NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|818652408|gb|KKS99013|]
View 

hypothetical protein UV74_C0001G0123, partial [Candidatus Woesebacteria bacterium GW2011_GWB1_43_14]

Protein Classification

beta strand repeat-containing protein( domain architecture ID 11460828)

beta strand repeat-containing protein similar to extracellular S-layer proteins and ice nucleation proteins

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 62-579 1.70e-08

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 57.85  E-value: 1.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408   62 LQVDGKAFLGSLNLSTGLYVAGNDIIDSSGRIPGLTVDYFTSLDGSAITNVDAHHLGGKSAQSFLRSDEADEANSAIIFN 141
Cdd:COG3210   787 LDNAGAEISIDITADGTITAAGTTAINVTGSGGTITINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGAN 866

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  142 AVPGSVNVGGGPLYINPGSATAGYTLFGVAVNGSQKFKIDAEGDVFVGSNLNLTGNTLTSDGDLVLDPSGGGVKVGTGTP 221
Cdd:COG3210   867 SGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALS 946

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  222 GSIDLGGDDLYVTGDIETDGTLHGTLNPGFTTGSIPFQGLLGLTQDNLSLYWDDANNRLGIGTNSPNSKLQINTATTSNI 301
Cdd:COG3210   947 GTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTT 1026

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  302 GLILKTTDDITTNNLLQILASNGTVKGFWGADGRLEINLGTDASNLMLGRTAGNATMTGTNNTLIGRNAGNLLTGGVQNI 381
Cdd:COG3210  1027 GTASATGTGTAATAGGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGATGTS 1106

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  382 LIGNYTGNALLTGNSNTAVGYYALVNTTGSNNVAIGQGALQSDTGGSTNIALGGQSVFSNLTGQYNIGIGYQAVYSTTSS 461
Cdd:COG3210  1107 GGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGTLTGLVAVSAVAGGASSASAGDTTAVAAATTTTTGSAINGGAD 1186

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  462 GNIGIGFQSGYGITSGNNNITIGREAGYNTAGGVNNIFIGYQAGYNETGSNKLYIETSNSTSPLIYGEFDNNIVNINGSL 541
Cdd:COG3210  1187 SAATEGTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTASDTGNTTATGGSSAGQTGSFVAAGSASGTGDATTGATAGAVS 1266

                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 818652408  542 GASANLVGYAGSFFNDGNLDTHQGVFIQGCLDTNPTST 579
Cdd:COG3210  1267 NGATSTVAGNAGATATGSTVDIGSTSATSAGGSLDTTG 1304
 
Name Accession Description Interval E-value
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 62-579 1.70e-08

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 57.85  E-value: 1.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408   62 LQVDGKAFLGSLNLSTGLYVAGNDIIDSSGRIPGLTVDYFTSLDGSAITNVDAHHLGGKSAQSFLRSDEADEANSAIIFN 141
Cdd:COG3210   787 LDNAGAEISIDITADGTITAAGTTAINVTGSGGTITINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGAN 866

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  142 AVPGSVNVGGGPLYINPGSATAGYTLFGVAVNGSQKFKIDAEGDVFVGSNLNLTGNTLTSDGDLVLDPSGGGVKVGTGTP 221
Cdd:COG3210   867 SGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALS 946

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  222 GSIDLGGDDLYVTGDIETDGTLHGTLNPGFTTGSIPFQGLLGLTQDNLSLYWDDANNRLGIGTNSPNSKLQINTATTSNI 301
Cdd:COG3210   947 GTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTT 1026

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  302 GLILKTTDDITTNNLLQILASNGTVKGFWGADGRLEINLGTDASNLMLGRTAGNATMTGTNNTLIGRNAGNLLTGGVQNI 381
Cdd:COG3210  1027 GTASATGTGTAATAGGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGATGTS 1106

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  382 LIGNYTGNALLTGNSNTAVGYYALVNTTGSNNVAIGQGALQSDTGGSTNIALGGQSVFSNLTGQYNIGIGYQAVYSTTSS 461
Cdd:COG3210  1107 GGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGTLTGLVAVSAVAGGASSASAGDTTAVAAATTTTTGSAINGGAD 1186

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  462 GNIGIGFQSGYGITSGNNNITIGREAGYNTAGGVNNIFIGYQAGYNETGSNKLYIETSNSTSPLIYGEFDNNIVNINGSL 541
Cdd:COG3210  1187 SAATEGTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTASDTGNTTATGGSSAGQTGSFVAAGSASGTGDATTGATAGAVS 1266

                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 818652408  542 GASANLVGYAGSFFNDGNLDTHQGVFIQGCLDTNPTST 579
Cdd:COG3210  1267 NGATSTVAGNAGATATGSTVDIGSTSATSAGGSLDTTG 1304
LbR_YadA-like cd12820
YadA-like, left-handed beta-roll; This group contains the collagen-binding domain virulence ...
 393-504 1.84e-03

YadA-like, left-handed beta-roll; This group contains the collagen-binding domain virulence factor YadA an adhesion proteins of several Yersinia species, and related cell surface proteins, including Moraxella catarrhalis UspA-like proteins. The collagen-binding portion is found in the hydrophobic N-terminal region. YadA forms a matrix on the bacterial outer membrane, which mediates binding to collagen and epithelial cells. YadA inhibits the complement-activating pathway with the coating of the cell surface with factor H, which impedes C3b molecules. These domains form a left handed beta roll made up of a series of short repeated elements. UspA1 and UspA2 are part of a class of pathogenicity factors that act as cell surface adhesion molecules, in which N-terminal head and neck domains extend from the bacterial outer membrane. The UspA1 head domain of Moraxella catarrhalis, is formed from trimeric left-handed parallel beta-helices of 14-16 amino acid repeats. The UspA1 head domain connects to a neck region of large extended, charged loops that maybe be ligand binding, which is in turn connected to an extended coiled coil domain that tethers the head and neck region to the cell surface via a transmembrane region.


Pssm-ID: 240612 [Multi-domain]  Cd Length: 126  Bit Score: 38.63  E-value: 1.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408 393 TGNSNTAVGYYAlvNTTGSNNVAIGQGalqsdtggstNIALGGQSV----FSNLTGQYNIGIGYQAVYSTTSSgnIGIGF 468
Cdd:cd12820   12 SGENSTAFGYNN--KASGDNSSAFGYG----------NKASGENSSafgyNNKASGENSTAFGYGNKASGENS--SAFGS 77

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 818652408 469 QSgygITSGNNNITIGReagYNTAGGVNNIFIGYQA 504
Cdd:cd12820   78 NN---TASGNNSSAFGY---NNTASGENSTAFGNNS 107
34 PHA02584
long tail fiber, proximal subunit; Provisional
 110-431 2.58e-03

long tail fiber, proximal subunit; Provisional


Pssm-ID: 222890 [Multi-domain]  Cd Length: 1229  Bit Score: 40.89  E-value: 2.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  110 TNVDAHHLGGKSAQSFLRSDEADEANSAIIFNA---VPGSVNVGGGplyINPGSATAGYTLFGVAVNGSQKFKIDAEGdV 186
Cdd:PHA02584  883 TAQNSLKLDGLDSAQFIRRDIDQTVNGSLTFTKntnLSAPLVSSST---ATFGGSVTANSTLTTQNTSNGTVVVVDET-S 958

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  187 FVGSNLNLTGNTLTSDGDLVLDPSGGGVKVGTGTPGSIDLGGDDLYVTGDIETDGTLHGTLNPGFTTGS--IPFQGLLGL 264
Cdd:PHA02584  959 IAFYSQNNTTGNIVFNIDGTVDPINVNANGTLNATGVATNGRAVYAEGGGIARTNNAARAITGGFTIRNdgSTTVFLLTA 1038

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  265 TQDNLSlywddannrlGIGTNSPNSKLQINTATTSNIGLILKTTDDITTNNLLQ-------------ILASNGTVKGFWG 331
Cdd:PHA02584 1039 AGDQTG----------GFNGLKSLIINNANGQVTINDNYIINAGGTIMSGGLTVnsrirsqgtkasyTRAPTADTVGFWS 1108

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  332 ADGRLEINLGT-DASNLMLGRTAGNATMTGTNNTLIGRNAGNLLTGGvqnilIGNYTGNALLTGNSNTAVGyyaLVNTTG 410
Cdd:PHA02584 1109 VDINDSATYNQfPGYFQMVTKTKSPGTLTQFGNTLDSLYQDWSPDGR-----TTRYTRTWQKNKNAWTSFG---EVYTKG 1180

                         330       340
                  ....*....|....*....|.
gi 818652408  411 SNNVAIGQGALQSDTGGSTNI 431
Cdd:PHA02584 1181 NKPTAEDIGAVPADGGTMGNL 1201
 
Name Accession Description Interval E-value
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 62-579 1.70e-08

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 57.85  E-value: 1.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408   62 LQVDGKAFLGSLNLSTGLYVAGNDIIDSSGRIPGLTVDYFTSLDGSAITNVDAHHLGGKSAQSFLRSDEADEANSAIIFN 141
Cdd:COG3210   787 LDNAGAEISIDITADGTITAAGTTAINVTGSGGTITINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGAN 866

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  142 AVPGSVNVGGGPLYINPGSATAGYTLFGVAVNGSQKFKIDAEGDVFVGSNLNLTGNTLTSDGDLVLDPSGGGVKVGTGTP 221
Cdd:COG3210   867 SGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALS 946

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  222 GSIDLGGDDLYVTGDIETDGTLHGTLNPGFTTGSIPFQGLLGLTQDNLSLYWDDANNRLGIGTNSPNSKLQINTATTSNI 301
Cdd:COG3210   947 GTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTT 1026

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  302 GLILKTTDDITTNNLLQILASNGTVKGFWGADGRLEINLGTDASNLMLGRTAGNATMTGTNNTLIGRNAGNLLTGGVQNI 381
Cdd:COG3210  1027 GTASATGTGTAATAGGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGATGTS 1106

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  382 LIGNYTGNALLTGNSNTAVGYYALVNTTGSNNVAIGQGALQSDTGGSTNIALGGQSVFSNLTGQYNIGIGYQAVYSTTSS 461
Cdd:COG3210  1107 GGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGTLTGLVAVSAVAGGASSASAGDTTAVAAATTTTTGSAINGGAD 1186

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  462 GNIGIGFQSGYGITSGNNNITIGREAGYNTAGGVNNIFIGYQAGYNETGSNKLYIETSNSTSPLIYGEFDNNIVNINGSL 541
Cdd:COG3210  1187 SAATEGTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTASDTGNTTATGGSSAGQTGSFVAAGSASGTGDATTGATAGAVS 1266

                         490       500       510
                  ....*....|....*....|....*....|....*...
gi 818652408  542 GASANLVGYAGSFFNDGNLDTHQGVFIQGCLDTNPTST 579
Cdd:COG3210  1267 NGATSTVAGNAGATATGSTVDIGSTSATSAGGSLDTTG 1304
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 49-559 8.86e-08

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 55.54  E-value: 8.86e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408   49 GNLTTEGTVSTGDLQVDGKAFLGSLNLSTGLYVAGNDIIDSSGRIPGLTVDYFTSLDGSAITNVDAHHLGGKSAQSFLRS 128
Cdd:COG3210   206 AGVLANAGGGTAGGVASANSTLTGGVVAAGTGAGVISTGGTDISSLSVAAGAGTGGAGGTGNAGNTTIGTTVTGTNATGS 285

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  129 DEADEANSAIIFNAVPGSVNVGGGPLYINPGSATAGYTLFGVAVNGSQKFKIDAEGDVFVGSNLNLTGNTLTSDGDLVLD 208
Cdd:COG3210   286 NTAGASSGDTTTNGTSSVTGAGGTGVLGGGTAAGITTTNTVGGNGDGNNTTANSGAGLVSGGTGGNNGTTGTGAGSGLTG 365

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  209 PSGGGVKVGTGTPGSIDLGGDDLYVTGDIETDGTLHGTLNPGFTTGSIPFQ--GLLGLTQDNLSLYWDDANNRLGIGTNS 286
Cdd:COG3210   366 TGNGGGLTTAGAGTVASTVGTATASTGNASSTTVLGSGSLATGNTGTTIAGngGSANAGGFTTTGGVLGITGNGTVTGGT 445

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  287 PNSKLQINTATTSNIGLILKTTDDITTNNLLQILASNGTVKGFWGADGRLEINLGTDASNLMLGRTAGNATMTGTNNTLI 366
Cdd:COG3210   446 IGGLTGSGTTNGAGLSGNTDVSGTGTVTNSAGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIATGLTGITAGGGGGG 525

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  367 GRNAGNLLTGGVQNILIGNYTGNALLTGNSNTAVGYYALVNTTGSNNVAIGQGALQSDTGGSTNIALGGQSVFSNLTGQY 446
Cdd:COG3210   526 NATSGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTGTNSGGTVLSIGT 605

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  447 NIGIGYQAVYSTTSSGNIGIGFQSGYGITSGNNNITIGREAGYNTAGGVNNIFIGYQAGYNETGSNKLYIETSNSTSPLI 526
Cdd:COG3210   606 GSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTGTVTSGATGG 685

                         490       500       510
                  ....*....|....*....|....*....|...
gi 818652408  527 YGEFDNNIVNINGSLGASANLVGYAGSFFNDGN 559
Cdd:COG3210   686 TTGTTLNAATGGTLNNAGNTLTISTGSITVTGQ 718
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 57-570 1.40e-07

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 54.77  E-value: 1.40e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408   57 VSTGDLQVDGKAFLGSLNLSTGLYVAGNDIIDSSGRIPGLTVDYFTSLDGSAITNVDahHLGGKSAQSFLRSDEADEANS 136
Cdd:COG3210   805 TAAGTTAINVTGSGGTITINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGG--TAGANSGSLAATAASITVGSG 882

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  137 AIIFNAVPGSVNVGGGPLYINPGSATAGYTLFGVAVNGSQKFKIDAEGDVFVGSNLNLTGNTLTSDGDLVLDPSGGGVKV 216
Cdd:COG3210   883 GVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDG 962

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  217 GTGTPGSIDLGGDDLYVTGDIETDGTLHGTLNPGFTTGSIPFQGLLGLTQDNLSLYWDDANNRLGIGTNSPNSKLQINTA 296
Cdd:COG3210   963 AGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATAGG 1042

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  297 TTSNIGLILKTTDDITTNNLLQILASNGTVKGFWGADGRLEINLGTDASNLMLGRTAGNATMTGTNNTLIGRNAGNLLTG 376
Cdd:COG3210  1043 QNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGATGTSGGTTTSTGGVTASKVG 1122

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  377 GVQNILIGNYTGNALLTGNSNTAVGYYALVNTTGSNNVAIGQGALQSDTGGSTNIALGGQSVFSNLTGQYNIGIGYQAVY 456
Cdd:COG3210  1123 GTTTVGATGTSTASTEAAGAGTLTGLVAVSAVAGGASSASAGDTTAVAAATTTTTGSAINGGADSAATEGTAGTDLKGGD 1202

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  457 STTSSGNIGIGFQSGYGITSGNNNITIGREAGYNTAGGVNNIFIGYQAGYNETGSNKLYIETSNSTSPLIYGEFDNNIVN 536
Cdd:COG3210  1203 STGGSTTTIGTTNVTTTTTLTASDTGNTTATGGSSAGQTGSFVAAGSASGTGDATTGATAGAVSNGATSTVAGNAGATAT 1282

                         490       500       510
                  ....*....|....*....|....*....|....
gi 818652408  537 INGSLGASANLVGYAGSFFNDGNLDTHQGVFIQG 570
Cdd:COG3210  1283 GSTVDIGSTSATSAGGSLDTTGNTAGANGATVGT 1316
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 195-570 9.76e-07

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 52.08  E-value: 9.76e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  195 TGNTLTSDGDLVLDPSGGGVKVGTGTPGSIDLGGDDLYVTGDIETDGTLHGTLNPGFTTGSIPFQGLLGLTQDNLSLYWD 274
Cdd:COG3210   783 AGATLDNAGAEISIDITADGTITAAGTTAINVTGSGGTITINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGT 862

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  275 DANNRLGIGTNSPNSKLQINTATTSNIGLILKTTDDITTNNLLQILASNGTVKGFWGADGRLEINLGTDASNLMLGRTAG 354
Cdd:COG3210   863 AGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGT 942

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  355 NATMTGTNNTLIGRNAGNLLTGGVQNILIGNYTGNALLTGNSNTAVGYYALVNTTGSNNVAIGQGALQSDTGGSTNIALG 434
Cdd:COG3210   943 TALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGV 1022

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  435 GQSVFSNLTGQYNIGIGYQAVYSTTSSGNIGIGFQSGYGITSGNNNITIGREAGYNTAGGVNNIFIGYQAGYNETGSNKL 514
Cdd:COG3210  1023 TGTTGTASATGTGTAATAGGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGA 1102

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 818652408  515 YIETSNSTSPLIYGEFDNNIVNINGSLGASANLVGYAGSFFNDGNLDTHQGVFIQG 570
Cdd:COG3210  1103 TGTSGGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGTLTGLVAVSAVAGGA 1158
AidA COG3468
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
 145-568 1.01e-06

Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442691 [Multi-domain]  Cd Length: 846  Bit Score: 51.87  E-value: 1.01e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408 145 GSVNVGGGPLYINPGSATAGYTLFGVAVNGSQKFKIDAEGDVFVGSNLNLTGNTLTSDGDLVLDPSGGGVKVGTGTPGSI 224
Cdd:COG3468    9 ATGLGGGGTGGGGGLGGTGGGNAGLGIGNGGGGGAASGSGAGGVAGNGGGGGGGAGGGGGGAGSGGGLAGAGSGGTGGNS 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408 225 DLGGDDLYVTGDIETDGTLHGTLNPGFTTGSIPFQGLLGLTQDNLSLYWDDANNRLGIGTNSPNSKLQINTATTSNIGLI 304
Cdd:COG3468   89 TGGGGGNSGTGGTGGGGGGGGSGNGGGGGGGGGGGGTGGGGGGGTGSAGGGGGGGGGGTGVGGTGAAAAGGGTGSGGGGS 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408 305 LKTTDDITTNNLLQILASNGTVKGFWGADGRLEINLGTDASNLMLGRTAGNATMTGTNNTLIGRNAGNLLTGGVQNILIG 384
Cdd:COG3468  169 GGGGGAGGGGGGGAGGSGGAGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGAGGATGGAGSGGNTGGGVGGGGGSAGGT 248

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408 385 NYTGNALLTGNSNTAVGYYALVNTTGSNNVAIGQGALQSDTGGSTNIALGGQSVFSNLTGQYNIGIGYQAVYSTTSSGNI 464
Cdd:COG3468  249 GGGGLTGGGAAGTGGGGGGTGTGSGGGGGGGANGGGSGGGGGASGTGGGGTASTGGGGGGGGGNGGGGGGGSNAGGGSGG 328

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408 465 GIGFQSGYGITSGNNNITIGREAGYNTAGGVNNIFIGYQAGYNETGSNKLYIETSNSTSPLIYGEFDNNIVNINGSLGAS 544
Cdd:COG3468  329 GGGGGGGGGGGGTTLNGAGSAGGGTGAALAGTGGSGSGGGGGGGSGGGGGAGGGGANTGSDGVGTGLTTGGTGNNGGGGV 408

                        410       420
                 ....*....|....*....|....*....
gi 818652408 545 ANLVGYAGSFFND-----GNLDTHQGVFI 568
Cdd:COG3468  409 GGGGGGGLTLTGGtltvnGNYTGNNGTLV 437
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 41-559 2.29e-06

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 50.92  E-value: 2.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408   41 ALLVIDSEGNLTTEGTVSTGDLQVDGKAFLGSLNLSTGLYVAGNDIIDSSGRIPGLTVDYFTSLDGSAITNVDAHHLGGK 120
Cdd:COG3210   274 GTTVTGTNATGSNTAGASSGDTTTNGTSSVTGAGGTGVLGGGTAAGITTTNTVGGNGDGNNTTANSGAGLVSGGTGGNNG 353

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  121 SAQSFLRSDEADEANSAIIFNAVPGSVNVGGGPLYINPGSATAGYTLFGVAVNGSQKFKIDAEGDVFVGSNLNLTGNTLT 200
Cdd:COG3210   354 TTGTGAGSGLTGTGNGGGLTTAGAGTVASTVGTATASTGNASSTTVLGSGSLATGNTGTTIAGNGGSANAGGFTTTGGVL 433

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  201 SDGDLVLDPSGGGVKVGTGTPGSIDLGGDDLYVTGDIETDGTLHGTLNPGFTTGSIPFQGLLGLTQDNLSLYWDDANNRL 280
Cdd:COG3210   434 GITGNGTVTGGTIGGLTGSGTTNGAGLSGNTDVSGTGTVTNSAGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIATG 513

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  281 GIGTNSPNSKLQINTATTSNIGLILKTTDDITTNNLLQILASNGTVKGFWGADGRLEINLGTDASNLMLGRTAGNATMTG 360
Cdd:COG3210   514 LTGITAGGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTG 593

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  361 TNNTLIGRNAGNLLTGGVQNILIGNyTGNALLTGNSNTAVGYYALVNTTGSNNVAIGQGALQSDTGGSTNIALGGQSVFS 440
Cdd:COG3210   594 TNSGGTVLSIGTGSAGATGTITLGA-GTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGG 672

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  441 NLTGQYNIGIGYQAVYSTTSSGNIGIGFQSGYGITSGNNNITIGREAG-YNTAGGVNNIFIGYQAGYNETGSNKLYIETS 519
Cdd:COG3210   673 GTTGTVTSGATGGTTGTTLNAATGGTLNNAGNTLTISTGSITVTGQIGaLANANGDTVTFGNLGTGATLTLNAGVTITSG 752

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|
gi 818652408  520 NSTSPLIYGEFDNNIVNINGSLGASANLVGYAGSFFNDGN 559
Cdd:COG3210   753 NAGTLSIGLTANTTASGTTLTLANANGNTSAGATLDNAGA 792
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 41-570 5.91e-06

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 49.76  E-value: 5.91e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408   41 ALLVIDSEGNLTTEGTVSTGDLQVDGKAFLGSLNLSTGLYVAGNDIIDSSGRIPGLTVDYFTSLDGSAITNVDAHHLGGK 120
Cdd:COG3210   497 ATISNNAGGDANGIATGLTGITAGGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGT 576

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  121 SAQSFLRSDEADEANSAIIFNAVPGSVNVGGGPLYINPGSATAGYTLFGVAVNGSQKFKIDAEGDVFVGSNLNLTGNTLT 200
Cdd:COG3210   577 SNATTAGNSTSATGGTGTNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASA 656

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  201 SDGDLVLDPSGGGVKVGTGTPGSIDLGGDDLYVTGDIETDGTLHGTLNPGFTTGSIPFQGLLGLTQDNLSLYWDDANNRL 280
Cdd:COG3210   657 NGSNTTGVNTAGGTGGGTTGTVTSGATGGTTGTTLNAATGGTLNNAGNTLTISTGSITVTGQIGALANANGDTVTFGNLG 736

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  281 GIGTNSPNSKLQINTATTSNIGLILKTTDDITTNNLLQILASNGTVKGFWGADGRLEINLGTDASNLMLGRTAGNATMTG 360
Cdd:COG3210   737 TGATLTLNAGVTITSGNAGTLSIGLTANTTASGTTLTLANANGNTSAGATLDNAGAEISIDITADGTITAAGTTAINVTG 816

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  361 TNNTLIGRNAGNLLTGGVQNILIGNYTGNALLTGNSNTAVGYYALVNTTGSNNVAIGQGALQSDTGGSTNIALGGQSVFS 440
Cdd:COG3210   817 SGGTITINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTL 896

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  441 NLTGQYNIGIGYQAVYSTTSSGNIGIGFQSGYGITSGNNNITIGREAGYNTAGGVNNIFIGYQAGYNETGSNKLYIETSN 520
Cdd:COG3210   897 TNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSA 976

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|
gi 818652408  521 STSPLIYGEFDNNIVNINGSLGASANLVGYAGSFFNDGNLDTHQGVFIQG 570
Cdd:COG3210   977 VGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTT 1026
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 49-540 1.43e-05

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 48.24  E-value: 1.43e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  49 GNLTTEGTVSTGDLQVDGKAFLGSLNLSTGLYVAGNDIIDSSGRIPGLTVDYFTSLDGSAITNVDAHHLGGKSAQSFLRS 128
Cdd:COG4625    7 GGGGGGGGGGTGGGGAGGGGGAGGGAGGGGAGGGGGGGGGGGGAGGGGGGGGTGGGGGGGGGGGGGGAGGGGGGGGGGGG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408 129 DEADEANSAIIFNAVPGSVNVGGGPLYINPGSATAGYTLFGVAVNGSQKFKIDAEGDVFVGSNLNLTGNTLTSDGDLVLD 208
Cdd:COG4625   87 GGGTGGVGGGGGGGGGGGGGGGGGGGGGGGGSAGGGGGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGGAGGGGGG 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408 209 PSGGGVKVGTGTPGSIDLGGDDLYVTGDIETDGTLHGTLNPGFTTGSIPFQGLLGLTQDNLSLYWDDANNRLGIGTNSPN 288
Cdd:COG4625  167 GGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 246

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408 289 SKLQINTATTSNIGL--ILKTTDDITTNNLLQILASNGTVKGFWGADGRLEINLGTDASNLMLGRTAGNATMTGTNNTLI 366
Cdd:COG4625  247 GAGGGGGGGGGNGGGggAGGGGGGGGGGSGGGGGGGGGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 326

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408 367 GRNAGNLLTGGVQNILIGNYTGNALLTGNSNTAVGYYALVNTTGSNNVAIGQGALQSDTGGSTNIALGGQSVFSNLTGQY 446
Cdd:COG4625  327 GGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGGTGGGGGGGGGGGGGSGGGGAGGGGGSGGGGGGGAGGGGGGGGAG 406

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408 447 NIGIGYQAVYSTTSSGNIGIGFQSGYGITSGNNNITIGREAGYNTAGGVNNIFIGYQA--GYNETGSNKLYIETSNSTSP 524
Cdd:COG4625  407 GTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGGGGGGGGGAGGSGGGAGagGGSGSGAGTLTLTGNNTYTG 486

                        490
                 ....*....|....*.
gi 818652408 525 LIYGEFDNNIVNINGS 540
Cdd:COG4625  487 TTTVNGGGNYTQSAGS 502
LbR_YadA-like cd12820
YadA-like, left-handed beta-roll; This group contains the collagen-binding domain virulence ...
 393-504 1.84e-03

YadA-like, left-handed beta-roll; This group contains the collagen-binding domain virulence factor YadA an adhesion proteins of several Yersinia species, and related cell surface proteins, including Moraxella catarrhalis UspA-like proteins. The collagen-binding portion is found in the hydrophobic N-terminal region. YadA forms a matrix on the bacterial outer membrane, which mediates binding to collagen and epithelial cells. YadA inhibits the complement-activating pathway with the coating of the cell surface with factor H, which impedes C3b molecules. These domains form a left handed beta roll made up of a series of short repeated elements. UspA1 and UspA2 are part of a class of pathogenicity factors that act as cell surface adhesion molecules, in which N-terminal head and neck domains extend from the bacterial outer membrane. The UspA1 head domain of Moraxella catarrhalis, is formed from trimeric left-handed parallel beta-helices of 14-16 amino acid repeats. The UspA1 head domain connects to a neck region of large extended, charged loops that maybe be ligand binding, which is in turn connected to an extended coiled coil domain that tethers the head and neck region to the cell surface via a transmembrane region.


Pssm-ID: 240612 [Multi-domain]  Cd Length: 126  Bit Score: 38.63  E-value: 1.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408 393 TGNSNTAVGYYAlvNTTGSNNVAIGQGalqsdtggstNIALGGQSV----FSNLTGQYNIGIGYQAVYSTTSSgnIGIGF 468
Cdd:cd12820   12 SGENSTAFGYNN--KASGDNSSAFGYG----------NKASGENSSafgyNNKASGENSTAFGYGNKASGENS--SAFGS 77

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 818652408 469 QSgygITSGNNNITIGReagYNTAGGVNNIFIGYQA 504
Cdd:cd12820   78 NN---TASGNNSSAFGY---NNTASGENSTAFGNNS 107
34 PHA02584
long tail fiber, proximal subunit; Provisional
 110-431 2.58e-03

long tail fiber, proximal subunit; Provisional


Pssm-ID: 222890 [Multi-domain]  Cd Length: 1229  Bit Score: 40.89  E-value: 2.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  110 TNVDAHHLGGKSAQSFLRSDEADEANSAIIFNA---VPGSVNVGGGplyINPGSATAGYTLFGVAVNGSQKFKIDAEGdV 186
Cdd:PHA02584  883 TAQNSLKLDGLDSAQFIRRDIDQTVNGSLTFTKntnLSAPLVSSST---ATFGGSVTANSTLTTQNTSNGTVVVVDET-S 958

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  187 FVGSNLNLTGNTLTSDGDLVLDPSGGGVKVGTGTPGSIDLGGDDLYVTGDIETDGTLHGTLNPGFTTGS--IPFQGLLGL 264
Cdd:PHA02584  959 IAFYSQNNTTGNIVFNIDGTVDPINVNANGTLNATGVATNGRAVYAEGGGIARTNNAARAITGGFTIRNdgSTTVFLLTA 1038

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  265 TQDNLSlywddannrlGIGTNSPNSKLQINTATTSNIGLILKTTDDITTNNLLQ-------------ILASNGTVKGFWG 331
Cdd:PHA02584 1039 AGDQTG----------GFNGLKSLIINNANGQVTINDNYIINAGGTIMSGGLTVnsrirsqgtkasyTRAPTADTVGFWS 1108

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818652408  332 ADGRLEINLGT-DASNLMLGRTAGNATMTGTNNTLIGRNAGNLLTGGvqnilIGNYTGNALLTGNSNTAVGyyaLVNTTG 410
Cdd:PHA02584 1109 VDINDSATYNQfPGYFQMVTKTKSPGTLTQFGNTLDSLYQDWSPDGR-----TTRYTRTWQKNKNAWTSFG---EVYTKG 1180

                         330       340
                  ....*....|....*....|.
gi 818652408  411 SNNVAIGQGALQSDTGGSTNI 431
Cdd:PHA02584 1181 NKPTAEDIGAVPADGGTMGNL 1201
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH