|
Name |
Accession |
Description |
Interval |
E-value |
| Thg1 |
pfam04446 |
tRNAHis guanylyltransferase; The Thg1 protein from Saccharomyces cerevisiae is responsible for ... |
6-136 |
1.20e-70 |
|
tRNAHis guanylyltransferase; The Thg1 protein from Saccharomyces cerevisiae is responsible for adding a GMP residue to the 5' end of tRNA His. The catalytic domain Thg1 contains a RRM (ferredoxin) fold palm domain, just like the viral RNA-dependent RNA polymerases, reverse transcriptases, family A and B DNA polymerases, adenylyl cyclases, diguanylate cyclases (GGDEF domain) and the predicted polymerase of the CRISPR system. Thg1 possesses an active site with three acidic residues that chelate Mg++ cations. Thg1 catalyzes polymerization similar to the 5'-3' polymerases.
:
Pssm-ID: 461314 Cd Length: 130 Bit Score: 226.60 E-value: 1.20e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 6 YEYVRLFEQPDNLLANTWIVVRIDGRGFSKLTTKYKFVKPNDRHALDLMNAAAEAVMKELPDLVLAYGNSDEYSFVFHKD 85
Cdd:pfam04446 1 YEYVKSFEQDDKLLPNTWIVVRIDGRGFHKFSKKHGFEKPNDERALDLMNEAAKDVMEEFPDIVLAYGQSDEYSFVFRKS 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 2128589122 86 CILFERRASKLTTTITSTFTSYYVFLWSQYFPEKPLTPPlPSFDGRAVCYP 136
Cdd:pfam04446 81 TTLFNRRVSKLVSLVASLFSSSYVFLWSKFFPDKPLLYP-PSFDGRAVLYP 130
|
|
| Thg1C |
pfam14413 |
Thg1 C terminal domain; Thg1 polymerases contain an additional region of conservation ... |
140-236 |
1.15e-60 |
|
Thg1 C terminal domain; Thg1 polymerases contain an additional region of conservation C-terminal to the core palm domain that comprise of 5 helices and two strands. This region has several well-conserved charged residues including a basic residue found towards the end of the first helix of this unit might contribute to the Thg1-specific active site. This C-terminal module of Thg1 is predicted to form a helical bundle that functions equivalently to the fingers of the other nucleic acid polymerases, probably in interacting with the template HtRNA.
:
Pssm-ID: 464167 Cd Length: 116 Bit Score: 199.29 E-value: 1.15e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 140 NLRDYMSWRQVDCHINNLYNTTFWTLVQQGGMGPREAEQRLSGTVSADKNEILFKEFGINYNNEPECFKKGTVLYRdffp 219
Cdd:pfam14413 2 NLRDYLSWRQVDCHINNLYNTTFWALVQKGGLTPTEAEERLKGTVSADKNEILFSEFGINYNNEPEIFRKGSVLVR---- 77
|
90
....*....|....*..
gi 2128589122 220 vsaPEQTVSATQPPETS 236
Cdd:pfam14413 78 ---EEVEETVTKPTELS 91
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
219-647 |
2.02e-07 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 54.94 E-value: 2.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 219 PVSAPEQTVSATQPPETSPTIASPRPARSSVAN--PLRPLESAIPflPDQTLLQTPADPGPTflsttstPSPPNSPEAML 296
Cdd:PHA03247 2645 TVPPPERPRDDPAPGRVSRPRRARRLGRAAQASspPQRPRRRAAR--PTVGSLTSLADPPPP-------PPTPEPAPHAL 2715
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 297 TSALPNPLrsNPVSPRSSSYPPVSMPISPPstvtSPMGSLYPTA-GPKQPLPNLMPLPLSPPILKPSTKPPLSLNAPNPT 375
Cdd:PHA03247 2716 VSATPLPP--GPAAARQASPALPAAPAPPA----VPAGPATPGGpARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVA 2789
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 376 TRSNFSPISPDYDFPAAYPIAGYSHNTSSNTQRPTSHSASASLTLANYSPPqqhrlKQRSPSQPHLPSYFSV-------- 447
Cdd:PHA03247 2790 SLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP-----PPPGPPPPSLPLGGSVapggdvrr 2864
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 448 ---PQQPPVIPLRISSIPTNNKPRKLSLNKHQSMST--LKPRRHSEEKEIVSADTHRRSSPPRRVSPPLRTnKALPSPPM 522
Cdd:PHA03247 2865 rppSRSPAAKPAAPARPPVRRLARPAVSRSTESFALppDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP-PPRPQPPL 2943
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 523 NAEEELQTRQKVMSSGSQDW--SMFSTTRDSPPRRVSENykrggqvwtGPGRDeeighpgiAELPNTPARRAQSHTRLHS 600
Cdd:PHA03247 2944 APTTDPAGAGEPSGAVPQPWlgALVPGRVAVPRFRVPQP---------APSRE--------APASSTPPLTGHSLSRVSS 3006
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 601 -----------APVSASLYQPFQSPDVQALSSAVAA--QSTLDADIQPTAPLKDSPRSKP 647
Cdd:PHA03247 3007 wasslalheetDPPPVSLKQTLWPPDDTEDSDADSLfdSDSERSDLEALDPLPPEPHDPF 3066
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Thg1 |
pfam04446 |
tRNAHis guanylyltransferase; The Thg1 protein from Saccharomyces cerevisiae is responsible for ... |
6-136 |
1.20e-70 |
|
tRNAHis guanylyltransferase; The Thg1 protein from Saccharomyces cerevisiae is responsible for adding a GMP residue to the 5' end of tRNA His. The catalytic domain Thg1 contains a RRM (ferredoxin) fold palm domain, just like the viral RNA-dependent RNA polymerases, reverse transcriptases, family A and B DNA polymerases, adenylyl cyclases, diguanylate cyclases (GGDEF domain) and the predicted polymerase of the CRISPR system. Thg1 possesses an active site with three acidic residues that chelate Mg++ cations. Thg1 catalyzes polymerization similar to the 5'-3' polymerases.
Pssm-ID: 461314 Cd Length: 130 Bit Score: 226.60 E-value: 1.20e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 6 YEYVRLFEQPDNLLANTWIVVRIDGRGFSKLTTKYKFVKPNDRHALDLMNAAAEAVMKELPDLVLAYGNSDEYSFVFHKD 85
Cdd:pfam04446 1 YEYVKSFEQDDKLLPNTWIVVRIDGRGFHKFSKKHGFEKPNDERALDLMNEAAKDVMEEFPDIVLAYGQSDEYSFVFRKS 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 2128589122 86 CILFERRASKLTTTITSTFTSYYVFLWSQYFPEKPLTPPlPSFDGRAVCYP 136
Cdd:pfam04446 81 TTLFNRRVSKLVSLVASLFSSSYVFLWSKFFPDKPLLYP-PSFDGRAVLYP 130
|
|
| Thg1C |
pfam14413 |
Thg1 C terminal domain; Thg1 polymerases contain an additional region of conservation ... |
140-236 |
1.15e-60 |
|
Thg1 C terminal domain; Thg1 polymerases contain an additional region of conservation C-terminal to the core palm domain that comprise of 5 helices and two strands. This region has several well-conserved charged residues including a basic residue found towards the end of the first helix of this unit might contribute to the Thg1-specific active site. This C-terminal module of Thg1 is predicted to form a helical bundle that functions equivalently to the fingers of the other nucleic acid polymerases, probably in interacting with the template HtRNA.
Pssm-ID: 464167 Cd Length: 116 Bit Score: 199.29 E-value: 1.15e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 140 NLRDYMSWRQVDCHINNLYNTTFWTLVQQGGMGPREAEQRLSGTVSADKNEILFKEFGINYNNEPECFKKGTVLYRdffp 219
Cdd:pfam14413 2 NLRDYLSWRQVDCHINNLYNTTFWALVQKGGLTPTEAEERLKGTVSADKNEILFSEFGINYNNEPEIFRKGSVLVR---- 77
|
90
....*....|....*..
gi 2128589122 220 vsaPEQTVSATQPPETS 236
Cdd:pfam14413 78 ---EEVEETVTKPTELS 91
|
|
| Thg1 |
COG4021 |
tRNA(His) 5'-end guanylyltransferase [Translation, ribosomal structure and biogenesis]; tRNA ... |
10-230 |
5.05e-35 |
|
tRNA(His) 5'-end guanylyltransferase [Translation, ribosomal structure and biogenesis]; tRNA(His) 5'-end guanylyltransferase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443199 [Multi-domain] Cd Length: 235 Bit Score: 133.06 E-value: 5.05e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 10 RLFEQPDNL--LANTWIVVRIDGRGFSKLTTKYKFVKPNDRHALDLMNAAAEAVMKELP-DLVLAYGNSDEYSFVFhkDC 86
Cdd:COG4021 2 RVREIFHDLrvLPGLPVVVRLDGRGFTRLTKELGFEKPFDERFRDAMVETAEHLMKESGfSPVYAYTFSDEISLLF--DE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 87 ILFERRASKLTTTITStftsyyvFLWSQ--YFPEKPLtpplpSFDGRAVCYPSDfNLRDYMSWRQVDCHINNLYNTTFWT 164
Cdd:COG4021 80 LPFDRRVEKLDSVLAG-------EASAAftLALGEPV-----AFDCRIIPLPNE-LVVDYFRWRQEEAWRNALNAYCYWT 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2128589122 165 LVQQgGMGPREAEQRLSGTVSADKNEILFkEFGINYNNEPECFKKGTVLYRD------FFPVSapEQTVSAT 230
Cdd:COG4021 147 LRKE-GMSPREAAARLKGMKVAEKHELLF-QRGINFNDLPAWQRRGIGVYWEeyekegYNPVT--GEKVLTT 214
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
219-647 |
2.02e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 54.94 E-value: 2.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 219 PVSAPEQTVSATQPPETSPTIASPRPARSSVAN--PLRPLESAIPflPDQTLLQTPADPGPTflsttstPSPPNSPEAML 296
Cdd:PHA03247 2645 TVPPPERPRDDPAPGRVSRPRRARRLGRAAQASspPQRPRRRAAR--PTVGSLTSLADPPPP-------PPTPEPAPHAL 2715
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 297 TSALPNPLrsNPVSPRSSSYPPVSMPISPPstvtSPMGSLYPTA-GPKQPLPNLMPLPLSPPILKPSTKPPLSLNAPNPT 375
Cdd:PHA03247 2716 VSATPLPP--GPAAARQASPALPAAPAPPA----VPAGPATPGGpARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVA 2789
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 376 TRSNFSPISPDYDFPAAYPIAGYSHNTSSNTQRPTSHSASASLTLANYSPPqqhrlKQRSPSQPHLPSYFSV-------- 447
Cdd:PHA03247 2790 SLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP-----PPPGPPPPSLPLGGSVapggdvrr 2864
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 448 ---PQQPPVIPLRISSIPTNNKPRKLSLNKHQSMST--LKPRRHSEEKEIVSADTHRRSSPPRRVSPPLRTnKALPSPPM 522
Cdd:PHA03247 2865 rppSRSPAAKPAAPARPPVRRLARPAVSRSTESFALppDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP-PPRPQPPL 2943
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 523 NAEEELQTRQKVMSSGSQDW--SMFSTTRDSPPRRVSENykrggqvwtGPGRDeeighpgiAELPNTPARRAQSHTRLHS 600
Cdd:PHA03247 2944 APTTDPAGAGEPSGAVPQPWlgALVPGRVAVPRFRVPQP---------APSRE--------APASSTPPLTGHSLSRVSS 3006
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 601 -----------APVSASLYQPFQSPDVQALSSAVAA--QSTLDADIQPTAPLKDSPRSKP 647
Cdd:PHA03247 3007 wasslalheetDPPPVSLKQTLWPPDDTEDSDADSLfdSDSERSDLEALDPLPPEPHDPF 3066
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
281-521 |
1.25e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 42.45 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 281 STTSTPSPPNSPEAMLTSALPNPLRSNPVSPRSSSYPPVsmPISPPSTVTSPMGSLYPTAGPKQPLPNLMPLPLSPPILK 360
Cdd:pfam03154 144 TSPSIPSPQDNESDSDSSAQQQILQTQPPVLQAQSGAAS--PPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQT 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 361 PSTKPPLSLNAPNPTTRSNFSPiSPDYDFPAAYPIAGYSHNTSSNTQRPTSHS---------ASASLTLANYSPPQQHRL 431
Cdd:pfam03154 222 QSTAAPHTLIQQTPTLHPQRLP-SPHPPLQPMTQPPPPSQVSPQPLPQPSLHGqmppmphslQTGPSHMQHPVPPQPFPL 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 432 -KQRSPSQPHLPSYFSVP---QQPPVIPLRISSIPTNNKPRKLSLNKH-QSMSTLKPRRHSEEKEIVSADTHRRssPPRR 506
Cdd:pfam03154 301 tPQSSQSQVPPGPSPAAPgqsQQRIHTPPSQSQLQSQQPPREQPLPPApLSMPHIKPPPTTPIPQLPNPQSHKH--PPHL 378
|
250
....*....|....*.
gi 2128589122 507 VSP-PLRTNKALPSPP 521
Cdd:pfam03154 379 SGPsPFQMNSNLPPPP 394
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Thg1 |
pfam04446 |
tRNAHis guanylyltransferase; The Thg1 protein from Saccharomyces cerevisiae is responsible for ... |
6-136 |
1.20e-70 |
|
tRNAHis guanylyltransferase; The Thg1 protein from Saccharomyces cerevisiae is responsible for adding a GMP residue to the 5' end of tRNA His. The catalytic domain Thg1 contains a RRM (ferredoxin) fold palm domain, just like the viral RNA-dependent RNA polymerases, reverse transcriptases, family A and B DNA polymerases, adenylyl cyclases, diguanylate cyclases (GGDEF domain) and the predicted polymerase of the CRISPR system. Thg1 possesses an active site with three acidic residues that chelate Mg++ cations. Thg1 catalyzes polymerization similar to the 5'-3' polymerases.
Pssm-ID: 461314 Cd Length: 130 Bit Score: 226.60 E-value: 1.20e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 6 YEYVRLFEQPDNLLANTWIVVRIDGRGFSKLTTKYKFVKPNDRHALDLMNAAAEAVMKELPDLVLAYGNSDEYSFVFHKD 85
Cdd:pfam04446 1 YEYVKSFEQDDKLLPNTWIVVRIDGRGFHKFSKKHGFEKPNDERALDLMNEAAKDVMEEFPDIVLAYGQSDEYSFVFRKS 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 2128589122 86 CILFERRASKLTTTITSTFTSYYVFLWSQYFPEKPLTPPlPSFDGRAVCYP 136
Cdd:pfam04446 81 TTLFNRRVSKLVSLVASLFSSSYVFLWSKFFPDKPLLYP-PSFDGRAVLYP 130
|
|
| Thg1C |
pfam14413 |
Thg1 C terminal domain; Thg1 polymerases contain an additional region of conservation ... |
140-236 |
1.15e-60 |
|
Thg1 C terminal domain; Thg1 polymerases contain an additional region of conservation C-terminal to the core palm domain that comprise of 5 helices and two strands. This region has several well-conserved charged residues including a basic residue found towards the end of the first helix of this unit might contribute to the Thg1-specific active site. This C-terminal module of Thg1 is predicted to form a helical bundle that functions equivalently to the fingers of the other nucleic acid polymerases, probably in interacting with the template HtRNA.
Pssm-ID: 464167 Cd Length: 116 Bit Score: 199.29 E-value: 1.15e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 140 NLRDYMSWRQVDCHINNLYNTTFWTLVQQGGMGPREAEQRLSGTVSADKNEILFKEFGINYNNEPECFKKGTVLYRdffp 219
Cdd:pfam14413 2 NLRDYLSWRQVDCHINNLYNTTFWALVQKGGLTPTEAEERLKGTVSADKNEILFSEFGINYNNEPEIFRKGSVLVR---- 77
|
90
....*....|....*..
gi 2128589122 220 vsaPEQTVSATQPPETS 236
Cdd:pfam14413 78 ---EEVEETVTKPTELS 91
|
|
| Thg1 |
COG4021 |
tRNA(His) 5'-end guanylyltransferase [Translation, ribosomal structure and biogenesis]; tRNA ... |
10-230 |
5.05e-35 |
|
tRNA(His) 5'-end guanylyltransferase [Translation, ribosomal structure and biogenesis]; tRNA(His) 5'-end guanylyltransferase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443199 [Multi-domain] Cd Length: 235 Bit Score: 133.06 E-value: 5.05e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 10 RLFEQPDNL--LANTWIVVRIDGRGFSKLTTKYKFVKPNDRHALDLMNAAAEAVMKELP-DLVLAYGNSDEYSFVFhkDC 86
Cdd:COG4021 2 RVREIFHDLrvLPGLPVVVRLDGRGFTRLTKELGFEKPFDERFRDAMVETAEHLMKESGfSPVYAYTFSDEISLLF--DE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 87 ILFERRASKLTTTITStftsyyvFLWSQ--YFPEKPLtpplpSFDGRAVCYPSDfNLRDYMSWRQVDCHINNLYNTTFWT 164
Cdd:COG4021 80 LPFDRRVEKLDSVLAG-------EASAAftLALGEPV-----AFDCRIIPLPNE-LVVDYFRWRQEEAWRNALNAYCYWT 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2128589122 165 LVQQgGMGPREAEQRLSGTVSADKNEILFkEFGINYNNEPECFKKGTVLYRD------FFPVSapEQTVSAT 230
Cdd:COG4021 147 LRKE-GMSPREAAARLKGMKVAEKHELLF-QRGINFNDLPAWQRRGIGVYWEeyekegYNPVT--GEKVLTT 214
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
219-647 |
2.02e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 54.94 E-value: 2.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 219 PVSAPEQTVSATQPPETSPTIASPRPARSSVAN--PLRPLESAIPflPDQTLLQTPADPGPTflsttstPSPPNSPEAML 296
Cdd:PHA03247 2645 TVPPPERPRDDPAPGRVSRPRRARRLGRAAQASspPQRPRRRAAR--PTVGSLTSLADPPPP-------PPTPEPAPHAL 2715
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 297 TSALPNPLrsNPVSPRSSSYPPVSMPISPPstvtSPMGSLYPTA-GPKQPLPNLMPLPLSPPILKPSTKPPLSLNAPNPT 375
Cdd:PHA03247 2716 VSATPLPP--GPAAARQASPALPAAPAPPA----VPAGPATPGGpARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVA 2789
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 376 TRSNFSPISPDYDFPAAYPIAGYSHNTSSNTQRPTSHSASASLTLANYSPPqqhrlKQRSPSQPHLPSYFSV-------- 447
Cdd:PHA03247 2790 SLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP-----PPPGPPPPSLPLGGSVapggdvrr 2864
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 448 ---PQQPPVIPLRISSIPTNNKPRKLSLNKHQSMST--LKPRRHSEEKEIVSADTHRRSSPPRRVSPPLRTnKALPSPPM 522
Cdd:PHA03247 2865 rppSRSPAAKPAAPARPPVRRLARPAVSRSTESFALppDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP-PPRPQPPL 2943
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 523 NAEEELQTRQKVMSSGSQDW--SMFSTTRDSPPRRVSENykrggqvwtGPGRDeeighpgiAELPNTPARRAQSHTRLHS 600
Cdd:PHA03247 2944 APTTDPAGAGEPSGAVPQPWlgALVPGRVAVPRFRVPQP---------APSRE--------APASSTPPLTGHSLSRVSS 3006
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 601 -----------APVSASLYQPFQSPDVQALSSAVAA--QSTLDADIQPTAPLKDSPRSKP 647
Cdd:PHA03247 3007 wasslalheetDPPPVSLKQTLWPPDDTEDSDADSLfdSDSERSDLEALDPLPPEPHDPF 3066
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
217-697 |
8.34e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 53.02 E-value: 8.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 217 FFPVSAPEQTVSATQPPETSPTIASPRPA---RSSVANPLRP--------LE----------------SAIPFLPDQTLL 269
Cdd:PHA03247 2490 FAAGAAPDPGGGGPPDPDAPPAPSRLAPAilpDEPVGEPVHPrmltwirgLEelasddagdpppplppAAPPAAPDRSVP 2569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 270 QTPADPGPTFLSTTSTPSPPNSPEAMLTSALP-NPLRSNPVSPRSSSYPPVSMPISPPSTVTSPMGSLYPTAGPkqpLPN 348
Cdd:PHA03247 2570 PPRPAPRPSEPAVTSRARRPDAPPQSARPRAPvDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPP---PTV 2646
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 349 LMPLPLSPPILKPSTKPPLSLNAPNPTTRSNFSPISPDYdfPAAYP-IAGYSHNTSSNTQRPTSHSASASLTLANYSPPQ 427
Cdd:PHA03247 2647 PPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRR--RAARPtVGSLTSLADPPPPPPTPEPAPHALVSATPLPPG 2724
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 428 QHRLKQRSPSQPHLPSYFSVPQQP--PVIPLRISSIPTNNKPRklslnkhqsmSTLKPRrhseekeiVSADTHRRSSPPR 505
Cdd:PHA03247 2725 PAAARQASPALPAAPAPPAVPAGPatPGGPARPARPPTTAGPP----------APAPPA--------APAAGPPRRLTRP 2786
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 506 RVSPPLRTNKALPSPPMNAE---------EELQTRQKVMSSGSQDWSMFSTTRDSPPRRVSENYKRGGqvWTGPGRDEEI 576
Cdd:PHA03247 2787 AVASLSESRESLPSPWDPADppaavlapaAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGG--SVAPGGDVRR 2864
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 577 GHPGIAElPNTPARRAQSHTRLHSAPVSASLYQPFQSPDVQ-------ALSSAVAAQSTLDADIQPTAPLKDSPRSKPKP 649
Cdd:PHA03247 2865 RPPSRSP-AAKPAAPARPPVRRLARPAVSRSTESFALPPDQperppqpQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPL 2943
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 2128589122 650 GITAQNQAAIAHDSKKDKGKAKLTEKGGWAAGTQ--PQPSEGRPVQQSRT 697
Cdd:PHA03247 2944 APTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFrvPQPAPSREAPASST 2993
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
210-557 |
1.34e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.78 E-value: 1.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 210 GTVLYRDFFPvsAPEQTVSATQPPETSPTIASPR--PARSSVANPLRPLESAIPFLPDQTLLQTPAdPGPTFLSTTSTPS 287
Cdd:PHA03247 2724 GPAAARQASP--ALPAAPAPPAVPAGPATPGGPArpARPPTTAGPPAPAPPAAPAAGPPRRLTRPA-VASLSESRESLPS 2800
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 288 PPNSPEAMLTSALPNPLRSNPVSPRSSSYPPVSMPISPPSTVTSPMGSLYPTAGpkqplpnlmplpLSPPILKPSTKPPL 367
Cdd:PHA03247 2801 PWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGG------------SVAPGGDVRRRPPS 2868
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 368 SLNAPNPTTRsnfspispdydfpaaypiagySHNTSSNTQRPTSHSASASLTLanySPPQQHRLKQRSPSQPHLPsyfsv 447
Cdd:PHA03247 2869 RSPAAKPAAP---------------------ARPPVRRLARPAVSRSTESFAL---PPDQPERPPQPQAPPPPQP----- 2919
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 448 PQQPPVIPLRISSIPTNNKPRKLSLNKHQSMSTLKPRRHSEEKEIVSADTHRRSSPPRRVSPPlRTNKALPSPPMNaeee 527
Cdd:PHA03247 2920 QPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQP-APSREAPASSTP---- 2994
|
330 340 350
....*....|....*....|....*....|.
gi 2128589122 528 lqTRQKVMSSGSQDW-SMFSTTRDSPPRRVS 557
Cdd:PHA03247 2995 --PLTGHSLSRVSSWaSSLALHEETDPPPVS 3023
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
222-521 |
2.24e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 48.24 E-value: 2.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 222 APEQTVSATQPPETSPTIASPRPARSSVANPLRPLESAIPFLPDQTLLQTPADPGPTFLSTTSTPSPPNSPEAMLTSALP 301
Cdd:PHA03307 60 AACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLR 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 302 NPLRSNPVSPRSSSYPPVSmPISPPSTVTSPMGSLYPTAGPKQPLPNLMPLPLSPPILKPSTKPPLSLNAPNPTTRSNFS 381
Cdd:PHA03307 140 PVGSPGPPPAASPPAAGAS-PAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASAS 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 382 PISPDydfPAAYPIAGYSHNTSSNTQRPTSHSASASLTLANYSPPQQHRLKQR--SPSQPHLPSYFSVPQQPPVIPLRIS 459
Cdd:PHA03307 219 SPAPA---PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRiwEASGWNGPSSRPGPASSSSSPRERS 295
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2128589122 460 SIPTNNKPRKLSLNKHQSMSTLKPRRHSEEKEIVSADTHRRSSPPRRVSPPLRTNKALPSPP 521
Cdd:PHA03307 296 PSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPP 357
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
281-521 |
1.25e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 42.45 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 281 STTSTPSPPNSPEAMLTSALPNPLRSNPVSPRSSSYPPVsmPISPPSTVTSPMGSLYPTAGPKQPLPNLMPLPLSPPILK 360
Cdd:pfam03154 144 TSPSIPSPQDNESDSDSSAQQQILQTQPPVLQAQSGAAS--PPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQT 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 361 PSTKPPLSLNAPNPTTRSNFSPiSPDYDFPAAYPIAGYSHNTSSNTQRPTSHS---------ASASLTLANYSPPQQHRL 431
Cdd:pfam03154 222 QSTAAPHTLIQQTPTLHPQRLP-SPHPPLQPMTQPPPPSQVSPQPLPQPSLHGqmppmphslQTGPSHMQHPVPPQPFPL 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 432 -KQRSPSQPHLPSYFSVP---QQPPVIPLRISSIPTNNKPRKLSLNKH-QSMSTLKPRRHSEEKEIVSADTHRRssPPRR 506
Cdd:pfam03154 301 tPQSSQSQVPPGPSPAAPgqsQQRIHTPPSQSQLQSQQPPREQPLPPApLSMPHIKPPPTTPIPQLPNPQSHKH--PPHL 378
|
250
....*....|....*.
gi 2128589122 507 VSP-PLRTNKALPSPP 521
Cdd:pfam03154 379 SGPsPFQMNSNLPPPP 394
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
235-521 |
4.05e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 40.52 E-value: 4.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 235 TSPTIASPR--PARSSVANPLRPLESAIPFLPDQTLLQTPADPGPTFLSTTSTPSPPNSpeamltsalpnplrSNPVSPR 312
Cdd:pfam03154 144 TSPSIPSPQdnESDSDSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPS--------------APSVPPQ 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 313 SSsyPPVSMPISPPSTVTSPMG------SLYPTAGPK-QPLPNLMPLPLSPPILKPSTKPPLSLNAPNPTTRSNFSPISP 385
Cdd:pfam03154 210 GS--PATSQPPNQTQSTAAPHTliqqtpTLHPQRLPSpHPPLQPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQTGPS 287
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 386 DYDFPAA-YPIAGYSHNTSSNTQRPTSHSASASLTLANYSPPQQHRLKQRSP--SQPHLPSYFSVP--QQPPVIPLRISS 460
Cdd:pfam03154 288 HMQHPVPpQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPprEQPLPPAPLSMPhiKPPPTTPIPQLP 367
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2128589122 461 IPTNNK-PRKLSLNKHQSMSTLKPRRHSeEKEIVSADTHRrssPPRRVSPPLR---TNKALPSPP 521
Cdd:pfam03154 368 NPQSHKhPPHLSGPSPFQMNSNLPPPPA-LKPLSSLSTHH---PPSAHPPPLQlmpQSQQLPPPP 428
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
271-663 |
5.15e-03 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 40.42 E-value: 5.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 271 TPADPGPTFLSTTSTPSPPNSPEAMLTSALPNPLRSNPVSPRSSSYPPVSMP-------------------------ISP 325
Cdd:PHA03377 449 TPERPGPSDQPSVPVEPAHLTPVEHTTVILHQPPQSPPTVAIKPAPPPSRRRrgacvvydddiievidvetteeeesVTQ 528
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 326 PSTVTSPMGSLYPTAGPKQPLPNLMPLPLSPPILKPSTKPPLSLNAPNPTTRSNFSPISPDYDFPAAYP--IAGYSHNTS 403
Cdd:PHA03377 529 PAKPHRKVQDGFQRSGRRQKRATPPKVSPSDRGPPKASPPVMAPPSTGPRVMATPSTGPRDMAPPSTGPrqQAKCKDGPP 608
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 404 SNTQRPTSHSASASLTLAnysPPQQHRL----------------------------KQRSPSQPHLPSYFSVPQQPPVIP 455
Cdd:PHA03377 609 ASGPHEKQPPSSAPRDMA---PSVVRMFlrerlleqstgpkpksfwemragrdgsgIQQEPSSRRQPATQSTPPRPSWLP 685
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 456 --LRISSIPTNNkPRKLSLNKHQSMSTLKPRRHSEEKEIVSADThrrssPPRRVSPPLRTNKALPSPPMNAEEELQTRQK 533
Cdd:PHA03377 686 svFVLPSVDAGR-AQPSEESHLSSMSPTQPISHEEQPRYEDPDD-----PLDLSLHPDQAPPPSHQAPYSGHEEPQAQQA 759
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 534 -----------------VMSSGSQDWSMFSTTRDSPPRRVSENYKRGGQVWTGPGRDEEIGHPGIAELPNTP-------- 588
Cdd:PHA03377 760 pypgyweprppqapylgYQEPQAQGVQVSSYPGYAGPWGLRAQHPRYRHSWAYWSQYPGHGHPQGPWAPRPPhlppqwdg 839
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 589 -ARRAQSHTR----LHSAPVSASLYQPfQSPDVQALSSAVAAQSTLDADIQPTAPLKDSPRSKPKPGITAQNQAAIAHDS 663
Cdd:PHA03377 840 sAGHGQDQVSqfphLQSETGPPRLQLS-QVPQLPYSQTLVSSSAPSWSSPQPRAPIRPIPTRFPPPPMPLQDSMAVGCDS 918
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
219-332 |
8.79e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 39.31 E-value: 8.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 219 PVSAPEQTVSATQPPETSPTIASPRPARSSVANPLRPLESAIPFLPDQTLLQTPADPGPTFLSTTSTPSPPNSPEAMLTS 298
Cdd:PRK14951 381 PARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPETV 460
|
90 100 110
....*....|....*....|....*....|....
gi 2128589122 299 ALPNPLRSNPvSPRSSSYPPVSMPISPPSTVTSP 332
Cdd:PRK14951 461 AIPVRVAPEP-AVASAAPAPAAAPAAARLTPTEE 493
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
219-454 |
9.41e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 39.37 E-value: 9.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 219 PVSAPEQTVSATQPPETSPTIASPRPARSsvanplRPLESAIPFLPDQTLLQTPADPGPTFLSTTSTP----SPPNSPEA 294
Cdd:pfam03154 187 PPPGTTQAATAGPTPSAPSVPPQGSPATS------QPPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPlqpmTQPPPPSQ 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 295 MLTSALPNPLRSNPVSPRSSSY-----------PPVSMPISPPSTVTS-PMGSLYPTAGPKQPLPNLMPLPLSPPILKPS 362
Cdd:pfam03154 261 VSPQPLPQPSLHGQMPPMPHSLqtgpshmqhpvPPQPFPLTPQSSQSQvPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPP 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 363 TKPPLSlNAPNPTTRSNFSPISPDYDFPAAypiagYSHNTSSNTQRPTSHSASASL----------TLANYSPPQQH--R 430
Cdd:pfam03154 341 REQPLP-PAPLSMPHIKPPPTTPIPQLPNP-----QSHKHPPHLSGPSPFQMNSNLppppalkplsSLSTHHPPSAHppP 414
|
250 260
....*....|....*....|....
gi 2128589122 431 LKQRSPSQPHLPSyfsvPQQPPVI 454
Cdd:pfam03154 415 LQLMPQSQQLPPP----PAQPPVL 434
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
219-343 |
9.65e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 39.47 E-value: 9.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2128589122 219 PVSAPEQTVSATQPPETSPTIASPRPARSSVANPLRPLESAIPflPDQTLLQTPADPGPTFLSTTSTPSPPNSPEAmlts 298
Cdd:PRK12323 374 PATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAA--RAVAAAPARRSPAPEALAAARQASARGPGGA---- 447
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2128589122 299 alPNPLRSNPVSPRSSSYPPVSMPISPPSTVTSPMGSLYPTAGPK 343
Cdd:PRK12323 448 --PAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPA 490
|
|
| |
