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Conserved domains on  [gi|2277098206|gb|KAI5604421|]
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hypothetical protein BDE02_01G287900 [Populus trichocarpa]

Protein Classification

BatD family protein( domain architecture ID 1750285)

BatD family protein similar to Caenorhabditis elegans translocon-associated protein subunit beta, part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TRAP_beta super family cl47175
Translocon-associated protein beta (TRAPB); This family consists of several eukaryotic ...
 28-193 1.71e-52

Translocon-associated protein beta (TRAPB); This family consists of several eukaryotic translocon-associated protein beta (TRAPB) or signal sequence receptor beta subunit (SSR-beta) proteins. The normal translocation of nascent polypeptides into the lumen of the endoplasmic reticulum (ER) is thought to be aided in part by a translocon-associated protein (TRAP) complex consisting of 4 protein subunits. The association of mature proteins with the ER and Golgi, or other intracellular locales, such as lysosomes, depends on the initial targeting of the nascent polypeptide to the ER membrane. A similar scenario must also exist for proteins destined for secretion.


The actual alignment was detected with superfamily member pfam05753:

Pssm-ID: 399046  Cd Length: 178  Bit Score: 165.98  E-value: 1.71e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277098206  28 DVPFIVAHKKATLSSLKSGAERVSVSIDIYNQGSSTAYDITLVDDHWPQDMFNVVSGNTSQSWERLHAGGLLSHSFELDG 107
Cdd:pfam05753  15 DAPARLLVKKKILNRYLVEGRDLTVTYTIYNVGSSAAYDVSLVDNSFPEEAFEVVSGSLSASWERLAPGSNVSHIFVVEP 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277098206 108 KVKGLFLGSPAVITFRIPTK-AALQEAYSTPILPLDVLADKPPVQKLEWAkklLVKYGSLISVISIVVLFVYLLVTPSKS 186
Cdd:pfam05753  95 KKSGYFNFTAAEVTYRPSEDgAELQVAYSSPPGEGGIFAERDYGKKFSLH---LLDWVAFAVMTLPSLGIPYLLWWVSKS 171


                  ....*..
gi 2277098206 187 GAAKSGK 193
Cdd:pfam05753 172 KYETSKK 178
 
Name Accession Description Interval E-value
TRAP_beta pfam05753
Translocon-associated protein beta (TRAPB); This family consists of several eukaryotic ...
 28-193 1.71e-52

Translocon-associated protein beta (TRAPB); This family consists of several eukaryotic translocon-associated protein beta (TRAPB) or signal sequence receptor beta subunit (SSR-beta) proteins. The normal translocation of nascent polypeptides into the lumen of the endoplasmic reticulum (ER) is thought to be aided in part by a translocon-associated protein (TRAP) complex consisting of 4 protein subunits. The association of mature proteins with the ER and Golgi, or other intracellular locales, such as lysosomes, depends on the initial targeting of the nascent polypeptide to the ER membrane. A similar scenario must also exist for proteins destined for secretion.


Pssm-ID: 399046  Cd Length: 178  Bit Score: 165.98  E-value: 1.71e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277098206  28 DVPFIVAHKKATLSSLKSGAERVSVSIDIYNQGSSTAYDITLVDDHWPQDMFNVVSGNTSQSWERLHAGGLLSHSFELDG 107
Cdd:pfam05753  15 DAPARLLVKKKILNRYLVEGRDLTVTYTIYNVGSSAAYDVSLVDNSFPEEAFEVVSGSLSASWERLAPGSNVSHIFVVEP 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277098206 108 KVKGLFLGSPAVITFRIPTK-AALQEAYSTPILPLDVLADKPPVQKLEWAkklLVKYGSLISVISIVVLFVYLLVTPSKS 186
Cdd:pfam05753  95 KKSGYFNFTAAEVTYRPSEDgAELQVAYSSPPGEGGIFAERDYGKKFSLH---LLDWVAFAVMTLPSLGIPYLLWWVSKS 171


                  ....*..
gi 2277098206 187 GAAKSGK 193
Cdd:pfam05753 172 KYETSKK 178
 
Name Accession Description Interval E-value
TRAP_beta pfam05753
Translocon-associated protein beta (TRAPB); This family consists of several eukaryotic ...
 28-193 1.71e-52

Translocon-associated protein beta (TRAPB); This family consists of several eukaryotic translocon-associated protein beta (TRAPB) or signal sequence receptor beta subunit (SSR-beta) proteins. The normal translocation of nascent polypeptides into the lumen of the endoplasmic reticulum (ER) is thought to be aided in part by a translocon-associated protein (TRAP) complex consisting of 4 protein subunits. The association of mature proteins with the ER and Golgi, or other intracellular locales, such as lysosomes, depends on the initial targeting of the nascent polypeptide to the ER membrane. A similar scenario must also exist for proteins destined for secretion.


Pssm-ID: 399046  Cd Length: 178  Bit Score: 165.98  E-value: 1.71e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277098206  28 DVPFIVAHKKATLSSLKSGAERVSVSIDIYNQGSSTAYDITLVDDHWPQDMFNVVSGNTSQSWERLHAGGLLSHSFELDG 107
Cdd:pfam05753  15 DAPARLLVKKKILNRYLVEGRDLTVTYTIYNVGSSAAYDVSLVDNSFPEEAFEVVSGSLSASWERLAPGSNVSHIFVVEP 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2277098206 108 KVKGLFLGSPAVITFRIPTK-AALQEAYSTPILPLDVLADKPPVQKLEWAkklLVKYGSLISVISIVVLFVYLLVTPSKS 186
Cdd:pfam05753  95 KKSGYFNFTAAEVTYRPSEDgAELQVAYSSPPGEGGIFAERDYGKKFSLH---LLDWVAFAVMTLPSLGIPYLLWWVSKS 171


                  ....*..
gi 2277098206 187 GAAKSGK 193
Cdd:pfam05753 172 KYETSKK 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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