|
Name |
Accession |
Description |
Interval |
E-value |
| PRK12830 |
PRK12830 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed |
3-419 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed
Pssm-ID: 183779 Cd Length: 417 Bit Score: 744.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 3 QEVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKASLNGTELEVDTTEIQN 82
Cdd:PRK12830 1 MEKIVINGGKPLSGEVTISGAKNSAVALIPAAILADGPVTLDGVPDISDVHSLVDILEELGGKVKRDGDTLEIDPTGIQS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 83 AALPNNKVESLRASYYMMGTMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESSTtSMKIEAKELKGAHIFLD 162
Cdd:PRK12830 81 MPLPNGKVKSLRASYYFMGALLGRFKKAVVGLPGGCDLGPRPIDQHIKGFEALGAEVTNEGG-AIYLKADELKGAHIYLD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 163 MVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGTYM 242
Cdd:PRK12830 160 VVSVGATINIMLAAVKAKGRTVIENAAKEPEIIDVATLLNNMGANIKGAGTDVIRIEGVDELHGCRHTVIPDRIEAGTYM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 243 CIAAACGENVILNNIVPKHVETLTAKFSELGVNVDVRDERIRINNNAPYQFVDIKTLVYPGFATDLQQPITPLLFMANGP 322
Cdd:PRK12830 240 ILAAACGGGVTINNVIPEHLESFIAKLEEMGVRVEVNEDSIFVEKQGNLKAVDIKTLPYPGFATDLQQPLTPLLLKANGR 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 323 SFVTDTIYPERFKHVEELKRMGANIEVDEGTATIK-PSTLHGADVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRGYT 401
Cdd:PRK12830 320 SVVTDTIYEKRFKHVDELKRMGANIKVEGRSAIITgPSKLTGAKVKATDLRAGAALVIAGLMAEGVTEITNIEHIDRGYS 399
|
410
....*....|....*...
gi 616915692 402 DIVEHLKALGADIWTETV 419
Cdd:PRK12830 400 NIIEKLKALGADIWREED 417
|
|
| MurA |
COG0766 |
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; ... |
4-415 |
0e+00 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine enolpyruvyl transferase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440529 Cd Length: 416 Bit Score: 624.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 4 EVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKAS-LNGTELEVDTTEIQN 82
Cdd:COG0766 2 DKLIIEGGKPLSGEVRISGAKNAALPILAAALLTDGPVTLRNVPDLSDVRTMLELLESLGVKVErDDGGTLTIDASNINS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 83 AALPNNKVESLRASYYMMGTMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESSTtSMKIEAKELKGAHIFLD 162
Cdd:COG0766 82 TEAPYELVRKMRASILVLGPLLARFGEARVSLPGGCAIGARPIDLHLKGLEALGAEIEIEHG-YIEARAGRLKGARIYLD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 163 MVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGTYM 242
Cdd:COG0766 161 FPSVGATENIMMAAVLAEGTTVIENAAREPEIVDLANFLNAMGAKIEGAGTDTITIEGVEKLHGAEHTVIPDRIEAGTFL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 243 CIAAACGENVILNNIVPKHVETLTAKFSELGVNVDVRDERIRINNNAPYQFVDIKTLVYPGFATDLQQPITPLLFMANGP 322
Cdd:COG0766 241 VAAAITGGDVTVKNVIPEHLEAVLAKLREAGVEIEEGDDGIRVRGPGRLKAVDIKTAPYPGFPTDLQAQFMALLTQAEGT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 323 SFVTDTIYPERFKHVEELKRMGANIEVDEGTATIK-PSTLHGADVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRGYT 401
Cdd:COG0766 321 SVITETVFENRFMHVDELNRMGADIKLDGHTAIVRgVTKLSGAPVMATDLRAGAALVLAGLAAEGETVIDNIYHIDRGYE 400
|
410
....*....|....
gi 616915692 402 DIVEHLKALGADIW 415
Cdd:COG0766 401 NLEEKLRALGADIE 414
|
|
| UdpNAET |
cd01555 |
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the ... |
14-410 |
0e+00 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine. This enzyme is of interest as a potential target for anti-bacterial agents. The only other known enolpyruvyl transferase is the related 5-enolpyruvylshikimate-3-phosphate synthase.
Pssm-ID: 238796 Cd Length: 400 Bit Score: 591.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 14 LNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKASLNGT-ELEVDTTEIQNAALPNNKVES 92
Cdd:cd01555 1 LSGEVRISGAKNAALPILAAALLTDEPVTLRNVPDLLDVETMIELLRSLGAKVEFEGEnTLVIDASNINSTEAPYELVRK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 93 LRASYYMMGTMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESSTTSMKIEAKELKGAHIFLDMVSVGATINI 172
Cdd:cd01555 81 MRASILVLGPLLARFGEARVSLPGGCAIGARPVDLHLKGLEALGAKIEIEDGYVEAKAAGRLKGARIYLDFPSVGATENI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 173 MLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGTYMCIAAACGENV 252
Cdd:cd01555 161 MMAAVLAEGTTVIENAAREPEIVDLANFLNKMGAKIEGAGTDTIRIEGVERLHGAEHTVIPDRIEAGTFLVAAAITGGDI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 253 ILNNIVPKHVETLTAKFSELGVNVDVRDERIRI-NNNAPYQFVDIKTLVYPGFATDLQQPITPLLFMANGPSFVTDTIYP 331
Cdd:cd01555 241 TVENVIPEHLEAVLAKLREMGAKIEIGEDGIRVdGDGGRLKAVDIETAPYPGFPTDLQAQFMALLTQAEGTSVITETIFE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 332 ERFKHVEELKRMGANIEVDEGTATIK-PSTLHGADVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRGYTDIVEHLKAL 410
Cdd:cd01555 321 NRFMHVDELNRMGADIKVEGNTAIIRgVTKLSGAPVMATDLRAGAALVLAGLAAEGETIISNIYHIDRGYERIEEKLRAL 400
|
|
| murA |
TIGR01072 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; [Cell envelope, Biosynthesis and ... |
3-415 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 162190 [Multi-domain] Cd Length: 416 Bit Score: 530.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 3 QEVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKASLNGTELEVDTTEIQN 82
Cdd:TIGR01072 1 MDKLVVEGGKPLSGEVTISGAKNAALPIIAATLLTDEPVTLTNVPDLSDVKTTLDLLRNLGARVERDNNTLEINTPNINS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 83 AALPNNKVESLRASYYMMGTMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEID-ESSTTSMKIEAKeLKGAHIFL 161
Cdd:TIGR01072 81 TEAPYELVRKMRASILVLGPLLARFGKAVVSLPGGCAIGARPVDLHLKGLKALGAEIViEDGYVYASAKGR-LVGAHIVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 162 DMVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGTY 241
Cdd:TIGR01072 160 DKVSVGATENIIMAAVLAEGTTVIENAAREPEIVDLCEFLNKMGAKITGAGSNTITIEGVEKLHGTEHSVIPDRIEAGTF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 242 MCIAAACGENVILNNIVPKHVETLTAKFSELGVNVDVRDERIRINNNAP-YQFVDIKTLVYPGFATDLQQPITPLLFMAN 320
Cdd:TIGR01072 240 LVAAAITGGEITIKNVRPDHLRAVLAKLREIGAEVEVDENGIRVDMRQKrLKAVDIETLPYPGFPTDLQAQFMALLSQAE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 321 GPSFVTDTIYPERFKHVEELKRMGANIEVDEGTATIK-PSTLHGADVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRG 399
Cdd:TIGR01072 320 GTSVITETVFENRFMHVDELIRMGANIKLEGNTAVIHgVEQLSGAEVMATDLRAGAALVLAGLVAEGETIVHNVYHLDRG 399
|
410
....*....|....*.
gi 616915692 400 YTDIVEHLKALGADIW 415
Cdd:TIGR01072 400 YEDLEEKLRALGAKIE 415
|
|
| EPSP_synthase |
pfam00275 |
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); |
9-407 |
6.31e-89 |
|
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase);
Pssm-ID: 395213 Cd Length: 415 Bit Score: 275.72 E-value: 6.31e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 9 RGGRTLNGEVNISG-AKNSAVAIIPATLLAqGHVKLEGLPQISDVKTLVSLLEDL---NIKASLNGTELEVDTTEIQNAA 84
Cdd:pfam00275 1 TGGSRLSGEVKIPGsKSNSHRALILAALAA-GESTITNLLDSDDTLTMLEALRALgaeIIKLDDEKSVVIVEGLGGSFEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 85 lPNNKVESLRASYYMMGTMLGRF--KKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESS---TTSMKIEAKELKGAHI 159
Cdd:pfam00275 80 -PEDLVLDMGNSGTALRPLTGRLalQSGEVVLPGDCSIGKRPMDRLLDALRQLGAEIEGREgynYAPLKVRGLRLGGIHI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 160 FLDMVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTST-IKINGVKELHGSEYQVIPDRIEA 238
Cdd:pfam00275 159 DGDVSSQFVTSLLMLAALLAEGTTTIENLASEPYIDDTENMLKKFGAKIEGSGTELsITVKGGEKLPGQEYRVEGDRSSA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 239 GTYMCIAAACGENVILNNIVPKHVETLTA---KFSELGVNVDVRDERIRINNNAPYQF--VDIKTLVYPGFATDLQQPIT 313
Cdd:pfam00275 239 AYFLVAAAITGGTVTVENVGINSLQGDEAlleILEKMGAEITQEEDADIVVGPPGLRGkaVDIRTAPDPAPTTAVLAAFA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 314 PLLFMANGPSFVTDTIYPERFKHVEELKRMGANIEVDEGTATIKPST--LHGADVYAS-DLRAGACLIIAGLIAEGVTTI 390
Cdd:pfam00275 319 EGTTRIEGISELRVKETDRLFAMATELRRLGADVEELPDGLIIIPAVkeLKGAEVDSYgDHRIAMALALAGLVAEGETII 398
|
410
....*....|....*..
gi 616915692 391 YNVKHIYRGYTDIVEHL 407
Cdd:pfam00275 399 DDIECTDRSFPDFEEKL 415
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK12830 |
PRK12830 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed |
3-419 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed
Pssm-ID: 183779 Cd Length: 417 Bit Score: 744.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 3 QEVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKASLNGTELEVDTTEIQN 82
Cdd:PRK12830 1 MEKIVINGGKPLSGEVTISGAKNSAVALIPAAILADGPVTLDGVPDISDVHSLVDILEELGGKVKRDGDTLEIDPTGIQS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 83 AALPNNKVESLRASYYMMGTMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESSTtSMKIEAKELKGAHIFLD 162
Cdd:PRK12830 81 MPLPNGKVKSLRASYYFMGALLGRFKKAVVGLPGGCDLGPRPIDQHIKGFEALGAEVTNEGG-AIYLKADELKGAHIYLD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 163 MVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGTYM 242
Cdd:PRK12830 160 VVSVGATINIMLAAVKAKGRTVIENAAKEPEIIDVATLLNNMGANIKGAGTDVIRIEGVDELHGCRHTVIPDRIEAGTYM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 243 CIAAACGENVILNNIVPKHVETLTAKFSELGVNVDVRDERIRINNNAPYQFVDIKTLVYPGFATDLQQPITPLLFMANGP 322
Cdd:PRK12830 240 ILAAACGGGVTINNVIPEHLESFIAKLEEMGVRVEVNEDSIFVEKQGNLKAVDIKTLPYPGFATDLQQPLTPLLLKANGR 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 323 SFVTDTIYPERFKHVEELKRMGANIEVDEGTATIK-PSTLHGADVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRGYT 401
Cdd:PRK12830 320 SVVTDTIYEKRFKHVDELKRMGANIKVEGRSAIITgPSKLTGAKVKATDLRAGAALVIAGLMAEGVTEITNIEHIDRGYS 399
|
410
....*....|....*...
gi 616915692 402 DIVEHLKALGADIWTETV 419
Cdd:PRK12830 400 NIIEKLKALGADIWREED 417
|
|
| MurA |
COG0766 |
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; ... |
4-415 |
0e+00 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylglucosamine enolpyruvyl transferase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440529 Cd Length: 416 Bit Score: 624.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 4 EVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKAS-LNGTELEVDTTEIQN 82
Cdd:COG0766 2 DKLIIEGGKPLSGEVRISGAKNAALPILAAALLTDGPVTLRNVPDLSDVRTMLELLESLGVKVErDDGGTLTIDASNINS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 83 AALPNNKVESLRASYYMMGTMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESSTtSMKIEAKELKGAHIFLD 162
Cdd:COG0766 82 TEAPYELVRKMRASILVLGPLLARFGEARVSLPGGCAIGARPIDLHLKGLEALGAEIEIEHG-YIEARAGRLKGARIYLD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 163 MVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGTYM 242
Cdd:COG0766 161 FPSVGATENIMMAAVLAEGTTVIENAAREPEIVDLANFLNAMGAKIEGAGTDTITIEGVEKLHGAEHTVIPDRIEAGTFL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 243 CIAAACGENVILNNIVPKHVETLTAKFSELGVNVDVRDERIRINNNAPYQFVDIKTLVYPGFATDLQQPITPLLFMANGP 322
Cdd:COG0766 241 VAAAITGGDVTVKNVIPEHLEAVLAKLREAGVEIEEGDDGIRVRGPGRLKAVDIKTAPYPGFPTDLQAQFMALLTQAEGT 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 323 SFVTDTIYPERFKHVEELKRMGANIEVDEGTATIK-PSTLHGADVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRGYT 401
Cdd:COG0766 321 SVITETVFENRFMHVDELNRMGADIKLDGHTAIVRgVTKLSGAPVMATDLRAGAALVLAGLAAEGETVIDNIYHIDRGYE 400
|
410
....*....|....
gi 616915692 402 DIVEHLKALGADIW 415
Cdd:COG0766 401 NLEEKLRALGADIE 414
|
|
| UdpNAET |
cd01555 |
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the ... |
14-410 |
0e+00 |
|
UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-(1-carboxyvinyl)-D-glucosamine. This enzyme is of interest as a potential target for anti-bacterial agents. The only other known enolpyruvyl transferase is the related 5-enolpyruvylshikimate-3-phosphate synthase.
Pssm-ID: 238796 Cd Length: 400 Bit Score: 591.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 14 LNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKASLNGT-ELEVDTTEIQNAALPNNKVES 92
Cdd:cd01555 1 LSGEVRISGAKNAALPILAAALLTDEPVTLRNVPDLLDVETMIELLRSLGAKVEFEGEnTLVIDASNINSTEAPYELVRK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 93 LRASYYMMGTMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESSTTSMKIEAKELKGAHIFLDMVSVGATINI 172
Cdd:cd01555 81 MRASILVLGPLLARFGEARVSLPGGCAIGARPVDLHLKGLEALGAKIEIEDGYVEAKAAGRLKGARIYLDFPSVGATENI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 173 MLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGTYMCIAAACGENV 252
Cdd:cd01555 161 MMAAVLAEGTTVIENAAREPEIVDLANFLNKMGAKIEGAGTDTIRIEGVERLHGAEHTVIPDRIEAGTFLVAAAITGGDI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 253 ILNNIVPKHVETLTAKFSELGVNVDVRDERIRI-NNNAPYQFVDIKTLVYPGFATDLQQPITPLLFMANGPSFVTDTIYP 331
Cdd:cd01555 241 TVENVIPEHLEAVLAKLREMGAKIEIGEDGIRVdGDGGRLKAVDIETAPYPGFPTDLQAQFMALLTQAEGTSVITETIFE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 332 ERFKHVEELKRMGANIEVDEGTATIK-PSTLHGADVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRGYTDIVEHLKAL 410
Cdd:cd01555 321 NRFMHVDELNRMGADIKVEGNTAIIRgVTKLSGAPVMATDLRAGAALVLAGLAAEGETIISNIYHIDRGYERIEEKLRAL 400
|
|
| PRK09369 |
PRK09369 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated |
4-415 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated
Pssm-ID: 236486 Cd Length: 417 Bit Score: 585.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 4 EVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKASLNGT-ELEVDTTEIQN 82
Cdd:PRK09369 2 DKLVIEGGKPLSGEVTISGAKNAALPILAASLLAEEPVTLTNVPDLSDVRTMIELLRSLGAKVEFDGNgTVTIDASNINN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 83 AALPNNKVESLRASYYMMGTMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESSTTsmkIEAK---ELKGAHI 159
Cdd:PRK09369 82 TEAPYELVKKMRASILVLGPLLARFGEAKVSLPGGCAIGARPVDLHLKGLEALGAEIEIEHGY---VEAKadgRLKGAHI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 160 FLDMVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAG 239
Cdd:PRK09369 159 VLDFPSVGATENILMAAVLAEGTTVIENAAREPEIVDLANFLNKMGAKISGAGTDTITIEGVERLHGAEHTVIPDRIEAG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 240 TYMCIAAACGENVILNNIVPKHVETLTAKFSELGVNVDVRDERIRINNNAPYQFVDIKTLVYPGFATDLQQPITPLLFMA 319
Cdd:PRK09369 239 TFLVAAAITGGDVTIRGARPEHLEAVLAKLREAGAEIEEGEDGIRVDMPGRLKAVDIKTAPYPGFPTDMQAQFMALLTQA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 320 NGPSFVTDTIYPERFKHVEELKRMGANIEVDEGTATIK-PSTLHGADVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYR 398
Cdd:PRK09369 319 EGTSVITETIFENRFMHVPELIRMGADIEVDGHTAVVRgVEKLSGAPVMATDLRASASLVLAGLVAEGTTIVDRIYHLDR 398
|
410
....*....|....*..
gi 616915692 399 GYTDIVEHLKALGADIW 415
Cdd:PRK09369 399 GYERIEEKLRALGADIE 415
|
|
| murA |
TIGR01072 |
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; [Cell envelope, Biosynthesis and ... |
3-415 |
0e+00 |
|
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 162190 [Multi-domain] Cd Length: 416 Bit Score: 530.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 3 QEVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKASLNGTELEVDTTEIQN 82
Cdd:TIGR01072 1 MDKLVVEGGKPLSGEVTISGAKNAALPIIAATLLTDEPVTLTNVPDLSDVKTTLDLLRNLGARVERDNNTLEINTPNINS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 83 AALPNNKVESLRASYYMMGTMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEID-ESSTTSMKIEAKeLKGAHIFL 161
Cdd:TIGR01072 81 TEAPYELVRKMRASILVLGPLLARFGKAVVSLPGGCAIGARPVDLHLKGLKALGAEIViEDGYVYASAKGR-LVGAHIVL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 162 DMVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGTY 241
Cdd:TIGR01072 160 DKVSVGATENIIMAAVLAEGTTVIENAAREPEIVDLCEFLNKMGAKITGAGSNTITIEGVEKLHGTEHSVIPDRIEAGTF 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 242 MCIAAACGENVILNNIVPKHVETLTAKFSELGVNVDVRDERIRINNNAP-YQFVDIKTLVYPGFATDLQQPITPLLFMAN 320
Cdd:TIGR01072 240 LVAAAITGGEITIKNVRPDHLRAVLAKLREIGAEVEVDENGIRVDMRQKrLKAVDIETLPYPGFPTDLQAQFMALLSQAE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 321 GPSFVTDTIYPERFKHVEELKRMGANIEVDEGTATIK-PSTLHGADVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRG 399
Cdd:TIGR01072 320 GTSVITETVFENRFMHVDELIRMGANIKLEGNTAVIHgVEQLSGAEVMATDLRAGAALVLAGLVAEGETIVHNVYHLDRG 399
|
410
....*....|....*.
gi 616915692 400 YTDIVEHLKALGADIW 415
Cdd:TIGR01072 400 YEDLEEKLRALGAKIE 415
|
|
| EPSP_synthase |
pfam00275 |
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); |
9-407 |
6.31e-89 |
|
EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase);
Pssm-ID: 395213 Cd Length: 415 Bit Score: 275.72 E-value: 6.31e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 9 RGGRTLNGEVNISG-AKNSAVAIIPATLLAqGHVKLEGLPQISDVKTLVSLLEDL---NIKASLNGTELEVDTTEIQNAA 84
Cdd:pfam00275 1 TGGSRLSGEVKIPGsKSNSHRALILAALAA-GESTITNLLDSDDTLTMLEALRALgaeIIKLDDEKSVVIVEGLGGSFEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 85 lPNNKVESLRASYYMMGTMLGRF--KKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESS---TTSMKIEAKELKGAHI 159
Cdd:pfam00275 80 -PEDLVLDMGNSGTALRPLTGRLalQSGEVVLPGDCSIGKRPMDRLLDALRQLGAEIEGREgynYAPLKVRGLRLGGIHI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 160 FLDMVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTST-IKINGVKELHGSEYQVIPDRIEA 238
Cdd:pfam00275 159 DGDVSSQFVTSLLMLAALLAEGTTTIENLASEPYIDDTENMLKKFGAKIEGSGTELsITVKGGEKLPGQEYRVEGDRSSA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 239 GTYMCIAAACGENVILNNIVPKHVETLTA---KFSELGVNVDVRDERIRINNNAPYQF--VDIKTLVYPGFATDLQQPIT 313
Cdd:pfam00275 239 AYFLVAAAITGGTVTVENVGINSLQGDEAlleILEKMGAEITQEEDADIVVGPPGLRGkaVDIRTAPDPAPTTAVLAAFA 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 314 PLLFMANGPSFVTDTIYPERFKHVEELKRMGANIEVDEGTATIKPST--LHGADVYAS-DLRAGACLIIAGLIAEGVTTI 390
Cdd:pfam00275 319 EGTTRIEGISELRVKETDRLFAMATELRRLGADVEELPDGLIIIPAVkeLKGAEVDSYgDHRIAMALALAGLVAEGETII 398
|
410
....*....|....*..
gi 616915692 391 YNVKHIYRGYTDIVEHL 407
Cdd:pfam00275 399 DDIECTDRSFPDFEEKL 415
|
|
| EPT-like |
cd01554 |
Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine ... |
14-410 |
1.05e-74 |
|
Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer.
Pssm-ID: 238795 Cd Length: 408 Bit Score: 238.66 E-value: 1.05e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 14 LNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKASLNGTELEVDTTEI---QNAALPNNKV 90
Cdd:cd01554 1 LHGIIRVPGDKSISHRSLIFASLAEGETKVYNILRGEDVLSTMQVLRDLGVEIEDKDGVITIQGVGMaglKAPQNALNLG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 91 ESLRASYYMMGTMLGRFKKcvIGLPGGCPLGPRPIDQHIKGFKALGAEI---DESSTTSMKIEAKELKGAHIFLDMVSVG 167
Cdd:cd01554 81 NSGTAIRLISGVLAGADFE--VELFGDDSLSKRPMDRVTLPLKKMGASIsgqEERDLPPLLKGGKNLGPIHYEDPIASAQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 168 ATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGTYMCIAAA 247
Cdd:cd01554 159 VKSALMFAALLAKGETVIIEAAKEPTINHTENMLQTFGGHISVQGTKKIVVQGPQKLTGQKYVVPGDISSAAFFLVAAAI 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 248 CGENVILNNIVPKHVET-LTAKFSELGVNVDVRDERIRINNNAPyQFVDIKTLVYPgFATDLQQPITPLLFMANGPSFVT 326
Cdd:cd01554 239 APGRLVLQNVGINETRTgIIDVLRAMGAKIEIGEDTISVESSDL-KATEICGALIP-RLIDELPIIALLALQAQGTTVIK 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 327 DTIYPE------RFKHVEELKRMGANIEVDEGTATIK-PSTLHGADVYA-SDLRAGACLIIAGLIAEGVTTIYNVKHIYR 398
Cdd:cd01554 317 DAEELKvketdrIFVVADELNSMGADIEPTADGMIIKgKEKLHGARVNTfGDHRIGMMTALAALVADGEVELDRAEAINT 396
|
410
....*....|..
gi 616915692 399 GYTDIVEHLKAL 410
Cdd:cd01554 397 SYPSFFDDLESL 408
|
|
| EPSP_synthase |
cd01556 |
EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase ... |
14-410 |
1.46e-22 |
|
EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form 5-enolpyruvylshkimate-3-phosphate (EPSP), an intermediate in the shikimate pathway leading to aromatic amino acid biosynthesis. The reaction is phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. It is found in bacteria and plants but not animals. The enzyme is the target of the widely used herbicide glyphosate, which has been shown to occupy the active site. In bacteria and plants, it is a single domain protein, while in fungi, the domain is found as part of a multidomain protein with functions that are all part of the shikimate pathway.
Pssm-ID: 238797 Cd Length: 409 Bit Score: 98.78 E-value: 1.46e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 14 LNGEVNISGAKN-SAVAIIPAtLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKASLNGTELEVDTTEIQNaaLPNNKV-- 90
Cdd:cd01556 1 LSGEITVPGSKSiSHRALLLA-ALAEGESRIENLLDSDDTLATLEALRALGAKIEEEGGTVEIVGGGGLG--LPPEAVld 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 91 --ESLRASYYMMGTMLGRFKKCVIGlpGGCPLGPRPIDQHIKGFKALGAEID--ESSTTSMKIEAKELKGAHIFLDM-VS 165
Cdd:cd01556 78 cgNSGTTMRLLTGLLALQGGDSVLT--GDESLRKRPMGRLVDALRQLGAEIEgrEGGGYPPLIGGGGLKGGEVEIPGaVS 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 166 ---VGAtinIMLAAVYATGQTVIENAAKEPEV-VDV-ANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDrIEAGT 240
Cdd:cd01556 156 sqfKSA---LLLAAPLAEGPTTIIIGELESKPyIDHtERMLRAFGAEVEVDGYRTITVKGGQKYKGPEYTVEGD-ASSAA 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 241 YMcIAAAC--GENVILNNIVPKHVETLTAK-FSELGVNVDVRDER-IRINNNAPYQFVDIKtlvyPGFATDLQQPITPLL 316
Cdd:cd01556 232 FF-LAAAAitGSEIVIKNVGLNSGDTGIIDvLKEMGADIEIGNEDtVVVESGGKLKGIDID----GNDIPDEAPTLAVLA 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 317 FMANGPSFVTDtIYPERFKH-------VEELKRMGANIEVDEGTATIKPSTLHGADVYAS---DLRAGACLIIAGLIAEG 386
Cdd:cd01556 307 AFAEGPTRIRN-AAELRVKEsdriaamATELRKLGADVEETEDGLIIEGGPLKGAGVEVYtygDHRIAMSFAIAGLVAEG 385
|
410 420
....*....|....*....|....
gi 616915692 387 VTTIYNVKHIYRGYTDIVEHLKAL 410
Cdd:cd01556 386 GVTIEDPECVAKSFPNFFEDLESL 409
|
|
| AroA |
COG0128 |
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; ... |
4-410 |
6.81e-17 |
|
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; 5-enolpyruvylshikimate-3-phosphate synthase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439898 Cd Length: 421 Bit Score: 82.06 E-value: 6.81e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 4 EVIKIRGGRTLNGEVNISGAKN-SAVAIIPAtLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKAS-LNGTELEVdttEIQ 81
Cdd:COG0128 2 SSLTIAPPSPLKGTVRVPGSKSiSHRALLLA-ALAEGESTIRNLLESDDTLATLEALRALGAEIEeLDGGTLRV---TGV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 82 NAALPNNKV-----ESlrasyymmGTMLgRFkkcVIGLPGGCP----------LGPRPIDQHIKGFKALGAEIDESSTTS 146
Cdd:COG0128 78 GGGLKEPDAvldcgNS--------GTTM-RL---LTGLLALQPgevvltgdesLRKRPMGRLLDPLRQLGARIESRGGGY 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 147 --MKIEAKELKGAHIFLD-MVS---VGAtinIMLAAVYATGQTVIENAAKEPEV--VDVA-NFLTSMGANIKGAGTSTIK 217
Cdd:COG0128 146 lpLTIRGGPLKGGEYEIPgSASsqfKSA---LLLAGPLAEGGLEITVTGELESKpyRDHTeRMLRAFGVEVEVEGYRRFT 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 218 INGVKELHGSEYQVIPDRIEAGTYMCIAAACGENVILNNiVPKH--------VETLTakfsELGVNVDVRDERIRINNnA 289
Cdd:COG0128 223 VPGGQRYRPGDYTVPGDISSAAFFLAAAAITGSEVTVEG-VGLNstqgdtgiLDILK----EMGADIEIENDGITVRG-S 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 290 PYQFVDIKtlvyPGFATDLQQPITPLLFMANGPSFVTDtIYPERFKH-------VEELKRMGANIEVDEGTATIKPST-L 361
Cdd:COG0128 297 PLKGIDID----LSDIPDEAPTLAVLAAFAEGTTRIRG-AAELRVKEsdriaamATELRKLGADVEETEDGLIIEGGPkL 371
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 616915692 362 HGADV--YAsDLRAGACLIIAGLIAEGVTTIYNVKHIYRGYTDIVEHLKAL 410
Cdd:COG0128 372 KGAEVdsYG-DHRIAMAFAVAGLRAEGPVTIDDAECVAKSFPDFFELLESL 421
|
|
| aroA |
TIGR01356 |
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents ... |
16-413 |
3.54e-16 |
|
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents 3-phosphoshikimate-1-carboxyvinyltransferase (aroA), which catalyzes the sixth of seven steps in the shikimate pathway of the biosynthesis of chorimate. Chorismate is last common precursor of all three aromatic amino acids. Sequences scoring between the trusted and noise cutoffs include fragmentary and aberrant sequences in which generally well-conserved motifs are missing or altererd, but no example of a protein known to have a different function. [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273574 Cd Length: 409 Bit Score: 79.63 E-value: 3.54e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 16 GEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKASLNGTELEVD--TTEIQNAAL-PNNKVES 92
Cdd:TIGR01356 1 GEIRAPGSKSITHRALILAALAEGETRVRNLLRSEDTLATLDALRALGAKIEDGGEVAVIEgvGGKEPQAELdLGNSGTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 93 LRasyYMMGTM-LGRFKKCVIGLPGgcpLGPRPIDQHIKGFKALGAEIDESSTTS---MKIEAKeLKGAHIFLD-MVSVG 167
Cdd:TIGR01356 81 AR---LLTGVLaLADGEVVLTGDES---LRKRPMGRLVDALRQLGAEISSLEGGGslpLTISGP-LPGGIVYISgSASSQ 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 168 ATINIMLAAVYATGQT---VIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGTYMCI 244
Cdd:TIGR01356 154 YKSALLLAAPALQAVGitiVGEPLKSRPYIEITLDLLGSFGVEVERSDGRKIVVPGGQKYGPQGYDVPGDYSSAAFFLAA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 245 AAACGENVILNNIVPKHVET---LTAKFSELGVNVDVRDERIRINNNAPYQFV--DIKTLvypgfaTDLQQPITPLLFMA 319
Cdd:TIGR01356 234 AAITGGRVTLENLGINPTQGdkaIIIVLEEMGADIEVEEDDLIVEGASGLKGIkiDMDDM------IDELPTLAVLAAFA 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 320 NGPSFVTDtIYPERFKH-------VEELKRMGANIEVDEGTATIKPS-TLHGADVYA-SDLRAGACLIIAGLIAEGVTTI 390
Cdd:TIGR01356 308 EGVTRITG-AEELRVKEsdriaaiAEELRKLGVDVEEFEDGLYIRGKkELKGAVVDTfGDHRIAMAFAVAGLVAEGEVLI 386
|
410 420
....*....|....*....|...
gi 616915692 391 YNVKHIYRGYTDIVEHLKALGAD 413
Cdd:TIGR01356 387 DDPECVAKSFPSFFDVLERLGAN 409
|
|
| PRK02427 |
PRK02427 |
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional |
6-414 |
1.17e-15 |
|
3-phosphoshikimate 1-carboxyvinyltransferase; Provisional
Pssm-ID: 235037 [Multi-domain] Cd Length: 435 Bit Score: 78.26 E-value: 1.17e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 6 IKIRGGRTLNGEVNISGAKN-SAVAIIPAtLLAQGHVKLEGLPQISDVKTLVSLLEDLnikaslnGTELEVDTTEIQNAA 84
Cdd:PRK02427 5 LLIIPPSPLSGTVRVPGSKSiSHRALLLA-ALAEGETTITNLLRSEDTLATLNALRAL-------GVEIEDDEVVVEGVG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 85 LPNNKVeslRASYYMMG----TMlgRFkkcVIGLPGGCP----------LGPRPIDQHIKGFKALGAEID--ESSTTSMK 148
Cdd:PRK02427 77 GGGLKE---PEDVLDCGnsgtTM--RL---LTGLLALQPgevvltgdesLRKRPMGRLLDPLRQMGAKIEgrDEGYLPLT 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 149 IE-AKELKGAHIFLDM----VSvGAtinIMLAAVYATGQTVIEnaAKEPEV----VDV-ANFLTSMGANIK---GAGTST 215
Cdd:PRK02427 149 IRgGKKGGPIEYDGPVssqfVK-SL---LLLAPLFAEGDTETT--VIEPLPsrphTEItLRMLRAFGVEVEnveGWGYRR 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 216 IKINGVKELHGSEYQVIPDrIEAGTYMcIAAAC---GENVILNNiVPKH--------VETLTakfsELGVNVDVRDERIR 284
Cdd:PRK02427 223 IVIKGGQRLRGQDITVPGD-PSSAAFF-LAAAAitgGSEVTITN-VGLNstqggkaiIDVLE----KMGADIEIENEREG 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 285 INNNAPyqfVDIKTLVYPGF------ATDLQQPITPLLFMANGPSFVTDtIYPERFKH-------VEELKRMGANIEVDE 351
Cdd:PRK02427 296 GEPVGD---IRVRSSELKGIdidipdIIDEAPTLAVLAAFAEGTTVIRN-AEELRVKEtdriaamATELRKLGAEVEETE 371
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 616915692 352 GTATIKPSTLHGA-DVYAsDLRAGACLIIAGLIAEGVTTIYNVKHIYRGYTDIVEHLKALGADI 414
Cdd:PRK02427 372 DGLIITGGPLAGVvDSYG-DHRIAMAFAIAGLAAEGPVTIDDPECVAKSFPDFFEDLASLGANI 434
|
|
| AroA |
COG0128 |
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; ... |
129-418 |
2.20e-14 |
|
5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; 5-enolpyruvylshikimate-3-phosphate synthase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439898 Cd Length: 421 Bit Score: 74.35 E-value: 2.20e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 129 IKGFKALGAEIDESSTTSMKIE--AKELKGAHIFLDMVSVGATINIMLAAVYATGQTVI----ENAAKEP--EVVDVanf 200
Cdd:COG0128 54 LEALRALGAEIEELDGGTLRVTgvGGGLKEPDAVLDCGNSGTTMRLLTGLLALQPGEVVltgdESLRKRPmgRLLDP--- 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 201 LTSMGANIKGAGTST--IKINGVKeLHGSEY--------QVIpdrieagTYMCIAAACGEN----VILNNIVPK----HV 262
Cdd:COG0128 131 LRQLGARIESRGGGYlpLTIRGGP-LKGGEYeipgsassQFK-------SALLLAGPLAEGgleiTVTGELESKpyrdHT 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 263 ETLTAKFselGVNVDVRDE-RIRINNNAPYQFVDIKtlVyPG------FatdlqqpitpllFMANG---PSFVT------ 326
Cdd:COG0128 203 ERMLRAF---GVEVEVEGYrRFTVPGGQRYRPGDYT--V-PGdissaaF------------FLAAAaitGSEVTvegvgl 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 327 DTIYPE-RFkhVEELKRMGANIEVDEGTATIKPSTLHGADVyasDLRAGACLI----IAGLIAEGVTTIYNVKHIyRGY- 400
Cdd:COG0128 265 NSTQGDtGI--LDILKEMGADIEIENDGITVRGSPLKGIDI---DLSDIPDEAptlaVLAAFAEGTTRIRGAAEL-RVKe 338
|
330 340
....*....|....*....|..
gi 616915692 401 TD----IVEHLKALGADIwTET 418
Cdd:COG0128 339 SDriaaMATELRKLGADV-EET 359
|
|
| aroA |
TIGR01356 |
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents ... |
129-414 |
6.66e-13 |
|
3-phosphoshikimate 1-carboxyvinyltransferase; This model represents 3-phosphoshikimate-1-carboxyvinyltransferase (aroA), which catalyzes the sixth of seven steps in the shikimate pathway of the biosynthesis of chorimate. Chorismate is last common precursor of all three aromatic amino acids. Sequences scoring between the trusted and noise cutoffs include fragmentary and aberrant sequences in which generally well-conserved motifs are missing or altererd, but no example of a protein known to have a different function. [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273574 Cd Length: 409 Bit Score: 69.61 E-value: 6.66e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 129 IKGFKALGAEIdESSTTSMKIEAKELKGAHIFLDMVSVGATINIMLAAVYATGQTVI----ENAAKEPeVVDVANFLTSM 204
Cdd:TIGR01356 41 LDALRALGAKI-EDGGEVAVIEGVGGKEPQAELDLGNSGTTARLLTGVLALADGEVVltgdESLRKRP-MGRLVDALRQL 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 205 GANI---KGAGTSTIKINGVKELhGSEY-------QVIpdrieagTYMCIAAAC----GENVILNNIVPK-HVETLTAKF 269
Cdd:TIGR01356 119 GAEIsslEGGGSLPLTISGPLPG-GIVYisgsassQYK-------SALLLAAPAlqavGITIVGEPLKSRpYIEITLDLL 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 270 SELGVNVDVRDER-IRINNNAPYQFVDIKTlvyPGfatDLQQPITPLLFMANGPSFVT------DTIYPERfKHVEELKR 342
Cdd:TIGR01356 191 GSFGVEVERSDGRkIVVPGGQKYGPQGYDV---PG---DYSSAAFFLAAAAITGGRVTlenlgiNPTQGDK-AIIIVLEE 263
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 616915692 343 MGANIEVDEGTATIK-PSTLHGADVYASDLrAGACLIIAGL--IAEGVTTIYNVKHIYRGYTD----IVEHLKALGADI 414
Cdd:TIGR01356 264 MGADIEVEEDDLIVEgASGLKGIKIDMDDM-IDELPTLAVLaaFAEGVTRITGAEELRVKESDriaaIAEELRKLGVDV 341
|
|
| EPT_RTPC-like |
cd01553 |
This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate ... |
233-410 |
5.34e-10 |
|
This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while RTPC has 3 similar repeats with a 4th slightly different domain inserted between the 2nd and 3rd repeat. They evidently share the same active site location, although the catalytic residues differ.
Pssm-ID: 238794 Cd Length: 211 Bit Score: 58.83 E-value: 5.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 233 PDRIEAGTYMCIAAACGENVILNNIVP---------KHVETLTAKFSELGVNVDV---RDERIRINNNAPyQFVDIKTLV 300
Cdd:cd01553 8 GGGQILRSFLVLAAISGGPITVTGIRPdrakpgllrQHLTFLKALEKICGATVEGgelGSDRISFRPGTV-RGGDVRFAI 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616915692 301 YP-GFATDLQQPITPLLFMANGPSFVTDTIYPE----------RFKHVEELKRMGANIEVDEGTATIKPSTLHG------ 363
Cdd:cd01553 87 GSaGSCTDVLQTILPLLLFAKGPTRLTVTGGTDnpsappadfiRFVLEPELAKIGAHQEETLLRHGFYPAGGGVvatevs 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 616915692 364 --ADVYASDLRAGACLIIAGliaeGVTTIYNVKHIYRGYTDIVEHLKAL 410
Cdd:cd01553 167 pvEKLNTAQLRQLVLPMLLA----SGAVEFTVAHPSCHLLTNFAVLEAL 211
|
|
| |
