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Conserved domains on  [gi|2130376459|gb|KAH7592490|]
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BAH domain profile [[Candida] glabrata]

Protein Classification

BAH_Orc1p_Yeast domain-containing protein( domain architecture ID 10140583)

BAH_Orc1p_Yeast domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
BAH_Orc1p_Yeast cd04720
BAH, or Bromo Adjacent Homology domain, as present in Orc1p, which again is part of the ...
5-188 8.53e-67

BAH, or Bromo Adjacent Homology domain, as present in Orc1p, which again is part of the Saccharomyces cerevisiae Sir1-origin recognition complex, and as present in Sir3p. The Orc1p BAH doman functions in epigenetic silencing. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


:

Pssm-ID: 240071  Cd Length: 179  Bit Score: 222.29  E-value: 8.53e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130376459    5 IKDLEGWQIIIKDQDGNVMDERDRK------VRRKRNVSTDLFIFREKDALTFGRGQNVVVHDEVSDSYAVYLIHEIRQN 78
Cdd:cd04720      1 LKDLKGWQIIITDEKGNGIDERNRRgetrrsRRRPRQAKRKIFLARDSDGLELSVGDTILVKDDVANSPSVYLIHEIRLN 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130376459   79 TLNHALEILCFTYLRWFELEPRDYYKEFKPEylsmtnqqitekFLEEIDRDEIYLTAEITPIWLKDFIDIAEVYNAKKW- 157
Cdd:cd04720     81 TLNNEVELWVMWFLRWFEINPARYYKQFDPE------------FRSESNKNELYLTAELSEIKLKDIIDKANVLSESEFn 148
                          170       180       190
                   ....*....|....*....|....*....|.
gi 2130376459  158 AQVRQSVNKERNFLVRYVCEPVAENFVPVDI 188
Cdd:cd04720    149 DLSTDDKNGERTFFCRYACEPDGEEFVWIDI 179
 
Name Accession Description Interval E-value
BAH_Orc1p_Yeast cd04720
BAH, or Bromo Adjacent Homology domain, as present in Orc1p, which again is part of the ...
5-188 8.53e-67

BAH, or Bromo Adjacent Homology domain, as present in Orc1p, which again is part of the Saccharomyces cerevisiae Sir1-origin recognition complex, and as present in Sir3p. The Orc1p BAH doman functions in epigenetic silencing. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240071  Cd Length: 179  Bit Score: 222.29  E-value: 8.53e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130376459    5 IKDLEGWQIIIKDQDGNVMDERDRK------VRRKRNVSTDLFIFREKDALTFGRGQNVVVHDEVSDSYAVYLIHEIRQN 78
Cdd:cd04720      1 LKDLKGWQIIITDEKGNGIDERNRRgetrrsRRRPRQAKRKIFLARDSDGLELSVGDTILVKDDVANSPSVYLIHEIRLN 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130376459   79 TLNHALEILCFTYLRWFELEPRDYYKEFKPEylsmtnqqitekFLEEIDRDEIYLTAEITPIWLKDFIDIAEVYNAKKW- 157
Cdd:cd04720     81 TLNNEVELWVMWFLRWFEINPARYYKQFDPE------------FRSESNKNELYLTAELSEIKLKDIIDKANVLSESEFn 148
                          170       180       190
                   ....*....|....*....|....*....|.
gi 2130376459  158 AQVRQSVNKERNFLVRYVCEPVAENFVPVDI 188
Cdd:cd04720    149 DLSTDDKNGERTFFCRYACEPDGEEFVWIDI 179
BAH pfam01426
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been ...
49-186 4.40e-11

BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been called ELM1 and BAM (Bromo adjacent motif) domain. The function of this domain is unknown but may be involved in protein-protein interaction.


Pssm-ID: 460207  Cd Length: 120  Bit Score: 61.17  E-value: 4.40e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130376459   49 LTFGRGQNVVVHDEVSD-SYAVYLIHEIRQNTLNHAleilCFTYLRWFeLEPRDYYKEFKPEYLSmtnqqitekfleeid 127
Cdd:pfam01426    1 ETYSVGDFVLVEPDDADePYYVARIEELFEDTKNGK----KMVRVQWF-YRPEETVHRAGKAFNK--------------- 60
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130376459  128 rDEIYLTAEITPIWLKDFIDIAEVYNAKKWAQVRQSVNKERN-FLVRYVCEPVAENFVPV 186
Cdd:pfam01426   61 -DELFLSDEEDDVPLSAIIGKCSVLHKSDLESLDPYKIKEPDdFFCELLYDPKTKSFKKL 119
 
Name Accession Description Interval E-value
BAH_Orc1p_Yeast cd04720
BAH, or Bromo Adjacent Homology domain, as present in Orc1p, which again is part of the ...
5-188 8.53e-67

BAH, or Bromo Adjacent Homology domain, as present in Orc1p, which again is part of the Saccharomyces cerevisiae Sir1-origin recognition complex, and as present in Sir3p. The Orc1p BAH doman functions in epigenetic silencing. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions.


Pssm-ID: 240071  Cd Length: 179  Bit Score: 222.29  E-value: 8.53e-67
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130376459    5 IKDLEGWQIIIKDQDGNVMDERDRK------VRRKRNVSTDLFIFREKDALTFGRGQNVVVHDEVSDSYAVYLIHEIRQN 78
Cdd:cd04720      1 LKDLKGWQIIITDEKGNGIDERNRRgetrrsRRRPRQAKRKIFLARDSDGLELSVGDTILVKDDVANSPSVYLIHEIRLN 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130376459   79 TLNHALEILCFTYLRWFELEPRDYYKEFKPEylsmtnqqitekFLEEIDRDEIYLTAEITPIWLKDFIDIAEVYNAKKW- 157
Cdd:cd04720     81 TLNNEVELWVMWFLRWFEINPARYYKQFDPE------------FRSESNKNELYLTAELSEIKLKDIIDKANVLSESEFn 148
                          170       180       190
                   ....*....|....*....|....*....|.
gi 2130376459  158 AQVRQSVNKERNFLVRYVCEPVAENFVPVDI 188
Cdd:cd04720    149 DLSTDDKNGERTFFCRYACEPDGEEFVWIDI 179
BAH pfam01426
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been ...
49-186 4.40e-11

BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been called ELM1 and BAM (Bromo adjacent motif) domain. The function of this domain is unknown but may be involved in protein-protein interaction.


Pssm-ID: 460207  Cd Length: 120  Bit Score: 61.17  E-value: 4.40e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130376459   49 LTFGRGQNVVVHDEVSD-SYAVYLIHEIRQNTLNHAleilCFTYLRWFeLEPRDYYKEFKPEYLSmtnqqitekfleeid 127
Cdd:pfam01426    1 ETYSVGDFVLVEPDDADePYYVARIEELFEDTKNGK----KMVRVQWF-YRPEETVHRAGKAFNK--------------- 60
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130376459  128 rDEIYLTAEITPIWLKDFIDIAEVYNAKKWAQVRQSVNKERN-FLVRYVCEPVAENFVPV 186
Cdd:pfam01426   61 -DELFLSDEEDDVPLSAIIGKCSVLHKSDLESLDPYKIKEPDdFFCELLYDPKTKSFKKL 119
BAH cd04370
BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). ...
48-187 3.08e-10

BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in mammalian DNA methyltransferases and the MTA1 subunits of histone deacetylase complexes. A BAH domain is also found in Yeast Sir3p and in the origin receptor complex protein 1 (Orc1p), where it was found to interact with the N-terminal lobe of the silence information regulator 1 protein (Sir1p), confirming the initial hypothesis that BAH plays a role in protein-protein interactions.


Pssm-ID: 239835 [Multi-domain]  Cd Length: 123  Bit Score: 58.94  E-value: 3.08e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130376459   48 ALTFGRGQNVVVHDE---VSDSYAVYLIHEIRQNTLNHaLEILCFTYLRWFELEPRDYYkefkpeylsmtnqqitekfle 124
Cdd:cd04370      1 GITYEVGDSVYVEPDdsiKSDPPYIARIEELWEDTNGS-KQVKVRWFYRPEETPKGLSP--------------------- 58
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2130376459  125 EIDRDEIYLTAEITPIWLKDFIDIAEVYNAKKWAQVRQSVNKERN--FLVRYVCEPVAENFVPVD 187
Cdd:cd04370     59 FALRRELFLSDHLDEIPVESIIGKCKVLFVSEFEGLKQRPNKIDTddFFCRLAYDPTTKEFKALE 123
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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