NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|838655921|gb|KLW39760|]
View 

alpha/beta hydrolase [Enterobacter sp. MGH119]

Protein Classification

alpha/beta fold hydrolase( domain architecture ID 11426811)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

PubMed:  1409539|12369917

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
39-327 3.40e-35

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


:

Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 127.42  E-value: 3.40e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  39 KQINAGDLNVGYIDIGPkEGQPVILLHGWPYDIHSYEEVAPALAAkGYRVIVPSLRGYGTtrfiSDKTPRNGQPSAMAKD 118
Cdd:COG0596    5 RFVTVDGVRLHYREAGP-DGPPVVLLHGLPGSSYEWRPLIPALAA-GYRVIAPDLRGHGR----SDKPAGGYTLDDLADD 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921 119 IVNLMDALNIKQAVFAGYDWGARTADIVAALWPERVKSLVSVSgylissqaigkqplppkAEVQWWYQFYFATPRGAEGy 198
Cdd:COG0596   79 LAALLDALGLERVVLVGHSMGGMVALELAARHPERVAGLVLVD-----------------EVLAALAEPLRRPGLAPEA- 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921 199 aknthdFARLIWSQASPDWkfsdatfnasaksldnpdhvavtlsnyrwrlglekgeqkydayeqkLATLPNITVPTITIE 278
Cdd:COG0596  141 ------LAALLRALARTDL----------------------------------------------RERLARITVPTLVIW 168
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 838655921 279 GGNNGAPHPVPAAYAGKFTGKYEHRTFgATVGHNPPQEDPQDFVKAVVD 327
Cdd:COG0596  169 GEKDPIVPPALARRLAELLPNAELVVL-PGAGHFPPLEQPEAFAAALRD 216
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
39-327 3.40e-35

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 127.42  E-value: 3.40e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  39 KQINAGDLNVGYIDIGPkEGQPVILLHGWPYDIHSYEEVAPALAAkGYRVIVPSLRGYGTtrfiSDKTPRNGQPSAMAKD 118
Cdd:COG0596    5 RFVTVDGVRLHYREAGP-DGPPVVLLHGLPGSSYEWRPLIPALAA-GYRVIAPDLRGHGR----SDKPAGGYTLDDLADD 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921 119 IVNLMDALNIKQAVFAGYDWGARTADIVAALWPERVKSLVSVSgylissqaigkqplppkAEVQWWYQFYFATPRGAEGy 198
Cdd:COG0596   79 LAALLDALGLERVVLVGHSMGGMVALELAARHPERVAGLVLVD-----------------EVLAALAEPLRRPGLAPEA- 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921 199 aknthdFARLIWSQASPDWkfsdatfnasaksldnpdhvavtlsnyrwrlglekgeqkydayeqkLATLPNITVPTITIE 278
Cdd:COG0596  141 ------LAALLRALARTDL----------------------------------------------RERLARITVPTLVIW 168
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 838655921 279 GGNNGAPHPVPAAYAGKFTGKYEHRTFgATVGHNPPQEDPQDFVKAVVD 327
Cdd:COG0596  169 GEKDPIVPPALARRLAELLPNAELVVL-PGAGHFPPLEQPEAFAAALRD 216
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
60-318 2.79e-26

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 104.51  E-value: 2.79e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921   60 PVILLHGWPYDIHSYEEVAPALAAKGYRVIVPSLRGYGTTRFISDKTprNGQPSAMAKDIVNLMDALNIKQAVFAGYDWG 139
Cdd:pfam00561   2 PVLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKAQD--DYRTDDLAEDLEYILEALGLEKVNLVGHSMG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  140 ARTADIVAALWPERVKSLVSVSGyLISSQAIGKQPLPPKAEVQWWYQFYFA----TPRGAEGYAKNTHDFARLIWSQASP 215
Cdd:pfam00561  80 GLIALAYAAKYPDRVKALVLLGA-LDPPHELDEADRFILALFPGFFDGFVAdfapNPLGRLVAKLLALLLLRLRLLKALP 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  216 DWkfsdaTFNASAKSLDNPDHVAVTLSNYRwrlglekgeqKYDAYEQKLATLPNITVPTITIEGGNNG-APHPVPAAYAG 294
Cdd:pfam00561 159 LL-----NKRFPSGDYALAKSLVTGALLFI----------ETWSTELRAKFLGRLDEPTLIIWGDQDPlVPPQALEKLAQ 223
                         250       260
                  ....*....|....*....|....
gi 838655921  295 KFTGKYEHRTFGAtvGHNPPQEDP 318
Cdd:pfam00561 224 LFPNARLVVIPDA--GHFAFLEGP 245
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
40-173 8.32e-16

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 77.29  E-value: 8.32e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  40 QINAGDLNvgYIDIGPKEGQPVILLHGWPYDIHSYEEVAPALAAkGYRVIVPSLRGYGTtrfiSDKTPRNGQPSAMAKDI 119
Cdd:PRK14875 115 RIGGRTVR--YLRLGEGDGTPVVLIHGFGGDLNNWLFNHAALAA-GRPVIALDLPGHGA----SSKAVGAGSLDELAAAV 187
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 838655921 120 VNLMDALNIKQAVFAGYDWGARTADIVAALWPERVKSLVsvsgyLISSQAIGKQ 173
Cdd:PRK14875 188 LAFLDALGIERAHLVGHSMGGAVALRLAARAPQRVASLT-----LIAPAGLGPE 236
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
39-327 3.40e-35

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 127.42  E-value: 3.40e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  39 KQINAGDLNVGYIDIGPkEGQPVILLHGWPYDIHSYEEVAPALAAkGYRVIVPSLRGYGTtrfiSDKTPRNGQPSAMAKD 118
Cdd:COG0596    5 RFVTVDGVRLHYREAGP-DGPPVVLLHGLPGSSYEWRPLIPALAA-GYRVIAPDLRGHGR----SDKPAGGYTLDDLADD 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921 119 IVNLMDALNIKQAVFAGYDWGARTADIVAALWPERVKSLVSVSgylissqaigkqplppkAEVQWWYQFYFATPRGAEGy 198
Cdd:COG0596   79 LAALLDALGLERVVLVGHSMGGMVALELAARHPERVAGLVLVD-----------------EVLAALAEPLRRPGLAPEA- 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921 199 aknthdFARLIWSQASPDWkfsdatfnasaksldnpdhvavtlsnyrwrlglekgeqkydayeqkLATLPNITVPTITIE 278
Cdd:COG0596  141 ------LAALLRALARTDL----------------------------------------------RERLARITVPTLVIW 168
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 838655921 279 GGNNGAPHPVPAAYAGKFTGKYEHRTFgATVGHNPPQEDPQDFVKAVVD 327
Cdd:COG0596  169 GEKDPIVPPALARRLAELLPNAELVVL-PGAGHFPPLEQPEAFAAALRD 216
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
60-318 2.79e-26

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 104.51  E-value: 2.79e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921   60 PVILLHGWPYDIHSYEEVAPALAAKGYRVIVPSLRGYGTTRFISDKTprNGQPSAMAKDIVNLMDALNIKQAVFAGYDWG 139
Cdd:pfam00561   2 PVLLLHGLPGSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKAQD--DYRTDDLAEDLEYILEALGLEKVNLVGHSMG 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  140 ARTADIVAALWPERVKSLVSVSGyLISSQAIGKQPLPPKAEVQWWYQFYFA----TPRGAEGYAKNTHDFARLIWSQASP 215
Cdd:pfam00561  80 GLIALAYAAKYPDRVKALVLLGA-LDPPHELDEADRFILALFPGFFDGFVAdfapNPLGRLVAKLLALLLLRLRLLKALP 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  216 DWkfsdaTFNASAKSLDNPDHVAVTLSNYRwrlglekgeqKYDAYEQKLATLPNITVPTITIEGGNNG-APHPVPAAYAG 294
Cdd:pfam00561 159 LL-----NKRFPSGDYALAKSLVTGALLFI----------ETWSTELRAKFLGRLDEPTLIIWGDQDPlVPPQALEKLAQ 223
                         250       260
                  ....*....|....*....|....
gi 838655921  295 KFTGKYEHRTFGAtvGHNPPQEDP 318
Cdd:pfam00561 224 LFPNARLVVIPDA--GHFAFLEGP 245
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
40-173 8.32e-16

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 77.29  E-value: 8.32e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  40 QINAGDLNvgYIDIGPKEGQPVILLHGWPYDIHSYEEVAPALAAkGYRVIVPSLRGYGTtrfiSDKTPRNGQPSAMAKDI 119
Cdd:PRK14875 115 RIGGRTVR--YLRLGEGDGTPVVLIHGFGGDLNNWLFNHAALAA-GRPVIALDLPGHGA----SSKAVGAGSLDELAAAV 187
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 838655921 120 VNLMDALNIKQAVFAGYDWGARTADIVAALWPERVKSLVsvsgyLISSQAIGKQ 173
Cdd:PRK14875 188 LAFLDALGIERAHLVGHSMGGAVALRLAARAPQRVASLT-----LIAPAGLGPE 236
PRK00870 PRK00870
haloalkane dehalogenase; Provisional
31-192 1.90e-15

haloalkane dehalogenase; Provisional


Pssm-ID: 179147 [Multi-domain]  Cd Length: 302  Bit Score: 75.39  E-value: 1.90e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  31 YASAFNQVKQINAGDLNVGYIDIGPKEGQPVILLHG---WPYdihSYEEVAPALAAKGYRVIVPSLRGYGTtrfiSDKtp 107
Cdd:PRK00870  19 FAPHYVDVDDGDGGPLRMHYVDEGPADGPPVLLLHGepsWSY---LYRKMIPILAAAGHRVIAPDLIGFGR----SDK-- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921 108 rngqPSAMAkD---------IVNLMDALNIKQAVFAGYDWGARTADIVAALWPERVKSLVSVSGYLissqAIGKQPLPPK 178
Cdd:PRK00870  90 ----PTRRE-DytyarhvewMRSWFEQLDLTDVTLVCQDWGGLIGLRLAAEHPDRFARLVVANTGL----PTGDGPMPDA 160
                        170
                 ....*....|....
gi 838655921 179 AEVqwWYQFYFATP 192
Cdd:PRK00870 161 FWA--WRAFSQYSP 172
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
60-190 6.50e-10

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 58.47  E-value: 6.50e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  60 PVILLHGWPYDIHSYEEVAPALAAKGYRVIVPSLRGYGTTrfiSDKTPRNGQPSAMAKDIVNLMDALNI---KQAVFAGY 136
Cdd:COG2267   30 TVVLVHGLGEHSGRYAELAEALAAAGYAVLAFDLRGHGRS---DGPRGHVDSFDDYVDDLRAALDALRArpgLPVVLLGH 106
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 838655921 137 DWGARTADIVAALWPERVKSLVsvsgylISSQAIGKQPLPPkAEVQWWYQFYFA 190
Cdd:COG2267  107 SMGGLIALLYAARYPDRVAGLV------LLAPAYRADPLLG-PSARWLRALRLA 153
PRK10673 PRK10673
esterase;
55-160 8.44e-09

esterase;


Pssm-ID: 182637 [Multi-domain]  Cd Length: 255  Bit Score: 55.51  E-value: 8.44e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  55 PKEGQPVILLHGWPYDIHSYEEVAPALAaKGYRVIVPSLRGYGttrfISDKTPRNGQPsAMAKDIVNLMDALNIKQAVFA 134
Cdd:PRK10673  13 PHNNSPIVLVHGLFGSLDNLGVLARDLV-NDHDIIQVDMRNHG----LSPRDPVMNYP-AMAQDLLDTLDALQIEKATFI 86
                         90       100
                 ....*....|....*....|....*.
gi 838655921 135 GYDWGARTADIVAALWPERVKSLVSV 160
Cdd:PRK10673  87 GHSMGGKAVMALTALAPDRIDKLVAI 112
PRK03592 PRK03592
haloalkane dehalogenase; Provisional
32-158 1.05e-08

haloalkane dehalogenase; Provisional


Pssm-ID: 235135  Cd Length: 295  Bit Score: 55.39  E-value: 1.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  32 ASAFNQVKQINAGDLNVGYIDIGpkEGQPVILLHGWPYDIHSYEEVAPALAAKGyRVIVPSLRGYGTtrfiSDKTPRNGQ 111
Cdd:PRK03592   3 VEPPGEMRRVEVLGSRMAYIETG--EGDPIVFLHGNPTSSYLWRNIIPHLAGLG-RCLAPDLIGMGA----SDKPDIDYT 75
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 838655921 112 PSAMAKDIVNLMDALNIKQAVFAGYDWGARTADIVAALWPERVKSLV 158
Cdd:PRK03592  76 FADHARYLDAWFDALGLDDVVLVGHDWGSALGFDWAARHPDRVRGIA 122
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
55-163 4.28e-08

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 53.10  E-value: 4.28e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  55 PKEGQP---VILLHGWPYDI-HSYEEVAPALAAKGYRVIVPSLRGYGTTrfisdktpRNGQPSAMAKDIVNLMDALnIKQ 130
Cdd:COG1506   17 PADGKKypvVVYVHGGPGSRdDSFLPLAQALASRGYAVLAPDYRGYGES--------AGDWGGDEVDDVLAAIDYL-AAR 87
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 838655921 131 AVF-------AGYDWGARTADIVAALWPERVKSLVSVSGY 163
Cdd:COG1506   88 PYVdpdrigiYGHSYGGYMALLAAARHPDRFKAAVALAGV 127
PRK05855 PRK05855
SDR family oxidoreductase;
43-162 2.05e-06

SDR family oxidoreductase;


Pssm-ID: 235628 [Multi-domain]  Cd Length: 582  Bit Score: 49.21  E-value: 2.05e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  43 AGDLNVGYIDIGPKEGQPVILLHGWPYDIHSYEEVAPALAAKgYRVIVPSLRGYGTtrfiSDKtPRNGQP---SAMAKDI 119
Cdd:PRK05855  10 SDGVRLAVYEWGDPDRPTVVLVHGYPDNHEVWDGVAPLLADR-FRVVAYDVRGAGR----SSA-PKRTAAytlARLADDF 83
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 838655921 120 VNLMDALNIKQAV-FAGYDWGArtadivAALW--------PERVKSLVSVSG 162
Cdd:PRK05855  84 AAVIDAVSPDRPVhLLAHDWGS------IQGWeavtrpraAGRIASFTSVSG 129
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
55-183 5.42e-06

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 46.88  E-value: 5.42e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  55 PKEGQP---VILLHGWPYDIHSYEEVAPALAAKGYRVIVPSLRGYGTTRFISDKTPRNGQ---PSAMAKDIVNLMDAL-- 126
Cdd:COG0412   23 PAGGGPrpgVVVLHEIFGLNPHIRDVARRLAAAGYVVLAPDLYGRGGPGDDPDEARALMGaldPELLAADLRAALDWLka 102
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 838655921 127 ----NIKQAVFAGYDWGARTADIVAALWPeRVKSLVSVSGYLISSQAIGKQPlPPKAEVQW 183
Cdd:COG0412  103 qpevDAGRVGVVGFCFGGGLALLAAARGP-DLAAAVSFYGGLPADDLLDLAA-RIKAPVLL 161
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
61-324 9.40e-06

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 45.93  E-value: 9.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921   61 VILLHGWPYDIHSYeevaPALAAKGYRVIVPSLRGYGTtrfisdkTPRNGQPSAMAKDIVNLMDAL-NIKQAVFAGYDWG 139
Cdd:pfam12697   1 VVLVHGAGLSAAPL----AALLAAGVAVLAPDLPGHGS-------SSPPPLDLADLADLAALLDELgAARPVVLVGHSLG 69
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  140 ArtadIVAAlwpeRVKSLVSVSGYLISSqaigkqPLPPKAEVQWWYQFYFATPRGAEGYAKNTHDFARLIWSQASPDWKF 219
Cdd:pfam12697  70 G----AVAL----AAAAAALVVGVLVAP------LAAPPGLLAALLALLARLGAALAAPAWLAAESLARGFLDDLPADAE 135
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  220 SDATFNASAKSLDNPDHVAvtlsnyrwrlglekgeqkydayeqkLATLPNITVPTITIEGGNNGAPHPVpAAYAGKFTGK 299
Cdd:pfam12697 136 WAAALARLAALLAALALLP-------------------------LAAWRDLPVPVLVLAEEDRLVPELA-QRLLAALAGA 189
                         250       260
                  ....*....|....*....|....*
gi 838655921  300 YEHRTFGAtvGHNpPQEDPQDFVKA 324
Cdd:pfam12697 190 RLVVLPGA--GHL-PLDDPEEVAEA 211
PLN02578 PLN02578
hydrolase
57-158 5.81e-05

hydrolase


Pssm-ID: 215315 [Multi-domain]  Cd Length: 354  Bit Score: 44.45  E-value: 5.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  57 EGQPVILLHG-------WPYDIhsyeevaPALaAKGYRVIVPSLRGYGttrfISDKTPRNGQPSAMAKDIVNLMDALNIK 129
Cdd:PLN02578  85 EGLPIVLIHGfgasafhWRYNI-------PEL-AKKYKVYALDLLGFG----WSDKALIEYDAMVWRDQVADFVKEVVKE 152
                         90       100
                 ....*....|....*....|....*....
gi 838655921 130 QAVFAGYDWGARTADIVAALWPERVKSLV 158
Cdd:PLN02578 153 PAVLVGNSLGGFTALSTAVGYPELVAGVA 181
YpfH COG0400
Predicted esterase [General function prediction only];
54-166 1.05e-04

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 42.59  E-value: 1.05e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  54 GPKEGQPVILLHGWPYDIHSYEEVAPALAAKGYRVIVP---SLRGYGTTRF--ISDKTPRNGQPS--AMAKDIVNLMDAL 126
Cdd:COG0400    1 GGPAAPLVVLLHGYGGDEEDLLPLAPELALPGAAVLAPrapVPEGPGGRAWfdLSFLEGREDEEGlaAAAEALAAFIDEL 80
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 838655921 127 NIK------QAVFAGYDWGARTADIVAALWPERVKSLVSVSGYLIS 166
Cdd:COG0400   81 EARygidpeRIVLAGFSQGAAMALSLALRRPELLAGVVALSGYLPG 126
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
61-99 2.92e-04

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 41.85  E-value: 2.92e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 838655921  61 VILLHGW---PYDIHsyeEVAPALAAKGYRVIVPSLRGYGTT 99
Cdd:COG1647   18 VLLLHGFtgsPAEMR---PLAEALAKAGYTVYAPRLPGHGTS 56
PLN03084 PLN03084
alpha/beta hydrolase fold protein; Provisional
50-110 3.41e-04

alpha/beta hydrolase fold protein; Provisional


Pssm-ID: 178633  Cd Length: 383  Bit Score: 42.18  E-value: 3.41e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 838655921  50 YIDIGPKEGQPVILLHGWPYDIHSYEEVAPALaAKGYRVIVPSLRGYGttrfISDK-TPRNG 110
Cdd:PLN03084 119 CVESGSNNNPPVLLIHGFPSQAYSYRKVLPVL-SKNYHAIAFDWLGFG----FSDKpQPGYG 175
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
43-163 5.31e-04

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 41.05  E-value: 5.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  43 AGDLnvgYIDIGPKEGQPVILL-HGWPYDIHSYEEVAPALAAKGYRVIVPSLRGYGTtrfiSDKTPRNgQPSAMAKDIVN 121
Cdd:COG1073   24 AGDL---YLPAGASKKYPAVVVaHGNGGVKEQRALYAQRLAELGFNVLAFDYRGYGE----SEGEPRE-EGSPERRDARA 95
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 838655921 122 LMDALNIKQAV------FAGYDWGARTAdIVAALWPERVKSLVSVSGY 163
Cdd:COG1073   96 AVDYLRTLPGVdperigLLGISLGGGYA-LNAAATDPRVKAVILDSPF 142
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
60-162 4.38e-03

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 36.35  E-value: 4.38e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 838655921  60 PVILLHGWPYDIHSYEEVAPALAAKGYRVIVPSLrgygttrfisdkTPRNGQPSAMAKDIVNLMDalnikqAVFAGYdwG 139
Cdd:COG1075    7 PVVLVHGLGGSAASWAPLAPRLRAAGYPVYALNY------------PSTNGSIEDSAEQLAAFVD------AVLAAT--G 66
                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 838655921 140 ARTADIVA--------------ALWPERVKSLVSVSG 162
Cdd:COG1075   67 AEKVDLVGhsmgglvaryylkrLGGAAKVARVVTLGT 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH