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Conserved domains on  [gi|757946705|gb|KIS69173|]
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hypothetical protein UMAG_02524 [Mycosarcoma maydis]

Protein Classification

nuclear pore complex Nup192/Nup205 family protein( domain architecture ID 10571003)

nuclear pore complex Nup192/Nup205 family protein; similar to Homo sapiens Nup205 and Saccharomyces cerevisiae Nup192, which are components (nucleoporins, NUPs) of the nuclear pore complex (NPC) that can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Nup192 pfam11894
Nuclear pore complex scaffold, nucleoporins 186/192/205; This is a family of eukaryotic ...
 198-1971 0e+00

Nuclear pore complex scaffold, nucleoporins 186/192/205; This is a family of eukaryotic nucleoporins of several different sizes. All of them are long and form the scaffold of the nuclear pore complex. Nup192 in particular modulates the permeability of the central channel of the NPC central or nuclear pore complex.


:

Pssm-ID: 463387  Cd Length: 1484  Bit Score: 862.72  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   198 TLAERILAEIDNVKQSTAHVKASLESpgSNIANQGiqtQTSNFFGlgssqtakqpsststasggrlSDEIQLDRLgwlRE 277
Cdd:pfam11894    6 TLVTNILDSFKEIHGLLQRLLDLVNK--ADILGEI---QDNRFLG---------------------TIKFRRDSL---FK 56

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   278 ERRELGHLLYLLSISSLLTTSNILAILRWLAavSAETYDEMTIYVLTALLGAIDATpdaRAAMADRASRGTLRNTVEALL 357
Cdd:pfam11894   57 EHELLAQILFGLVAQRGLPKDDFLKLIDHAK--KADKYDFLTLHYLPALLAAFGSL---EDLSVLQDVRELHSKITKSLD 131

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   358 DDESFITVthaeitrkhwalgELNSAVALQWSIFLVEAFSRNPTYRTQLSISEEQIQDLVLQSITGsslskdskatsgee 437
Cdd:pfam11894  132 SEWPLYTD-------------GLKAAIIFVFLAEFIGWCKQEPEERAKQFDFKEDIEKPMDEALED-------------- 184

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   438 gptgGAFIFLVVRVLAFRQK--------TIDALFGEEEGALTAEADTaagdvidinawedeVDAEFREYVVQQIHNLALG 509
Cdd:pfam11894  185 ----GAFEFLLSIAADTSNKdwedplryDFRSLLQRHIPRLTPEKLL--------------LSDYFEEFLLRQLHTFITD 246

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   510 TTSVMLPMLRRIQRSEEDAAFALSRAVSargstsappERRYDIEALFDLIALLCRGRPEAGLPFWVGSDNRPTRFLAWAI 589
Cdd:pfam11894  247 FISNMADVLTKLRDREEDSLLSQESLLQ---------EGRADLERFLLIIAYLYEGRPDLALEFWSDRESNLYGFIEWAS 317

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   590 DVREPGHQRALLNMLAAMSSGPQSASQAYALLDQESSQaGATGEGRLVSWSRFFEWITYYIDTFHQ-----AVNTSSFHA 664
Cdd:pfam11894  318 SRLPSPLISAFCLMLSSLSSGEENARAAFNFLKDNNNS-GKKRRSSSVSWDHIFDSLNYYIDKLRQkpenfESDGDRQQR 396

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   665 SSYQTLAMPKNEETLLIGFVRLFRNVVYFSHPARDALLQNSSYNALDKLFTLLTCPIPVELKASILDALSAFLHLSlsnp 744
Cdd:pfam11894  397 QEAIPIELEPESIIFLSSYLRLISSVAKNSEEARLALLEHPSWRFLDVLFGLLSCKVPTPLKAAILNTLSALVKKS---- 472

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   745 aaqarfSSIATQLWDRFDecglipsddaaARSRLNSNTNASGSFGPAFKPlasRGVLYELENFEVPLRTFPGSTSFVNFL 824
Cdd:pfam11894  473 ------EEEAYQIWRSLD-----------RWIFGGSQLLPTVPRTSSYKP---RGSYSELEAFESRLEGYPEVRAFLQLL 532

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   825 KALVQLPSGTlaagSNALTDAPLTSATNANPfstivsydqqaqqqiqgstqpvyqqqqrrQTRSVEPYVDFVIDHVFLKa 904
Cdd:pfam11894  533 KALLSPPEDS----SSLFGKLPFPENLGAGY-----------------------------RKPGIWPYLDFVLDEVFLK- 578

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   905 RTRDYVEPAEQWRVVASCLDFVERSLRSYDLAALLRSSERA---DAVTDPALLTQLASHPGFFLMRRILTGSKMVGEMLG 981
Cdd:pfam11894  579 STRDYKDPAEKWELQLSCLEFIETCLRSFDPSLILFSNPSGinlDSLVSTSDFATYVKLHPFHAVLNYLFNEKVLKALFS 658

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   982 ILVPGSglgafEAINqNRASTFFYGTSVRHVLSILDRVLRYQDLFVQVLIPTLVdttlngVQLPFDVSTRVGNSGsYSSF 1061
Cdd:pfam11894  659 IIDEGV-----DELD-NYLGKSPLELLVLLALEIIDKVLDLQETYLDELLPILK------KSQNIYRPKNVGNHG-LSSF 725

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1062 DVQLLHAHESVVQIALLINCVRDDVALLSVRLLGLIARTAAFSAvdrfGEMGYRRKMNRLVGLLEMSDEASRVRAGYVAR 1141
Cdd:pfam11894  726 YDALLFNLSLVLNLGLYVGYGHPELALASLKILEKISSSPKFSA----SSAGRLLHRNKLLTIFESVDESERIKRGFIEQ 801

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1142 LEAESSGDAgsakmleslnglagglqsDEDEDADLQasngrldgitalassdaveaIQIAIVNLLLAGTELNQPAPNVAH 1221
Cdd:pfam11894  802 LEAPIDEEE------------------QGAESIGLQ--------------------IKEAILDFLNSNLSASPKRPTIAH 843

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1222 LLLGYDLRavrpeEQVIVDPDAQT---TAPSAIHVILALLR--PESDGDGAsflSLAERSPSFAEKCFSLILRLCTHPFT 1296
Cdd:pfam11894  844 FLLGFDVR-----NDLSLGPDQSTfiaSPRSLLHSLLLLLLssLDLISEGD---YIDYAPARLAELILEILYKLCRNPLT 915

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1297 SAATLRYLRTKEDyVVQQLRSISLVpaergaLTESSAALGLVQFADGQAIETTIDRVTASLRMRASLLELTALELHSLLN 1376
Cdd:pfam11894  916 SSITLRYLRENCF-LFRHLLSLPPK------IDPNTLWNGQSFDGVFFISSPSAGALLSFLNQRSLLLQYLSLELHSTSQ 988

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1377 AGMQSRAARVVAALFGSNATAGGGngidadgsidedelllgterdfrlgaggaeirSFGGVRLLEILQSLDFEWHD---- 1452
Cdd:pfam11894  989 SGSPSKKKRYVDLLLGNNILDGGE--------------------------------PIGSPTIFDFLDFLNFEFINfepq 1036

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1453 -DREALGQNitvITPEQLDLAKRPDAAVGPRLYDLSAVLAILVREKTILQQKGNLRDAGQANPFLEQAAFVLQWASAQNA 1531
Cdd:pfam11894 1037 pQLEFFDIK---NLSLDLDKCELDDADSGNKLYDISKLHELLRLELKQLLLVQGESKAGQEKEIMAEINKILEFATKYNR 1113

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1532 KKAVAFSRRRVLQAWRHTLDMVLarAAGLLRTEVRSGLMFDCLSELLPRISTPSTDAGALDAPSADLVAGAVLSLLTSLR 1611
Cdd:pfam11894 1114 QKQLRAAQLSFLHSWVQLVQVLV--SDGDLSSTVRSNFILEVLQAILPKINDYVELDIAFAEELASLASVLLFDLYAKLR 1191

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1612 QHRVELTTGALDletvdaLPTDRLLTTLRALIDSILRLETTTLARGNLYSALINFLQLVKSgsgadasdetgandgasiv 1691
Cdd:pfam11894 1192 QCINLDEEQKGN------LSSDRLHQLFKTCIDGILSSGSTQKLRSDLYVILNNYLQIVFK------------------- 1246

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1692 atdvddtmsvggasttitnifgGRTQTSSLEARTRTLLLSYLERLMDVLGRDALDASDLSKTIAFTLLDKLCALDappss 1771
Cdd:pfam11894 1247 ----------------------NRSSEESLRKETLQIIKSYGEKLIEVICNDAIGGEGTCRITALLLLDSLVHLD----- 1299

                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1772 gsssRRGGSRCLDLLDRKGYIKSFVTALRDSDLALQETLRPDPASLNSLY--VYEARLAFFNRMAQSRDGAERLLNAKIF 1849
Cdd:pfam11894 1300 ----SNKSNFILETLSKNNYLLLLVRSLKRTDEELRECLAPDPESLDPLYetAFESKLALLIRIAQTRLGAQQLLQNGLF 1375

                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1850 DVLAQSDYLAARPDQdQEFVDFDSFLPAATERYNAMLTPVLQLTTSILasTSAGAASQGAfgitkalsstsassaPRHAL 1929
Cdd:pfam11894 1376 SVLESCKFLAIDPDL-GLSLDNPLSLPDALERYFELLVPVLQLITAIL--LSLGSSNKSA---------------IEQVR 1437

                         1770      1780      1790      1800
                   ....*....|....*....|....*....|....*....|....*
gi 757946705  1930 ALLTAHRDTLLTVLRAPLQEFCSFAQLGQAHLV---VAIFVLIMS 1971
Cdd:pfam11894 1438 KFLKHHRDLVVGVLKRDALPESGIGYAELEEGLqelAKLFVLLAT 1482
 
Name Accession Description Interval E-value
Nup192 pfam11894
Nuclear pore complex scaffold, nucleoporins 186/192/205; This is a family of eukaryotic ...
 198-1971 0e+00

Nuclear pore complex scaffold, nucleoporins 186/192/205; This is a family of eukaryotic nucleoporins of several different sizes. All of them are long and form the scaffold of the nuclear pore complex. Nup192 in particular modulates the permeability of the central channel of the NPC central or nuclear pore complex.


Pssm-ID: 463387  Cd Length: 1484  Bit Score: 862.72  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   198 TLAERILAEIDNVKQSTAHVKASLESpgSNIANQGiqtQTSNFFGlgssqtakqpsststasggrlSDEIQLDRLgwlRE 277
Cdd:pfam11894    6 TLVTNILDSFKEIHGLLQRLLDLVNK--ADILGEI---QDNRFLG---------------------TIKFRRDSL---FK 56

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   278 ERRELGHLLYLLSISSLLTTSNILAILRWLAavSAETYDEMTIYVLTALLGAIDATpdaRAAMADRASRGTLRNTVEALL 357
Cdd:pfam11894   57 EHELLAQILFGLVAQRGLPKDDFLKLIDHAK--KADKYDFLTLHYLPALLAAFGSL---EDLSVLQDVRELHSKITKSLD 131

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   358 DDESFITVthaeitrkhwalgELNSAVALQWSIFLVEAFSRNPTYRTQLSISEEQIQDLVLQSITGsslskdskatsgee 437
Cdd:pfam11894  132 SEWPLYTD-------------GLKAAIIFVFLAEFIGWCKQEPEERAKQFDFKEDIEKPMDEALED-------------- 184

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   438 gptgGAFIFLVVRVLAFRQK--------TIDALFGEEEGALTAEADTaagdvidinawedeVDAEFREYVVQQIHNLALG 509
Cdd:pfam11894  185 ----GAFEFLLSIAADTSNKdwedplryDFRSLLQRHIPRLTPEKLL--------------LSDYFEEFLLRQLHTFITD 246

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   510 TTSVMLPMLRRIQRSEEDAAFALSRAVSargstsappERRYDIEALFDLIALLCRGRPEAGLPFWVGSDNRPTRFLAWAI 589
Cdd:pfam11894  247 FISNMADVLTKLRDREEDSLLSQESLLQ---------EGRADLERFLLIIAYLYEGRPDLALEFWSDRESNLYGFIEWAS 317

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   590 DVREPGHQRALLNMLAAMSSGPQSASQAYALLDQESSQaGATGEGRLVSWSRFFEWITYYIDTFHQ-----AVNTSSFHA 664
Cdd:pfam11894  318 SRLPSPLISAFCLMLSSLSSGEENARAAFNFLKDNNNS-GKKRRSSSVSWDHIFDSLNYYIDKLRQkpenfESDGDRQQR 396

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   665 SSYQTLAMPKNEETLLIGFVRLFRNVVYFSHPARDALLQNSSYNALDKLFTLLTCPIPVELKASILDALSAFLHLSlsnp 744
Cdd:pfam11894  397 QEAIPIELEPESIIFLSSYLRLISSVAKNSEEARLALLEHPSWRFLDVLFGLLSCKVPTPLKAAILNTLSALVKKS---- 472

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   745 aaqarfSSIATQLWDRFDecglipsddaaARSRLNSNTNASGSFGPAFKPlasRGVLYELENFEVPLRTFPGSTSFVNFL 824
Cdd:pfam11894  473 ------EEEAYQIWRSLD-----------RWIFGGSQLLPTVPRTSSYKP---RGSYSELEAFESRLEGYPEVRAFLQLL 532

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   825 KALVQLPSGTlaagSNALTDAPLTSATNANPfstivsydqqaqqqiqgstqpvyqqqqrrQTRSVEPYVDFVIDHVFLKa 904
Cdd:pfam11894  533 KALLSPPEDS----SSLFGKLPFPENLGAGY-----------------------------RKPGIWPYLDFVLDEVFLK- 578

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   905 RTRDYVEPAEQWRVVASCLDFVERSLRSYDLAALLRSSERA---DAVTDPALLTQLASHPGFFLMRRILTGSKMVGEMLG 981
Cdd:pfam11894  579 STRDYKDPAEKWELQLSCLEFIETCLRSFDPSLILFSNPSGinlDSLVSTSDFATYVKLHPFHAVLNYLFNEKVLKALFS 658

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   982 ILVPGSglgafEAINqNRASTFFYGTSVRHVLSILDRVLRYQDLFVQVLIPTLVdttlngVQLPFDVSTRVGNSGsYSSF 1061
Cdd:pfam11894  659 IIDEGV-----DELD-NYLGKSPLELLVLLALEIIDKVLDLQETYLDELLPILK------KSQNIYRPKNVGNHG-LSSF 725

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1062 DVQLLHAHESVVQIALLINCVRDDVALLSVRLLGLIARTAAFSAvdrfGEMGYRRKMNRLVGLLEMSDEASRVRAGYVAR 1141
Cdd:pfam11894  726 YDALLFNLSLVLNLGLYVGYGHPELALASLKILEKISSSPKFSA----SSAGRLLHRNKLLTIFESVDESERIKRGFIEQ 801

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1142 LEAESSGDAgsakmleslnglagglqsDEDEDADLQasngrldgitalassdaveaIQIAIVNLLLAGTELNQPAPNVAH 1221
Cdd:pfam11894  802 LEAPIDEEE------------------QGAESIGLQ--------------------IKEAILDFLNSNLSASPKRPTIAH 843

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1222 LLLGYDLRavrpeEQVIVDPDAQT---TAPSAIHVILALLR--PESDGDGAsflSLAERSPSFAEKCFSLILRLCTHPFT 1296
Cdd:pfam11894  844 FLLGFDVR-----NDLSLGPDQSTfiaSPRSLLHSLLLLLLssLDLISEGD---YIDYAPARLAELILEILYKLCRNPLT 915

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1297 SAATLRYLRTKEDyVVQQLRSISLVpaergaLTESSAALGLVQFADGQAIETTIDRVTASLRMRASLLELTALELHSLLN 1376
Cdd:pfam11894  916 SSITLRYLRENCF-LFRHLLSLPPK------IDPNTLWNGQSFDGVFFISSPSAGALLSFLNQRSLLLQYLSLELHSTSQ 988

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1377 AGMQSRAARVVAALFGSNATAGGGngidadgsidedelllgterdfrlgaggaeirSFGGVRLLEILQSLDFEWHD---- 1452
Cdd:pfam11894  989 SGSPSKKKRYVDLLLGNNILDGGE--------------------------------PIGSPTIFDFLDFLNFEFINfepq 1036

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1453 -DREALGQNitvITPEQLDLAKRPDAAVGPRLYDLSAVLAILVREKTILQQKGNLRDAGQANPFLEQAAFVLQWASAQNA 1531
Cdd:pfam11894 1037 pQLEFFDIK---NLSLDLDKCELDDADSGNKLYDISKLHELLRLELKQLLLVQGESKAGQEKEIMAEINKILEFATKYNR 1113

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1532 KKAVAFSRRRVLQAWRHTLDMVLarAAGLLRTEVRSGLMFDCLSELLPRISTPSTDAGALDAPSADLVAGAVLSLLTSLR 1611
Cdd:pfam11894 1114 QKQLRAAQLSFLHSWVQLVQVLV--SDGDLSSTVRSNFILEVLQAILPKINDYVELDIAFAEELASLASVLLFDLYAKLR 1191

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1612 QHRVELTTGALDletvdaLPTDRLLTTLRALIDSILRLETTTLARGNLYSALINFLQLVKSgsgadasdetgandgasiv 1691
Cdd:pfam11894 1192 QCINLDEEQKGN------LSSDRLHQLFKTCIDGILSSGSTQKLRSDLYVILNNYLQIVFK------------------- 1246

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1692 atdvddtmsvggasttitnifgGRTQTSSLEARTRTLLLSYLERLMDVLGRDALDASDLSKTIAFTLLDKLCALDappss 1771
Cdd:pfam11894 1247 ----------------------NRSSEESLRKETLQIIKSYGEKLIEVICNDAIGGEGTCRITALLLLDSLVHLD----- 1299

                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1772 gsssRRGGSRCLDLLDRKGYIKSFVTALRDSDLALQETLRPDPASLNSLY--VYEARLAFFNRMAQSRDGAERLLNAKIF 1849
Cdd:pfam11894 1300 ----SNKSNFILETLSKNNYLLLLVRSLKRTDEELRECLAPDPESLDPLYetAFESKLALLIRIAQTRLGAQQLLQNGLF 1375

                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1850 DVLAQSDYLAARPDQdQEFVDFDSFLPAATERYNAMLTPVLQLTTSILasTSAGAASQGAfgitkalsstsassaPRHAL 1929
Cdd:pfam11894 1376 SVLESCKFLAIDPDL-GLSLDNPLSLPDALERYFELLVPVLQLITAIL--LSLGSSNKSA---------------IEQVR 1437

                         1770      1780      1790      1800
                   ....*....|....*....|....*....|....*....|....*
gi 757946705  1930 ALLTAHRDTLLTVLRAPLQEFCSFAQLGQAHLV---VAIFVLIMS 1971
Cdd:pfam11894 1438 KFLKHHRDLVVGVLKRDALPESGIGYAELEEGLqelAKLFVLLAT 1482
 
Name Accession Description Interval E-value
Nup192 pfam11894
Nuclear pore complex scaffold, nucleoporins 186/192/205; This is a family of eukaryotic ...
 198-1971 0e+00

Nuclear pore complex scaffold, nucleoporins 186/192/205; This is a family of eukaryotic nucleoporins of several different sizes. All of them are long and form the scaffold of the nuclear pore complex. Nup192 in particular modulates the permeability of the central channel of the NPC central or nuclear pore complex.


Pssm-ID: 463387  Cd Length: 1484  Bit Score: 862.72  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   198 TLAERILAEIDNVKQSTAHVKASLESpgSNIANQGiqtQTSNFFGlgssqtakqpsststasggrlSDEIQLDRLgwlRE 277
Cdd:pfam11894    6 TLVTNILDSFKEIHGLLQRLLDLVNK--ADILGEI---QDNRFLG---------------------TIKFRRDSL---FK 56

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   278 ERRELGHLLYLLSISSLLTTSNILAILRWLAavSAETYDEMTIYVLTALLGAIDATpdaRAAMADRASRGTLRNTVEALL 357
Cdd:pfam11894   57 EHELLAQILFGLVAQRGLPKDDFLKLIDHAK--KADKYDFLTLHYLPALLAAFGSL---EDLSVLQDVRELHSKITKSLD 131

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   358 DDESFITVthaeitrkhwalgELNSAVALQWSIFLVEAFSRNPTYRTQLSISEEQIQDLVLQSITGsslskdskatsgee 437
Cdd:pfam11894  132 SEWPLYTD-------------GLKAAIIFVFLAEFIGWCKQEPEERAKQFDFKEDIEKPMDEALED-------------- 184

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   438 gptgGAFIFLVVRVLAFRQK--------TIDALFGEEEGALTAEADTaagdvidinawedeVDAEFREYVVQQIHNLALG 509
Cdd:pfam11894  185 ----GAFEFLLSIAADTSNKdwedplryDFRSLLQRHIPRLTPEKLL--------------LSDYFEEFLLRQLHTFITD 246

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   510 TTSVMLPMLRRIQRSEEDAAFALSRAVSargstsappERRYDIEALFDLIALLCRGRPEAGLPFWVGSDNRPTRFLAWAI 589
Cdd:pfam11894  247 FISNMADVLTKLRDREEDSLLSQESLLQ---------EGRADLERFLLIIAYLYEGRPDLALEFWSDRESNLYGFIEWAS 317

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   590 DVREPGHQRALLNMLAAMSSGPQSASQAYALLDQESSQaGATGEGRLVSWSRFFEWITYYIDTFHQ-----AVNTSSFHA 664
Cdd:pfam11894  318 SRLPSPLISAFCLMLSSLSSGEENARAAFNFLKDNNNS-GKKRRSSSVSWDHIFDSLNYYIDKLRQkpenfESDGDRQQR 396

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   665 SSYQTLAMPKNEETLLIGFVRLFRNVVYFSHPARDALLQNSSYNALDKLFTLLTCPIPVELKASILDALSAFLHLSlsnp 744
Cdd:pfam11894  397 QEAIPIELEPESIIFLSSYLRLISSVAKNSEEARLALLEHPSWRFLDVLFGLLSCKVPTPLKAAILNTLSALVKKS---- 472

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   745 aaqarfSSIATQLWDRFDecglipsddaaARSRLNSNTNASGSFGPAFKPlasRGVLYELENFEVPLRTFPGSTSFVNFL 824
Cdd:pfam11894  473 ------EEEAYQIWRSLD-----------RWIFGGSQLLPTVPRTSSYKP---RGSYSELEAFESRLEGYPEVRAFLQLL 532

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   825 KALVQLPSGTlaagSNALTDAPLTSATNANPfstivsydqqaqqqiqgstqpvyqqqqrrQTRSVEPYVDFVIDHVFLKa 904
Cdd:pfam11894  533 KALLSPPEDS----SSLFGKLPFPENLGAGY-----------------------------RKPGIWPYLDFVLDEVFLK- 578

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   905 RTRDYVEPAEQWRVVASCLDFVERSLRSYDLAALLRSSERA---DAVTDPALLTQLASHPGFFLMRRILTGSKMVGEMLG 981
Cdd:pfam11894  579 STRDYKDPAEKWELQLSCLEFIETCLRSFDPSLILFSNPSGinlDSLVSTSDFATYVKLHPFHAVLNYLFNEKVLKALFS 658

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705   982 ILVPGSglgafEAINqNRASTFFYGTSVRHVLSILDRVLRYQDLFVQVLIPTLVdttlngVQLPFDVSTRVGNSGsYSSF 1061
Cdd:pfam11894  659 IIDEGV-----DELD-NYLGKSPLELLVLLALEIIDKVLDLQETYLDELLPILK------KSQNIYRPKNVGNHG-LSSF 725

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1062 DVQLLHAHESVVQIALLINCVRDDVALLSVRLLGLIARTAAFSAvdrfGEMGYRRKMNRLVGLLEMSDEASRVRAGYVAR 1141
Cdd:pfam11894  726 YDALLFNLSLVLNLGLYVGYGHPELALASLKILEKISSSPKFSA----SSAGRLLHRNKLLTIFESVDESERIKRGFIEQ 801

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1142 LEAESSGDAgsakmleslnglagglqsDEDEDADLQasngrldgitalassdaveaIQIAIVNLLLAGTELNQPAPNVAH 1221
Cdd:pfam11894  802 LEAPIDEEE------------------QGAESIGLQ--------------------IKEAILDFLNSNLSASPKRPTIAH 843

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1222 LLLGYDLRavrpeEQVIVDPDAQT---TAPSAIHVILALLR--PESDGDGAsflSLAERSPSFAEKCFSLILRLCTHPFT 1296
Cdd:pfam11894  844 FLLGFDVR-----NDLSLGPDQSTfiaSPRSLLHSLLLLLLssLDLISEGD---YIDYAPARLAELILEILYKLCRNPLT 915

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1297 SAATLRYLRTKEDyVVQQLRSISLVpaergaLTESSAALGLVQFADGQAIETTIDRVTASLRMRASLLELTALELHSLLN 1376
Cdd:pfam11894  916 SSITLRYLRENCF-LFRHLLSLPPK------IDPNTLWNGQSFDGVFFISSPSAGALLSFLNQRSLLLQYLSLELHSTSQ 988

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1377 AGMQSRAARVVAALFGSNATAGGGngidadgsidedelllgterdfrlgaggaeirSFGGVRLLEILQSLDFEWHD---- 1452
Cdd:pfam11894  989 SGSPSKKKRYVDLLLGNNILDGGE--------------------------------PIGSPTIFDFLDFLNFEFINfepq 1036

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1453 -DREALGQNitvITPEQLDLAKRPDAAVGPRLYDLSAVLAILVREKTILQQKGNLRDAGQANPFLEQAAFVLQWASAQNA 1531
Cdd:pfam11894 1037 pQLEFFDIK---NLSLDLDKCELDDADSGNKLYDISKLHELLRLELKQLLLVQGESKAGQEKEIMAEINKILEFATKYNR 1113

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1532 KKAVAFSRRRVLQAWRHTLDMVLarAAGLLRTEVRSGLMFDCLSELLPRISTPSTDAGALDAPSADLVAGAVLSLLTSLR 1611
Cdd:pfam11894 1114 QKQLRAAQLSFLHSWVQLVQVLV--SDGDLSSTVRSNFILEVLQAILPKINDYVELDIAFAEELASLASVLLFDLYAKLR 1191

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1612 QHRVELTTGALDletvdaLPTDRLLTTLRALIDSILRLETTTLARGNLYSALINFLQLVKSgsgadasdetgandgasiv 1691
Cdd:pfam11894 1192 QCINLDEEQKGN------LSSDRLHQLFKTCIDGILSSGSTQKLRSDLYVILNNYLQIVFK------------------- 1246

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1692 atdvddtmsvggasttitnifgGRTQTSSLEARTRTLLLSYLERLMDVLGRDALDASDLSKTIAFTLLDKLCALDappss 1771
Cdd:pfam11894 1247 ----------------------NRSSEESLRKETLQIIKSYGEKLIEVICNDAIGGEGTCRITALLLLDSLVHLD----- 1299

                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1772 gsssRRGGSRCLDLLDRKGYIKSFVTALRDSDLALQETLRPDPASLNSLY--VYEARLAFFNRMAQSRDGAERLLNAKIF 1849
Cdd:pfam11894 1300 ----SNKSNFILETLSKNNYLLLLVRSLKRTDEELRECLAPDPESLDPLYetAFESKLALLIRIAQTRLGAQQLLQNGLF 1375

                         1690      1700      1710      1720      1730      1740      1750      1760
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757946705  1850 DVLAQSDYLAARPDQdQEFVDFDSFLPAATERYNAMLTPVLQLTTSILasTSAGAASQGAfgitkalsstsassaPRHAL 1929
Cdd:pfam11894 1376 SVLESCKFLAIDPDL-GLSLDNPLSLPDALERYFELLVPVLQLITAIL--LSLGSSNKSA---------------IEQVR 1437

                         1770      1780      1790      1800
                   ....*....|....*....|....*....|....*....|....*
gi 757946705  1930 ALLTAHRDTLLTVLRAPLQEFCSFAQLGQAHLV---VAIFVLIMS 1971
Cdd:pfam11894 1438 KFLKHHRDLVVGVLKRDALPESGIGYAELEEGLqelAKLFVLLAT 1482
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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