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Conserved domains on  [gi|818621560|gb|KKS69766|]
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polymerase III, subunit gamma and tau protein [Candidatus Azambacteria bacterium GW2011_GWA2_42_62]

Protein Classification

DnaX/STICHEL family protein( domain architecture ID 11494202)

DnaX/STICHEL family protein similar to Arabidopsis thaliana STICHEL that acts as a key regulator of trichome branching through an endoreduplication-independent pathway and to bacterial DNA polymerase III subunit gamma/tau

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
5-340 7.33e-150

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


:

Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 425.83  E-value: 7.33e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560    5 VLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN------------------ 66
Cdd:TIGR02397   3 VLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNgpdgepcnecesckeins 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   67 ---LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPA 143
Cdd:TIGR02397  83 gssLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKIPA 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  144 TIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEELLGAI 223
Cdd:TIGR02397 163 TILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLGLV 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  224 DFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKVDSSLVDLMSQEltvdQVEIVKKQAESF 303
Cdd:TIGR02397 243 DDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTPSNLLAVLES----EQEFLKELALKL 318
                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 818621560  304 SLNNVAQAIKIFTNARNDIKRSPIPSLPIELAVVEII 340
Cdd:TIGR02397 319 SLEFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
 
Name Accession Description Interval E-value
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
5-340 7.33e-150

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 425.83  E-value: 7.33e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560    5 VLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN------------------ 66
Cdd:TIGR02397   3 VLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNgpdgepcnecesckeins 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   67 ---LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPA 143
Cdd:TIGR02397  83 gssLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKIPA 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  144 TIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEELLGAI 223
Cdd:TIGR02397 163 TILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLGLV 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  224 DFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKVDSSLVDLMSQEltvdQVEIVKKQAESF 303
Cdd:TIGR02397 243 DDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTPSNLLAVLES----EQEFLKELALKL 318
                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 818621560  304 SLNNVAQAIKIFTNARNDIKRSPIPSLPIELAVVEII 340
Cdd:TIGR02397 319 SLEFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
1-340 7.92e-142

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 412.73  E-value: 7.92e-142
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGC---------------- 64
Cdd:PRK05563   1 MMYQALYRKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNClnppdgepcneceick 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  65 -----SNLDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAH 139
Cdd:PRK05563  81 aitngSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 140 KVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEEL 219
Cdd:PRK05563 161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 220 LGAIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKVDSSLVDLmsqELTVDQVEIVKKQ 299
Cdd:PRK05563 241 TGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRDLLLVKTSPELEIL---DESTENDELFKEL 317
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 818621560 300 AESFSLNNVAQAIKIFTNARNDIKRSPIPSLPIELAVVEII 340
Cdd:PRK05563 318 SEKLDIERLYRMIDILNDAQQQIKWTNQPRIYLEVALVKLC 358
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
12-340 1.06e-135

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 389.17  E-value: 1.06e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  12 PQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN---------------------LDLL 70
Cdd:COG2812    6 PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENgptgepcgecescraiaagshPDVI 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  71 EIDA-ASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRV 149
Cdd:COG2812   86 EIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRC 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 150 QQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQlriwnenmitkediEELLGAIDF-EKV 228
Cdd:COG2812  166 QRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQ--------------AIAFGLLDRrELL 231
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 229 RVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKVDSSLVDLMSQeltvDQVEIVKKQAESFSLNNV 308
Cdd:COG2812  232 LDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAELLVNE----DERERLQELARRLSPERL 307
                        330       340       350
                 ....*....|....*....|....*....|..
gi 818621560 309 AQAIKIFTNARNDIKRSPIPSLPIELAVVEII 340
Cdd:COG2812  308 LRAIQILLEARRELERNVNPRLALEMLLLRLA 339
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
20-158 3.72e-42

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 143.89  E-value: 3.72e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   20 GQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSNL---------------------DLLEIDAASNR 78
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPgddlpcgqcrscrriesgnhpDLVIIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   79 -GIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQQFTFKKL 157
Cdd:pfam13177  81 iKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPL 160

                  .
gi 818621560  158 A 158
Cdd:pfam13177 161 S 161
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
19-136 3.59e-17

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 77.57  E-value: 3.59e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  19 IGQEHIVRTLTNALKLGRVNHaYLFSGPRGTGKTTIARLLAKSVGCSNLDLLEIDAASNRGIDEIR-----QLRDGIKFA 93
Cdd:cd00009    1 VGQEEAIEALREALELPPPKN-LLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAelfghFLVRLLFEL 79
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 818621560  94 PTAGKYKVFIIDEAHQLTKEAFNALLKTLEE------PPAHAIFILATT 136
Cdd:cd00009   80 AEKAKPGVLFIDEIDSLSRGAQNALLRVLETlndlriDRENVRVIGATN 128
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
38-133 1.07e-06

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 47.75  E-value: 1.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560    38 NHAYLFSGPRGTGKTTIARLLAKSVGCSNLDLLEIDAASNRGIDEIRQLRDGIKFAPTAG----------------KYKV 101
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGsgelrlrlalalarklKPDV 81
                           90       100       110
                   ....*....|....*....|....*....|..
gi 818621560   102 FIIDEAHQLTKEAFNALLKTLEEPPAHAIFIL 133
Cdd:smart00382  82 LILDEITSLLDAEQEALLLLLEELRLLLLLKS 113
 
Name Accession Description Interval E-value
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
5-340 7.33e-150

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 425.83  E-value: 7.33e-150
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560    5 VLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN------------------ 66
Cdd:TIGR02397   3 VLARKYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHAYLFSGPRGTGKTSIARIFAKALNCQNgpdgepcnecesckeins 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   67 ---LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPA 143
Cdd:TIGR02397  83 gssLDVIEIDAASNNGVDDIREILDNVKYAPSSGKYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKIPA 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  144 TIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEELLGAI 223
Cdd:TIGR02397 163 TILSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNGKITYEDVNELLGLV 242
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  224 DFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKVDSSLVDLMSQEltvdQVEIVKKQAESF 303
Cdd:TIGR02397 243 DDEKLIELLEAILNKDTAEALKILDEILESGVDPEKFLEDLIEILRDLLLIKKTPSNLLAVLES----EQEFLKELALKL 318
                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 818621560  304 SLNNVAQAIKIFTNARNDIKRSPIPSLPIELAVVEII 340
Cdd:TIGR02397 319 SLEFLLRLLDILLEALKDLRFSNDPRIWLEMTLLRLL 355
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
1-340 7.92e-142

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 412.73  E-value: 7.92e-142
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGC---------------- 64
Cdd:PRK05563   1 MMYQALYRKWRPQTFEDVVGQEHITKTLKNAIKQGKISHAYLFSGPRGTGKTSAAKIFAKAVNClnppdgepcneceick 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  65 -----SNLDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAH 139
Cdd:PRK05563  81 aitngSLMDVIEIDAASNNGVDEIRDIRDKVKYAPSEAKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 140 KVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEEL 219
Cdd:PRK05563 161 KIPATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDGKVTYEDALEV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 220 LGAIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKVDSSLVDLmsqELTVDQVEIVKKQ 299
Cdd:PRK05563 241 TGSVSQEALDDLVDAIVEGDVAKALKILEELLDEGKDPNRFIEDLIYYLRDLLLVKTSPELEIL---DESTENDELFKEL 317
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 818621560 300 AESFSLNNVAQAIKIFTNARNDIKRSPIPSLPIELAVVEII 340
Cdd:PRK05563 318 SEKLDIERLYRMIDILNDAQQQIKWTNQPRIYLEVALVKLC 358
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
12-340 1.06e-135

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 389.17  E-value: 1.06e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  12 PQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN---------------------LDLL 70
Cdd:COG2812    6 PQTFDDVVGQEHVVRTLKNALASGRLAHAYLFTGPRGVGKTTLARILAKALNCENgptgepcgecescraiaagshPDVI 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  71 EIDA-ASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRV 149
Cdd:COG2812   86 EIDAeASNIGVDDIRELIEKVSYAPVEGRYKVYIIDEAHMLTTEAFNALLKTLEEPPPHVVFILATTEPQKLLPTILSRC 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 150 QQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQlriwnenmitkediEELLGAIDF-EKV 228
Cdd:COG2812  166 QRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLLDQ--------------AIAFGLLDRrELL 231
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 229 RVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKVDSSLVDLMSQeltvDQVEIVKKQAESFSLNNV 308
Cdd:COG2812  232 LDLLEALLAGDVAALLALAEELAKRGRDLKRFLDDLLSLLRDLLLLKLGPDAELLVNE----DERERLQELARRLSPERL 307
                        330       340       350
                 ....*....|....*....|....*....|..
gi 818621560 309 AQAIKIFTNARNDIKRSPIPSLPIELAVVEII 340
Cdd:COG2812  308 LRAIQILLEARRELERNVNPRLALEMLLLRLA 339
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
1-338 1.18e-120

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 359.89  E-value: 1.18e-120
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN-------------- 66
Cdd:PRK14950   1 MTVQVLYRKWRSQTFAELVGQEHVVQTLRNAIAEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTTndpkgrpcgtcemc 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  67 --------LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEA 138
Cdd:PRK14950  81 raiaegsaVDVIEMDAASHTSVDDAREIIERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEV 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 139 HKVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEE 218
Cdd:PRK14950 161 HKVPATILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYGGEISLSQVQS 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 219 LLGAIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKV--DSSLVDlmsqeLTVDQVEIV 296
Cdd:PRK14950 241 LLGISGDEEVKALAEALLAKDLKAALRTLNAVAADGADLRQFTRDLVEYLRQVMLLNSgaDRSLLD-----LTADEKAAL 315
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 818621560 297 KKQAESFSLNNVAQAIKIFTNARNDIKRSPIPSLPIELAVVE 338
Cdd:PRK14950 316 QKVSQIANLEALTKWVKAFSQLDFQLRTTSYGQLPLELAVIE 357
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
1-338 3.22e-117

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 350.58  E-value: 3.22e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGC---------------- 64
Cdd:PRK14965   1 MSYLVLARKYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHAFLFTGARGVGKTSTARILAKALNCeqgltaepcnvcppcv 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  65 -----SNLDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAH 139
Cdd:PRK14965  81 eitegRSVDVFEIDGASNTGVDDIRELRENVKYLPSRSRYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 140 KVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEEL 219
Cdd:PRK14965 161 KVPITILSRCQRFDFRRIPLQKIVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLDQVLAFCGDAVGDDDVAEL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 220 LGAIDfekVRVLSDHLQ---DSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKVDSSLVDLMsqELTVDQVEIV 296
Cdd:PRK14965 241 LGVVD---RRLLLDISAavfGRDTRALLEIVERVDEFGYNMRQFCQELIDHLRNLVVLRAVGEPGDLL--DLSEAELAEL 315
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 818621560 297 KKQAESFSLNNVAQAIKIFTNARNDIKRSPIPSLPIELAVVE 338
Cdd:PRK14965 316 RAQAAAADAADLQRHLTLLLRAEGEMAHASFPRLVLEMALLK 357
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
8-337 5.47e-110

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 329.09  E-value: 5.47e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   8 RKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSNL-------------------- 67
Cdd:PRK14953   8 RKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPqegepcgkcencveidkgsf 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  68 -DLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIV 146
Cdd:PRK14953  88 pDLIEIDAASNRGIDDIRALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYDKIPPTIL 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 147 SRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEELLGAIDFE 226
Cdd:PRK14953 168 SRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEGKVTIKVVEEFLGIVSQE 247
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 227 KVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKVdsslvdlMSQELTVDQVEIVKKQAEsFSLN 306
Cdd:PRK14953 248 SVRKFLNLLLESDVDEAIKFLRTLEEKGYNLNKFWKQLEEEIRNILLNKS-------LKNPEEVFQVEDFYRKLE-KPLE 319
                        330       340       350
                 ....*....|....*....|....*....|.
gi 818621560 307 NVAQAIKIFTNARNDiKRSPIPSLPIELAVV 337
Cdd:PRK14953 320 ALLYLEDVINKAFSE-ARTRDPLRAYELAIL 349
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
1-343 1.44e-103

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 319.84  E-value: 1.44e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCS--------------- 65
Cdd:PRK07133   3 MKYKALYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHAYLFSGPRGTGKTSVAKIFANALNCShktdllepcqecien 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  66 ---NLDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVP 142
Cdd:PRK07133  83 vnnSLDIIEMDAASNNGVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEVHKIP 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 143 ATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEELLGA 222
Cdd:PRK07133 163 LTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVSIFGNNKITLKNVEELFGL 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 223 IDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKV--DSSLVDLMSQElTVDQVEIVKKQA 300
Cdd:PRK07133 243 VSNENLINLLNLLYSKDIKEVLNILNQIKEQGIDPELLLISLINLVKEFIIFNKtkDNSLLEYYSEE-DLEKLKIDDDFA 321
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|...
gi 818621560 301 ESFslnnvaqaIKIFTNARNDIKRSPIPSLPIELAVVEIINNK 343
Cdd:PRK07133 322 YKF--------IEILFDLLKDLKISDNPNDTLEILIIKLLALS 356
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
5-278 8.30e-95

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 289.74  E-value: 8.30e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   5 VLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN------------------ 66
Cdd:PRK14962   3 ALYRKYRPKTFSEVVGQDHVKKLIINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENrkgvepcnecracrside 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  67 ---LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPA 143
Cdd:PRK14962  83 gtfMDVIELDAASNRGIDEIRKIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPP 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 144 TIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEELLGAI 223
Cdd:PRK14962 163 TIISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEGKITLETVHEALGLI 242
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 818621560 224 DFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVfakaFINHLRKIMLIKVDS 278
Cdd:PRK14962 243 PIEVVRDYINAIFNGDVKRVFTVLDDVYYSGKDYEV----LIQQAIEDLVEDLER 293
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
1-312 2.74e-94

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 293.00  E-value: 2.74e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGC---------------- 64
Cdd:PRK14954   1 MSYQVIARKYRPSKFADITAQEHITHTIQNSLRMDRVGHGYIFSGLRGVGKTTAARVFAKAVNCqrmiddpvylqevtep 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  65 -------------SNLDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIF 131
Cdd:PRK14954  81 cgecescrdfdagTSLNISEFDAASNNSVDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 132 ILATTEAHKVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWN---- 207
Cdd:PRK14954 161 IFATTELHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILDQVIAFSvgse 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 208 -ENMITKEDIEELLGAIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIkvdsslVDLMSQ 286
Cdd:PRK14954 241 aEKVIAYQGVAELLNYIDDEQFFDVTDAIAENDAVKMLEVARFVIDNGYDEQDFLEKLIEHFRNFLVL------YNLRST 314
                        330       340
                 ....*....|....*....|....*.
gi 818621560 287 ELtVDQVEIVKKQAESFSLNNVAQAI 312
Cdd:PRK14954 315 RL-IERPESVKERYQQSAGGLTPAAV 339
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
5-280 2.95e-94

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 287.82  E-value: 2.95e-94
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   5 VLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGC-------------------- 64
Cdd:PRK06305   6 VSSRKYRPQTFSEILGQDAVVAVLKNALRFNRAAHAYLFSGIRGTGKTTLARIFAKALNCqnptedqepcnqcasckeis 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  65 --SNLDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVP 142
Cdd:PRK06305  86 sgTSLDVLEIDGASHRGIEDIRQINETVLFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIHKIP 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 143 ATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEELLGA 222
Cdd:PRK06305 166 GTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFPKSLDPDSVAKALGL 245
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 818621560 223 IDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKVDSSL 280
Cdd:PRK06305 246 LSQDSLYTLDEAITTQNYAQALEPVTDAMNSGVAPAHFLHDLTLFFRNILLKQYNKQL 303
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
1-326 1.73e-93

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 288.18  E-value: 1.73e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN-------------- 66
Cdd:PRK14969   1 MSYQVLARKWRPKSFSELVGQEHVVRALTNALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETgvtatpcgvcsacl 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  67 -------LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAH 139
Cdd:PRK14969  81 eidsgrfVDLIEVDAASNTQVDAMRELLDNAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 140 KVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEEL 219
Cdd:PRK14969 161 KIPVTVLSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAYGGGTVNESEVRAM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 220 LGAIDFEKVRVLSDHL--QDSNAkgaidyigkLIEAGVDLEVFAKAFinhlrkimlikvDSSLVDLMS--QELTVDQV-- 293
Cdd:PRK14969 241 LGAIDQDYLFALLEALlaQDGAA---------LLAIADAMEERSLSF------------DAALQDLAAllHRLAIAQTvp 299
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|...
gi 818621560 294 -EIVKKQAESFSLNNVAQAI---------KIFTNARNDIKRSP 326
Cdd:PRK14969 300 dSIADDLPERDRLLDLAKRLspediqlyyQIALHGRRDLGLAP 342
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
1-340 3.60e-93

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 283.32  E-value: 3.60e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCS--------------- 65
Cdd:PRK14955   1 MSYQVIARKYRPKKFADITAQEHITRTIQNSLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQrmiddadylqevtep 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  66 --------------NLDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIF 131
Cdd:PRK14955  81 cgecescrdfdagtSLNISEFDAASNNSVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 132 ILATTEAHKVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWN---- 207
Cdd:PRK14955 161 IFATTELHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILDQVIAFSvese 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 208 -ENMITKEDIEELLGAIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKvdsslvDLMSQ 286
Cdd:PRK14955 241 gEGSIRYDKVAELLNYIDDEHFFAVTDAVADGDAVAMLDVAQFVIRNGYDEQDFLEKLIEHLRNFLVVH------NLRST 314
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 818621560 287 ELtVDQVEIVKKQ----AESFSLNNVAQAIKIFTNARNDIKRSPIPSLPIELAVVEII 340
Cdd:PRK14955 315 RL-VERPDAVRERyerdAAKFSPEVIMQMTDLLLQTQKELKFQFEYQFRFELALLKLI 371
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
6-254 1.17e-91

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 286.09  E-value: 1.17e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   6 LYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN------------------- 66
Cdd:PRK14948   6 LHHKYRPQRFDELVGQEAIATTLKNALISNRIAPAYLFTGPRGTGKTSSARILAKSLNCLNsdkptpepcgkcelcraia 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  67 ----LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVP 142
Cdd:PRK14948  86 agnaLDVIEIDAASNTGVDNIRELIERAQFAPVQARWKVYVIDECHMLSTAAFNALLKTLEEPPPRVVFVLATTDPQRVL 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 143 ATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWnENMITKEDIEELLGA 222
Cdd:PRK14948 166 PTIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIEPEALTLVAQRSQGGLRDAESLLDQLSLL-PGPITPEAVWDLLGA 244
                        250       260       270
                 ....*....|....*....|....*....|..
gi 818621560 223 IDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAG 254
Cdd:PRK14948 245 VPEQDLLNLLKALASNDPESLLDSCRQLLDRG 276
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
6-254 1.45e-90

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 279.80  E-value: 1.45e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   6 LYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGC--------------------S 65
Cdd:PRK14963   4 LYQRARPITFDEVVGQEHVKEVLLAALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNCsgedpkpcgecesclavrrgA 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  66 NLDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATI 145
Cdd:PRK14963  84 HPDVLEIDAASNNSVEDVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPPTI 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 146 VSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLrIWNENMITKEDIEELLGAIDF 225
Cdd:PRK14963 164 LSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLERL-LALGTPVTRKQVEEALGLPPQ 242
                        250       260
                 ....*....|....*....|....*....
gi 818621560 226 EKVRVLSDHLQDSNAKGAIDYIGKLIEAG 254
Cdd:PRK14963 243 ERLRGIAAALAQGDAAEALSGAAQLYRDG 271
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
1-256 2.31e-89

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 280.60  E-value: 2.31e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSV----G--------CSN-- 66
Cdd:PRK07994   1 MSYQVLARKWRPQTFAEVVGQEHVLTALANALDLGRLHHAYLFSGTRGVGKTTIARLLAKGLncetGitatpcgeCDNcr 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  67 -------LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAH 139
Cdd:PRK07994  81 eieqgrfVDLIEIDAASRTKVEDTRELLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 140 KVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEEL 219
Cdd:PRK07994 161 KLPVTILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGNGQVTTDDVSAM 240
                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 818621560 220 LGAIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVD 256
Cdd:PRK07994 241 LGTLDDDQALSLLEALVEGDGERVMALINQLAERGPD 277
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
1-341 6.18e-88

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 276.27  E-value: 6.18e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGN-LVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSNL------------ 67
Cdd:PRK14971   1 MENyIVSARKYRPSTFESVVGQEALTTTLKNAIATNKLAHAYLFCGPRGVGKTTCARIFAKTINCQNLtadgeacneces 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  68 ----------DLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTE 137
Cdd:PRK14971  81 cvafneqrsyNIHELDAASNNSVDDIRNLIEQVRIPPQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 138 AHKVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIE 217
Cdd:PRK14971 161 KHKILPTILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTGGNITYKSVI 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 218 ELLGAIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKvDSSLVDLMSQELTVDQ--VEI 295
Cdd:PRK14971 241 ENLNILDYDYYFRLTDALLAGKVSDSLLLFDEILNKGFDGSHFITGLASHFRDLLVCK-DAATLQLLEVGESIRQryLEQ 319
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 818621560 296 VKKQAESFSLnnvaQAIKI-------FTNARNdiKRspipsLPIELAVVEIIN 341
Cdd:PRK14971 320 AQKCPMSFLY----RALKLcnqcdlnYRASKN--KR-----LLVELTLIQLAQ 361
PRK09111 PRK09111
DNA polymerase III subunits gamma and tau; Validated
5-259 3.64e-87

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236382 [Multi-domain]  Cd Length: 598  Bit Score: 273.70  E-value: 3.64e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   5 VLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCS------------------- 65
Cdd:PRK09111  13 VLARKYRPQTFDDLIGQEAMVRTLTNAFETGRIAQAFMLTGVRGVGKTTTARILARALNYEgpdgdggptidlcgvgehc 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  66 -------NLDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEA 138
Cdd:PRK09111  93 qaimegrHVDVLEMDAASHTGVDDIREIIESVRYRPVSARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHVKFIFATTEI 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 139 HKVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEE 218
Cdd:PRK09111 173 RKVPVTVLSRCQRFDLRRIEADVLAAHLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLDQAIAHGAGEVTAEAVRD 252
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 818621560 219 LLGAIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEV 259
Cdd:PRK09111 253 MLGLADRARVIDLFEALMRGDVAAALAEFRAQYDAGADPVV 293
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
1-326 9.55e-87

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 275.43  E-value: 9.55e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN-------------- 66
Cdd:PRK08691   1 MAYQVLARKWRPKTFADLVGQEHVVKALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSLNCENaqhgepcgvcqsct 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  67 -------LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAH 139
Cdd:PRK08691  81 qidagryVDLLEIDAASNTGIDNIREVLENAQYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 140 KVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEEL 219
Cdd:PRK08691 161 KVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALGSGKVAENDVRQM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 220 LGAIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVdlevfakAFINHLRKIMLIKVDSSLVDLMSQELTVDQVE--IVK 297
Cdd:PRK08691 241 IGAVDKQYLYELLTGIINQDGAALLAKAQEMAACAV-------GFDNALGELAILLQQLALIQAVPSALAHDDPDsdILH 313
                        330       340
                 ....*....|....*....|....*....
gi 818621560 298 KQAESFSLNNVAQAIKIFTNARNDIKRSP 326
Cdd:PRK08691 314 RLAQTISGEQIQLYYQIAVHGKRDLSLAP 342
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
9-339 1.62e-86

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 271.26  E-value: 1.62e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   9 KYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGC---------------------SNL 67
Cdd:PRK06647   9 KRRPRDFNSLEGQDFVVETLKHSIESNKIANAYIFSGPRGVGKTSSARAFARCLNCvngptpmpcgecsscksidndNSL 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  68 DLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVS 147
Cdd:PRK06647  89 DVIEIDGASNTSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKLPATIKS 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 148 RVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEELLGAIDFEK 227
Cdd:PRK06647 169 RCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSDSDITLEQIRSKMGLTGDEF 248
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 228 VRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKVDSSLVDLMSQELtvdqvEIVKKQAESFSLNN 307
Cdd:PRK06647 249 LEKLASSILNEDAKELLCVLDSVFLSGVSVEQFLLDCIEFFRELLFLKHGIKNEAFIGIKA-----ERLPEKLREFDLSQ 323
                        330       340       350
                 ....*....|....*....|....*....|..
gi 818621560 308 VAQAIKIFTNARNDIKRSPIPSLPIELAVVEI 339
Cdd:PRK06647 324 IERAISVLLETYRDLQFSVNPRYELEINFSKI 355
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
1-244 1.65e-86

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 274.83  E-value: 1.65e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN-------------- 66
Cdd:PRK12323   1 MSYQVLARKWRPRDFTTLVGQEHVVRALTHALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLNCTGadgeggitaqpcgq 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  67 ------------LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILA 134
Cdd:PRK12323  81 cracteidagrfVDYIEMDAASNRGVDEMAQLLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 135 TTEAHKVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKE 214
Cdd:PRK12323 161 TTDPQKIPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTDQAIAYSAGNVSEE 240
                        250       260       270
                 ....*....|....*....|....*....|.
gi 818621560 215 DIEELLGAIDFEK-VRVLsDHLQDSNAKGAI 244
Cdd:PRK12323 241 AVRGMLGAIDQSYlVRLL-DALAAEDGAALL 270
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
5-282 1.28e-84

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 264.12  E-value: 1.28e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   5 VLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN------------------ 66
Cdd:PRK14956   7 VLSRKYRPQFFRDVIHQDLAIGALQNALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENpignepcnectscleitk 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  67 ---LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPA 143
Cdd:PRK14956  87 gisSDVLEIDAASNRGIENIRELRDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHKIPE 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 144 TIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEELLGAI 223
Cdd:PRK14956 167 TILSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQAIVFTDSKLTGVKIRKMIGYH 246
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 224 DFEKVRVLSDHLQD-SNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKvdSSLVD 282
Cdd:PRK14956 247 GIEFLTSFIKSLIDpDNHSKSLEILESLYQEGQDIYKFLWDSIEFTHTLNLIR--DSLAD 304
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
1-339 4.88e-84

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 258.65  E-value: 4.88e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLY-RKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSNLD---------LL 70
Cdd:PRK14970   1 MENFVVSaRKYRPQTFDDVVGQSHITNTLLNAIENNHLAQALLFCGPRGVGKTTCARILARKINQPGYDdpnedfsfnIF 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  71 EIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQ 150
Cdd:PRK14970  81 ELDAASNNSVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 151 QFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEELLGAIDFEKVRV 230
Cdd:PRK14970 161 IFDFKRITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSIFDRVVTFCGKNITRQAVTENLNILDYDTYIN 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 231 LSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKVDSSLVDLMSQELTVDQVEIvkkQAESFSLNNVAQ 310
Cdd:PRK14970 241 VTDLILENKIPELLLAFNEILRKGFDGHHFIAGLASHFRDLMVSKTPATIALLEVGEQAKKRYEV---QSQKVSQSFLLS 317
                        330       340
                 ....*....|....*....|....*....
gi 818621560 311 AIKIFTNARNDIKRSPIPSLPIELAVVEI 339
Cdd:PRK14970 318 GIDIANDCDLKYKLSKNQRLLVELALMQL 346
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
1-343 7.91e-84

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 265.17  E-value: 7.91e-84
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSNL------------- 67
Cdd:PRK05896   1 MSEITFYRKYRPHNFKQIIGQELIKKILVNAILNNKLTHAYIFSGPRGIGKTSIAKIFAKAINCLNPkdgdccnscsvce 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  68 --------DLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAH 139
Cdd:PRK05896  81 sintnqsvDIVELDAASNNGVDEIRNIIDNINYLPTTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQ 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 140 KVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEEL 219
Cdd:PRK05896 161 KIPLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSEIDIEDINKT 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 220 LGAIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIML---IKVDSSLVDLMSQELTVDQVEIV 296
Cdd:PRK05896 241 FGLVDNNKKINLIELIQKNDIEELRNLINELESKGINFEAFCRDLINLLIDLLVyqkTKNINLLKKLSKEQLKTLNLEKQ 320
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*..
gi 818621560 297 KKQAESFSLNNVAQAikiFTNARNDIKRSPIPSLPIELAVVEIINNK 343
Cdd:PRK05896 321 KLLSIEFNTNFLLNN---FVSLINRLKASVNQVFEFEIYLYKIINAN 364
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
5-240 1.14e-83

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 263.05  E-value: 1.14e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   5 VLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGC-------------------- 64
Cdd:PRK08451   3 ALALKYRPKHFDELIGQESVSKTLSLALDNNRLAHAYLFSGLRGSGKTSSARIFARALVCeqgpsstpcdtciqcqsale 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  65 -SNLDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPA 143
Cdd:PRK08451  83 nRHIDIIEMDAASNRGIDDIRELIEQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKLPA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 144 TIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEELLGAI 223
Cdd:PRK08451 163 TILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQAIIYCKNAITESKVADMLGLL 242
                        250
                 ....*....|....*....
gi 818621560 224 DFEKVRVLSDHL--QDSNA 240
Cdd:PRK08451 243 DPSKLEDFFQAIlnQDKEK 261
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
1-245 9.41e-83

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 262.73  E-value: 9.41e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN-------------- 66
Cdd:PRK14951   1 MSYLVLARKYRPRSFSEMVGQEHVVQALTNALTQQRLHHAYLFTGTRGVGKTTVSRILAKSLNCQGpdgqggitatpcgv 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  67 ------------LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILA 134
Cdd:PRK14951  81 cqacrdidsgrfVDYTELDAASNRGVDEVQQLLEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 135 TTEAHKVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKE 214
Cdd:PRK14951 161 TTDPQKVPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQAIAFGSGQLQEA 240
                        250       260       270
                 ....*....|....*....|....*....|.
gi 818621560 215 DIEELLGAIDFEKVRVLSDHLQDSNAKGAID 245
Cdd:PRK14951 241 AVRQMLGSVDRSHVFRLIDALAQGDGRTVVE 271
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
1-341 1.23e-82

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 255.12  E-value: 1.23e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN-------------- 66
Cdd:PRK14961   1 MNYQILARKWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAWLLSGTRGVGKTTIARLLAKSLNCQNgitsnpcrkciick 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  67 -------LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAH 139
Cdd:PRK14961  81 eiekglcLDLIEIDAASRTKVEEMREILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 140 KVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEEL 219
Cdd:PRK14961 161 KIPKTILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGKGNINIKNVTDM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 220 LGAIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEvfaKAFINHLRKIMLIKVDSSLVDLMSQELTVDQVEIVKKQ 299
Cdd:PRK14961 241 LGLLNEKQSFLLTDALLKKDSKKTMLLLNKISSIGIEWE---NILIEMLRFLHHISMSQSFPKIWNTIFIKNYKNQIQKI 317
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 818621560 300 AESFSLNNVAQAIKIFTNARNDIKRSPIPSLPIELAVVEIIN 341
Cdd:PRK14961 318 AQNNKKTNIQLCYQILLNGRKELKFAPDQKIGVEMTLLRAIN 359
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
4-311 3.12e-80

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 260.69  E-value: 3.12e-80
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   4 LVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGC------------------- 64
Cdd:PRK07764   3 LALYRRYRPATFAEVIGQEHVTEPLSTALDSGRINHAYLFSGPRGCGKTSSARILARSLNCvegptstpcgecdscvala 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  65 ----SNLDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHK 140
Cdd:PRK07764  83 pggpGSLDVTEIDAASHGGVDDARELRERAFFAPAESRYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKFIFATTEPDK 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 141 VPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLriwnenM-------ITK 213
Cdd:PRK07764 163 VIGTIRSRTHHYPFRLVPPEVMRGYLERICAQEGVPVEPGVLPLVIRAGGGSVRDSLSVLDQL------LagagpegVTY 236
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 214 EDIEELLGAIDF----EKVrvlsDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIK-----VDSSLVDlM 284
Cdd:PRK07764 237 ERAVALLGVTDSalidEAV----DALAAGDGAALFGTVDRVIEAGHDPRRFAEDLLERLRDLIVLQavpdaAERGLVD-A 311
                        330       340
                 ....*....|....*....|....*..
gi 818621560 285 SqeltVDQVEIVKKQAESFSLNNVAQA 311
Cdd:PRK07764 312 P----ADQLDRMRAQAQRLGPAELTRA 334
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
1-339 2.91e-79

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 253.83  E-value: 2.91e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCS--------------- 65
Cdd:PRK14959   1 MSHASLTARYRPQTFAEVAGQETVKAILSRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALNCEtaptgepcntceqcr 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  66 ------NLDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAH 139
Cdd:PRK14959  81 kvtqgmHVDVVEIDGASNRGIDDAKRLKEAIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 140 KVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEEL 219
Cdd:PRK14959 161 KFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGESRLTIDGARGV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 220 LGAIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKvDSSLVDLMSQELTVDQVEIVKKQ 299
Cdd:PRK14959 241 LGLAGQELFLRLMEALAAQDCLGVANVVRELLDRGVDMGFFLRELVATWRNLFMLR-QAGEAALASLDLPEDEARQWLGW 319
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|
gi 818621560 300 AESFSLNNVAQAIKIFTNARNDIKRSPIPSLPIELAVVEI 339
Cdd:PRK14959 320 AKRFEPAHIHACWQMTLEGQRRVLTSLEPAMALELLLLNL 359
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
6-334 3.04e-77

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 247.49  E-value: 3.04e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   6 LYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCS-------------------- 65
Cdd:PRK14952   3 LYRKYRPATFAEVVGQEHVTEPLSSALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAqgptatpcgvcescvalapn 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  66 ---NLDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVP 142
Cdd:PRK14952  83 gpgSIDVVELDAASHGGVDDTRELRDRAFYAPAQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKVL 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 143 ATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNE-NMITKEDIEELLG 221
Cdd:PRK14952 163 PTIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLLAGAAdTHVTYQRALGLLG 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 222 AIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKvdsSLVDLMSQ---ELTVDQVEIVKK 298
Cdd:PRK14952 243 ATDVALIDDAVDALAADDAAALFGAIESVIDAGHDPRRFATDLLERFRDLIVLQ---AVPDAAARgvvDAPEDVLERMRE 319
                        330       340       350
                 ....*....|....*....|....*....|....*.
gi 818621560 299 QAESFSLNNVAQAIKIFTNARNDIKRSPIPSLPIEL 334
Cdd:PRK14952 320 QAARIGLATLTRYAEVVQAGLGEMRGATAPRLLLEV 355
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
5-224 3.27e-77

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 250.35  E-value: 3.27e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   5 VLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN------------------ 66
Cdd:PRK14960   4 VLARKYRPRNFNELVGQNHVSRALSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETgvtstpcevcatckavne 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  67 ---LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPA 143
Cdd:PRK14960  84 grfIDLIEIDAASRTKVEDTRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPI 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 144 TIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEELLGAI 223
Cdd:PRK14960 164 TVISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQGAVHHQDVKEMLGLI 243

                 .
gi 818621560 224 D 224
Cdd:PRK14960 244 D 244
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
5-239 9.89e-76

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 249.00  E-value: 9.89e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   5 VLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN------------------ 66
Cdd:PRK07003   5 VLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETgvtsqpcgvcracreide 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  67 ---LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPA 143
Cdd:PRK07003  85 grfVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPV 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 144 TIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEELLGAI 223
Cdd:PRK07003 165 TVLSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTETAVSGMLGAL 244
                        250
                 ....*....|....*.
gi 818621560 224 DFEKVRVLSDHLQDSN 239
Cdd:PRK07003 245 DQTYMVRLLDALAAGD 260
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
8-274 1.30e-74

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 238.61  E-value: 1.30e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   8 RKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSNL-------------------- 67
Cdd:PRK06645  13 RKYRPSNFAELQGQEVLVKVLSYTILNDRLAGGYLLTGIRGVGKTTSARIIAKAVNCSALitenttiktceqctncisfn 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  68 -----DLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVP 142
Cdd:PRK06645  93 nhnhpDIIEIDAASKTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATTEVQKIP 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 143 ATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWN---ENMITKEDIEEL 219
Cdd:PRK06645 173 ATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAASMSaksDNIISPQVINQM 252
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 818621560 220 LGAIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKA---FINHLRKIMLI 274
Cdd:PRK06645 253 LGLVDSSVIIEFVEYIIHRETEKAINLINKLYGSSVNLEIFIESvsdFIAYLNKVKML 310
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
3-260 1.57e-72

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 232.75  E-value: 1.57e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   3 NLVLyrKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGC------------------ 64
Cdd:PRK14964   2 NLAL--KYRPSSFKDLVGQDVLVRILRNAFTLNKIPQSILLVGASGVGKTTCARIISLCLNCsngptsdpcgtchncisi 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  65 ---SNLDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKV 141
Cdd:PRK14964  80 knsNHPDVIEIDAASNTSVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKI 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 142 PATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEELLG 221
Cdd:PRK14964 160 PVTIISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAAIYSNNKISEKSVRDLLG 239
                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 818621560 222 AIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVF 260
Cdd:PRK14964 240 CVDKHILEDLVEAILLGDAQSALNVFRELCNTSNPVIIL 278
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
1-340 5.72e-70

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 227.66  E-value: 5.72e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGC---------------- 64
Cdd:PRK14957   1 MSYQALARKYRPQSFAEVAGQQHALNSLVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCktgvtaepcnkcencv 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  65 -----SNLDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAH 139
Cdd:PRK14957  81 ainnnSFIDLIEIDAASRTGVEETKEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 140 KVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEEL 219
Cdd:PRK14957 161 KIPVTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGGELKQAQIKQM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 220 LGAIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAgvdlEVFAKAFINHLRKIMLIKVDSSLVDLMSQELTVDqVEIVKKQ 299
Cdd:PRK14957 241 LGIIDSEEVYSIINAIIDNDPKAILPAIKNLALT----ESSADAVLDRIAEIWFACCIYSFTQSLDAVNDID-VDIINNI 315
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 818621560 300 AESFSLNNVAQAIKIFTNARNDIKRSPIPSLPIELAVVEII 340
Cdd:PRK14957 316 LAKISIEQAHFLYQLTITAKKDIALAPNFETGVTMAILRLI 356
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
5-224 3.59e-68

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 230.00  E-value: 3.59e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   5 VLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN------------------ 66
Cdd:PRK14949   5 VLARKWRPATFEQMVGQSHVLHALTNALTQQRLHHAYLFTGTRGVGKTSLARLFAKGLNCEQgvtatpcgvcsscveiaq 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  67 ---LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPA 143
Cdd:PRK14949  85 grfVDLIEVDAASRTKVDDTRELLDNVQYRPSRGRFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFLLATTDPQKLPV 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 144 TIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEELLGAI 223
Cdd:PRK14949 165 TVLSRCLQFNLKSLTQDEIGTQLNHILTQEQLPFEAEALTLLAKAANGSMRDALSLTDQAIAFGGGQVMLTQVQTMLGSI 244

                 .
gi 818621560 224 D 224
Cdd:PRK14949 245 D 245
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
1-340 4.31e-66

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 216.52  E-value: 4.31e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN-------------- 66
Cdd:PRK14958   1 MAHQVLARKWRPRCFQEVIGQAPVVRALSNALDQQYLHHAYLFTGTRGVGKTTISRILAKCLNCEKgvsanpcndcencr 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  67 -------LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAH 139
Cdd:PRK14958  81 eidegrfPDLFEVDAASRTKVEDTRELLDNIPYAPTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 140 KVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEEL 219
Cdd:PRK14958 161 KLPVTVLSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQSIAYGNGKVLIADVKTM 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 220 LGAIDfekVRVLSDHLQDSNAKGAIDYIG---KLIEAGVDlevfakaFINHLRKIMLIKVDSSLVDLMSQELTVDQVEIV 296
Cdd:PRK14958 241 LGTIE---PLLLFDILEALAAKAGDRLLGcvtRLVEQGVD-------FSNALADLLSLLHQIAIIQTVPEALIENDSEQL 310
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 818621560 297 KKQAESFSLNNVAQAIKIFTNARNDIKRSPIPSLPIELAVVEII 340
Cdd:PRK14958 311 RQLAKLLDREDVQLFYQIGLIGQRDLAYSPTPQTGFEMTLLRML 354
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
21-252 8.32e-52

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 173.24  E-value: 8.32e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  21 QEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSN--------------------LDLLEI---DAASN 77
Cdd:COG0470    1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENpeggkacgqchsrlmaagnhPDLLELnpeEKSDQ 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  78 RGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQQFTFKKL 157
Cdd:COG0470   81 IGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFRPP 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 158 AITDIVKKLQkiveaeKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMitkEDIEELLGAIDFEKvrvLSDHLQD 237
Cdd:COG0470  161 SEEEALAWLR------EEGVDEDALEAILRLAGGDPRAAINLLQALAGRKELL---EDLAALLSRDRALE---LLDALLK 228
                        250
                 ....*....|....*
gi 818621560 238 SNAKGAIDYIGKLIE 252
Cdd:COG0470  229 AEALELLDWLLKWLL 243
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
20-158 3.72e-42

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 143.89  E-value: 3.72e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   20 GQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSNL---------------------DLLEIDAASNR 78
Cdd:pfam13177   1 GQPEAIQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPgddlpcgqcrscrriesgnhpDLVIIEPEGQS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   79 -GIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQQFTFKKL 157
Cdd:pfam13177  81 iKIDQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPL 160

                  .
gi 818621560  158 A 158
Cdd:pfam13177 161 S 161
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
26-196 2.72e-41

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 142.77  E-value: 2.72e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   26 RTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSNL---------------------DLLEIDAASNR-GIDEI 83
Cdd:TIGR00678   2 QQLKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRgggepcgechscrlieagnhpDLHRLEPEGQSiKVDQV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   84 RQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQQFTFKKLAITDIV 163
Cdd:TIGR00678  82 RELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEALL 161
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 818621560  164 KKLQK--IVEAekikinddALRLVASYADGSYRDA 196
Cdd:TIGR00678 162 QWLIRqgISEE--------AAELLLALAGGSPGRA 188
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
9-258 8.59e-39

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 142.15  E-value: 8.59e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   9 KYRPQSWEEIIGQEHIV---RTLTNALKLGRVnHAYLFSGPRGTGKTTIARLLAKSVgcsNLDLLEIDAASNrGIDEIRQ 85
Cdd:PRK13342   5 RMRPKTLDEVVGQEHLLgpgKPLRRMIEAGRL-SSMILWGPPGTGKTTLARIIAGAT---DAPFEALSAVTS-GVKDLRE 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  86 LRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEppAHAIFILATTE--AHKVPATIVSRVQQFTFKKLAITDIV 163
Cdd:PRK13342  80 VIEEARQRRSAGRRTILFIDEIHRFNKAQQDALLPHVED--GTITLIGATTEnpSFEVNPALLSRAQVFELKPLSEEDIE 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 164 KKLQKIVEAEK---IKINDDALRLVASYADGSYRDAESMLEQLRIWNENmITKEDIEELLGaidfeKVRVLSDHLQD--- 237
Cdd:PRK13342 158 QLLKRALEDKErglVELDDEALDALARLANGDARRALNLLELAALGVDS-ITLELLEEALQ-----KRAARYDKDGDehy 231
                        250       260       270
                 ....*....|....*....|....*....|...
gi 818621560 238 ------------SNAKGAIDYIGKLIEAGVDLE 258
Cdd:PRK13342 232 dlisalhksirgSDPDAALYYLARMLEAGEDPL 264
PRK12402 PRK12402
replication factor C small subunit 2; Reviewed
9-282 5.43e-33

replication factor C small subunit 2; Reviewed


Pssm-ID: 237090 [Multi-domain]  Cd Length: 337  Bit Score: 125.10  E-value: 5.43e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   9 KYRPQSWEEIIGQEHIVRTLTNALKLGRVNHaYLFSGPRGTGKTTIARLLAKSVGCSNL--DLLEIDAAS--NRGIDEIR 84
Cdd:PRK12402   8 KYRPALLEDILGQDEVVERLSRAVDSPNLPH-LLVQGPPGSGKTAAVRALARELYGDPWenNFTEFNVADffDQGKKYLV 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  85 Q-----------------LRDGIK--------FAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAH 139
Cdd:PRK12402  87 EdprfahflgtdkrirssKIDNFKhvlkeyasYRPLSADYKTILLDNAEALREDAQQALRRIMEQYSRTCRFIIATRQPS 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 140 KVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLeQLRIWNENMITKEDIEEL 219
Cdd:PRK12402 167 KLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTL-QTAALAAGEITMEAAYEA 245
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 818621560 220 LGAIDF-EKVRVLSDHLQDSNAKGAIDYIGKL-IEAGVD--------LEVFAKAFI--NHLRKIMLI-KVDSSLVD 282
Cdd:PRK12402 246 LGDVGTdEVIESLLDAAEAGDFTDARKTLDDLlIDEGLSggevleelLRVARSRYRgdNLARLHRLAaDADARLTD 321
rfc PRK00440
replication factor C small subunit; Reviewed
1-229 1.34e-32

replication factor C small subunit; Reviewed


Pssm-ID: 234763 [Multi-domain]  Cd Length: 319  Bit Score: 123.44  E-value: 1.34e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHaYLFSGPRGTGKTTIARLLAKSVGCSNL--DLLEIDAASNR 78
Cdd:PRK00440   2 MMEEIWVEKYRPRTLDEIVGQEEIVERLKSYVKEKNMPH-LLFAGPPGTGKTTAALALARELYGEDWreNFLELNASDER 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  79 GIDEIRqlrDGIK-FAPTA--GK--YKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQQFT 153
Cdd:PRK00440  81 GIDVIR---NKIKeFARTApvGGapFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPIQSRCAVFR 157
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 818621560 154 FKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENmITKEDIEELLGAIDFEKVR 229
Cdd:PRK00440 158 FSPLKKEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINALQAAAATGKE-VTEEAVYKITGTARPEEIR 232
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
11-257 4.86e-30

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 118.62  E-value: 4.86e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  11 RPQSWEEIIGQEHIV---RTLTNALKLGRVnHAYLFSGPRGTGKTTIARLLAKSvgcSNLDLLEIDAASNrGIDEIRQLR 87
Cdd:COG2256   20 RPRTLDEVVGQEHLLgpgKPLRRAIEAGRL-SSMILWGPPGTGKTTLARLIANA---TDAEFVALSAVTS-GVKDIREVI 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  88 DGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEppAHAIFILATTE--AHKVPATIVSRVQQFTFKKLAITDIVKK 165
Cdd:COG2256   95 EEARERRAYGRRTILFVDEIHRFNKAQQDALLPHVED--GTITLIGATTEnpSFEVNSALLSRCRVFVLKPLSEEDLEQL 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 166 LQKIVE-------AEKIKINDDALRLVASYADGSYRDAESMLEQL----RIWNENMITKEDIEELLG--AIDFEK----- 227
Cdd:COG2256  173 LERALAdderglgGYKLELDDEALEALARLADGDARRALNALELAvlsaPPDGVIEITLELVEEALQrrALRYDKdgdeh 252
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 818621560 228 ----------VRvlsdhlqDSNAKGAIDYIGKLIEAGVDL 257
Cdd:COG2256  253 ydlisafiksIR-------GSDPDAALYWLARMLEAGEDP 285
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
15-208 7.45e-29

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 113.46  E-value: 7.45e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  15 WEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIAR-----LLAKSVGCSNL----------DLL--------- 70
Cdd:PRK07399   3 FANLIGQPLAIELLTAAIKQNRIAPAYLFAGPEGVGRKLAALcfiegLLSQGSPSKNIrrrleegnhpDLLwveptyqhq 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  71 ---------EIDAASNRGIDEIR--QLRDGIKF---APTAGKYKVFIIDEAHQLTKEAFNALLKTLEEpPAHAIFILATT 136
Cdd:PRK07399  83 gklitaseaEEAGLKRKAPPQIRleQIREIKRFlsrPPLEAPRKVVVIEDAETMNEAAANALLKTLEE-PGNGTLILIAP 161
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 818621560 137 EAHKVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDAlrLVASyADGSyrdAESMLEQLRIWNE 208
Cdd:PRK07399 162 SPESLLPTIVSRCQIIPFYRLSDEQLEQVLKRLGDEEILNINFPE--LLAL-AQGS---PGAAIANIEQLQS 227
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
13-168 2.29e-28

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 112.33  E-value: 2.29e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  13 QSWEEIIG-QEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSNL---------------------DLL 70
Cdd:PRK08058   2 MTWEQLTAlQPVVVKMLQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERngvepcgtctnckridsgnhpDVH 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  71 EI--DAASNRgIDEIRQLRDgiKFAPTA--GKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIV 146
Cdd:PRK08058  82 LVapDGQSIK-KDQIRYLKE--EFSKSGveSNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTIL 158
                        170       180
                 ....*....|....*....|..
gi 818621560 147 SRVQQFTFKKLAITDIVKKLQK 168
Cdd:PRK08058 159 SRCQVVEFRPLPPESLIQRLQE 180
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
14-330 9.74e-26

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 104.73  E-value: 9.74e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  14 SWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIAR-----LLAKSVGCSNLDLLEIDAASNR--GIDEIRQL 86
Cdd:PRK05564   2 SFHTIIGHENIKNRIKNSIIKNRFSHAHIIVGEDGIGKSLLAKeialkILGKSQQREYVDIIEFKPINKKsiGVDDIRNI 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  87 RDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQQFTFKKLAITDIvkkl 166
Cdd:PRK05564  82 IEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYKLNRLSKEEI---- 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 167 QKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEEllgaidfekvrvlsdhLQDSNAKGAIDY 246
Cdd:PRK05564 158 EKFISYKYNDIKEEEKKSAIAFSDGIPGKVEKFIEDDSLKNIRNMSLEILKD----------------IKKSNINILLKY 221
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 247 IGKLIEAGVDLEVFAKAFINHLRKIMLIKvdsslvDLMSQELTV--DQVEIVKKQAESFSLNNVAQAIKIFTNARNDIKR 324
Cdd:PRK05564 222 ENFLIKYKENWEEILTCILSYIRDSLLYK------ETGNEELIIniDKIEDIKHISEKFSYKKLNKMIEIINDTRDNLSS 295

                 ....*.
gi 818621560 325 SPIPSL 330
Cdd:PRK05564 296 NVNPTL 301
PLN03025 PLN03025
replication factor C subunit; Provisional
9-196 6.29e-24

replication factor C subunit; Provisional


Pssm-ID: 178596 [Multi-domain]  Cd Length: 319  Bit Score: 99.80  E-value: 6.29e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   9 KYRPQSWEEIIGQEHIVRTLTNALKLGRVNHaYLFSGPRGTGKTTIARLLAKSVGCSNLD--LLEIDAASNRGIDEIRql 86
Cdd:PLN03025   6 KYRPTKLDDIVGNEDAVSRLQVIARDGNMPN-LILSGPPGTGKTTSILALAHELLGPNYKeaVLELNASDDRGIDVVR-- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  87 rDGIK-FAPT-----AGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQQFTFKKLAIT 160
Cdd:PLN03025  83 -NKIKmFAQKkvtlpPGRHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIEPIQSRCAIVRFSRLSDQ 161
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 818621560 161 DIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDA 196
Cdd:PLN03025 162 EILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQA 197
44 PHA02544
clamp loader, small subunit; Provisional
1-233 7.63e-22

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 94.29  E-value: 7.63e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   1 MGNLVLYRKYRPQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCsnlDLLEIDAASNRgI 80
Cdd:PHA02544   6 PNEFMWEQKYRPSTIDECILPAADKETFKSIVKKGRIPNMLLHSPSPGTGKTTVAKALCNEVGA---EVLFVNGSDCR-I 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  81 DEIRQlrDGIKFAPTA---GKYKVFIIDEAHQL-TKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQQFTF-- 154
Cdd:PHA02544  82 DFVRN--RLTRFASTVsltGGGKVIIIDEFDRLgLADAQRHLRSFMEAYSKNCSFIITANNKNGIIEPLRSRCRVIDFgv 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 155 ----KKLAI-TDIVKKLQKIVEAEKIKINddaLRLVASYADGSYRDAESMLEQLRIWNEN---------MITKEDIEELL 220
Cdd:PHA02544 160 ptkeEQIEMmKQMIVRCKGILEAEGVEVD---MKVLAALVKKNFPDFRRTINELQRYASTgkidagilsEVTNSDIDDVV 236
                        250
                 ....*....|....*.
gi 818621560 221 GAI---DFEKVRVLSD 233
Cdd:PHA02544 237 EALkakDFKAVRALAP 252
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
12-196 2.39e-21

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 93.18  E-value: 2.39e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  12 PQSWEEIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVgCSNLD-------LLEIDAAS-------- 76
Cdd:PRK09112  19 PSENTRLFGHEEAEAFLAQAYREGKLHHALLFEGPEGIGKATLAFHLANHI-LSHPDpaeapetLADPDPASpvwrqiaq 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  77 ---------NRGIDE----------IRQLRDGIKF---APTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILA 134
Cdd:PRK09112  98 gahpnllhiTRPFDEktgkfktaitVDEIRRVGHFlsqTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILI 177
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 818621560 135 TTEAHKVPATIVSRVQQFTFKKLAITDIVKKLQKIveAEKIKINDDALRLVASYADGSYRDA 196
Cdd:PRK09112 178 SHSSGRLLPTIRSRCQPISLKPLDDDELKKALSHL--GSSQGSDGEITEALLQRSKGSVRKA 237
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
15-150 6.99e-21

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 92.28  E-value: 6.99e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  15 WEEIIGQEHIVRTLTNA---------LKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSNLDL---------------- 69
Cdd:PRK07940   4 WDDLVGQEAVVAELRAAaraaradvaAAGSGMTHAWLFTGPPGSGRSVAARAFAAALQCTDPDEpgcgecracrtvlagt 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  70 -----------LEIdaasnrGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEA 138
Cdd:PRK07940  84 hpdvrvvapegLSI------GVDEVRELVTIAARRPSTGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSP 157
                        170
                 ....*....|..
gi 818621560 139 HKVPATIVSRVQ 150
Cdd:PRK07940 158 EDVLPTIRSRCR 169
PRK13341 PRK13341
AAA family ATPase;
11-256 2.15e-20

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 92.43  E-value: 2.15e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  11 RPQSWEEIIGQEHIV---RTLTNALKLGRVNHAyLFSGPRGTGKTTIARLLAKSVGC--SNLDlleidaASNRGIDEIR- 84
Cdd:PRK13341  23 RPRTLEEFVGQDHILgegRLLRRAIKADRVGSL-ILYGPPGVGKTTLARIIANHTRAhfSSLN------AVLAGVKDLRa 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  85 QLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEppAHAIFILATTE--AHKVPATIVSRVQQFTFKKLAITDI 162
Cdd:PRK13341  96 EVDRAKERLERHGKRTILFIDEVHRFNKAQQDALLPWVEN--GTITLIGATTEnpYFEVNKALVSRSRLFRLKSLSDEDL 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 163 VKKLQKIVEAE-------KIKINDDALRLVASYADGsyrDAESMLEQLRIWNENMITKED-IEELLGAIDFEKVR---VL 231
Cdd:PRK13341 174 HQLLKRALQDKergygdrKVDLEPEAEKHLVDVANG---DARSLLNALELAVESTPPDEDgLIDITLAIAEESIQqraVL 250
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 818621560 232 SD-----H----------LQDSNAKGAIDYIGKLIEAGVD 256
Cdd:PRK13341 251 YDkegdaHfdtisafiksLRGSDPDAALYWLARMVEAGED 290
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
17-192 3.15e-19

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 87.39  E-value: 3.15e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  17 EIIGQEHIVRTLTNALKLGRVNHAYLFSGPRGTGKTT----IAR-LLAKSVGCSNL------------------------ 67
Cdd:PRK07471  20 ALFGHAAAEAALLDAYRSGRLHHAWLIGGPQGIGKATlayrMARfLLATPPPGGDGavppptslaidpdhpvarriaaga 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  68 --DLLEIDAASNRG---------IDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATT 136
Cdd:PRK07471 100 hgGLLTLERSWNEKgkrlrtvitVDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPARSLFLLVSH 179
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 818621560 137 EAHKVPATIVSRVQQFTFKKLAITDIVKKL-QKIVEAEkikinDDALRLVASYADGS 192
Cdd:PRK07471 180 APARLLPTIRSRCRKLRLRPLAPEDVIDALaAAGPDLP-----DDPRAALAALAEGS 231
PRK04195 PRK04195
replication factor C large subunit; Provisional
9-221 7.57e-19

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 87.28  E-value: 7.57e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   9 KYRPQSWEEIIGQEHIVRTLT---NALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGcsnLDLLEIDAASNRGIDEIRQ 85
Cdd:PRK04195   7 KYRPKTLSDVVGNEKAKEQLRewiESWLKGKPKKALLLYGPPGVGKTSLAHALANDYG---WEVIELNASDQRTADVIER 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  86 --LRDGIKFAPTAGKYKVFIIDEAHQLTK-------EAFNALLKTLEEPpahaiFILATTEAHKVP-ATIVSRVQQFTFK 155
Cdd:PRK04195  84 vaGEAATSGSLFGARRKLILLDEVDGIHGnedrggaRAILELIKKAKQP-----IILTANDPYDPSlRELRNACLMIEFK 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 818621560 156 KLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENmITKEDIEELLG 221
Cdd:PRK04195 159 RLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSAINDLQAIAEGYGK-LTLEDVKTLGR 223
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
19-136 3.59e-17

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 77.57  E-value: 3.59e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  19 IGQEHIVRTLTNALKLGRVNHaYLFSGPRGTGKTTIARLLAKSVGCSNLDLLEIDAASNRGIDEIR-----QLRDGIKFA 93
Cdd:cd00009    1 VGQEEAIEALREALELPPPKN-LLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAelfghFLVRLLFEL 79
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 818621560  94 PTAGKYKVFIIDEAHQLTKEAFNALLKTLEE------PPAHAIFILATT 136
Cdd:cd00009   80 AEKAKPGVLFIDEIDSLSRGAQNALLRVLETlndlriDRENVRVIGATN 128
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
35-154 1.22e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 79.36  E-value: 1.22e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  35 GRVNHAYLFSGPRGTGKTTIARLLAKSVGCS------------------------NLDLLEIDAASNRGIDEIRQLRDGI 90
Cdd:PRK05707  19 GRHPHAYLLHGPAGIGKRALAERLAAALLCEapqgggacgsckgcqllragshpdNFVLEPEEADKTIKVDQVRELVSFV 98
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 818621560  91 KFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQQFTF 154
Cdd:PRK05707  99 VQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQAC 162
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
31-155 9.36e-16

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 76.92  E-value: 9.36e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  31 ALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCSNL------------------DLLEIDAASNRG---------IDEI 83
Cdd:PRK08769  19 ALDAGRLGHGLLICGPEGLGKRAVALALAEHVLASGPdpaaaqrtrqliaagthpDLQLVSFIPNRTgdklrteivIEQV 98
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 818621560  84 RQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQQFTFK 155
Cdd:PRK08769  99 REISQKLALTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCQRLEFK 170
HLD_clamp_pol_III_gamma_tau cd18137
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ...
161-221 1.22e-15

helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.


Pssm-ID: 350839 [Multi-domain]  Cd Length: 65  Bit Score: 70.61  E-value: 1.22e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 818621560 161 DIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENMITKEDIEELLG 221
Cdd:cd18137    5 DIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGGRVTLDDVREMLG 65
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
36-152 1.23e-15

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 76.45  E-value: 1.23e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  36 RVNHAYLFSGPRGTGKTTIARLLAKSVGC----------------------SNLDLLEIDAASNR----------GIDEI 83
Cdd:PRK08699  19 RRPNAWLFAGKKGIGKTAFARFAAQALLCetpapghkpcgecmschlfgqgSHPDFYEITPLSDEpengrkllqiKIDAV 98
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 818621560  84 RQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQQF 152
Cdd:PRK08699  99 REIIDNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKM 167
HolA COG1466
DNA polymerase III, delta subunit [Replication, recombination and repair];
97-328 1.66e-14

DNA polymerase III, delta subunit [Replication, recombination and repair];


Pssm-ID: 441075 [Multi-domain]  Cd Length: 305  Bit Score: 72.98  E-value: 1.66e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  97 GKYKVFIIDEAHQLTK--EAFNALLKTLEEPPAHAIFILAT---TEAHKVPATIVSRVQQFTFKKLAITDIVKKLQKIVE 171
Cdd:COG1466   61 GERRLVIVRNAEFLKKpgEGLEALEAYLANPPPDTVLVLTAgklDKRKKLFKALEKAGVVVECYPLKERELPAWIRQRLK 140
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 172 AEKIKINDDALRLVASYADGSYRDAESMLEQLRI--WNENMITKEDIEELLGAIDFEKVRVLSDHLQDSNAKGAIDYIGK 249
Cdd:COG1466  141 AAGLRIDPDAAQLLAERVGGDLLALAQELEKLALyaGDGGTITLEDVEALVGDSAEFNVFDLADALLAGDAARALRILRR 220
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 250 LIEAGVDLEVFAKAFINHLRKIMLIKVDSSL---VDLMSQELTVD--QVEIVKKQAESFSLNNVAQAIKIFTNARNDIKR 324
Cdd:COG1466  221 LLAEGEEPVLILAALARQFRLLLQVKALLAQgksLAEIAKELGVPpfRVKLALRALRRWSLERLARALQLLAEADLALKG 300

                 ....
gi 818621560 325 SPIP 328
Cdd:COG1466  301 GAAD 304
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
22-150 2.80e-14

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 72.46  E-value: 2.80e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  22 EHIVRTLTNALKLGRVNHAYLFSGPRGTGKTTIARLLAKSVGC---------------------SNLDLLEIDAASNR-- 78
Cdd:PRK06871   8 QPTYQQITQAFQQGLGHHALLFKADSGLGTEQLIRALAQWLMCqtpqgdqpcgqchschlfqagNHPDFHILEPIDNKdi 87
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 818621560  79 GIDEIRQLRDGI-KFAPTAGKyKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQ 150
Cdd:PRK06871  88 GVDQVREINEKVsQHAQQGGN-KVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQ 159
PRK04132 PRK04132
replication factor C small subunit; Provisional
52-201 9.05e-14

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 72.18  E-value: 9.05e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  52 TTIARLLAKSVGCSNL--DLLEIDAASNRGIDEIR-QLRDGIKFAPTAG-KYKVFIIDEAHQLTKEAFNALLKTLEEPPA 127
Cdd:PRK04132 580 TTAALALARELFGENWrhNFLELNASDERGINVIReKVKEFARTKPIGGaSFKIIFLDEADALTQDAQQALRRTMEMFSS 659
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 818621560 128 HAIFILATTEAHKVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLE 201
Cdd:PRK04132 660 NVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINILQ 733
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
80-148 2.85e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 69.05  E-value: 2.85e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 818621560  80 IDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSR 148
Cdd:PRK05917  77 IETPRAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSR 145
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
32-206 3.51e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 68.89  E-value: 3.51e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  32 LKLGRVNHAYLFSGprGTGKTTIARLLAKSVGCSNLD------------LLE--------IDAASNRGI--DEIRQLRDG 89
Cdd:PRK07276  18 LEQDRLNHAYLFSG--DFASFEMALFLAQSLFCEQKEgvlpcghcrscrLIEqgefsdvtVIEPQGQVIktDTIRELVKN 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  90 IKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQQFTFKKlaitdIVKKLQKI 169
Cdd:PRK07276  96 FSQSGYEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFHFPK-----NEAYLIQL 170
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 818621560 170 VEAEKIkINDDAlRLVASYADgSYRDAESMLEQLRIW 206
Cdd:PRK07276 171 LEQKGL-LKTQA-ELLAKLAQ-STSEAEKLAQNKKFL 204
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
15-237 5.14e-13

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 67.99  E-value: 5.14e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  15 WEEIIGQE-------HIVRTLTNALKLGRVN----HAYLFSGPRGTGKTTIARLLAKSvgcSNLDLLEI----------- 72
Cdd:COG1223    1 LDDVVGQEeakkklkLIIKELRRRENLRKFGlwppRKILFYGPPGTGKTMLAEALAGE---LKLPLLTVrldsligsylg 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  73 DAASNrgideIRQLRDGIKFAPTagkykVFIIDEAHQL------------TKEAFNALLKTLEEPPAHAIFILATTEAHK 140
Cdd:COG1223   78 ETARN-----LRKLFDFARRAPC-----VIFFDEFDAIakdrgdqndvgeVKRVVNALLQELDGLPSGSVVIAATNHPEL 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 141 VPATIVSRVQQF-TFKKLAITDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLR----IWNENMITKED 215
Cdd:COG1223  148 LDSALWRRFDEViEFPLPDKEERKEILELNLKKFPLPFELDLKKLAKKLEGLSGADIEKVLKTALkkaiLEDREKVTKED 227
                        250       260
                 ....*....|....*....|..
gi 818621560 216 IEEllgAIDFEKVRVLSDHLQD 237
Cdd:COG1223  228 LEE---ALKQRKERKKEPKKEG 246
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
36-152 8.70e-13

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 68.25  E-value: 8.70e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  36 RVNHAYLFSGPRGTGKTTIARLLAKSVGCSNL-----------------------------DLLEIDAASNRG------- 79
Cdd:PRK06964  19 RLPHALLLHGQAGIGKLDFAQHLAQGLLCETPqpdgepcgtcaacnwfaqgnhpdyrivrpEALAAEAPGAADeakeada 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  80 ---------------IDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPAT 144
Cdd:PRK06964  99 deggkktkapskeikIEQVRALLDFCGVGTHRGGARVVVLYPAEALNVAAANALLKTLEEPPPGTVFLLVSARIDRLLPT 178

                 ....*...
gi 818621560 145 IVSRVQQF 152
Cdd:PRK06964 179 ILSRCRQF 186
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
8-226 1.20e-12

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 68.40  E-value: 1.20e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   8 RKYRPQSWEEIIGQEHIVRTLTNA-------------LKLGRVNHAyLFSGPRGTGKTTIARLLAKSVGcsnLDLLEIDA 74
Cdd:COG0464  149 LELREAILDDLGGLEEVKEELRELvalplkrpelreeYGLPPPRGL-LLYGPPGTGKTLLARALAGELG---LPLIEVDL 224
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  75 ASNRG-------------IDEIRQLRDGIKFaptagkykvfiIDEAHQL-----------TKEAFNALLKTLEEPPAHAI 130
Cdd:COG0464  225 SDLVSkyvgeteknlrevFDKARGLAPCVLF-----------IDEADALagkrgevgdgvGRRVVNTLLTEMEELRSDVV 293
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 131 FILATTEAHKVPATIVSRVQ-QFTFKKL---AITDIVKKLqkiveAEKIKINDDA-LRLVASYADG-SYRDAESMLEQLR 204
Cdd:COG0464  294 VIAATNRPDLLDPALLRRFDeIIFFPLPdaeERLEIFRIH-----LRKRPLDEDVdLEELAEATEGlSGADIRNVVRRAA 368
                        250       260
                 ....*....|....*....|....*.
gi 818621560 205 I----WNENMITKEDIEELLGAIDFE 226
Cdd:COG0464  369 LqalrLGREPVTTEDLLEALEREDIF 394
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
41-150 2.04e-12

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 63.38  E-value: 2.04e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   41 YLFSGPRGTGKTTIARLLAKSvgcSNLDLLEIDAAS--NRGIDE-IRQLRDGIKFAPTAGKyKVFIIDEAHQLTK----- 112
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKE---LGAPFIEISGSElvSKYVGEsEKRLRELFEAAKKLAP-CVIFIDEIDALAGsrgsg 76
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 818621560  113 ------EAFNALLKTLEEPPAHA---IFILATTEAHKVPATIVSRVQ 150
Cdd:pfam00004  77 gdsesrRVVNQLLTELDGFTSSNskvIVIAATNRPDKLDPALLGRFD 123
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
80-203 3.16e-12

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 66.37  E-value: 3.16e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  80 IDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQQFTFKKLAI 159
Cdd:PRK06090  90 VEQIRQCNRLAQESSQLNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVVTPPST 169
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 818621560 160 TDIVKKLQK---IVEAEKIKINDDA-LRLVASYADGSYRDAESMLEQL 203
Cdd:PRK06090 170 AQAMQWLKGqgiTVPAYALKLNMGSpLKTLAMMKEGGLEKYHKLERQL 217
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
76-148 6.84e-12

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 65.47  E-value: 6.84e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 818621560  76 SNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSR 148
Cdd:PRK07993  86 SSLGVDAVREVTEKLYEHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSR 158
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
96-166 1.25e-10

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 61.66  E-value: 1.25e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 818621560  96 AGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQQFTFKKLAITDIVKKL 166
Cdd:PRK07132  88 QSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKEPDQQKILAKL 158
ruvB PRK00080
Holliday junction branch migration DNA helicase RuvB;
11-224 1.00e-08

Holliday junction branch migration DNA helicase RuvB;


Pssm-ID: 234619 [Multi-domain]  Cd Length: 328  Bit Score: 55.91  E-value: 1.00e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  11 RPQSWEEIIGQEHIVRTL----TNALKLGRV-NHAyLFSGPRGTGKTTIARLLAKSVGcSNL------------DLLEId 73
Cdd:PRK00080  20 RPKSLDEFIGQEKVKENLkifiEAAKKRGEAlDHV-LLYGPPGLGKTTLANIIANEMG-VNIritsgpalekpgDLAAI- 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  74 aASNrgIDEirqlRDgikfaptagkykVFIIDEAHQLTKEAFNALLKTLE----------EPPAHAI------FIL--AT 135
Cdd:PRK00080  97 -LTN--LEE----GD------------VLFIDEIHRLSPVVEEILYPAMEdfrldimigkGPAARSIrldlppFTLigAT 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 136 TEAHKVPA------TIVSRVQQFTfkklaitdiVKKLQKIVE--AEK--IKINDDALRLVASYADGSYRDAESMLEQLR- 204
Cdd:PRK00080 158 TRAGLLTSplrdrfGIVQRLEFYT---------VEELEKIVKrsARIlgVEIDEEGALEIARRSRGTPRIANRLLRRVRd 228
                        250       260
                 ....*....|....*....|...
gi 818621560 205 ---IWNENMITKEDIEELLGAID 224
Cdd:PRK00080 229 faqVKGDGVITKEIADKALDMLG 251
PRK04132 PRK04132
replication factor C small subunit; Provisional
9-106 2.50e-07

replication factor C small subunit; Provisional


Pssm-ID: 235223 [Multi-domain]  Cd Length: 846  Bit Score: 52.53  E-value: 2.50e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   9 KYRPQSWEEIIGQEHIVRTLTNALKLGRVNHaYLFSGPRGTGKttiarllaksvgCSNLDLLEIDAASNRGIDEIRQLRD 88
Cdd:PRK04132  12 KYRPQRLDDIVGQEHIVKRLKHYVKTGSMPH-LLFAGPPGVGK------------CLTGDTKVIANGELFEIGELVEKIS 78
                         90
                 ....*....|....*....
gi 818621560  89 GIKFAPTAGK-YKVFIIDE 106
Cdd:PRK04132  79 NGKFGPTPVNgLKVLGIDE 97
PRK08485 PRK08485
DNA polymerase III subunit delta'; Validated
65-229 4.18e-07

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236274 [Multi-domain]  Cd Length: 206  Bit Score: 50.03  E-value: 4.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  65 SNLDLLEIDAASNRGIDEIR----------QLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILA 134
Cdd:PRK08485  11 SDFEESKEELINEFGKKNLRffikeefkieDAKEVIAEAYIAESEEKIIVIAAPSYGIEAQNALLKILEEPPKNICFIIV 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 135 TTEAHKVPATIVSRVQqftfkklaitdIVKKLQKIveaEKIKINDDALRLvasyadgSYRDAESMLEQLRiwNENMITKE 214
Cdd:PRK08485  91 AKSKNLLLPTIRSRLI-----------IEKRKQKK---PVKPLDLDLKKL-------DLKDIYEFLKELE--KENKLSKE 147
                        170
                 ....*....|....*
gi 818621560 215 DIEELLGAIDFEKVR 229
Cdd:PRK08485 148 ELKELIESLLKECVK 162
AAA_22 pfam13401
AAA domain;
42-141 4.46e-07

AAA domain;


Pssm-ID: 379165 [Multi-domain]  Cd Length: 129  Bit Score: 48.49  E-value: 4.46e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   42 LFSGPRGTGKTTIARLLAKSVGCSNLDLLEIDAASNRGIDEIRQ-------------------LRDGIKFAPTAGKYKVF 102
Cdd:pfam13401   9 VLTGESGTGKTTLLRRLLEQLPEVRDSVVFVDLPSGTSPKDLLRallralglplsgrlskeelLAALQQLLLALAVAVVL 88
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 818621560  103 IIDEAHQLTKEAFNALLKTLEEPPAHAIFILA-TTEAHKV 141
Cdd:pfam13401  89 IIDEAQHLSLEALEELRDLLNLSSKLLQLILVgTPELREL 128
COG2842 COG2842
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ...
42-218 9.58e-07

Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];


Pssm-ID: 442090 [Multi-domain]  Cd Length: 254  Bit Score: 49.18  E-value: 9.58e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  42 LFSGPRGTGKTTIARLLAK----------SVGCSNLDLLE-------IDAASNRGIDEIRQLRDgiKFAPTAGkykVFII 104
Cdd:COG2842   54 VVYGESGVGKTTAAREYANrnpnviyvtaSPSWTSKELLEelaeelgIPAPPGTIADLRDRILE--RLAGTGR---LLII 128
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 105 DEAHQLTKEAFNaLLKTL-EEppAHAIFILATTEahKVPATI------VSRV-QQFTFKKLAITDIvkklQKIVEAEKIK 176
Cdd:COG2842  129 DEADHLKPKALE-ELRDIhDE--TGVGVVLIGME--RLPAKLkryeqlYSRIgFWVEFKPLSLEDV----RALAEAWGEL 199
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 818621560 177 INDDALRLVASYADGSYRDAE----SMLEQLRIWNENMITKEDIEE 218
Cdd:COG2842  200 TDPDLLELLHRITRGNLRRLDrtlrLAARAAKRNGLTKITLDHVRA 245
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
38-133 1.07e-06

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 47.75  E-value: 1.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560    38 NHAYLFSGPRGTGKTTIARLLAKSVGCSNLDLLEIDAASNRGIDEIRQLRDGIKFAPTAG----------------KYKV 101
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASGsgelrlrlalalarklKPDV 81
                           90       100       110
                   ....*....|....*....|....*....|..
gi 818621560   102 FIIDEAHQLTKEAFNALLKTLEEPPAHAIFIL 133
Cdd:smart00382  82 LILDEITSLLDAEQEALLLLLEELRLLLLLKS 113
RuvB_N pfam05496
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ...
11-63 1.61e-06

Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.


Pssm-ID: 398900 [Multi-domain]  Cd Length: 159  Bit Score: 47.49  E-value: 1.61e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 818621560   11 RPQSWEEIIGQEHIVRTLTNALKLGR-----VNHAyLFSGPRGTGKTTIARLLAKSVG 63
Cdd:pfam05496   2 RPRTLDEYIGQEKVKENLKIFIEAAKqrgeaLDHV-LLYGPPGLGKTTLANIIANEMG 58
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
12-136 2.11e-06

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 46.89  E-value: 2.11e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  12 PQSWEEIIGQEHIVRTLTNALKLGRVNhaYLFSGPRGTGKTTIARLLAKSvgcSNLDLLEIDAAS--NRGIDE-IRQLRD 88
Cdd:cd19481    2 KASLREAVEAPRRGSRLRRYGLGLPKG--ILLYGPPGTGKTLLAKALAGE---LGLPLIVVKLSSllSKYVGEsEKNLRK 76
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 818621560  89 GIKFAPTAGKyKVFIIDEAHQL------------TKEAFNALLKTLEEPPAHA-IFILATT 136
Cdd:cd19481   77 IFERARRLAP-CILFIDEIDAIgrkrdssgesgeLRRVLNQLLTELDGVNSRSkVLVIAAT 136
MoxR COG0714
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ...
18-65 3.66e-06

MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 440478 [Multi-domain]  Cd Length: 292  Bit Score: 47.85  E-value: 3.66e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 818621560  18 IIGQEHIVRTLTNALKLGRvnHAyLFSGPRGTGKTTIARLLAKSVGCS 65
Cdd:COG0714   14 YVGQEELIELVLIALLAGG--HL-LLEGVPGVGKTTLAKALARALGLP 58
RuvB COG2255
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ...
11-63 3.92e-06

Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];


Pssm-ID: 441856 [Multi-domain]  Cd Length: 337  Bit Score: 48.15  E-value: 3.92e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 818621560  11 RPQSWEEIIGQEHIVRTL----TNALKLGRV-NHAyLFSGPRGTGKTTIARLLAKSVG 63
Cdd:COG2255   23 RPKRLDEYIGQEKVKENLkifiEAAKKRGEAlDHV-LLYGPPGLGKTTLAHIIANEMG 79
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
75-148 5.71e-06

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 47.15  E-value: 5.71e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 818621560  75 ASNRGIDEIRQLRDGIKFAPTAGKYKVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSR 148
Cdd:PRK06581  66 AKNISIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAASIISTIRSR 139
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
100-178 6.65e-06

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 46.75  E-value: 6.65e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 818621560 100 KVFIIDEAHQLTKEAFNALLKTLEEPPAHAIFILATTEAHKVPATIVSRVQQFTFKKLAITDIVKKLQKIVEAEKIKIN 178
Cdd:PRK05818  90 KIYIIYGIEKLNKQSANSLLKLIEEPPKNTYGIFTTRNENNILNTILSRCVQYVVLSKEKKVPFKVESNDRYFQYILLS 168
DNA_pol3_gamma3 pfam12169
DNA polymerase III subunits gamma and tau domain III; This domain family is found in bacteria, ...
211-340 9.17e-06

DNA polymerase III subunits gamma and tau domain III; This domain family is found in bacteria, and is approximately 110 amino acids in length. The family is found in association with pfam00004. Domains I-III are shared between the tau and the gamma subunits, while most of the DnaB-binding Domain IV and all of the alpha-interacting Domain V are unique to tau.


Pssm-ID: 432379 [Multi-domain]  Cd Length: 143  Bit Score: 44.95  E-value: 9.17e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  211 ITKEDIEELLGAIDFEKVRVLSDHLQDSNAKGAIDYIGKLIEAGVDLEVFAKAFINHLRKIMLIKV--DSSLVDLMSQEl 288
Cdd:pfam12169   1 VTAAQVRDMLGLADRGRVLDLLEALLEGDAAAALAELRDQYDAGADPVVVLRDLLELIHNLTRLKVapDAADDLLLPEE- 79
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 818621560  289 tvdQVEIVKKQAESFSLNNVAQAIKIFTNARNDIKRSPIPSLPIELAVVEII 340
Cdd:pfam12169  80 ---ERARLAELAEKLSPEVLHRLWQMLLKGIEEVPNAPDPRQAAEMVLLRLA 128
AAA_5 pfam07728
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ...
45-124 1.51e-05

AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400191 [Multi-domain]  Cd Length: 135  Bit Score: 44.21  E-value: 1.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   45 GPRGTGKTTIARLLAKSVGCSNLDLLEIDAASNRgiDEIRQLRD----GIKFAP----TAGKYK-VFIIDEAHQLTKEAF 115
Cdd:pfam07728   6 GPPGTGKTELAERLAAALSNRPVFYVQLTRDTTE--EDLFGRRNidpgGASWVDgplvRAAREGeIAVLDEINRANPDVL 83

                  ....*....
gi 818621560  116 NALLKTLEE 124
Cdd:pfam07728  84 NSLLSLLDE 92
ExeA COG3267
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ...
42-118 2.02e-05

Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442498 [Multi-domain]  Cd Length: 261  Bit Score: 45.55  E-value: 2.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  42 LFSGPRGTGKTTIARLLAKSVG-------CSN------------LDLLEIDAASNRGIDEIRQLRDGIKFAPTAGKYKVF 102
Cdd:COG3267   47 VLTGEVGTGKTTLLRRLLERLPddvkvayIPNpqlspaellraiADELGLEPKGASKADLLRQLQEFLLELAAAGRRVVL 126
                         90
                 ....*....|....*.
gi 818621560 103 IIDEAHQLTKEAFNAL 118
Cdd:COG3267  127 IIDEAQNLPPETLEEL 142
AAA_14 pfam13173
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
38-132 3.86e-05

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 463799 [Multi-domain]  Cd Length: 128  Bit Score: 42.57  E-value: 3.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560   38 NHAYLFSGPRGTGKTTIARLLAKSVGCS------NLDLLEIDAASNRGIDEIrqLRDGIKfaptaGKYKVFIIDEAhQLT 111
Cdd:pfam13173   2 RKILVITGPRQVGKTTLLLQLIKELLPPenilyiNLDDPRLLKLADFELLEL--FLELLY-----PGKTYLFLDEI-QRV 73
                          90       100
                  ....*....|....*....|.
gi 818621560  112 KEAFNALLKTLEEPPAHAIFI 132
Cdd:pfam13173  74 PDWELALKRLYDDGPNGRVIL 94
RecA-like_ClpB_Hsp104-like cd19499
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ...
16-73 3.88e-05

Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410907 [Multi-domain]  Cd Length: 178  Bit Score: 43.71  E-value: 3.88e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 818621560  16 EEIIGQEHIVRTLTNALKLGRVNHA--------YLFSGPRGTGKTTIARLLAKSVGCSNLDLLEID 73
Cdd:cd19499   11 ERVVGQDEAVKAVSDAIRRARAGLSdpnrpigsFLFLGPTGVGKTELAKALAELLFGDEDNLIRID 76
COG1373 COG1373
Predicted ATPase, AAA+ superfamily [General function prediction only];
22-118 5.05e-05

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440984 [Multi-domain]  Cd Length: 405  Bit Score: 44.55  E-value: 5.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  22 EHIVRTLTNAL-KLGRVNHAYLFSGPRGTGKTTIARLLAKSVGCS---NLDLLEIDAASNRGIDEIRQLrdgikFAPTAG 97
Cdd:COG1373    3 IMIKRKILDKLlKLLDNRKAVVITGPRQVGKTTLLKQLAKELENIlyiNLDDPRLRALAEEDPDDLLEA-----LKELYP 77
                         90       100
                 ....*....|....*....|.
gi 818621560  98 KYKVFIIDEAhQLTKEAFNAL 118
Cdd:COG1373   78 GKTYLFLDEI-QRVPEWEDAL 97
clpC CHL00095
Clp protease ATP binding subunit
16-124 6.74e-05

Clp protease ATP binding subunit


Pssm-ID: 214361 [Multi-domain]  Cd Length: 821  Bit Score: 44.66  E-value: 6.74e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  16 EEIIGQEHIVRTLTNALKLGRVN--------HAYLFSGPRGTGKTTIARLLAKSVGCSNLDLLEIDAASNR--------- 78
Cdd:CHL00095 509 KRIIGQDEAVVAVSKAIRRARVGlknpnrpiASFLFSGPTGVGKTELTKALASYFFGSEDAMIRLDMSEYMekhtvskli 588
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 818621560  79 -------GIDEIRQLRDGIKFAPtagkYKVFIIDEAHQLTKEAFNALLKTLEE 124
Cdd:CHL00095 589 gsppgyvGYNEGGQLTEAVRKKP----YTVVLFDEIEKAHPDIFNLLLQILDD 637
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
45-83 1.11e-04

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 41.77  E-value: 1.11e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 818621560  45 GPRGTGKTTIARLLAKSVGCSNLDL-LEIDAASNRGIDEI 83
Cdd:cd00464    6 GMMGAGKTTVGRLLAKALGLPFVDLdELIEQRAGMSIPEI 45
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
45-83 1.74e-04

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 41.65  E-value: 1.74e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 818621560  45 GPRGTGKTTIARLLAKSVGCSNLDL-LEIDAASNRGIDEI 83
Cdd:COG0703    5 GMMGAGKSTVGRLLAKRLGLPFVDTdAEIEERAGMSIPEI 44
HLD_clamp cd18133
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ...
162-220 2.64e-04

helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.


Pssm-ID: 350838 [Multi-domain]  Cd Length: 65  Bit Score: 38.61  E-value: 2.64e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 162 IVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLR-IWNENMITKEDIEELL 220
Cdd:cd18133    6 LKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAaLGDDGKISLDRVYQAV 65
HLD_clamp_RFC cd18140
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ...
160-219 2.91e-04

helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.


Pssm-ID: 350842 [Multi-domain]  Cd Length: 63  Bit Score: 38.66  E-value: 2.91e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 160 TDIVKKLQKIVEAEKIKINDDALRLVASYADGSYRDAESMLEQLRIWNENmITKEDIEEL 219
Cdd:cd18140    4 EQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQAAAAGGGV-ITEEDVYEV 62
aroK PRK00131
shikimate kinase; Reviewed
45-83 1.68e-03

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 38.63  E-value: 1.68e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 818621560  45 GPRGTGKTTIARLLAKSVGCSNLDL-LEIDAASNRGIDEI 83
Cdd:PRK00131  11 GFMGAGKSTIGRLLAKRLGYDFIDTdHLIEARAGKSIPEI 50
AAA_16 pfam13191
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
17-86 1.78e-03

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433025 [Multi-domain]  Cd Length: 167  Bit Score: 38.64  E-value: 1.78e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 818621560   17 EIIGQEHIVRTLTNALK---LGRVNHAYLfSGPRGTGKTTIARLLAKSVGCSNLDLLEIDAASNRGIDEIRQL 86
Cdd:pfam13191   1 RLVGREEELEQLLDALDrvrSGRPPSVLL-TGEAGTGKTTLLRELLRALERDGGYFLRGKCDENLPYSPLLEA 72
TIP49 COG1224
DNA helicase TIP49, TBP-interacting protein [Transcription];
101-218 3.15e-03

DNA helicase TIP49, TBP-interacting protein [Transcription];


Pssm-ID: 440837 [Multi-domain]  Cd Length: 452  Bit Score: 39.18  E-value: 3.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 101 VFIIDEAHQLTKEAFNALLKTLEEPPAhAIFILATT-----------EA-HKVPATIVSRVqqftfkkLAIT------DI 162
Cdd:COG1224  295 VLFIDDAHMLDIEAFSFLTRAMESELA-PIIILATNrgitkirgtdiESpHGIPLDLLDRL-------LIIPtrpyteDE 366
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 818621560 163 VKKLQKI-VEAEKIKINDDAL-RLVASYADGSYRDAESMLEQLRIW----NENMITKEDIEE 218
Cdd:COG1224  367 IREIIKIrAEEEDIELSDDALeELTKIGVERSLRYAVQLLEPAYIIakrrGRSKVTVEDVEE 428
Mg_chelatase pfam01078
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ...
15-58 3.58e-03

Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.


Pssm-ID: 426032 [Multi-domain]  Cd Length: 207  Bit Score: 38.29  E-value: 3.58e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 818621560   15 WEEIIGQEHIVRTLTNALKLGrvnHAYLFSGPRGTGKTTIARLL 58
Cdd:pfam01078   2 LADVKGQEQAKRALEIAAAGG---HNLLMIGPPGSGKTMLAKRL 42
clpA PRK11034
ATP-dependent Clp protease ATP-binding subunit; Provisional
18-123 7.86e-03

ATP-dependent Clp protease ATP-binding subunit; Provisional


Pssm-ID: 236828 [Multi-domain]  Cd Length: 758  Bit Score: 38.28  E-value: 7.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  18 IIGQEHIVRTLTNALKLGRVN--------HAYLFSGPRGTGKTTIARLLAKSVGcsnLDLLEIDAAS-------NR---- 78
Cdd:PRK11034 460 VFGQDKAIEALTEAIKMSRAGlghehkpvGSFLFAGPTGVGKTEVTVQLSKALG---IELLRFDMSEymerhtvSRliga 536
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 818621560  79 -----GIDEIRQLRDGIKFAPTAgkykVFIIDEAHQLTKEAFNALLKTLE 123
Cdd:PRK11034 537 ppgyvGFDQGGLLTDAVIKHPHA----VLLLDEIEKAHPDVFNLLLQVMD 582
CDC6 COG1474
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
16-234 8.02e-03

Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];


Pssm-ID: 441083 [Multi-domain]  Cd Length: 389  Bit Score: 37.91  E-value: 8.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  16 EEIigqEHIVRTLTNALKLGRVNHAYLFsGPRGTGKTTIARLLAK------SVGCSNLDLLEIDAASNRGIDEI-----R 84
Cdd:COG1474   33 EEI---EELASALRPALRGERPSNVLIY-GPTGTGKTAVAKYVLEeleeeaEERGVDVRVVYVNCRQASTRYRVlsrilE 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560  85 QLRDGIKFAPT-----------------AGKYKVFIIDEAHQLTKEAFNALLKTL----EEPPAHAIFILATTEAHKVPA 143
Cdd:COG1474  109 ELGSGEDIPSTglstdelfdrlyealdeRDGVLVVVLDEIDYLVDDEGDDLLYQLlranEELEGARVGVIGISNDLEFLE 188
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818621560 144 TIVSRVQqftfKKLAITDIV------KKLQKIVE--AEKI----KINDDALRLVASYA---DGSYRDAesmLEQLRI--- 205
Cdd:COG1474  189 NLDPRVK----SSLGEEEIVfppydaDELRDILEdrAELAfydgVLSDEVIPLIAALAaqeHGDARKA---IDLLRVage 261
                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 818621560 206 ----WNENMITKEDIEELLGAIDF----EKVRVLSDH 234
Cdd:COG1474  262 iaerEGSDRVTEEHVREAREKIERdrllEVLRGLPTH 298
HLD_clamp_RarA cd18139
helical lid domain of recombination factor protein RarA; Recombination factor RarA ...
157-221 8.86e-03

helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.


Pssm-ID: 350841 [Multi-domain]  Cd Length: 75  Bit Score: 34.53  E-value: 8.86e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 818621560 157 LAITDIVKKLQKIVEAE------KIKINDDALRLVASYADGSYRDAESMLEQLRIWNENM----ITKEDIEELLG 221
Cdd:cd18139    1 LSEEDLEKLLKRALEDKerggdrKVTIDDEALELLAEAADGDARSALNLLELAVLSAEEDggivITLEDLEEVLQ 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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