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Conserved domains on  [gi|818614977|gb|KKS63562|]
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Recombination regulator RecX [candidate division WWE3 bacterium GW2011_GWF1_42_51]

Protein Classification

regulatory protein RecX( domain architecture ID 10005398)

regulatory protein RecX modulates RecA activities (both recombinase and coprotease) through direct physical interaction

CATH:  1.10.10.10
Gene Ontology:  GO:0006282
PubMed:  18650935

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
5-166 4.61e-23

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 89.08  E-value: 4.61e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818614977   5 RESVDKLYSKILDFVSYSFRTEKEVRDraayYLRKISFPPgvdpaTVVDEIILRFKTSRDIDDDEYTRRYIEGLILSpKS 84
Cdd:COG2137    2 EDTEKKARNRALRLLARRERSRKELRR----KLARKGFDE-----EEIEEVLDRLKEEGYLDDERFAESYVRSRLRR-KG 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818614977  85 KSSREAAMFLYKKGIPESISGKYLSQLGGELEEKSLGILVEKKARSLKSLRDPATRNKLIRYLISKGFNPDRVRAEVDKI 164
Cdd:COG2137   72 YGPRRIRQELRQKGIDEELIEEALEELDEEDELEAARELARKKFGSLKPLDPAKEKQKLARFLARRGFSSDLIRRVLREL 151

                 ..
gi 818614977 165 AS 166
Cdd:COG2137  152 LE 153
 
Name Accession Description Interval E-value
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
5-166 4.61e-23

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 89.08  E-value: 4.61e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818614977   5 RESVDKLYSKILDFVSYSFRTEKEVRDraayYLRKISFPPgvdpaTVVDEIILRFKTSRDIDDDEYTRRYIEGLILSpKS 84
Cdd:COG2137    2 EDTEKKARNRALRLLARRERSRKELRR----KLARKGFDE-----EEIEEVLDRLKEEGYLDDERFAESYVRSRLRR-KG 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818614977  85 KSSREAAMFLYKKGIPESISGKYLSQLGGELEEKSLGILVEKKARSLKSLRDPATRNKLIRYLISKGFNPDRVRAEVDKI 164
Cdd:COG2137   72 YGPRRIRQELRQKGIDEELIEEALEELDEEDELEAARELARKKFGSLKPLDPAKEKQKLARFLARRGFSSDLIRRVLREL 151

                 ..
gi 818614977 165 AS 166
Cdd:COG2137  152 LE 153
recX PRK14135
recombination regulator RecX; Provisional
1-153 1.84e-12

recombination regulator RecX; Provisional


Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 63.31  E-value: 1.84e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818614977   1 MSDIR--ESVDKLYSKILDFVSYSFRTEKEVRDraayYLRKISFPPgvdpaTVVDEIILRFKTSRDIDDDEYTRRYIEGL 78
Cdd:PRK14135  47 LEEIQyaDQVSKGKNLALYYLSYQMRTEKEVRD----YLKKHEISE-----EIISEVIDKLKEEKYIDDKEYAESYVRTN 117
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 818614977  79 ILSpKSKSSREAAMFLYKKGIPESISGKYLSQLGGELEEKSLGILVEKKARSLKSLRDPATRNKLIRYLISKGFN 153
Cdd:PRK14135 118 INT-GDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIEVAQKLAEKLLKKYQKLPFKALKQKIIQSLLTKGFS 191
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
37-166 2.54e-12

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 60.29  E-value: 2.54e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818614977   37 LRKISFPPgvdpaTVVDEIILRFKTSRDIDDDEYTRRYIEGLILSpKSKSSREAAMFLYKKGIPESISGKYLSQLggELE 116
Cdd:pfam02631   1 LRKKGFSE-----EVIEEVLDRLKELGYLDDARFAESFVRSRART-RGKGPRRIRQELRQKGVDEEIIEEALEEF--DEE 72
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 818614977  117 EKSLGILVEKKARSLKSLRDPATRNKLIRYLISKGFNPDRVRAEVDKIAS 166
Cdd:pfam02631  73 EQIARELAEKKFKRYPAESDRKLKQKLIRFLARRGFSSEVIRAALQEEDE 122
 
Name Accession Description Interval E-value
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
5-166 4.61e-23

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 89.08  E-value: 4.61e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818614977   5 RESVDKLYSKILDFVSYSFRTEKEVRDraayYLRKISFPPgvdpaTVVDEIILRFKTSRDIDDDEYTRRYIEGLILSpKS 84
Cdd:COG2137    2 EDTEKKARNRALRLLARRERSRKELRR----KLARKGFDE-----EEIEEVLDRLKEEGYLDDERFAESYVRSRLRR-KG 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818614977  85 KSSREAAMFLYKKGIPESISGKYLSQLGGELEEKSLGILVEKKARSLKSLRDPATRNKLIRYLISKGFNPDRVRAEVDKI 164
Cdd:COG2137   72 YGPRRIRQELRQKGIDEELIEEALEELDEEDELEAARELARKKFGSLKPLDPAKEKQKLARFLARRGFSSDLIRRVLREL 151

                 ..
gi 818614977 165 AS 166
Cdd:COG2137  152 LE 153
recX PRK14135
recombination regulator RecX; Provisional
1-153 1.84e-12

recombination regulator RecX; Provisional


Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 63.31  E-value: 1.84e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818614977   1 MSDIR--ESVDKLYSKILDFVSYSFRTEKEVRDraayYLRKISFPPgvdpaTVVDEIILRFKTSRDIDDDEYTRRYIEGL 78
Cdd:PRK14135  47 LEEIQyaDQVSKGKNLALYYLSYQMRTEKEVRD----YLKKHEISE-----EIISEVIDKLKEEKYIDDKEYAESYVRTN 117
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 818614977  79 ILSpKSKSSREAAMFLYKKGIPESISGKYLSQLGGELEEKSLGILVEKKARSLKSLRDPATRNKLIRYLISKGFN 153
Cdd:PRK14135 118 INT-GDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIEVAQKLAEKLLKKYQKLPFKALKQKIIQSLLTKGFS 191
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
37-166 2.54e-12

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 60.29  E-value: 2.54e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818614977   37 LRKISFPPgvdpaTVVDEIILRFKTSRDIDDDEYTRRYIEGLILSpKSKSSREAAMFLYKKGIPESISGKYLSQLggELE 116
Cdd:pfam02631   1 LRKKGFSE-----EVIEEVLDRLKELGYLDDARFAESFVRSRART-RGKGPRRIRQELRQKGVDEEIIEEALEEF--DEE 72
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 818614977  117 EKSLGILVEKKARSLKSLRDPATRNKLIRYLISKGFNPDRVRAEVDKIAS 166
Cdd:pfam02631  73 EQIARELAEKKFKRYPAESDRKLKQKLIRFLARRGFSSEVIRAALQEEDE 122
recX PRK00117
recombination regulator RecX; Reviewed
24-159 3.11e-08

recombination regulator RecX; Reviewed


Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 50.27  E-value: 3.11e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818614977  24 RTEKEVRDRAAYYL-----------RKISfPPGVDPAtVVDEIILRFKTSRDIDDDEYTRRYIEGLILSPKSKssREAAM 92
Cdd:PRK00117   8 RMYASARARALRLLarrehsraelrRKLA-AKGFSEE-VIEAVLDRLKEEGLLDDERFAESFVRSRARKGYGP--RRIRQ 83
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 818614977  93 FLYKKGIPESISGKYLSQLGGELEEKSLGiLVEKKARSLKsLRDPATRNKLIRYLISKGFNPDRVRA 159
Cdd:PRK00117  84 ELRQKGVDREIIEEALAELDIDWEELARE-LARKKFRRPL-PDDAKEKAKLVRFLARRGFSMDVIQR 148
recX PRK14134
recombination regulator RecX; Provisional
16-166 3.30e-07

recombination regulator RecX; Provisional


Pssm-ID: 184530 [Multi-domain]  Cd Length: 283  Bit Score: 48.65  E-value: 3.30e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818614977  16 LDFVSYSFRTEKEVRDRaayyLRKISFPPGVdpatvVDEIILRFKTSRDIDDDEYTRRYIEGLILSPKSKSSREAamfLY 95
Cdd:PRK14134  68 LKYIEKSYKTEKQIKEK----LYLKEYDEDA-----VNRVIRFLKEYNFIDDDKYCDMYIREKINSYGRNKIKYT---LL 135
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 818614977  96 KKGIPESISGKYLSQLGGELEEKSLGILVEKKARSLKSLRDPATR--NKLIRYLISKGFNPDRVRAEVDKIAS 166
Cdd:PRK14134 136 NKGIKENIIIEKINNIDEEKEKKVAYKLAEKKYKILILSEKNKFKiyKKLGPYLISRGYSSNIAEWILNELIK 208
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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