YhjD family protein similar to Escherichia coli inner membrane protein YhjD; related to Bordetella pertussis BrkB, a virulence factor that is essential for resistance to complement-dependent killing by serum
inner membrane protein YhjD; This family, including YhjD in E. coli, is a conserved inner ...
56-330
5.86e-136
inner membrane protein YhjD; This family, including YhjD in E. coli, is a conserved inner membrane protein homologous YihY, which in turn was incorrectly assigned to be ribonuclease BN. This, any suggestion this family is similar to ribonucleases should be removed. [Transcription, Degradation of RNA]
:
Pssm-ID: 188082 Cd Length: 263 Bit Score: 386.95 E-value: 5.86e-136
inner membrane protein YhjD; This family, including YhjD in E. coli, is a conserved inner ...
56-330
5.86e-136
inner membrane protein YhjD; This family, including YhjD in E. coli, is a conserved inner membrane protein homologous YihY, which in turn was incorrectly assigned to be ribonuclease BN. This, any suggestion this family is similar to ribonucleases should be removed. [Transcription, Degradation of RNA]
Pssm-ID: 188082 Cd Length: 263 Bit Score: 386.95 E-value: 5.86e-136
Virulence factor BrkB; This family acts as a virulence factor. In Bordetella pertussis, Swiss: ...
70-331
1.18e-40
Virulence factor BrkB; This family acts as a virulence factor. In Bordetella pertussis, Swiss:Q45339 is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.
Pssm-ID: 460996 Cd Length: 256 Bit Score: 143.15 E-value: 1.18e-40
inner membrane protein YhjD; This family, including YhjD in E. coli, is a conserved inner ...
56-330
5.86e-136
inner membrane protein YhjD; This family, including YhjD in E. coli, is a conserved inner membrane protein homologous YihY, which in turn was incorrectly assigned to be ribonuclease BN. This, any suggestion this family is similar to ribonucleases should be removed. [Transcription, Degradation of RNA]
Pssm-ID: 188082 Cd Length: 263 Bit Score: 386.95 E-value: 5.86e-136
Virulence factor BrkB; This family acts as a virulence factor. In Bordetella pertussis, Swiss: ...
70-331
1.18e-40
Virulence factor BrkB; This family acts as a virulence factor. In Bordetella pertussis, Swiss:Q45339 is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.
Pssm-ID: 460996 Cd Length: 256 Bit Score: 143.15 E-value: 1.18e-40
YihY family inner membrane protein; Initial identification of members of this protein family ...
64-286
9.93e-07
YihY family inner membrane protein; Initial identification of members of this protein family was based on characterization of the yihY gene product as ribonuclease BN in Escherichia coli. This identification has been withdrawn, as the group now finds the homolog in E. coli of RNase Z is the true ribonuclease BN rather than a strict functional equivalent of RNase Z. Members of this subfamily include the largely uncharacterized BrkB (Bordetella resist killing by serum B) from Bordetella pertussis. Some members have an additional C-terminal domain. Paralogs from E. coli (yhjD) and Mycobactrium tuberculosis (Rv3335c) are part of a smaller, related subfamily that form their own cluster. [Unknown function, General]
Pssm-ID: 273260 Cd Length: 259 Bit Score: 49.29 E-value: 9.93e-07
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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