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Conserved domains on  [gi|2065892632|gb|KAG7655202|]
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CRAL/TRIO N-terminal domain [Arabidopsis suecica]

Protein Classification

SEC14 family lipid-binding protein( domain architecture ID 11280085)

SEC14 family lipid-binding protein contains a lipid-binding domain that is found in secretory proteins and in lipid regulated proteins

CATH:  3.40.525.10|1.10.8.20
Gene Ontology:  GO:1902936|GO:0008289
PubMed:  12767229|17428729

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SEC14 smart00516
Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p); Domain ...
 419-573 1.08e-32

Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p); Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p) and in RhoGAPs, RhoGEFs and the RasGAP, neurofibromin (NF1). Lipid-binding domain. The SEC14 domain of Dbl is known to associate with G protein beta/gamma subunits.


:

Pssm-ID: 214706 [Multi-domain]  Cd Length: 158  Bit Score: 123.56  E-value: 1.08e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  419 GVDKQGHVVIYSSYGEFQNKeifsdKEKLSKFLKWRIQFQEKCVRSlDFSPEAKSSFVFVSDFRNAPGlgQRALWQFIKR 498
Cdd:smart00516  14 GYDKDGRPVLIERAGRFDLK-----SVTLEELLRYLVYVLEKILQE-EKKTGGIEGFTVIFDLKGLSM--SNPDLSVLRK 85

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2065892632  499 AVKQFEDNYPEFVAKELFINVPWWYIPYYKTFGSIItSPRTRSKMVLSGPSkSAETIFKYVAPEVVPVKYGGLSK 573
Cdd:smart00516  86 ILKILQDHYPERLGKVYIINPPWFFRVLWKIIKPFL-DEKTREKIRFVGND-SKEELLEYIDKEQLPEELGGTLD 158
rne super family cl35953
ribonuclease E; Reviewed
 153-285 1.34e-08

ribonuclease E; Reviewed


The actual alignment was detected with superfamily member PRK10811:

Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 58.51  E-value: 1.34e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  153 AETKEEEKSAAPATVETKKEEVLAAPAP---IVAETKKEETPVAPAPVETKPAAPVVAETKKEEILPAAPVTTETKVEEK 229
Cdd:PRK10811   879 VEPVVSAPVVEAVAEVVEEPVVVAEPQPeevVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEPVVEPQDETAD 958

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2065892632  230 VVPVETTPAAPVTTETKEEEKAAPVTTETKEEEKAAPVETKKEEKATASTQVKRAS 285
Cdd:PRK10811   959 IEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATVEHN 1014
CRAL_TRIO_N smart01100
CRAL/TRIO, N-terminal domain;
357-389 2.31e-08

CRAL/TRIO, N-terminal domain;


:

Pssm-ID: 215024  Cd Length: 48  Bit Score: 50.63  E-value: 2.31e-08
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2065892632  357 PLLEDERSDVILLKFLRARDFKVKEAFTMLKNT 389
Cdd:smart01100  16 DLLPPRLDDAFLLRFLRARKFDVEKAKEMLEKY 48
PTZ00121 super family cl31754
MAEBL; Provisional
 17-449 2.75e-04

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 2.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632   17 KEETPAPVKEVEVPVTTEKAVAAPAPEATEEKVVSEVAVPETEvtAVKEEEVATGKEILQSESFK--EEGYLASELQEAE 94
Cdd:PTZ00121  1478 KAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEE--AKKADEAKKAEEAKKADEAKkaEEKKKADELKKAE 1555

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632   95 KNALAELKELVREAlnKREFTAPPPPPAPVKEEKVEEKKTEETEEKKEEVKTEEKSLEAETKEEEKSAAPatvETKKEEv 174
Cdd:PTZ00121  1556 ELKKAEEKKKAEEA--KKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE---ELKKAE- 1629

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  175 laapapivaETKKEETPVAPAPVETKPAApvvAETKKEEILPAAPVTTETKVEEKvvpvETTPAAPVTTETKEEEKAA-P 253
Cdd:PTZ00121  1630 ---------EEKKKVEQLKKKEAEEKKKA---EELKKAEEENKIKAAEEAKKAEE----DKKKAEEAKKAEEDEKKAAeA 1693

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  254 VTTETKEEEKAAPVETKKEEKATASTQVKRASKFIKdifvsvttsekkkeeekpavVTIEKAFAADQEEETKTVEAV--E 331
Cdd:PTZ00121  1694 LKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENK--------------------IKAEEAKKEAEEDKKKAEEAKkdE 1753

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  332 ESIVSITLPETAAYVEPEEVSIWGIPLLEDErSDVILLKFLRARDFKVKEAFTMLKNTVQWRKENKIDDLVSEDLEGSEF 411
Cdd:PTZ00121  1754 EEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE-LDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAI 1832

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 2065892632  412 EKLVFTHGVDK------QGHVVIYSSY-GEFQNKEIFSDKEKLSK 449
Cdd:PTZ00121  1833 KEVADSKNMQLeeadafEKHKFNKNNEnGEDGNKEADFNKEKDLK 1877
 
Name Accession Description Interval E-value
SEC14 smart00516
Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p); Domain ...
 419-573 1.08e-32

Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p); Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p) and in RhoGAPs, RhoGEFs and the RasGAP, neurofibromin (NF1). Lipid-binding domain. The SEC14 domain of Dbl is known to associate with G protein beta/gamma subunits.


Pssm-ID: 214706 [Multi-domain]  Cd Length: 158  Bit Score: 123.56  E-value: 1.08e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  419 GVDKQGHVVIYSSYGEFQNKeifsdKEKLSKFLKWRIQFQEKCVRSlDFSPEAKSSFVFVSDFRNAPGlgQRALWQFIKR 498
Cdd:smart00516  14 GYDKDGRPVLIERAGRFDLK-----SVTLEELLRYLVYVLEKILQE-EKKTGGIEGFTVIFDLKGLSM--SNPDLSVLRK 85

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2065892632  499 AVKQFEDNYPEFVAKELFINVPWWYIPYYKTFGSIItSPRTRSKMVLSGPSkSAETIFKYVAPEVVPVKYGGLSK 573
Cdd:smart00516  86 ILKILQDHYPERLGKVYIINPPWFFRVLWKIIKPFL-DEKTREKIRFVGND-SKEELLEYIDKEQLPEELGGTLD 158
SEC14 cd00170
Sec14p-like lipid-binding domain; Sec14p-like lipid-binding domains are found in secretory ...
 410-571 4.68e-27

Sec14p-like lipid-binding domain; Sec14p-like lipid-binding domains are found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to associate with G protein beta/gamma subunits.


Pssm-ID: 469559 [Multi-domain]  Cd Length: 156  Bit Score: 107.42  E-value: 4.68e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 410 EFEKLVFTHGVDKQGHVVIYSSYGEFQNKEIFSDKeklskFLKWRIQFQEKCVRSLDfspEAKSSFVFVSDFRNApGLGQ 489
Cdd:cd00170     7 LLGGIGYLGGRDKEGRPVLVFRAGWDPPKLLDLEE-----LLRYLVYLLEKALRELE---EQVEGFVVIIDLKGF-SLSN 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 490 RALWQFIKRAVKQFEDNYPEFVAKELFINVPWWYIPYYKTFGSIItSPRTRSKMVLSGPSKsaETIFKYVAPEVVPVKYG 569
Cdd:cd00170    78 LSDLSLLKKLLKILQDHYPERLKKIYIVNAPWIFSALWKIVKPFL-SEKTRKKIVFLGSDL--EELLEYIDPDQLPKELG 154


                  ..
gi 2065892632 570 GL 571
Cdd:cd00170   155 GT 156
CRAL_TRIO pfam00650
CRAL/TRIO domain;
413-570 5.19e-26

CRAL/TRIO domain;


Pssm-ID: 459890 [Multi-domain]  Cd Length: 151  Bit Score: 104.26  E-value: 5.19e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 413 KLVFTHGVDKQGHVVIYSSYGEFQNKEIFSDKeklskFLKWRIQFQEKCVRSLDFSPEAksSFVFVSDFRNAPGLG-QRA 491
Cdd:pfam00650   2 GKVYLHGRDKEGRPVLYLRLGRHDPKKSSEEE-----LVRFLVLVLERALLLMPEGQVE--GLTVIIDLKGLSLSNmDWW 74

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2065892632 492 LWQFIKRAVKQFEDNYPEFVAKELFINVPWWYIPYYKTFGSIItSPRTRSKMVLSGPSKSaETIFKYVAPEVVPVKYGG 570
Cdd:pfam00650  75 SISLLKKIIKILQDNYPERLGKILIVNAPWIFNTIWKLIKPFL-DPKTREKIVFLKNSNE-EELEKYIPPEQLPKEYGG 151
rne PRK10811
ribonuclease E; Reviewed
 153-285 1.34e-08

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 58.51  E-value: 1.34e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  153 AETKEEEKSAAPATVETKKEEVLAAPAP---IVAETKKEETPVAPAPVETKPAAPVVAETKKEEILPAAPVTTETKVEEK 229
Cdd:PRK10811   879 VEPVVSAPVVEAVAEVVEEPVVVAEPQPeevVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEPVVEPQDETAD 958

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2065892632  230 VVPVETTPAAPVTTETKEEEKAAPVTTETKEEEKAAPVETKKEEKATASTQVKRAS 285
Cdd:PRK10811   959 IEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATVEHN 1014
CRAL_TRIO_N smart01100
CRAL/TRIO, N-terminal domain;
357-389 2.31e-08

CRAL/TRIO, N-terminal domain;


Pssm-ID: 215024  Cd Length: 48  Bit Score: 50.63  E-value: 2.31e-08
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2065892632  357 PLLEDERSDVILLKFLRARDFKVKEAFTMLKNT 389
Cdd:smart01100  16 DLLPPRLDDAFLLRFLRARKFDVEKAKEMLEKY 48
CRAL_TRIO_N pfam03765
CRAL/TRIO, N-terminal domain; This all-alpha domain is found to the N-terminus of pfam00650.
 347-388 1.99e-07

CRAL/TRIO, N-terminal domain; This all-alpha domain is found to the N-terminus of pfam00650.


Pssm-ID: 461043  Cd Length: 53  Bit Score: 48.04  E-value: 1.99e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2065892632 347 EPEEVSIWgipLLEDERSDVILLKFLRARDFKVKEAFTMLKN 388
Cdd:pfam03765  15 ETDREKFW---LTREDHDDVCLLRFLRARKWDVEKAIKMLED 53
DUF6721 pfam20481
Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. ...
 188-277 1.77e-04

Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is typically a 100 amino acids in length.


Pssm-ID: 466630 [Multi-domain]  Cd Length: 96  Bit Score: 40.83  E-value: 1.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 188 EETPVAPAPVETKPAAPVvaETKKEEILPAAPVTTETKVEEKVVPVETT-----PAAPVTTETKEEEKAAPVTTETKEEE 262
Cdd:pfam20481   1 SSIPIDNKTNGTASSIPV--DSKNEETASSIPIDSTNNETASSIPIDNKttetaSSIPIDSSNSETAASIPIDNTNNSTA 78

                          90
                  ....*....|....*
gi 2065892632 263 KAAPVETKKEEKATA 277
Cdd:pfam20481  79 SSIPIDNKTSETASS 93
PTZ00121 PTZ00121
MAEBL; Provisional
 17-449 2.75e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 2.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632   17 KEETPAPVKEVEVPVTTEKAVAAPAPEATEEKVVSEVAVPETEvtAVKEEEVATGKEILQSESFK--EEGYLASELQEAE 94
Cdd:PTZ00121  1478 KAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEE--AKKADEAKKAEEAKKADEAKkaEEKKKADELKKAE 1555

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632   95 KNALAELKELVREAlnKREFTAPPPPPAPVKEEKVEEKKTEETEEKKEEVKTEEKSLEAETKEEEKSAAPatvETKKEEv 174
Cdd:PTZ00121  1556 ELKKAEEKKKAEEA--KKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE---ELKKAE- 1629

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  175 laapapivaETKKEETPVAPAPVETKPAApvvAETKKEEILPAAPVTTETKVEEKvvpvETTPAAPVTTETKEEEKAA-P 253
Cdd:PTZ00121  1630 ---------EEKKKVEQLKKKEAEEKKKA---EELKKAEEENKIKAAEEAKKAEE----DKKKAEEAKKAEEDEKKAAeA 1693

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  254 VTTETKEEEKAAPVETKKEEKATASTQVKRASKFIKdifvsvttsekkkeeekpavVTIEKAFAADQEEETKTVEAV--E 331
Cdd:PTZ00121  1694 LKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENK--------------------IKAEEAKKEAEEDKKKAEEAKkdE 1753

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  332 ESIVSITLPETAAYVEPEEVSIWGIPLLEDErSDVILLKFLRARDFKVKEAFTMLKNTVQWRKENKIDDLVSEDLEGSEF 411
Cdd:PTZ00121  1754 EEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE-LDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAI 1832

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 2065892632  412 EKLVFTHGVDK------QGHVVIYSSY-GEFQNKEIFSDKEKLSK 449
Cdd:PTZ00121  1833 KEVADSKNMQLeeadafEKHKFNKNNEnGEDGNKEADFNKEKDLK 1877
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 176-277 4.85e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 39.83  E-value: 4.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 176 AAPAPIVAETKKEETPVAPAPVETKPAAPVvAETKKEEILPAAPVTTETKVE-EKVVPVETTPAAPVTTETKEEEKAAPV 254
Cdd:COG3266   263 SASAPATTSLGEQQEVSLPPAVAAQPAAAA-AAQPSAVALPAAPAAAAAAAApAEAAAPQPTAAKPVVTETAAPAAPAPE 341

                          90       100
                  ....*....|....*....|...
gi 2065892632 255 TTETKEEEKAAPVETKKEEKATA 277
Cdd:COG3266   342 AAAAAAAPAAPAVAKKLAADEQW 364
 
Name Accession Description Interval E-value
SEC14 smart00516
Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p); Domain ...
 419-573 1.08e-32

Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p); Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p) and in RhoGAPs, RhoGEFs and the RasGAP, neurofibromin (NF1). Lipid-binding domain. The SEC14 domain of Dbl is known to associate with G protein beta/gamma subunits.


Pssm-ID: 214706 [Multi-domain]  Cd Length: 158  Bit Score: 123.56  E-value: 1.08e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  419 GVDKQGHVVIYSSYGEFQNKeifsdKEKLSKFLKWRIQFQEKCVRSlDFSPEAKSSFVFVSDFRNAPGlgQRALWQFIKR 498
Cdd:smart00516  14 GYDKDGRPVLIERAGRFDLK-----SVTLEELLRYLVYVLEKILQE-EKKTGGIEGFTVIFDLKGLSM--SNPDLSVLRK 85

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2065892632  499 AVKQFEDNYPEFVAKELFINVPWWYIPYYKTFGSIItSPRTRSKMVLSGPSkSAETIFKYVAPEVVPVKYGGLSK 573
Cdd:smart00516  86 ILKILQDHYPERLGKVYIINPPWFFRVLWKIIKPFL-DEKTREKIRFVGND-SKEELLEYIDKEQLPEELGGTLD 158
SEC14 cd00170
Sec14p-like lipid-binding domain; Sec14p-like lipid-binding domains are found in secretory ...
 410-571 4.68e-27

Sec14p-like lipid-binding domain; Sec14p-like lipid-binding domains are found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to associate with G protein beta/gamma subunits.


Pssm-ID: 469559 [Multi-domain]  Cd Length: 156  Bit Score: 107.42  E-value: 4.68e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 410 EFEKLVFTHGVDKQGHVVIYSSYGEFQNKEIFSDKeklskFLKWRIQFQEKCVRSLDfspEAKSSFVFVSDFRNApGLGQ 489
Cdd:cd00170     7 LLGGIGYLGGRDKEGRPVLVFRAGWDPPKLLDLEE-----LLRYLVYLLEKALRELE---EQVEGFVVIIDLKGF-SLSN 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 490 RALWQFIKRAVKQFEDNYPEFVAKELFINVPWWYIPYYKTFGSIItSPRTRSKMVLSGPSKsaETIFKYVAPEVVPVKYG 569
Cdd:cd00170    78 LSDLSLLKKLLKILQDHYPERLKKIYIVNAPWIFSALWKIVKPFL-SEKTRKKIVFLGSDL--EELLEYIDPDQLPKELG 154


                  ..
gi 2065892632 570 GL 571
Cdd:cd00170   155 GT 156
CRAL_TRIO pfam00650
CRAL/TRIO domain;
413-570 5.19e-26

CRAL/TRIO domain;


Pssm-ID: 459890 [Multi-domain]  Cd Length: 151  Bit Score: 104.26  E-value: 5.19e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 413 KLVFTHGVDKQGHVVIYSSYGEFQNKEIFSDKeklskFLKWRIQFQEKCVRSLDFSPEAksSFVFVSDFRNAPGLG-QRA 491
Cdd:pfam00650   2 GKVYLHGRDKEGRPVLYLRLGRHDPKKSSEEE-----LVRFLVLVLERALLLMPEGQVE--GLTVIIDLKGLSLSNmDWW 74

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2065892632 492 LWQFIKRAVKQFEDNYPEFVAKELFINVPWWYIPYYKTFGSIItSPRTRSKMVLSGPSKSaETIFKYVAPEVVPVKYGG 570
Cdd:pfam00650  75 SISLLKKIIKILQDNYPERLGKILIVNAPWIFNTIWKLIKPFL-DPKTREKIVFLKNSNE-EELEKYIPPEQLPKEYGG 151
rne PRK10811
ribonuclease E; Reviewed
 153-285 1.34e-08

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 58.51  E-value: 1.34e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  153 AETKEEEKSAAPATVETKKEEVLAAPAP---IVAETKKEETPVAPAPVETKPAAPVVAETKKEEILPAAPVTTETKVEEK 229
Cdd:PRK10811   879 VEPVVSAPVVEAVAEVVEEPVVVAEPQPeevVVVETTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEPVVEPQDETAD 958

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 2065892632  230 VVPVETTPAAPVTTETKEEEKAAPVTTETKEEEKAAPVETKKEEKATASTQVKRAS 285
Cdd:PRK10811   959 IEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATVEHN 1014
CRAL_TRIO_N smart01100
CRAL/TRIO, N-terminal domain;
357-389 2.31e-08

CRAL/TRIO, N-terminal domain;


Pssm-ID: 215024  Cd Length: 48  Bit Score: 50.63  E-value: 2.31e-08
                           10        20        30
                   ....*....|....*....|....*....|...
gi 2065892632  357 PLLEDERSDVILLKFLRARDFKVKEAFTMLKNT 389
Cdd:smart01100  16 DLLPPRLDDAFLLRFLRARKFDVEKAKEMLEKY 48
rne PRK10811
ribonuclease E; Reviewed
 165-354 4.29e-08

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 56.59  E-value: 4.29e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  165 ATVETKKEEVLAAPAPIVAetkkeETPVAPAPVETKPAAPVVAETKKEEilpaAPVTTETKVEEKVVPVETTP----AAP 240
Cdd:PRK10811   853 VQVEEQREAEEVQVQPVVA-----EVPVAAAVEPVVSAPVVEAVAEVVE----EPVVVAEPQPEEVVVVETTHpeviAAP 923

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  241 VTTETKE-EEKAAPVTTETKEEekAAPVETKKEEKATASTQVKRASKFIKDifVSVTTSEKKKEEEKPAVVTIEKAFAAD 319
Cdd:PRK10811   924 VTEQPQViTESDVAVAQEVAEH--AEPVVEPQDETADIEEAAETAEVVVAE--PEVVAQPAAPVVAEVAAEVETVTAVEP 999

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 2065892632  320 QEEETKTVEAVEESIVSiTLPETAA----YV-EPEEVSIW 354
Cdd:PRK10811  1000 EVAPAQVPEATVEHNHA-TAPMTRApapeYVpEAPRHSDW 1038
CRAL_TRIO_N pfam03765
CRAL/TRIO, N-terminal domain; This all-alpha domain is found to the N-terminus of pfam00650.
 347-388 1.99e-07

CRAL/TRIO, N-terminal domain; This all-alpha domain is found to the N-terminus of pfam00650.


Pssm-ID: 461043  Cd Length: 53  Bit Score: 48.04  E-value: 1.99e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2065892632 347 EPEEVSIWgipLLEDERSDVILLKFLRARDFKVKEAFTMLKN 388
Cdd:pfam03765  15 ETDREKFW---LTREDHDDVCLLRFLRARKWDVEKAIKMLED 53
rne PRK10811
ribonuclease E; Reviewed
 152-287 9.94e-07

ribonuclease E; Reviewed


Pssm-ID: 236766 [Multi-domain]  Cd Length: 1068  Bit Score: 52.35  E-value: 9.94e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  152 EAETKEEEKSAAPATVETKKEEVLAAP------------APIVAETKKEETPVAPAPVETKPAAPVV---------AETK 210
Cdd:PRK10811   897 EPVVVAEPQPEEVVVVETTHPEVIAAPvteqpqvitesdVAVAQEVAEHAEPVVEPQDETADIEEAAetaevvvaePEVV 976

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2065892632  211 KEEILPAAPVTTETKVEEKVVPVETTPAAPVTTETKEEEKAAPVTTetkeeekaAPVETKKEEKATASTQVKRASKF 287
Cdd:PRK10811   977 AQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATVEHNHATAPMTR--------APAPEYVPEAPRHSDWQRPTFAF 1045
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 159-265 3.87e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 46.73  E-value: 3.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 159 EKSAAPATVETKKEEVLAAPAPiVAETKKEETPVAPAPVETKPAAPVVAETKKEEILPAAPVTTETKVEEKVVPVETTPA 238
Cdd:PRK14950  357 EALLVPVPAPQPAKPTAAAPSP-VRPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAPKLTRAA 435

                          90       100
                  ....*....|....*....|....*..
gi 2065892632 239 APVttetkEEEKAAPVTTETKEEEKAA 265
Cdd:PRK14950  436 IPV-----DEKPKYTPPAPPKEEEKAL 457
DUF6721 pfam20481
Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. ...
 188-277 1.77e-04

Domain of unknown function (DUF6721); This presumed domain is functionally uncharacterized. This domain family is found in eukaryotes, and is typically a 100 amino acids in length.


Pssm-ID: 466630 [Multi-domain]  Cd Length: 96  Bit Score: 40.83  E-value: 1.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 188 EETPVAPAPVETKPAAPVvaETKKEEILPAAPVTTETKVEEKVVPVETT-----PAAPVTTETKEEEKAAPVTTETKEEE 262
Cdd:pfam20481   1 SSIPIDNKTNGTASSIPV--DSKNEETASSIPIDSTNNETASSIPIDNKttetaSSIPIDSSNSETAASIPIDNTNNSTA 78

                          90
                  ....*....|....*
gi 2065892632 263 KAAPVETKKEEKATA 277
Cdd:pfam20481  79 SSIPIDNKTSETASS 93
PTZ00121 PTZ00121
MAEBL; Provisional
 17-449 2.75e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 2.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632   17 KEETPAPVKEVEVPVTTEKAVAAPAPEATEEKVVSEVAVPETEvtAVKEEEVATGKEILQSESFK--EEGYLASELQEAE 94
Cdd:PTZ00121  1478 KAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEE--AKKADEAKKAEEAKKADEAKkaEEKKKADELKKAE 1555

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632   95 KNALAELKELVREAlnKREFTAPPPPPAPVKEEKVEEKKTEETEEKKEEVKTEEKSLEAETKEEEKSAAPatvETKKEEv 174
Cdd:PTZ00121  1556 ELKKAEEKKKAEEA--KKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE---ELKKAE- 1629

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  175 laapapivaETKKEETPVAPAPVETKPAApvvAETKKEEILPAAPVTTETKVEEKvvpvETTPAAPVTTETKEEEKAA-P 253
Cdd:PTZ00121  1630 ---------EEKKKVEQLKKKEAEEKKKA---EELKKAEEENKIKAAEEAKKAEE----DKKKAEEAKKAEEDEKKAAeA 1693

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  254 VTTETKEEEKAAPVETKKEEKATASTQVKRASKFIKdifvsvttsekkkeeekpavVTIEKAFAADQEEETKTVEAV--E 331
Cdd:PTZ00121  1694 LKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENK--------------------IKAEEAKKEAEEDKKKAEEAKkdE 1753

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632  332 ESIVSITLPETAAYVEPEEVSIWGIPLLEDErSDVILLKFLRARDFKVKEAFTMLKNTVQWRKENKIDDLVSEDLEGSEF 411
Cdd:PTZ00121  1754 EEKKKIAHLKKEEEKKAEEIRKEKEAVIEEE-LDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAI 1832

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 2065892632  412 EKLVFTHGVDK------QGHVVIYSSY-GEFQNKEIFSDKEKLSK 449
Cdd:PTZ00121  1833 KEVADSKNMQLeeadafEKHKFNKNNEnGEDGNKEADFNKEKDLK 1877
PRK11907 PRK11907
bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;
174-271 1.12e-03

bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase;


Pssm-ID: 237019 [Multi-domain]  Cd Length: 814  Bit Score: 42.15  E-value: 1.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 174 VLAAPAPIVAETKKEETPVAPAPVETKPAAPVVAETKKEEILPAAPVTTETKVEEKVVP--VETTPAAPVTTETKEEEKA 251
Cdd:PRK11907   17 LLTASNPKLAQAEEIVTTTPATSTEAEQTTPVESDATEEADNTETPVAATTAAEAPSSSetAETSDPTSEATDTTTSEAR 96

                          90       100
                  ....*....|....*....|
gi 2065892632 252 APVTTETKEEEkaaPVETKK 271
Cdd:PRK11907   97 TVTPAATETSK---PVEGQT 113
PRK04654 PRK04654
sec-independent translocase; Provisional
 177-250 2.97e-03

sec-independent translocase; Provisional


Pssm-ID: 135173 [Multi-domain]  Cd Length: 214  Bit Score: 39.80  E-value: 2.97e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2065892632 177 APAPIVAETKkeetPVAPAPVETKPAAP--VVAETKKEEILPAAPVTTETkveekVVPVET-TPAAPVTTE-TKEEEK 250
Cdd:PRK04654  144 APAPVIAQAQ----PIAPAPHQTLVPAPhdTIVPAPHAAHLPSAPATPVS-----VAPVDAgTSASPTPSEpTKIQEK 212
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 161-277 3.85e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 40.62  E-value: 3.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 161 SAAPATVETKKEEVLAAPAPIVAETKKEETPVAPAPVETKP--AAPVVAETKKEEILPAAPVTTETKVEEKVVPVETTPA 238
Cdd:PRK07994  388 TAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQlqRAQGATKAKKSEPAAASRARPVNSALERLASVRPAPS 467

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2065892632 239 APVTTETKEEekAAPVTTETKEEEKAAPVETKKEEKATA 277
Cdd:PRK07994  468 ALEKAPAKKE--AYRWKATNPVEVKKEPVATPKALKKAL 504
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 176-266 4.00e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.47  E-value: 4.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 176 AAPAPIVAETKKEETPVAPAPVETKPAAPVVAETkkeeilPAAPVTTETKV----EEKVVPVETTPAAPVTTETKEEEKA 251
Cdd:PRK14951  369 AAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPA------PAAAPAAAASApaapPAAAPPAPVAAPAAAAPAAAPAAAP 442

                          90
                  ....*....|....*
gi 2065892632 252 APVTTETKEEEKAAP 266
Cdd:PRK14951  443 AAVALAPAPPAQAAP 457
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 176-277 4.85e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 39.83  E-value: 4.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 176 AAPAPIVAETKKEETPVAPAPVETKPAAPVvAETKKEEILPAAPVTTETKVE-EKVVPVETTPAAPVTTETKEEEKAAPV 254
Cdd:COG3266   263 SASAPATTSLGEQQEVSLPPAVAAQPAAAA-AAQPSAVALPAAPAAAAAAAApAEAAAPQPTAAKPVVTETAAPAAPAPE 341

                          90       100
                  ....*....|....*....|...
gi 2065892632 255 TTETKEEEKAAPVETKKEEKATA 277
Cdd:COG3266   342 AAAAAAAPAAPAVAKKLAADEQW 364
PRK05035 PRK05035
electron transport complex protein RnfC; Provisional
 152-331 6.15e-03

electron transport complex protein RnfC; Provisional


Pssm-ID: 235334 [Multi-domain]  Cd Length: 695  Bit Score: 39.93  E-value: 6.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 152 EAETKEEEKSAAPATVETKKEEVLAAPAPiVAETKKEETPVAPAPVETKPAAPVVAETKKEEILPAAPVTTETKVEEKVV 231
Cdd:PRK05035  466 KAAREARHKKAAEARAAKDKDAVAAALAR-VKAKKAAATQPIVIKAGARPDNSAVIAAREARKAQARARQAEKQAAAAAD 544

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 232 PVETTPAAPVT--TETKEEEKAAPVTTETKEEEKAAPVetkkeEKATASTQVKRASKFIKDIFVSVTTSEK-KKEEEKPA 308
Cdd:PRK05035  545 PKKAAVAAAIAraKAKKAAQQAANAEAEEEVDPKKAAV-----AAAIARAKAKKAAQQAASAEPEEQVAEVdPKKAAVAA 619

                         170       180
                  ....*....|....*....|...
gi 2065892632 309 VVTIEKAFAADQEEETKTVEAVE 331
Cdd:PRK05035  620 AIARAKAKKAEQQANAEPEEPVD 642
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 161-285 9.42e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 39.31  E-value: 9.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 161 SAAPATVETKKEEVLAAPAPIVAETKKEETPVAPAPVETKPAA---PVVAETKKEEILPAAPVTTETKVEEKVVPVETTP 237
Cdd:PRK14951  368 AAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAasaPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVAL 447

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 2065892632 238 AAPVTTETKEEEKAAPVTTETkeeEKAAPVETKKEEKATASTQVKRAS 285
Cdd:PRK14951  448 APAPPAQAAPETVAIPVRVAP---EPAVASAAPAPAAAPAAARLTPTE 492
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 174-265 9.70e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 39.02  E-value: 9.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065892632 174 VLAAPAPIVAETKKEETPVAPAPV--ETKPAAPV---VAETKKEEILPAAPVTTETkveekVVPVETTPAAPVTTETKEE 248
Cdd:PRK14950  379 VRPTPAPSTRPKAAAAANIPPKEPvrETATPPPVpprPVAPPVPHTPESAPKLTRA-----AIPVDEKPKYTPPAPPKEE 453

                          90
                  ....*....|....*..
gi 2065892632 249 EKAAPVTTETKEEEKAA 265
Cdd:PRK14950  454 EKALIADGDVLEQLEAI 470
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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