|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
17-825 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1270.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 17 KGIVSRSITTEMRESYLDYAMSVITARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDVLGKYHPHGDTSV 96
Cdd:PRK05560 3 DRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSAV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 97 YDAMVKMAQDFTMRYPLIIGQGNFGSIDGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAANYDNTKTEPTVLPAAIPN 176
Cdd:PRK05560 83 YDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPN 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 177 LLLNGTLGIAVGMATNIPPHNLREVCEATVHLIENPEATTDDLLKFVQGPDFPTGCIAFNQKDMAHAYATGRGPVVVRGD 256
Cdd:PRK05560 163 LLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVMRAK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 257 AEIvEGKKGDYQIIITSIPFRVNKSDLLTKVADLVHEKKLEGVRDIRDESTKD-IRVVVELKNNANAQTVLNYLYKHTQL 335
Cdd:PRK05560 243 AEI-EEIKGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDgMRIVIELKRDAVPEVVLNNLYKHTQL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 336 EETFHYNVVALVDGVPQTLSLKALLEYFILHRKEIVTRRTRFDLAKAQAREHILLGLKKALDHIDEIIKLIKKSKDVDDA 415
Cdd:PRK05560 322 QTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTPAEA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 416 RQGLMKTFKFSEIQAGAILDMRLQKLAGLERKKVEDELKEVQMLIEELTSLLKSPKKLMDLIKKEIREVIEKYGDDRRTK 495
Cdd:PRK05560 402 KEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGDPRRTE 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 496 IVKRGATIlSAEDLIADEESVLVLTSGGYIKRTNPAEYRRQRRGGVGVVDLDTKEEDFVTQFLTASAHSDLLFFSDRGKV 575
Cdd:PRK05560 482 IIEGEGDI-DDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFTNRGRV 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 576 YQLKMYDLPEGKRATKGKSIMNYLSLEGSENITSILAMPKEKkivEGLSLIMTTRDGTVKKSAANKFYEVRRSGLIAINL 655
Cdd:PRK05560 561 YRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFD---DDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAINL 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 656 DKGDALISAQFVRKGDSVVLVTTKGLAIRFDEKNVREMGRQAAGVRGMKLRSGDAIVGTGVVPKEakDAELLVLSSTGYG 735
Cdd:PRK05560 638 DEGDELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVRGIKLREGDEVVSMDVVRED--SQEILTVTENGYG 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 736 KKTKLSEYKIQGRGGSGIKTMSITTKTKQLVGGAVLTKGGELVAMSKKSQTIRTGLDEIPTLSRATQGVRVMKMREGDQV 815
Cdd:PRK05560 716 KRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLIRTRVSEISITGRNTQGVRLIRLDEGDKV 795
|
810
....*....|
gi 818893435 816 ASFVVFETPD 825
Cdd:PRK05560 796 VSVARVAEEE 805
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
15-818 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1266.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 15 PVKGIVSRSITTEMRESYLDYAMSVITARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDVLGKYHPHGDT 94
Cdd:COG0188 6 PAERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYHPHGDS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 95 SVYDAMVKMAQDFTMRYPLIIGQGNFGSIDGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAANYDNTKTEPTVLPAAI 174
Cdd:COG0188 86 AVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTVLPARF 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 175 PNLLLNGTLGIAVGMATNIPPHNLREVCEATVHLIENPEATTDDLLKFVQGPDFPTGCIAFNQKDMAHAYATGRGPVVVR 254
Cdd:COG0188 166 PNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRGSIRVR 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 255 GDAEIVEGKKGDYQIIITSIPFRVNKSDLLTKVADLVHEKKLEGVRDIRDESTKD-IRVVVELKNNANAQTVLNYLYKHT 333
Cdd:COG0188 246 AKAEIEELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDgMRIVIELKRDANPEVVLNQLYKHT 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 334 QLEETFHYNVVALVDGVPQTLSLKALLEYFILHRKEIVTRRTRFDLAKAQAREHILLGLKKALDHIDEIIKLIKKSKDVD 413
Cdd:COG0188 326 QLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIRASKDPD 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 414 DARQGLMKTFKFSEIQAGAILDMRLQKLAGLERKKVEDELKEVQMLIEELTSLLKSPKKLMDLIKKEIREVIEKYGDDRR 493
Cdd:COG0188 406 EAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELLEIKKKYGDERR 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 494 TKIVKRGATIlSAEDLIADEESVLVLTSGGYIKRTNPAEYRRQRRGGVGVVDLDTKEEDFVTQFLTASAHSDLLFFSDRG 573
Cdd:COG0188 486 TEIEEAEGEI-DIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDFVEHLFVASTHDTLLFFTNKG 564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 574 KVYQLKMYDLPEGKRATKGKSIMNYLSLEGSENITSILAMPKEKkivEGLSLIMTTRDGTVKKSAANKFYEVRRSGLIAI 653
Cdd:COG0188 565 RVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFD---EDKYLLFATKKGTVKKTPLSDFSNIRKNGIIAI 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 654 NLDKGDALISAQFVRKGDSVVLVTTKGLAIRFDEKNVREMGRQAAGVRGMKLRSGDAIVGTGVVPkeaKDAELLVLSSTG 733
Cdd:COG0188 642 NLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTARGVRGIRLKEGDEVVGMAVVD---EEDDLLTVTENG 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 734 YGKKTKLSEYKIQGRGGSGIKTMSITTKTKQLVGGAVLTKGGELVAMSKKSQTIRTGLDEIPTLSRATQGVRVMKMREGD 813
Cdd:COG0188 719 YGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNTQGVRLIRLDEGD 798
|
....*
gi 818893435 814 QVASF 818
Cdd:COG0188 799 KVVSV 803
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
19-817 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1062.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 19 IVSRSITTEMRESYLDYAMSVITARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDVLGKYHPHGDTSVYD 98
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 99 AMVKMAQDFTMRYPLIIGQGNFGSIDGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAANYDNTKTEPTVLPAAIPNLL 178
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 179 LNGTLGIAVGMATNIPPHNLREVCEATVHLIENPEATTDDLLKFVQGPDFPTGCIAFNQKDMAHAYATGRGPVVVRGDAE 258
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 259 IVEGKKGDYQIIITSIPFRVNKSDLLTKVADLVHEKKLEGVRDIRDESTKD-IRVVVELKNNANAQTVLNYLYKHTQLEE 337
Cdd:TIGR01063 241 IEEDSKGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREgIRIVIELKRDAVAEVVLNNLYKQTQLQV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 338 TFHYNVVALVDGVPQTLSLKALLEYFILHRKEIVTRRTRFDLAKAQAREHILLGLKKALDHIDEIIKLIKKSKDVDDARQ 417
Cdd:TIGR01063 321 SFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAKT 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 418 GLMKTFKFSEIQAGAILDMRLQKLAGLERKKVEDELKEVQMLIEELTSLLKSPKKLMDLIKKEIREVIEKYGDDRRTKIV 497
Cdd:TIGR01063 401 RLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPRRTEIV 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 498 KRGATILSAEDLIADEESVLVLTSGGYIKRTNPAEYRRQRRGGVGVVDLDTKEEDFVTQFLTASAHSDLLFFSDRGKVYQ 577
Cdd:TIGR01063 481 YDESEDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVYW 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 578 LKMYDLPEGKRATKGKSIMNYLSLEGSENITSILAMpkeKKIVEGLSLIMTTRDGTVKKSAANKFYEVRRSGLIAINLDK 657
Cdd:TIGR01063 561 LKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSV---KEFDDGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKLDD 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 658 GDALISAQFVRKGDSVVLVTTKGLAIRFDEKNVREMGRQAAGVRGMKLRSGDAIVGTGVVPKEAKdaeLLVLSSTGYGKK 737
Cdd:TIGR01063 638 GDELISVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIKLKNEDFVVSLLVVSEESY---LLIVTENGYGKR 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 738 TKLSEYKIQGRGGSGIKTMSITTKTKQLVGGAVLTKGGELVAMSKKSQTIRTGLDEIPTLSRATQGVRVMKMREGDQVAS 817
Cdd:TIGR01063 715 TSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLIRLDEDDKLVS 794
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
42-484 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 638.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 42 ARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDVLGKYHPHGDTSVYDAMVKMAQDFTMRYPLIIGQGNFG 121
Cdd:cd00187 2 GRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNFG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 122 SIDGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAANYDNTKTEPTVLPAAIPNLLLNGTLGIAVGMATNIPPHNLREV 201
Cdd:cd00187 82 SRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLREV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 202 CEATVHLIENPEATTDDLLKFVQGPDFPTGCIAFNQKDMAHAYATGRGPVVVRGDAEIvEGKKGDYQIIITSIPFRVNKS 281
Cdd:cd00187 162 IDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEI-EDDEGRNTIEITELPYQVNKA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 282 DLLTKVADLVHEKKLEGVRDIRDESTKD-IRVVVELKNNANAQTVLNYLYKHTQLEETFHYNVVALV-DGVPQTLSLKAL 359
Cdd:cd00187 241 KLKEKIAELVKDKKIEGISDVRDESDREgIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDpNGRPKKLNLKEI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 360 LEYFILHRKEIVTRRTRFDLAKAQAREHILLGLKKALDHIDEIIKLIKKSkdvDDARQGLMKTF---KFSEIQAGAILDM 436
Cdd:cd00187 321 LQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELeklGFSEIQADAILDM 397
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 818893435 437 RLQKLAGLERKKVEDELKEVQMLIEELTSLLKSPKKLMDLIKKEIREV 484
Cdd:cd00187 398 RLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
43-482 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 609.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 43 RALPDVRDGLKPVHRRILYAMQEaGLTVSAKTRKSATVVGDVLGKYHPHGDTSVYDAMVKMAQDFTMRYPLIIGQGNFGS 122
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFE-LLNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 123 -IDGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAANYDNTKTEPTVLPAAIPNLLLNGTLGIAVGMATNIPPHNLREV 201
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 202 CEATVHLIENPEATtdDLLKFVQGPDFPTGCIAFNQKDMAHAYATGRGPVVVRGDAEIVEGKkgdyQIIITSIPFRVNKS 281
Cdd:pfam00521 160 IDALIALLDGPEAT--LLMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIEDRK----TIVITELPYGVWTS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 282 DLLTKVADLVHEKKLEGVRDIRDESTKDIRVVVELKNNANAQTVLNYLYKHTQLEETFHYNVVALVDGVPQTLSLKALLE 361
Cdd:pfam00521 234 DLIEKIEELVKNGKIKGISDIRDESDRGVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKEILK 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 362 YFILHRKEIVTRRTRFDLAKAQAREHILLGLKKALDHIDEIIKLIKKSKDVDDARQGLMKtfKFSEIQAGAILDMRLQKL 441
Cdd:pfam00521 314 EFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIE--ELSEIQADYLLDMRLRRL 391
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 818893435 442 AGLERKKVEDELKEVQMLIEELTSLLKSPKKLMDLIKKEIR 482
Cdd:pfam00521 392 TKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
22-474 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 602.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 22 RSITTEMRESYLDYAMSVITARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDVLGKYHPHGDTSVYDAMV 101
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 102 KMAQDFTMRYPLIIGQGNFGSI-DGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAANYDNTKTEPTVLPAAIPNLLLN 180
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 181 GTLGIAVGMATNIPPHNLREVCEATVHLIENPEATTDDLLKFVQGPDFPTGCIAFnqkdmahayatGRGPVVVRGDAEIV 260
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGKIEIE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 261 EGKkgdyQIIITSIPFRVNKSDLLTKVADLVHEKKLEGVRDIRDES--TKDIRVVVELKNNANAQTVLNYLYKHTQLEET 338
Cdd:smart00434 230 DDN----TIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShdRTGVRIVIELKRGAMAEVVLNGLYKLTKLQTT 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 339 FHYNVVALVD-GVPQTLSLKALLEYFILHRKEIVTRRTRFDLAKAQ-AREHILLGLKKALDHIDEIIKLIKKSKD-VDDA 415
Cdd:smart00434 306 FSINMLALFDnGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKDlAKEA 385
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 818893435 416 RQGLMKTFKFSEIQAGAILDMRLQKLAGLERKKVEDELKEVQMLIEELTSLLKSPKKLM 474
Cdd:smart00434 386 KEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
17-825 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1270.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 17 KGIVSRSITTEMRESYLDYAMSVITARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDVLGKYHPHGDTSV 96
Cdd:PRK05560 3 DRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSAV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 97 YDAMVKMAQDFTMRYPLIIGQGNFGSIDGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAANYDNTKTEPTVLPAAIPN 176
Cdd:PRK05560 83 YDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPN 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 177 LLLNGTLGIAVGMATNIPPHNLREVCEATVHLIENPEATTDDLLKFVQGPDFPTGCIAFNQKDMAHAYATGRGPVVVRGD 256
Cdd:PRK05560 163 LLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVMRAK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 257 AEIvEGKKGDYQIIITSIPFRVNKSDLLTKVADLVHEKKLEGVRDIRDESTKD-IRVVVELKNNANAQTVLNYLYKHTQL 335
Cdd:PRK05560 243 AEI-EEIKGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDgMRIVIELKRDAVPEVVLNNLYKHTQL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 336 EETFHYNVVALVDGVPQTLSLKALLEYFILHRKEIVTRRTRFDLAKAQAREHILLGLKKALDHIDEIIKLIKKSKDVDDA 415
Cdd:PRK05560 322 QTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTPAEA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 416 RQGLMKTFKFSEIQAGAILDMRLQKLAGLERKKVEDELKEVQMLIEELTSLLKSPKKLMDLIKKEIREVIEKYGDDRRTK 495
Cdd:PRK05560 402 KEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGDPRRTE 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 496 IVKRGATIlSAEDLIADEESVLVLTSGGYIKRTNPAEYRRQRRGGVGVVDLDTKEEDFVTQFLTASAHSDLLFFSDRGKV 575
Cdd:PRK05560 482 IIEGEGDI-DDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFTNRGRV 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 576 YQLKMYDLPEGKRATKGKSIMNYLSLEGSENITSILAMPKEKkivEGLSLIMTTRDGTVKKSAANKFYEVRRSGLIAINL 655
Cdd:PRK05560 561 YRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFD---DDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAINL 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 656 DKGDALISAQFVRKGDSVVLVTTKGLAIRFDEKNVREMGRQAAGVRGMKLRSGDAIVGTGVVPKEakDAELLVLSSTGYG 735
Cdd:PRK05560 638 DEGDELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVRGIKLREGDEVVSMDVVRED--SQEILTVTENGYG 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 736 KKTKLSEYKIQGRGGSGIKTMSITTKTKQLVGGAVLTKGGELVAMSKKSQTIRTGLDEIPTLSRATQGVRVMKMREGDQV 815
Cdd:PRK05560 716 KRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLIRTRVSEISITGRNTQGVRLIRLDEGDKV 795
|
810
....*....|
gi 818893435 816 ASFVVFETPD 825
Cdd:PRK05560 796 VSVARVAEEE 805
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
15-818 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1266.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 15 PVKGIVSRSITTEMRESYLDYAMSVITARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDVLGKYHPHGDT 94
Cdd:COG0188 6 PAERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYHPHGDS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 95 SVYDAMVKMAQDFTMRYPLIIGQGNFGSIDGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAANYDNTKTEPTVLPAAI 174
Cdd:COG0188 86 AVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTVLPARF 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 175 PNLLLNGTLGIAVGMATNIPPHNLREVCEATVHLIENPEATTDDLLKFVQGPDFPTGCIAFNQKDMAHAYATGRGPVVVR 254
Cdd:COG0188 166 PNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRGSIRVR 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 255 GDAEIVEGKKGDYQIIITSIPFRVNKSDLLTKVADLVHEKKLEGVRDIRDESTKD-IRVVVELKNNANAQTVLNYLYKHT 333
Cdd:COG0188 246 AKAEIEELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESDRDgMRIVIELKRDANPEVVLNQLYKHT 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 334 QLEETFHYNVVALVDGVPQTLSLKALLEYFILHRKEIVTRRTRFDLAKAQAREHILLGLKKALDHIDEIIKLIKKSKDVD 413
Cdd:COG0188 326 QLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIRASKDPD 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 414 DARQGLMKTFKFSEIQAGAILDMRLQKLAGLERKKVEDELKEVQMLIEELTSLLKSPKKLMDLIKKEIREVIEKYGDDRR 493
Cdd:COG0188 406 EAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELLEIKKKYGDERR 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 494 TKIVKRGATIlSAEDLIADEESVLVLTSGGYIKRTNPAEYRRQRRGGVGVVDLDTKEEDFVTQFLTASAHSDLLFFSDRG 573
Cdd:COG0188 486 TEIEEAEGEI-DIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDFVEHLFVASTHDTLLFFTNKG 564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 574 KVYQLKMYDLPEGKRATKGKSIMNYLSLEGSENITSILAMPKEKkivEGLSLIMTTRDGTVKKSAANKFYEVRRSGLIAI 653
Cdd:COG0188 565 RVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFD---EDKYLLFATKKGTVKKTPLSDFSNIRKNGIIAI 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 654 NLDKGDALISAQFVRKGDSVVLVTTKGLAIRFDEKNVREMGRQAAGVRGMKLRSGDAIVGTGVVPkeaKDAELLVLSSTG 733
Cdd:COG0188 642 NLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTARGVRGIRLKEGDEVVGMAVVD---EEDDLLTVTENG 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 734 YGKKTKLSEYKIQGRGGSGIKTMSITTKTKQLVGGAVLTKGGELVAMSKKSQTIRTGLDEIPTLSRATQGVRVMKMREGD 813
Cdd:COG0188 719 YGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNTQGVRLIRLDEGD 798
|
....*
gi 818893435 814 QVASF 818
Cdd:COG0188 799 KVVSV 803
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
19-817 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1062.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 19 IVSRSITTEMRESYLDYAMSVITARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDVLGKYHPHGDTSVYD 98
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 99 AMVKMAQDFTMRYPLIIGQGNFGSIDGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAANYDNTKTEPTVLPAAIPNLL 178
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 179 LNGTLGIAVGMATNIPPHNLREVCEATVHLIENPEATTDDLLKFVQGPDFPTGCIAFNQKDMAHAYATGRGPVVVRGDAE 258
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 259 IVEGKKGDYQIIITSIPFRVNKSDLLTKVADLVHEKKLEGVRDIRDESTKD-IRVVVELKNNANAQTVLNYLYKHTQLEE 337
Cdd:TIGR01063 241 IEEDSKGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREgIRIVIELKRDAVAEVVLNNLYKQTQLQV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 338 TFHYNVVALVDGVPQTLSLKALLEYFILHRKEIVTRRTRFDLAKAQAREHILLGLKKALDHIDEIIKLIKKSKDVDDARQ 417
Cdd:TIGR01063 321 SFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAKT 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 418 GLMKTFKFSEIQAGAILDMRLQKLAGLERKKVEDELKEVQMLIEELTSLLKSPKKLMDLIKKEIREVIEKYGDDRRTKIV 497
Cdd:TIGR01063 401 RLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPRRTEIV 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 498 KRGATILSAEDLIADEESVLVLTSGGYIKRTNPAEYRRQRRGGVGVVDLDTKEEDFVTQFLTASAHSDLLFFSDRGKVYQ 577
Cdd:TIGR01063 481 YDESEDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVYW 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 578 LKMYDLPEGKRATKGKSIMNYLSLEGSENITSILAMpkeKKIVEGLSLIMTTRDGTVKKSAANKFYEVRRSGLIAINLDK 657
Cdd:TIGR01063 561 LKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSV---KEFDDGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKLDD 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 658 GDALISAQFVRKGDSVVLVTTKGLAIRFDEKNVREMGRQAAGVRGMKLRSGDAIVGTGVVPKEAKdaeLLVLSSTGYGKK 737
Cdd:TIGR01063 638 GDELISVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIKLKNEDFVVSLLVVSEESY---LLIVTENGYGKR 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 738 TKLSEYKIQGRGGSGIKTMSITTKTKQLVGGAVLTKGGELVAMSKKSQTIRTGLDEIPTLSRATQGVRVMKMREGDQVAS 817
Cdd:TIGR01063 715 TSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLIRLDEDDKLVS 794
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
18-754 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 868.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 18 GIVSRSITTEMRESYLDYAMSVITARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDVLGKYHPHGDTSVY 97
Cdd:PRK05561 9 GIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPHGDSSIY 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 98 DAMVKMAQDFTMRYPLIIGQGNFGSIDGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAANYDNTKTEPTVLPAAIPNL 177
Cdd:PRK05561 89 DAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLPARFPNL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 178 LLNGTLGIAVGMATNIPPHNLREVCEATVHLIENPEATTDDLLKFVQGPDFPTG-CIAFNQKDMAHAYATGRGPVVVRGD 256
Cdd:PRK05561 169 LLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDATLEELMEFVPGPDFPTGgEIITGRDGIRKAYETGRGSIRVRAR 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 257 AEIVEGKKGDYQIIITSIPFRVNKSDLLTKVADLVHEKKLEGVRDIRDESTKD--IRVVVELK-NNANAQTVLNYLYKHT 333
Cdd:PRK05561 249 WEIEDLAGGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDREnpVRIVIEPKsNRVDPEALMNHLFATT 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 334 QLEETFHYNVVAL-VDGVPQTLSLKALLEYFILHRKEIVTRRTRFDLAKAQAREHILLGLKKALDHIDEIIKLIKKSkdv 412
Cdd:PRK05561 329 DLESSYRVNMNAIgLDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEVIRIIRES--- 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 413 DDARQGLMKTFKFSEIQAGAILDMRLQKLAGLERKKVEDELKEVQMLIEELTSLLKSPKKLMDLIKKEIREVIEKYGDDR 492
Cdd:PRK05561 406 DEPKANLMARFDLSEIQAEAILELRLRRLAKLEEIEIRKEQDELRKEIAELEAILASERKLRKLIKKELKADAKKFGDPR 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 493 RTKIVKRGATI-LSAEDLIADEESVLVLTSGGYIKRT-----NPAEYRRqrrggvgvvdldtKEEDFVTQFLTASAHSDL 566
Cdd:PRK05561 486 RTPIEEAEEAIaIDEEALIPDEPVTVVLSKKGWVRRAkghsiDASGLSF-------------KEGDSLLFAFEARTTDKL 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 567 LFFSDRGKVYQLKMYDLPEGKRAtkGKSIMNYLSLEGSENITSILAMPKEKKiveglsLIMTTRDGTVKKSAANKFYEVR 646
Cdd:PRK05561 553 LLFTSTGRVYSLPVHELPSARGD--GEPLTGLVDLAPGEEIVHVLAFDPDQK------LLLASSAGYGFVVTLEDLVART 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 647 RSGLIAINLDKGDALISAQFVRKGDSVVLVTTKGLAIRFDEKNVREMGRqAAGVRGMKLRSGDAIVGTGVVpkeAKDAEL 726
Cdd:PRK05561 625 RAGKAVINLKDGDEVLPPVPVEDDDHLAAITSNGRLLVFPLSELPELGK-GKGVKLINLPKDDDGLVDLRV---LNPEDG 700
|
730 740 750
....*....|....*....|....*....|..
gi 818893435 727 LVLSSTGYGKKTK----LSEYKIQgRGGSGIK 754
Cdd:PRK05561 701 LVLLTAGKRKLKLkpseLEKYRGK-RARRGRL 731
|
|
| PRK13979 |
PRK13979 |
DNA topoisomerase IV subunit A; Provisional |
19-712 |
0e+00 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain] Cd Length: 957 Bit Score: 647.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 19 IVSRSITTEMRESYLDYAMSVITARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDVLGKYHPHGDTSVYD 98
Cdd:PRK13979 13 IIKIPLEEAMPENYLPYAVEVAKDRALPDVRDGLKPVHRRILYGAYMLKAFPDKPYYKSARIVGDILGKYHPHGDSSVYD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 99 AMVKMAQDFTMRYPLIIGQGNFGSIDGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAANYDNTKTEPTVLPAAIPNLL 178
Cdd:PRK13979 93 AMVILAQDFTTRMPLIDGHGNWGSIDGDSAAAMRYTEARLTPIAMEMLRDIDKDVVNMVDNYSDSEKEPEVLPARYPNLL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 179 LNGTLGIAVGMATNIPPHNLREVCEATVHLIENPEATTDDLLKFVQGPDFPTGCIAFNQKDMAHAYATGRGPVVVRGDAE 258
Cdd:PRK13979 173 VNGAFGIAVGLATNIPPHNLKEVIDGTLAYIDNNEITTKELMNYIKGPDLPTGGILIGKKSLLSAYETGEGKVTLRAKTK 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 259 IVEGKKGDYQIIITSIPFRVNKSDLLTKV----ADLVHEKKLEGVRDIRDESTKD-IRVVVELKNNAN---AQTVLNYLY 330
Cdd:PRK13979 253 IEKLENGRLGIVITEFPYRRNKAKLLQTIsemtADKKHSKALENISDIRDESDRNgIRAVIEFKKSADedvAEKVLKYLY 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 331 KHTQLEETFHYNVVALVDGVPQTLSLKALLEYFILHRKEIVTRRTRFDLAKAQAREHILLGLKKALDHIDEIIKLIKKSK 410
Cdd:PRK13979 333 KKTDLQCNISFNMVALADGKPETMGLKTMLKHYVEHQKEVVTRRTKKELEIAEKRFHIVEGFIKAIGIMDEIIKTIRSSK 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 411 DVDDARQGLMKTFKFSEIQAGAILDMRLQKLAGLERKKVEDELKEVQMLIEELTSLLKSPKKLMDLIKKEIREVIEKYGD 490
Cdd:PRK13979 413 SKKDASENLIEKFGFTDEQAEAILELMLYRLTGLEIVAFEKEYKELEKLIKKLTKILSSEKELLKVIKKELKEVKEKYGD 492
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 491 DRRTKIVK--RGATIlSAEDLIADEESVLVLTSGGYIKRTNPAEYRRQRRggvGVVDLDTKEEDFVTQFLTASAHSDLLF 568
Cdd:PRK13979 493 ERRTSIIEddEKAKI-DVEELIVVEDVVITLSNEGFIKRIPLKSYNRSNS---NVEDIEYREGDFNKFLIQSNTKDTLLI 568
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 569 FSDRGKVYQLKMYDLPEGKRATKGK---SIMNYLSLEgSENITSILAMpkeKKIVEGLSLIMTTRDGTVKKSAANKFyEV 645
Cdd:PRK13979 569 FTDKGNMYQIKGINIPEFKWKEKGErldEIIKGIDLE-SEKIIEAYSI---EDFTPQKDFIFITDSGGIKKTSLDKF-VT 643
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 646 RRSGLIAINLDKGDALISAQFV---RKGDSVVLVTTKGLAIRFDEKNVREMGRQAAGVRGMKLRSGDAIV 712
Cdd:PRK13979 644 NYTKLMALKLKKGEKLIKVKLVdrtREEKFIKIKTKKGLSFTVEEPELEPVDRNIIGYQLFDLLPNDSIK 713
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
42-484 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 638.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 42 ARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDVLGKYHPHGDTSVYDAMVKMAQDFTMRYPLIIGQGNFG 121
Cdd:cd00187 2 GRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNFG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 122 SIDGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAANYDNTKTEPTVLPAAIPNLLLNGTLGIAVGMATNIPPHNLREV 201
Cdd:cd00187 82 SRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLREV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 202 CEATVHLIENPEATTDDLLKFVQGPDFPTGCIAFNQKDMAHAYATGRGPVVVRGDAEIvEGKKGDYQIIITSIPFRVNKS 281
Cdd:cd00187 162 IDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEI-EDDEGRNTIEITELPYQVNKA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 282 DLLTKVADLVHEKKLEGVRDIRDESTKD-IRVVVELKNNANAQTVLNYLYKHTQLEETFHYNVVALV-DGVPQTLSLKAL 359
Cdd:cd00187 241 KLKEKIAELVKDKKIEGISDVRDESDREgIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDpNGRPKKLNLKEI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 360 LEYFILHRKEIVTRRTRFDLAKAQAREHILLGLKKALDHIDEIIKLIKKSkdvDDARQGLMKTF---KFSEIQAGAILDM 436
Cdd:cd00187 321 LQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEELeklGFSEIQADAILDM 397
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 818893435 437 RLQKLAGLERKKVEDELKEVQMLIEELTSLLKSPKKLMDLIKKEIREV 484
Cdd:cd00187 398 RLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
43-482 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 609.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 43 RALPDVRDGLKPVHRRILYAMQEaGLTVSAKTRKSATVVGDVLGKYHPHGDTSVYDAMVKMAQDFTMRYPLIIGQGNFGS 122
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFE-LLNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 123 -IDGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAANYDNTKTEPTVLPAAIPNLLLNGTLGIAVGMATNIPPHNLREV 201
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 202 CEATVHLIENPEATtdDLLKFVQGPDFPTGCIAFNQKDMAHAYATGRGPVVVRGDAEIVEGKkgdyQIIITSIPFRVNKS 281
Cdd:pfam00521 160 IDALIALLDGPEAT--LLMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIEDRK----TIVITELPYGVWTS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 282 DLLTKVADLVHEKKLEGVRDIRDESTKDIRVVVELKNNANAQTVLNYLYKHTQLEETFHYNVVALVDGVPQTLSLKALLE 361
Cdd:pfam00521 234 DLIEKIEELVKNGKIKGISDIRDESDRGVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKEILK 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 362 YFILHRKEIVTRRTRFDLAKAQAREHILLGLKKALDHIDEIIKLIKKSKDVDDARQGLMKtfKFSEIQAGAILDMRLQKL 441
Cdd:pfam00521 314 EFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIE--ELSEIQADYLLDMRLRRL 391
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 818893435 442 AGLERKKVEDELKEVQMLIEELTSLLKSPKKLMDLIKKEIR 482
Cdd:pfam00521 392 TKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
22-474 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 602.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 22 RSITTEMRESYLDYAMSVITARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDVLGKYHPHGDTSVYDAMV 101
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 102 KMAQDFTMRYPLIIGQGNFGSI-DGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAANYDNTKTEPTVLPAAIPNLLLN 180
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 181 GTLGIAVGMATNIPPHNLREVCEATVHLIENPEATTDDLLKFVQGPDFPTGCIAFnqkdmahayatGRGPVVVRGDAEIV 260
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV-----------GPGKYVVRGKIEIE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 261 EGKkgdyQIIITSIPFRVNKSDLLTKVADLVHEKKLEGVRDIRDES--TKDIRVVVELKNNANAQTVLNYLYKHTQLEET 338
Cdd:smart00434 230 DDN----TIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDEShdRTGVRIVIELKRGAMAEVVLNGLYKLTKLQTT 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 339 FHYNVVALVD-GVPQTLSLKALLEYFILHRKEIVTRRTRFDLAKAQ-AREHILLGLKKALDHIDEIIKLIKKSKD-VDDA 415
Cdd:smart00434 306 FSINMLALFDnGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKDlAKEA 385
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 818893435 416 RQGLMKTFKFSEIQAGAILDMRLQKLAGLERKKVEDELKEVQMLIEELTSLLKSPKKLM 474
Cdd:smart00434 386 KEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
19-761 |
0e+00 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 588.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 19 IVSRSITTEMRESYLDYAMSVITARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDVLGKYHPHGDTSVYD 98
Cdd:TIGR01061 1 IFNKPLEEVFGESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 99 AMVKMAQDFTMRYPLIIGQGNFGSIDGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAANYDNTKTEPTVLPAAIPNLL 178
Cdd:TIGR01061 81 AMVRMSQDWKNNWTLVEMHGNNGSIDGDNAAAMRYTEARLSLIASELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 179 LNGTLGIAVGMATNIPPHNLREVCEATVHLIENPEATTDDLLKFVQGPDFPTGCIAFNQKDMAHAYATGRGPVVVRGDAE 258
Cdd:TIGR01061 161 INGATGIAAGYATNIPPHNLNEVIDALIYRIDHPNCSVDKLMEIVKGPDFPTGGIIQGEDGISKAYETGKGKFIIRAKIE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 259 IVEGKKGDYQIIITSIPFRVNKSDLLTKVADLVHEKKLEGVRDIRDESTKD-IRVVVELKNNANAQTVLNYLYKHTQLEE 337
Cdd:TIGR01061 241 IEVNKNGLNQIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRDESDRNgIRIIIELKKDANAEKILNFLFKHTDLQI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 338 TFHYNVVALVDGVPQTLSLKALLEYFILHRKEIVTRRTRFDLAKAQAREHILLGLKKALDHIDEIIKLIKKSKDVDDARQ 417
Cdd:TIGR01061 321 NYNFNMVAIANRTPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRSSEDKSDAKE 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 418 GLMKTFKFSEIQAGAILDMRLQKLAGLERKKVEDELKEVQMLIEELTSLLKSPKKLMDLIKKEIREVIEKYGDDRRTKIV 497
Cdd:TIGR01061 401 NLIDNFKFTENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLEQIIASEKARNKLLKKQLEEYKKQFAQQRRSQIE 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 498 KRGATI-LSAEDLIADEESVLVLTSGGYIKRTNPAEYRRQRrggvgVVDLDTKEEDFVTQFLTASAHSDLLFFSDRGKVY 576
Cdd:TIGR01061 481 DFINQIkINESELIENEDYYVLITKAGYIKRTSNRSFASSK-----YTDFGSKDDDILFAQTIANTTDQILIFTSLGNII 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 577 QLKMYDLPEGKRATKGKSIMNYLSLEGSENItsILAMPKEKKIVEGLSLIMTTRDGTVKKSAANKFYEVRRS-GLIAINL 655
Cdd:TIGR01061 556 NIPVHKLADIRWKDLGEHLSNKITFDENETI--VFVGTMNEFDVDQPILVLASKLGMVKRIELTELNIKRNSkATLCIKL 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 656 DKGDALISAQFVRKGDSVVLVTTKGLAIRFDEKNVREMGRQAAGVRGMKLRSGDAIVGTGVVPkeaKDAELLVLSSTGYG 735
Cdd:TIGR01061 634 KDKDHLISAFLQQKDKLICLVSDLGYALVFHTNEIPVVGAKAAGVKGMKLKEDDQVKSGVIFE---ANESLVLLTQRGSV 710
|
730 740
....*....|....*....|....*.
gi 818893435 736 KKTKLSEYKIQGRGGSGIKTMSITTK 761
Cdd:TIGR01061 711 KRLSISELVVTSRAATGKKLLPLKKK 736
|
|
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
30-710 |
1.01e-171 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 514.07 E-value: 1.01e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 30 ESYLDYAMSVITARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDVLGKYHPHGDTSVYDAMVKMAQDFTM 109
Cdd:TIGR01062 12 EAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSY 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 110 RYPLIIGQGNFGSIDG-DGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAANYDNTKTEPTVLPAAIPNLLLNGTLGIAVG 188
Cdd:TIGR01062 92 RYPLVDGQGNWGAPDDpKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPNILLNGTTGIAVG 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 189 MATNIPPHNLREVCEATVHLIENPEATTDDLLKFVQGPDFPTGCIAFNQK-DMAHAYATGRGPVVVRGdaeivEGKKGDY 267
Cdd:TIGR01062 172 MATDIPPHNLHELADAALYLIDNPKAGLDDILNIVQGPDFPTEAEIIDKAeEIRKIYETGRGSFRMRA-----RWKKEDG 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 268 QIIITSIPFRVNKSDLLTKVADLVHEKKLEGVRDIRDES--TKDIRVVVELKNNA-NAQTVLNYLYKHTQLEETFHYNV- 343
Cdd:TIGR01062 247 QIVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESdhENPIRVVIVPRSNRvDPDIVMEHLFATTDLEKSYRLNMn 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 344 VALVDGVPQTLSLKALLEYFILHRKEIVTRRTRFDLAKAQAREHILLGLKKALDHIDEIIKLIKKSkdvDDARQGLMKTF 423
Cdd:TIGR01062 327 MIGLDNVPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIREE---DEPKTILMERF 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 424 KFSEIQAGAILDMRLQKLAGLERKKVEDELKEVQMLIEELTSLLKSPKKLMDLIKKEIREVIEKYGDDRRTKIVKRG-AT 502
Cdd:TIGR01062 404 KLSAIQAEAILNLRLRHLAKLEEHAIIDEQSELEKERAILEKILKSERELNQLVKKEIQADATKYGLARRSSLEEREeAK 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 503 ILSAEDLIADEESVLVLTSGGYIkrtnpaeyRRQRRGGVGVVDLDTKEEDFVTQFLTASAHSDLLFFSDRGKVYQLKMYD 582
Cdd:TIGR01062 484 QVSEIDMIPKEPVTIILSKMGWV--------RSAKGHDIDLSTLKYKAGDSEKAIIEGKSNQKVVFIDSTGRSYALDPDN 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 583 LPEGKraTKGKSIMNYLSLEGSENITSILaMPKEKKIveglsLIMTTRDGTVKKSAANKFYEVRRSGLIAINLDKGDALI 662
Cdd:TIGR01062 556 LPSAR--GQGEPLTGKLLLPIGATITNIL-MYSPNQL-----LLMASDAGYGFLCNFNDLIARNKAGKALINLPENASVI 627
|
650 660 670 680
....*....|....*....|....*....|....*....|....*....
gi 818893435 663 SAQFVR-KGDSVVLVTTKGLAIRFDEKNVREMgRQAAGVRGMKLRSGDA 710
Cdd:TIGR01062 628 APLPVNgDSDMIAAITEAGRMLVFPIDDLPEL-SKGKGNKLIRIPSANA 675
|
|
| PRK09631 |
PRK09631 |
DNA topoisomerase IV subunit A; Provisional |
24-496 |
7.56e-66 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain] Cd Length: 635 Bit Score: 231.52 E-value: 7.56e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 24 ITTEMRESYLDYAMSVITARALPDVRDGLKPVHRRILYAMQEAGltvSAKTRKSATVVGDVLgKYHPHGDTSVYDAMVKM 103
Cdd:PRK09631 4 IKTLFKDNFLQYASYVIKDRAIPDVIDGLKPVQRRILHSLFEMH---DGKFHKVANVVGNTM-KYHPHGDASIYEALVNL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 104 A-QDFtmrypLIIGQGNFGSI-DGDGAAAYRYTEAKMARLAGEMLrdIDKDTVEYAANYDNTKTEPTVLPAAIPNLLLNG 181
Cdd:PRK09631 80 AnKDL-----FIDKQGNFGNLfTGDPASAARYIECRLTPLAKEVL--YNKEITEYEPSYDGRNNEPLCLPAKIPVILIQG 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 182 TLGIAVGMATNIPPHNLREVCEATVHLIENPEattddllkFVQGPDFPTGCIAfnqkDmAHAYATGRGPVVVRGDAEIVE 261
Cdd:PRK09631 153 AEGIAVGMATKILPHNFNEILQAVKSELLGES--------FALYPDFPTGGIV----D-VSEYADGNGKVLVRAKIETKD 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 262 GKKgdyqIIITSIPFRVNKSDLLTKVADLVHEKKLEgVRDIRDESTKDIRVVVELKNNANAQTVLNYLYKHTQLEETFHY 341
Cdd:PRK09631 220 EKT----IVIREIPFGTTTESLIASIEKAARKGKIK-ISSINDYTAENVEIEIKLPRGVYASEVIEALYAYTDCEVSISV 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 342 NVVALVDGVPQTLSLKALLEYFILHRKEIVTRRTRFDLAKAQAREHillglKKALDHI---DEIIKLIKKSKDVDDARQG 418
Cdd:PRK09631 295 NLLVIKDRYPVIYTVTDIIKFHAEHLQKVLKMELELERAKLLEKIF-----AKTLEQIfieERIYKRIETISSEEDVISI 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 419 LMKTFK-FSEIQAGAILDMRLQKLAGLERKKV-----EDELKEVQMLIEELTSLLKSPKKLMDLIKKEIREVIEKYGDD- 491
Cdd:PRK09631 370 VLSELKpFKEELSRDVTEEDIENLLKIPIRRIslfdiDKNQKEIRILNKELKSVEKNLKSIKGYAINFIDKLLAKYSKEy 449
|
....*.
gi 818893435 492 -RRTKI 496
Cdd:PRK09631 450 pRKTEI 455
|
|
| PRK12758 |
PRK12758 |
DNA gyrase/topoisomerase IV subunit A; |
32-496 |
1.54e-55 |
|
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain] Cd Length: 869 Bit Score: 206.39 E-value: 1.54e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 32 YLDYAMSVITARALPDVRDGLKPVHRRILYAMQEAGltvSAKTRKSATVVGDVLgKYHPHGDTSVYDAMVKMAQdftmRY 111
Cdd:PRK12758 31 FLDYASYVILERAVPHIEDGLKPVQRRILHSMKEMD---DGRYNKVANVVGHTM-QYHPHGDASIGDALVQLGQ----KD 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 112 PLIIGQGNFGSI-DGDGAAAYRYTEAKMARLAGEMLrdIDKDTVEYAANYDNTKTEPTVLPAAIPNLLLNGTLGIAVGMA 190
Cdd:PRK12758 103 LLIDTQGNWGNIlTGDGAAAPRYIEARLSKFALEVV--FNPKTTEWQLSYDGRKKEPVTLPVKFPLLLAQGAEGIAVGLS 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 191 TNIPPHNLREVCEATVHLIENPEattddllkFVQGPDFPTGCIAfnqkDMAHaYATGR--GPVVVRGDAEIVEGKkgdyQ 268
Cdd:PRK12758 181 TKILPHNFNELIDASIAYLKGKE--------FKLYPDFPTGGII----DVSN-YNDGErgGRVRVRAKIEKLDKK----T 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 269 IIITSIPFRVNKSDLLTKVADLVHEKKLEgVRDIRDESTKDIRVVVELKNNANAQTVLNYLYKHTQLEETFHYNVVALVD 348
Cdd:PRK12758 244 LVITEIPYGTTTSSLIDSILKANDKGKIK-IKKVEDNTAADVEILVHLAPGVSPDKTIDALYAFTDCEVSISPNACVIID 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 349 GVPQTLSLKALLEYFILHRKEIVTRRTRFDLAKAQAREHILlglkkALDHI---DEIIKLIKKSKDVDDA----RQGLmK 421
Cdd:PRK12758 323 NKPHFLGVSDILRRSTDHTVSLLKQELEIRLSELEEQWHFA-----SLEKIfieERIYKEIEEAETWEAVieaiDKGL-E 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 422 TFKFSEIQA------GAILDMRLQKLAGLERKKVEDELKEVQMLIEELTsllkspKKLMDLIKKEI---REVIEKYGDD- 491
Cdd:PRK12758 397 PFKKQFIREvteddiVRLTEIKIKRISKFDSDKADELIARLEAEIAEVK------HHLAHLTDYAIayfTNLKKKYGKGr 470
|
....*.
gi 818893435 492 -RRTKI 496
Cdd:PRK12758 471 eRKTEI 476
|
|
| PRK09630 |
PRK09630 |
DNA topoisomerase IV subunit A; Provisional |
22-510 |
2.41e-43 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022 Cd Length: 479 Bit Score: 164.30 E-value: 2.41e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 22 RSITTEMRESYLDYAMSVITARALPDVRDGLKPVHRRILYAMqeaGLTVSAKTRKSATVVGDVLGkYHPHGDTSVYDAMV 101
Cdd:PRK09630 2 SDVSDLFKTHFMHYASYVILERAIPHILDGLKPVQRRLLWTL---FRMDDGKMHKVANIAGRTMA-LHPHGDAPIVEALV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 102 KMAQdftmRYPLIIGQGNFGS-IDGDGAAAYRYTEAKMARLAGEMLrdIDKDTVEYAANYDNTKTEPTVLPAAIPNLLLN 180
Cdd:PRK09630 78 VLAN----KGYLIDTQGNFGNpLTGDPHAAARYIEARLSPLAKEVL--FNTDLMTFHDSYDGREKEPDILPAKLPLLLLH 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 181 GTLGIAVGMATNIPPHNLREVCEATVHLIENPeattddllKFVQGPDFPTGCIAfnqkdMAHAYATGRGPVVVRGDAEIV 260
Cdd:PRK09630 152 GVDGIAVGMTTKIFPHNFCELLEAQIAILNDQ--------PFTLLPDFPSGGTM-----DASEYQDGLGSITLRASIDII 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 261 EGKkgdyQIIITSIPFRVNKSDLLTKVADLVHEKKLEgVRDIRDESTKDIRVVVELKNNANAQTVLNYLYKHTQLEETFH 340
Cdd:PRK09630 219 NDK----TLLIKEICPSTTTETLIRSIENAAKRGIIK-IDSIQDFSTDLPHIEIKLPKGIYAKDLLRPLFTHTECQVILT 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 341 YNVVALVDGVPQTLSLKALLEyfiLHRK--EIVTRRTRFDLAKAQAREHILLGLK------KALDHIDEIIKLIKKSKDV 412
Cdd:PRK09630 294 SRPTAIYQNKPVETSISEILR---LHTEtlQGYLKKELLILEDSLSREHYHKTLEyifikhKLYDTVREMLSKRKTSPSS 370
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 413 DDARQGLMKTFK-FSEIQAGAILDMRLQKLAGLERKKV-----EDELKEVQMLIEELTSLLKSPKKLMDLIKKEIREVIE 486
Cdd:PRK09630 371 SDLHNAVLEALTpFLDTLPTPVDKQATAQLASLTIKKIlcfneNSYTKELACIEKKQAAVQKDLSQLKKYTVKYLKGLLE 450
|
490 500
....*....|....*....|....*....
gi 818893435 487 KYGD--DRRTKIVK---RGATILSAEDLI 510
Cdd:PRK09630 451 TYGQlgHRKTQIAKfkaKKLSALKQQELF 479
|
|
| 52 |
PHA02592 |
DNA topisomerase II medium subunit; Provisional |
21-479 |
3.37e-40 |
|
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain] Cd Length: 439 Bit Score: 154.06 E-value: 3.37e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 21 SRSITTEMRESYLDYAMSVITARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDV--LGkYHpHGDTSVYD 98
Cdd:PHA02592 5 ERSLKSIVNNEALEYAMYTVEERAIPNLIDGLKPVQRFVIHRALEYAKGNKEKFDKVAAIAGGVadLG-YH-HGETSAQD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 99 AMVKMAQDFTMRYPLIIGQGNFGSIDGDGAAAYRYTEAKMarlaGEMLRDIDKDTvEYAANYDNTKTEPTV--LPaAIPN 176
Cdd:PHA02592 83 AGALMANTWNNNIPLLDGQGNFGSRLVQKAAAARYIFARV----HDNFRKIYKDE-DLAPVHEDPEHIPPAfyLP-IIPM 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 177 LLLNGTLGIAVGMATNIPPHNLREVCEATVHLIeNPEATTDDLLKFvqgPDFpTGCIAfnqkdmahayATGRGPVVVRGD 256
Cdd:PHA02592 157 VLLNGVSGIATGYATNILPHSPKSVIKAVLAAL-NGKDITEPKVQF---PEF-KGEVV----------EIEPGSYEIRGT 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 257 AEIVegkkGDYQIIITSIPFrvnKSDLLTKVADLvheKKLEGVRDI---RDESTKDIRVVVELKNNANAQTVLNYLYKHT 333
Cdd:PHA02592 222 YELN----GKTKLHITEIPV---KYDRETYVAVL---DPLEEKGKIvsyDDCTEDGFRFKVTLKREENEEATHEKIMKDF 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 334 QLEETFHYNVVALV-DGVPQTL-SLKALLEYFILHRKEIVTRRTRFDLAKAQARehillgLKKALDHIdEIIKLIKKSKD 411
Cdd:PHA02592 292 GLIERVSQNITVINeNGKLKVYeNAEDLIRDFVEIRKTYVQKRIQYEIKETEEA------FDLALAKA-EFIKRVIAGEI 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 412 VddaRQGLMKTFKFSEIQAGAILDMRLQKLAGL--------ERKKVEDELKEVQMLIEELTSllKSPKKL----MDLIKK 479
Cdd:PHA02592 365 V---LQGKTRSELTEELSDNKDFGEYADKLVAMniysmtsdEREKLQKEAEELEKEHEYWKK--TTAKKEyikdLEELKK 439
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
41-499 |
6.35e-28 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 121.69 E-value: 6.35e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 41 TARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDVlGKYHpHGDTSVYDAMVKMAQDFT--MRYPLIIGQG 118
Cdd:PTZ00108 678 NERSIPSLVDGLKPGQRKILFACFKRNLKNEIKVAQLSGYVSEH-SAYH-HGEQSLQQTIVGMAQNFVgsNNINLLYPCG 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 119 NFGS--IDGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAaNYDNTKTEPTVLPAAIPNLLLNGTLGIAVGMATNIPPH 196
Cdd:PTZ00108 756 QFGSrlQGGKDHAAARYIFTKLSKITRYIFPEEDDPILDYL-EDDGQSVEPFYYVPIIPMVLVNGAEGIGTGFSTSIPNY 834
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 197 NLREVCEATVHLIENPEATtdDLLKFVQGpdFpTGCIAFNQKdmahayatgrGPVVVRGDAEIVEgkkgDYQIIITSIPF 276
Cdd:PTZ00108 835 NPLDIIDNLRRRLNGEEVR--PLVPWYRG--F-KGTIERNPK----------GKFISKGIYEKVP----DGTVEITELPI 895
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 277 RVNKSDLLTKVADLVHEKKLEgVRDIRDESTK-DIRVVVELKNNANAQTVLNYLYKHTQLEETFHYNVVALVD---GVPQ 352
Cdd:PTZ00108 896 GKWTEDYKEFLESETLKEKDV-IVDYRDYSTAnTVHFTVKLNDGVLEQWEEEGIEKVFKLKSTISTTNMVLFDengKIKK 974
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 353 TLSLKALLEYFILHRKEIVTRRTRFDLAKAQAREHILLGLKKALDH-IDEIIKLIKKSKDV--------------DDARQ 417
Cdd:PTZ00108 975 YSDALDILKEFYLVRLDLYKKRKEYLLGKLERELARLSNKVRFIKHvINGELVITNAKKKDlvkelkklgyvrfkDIIKK 1054
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 418 GLMKTFKFSEIQAGA---------------------ILDMRLQKLAgLER-KKVEDELKEVQMLIEELTSllKSPKklmD 475
Cdd:PTZ00108 1055 KSEKITAEEEEGAEEddeaddeddeeelgaavsydyLLSMPIWSLT-KEKvEKLNAELEKKEKELEKLKN--TTPK---D 1128
|
490 500
....*....|....*....|....
gi 818893435 476 LIKKEIREVIEKYGDDRRTKIVKR 499
Cdd:PTZ00108 1129 MWLEDLDKFEEALEEQEEVEEKEI 1152
|
|
| PLN03128 |
PLN03128 |
DNA topoisomerase 2; Provisional |
42-307 |
6.81e-17 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain] Cd Length: 1135 Bit Score: 85.92 E-value: 6.81e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 42 ARALPDVRDGLKPVHRRILYAMQEAGLTVSAKTRKSATVVGDvLGKYHpHGDTSVYDAMVKMAQDF--TMRYPLIIGQGN 119
Cdd:PLN03128 672 ARSIPSMVDGLKPSQRKVLFACFKRNLKSEIKVAQLSGYVAE-HSAYH-HGEASLASTIIGMAQDFvgSNNINLLTPSGQ 749
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 120 FGS--IDGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAaNYDNTKTEPTVLPAAIPNLLLNGTLGIAVGMATNIPPHN 197
Cdd:PLN03128 750 FGTrlQGGKDAASARYIFTRLSPITRALFPKDDDVLLNYL-NEDGQSIEPEWYCPIIPMVLVNGSEGIGTGWSTFIPNYN 828
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 198 LREVCEATVHLI--ENPEAttddLLKFVQGpdFpTGCIAFNQKDmahayatGRGPVVVRGDAEIVegkkGDYQIIITSIP 275
Cdd:PLN03128 829 PRDIIANIRRLLrgEELEP----MHPWYRG--F-KGTITEVSTS-------RSGSYTVTGIIEQI----GDTTIRITELP 890
|
250 260 270
....*....|....*....|....*....|....
gi 818893435 276 FRVNKSDLL-TKVADLVHEKKLEG-VRDIRDEST 307
Cdd:PLN03128 891 VRKWTQDYKeFLEALLTGTKKKEPeIKDFKENHT 924
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
43-215 |
8.90e-13 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 72.59 E-value: 8.90e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 43 RALPDVRDGLKPVHRRILYAMQEAGLTVSAKTrksATVVGDV--LGKYHpHGDTSVYDAMVKMAQDF--TMRYPLIIGQG 118
Cdd:PLN03237 698 RSIPSMVDGLKPGQRKILFCSFKRNFVKEAKV---AQLSGYVseHSAYH-HGEQSLASTIIGMAQDFvgSNNINLLLPNG 773
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 119 NFG--SIDGDGAAAYRYTEAKMARLAGEMLRDIDKDTVEYAaNYDNTKTEPTVLPAAIPNLLLNGTLGIAVGMATNIPPH 196
Cdd:PLN03237 774 QFGtrLQGGKDHASARYIFTRLSPITRFLFPKDDDILLDYL-NEDGQSIEPTWYMPIIPTVLVNGAEGIGTGWSTFIPNY 852
|
170
....*....|....*....
gi 818893435 197 NLREVCeATVHLIENPEAT 215
Cdd:PLN03237 853 NPRDIV-ANIRRLLNGESM 870
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
671-718 |
1.12e-09 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 54.42 E-value: 1.12e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 818893435 671 DSVVLVTTKGLAIRFDEKNVREMGRQAAGVRGMKLRSGDAIVGTGVVP 718
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
514-561 |
1.52e-07 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 48.25 E-value: 1.52e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 818893435 514 ESVLVLTSGGYIKRTNPAEYRRQRRGGVGVVDLDTKEEDFVTQFLTAS 561
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
776-820 |
3.14e-07 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 47.48 E-value: 3.14e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 818893435 776 ELVAMSKKSQTIRTGLDEIPTLSRATQGVRVMKMREGDQVASFVV 820
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLV 46
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
367-547 |
1.67e-06 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 49.92 E-value: 1.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 367 RKEIVTRRTRFDLAKAqAREHILLGLKKALDHIDEIIKLIKKSKDvddaRQGLMKTFKfsEIQAgaiLDMRLQKLAgLER 446
Cdd:COG1579 37 EDELAALEARLEAAKT-ELEDLEKEIKRLELEIEEVEARIKKYEE----QLGNVRNNK--EYEA---LQKEIESLK-RRI 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818893435 447 KKVEDELKEVQMLIEELTSLLKSPKKLMDLIKKEIREVIEKYgDDRRTKIVKRGATILSA-EDLIADEESVLVltsggyi 525
Cdd:COG1579 106 SDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAEL-DEELAELEAELEELEAErEELAAKIPPELL------- 177
|
170 180
....*....|....*....|....
gi 818893435 526 krtnpAEYRRQR--RGGVGVVDLD 547
Cdd:COG1579 178 -----ALYERIRkrKNGLAVVPVE 196
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
725-780 |
2.39e-06 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 45.17 E-value: 2.39e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 818893435 725 ELLVLSSTGYGKKTKLSEYKIQGRGGSGIKTMSittktkqlvggavLTKGGELVAM 780
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGRGAKGVKGIN-------------LKEGDKVVSV 44
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
565-612 |
1.05e-05 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 43.24 E-value: 1.05e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 818893435 565 DLLFFSDRGKVYQLKMYDLPEGKRATKGKSIMNylsLEGSENITSILA 612
Cdd:pfam03989 2 ELLLITSKGYVKRTPLSEIREQGRGAKGVKGIN---LKEGDKVVSVLV 46
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
625-668 |
5.07e-04 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 38.62 E-value: 5.07e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 818893435 625 LIMTTRDGTVKKSAANKFYEVRR--SGLIAINLDKGDALISAQFVR 668
Cdd:pfam03989 3 LLLITSKGYVKRTPLSEIREQGRgaKGVKGINLKEGDKVVSVLVVN 48
|
|
| |
