 |
4.72e-34 |
|
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43, AIDA-1 and IcsA, as well as, the less characterized ShdA, MisL, and BapA autotransporters.
Pssm-ID: 238654 [Multi-domain] Cd Length: 188 Bit Score: 129.34 E-value: 4.72e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 729 GTIDISDGTVL--RLTGQDTSVALNASLFnCDGTLVNATDG-VTLTGELNTNLETDSltylsnVTVNGNLTNtSGAVSLQ 805
Cdd:cd01344 1 GTITGNGGWKLggDLTLGGGALTLTTSLT-LTGTLLTGGAGtLTLDSTSTWNITGTS------TLNVGNLTN-AGTIDLG 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 806 NG-VAGDTLTVNGDYTG-GGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAAdptqFQN 883
Cdd:cd01344 73 NGsPAGGTLTITGNYTGnGGTLRLNTVLGDDDSPTDRLVIDGDASGTTRVAVNNAGGSGATTGNGIEVVEVGG----TSS 148
|
170 180 190
....*....|....*....|....*....|....*...
gi 937821793 884 NAQFSLAgsGYVNMGAYDYTLV-----EDNNDWYLRSQ 916
Cdd:cd01344 149 NGAFSLA--GRVVAGAYEYRLYrggvsGNDGNWYLRSE 184
|
|
| auto_AIDA-I |
NF033176 |
autotransporter adhesin AIDA-I; |
747-1233 |
4.14e-32 |
|
autotransporter adhesin AIDA-I;
Pssm-ID: 380183 [Multi-domain] Cd Length: 1287 Bit Score: 136.33 E-value: 4.14e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 747 SVALNASLFNCDGTLVNATDGVTLTGELNT-------------NLETDS-LTY----LSNVTVNGNLTNTSGAV-SLQNG 807
Cdd:NF033176 767 SAVVNADMAVSQNAYINISDQATINGSVNNkgsvvinnsiingNITNDAdLSFgtakLLSATVNGSLVNNKNIIlNPTKE 846
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 808 VAGDTLTVNgDYTG--GGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADptqfqNNA 885
Cdd:NF033176 847 SAGNTLTVS-NYTGtpGSVISLGGVLEGDNSLTDRLVVKGNTSGQSDIVYVNEGGSGGQTIEGINIISVEGN-----SDA 920
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 886 QFSLAGSgyVNMGAYDYTLVE------DNNDWYLRSQevtppsppdpdptpdpdptqdpdptPDPEPTPAYQPvlnaKVG 959
Cdd:NF033176 921 EFSLKNR--VVAGAYDYTLQKgnvsgtDKKGWYLTSH-------------------------LPTSDTRQYRP----ENG 969
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 960 GYLNNLRAANQAFMM---ERR------DHAGGDGQTLNLRVIGGdyhyTAAGQLAQHEDTSTV-----QLSGDLFSGRWG 1025
Cdd:NF033176 970 SYATNMALANSLFLMdlnERKqfsavnDNTQPESASVWMKITGG----RTSGKLSDGQNKTTTnqfinQLGGDIYKYHAE 1045
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1026 TDGEWMLGIVGGYSDNQGDSRSSMTGTRADNQNHGYAVGLTSSWFQHGKQKQGAWLDNWLQYAWFSNDVSEHEDGVDHYH 1105
Cdd:NF033176 1046 KLGDFTLGIMGGYANAKGKTINHTSKKGARNTLDGYSAGLYGTWYQNGANATGLFAETWMQYNWFNASVKGDGLEEEKYN 1125
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1106 SSGIIASLEAGYQ-----WLPGRGVV----IEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLHSEWR------ 1170
Cdd:NF033176 1126 LNGLTASVGGGYNlnvhtWTSPEGIKgefwLQPHLQAVWMGVTPDTHQEDNGTVVQGTGKNNLQTKAGIRASWKvkssld 1205
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 937821793 1171 --TAVHVIPTLDLNYYHDPHSTEIEEDASTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKG 1233
Cdd:NF033176 1206 kdTGREFRPYIEANWIHNTHEFGVKMSGDNQLLSGSRNQGEIKTGIEGVITQNLSVNGGVAYQAG 1270
|
|
| Autotransporter |
pfam03797 |
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ... |
989-1228 |
1.23e-22 |
|
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.
Pssm-ID: 461054 [Multi-domain] Cd Length: 255 Bit Score: 98.61 E-value: 1.23e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 989 LRVIGGDYHY-TAAGQLAQHEDTSTVQLSGDLFSGrwgtdGEWMLGIVGGYSDnqgdSRSSMTGTRADNQNHGYAVGLTS 1067
Cdd:pfam03797 3 ARGFGGRGKQdGDGGAAGYDADTGGLQVGADYRLG-----DNLRLGVAFGYSR----SDADVDGRGGSGDSDSYSLGLYG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1068 SWFQHGkqkqGAWLDNWLQYAWFSNDVSEHEDGVD-------HYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQ 1140
Cdd:pfam03797 74 TYYGDG----GWYLDGGLGYGWHDNDTRRSVDLGGfsetakgDYDGNGFGASLEAGYRFALGGGWTLEPFAGLAYVRLRL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1141 DDFTAANRA---RVSQSQGDDIQTRLGLHSEWR---TAVHVIPTLDLNYYHDPHSTEIEEDAS-----------TISDDA 1203
Cdd:pfam03797 150 DGFTESGGAaalSVDSQSYDSLTGRLGLRLSYTfdlGGGTLTPYARLGWRHEFGDDDPVTTAAfaglsgagsftVAGADL 229
|
250 260
....*....|....*....|....*
gi 937821793 1204 VKQRGEIKVGVTGNISQRVSLRGSV 1228
Cdd:pfam03797 230 ARDSLELGAGLSAQLSDNLSLYANY 254
|
|
| Autotransporter |
smart00869 |
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ... |
989-1239 |
3.76e-22 |
|
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.
Pssm-ID: 214872 [Multi-domain] Cd Length: 268 Bit Score: 97.64 E-value: 3.76e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 989 LRVIGGDYHYTAAGQLAQHE---DTSTVQLSGDLfsgRWGTDGEWMLGIVGGYSDNQGDSRSSMTGTRADNqnHGYAVGL 1065
Cdd:smart00869 1 GRGLGGFLRQDSSGSGGSAGfdyDSYGLQLGADY---RLSDNGNLSLGFAAGYGNSKVDFSGNKGSGKGDV--DSYGLGL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1066 TSSWFQHgkqkQGAWLDNWLQYAWFSNDVSEHEDGVD------HYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQ 1139
Cdd:smart00869 76 YAGYSLG----NGLYLDAQLGYGRSDNDTKRKVTLGGagrakgSYDGTGYGASLEAGYRFYLGGGLTLTPFAGLAYSRVR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1140 QDDFT----AANRARVSQSQGDDIQTRLGLHSEWRTAVH----VIPTLDLNYYHD---------PHSTEIEEDASTISDD 1202
Cdd:smart00869 152 QDGFTesggGAFGLSVDSQSLDSLSLPLGLRLEYRLALGdgatLTPYLRLAYVHDfyddnpvvtASLLGSGASFTTSGTD 231
|
250 260 270
....*....|....*....|....*....|....*..
gi 937821793 1203 AVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQ 1239
Cdd:smart00869 232 LDRNAAELGLGLSAKLSNGLSLSLNYDGEFGGSSRSH 268
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09752 |
PRK09752 |
AIDA-I family autotransporter YfaL; |
1-1250 |
0e+00 |
|
AIDA-I family autotransporter YfaL;
Pssm-ID: 182059 [Multi-domain] Cd Length: 1250 Bit Score: 2269.58 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1 MRVIFLRKEYLSLLPSMIASLFSANGVAAAIDLCQGYDIKASCHASRQSLSGITQVWSIADGQWLVFSDMTNNASGGAVF 80
Cdd:PRK09752 1 MRIIFLRKEYLSLLPSMIASLFSANGVAAVIDSCQGYDIKASCQASRQSLSGITQDWSIADGQWLVFSDMTNNASGGAVF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 81 LQQGAEFTLSPENETGMTLFANNTVSGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAIDLRVTNA 160
Cdd:PRK09752 81 LQQGAEFTLSPENETGMTLFANNTVSGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 161 VFRNNIANDGKGGAIYTINNDIYLSDDVFNNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIINNTAFTNNTAEGYG 240
Cdd:PRK09752 161 MFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIINNTAFTNNTAEGYG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 241 GAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVD 320
Cdd:PRK09752 241 GAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 321 SIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDKYQNQAELNVGS 400
Cdd:PRK09752 321 SIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDKYQNQAELNVGS 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 401 TQQTFAHSLTGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDAGAVLSLEGDAAD 480
Cdd:PRK09752 401 TQQTFVHSLTGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDDGAVLSLEGDAAD 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 481 LAALQDDPQSIVLNGGMLDLSDFSTWQSGTSYKDGLEVSGSSGTVIGSQDVVDLAGGNDMHIGGDGKDGVYVVIDAGDGQ 560
Cdd:PRK09752 481 LRALQDDPQSIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGDDLHIGGDGKDGVYVVIDAGDGQ 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 561 VSLANDNQYLGTTQIASGTLMVSDNSQLGYTHYNRQVIFTDKPQESVMEITANVDTRSTTTEHGRDIEMRADGEVAVDAG 640
Cdd:PRK09752 561 VSLANNNSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITADVDTRSTTTGHGRDIEMRADGEVAVDAG 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 641 VDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLQGDVADIFPYASSLWVGDGATFVTGADQDI 720
Cdd:PRK09752 641 VDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADIIPYASSLWVGDGATFVTGADQDI 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 721 QSIDATSSGTIDISDGTVLRLTGQDTSVALNASLFNCDGTLVNATDGVTLTGELNTNLETDSLTYLSNVTVNGNLTNTSG 800
Cdd:PRK09752 721 QSIDATSSGTIDISDGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSDVTVNGNLTNTSG 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 801 AVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQ 880
Cdd:PRK09752 801 AVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVLNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQ 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 881 FQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPSPPDPDPTPDPDPTQDPDPTPDPEPTPAYQPVLNAKVGG 960
Cdd:PRK09752 881 FQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPSPPDPDPTPDPDPTPDPDPTPDPEPTPAYQPVLNAKVGG 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 961 YLNNLRAANQAFMMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGTDGEWMLGIVGGYSD 1040
Cdd:PRK09752 961 YLNNLRAANQAFMMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGDDGEWMLGIVGGYSD 1040
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1041 NQGDSRSSMTGTRADNQNHGYAVGLTSSWFQHGKQKQGAWLDNWLQYAWFSNDVSEHEDGVDHYHSSGIIASLEAGYQWL 1120
Cdd:PRK09752 1041 NQGDSRSNMTGTRADNQNHGYAVGLTSSWFQHGNQKQGAWLDSWLQYAWFNNDVSEQEDGTDHYHSSGIIASLEAGYQWL 1120
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1121 PGRGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDASTIS 1200
Cdd:PRK09752 1121 PGRGVVIEPQAQVIYQGVQQDDFTAANHARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDGSTIS 1200
|
1210 1220 1230 1240 1250
....*....|....*....|....*....|....*....|....*....|
gi 937821793 1201 DDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW 1250
Cdd:PRK09752 1201 DDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW 1250
|
|
| autotrans_barl |
TIGR01414 |
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, ... |
806-1250 |
1.41e-90 |
|
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 273608 [Multi-domain] Cd Length: 431 Bit Score: 299.30 E-value: 1.41e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 806 NGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDfaadpTQFQNNA 885
Cdd:TIGR01414 1 PGGAFNTLTVNGLYTGNGGFVMNTDLGGDNSQTDRLVVNGNASGTTGVVVNNIGGEGAQTGDGITLVT-----VNGGSDA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 886 QFSLAGsGYVNMGAYDYTLV----EDNNDWYLRSQEvtppsppdpdpTPDPDPTQDPDPTPDPEPTPAYQPVLNAKVGGY 961
Cdd:TIGR01414 76 AFTLAN-GKVDAGAYTYTLYkngtEDNNNWYLTSSL-----------PDLTPPGQQLSPTYRAEAGSYAANANAALFLAE 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 962 LNNLRAANQAFMMERRDHaggdGQTLNLRVIGGDYHYTA-AGQLAQHEDTSTVQLSGDLFSGRWGtDGEWMLGIVGGYSD 1040
Cdd:TIGR01414 144 LDTLRQRMGDLRSAARDA----GNGVWARIFGGDNHLDGdAGAAGYDQNTTGVQLGGDILLAGNA-DGDLHVGLMAGYAK 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1041 NQGDSRSSMTGtrADNQNHGYAVGLTSSWFQHGkqkqGAWLDNWLQYAWFSNDVSEHEDG---VDHYHSSGIIASLEAGY 1117
Cdd:TIGR01414 219 ADIKTRSYKYG--GKGKVDGYGLGLYGTWLQDS----GAYVDGVLQYSRFRNDVSSTGSNgkvSGKYNSNGFTASLEAGY 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1118 QWLPG-RGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLHSEWR----TAVHVIPTLDLNYYHDPH-STE 1191
Cdd:TIGR01414 293 RYNLGgNGWYVEPQAQLSYFGVSGDDYKESNGTRVLGGGGDSLQGRLGLRVGYQfdlgTGRAVKPYLKANVLHEFKgGTG 372
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 937821793 1192 IEEDASTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW 1250
Cdd:TIGR01414 373 VRVNGVTIRNDFSGTRAEYGVGVNAKIKDNLSLYADVDYQKGGKKYTDNQGNLGVRYSF 431
|
|
| AidA |
COG3468 |
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ... |
410-1250 |
2.18e-79 |
|
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442691 [Multi-domain] Cd Length: 846 Bit Score: 279.91 E-value: 2.18e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 410 TGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDAGAVLSLEGDAADLAALQDDPQ 489
Cdd:COG3468 1 TASGGGGGATGLGGGGTGGGGGLGGTGGGNAGLGIGNGGGGGAASGSGAGGVAGNGGGGGGGAGGGGGGAGSGGGLAGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 490 SIVLNGGMLDLSDFSTWQSGTSYKDGLEVSGSSGTVIGSQDVVDLAGGNDMHIGGDGKDGVYVVIDAGDGQVSLANDNQY 569
Cdd:COG3468 81 SGGTGGNSTGGGGGNSGTGGTGGGGGGGGSGNGGGGGGGGGGGGTGGGGGGGTGSAGGGGGGGGGGTGVGGTGAAAAGGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 570 LGTTQIASGTLMVSDNSQLGYTHYNRQVIFTDKPQESVMEITANVDTRSTTTEHGRDIEMRADGEVAVDAGVDTQWGALM 649
Cdd:COG3468 161 TGSGGGGSGGGGGAGGGGGGGAGGSGGAGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGAGGATGGAGSGGNTGGGVGG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 650 ADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLQGDVADIFPYASSLWVGDGATFVTGADQDIQSIDATSSG 729
Cdd:COG3468 241 GGGSAGGTGGGGLTGGGAAGTGGGGGGTGTGSGGGGGGGANGGGSGGGGGASGTGGGGTASTGGGGGGGGGNGGGGGGGS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 730 TIDISDGTVLRLTGQDTSVALNASLFNCDGTLVNATDGVTLTGELNTNLETDSLTYLSNVTVNGNLTNTSGAVSLQNGV- 808
Cdd:COG3468 321 NAGGGSGGGGGGGGGGGGGGTTLNGAGSAGGGTGAALAGTGGSGSGGGGGGGSGGGGGAGGGGANTGSDGVGTGLTTGGt 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 809 ------------------AGDTLTVNGDYTG-GGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGI 869
Cdd:COG3468 401 gnnggggvgggggggltlTGGTLTVNGNYTGnNGTLVLNTVLGDDNSPTDRLVVNGNTSGTTGVRVNNAGGLGAQTVNGI 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 870 KVVDfaadpTQFQNNAQFSLagSGYVNMGAYDYTLV-----EDNNDWYLRSQEVTPPSPpdpdptpdpdptqdpdptpdp 944
Cdd:COG3468 481 EVVE-----VNGASDGAFTL--GGRVVAGAYEYTLYqggsgGDDGNWYLRSTLTPPDPP--------------------- 532
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 945 eptpayQPVLNAKVGGYLNNLRAANQAFMMER----------RDHAGGDGQTLNLRVIGGDYHY-TAAGQLAQHEDTSTV 1013
Cdd:COG3468 533 ------TPVYRPEVPSYLANPAAANGLFELGTlhdrlgerryTDTGESDNSGAWLRVEGGHNRSrDSSGQLDYDSNRYGL 606
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1014 QLSGDLFSGRWGtDGEWMLGIVGGYSDNQGDSRSSMTGTrADNQNHGYAVGLTSSWFQHgkqkQGAWLDNWLQYAWFSND 1093
Cdd:COG3468 607 QLGGDLLQWEDG-GGRLHVGVMAGYGNGDSDVRSRATGT-GKGDVDGYSLGLYGTWYGN----NGFYVDGVLQYSWFDND 680
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1094 VSEHEDG--VDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLH----S 1167
Cdd:COG3468 681 VSSDDLGgvTGSYDGNGYSASLEAGYPFKLGEGWSLEPQAQLIYQGVDFDDFTDSNGTRVSGDDGDSLQGRLGLRlgyeF 760
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1168 EWRTAVHVIPTLDLNYYHDP-HSTEIEEDASTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSM 1246
Cdd:COG3468 761 HWDDGRALQPYLEANWLHEFlGDNSVTVNGVSFSQDGSGTWGELGLGVTGQLNKNLSLYGDVGYQTGLDGYDSSDTSGNL 840
|
....
gi 937821793 1247 TVKW 1250
Cdd:COG3468 841 GVRY 844
|
|
| PRK15313 |
PRK15313 |
intestinal colonization autotransporter adhesin MisL; |
709-1246 |
3.07e-50 |
|
intestinal colonization autotransporter adhesin MisL;
Pssm-ID: 237940 [Multi-domain] Cd Length: 955 Bit Score: 193.86 E-value: 3.07e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 709 GATFVTgaDQDIQSIDATS-SGTIDISDGTVlRLTGQDTSVALNASLfncdgtLVNATDGvtlTGELNTNLETDSLTYLS 787
Cdd:PRK15313 365 GGRFVI--DGDIRAAGATAaSGTLPQQNSTI-KLNMTDNSRWDGASY------ITSATAG---TGVISVQMSDATWNMTS 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 788 NVTVNgNLTNTSGAV---SLQNGVAGDTLTVNGDYTG-GGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGE 863
Cdd:PRK15313 433 SSTLT-DLTLNSGATinfSHEDGEPWQTLTINEDYVGnGGKLVFNTVLNDDDSETDRLQVLGNTSGNTFVAVNNIGGAGA 511
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 864 PTSTGIKVVDFAADptqfqNNAQFSLAGSgyVNMGAYDYTLVEDNNDWYLRS---------------------------- 915
Cdd:PRK15313 512 QTIEGIEIVNVAGN-----SNGTFEKASR--IVAGAYDYNVVQKGKNWYLTSyiepdepiipdpvdpvipdpvipdpvdp 584
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 916 --------QEVTPPSPPDPDPTPDPDPTQDPDPTPDPEPTPAYQPV----LNAKVGGYLNNLRAANQAFMMERRDHAGGD 983
Cdd:PRK15313 585 dpvdpvipDPVIPDPVDPDPVDPEPVDPVIPDPTIPDIGQSDTPPItehqFRPEVGSYLANNYAANTLFMTRLHDRLGET 664
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 984 GQT-----------LNLRVIGGDYHYT-AAGQLAQHEDTSTVQLSGDLfsGRWGTDG--EWMLGIVGGYSDNQGDSRSSM 1049
Cdd:PRK15313 665 QYTdmltgekkvtsLWMRNVGAHTRFNdGSGQLKTRINSYVLQLGGDL--AQWSTDGldRWHIGAMAGYANSQNRTLSSV 742
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1050 TGTRADNQNHGYAVGLTSSWFQHGKQKQGAWLDNWLQYAWFSNDVSEHEDGVDHYHSSGIIASLEAGYQWLPG----RGV 1125
Cdd:PRK15313 743 SDYHSRGQVTGYSVGLYGTWYANNIDRSGAYVDTWMLYNWFDNKVMGQDQAAEKYKSKGITASVEAGYSFRLGesahQSY 822
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1126 VIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLHS--------EWRTAVHVIPTLDLNYYHDPHSTEIEEDAS 1197
Cdd:PRK15313 823 WLQPKAQVVWMGVQADDNREANGTLVKDDTAGNLLTRMGVKAyinghnaiDDNKSREFQPFVEANWIHNTQPASVKMDDV 902
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 937821793 1198 TISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSM 1246
Cdd:PRK15313 903 SSDMRGTKNIGELKVGIEGQITPRLNVWGNVAQQVGDQGYSNTQGLLGV 951
|
|
| PRK14849 |
PRK14849 |
autotransporter barrel domain-containing lipoprotein; |
725-1250 |
3.94e-47 |
|
autotransporter barrel domain-containing lipoprotein;
Pssm-ID: 184851 [Multi-domain] Cd Length: 1806 Bit Score: 185.71 E-value: 3.94e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 725 ATSSGTIDISDGTVLrlTGQDTSVALNASLFNCDGTLVnATDGVTLTGELNtnLETDSLTYLSNVTVNGNLTNtSGAVSL 804
Cdd:PRK14849 1268 AAYQGTTDIVGGEIA--FGSDSAINMASQHINIHNSGV-MSGNVTTAGDVN--VMPGGTLRVAKTTIGGNLEN-GGTVQM 1341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 805 --QNGVAGDTLTVNGDYTGG-GTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTqf 881
Cdd:PRK14849 1342 nsEGGKPGNVLTVNGNYTGNnGLMTFNATLGGDNSPTDKMNVKGDTQGNTRVRVDNIGGVGAQTVNGIELIEVGGNSA-- 1419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 882 qnnAQFSLAgSGYVNMGAYDYTLVE----DNNDWYLRSQevtppspPDPDPTPDPDPTQDPDPTPDPEPTPAYQPvlnaK 957
Cdd:PRK14849 1420 ---GNFALT-TGTVEAGAYVYTLAKgkgnDEKNWYLTSK-------WDGVTPPDTPDPINNPPVVDPEGPSVYRP----E 1484
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 958 VGGYLNNLRAANQAFMMERRD-----------HAGGDGQTLNLRVIGGDYHYTAA-GQLAQHEDTSTVQLSGDLFSGRWG 1025
Cdd:PRK14849 1485 AGSYISNIAAANSLFSHRLHDrlgepqyidslHSQGSASSMWMRHVGGHERSRAGdGQLNTQANRYVLQLGGDLAQWSSN 1564
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1026 TDGEWMLGIVGGYSDNQGDSRSSMTGTRADNQNHGYAVGLTSSWFQHGKQKQGAWLDNWLQYAWFSNDVSEHEDGVDHYH 1105
Cdd:PRK14849 1565 AQDRWHLGVMAGYANQHSNTQSNRVGYKSDGRISGYSAGLYATWYQNDANKTGAYVDSWALYNWFDNSVSSDNRSADDYD 1644
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1106 SSGIIASLEAGYQWLPG---------RGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLHSEWRT----- 1171
Cdd:PRK14849 1645 SRGVTASVEGGYTFEAGtfsgsegtlNTWYVQPQAQITWMGVKDSDHTRKDGTRIETEGDGNVQTRLGVKTYLNShhqrd 1724
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1172 ---AVHVIPTLDLNYYHDPHSTEIEEDASTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTV 1248
Cdd:PRK14849 1725 dgkQREFQPYIEANWINNSKVYAVKMNGQTVGREGARNLGEVRTGVEAKVNNNLSLWGNVGVQLGDKGYSDTQGMLGVKY 1804
|
..
gi 937821793 1249 KW 1250
Cdd:PRK14849 1805 SW 1806
|
|
| PRK15319 |
PRK15319 |
fibronectin-binding autotransporter adhesin ShdA; |
631-1250 |
2.25e-39 |
|
fibronectin-binding autotransporter adhesin ShdA;
Pssm-ID: 185219 [Multi-domain] Cd Length: 2039 Bit Score: 160.63 E-value: 2.25e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 631 ADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLqgdvadifpyasslWV-GDG 709
Cdd:PRK15319 1428 AHGTFTLGAGDSFEVTSVLGDKTGNGDWDGKSLTKLGAGKLTLSGANTYTGDTNVQEGTL--------------WLsGDG 1493
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 710 ATFVTGADQdiqSIDATSSGTIDISDGTvlrltgqdtsvALNASLFNcDGTLVNAtdgvtltgelntnletDSLTYLSNV 789
Cdd:PRK15319 1494 SIGEMGSQQ---AVNVASGATFGGSNGT-----------TVNGKVTN-EGTLVFG----------------DSEETGAIF 1542
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 790 TVNGNLTN----TSGAVSlqnGVAGDTLTVNGDYTG-GGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSItGIGEP 864
Cdd:PRK15319 1543 TLNGDLINmgtmTSGSSS---STPGNTLYVDGNYTGnGGSLYLNTVLGDDDSATDKLVITGDASGTTDLYINGI-GDGAQ 1618
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 865 TSTGIKVVDFAADPTqfqnNAQFSLAGSgyVNMGAYDYTLV--EDNNDWYLRSQEVTPPSPP------------------ 924
Cdd:PRK15319 1619 TTNGIEVVDVGGVST----SDAFELKNE--VNAGLYTYRLYwnESDNDWYLASKAQSDDDDSggddtpsdggddggnvtp 1692
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 925 -----DPDPTPDPDPTQDPDPTPDPEPTPAYQPVLNAKVGGYLNNLRAANQAFMMERRDHAG-----GDGQTLNLRVIGG 994
Cdd:PRK15319 1693 pddggDGGNVTPPDDGGDGGDVTPPDHGGDVAPQYRADIGAYMGNQWMARNLQMQTLYDREGsqyrnADGSVWARFKAGK 1772
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 995 DYHYTAAGQLAQHEDTSTVQLSGDLFSgrWGTDGE-WMLGIVGGY----SDNQGDSRSSMTGTRADNQNHGYAVGLTSSW 1069
Cdd:PRK15319 1773 AESEAVSGNIDMDSNYSQFQLGGDILA--WGNGQQsVTVGVMASYinadTDSTGNRGADGSQFTSSGNVDGYNLGVYATW 1850
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1070 FQHGKQKQGAWLDNWLQYAWFSNDVSEHEDGVDHYHSSGIIASLEAGYQW----LPGRGVVIEPQAQVIYQGVQQDDFTA 1145
Cdd:PRK15319 1851 FADAQTHSGAYVDSWYQYGFYNNSVESGDAGSESYDSTANAVSLETGYRYdialSNGNTVSLTPQAQVVWQNYSADSVKD 1930
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1146 ANRARVSQSQGDDIQTRLGLHSEWR----TAVHVIPTLDLNYYHDPHSTEIEEDASTISDDAVKQRGEIKVGVTGNISQR 1221
Cdd:PRK15319 1931 NYGTRIDGQDGDSWTTRLGLRVDGKlykgSRTVIQPFAEANWLHTSDDVSVSFDDATVKQDLPANRAELKVGLQADIDKQ 2010
|
650 660
....*....|....*....|....*....
gi 937821793 1222 VSLRGSVAWQKGSDDFAQTAGFLSMTVKW 1250
Cdd:PRK15319 2011 WSVRAQVAGQTGSNDFGDLNGSLNLRYNW 2039
|
|
| PL2_Passenger_AT |
cd01344 |
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of ... |
729-916 |
4.72e-34 |
|
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43, AIDA-1 and IcsA, as well as, the less characterized ShdA, MisL, and BapA autotransporters.
Pssm-ID: 238654 [Multi-domain] Cd Length: 188 Bit Score: 129.34 E-value: 4.72e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 729 GTIDISDGTVL--RLTGQDTSVALNASLFnCDGTLVNATDG-VTLTGELNTNLETDSltylsnVTVNGNLTNtSGAVSLQ 805
Cdd:cd01344 1 GTITGNGGWKLggDLTLGGGALTLTTSLT-LTGTLLTGGAGtLTLDSTSTWNITGTS------TLNVGNLTN-AGTIDLG 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 806 NG-VAGDTLTVNGDYTG-GGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAAdptqFQN 883
Cdd:cd01344 73 NGsPAGGTLTITGNYTGnGGTLRLNTVLGDDDSPTDRLVIDGDASGTTRVAVNNAGGSGATTGNGIEVVEVGG----TSS 148
|
170 180 190
....*....|....*....|....*....|....*...
gi 937821793 884 NAQFSLAgsGYVNMGAYDYTLV-----EDNNDWYLRSQ 916
Cdd:cd01344 149 NGAFSLA--GRVVAGAYEYRLYrggvsGNDGNWYLRSE 184
|
|
| auto_AIDA-I |
NF033176 |
autotransporter adhesin AIDA-I; |
747-1233 |
4.14e-32 |
|
autotransporter adhesin AIDA-I;
Pssm-ID: 380183 [Multi-domain] Cd Length: 1287 Bit Score: 136.33 E-value: 4.14e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 747 SVALNASLFNCDGTLVNATDGVTLTGELNT-------------NLETDS-LTY----LSNVTVNGNLTNTSGAV-SLQNG 807
Cdd:NF033176 767 SAVVNADMAVSQNAYINISDQATINGSVNNkgsvvinnsiingNITNDAdLSFgtakLLSATVNGSLVNNKNIIlNPTKE 846
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 808 VAGDTLTVNgDYTG--GGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADptqfqNNA 885
Cdd:NF033176 847 SAGNTLTVS-NYTGtpGSVISLGGVLEGDNSLTDRLVVKGNTSGQSDIVYVNEGGSGGQTIEGINIISVEGN-----SDA 920
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 886 QFSLAGSgyVNMGAYDYTLVE------DNNDWYLRSQevtppsppdpdptpdpdptqdpdptPDPEPTPAYQPvlnaKVG 959
Cdd:NF033176 921 EFSLKNR--VVAGAYDYTLQKgnvsgtDKKGWYLTSH-------------------------LPTSDTRQYRP----ENG 969
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 960 GYLNNLRAANQAFMM---ERR------DHAGGDGQTLNLRVIGGdyhyTAAGQLAQHEDTSTV-----QLSGDLFSGRWG 1025
Cdd:NF033176 970 SYATNMALANSLFLMdlnERKqfsavnDNTQPESASVWMKITGG----RTSGKLSDGQNKTTTnqfinQLGGDIYKYHAE 1045
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1026 TDGEWMLGIVGGYSDNQGDSRSSMTGTRADNQNHGYAVGLTSSWFQHGKQKQGAWLDNWLQYAWFSNDVSEHEDGVDHYH 1105
Cdd:NF033176 1046 KLGDFTLGIMGGYANAKGKTINHTSKKGARNTLDGYSAGLYGTWYQNGANATGLFAETWMQYNWFNASVKGDGLEEEKYN 1125
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1106 SSGIIASLEAGYQ-----WLPGRGVV----IEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLHSEWR------ 1170
Cdd:NF033176 1126 LNGLTASVGGGYNlnvhtWTSPEGIKgefwLQPHLQAVWMGVTPDTHQEDNGTVVQGTGKNNLQTKAGIRASWKvkssld 1205
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 937821793 1171 --TAVHVIPTLDLNYYHDPHSTEIEEDASTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKG 1233
Cdd:NF033176 1206 kdTGREFRPYIEANWIHNTHEFGVKMSGDNQLLSGSRNQGEIKTGIEGVITQNLSVNGGVAYQAG 1270
|
|
| PL_Passenger_AT |
cd00253 |
Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V ... |
732-918 |
4.70e-29 |
|
Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain of autotransporters forms a pore in the outer membrane through which the N-terminal passenger domain is transported. Following transport, the passenger domain is generally cleaved by an outer membrane protease with the passenger domain either remaining in contact with the surface via a noncovalent interaction with the beta domain or cleaved to release a soluble protein. These proteins are highly diverse and perform a variety of functions that promote virulence, including catalyzing proteolysis, serving as an adhesin, mediating actin-promoted motility, or serving as a cytotoxin. Proteins in this family share similarity in the C-terminal region of the passenger domain as seen in the pertactin structure P.69, a Bordetella pertussis agglutinogen responsible for human pertussis. The P.69 protein consists of a 16-stranded parallel beta-helix with a V-shaped cross-section, and is one of the largest beta-helix known to date.
Pssm-ID: 238156 [Multi-domain] Cd Length: 186 Bit Score: 115.16 E-value: 4.70e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 732 DISDGTVLRLTGQDTSVALNASLFNCDGTLVNATDGVTLTGELNTNletDSLTYLSNVTVNGNLTNTSGAVSLQNG-VAG 810
Cdd:cd00253 2 TLSGNATINGGGDLTLGGGGALTLTGNSVWLGTLQAGGGTVSLNSN---SLWTLTGDSTVNGNLTNSGGTVDFGSAsGAF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 811 DTLTVNGDYTGG-GTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDfaadpTQFQNNAQFSL 889
Cdd:cd00253 79 NTLTVNGNYLGGnGTFVLNTDLGGDNSPTDKLVVTGNASGTTNVAVVNAGGEGASTGDGIELVE-----VNGGSDAAFSL 153
|
170 180 190
....*....|....*....|....*....|...
gi 937821793 890 AgsGYVNMGAYDYTLV----EDNNDWYLRSQEV 918
Cdd:cd00253 154 A--GRVDAGAYEYTLYkggvGNNGNWYLRSTLA 184
|
|
| Autotransporter |
pfam03797 |
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ... |
989-1228 |
1.23e-22 |
|
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.
Pssm-ID: 461054 [Multi-domain] Cd Length: 255 Bit Score: 98.61 E-value: 1.23e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 989 LRVIGGDYHY-TAAGQLAQHEDTSTVQLSGDLFSGrwgtdGEWMLGIVGGYSDnqgdSRSSMTGTRADNQNHGYAVGLTS 1067
Cdd:pfam03797 3 ARGFGGRGKQdGDGGAAGYDADTGGLQVGADYRLG-----DNLRLGVAFGYSR----SDADVDGRGGSGDSDSYSLGLYG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1068 SWFQHGkqkqGAWLDNWLQYAWFSNDVSEHEDGVD-------HYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQ 1140
Cdd:pfam03797 74 TYYGDG----GWYLDGGLGYGWHDNDTRRSVDLGGfsetakgDYDGNGFGASLEAGYRFALGGGWTLEPFAGLAYVRLRL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1141 DDFTAANRA---RVSQSQGDDIQTRLGLHSEWR---TAVHVIPTLDLNYYHDPHSTEIEEDAS-----------TISDDA 1203
Cdd:pfam03797 150 DGFTESGGAaalSVDSQSYDSLTGRLGLRLSYTfdlGGGTLTPYARLGWRHEFGDDDPVTTAAfaglsgagsftVAGADL 229
|
250 260
....*....|....*....|....*
gi 937821793 1204 VKQRGEIKVGVTGNISQRVSLRGSV 1228
Cdd:pfam03797 230 ARDSLELGAGLSAQLSDNLSLYANY 254
|
|
| Autotransporter |
smart00869 |
Autotransporter beta-domain; Secretion of protein products occurs by a number of different ... |
989-1239 |
3.76e-22 |
|
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.
Pssm-ID: 214872 [Multi-domain] Cd Length: 268 Bit Score: 97.64 E-value: 3.76e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 989 LRVIGGDYHYTAAGQLAQHE---DTSTVQLSGDLfsgRWGTDGEWMLGIVGGYSDNQGDSRSSMTGTRADNqnHGYAVGL 1065
Cdd:smart00869 1 GRGLGGFLRQDSSGSGGSAGfdyDSYGLQLGADY---RLSDNGNLSLGFAAGYGNSKVDFSGNKGSGKGDV--DSYGLGL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1066 TSSWFQHgkqkQGAWLDNWLQYAWFSNDVSEHEDGVD------HYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQ 1139
Cdd:smart00869 76 YAGYSLG----NGLYLDAQLGYGRSDNDTKRKVTLGGagrakgSYDGTGYGASLEAGYRFYLGGGLTLTPFAGLAYSRVR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 1140 QDDFT----AANRARVSQSQGDDIQTRLGLHSEWRTAVH----VIPTLDLNYYHD---------PHSTEIEEDASTISDD 1202
Cdd:smart00869 152 QDGFTesggGAFGLSVDSQSLDSLSLPLGLRLEYRLALGdgatLTPYLRLAYVHDfyddnpvvtASLLGSGASFTTSGTD 231
|
250 260 270
....*....|....*....|....*....|....*..
gi 937821793 1203 AVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQ 1239
Cdd:smart00869 232 LDRNAAELGLGLSAKLSNGLSLSLNYDGEFGGSSRSH 268
|
|
| AC_1 |
pfam18883 |
Autochaperone Domain Type 1; This entry represents the autochaperone domain of type 1 (AC-1) ... |
787-904 |
1.59e-15 |
|
Autochaperone Domain Type 1; This entry represents the autochaperone domain of type 1 (AC-1) in the Type Va Secretion System (T5aSS). Autotransporters (ATs) belong to a family of modular proteins secreted by the Type V, subtype a, secretion system (T5aSS) and considered as an important source of virulence factors in lipopolysaccharidic diderm bacteria (archetypical Gram-negative bacteria). The AC of type 1 with beta-fold appears as a prevalent and conserved structural element exclusively associated to beta-helical AT passenger.
Pssm-ID: 465898 [Multi-domain] Cd Length: 114 Bit Score: 73.80 E-value: 1.59e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 787 SNVTvngNLTNTSGAVSLQ--NGVAGDTLTVNGDYTG-GGTLLLDSELNGDDSVSDQLVMNGNTA-GNTTVVVNSITGIG 862
Cdd:pfam18883 1 SNVT---NLTNDNSTINFTapSGASYKTLTVDGDYTGnDGTLALNTYLGGDGSPSDKLVIDGGTAsGTTNLRINNTGGPG 77
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 937821793 863 EPTST-GIKVVDfAADPTQFQNnaqFSLagSGYVNMGAYDYTL 904
Cdd:pfam18883 78 ALTTNdGILVVD-VGGTTSDGA---FRL--AGRAVAGPYEYLL 114
|
|
| PL1_Passenger_AT |
cd01343 |
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of ... |
700-913 |
8.84e-12 |
|
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases, SPATEs (serine protease autotransporters secreted by Enterobacteriaceae), Bordetella pertacins, and nonprotease autotransporters, TibA and similar AIDA-like proteins.
Pssm-ID: 238653 [Multi-domain] Cd Length: 233 Bit Score: 66.22 E-value: 8.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 700 YASSLWVGDGATFVTGadqDIQSIDATSSGTIDISD--GTVLrLTGQDTSVALNASLFNCDGTLVNATDGVTLTGELNTN 777
Cdd:cd01343 26 YGSSVTLTNGAVLDAG---NANLSAAASYATLSGSNirGTVV-LGAGQPLQALAELLLGGNAAWTGAIQGLNATVSLNLN 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 778 letdSLTYLSNVTVNGNLTNTSGAVSLQNGVAGD--TLTVNgDYTGGGTLLLDSELNGDDSvsDQLVMNGNTAGNTTVVV 855
Cdd:cd01343 102 ----SVWTLTGDSNVNNLTLNGGTVDFNGPSAGKfnTLTVN-TLSGNGTFVMRTDLAGGQG--DKLVVTGSATGDFNLLV 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 856 NSITGigEPTS-TGIKVVDfaadpTQFQNNAQFSLAGsGYVNMGAYDYTLVED-NNDWYL 913
Cdd:cd01343 175 VNTGK--EPTSgLNLTLVS-----TPKGGDAEFTLAN-GTVDLGAYRYTLVKDgNGNWTL 226
|
|
| FhaB |
COG3210 |
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ... |
48-896 |
4.84e-10 |
|
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442443 [Multi-domain] Cd Length: 1698 Bit Score: 64.40 E-value: 4.84e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 48 QSLSGITQVWSIADGQWLVFSDMTNNASGGAVFLQQGAEFTLSPENETGMTLFANNTVSGEYNNGGAIFAKENSTLNLTD 127
Cdd:COG3210 434 GITGNGTVTGGTIGGLTGSGTTNGAGLSGNTDVSGTGTVTNSAGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIATG 513
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 128 VIFSGNVAGGYGGAIYSSGTNDTGAIDLRVTNAVFRNNIANDGKGGAIYTINNDIYLSDDVFNNNQAYTSTSYSDGDGGA 207
Cdd:COG3210 514 LTGITAGGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTG 593
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 208 IDVTDNNSDSKHPSGYTIINNTAFTNNTAEGYGGAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAA 287
Cdd:COG3210 594 TNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGG 673
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 288 GGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGlITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNV 367
Cdd:COG3210 674 TTGTVTSGATGGTTGTTLNAATGGTLNNAGNTLTISTGS-ITVTGQIGALANANGDTVTFGNLGTGATLTLNAGVTITSG 752
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 368 GDTHCQDDPQDCYGLTIGSIDKYQNQAELNVGSTQQTFAHSLTGFQNGTLNIDAGGNVTVNQGSFAGTI---EGAGQLTI 444
Cdd:COG3210 753 NAGTLSIGLTANTTASGTTLTLANANGNTSAGATLDNAGAEISIDITADGTITAAGTTAINVTGSGGTItinTATTGLTG 832
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 445 AQNGSYVLAGAQSMALTGDIVVDAGAVLSLEGDAADLAALQDDPQSIVLNGGMLDLSDFSTWQSGTSYKDGLEVSGSSGT 524
Cdd:COG3210 833 TGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAV 912
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 525 VIGSQDVVDLAGGNDMHIGGDGKDGVYVVIDAGDGQVSLANDNQYLGTTQIASGTLMVSDNSQLGYTHYNRQVIFTDKPQ 604
Cdd:COG3210 913 LATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIA 992
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 605 ESVMEITANVDTRSTTTEHGRDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVR 684
Cdd:COG3210 993 ATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVGVNASGISGGNAAALTASGTAGTTGG 1072
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 685 VEEGTLQGDVADIFPYASSLWVGDGATFVTGADQDIQSIDATSSGTIDISDGTVLRLTGQDTSVALNASLFNCDGTLVNA 764
Cdd:COG3210 1073 TAASNGGGGTAQASGAGTTHTLGGITNGGATGTSGGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGTLTGLVAVS 1152
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 765 TDGVTLTGELNTNLETDSLTYLSNVTVNGNLTNTSGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVMN 844
Cdd:COG3210 1153 AVAGGASSASAGDTTAVAAATTTTTGSAINGGADSAATEGTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTASDTGNTTA 1232
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|..
gi 937821793 845 GNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVN 896
Cdd:COG3210 1233 TGGSSAGQTGSFVAAGSASGTGDATTGATAGAVSNGATSTVAGNAGATATGS 1284
|
|
| FhaB |
COG3210 |
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ... |
51-899 |
7.53e-09 |
|
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442443 [Multi-domain] Cd Length: 1698 Bit Score: 60.55 E-value: 7.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 51 SGITQVWSIADGQWLVFSDMTNNASGGAVFLQQGAEFTLSPENETGMTLFANNTVSGEYNNGGAIFAKENSTLNLTDVIF 130
Cdd:COG3210 179 TTGGSLNVVAANPTGVTGVGGALINATAGVLANAGGGTAGGVASANSTLTGGVVAAGTGAGVISTGGTDISSLSVAAGAG 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 131 SGNVAGGYGGAIYSSGTNDTGAIDLRVTNAVFRNNIANDGKGGAIYTINNDIYLSDDVFNNNQAYTSTSYSDGDGGAIDV 210
Cdd:COG3210 259 TGGAGGTGNAGNTTIGTTVTGTNATGSNTAGASSGDTTTNGTSSVTGAGGTGVLGGGTAAGITTTNTVGGNGDGNNTTAN 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 211 TDNNSDSKHPSGYTIINNTAFTNNTAEGYGGAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGF 290
Cdd:COG3210 339 SGAGLVSGGTGGNNGTTGTGAGSGLTGTGNGGGLTTAGAGTVASTVGTATASTGNASSTTVLGSGSLATGNTGTTIAGNG 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 291 MYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDT 370
Cdd:COG3210 419 GSANAGGFTTTGGVLGITGNGTVTGGTIGGLTGSGTTNGAGLSGNTDVSGTGTVTNSAGNTTSATTLAGGGIGTVTTNAT 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 371 HCQDDPQDCYGLTIGSIDKYQNQAELNVGSTQQTFAHSLTGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSY 450
Cdd:COG3210 499 ISNNAGGDANGIATGLTGITAGGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSN 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 451 VLAGAQSMALTGDIVVDAGAVLSLEGDAADLAALQDDPQSIVLNGGMLDLSDFSTWQSGTSYKDGLEVSGSSGTVIGSQD 530
Cdd:COG3210 579 ATTAGNSTSATGGTGTNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANG 658
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 531 VVDLAGGNDMHIGGDGKDGVYVVIDAGDGQVSLANDNQYLGTTQ-----IASGTLMVSDNSQLGYTHYNRQVIFTDKPQE 605
Cdd:COG3210 659 SNTTGVNTAGGTGGGTTGTVTSGATGGTTGTTLNAATGGTLNNAgntltISTGSITVTGQIGALANANGDTVTFGNLGTG 738
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 606 SVMEITANVDTRS------TTTEHGRDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTT 679
Cdd:COG3210 739 ATLTLNAGVTITSgnagtlSIGLTANTTASGTTLTLANANGNTSAGATLDNAGAEISIDITADGTITAAGTTAINVTGSG 818
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 680 QSAVRVEEGTLQGDVADIFPYASSLWVGDGATFVTGADQDIQSIDATSSGTIDISDGTVLRLTGQDTSVALNASLFNCDG 759
Cdd:COG3210 819 GTITINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTN 898
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 760 TLVNATDGVTLTGELNTNLETDSLTYLSNVTVNGNLTNTSGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSD 839
Cdd:COG3210 899 LGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVG 978
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 840 QLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGA 899
Cdd:COG3210 979 TSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAA 1038
|
|
| FhaB |
COG3210 |
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ... |
71-910 |
1.71e-08 |
|
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442443 [Multi-domain] Cd Length: 1698 Bit Score: 59.39 E-value: 1.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 71 TNNASGGAVFLQQGAEFTLSPENETGMTLFANNTVSGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDT 150
Cdd:COG3210 78 TGGIGAAAANTAGTLETGLTSNIGGGSVNGSNSTGNGTLTTTAASATTGNNTGGTTTSSTNTVTTLGGTTTGNTVLSTSG 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 151 GAIDLRVTNAVFRNNIANDGKGGAIYTINNDIYLSDDVFNNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIINNTA 230
Cdd:COG3210 158 AGNNTNTNNSSSGTNIGNSIPTTGGSLNVVAANPTGVTGVGGALINATAGVLANAGGGTAGGVASANSTLTGGVVAAGTG 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 231 FTNNTAEGYGGAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVI 310
Cdd:COG3210 238 AGVISTGGTDISSLSVAAGAGTGGAGGTGNAGNTTIGTTVTGTNATGSNTAGASSGDTTTNGTSSVTGAGGTGVLGGGTA 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 311 GNTENDGAVDSIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDKY 390
Cdd:COG3210 318 AGITTTNTVGGNGDGNNTTANSGAGLVSGGTGGNNGTTGTGAGSGLTGTGNGGGLTTAGAGTVASTVGTATASTGNASST 397
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 391 QNQAELNVGSTQQTFAHSLTGFQNGTLNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDAGA 470
Cdd:COG3210 398 TVLGSGSLATGNTGTTIAGNGGSANAGGFTTTGGVLGITGNGTVTGGTIGGLTGSGTTNGAGLSGNTDVSGTGTVTNSAG 477
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 471 VLSLEGDAADLAALQDDPQSIVLNGGMLDLSDFSTWQSGTSYKDGLEVSGSSGTVIGSQDVVDLAGGNDMHIGGDGKDGV 550
Cdd:COG3210 478 NTTSATTLAGGGIGTVTTNATISNNAGGDANGIATGLTGITAGGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGASGTTA 557
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 551 YVVIDAGDGQVSLANDNQYLGTTQIASGTLMVSDNSQLGYTHYNRQVIFTDKPQesvmeITANVDTRSTTTEHGRDIEMR 630
Cdd:COG3210 558 ASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTGTNSGGTVLSIGTGSAGAT-----GTITLGAGTSGAGANATGGGA 632
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 631 ADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLQGDVADIFPYASSLWVGDGA 710
Cdd:COG3210 633 GLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTGTVTSGATGGTTGTTLNAATGGTLNNAGNTLTISTGS 712
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 711 TFVTGADQDIQSIDATSSGTIDISDGTVLRLTGQDTSVALNASLFNCDGTLVNATDGVTLTGELN-------TNLETDSL 783
Cdd:COG3210 713 ITVTGQIGALANANGDTVTFGNLGTGATLTLNAGVTITSGNAGTLSIGLTANTTASGTTLTLANAngntsagATLDNAGA 792
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 784 TYLSNVTVNGNLTNtSGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGE 863
Cdd:COG3210 793 EISIDITADGTITA-AGTTAINVTGSGGTITINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLA 871
|
810 820 830 840
....*....|....*....|....*....|....*....|....*..
gi 937821793 864 PTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGAYDYTLVEDNND 910
Cdd:COG3210 872 ATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTA 918
|
|
| FhaB |
COG3210 |
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ... |
71-1052 |
1.89e-08 |
|
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442443 [Multi-domain] Cd Length: 1698 Bit Score: 59.01 E-value: 1.89e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 71 TNNASGGAVFLQQGAEFTLSPENETGMTLFANNTVSGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDT 150
Cdd:COG3210 360 GSGLTGTGNGGGLTTAGAGTVASTVGTATASTGNASSTTVLGSGSLATGNTGTTIAGNGGSANAGGFTTTGGVLGITGNG 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 151 GAIDLRVTNAVFRNNIANDGKGGAIYTINNDIYLSDDVFNNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIINNTA 230
Cdd:COG3210 440 TVTGGTIGGLTGSGTTNGAGLSGNTDVSGTGTVTNSAGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIATGLTGITA 519
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 231 FTNNTAEGYGGAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVI 310
Cdd:COG3210 520 GGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTGTNSGGT 599
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 311 GNTENDGAVDSIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDKY 390
Cdd:COG3210 600 VLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTGTVT 679
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 391 QNQAELNVGSTQQTFAHSLTGFQNGTLNIDAGgnvTVNQGSFAGTIEGAGQLTIAQNGSyvlAGAQSMALTGDIVVDAGA 470
Cdd:COG3210 680 SGATGGTTGTTLNAATGGTLNNAGNTLTISTG---SITVTGQIGALANANGDTVTFGNL---GTGATLTLNAGVTITSGN 753
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 471 VLSLEGDAADLAALQ-------------DDPQSIVLNGGMLDLSDFSTWQSGTSYKDGLEVSGSSGTVIGSQDVVDLAGG 537
Cdd:COG3210 754 AGTLSIGLTANTTASgttltlanangntSAGATLDNAGAEISIDITADGTITAAGTTAINVTGSGGTITINTATTGLTGT 833
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 538 NDMHIGGDGKDGVYVVIDAGDGQVSLANDNQYLGTTQIASGTLMVSDNSQLGYTHYNRQVIFTDKPQESVMEITANVDTR 617
Cdd:COG3210 834 GDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVL 913
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 618 STTTEHGRDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLQGDVADI 697
Cdd:COG3210 914 ATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAA 993
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 698 FPYASSLWVGDGATFVTGADQDIQSIDATSSGTIDISDGTVLRLTGQDTSVALNASLFNcDGTLVNATDGVTLTGELNTN 777
Cdd:COG3210 994 TGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVGVNASG-ISGGNAAALTASGTAGTTGG 1072
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 778 LETDSLTYLSNVTVNGNLTNTSGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNS 857
Cdd:COG3210 1073 TAASNGGGGTAQASGAGTTHTLGGITNGGATGTSGGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGTLTGLVAVS 1152
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 858 ITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPSPPDPDPTPDPDPTQD 937
Cdd:COG3210 1153 AVAGGASSASAGDTTAVAAATTTTTGSAINGGADSAATEGTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTASDTGNTTA 1232
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 938 PDPTPDPEPTPAYQPVLNAKVGGYLNNLRAANQAFMMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSG 1017
Cdd:COG3210 1233 TGGSSAGQTGSFVAAGSASGTGDATTGATAGAVSNGATSTVAGNAGATATGSTVDIGSTSATSAGGSLDTTGNTAGANGA 1312
|
970 980 990
....*....|....*....|....*....|....*
gi 937821793 1018 DLFSGRWGTDGEWMLGIVGGYSDNQGDSRSSMTGT 1052
Cdd:COG3210 1313 TVGTGIGGTTATGTAVAAVNSGGVNAGGGTINTTA 1347
|
|
| PRK15319 |
PRK15319 |
fibronectin-binding autotransporter adhesin ShdA; |
299-798 |
9.34e-06 |
|
fibronectin-binding autotransporter adhesin ShdA;
Pssm-ID: 185219 [Multi-domain] Cd Length: 2039 Bit Score: 50.47 E-value: 9.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 299 TFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSGDLVLNADNNDFtGEMQIE-------------NGEVTLGRSNSL- 364
Cdd:PRK15319 596 TFTVDAGSTFTVTSELDETTATSNWNGSKLTKQGDGTLILSNTGNDY-GDTEIDggilaakdaaalgTGDVTIAESATLa 674
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 365 --MNVGDTHCQDDPQDCYG----LTIGSIDKYQNQAELNVGSTQQTFAHSLtgfqnGTLNIDAGGNVTVNQGSFAGTIEG 438
Cdd:PRK15319 675 lsQGTLDNNVTGEGQIVKSgsdeLIVTGDNNYSGGTTISGGTLTADHADSL-----GSGDVDNSGVLKVGEGELENILSG 749
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 439 AGQLTIAQNGSYVLAGAQSMalTGDIVVDAGavlSLEGDAADLAALQDDPQSIVLNGGMLDLSDfSTWQSGTSYKDG--- 515
Cdd:PRK15319 750 SGSLVKTGTGELTLSGDNTY--SGGTTITGG---TLTADHADSLGSGDIDNSGVLKVGEGDLEN-TLSGSGSLVKTGtge 823
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 516 LEVSG----SSGTVIG----SQDVVDLAGGNDMHIGG----------DGKDGVYVVIDAGDGQVSLANDNQYLGTTQIAS 577
Cdd:PRK15319 824 LTLSGgndySGGTTIIggtlTADHADSLGSGDIDNSGvlqvgegelkNTLFGSGSLVKTGTGELTLNGDNDYSGGTTIDD 903
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 578 GTLMVSDNSQLGYTHYNRQVIFTDKPQESVMEITANVDTRSTTTEhgrdiEMRADGEVAVDAGVDTQWGALMADSS---G 654
Cdd:PRK15319 904 GVLIADHADSLGTGAVANSGVLQVGEGELKNTLSGSGSLVKTGTG-----ELTLSGDNSYSGGTTIIGGTLIADHAdslG 978
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 655 QHQDEGSTLTKTGAGTLELTASGttqSAVRVEEGTLQGDVADIFPYASSLWVGDGaTFVTGADQDIQSIDATSSGTIDIS 734
Cdd:PRK15319 979 TGAVANSGVLQVGEGELENTLSG---SGSLVKTGTGELTLGGDNSYSGDTTIADG-TLIAANVNALGSGNIDNSGTLMLD 1054
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 735 DGTVLRL------TGQDTSVALNASLfncDGTLVNATDGVTLTGELNTNLEtDSLTYLSNVTVNGNLTNT 798
Cdd:PRK15319 1055 ANGAFELanitthSGATTALAAGSTL---DAGQLTQEDGSTLSIDLGAATD-DAVITADSVTLGGTLNVT 1120
|
|
| Pertactin |
pfam03212 |
Pertactin; |
812-913 |
1.43e-03 |
|
Pertactin;
Pssm-ID: 460848 [Multi-domain] Cd Length: 121 Bit Score: 39.68 E-value: 1.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 937821793 812 TLTVNGdYTGGGTLLLDSELngDDSVSDQLVMNGNTAGNTTVVVNSiTGiGEPTSTGiKVVDFAADPtqfQNNAQFSLAG 891
Cdd:pfam03212 25 TLTTQT-LSGSGTFVMNADV--ASGTGDQLVVSGNASGQHVLLVRN-TG-SEPASGN-TKLTLVETG---GGDAAFTLGN 95
|
90 100
....*....|....*....|....
gi 937821793 892 SG-YVNMGAYDYTLVEDNN-DWYL 913
Cdd:pfam03212 96 KGgKVDAGTYRYRLTADGNgNWSL 119
|
|
| PATR |
pfam12951 |
Passenger-associated-transport-repeat; This Autotransporter-associated beta strand repeat ... |
663-690 |
6.90e-03 |
|
Passenger-associated-transport-repeat; This Autotransporter-associated beta strand repeat model represents a core 32-residue region of a class of bacterial protein repeat found in one to 30 copies per protein. Most proteins with a copy of this repeat have domains associated with membrane autotransporters (pfam03797). The repeats occur with a periodicity of 60 to 100 residues. A pattern of sequence conservation is that every second residue is well-conserved across most of the domain. These repeats as likely to have a beta-helical structure. This repeat plays a role in the efficient transport of autotransporter virulence factors to the bacterial surface during growth and infection. The repeat is always associated with the passenger domain of the autotransporter. For these reasons it has been coined the Passenger-associated Transport Repeat (PATR). The mechanism by which the PATR motif promotes transport is uncertain but it is likely that the conserved glycines (see HMM Logo) are required for flexibility of folding and that this folding drives secretion. Autotransporters that contain PATR(s) associate with distinct virulence traits such as subtilisin (S8) type protease domains and polymorphic outer-membrane protein repeats, whilst SPATE (S6) type protease and lipase-like autotransporters do not tend to contain PATR motifs.
Pssm-ID: 463760 [Multi-domain] Cd Length: 28 Bit Score: 35.40 E-value: 6.90e-03
10 20
....*....|....*....|....*...
gi 937821793 663 LTKTGAGTLELTASGTTQSAVRVEEGTL 690
Cdd:pfam12951 1 LTKTGAGTLTLTGANTYTGGTTVNAGTL 28
|
|
| |
