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Conserved domains on  [gi|2065807889|gb|KAG7576192|]
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Transposase MuDR plant [Arabidopsis thaliana x Arabidopsis arenosa]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DBD_Tnp_Mut pfam03108
MuDR family transposase; This region is found in plant proteins that are presumed to be the ...
 201-267 1.28e-32

MuDR family transposase; This region is found in plant proteins that are presumed to be the transposases for Mutator transposable elements. These transposons contain two ORFs. The molecular function of this region is unknown.


:

Pssm-ID: 427142  Cd Length: 67  Bit Score: 120.26  E-value: 1.28e-32
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2065807889 201 NTITGVGQRFKNVGEFREALRKYAIANQFGFRYKKNDSHRVTVKCKAEGCPWRIHASRLSTTQLICI 267
Cdd:pfam03108   1 GDTMRVGQCFPDLAEFRKALRKYAIARQFKFRLRKSDKDRFTVECEGEGCPWRIHASRRPETGLFEI 67
PB1_UP2 cd06410
Uncharacterized protein 2. The PB1 domain is a modular domain mediating specific ...
 9-99 1.88e-31

Uncharacterized protein 2. The PB1 domain is a modular domain mediating specific protein-protein interaction which play a role in many critical cell processes such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 interaction, which involves heterodimerization of two PB1 domains, is required for the formation of macromolecular signaling complexes ensuring specificity and fidelity during cellular signaling. The interaction between two PB1 domain depends on the type of PB1. There are three types of PB1 domains: type I which contains an OPCA motif, acidic aminoacid cluster, type II which contains a basic cluster, and type I/II which contains both an OPCA motif and a basic cluster. Interactions of PB1 domains with other protein domains have been described as noncanonical PB1-interactions.


:

Pssm-ID: 99731  Cd Length: 97  Bit Score: 118.09  E-value: 1.88e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065807889   9 ICMSGGEFQ-TEKGGSLSYKGGDAHAIDVDEQMKFIDFISEIGEMFNCDVRtVSLKYFLPDNKKT-LISISNDKDLKRMI 86
Cdd:cd06410     1 LCSYGGRILpRPPDGQLRYVGGETRIVSVDRSISFKELVSKLSELFGAGVV-VTLKYQLPDEDLDaLISVSNDEDLKNMM 79

                          90
                  ....*....|....*..
gi 2065807889  87 KFHE----NSNTADVYL 99
Cdd:cd06410    80 EEYDrlsgGSARLRVFL 96
MULE super family cl48097
MULE transposase domain; This domain was identified by Babu and colleagues.
 397-488 7.64e-12

MULE transposase domain; This domain was identified by Babu and colleagues.


The actual alignment was detected with superfamily member pfam10551:

Pssm-ID: 463145 [Multi-domain]  Cd Length: 98  Bit Score: 62.28  E-value: 7.64e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065807889 397 LVFLDSMPLKSKYQGTLLAATSVDGDDEVFPLAFAVVDAETDDNWEWFLLQLRSLL-----STPcyITFVADRQKNLQES 471
Cdd:pfam10551   1 VLLIDGTYKTNKYKMPLFTAVGVDHHGQSFPIAFGLVSNETEESFTWLFDQLIAFRecmsgLSP--QVIITDRDKALKNA 78

                          90
                  ....*....|....*..
gi 2065807889 472 IPKVFEKSFHAYCLRYL 488
Cdd:pfam10551  79 INLVFPEAQHRLCIFHI 95
ZnF_PMZ smart00575
plant mutator transposase zinc finger;
657-684 1.74e-08

plant mutator transposase zinc finger;


:

Pssm-ID: 128845  Cd Length: 28  Bit Score: 50.63  E-value: 1.74e-08
                           10        20
                   ....*....|....*....|....*...
gi 2065807889  657 CDCSCKGWQLTGLPCHHAVAVINYYGRN 684
Cdd:smart00575   1 KTCSCRKFQLSGIPCRHALAAAIHIGLS 28
 
Name Accession Description Interval E-value
DBD_Tnp_Mut pfam03108
MuDR family transposase; This region is found in plant proteins that are presumed to be the ...
 201-267 1.28e-32

MuDR family transposase; This region is found in plant proteins that are presumed to be the transposases for Mutator transposable elements. These transposons contain two ORFs. The molecular function of this region is unknown.


Pssm-ID: 427142  Cd Length: 67  Bit Score: 120.26  E-value: 1.28e-32
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2065807889 201 NTITGVGQRFKNVGEFREALRKYAIANQFGFRYKKNDSHRVTVKCKAEGCPWRIHASRLSTTQLICI 267
Cdd:pfam03108   1 GDTMRVGQCFPDLAEFRKALRKYAIARQFKFRLRKSDKDRFTVECEGEGCPWRIHASRRPETGLFEI 67
PB1_UP2 cd06410
Uncharacterized protein 2. The PB1 domain is a modular domain mediating specific ...
 9-99 1.88e-31

Uncharacterized protein 2. The PB1 domain is a modular domain mediating specific protein-protein interaction which play a role in many critical cell processes such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 interaction, which involves heterodimerization of two PB1 domains, is required for the formation of macromolecular signaling complexes ensuring specificity and fidelity during cellular signaling. The interaction between two PB1 domain depends on the type of PB1. There are three types of PB1 domains: type I which contains an OPCA motif, acidic aminoacid cluster, type II which contains a basic cluster, and type I/II which contains both an OPCA motif and a basic cluster. Interactions of PB1 domains with other protein domains have been described as noncanonical PB1-interactions.


Pssm-ID: 99731  Cd Length: 97  Bit Score: 118.09  E-value: 1.88e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065807889   9 ICMSGGEFQ-TEKGGSLSYKGGDAHAIDVDEQMKFIDFISEIGEMFNCDVRtVSLKYFLPDNKKT-LISISNDKDLKRMI 86
Cdd:cd06410     1 LCSYGGRILpRPPDGQLRYVGGETRIVSVDRSISFKELVSKLSELFGAGVV-VTLKYQLPDEDLDaLISVSNDEDLKNMM 79

                          90
                  ....*....|....*..
gi 2065807889  87 KFHE----NSNTADVYL 99
Cdd:cd06410    80 EEYDrlsgGSARLRVFL 96
PB1 smart00666
PB1 domain; Phox and Bem1p domain, present in many eukaryotic cytoplasmic signalling proteins. ...
 22-100 6.50e-14

PB1 domain; Phox and Bem1p domain, present in many eukaryotic cytoplasmic signalling proteins. The domain adopts a beta-grasp fold, similar to that found in ubiquitin and Ras-binding domains. A motif, variously termed OPR, PC and AID, represents the most conserved region of the majority of PB1 domains, and is necessary for PB1 domain function. This function is the formation of PB1 domain heterodimers, although not all PB1 domain pairs associate.


Pssm-ID: 214770  Cd Length: 81  Bit Score: 67.61  E-value: 6.50e-14
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2065807889   22 GSLSYkGGDAHAIDVDEQMKFIDFISEIGEMFNCDVRTVSLKYFlpDNKKTLISISNDKDLKRMIKFHENSNTADVYLL 100
Cdd:smart00666   4 VKLRY-GGETRRLSVPRDISFEDLRSKVAKRFGLDNQSFTLKYQ--DEDGDLVSLTSDEDLEEAIEEYDSLGSKKLRLH 79
MULE pfam10551
MULE transposase domain; This domain was identified by Babu and colleagues.
 397-488 7.64e-12

MULE transposase domain; This domain was identified by Babu and colleagues.


Pssm-ID: 463145 [Multi-domain]  Cd Length: 98  Bit Score: 62.28  E-value: 7.64e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065807889 397 LVFLDSMPLKSKYQGTLLAATSVDGDDEVFPLAFAVVDAETDDNWEWFLLQLRSLL-----STPcyITFVADRQKNLQES 471
Cdd:pfam10551   1 VLLIDGTYKTNKYKMPLFTAVGVDHHGQSFPIAFGLVSNETEESFTWLFDQLIAFRecmsgLSP--QVIITDRDKALKNA 78

                          90
                  ....*....|....*..
gi 2065807889 472 IPKVFEKSFHAYCLRYL 488
Cdd:pfam10551  79 INLVFPEAQHRLCIFHI 95
PB1 pfam00564
PB1 domain;
22-87 8.80e-10

PB1 domain;


Pssm-ID: 395447  Cd Length: 84  Bit Score: 55.76  E-value: 8.80e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2065807889  22 GSLSYKGGDAHAIDVDEQMKFIDFISEIGEMFNCDVRTVSLKYflPDNKKTLISISNDKDLKRMIK 87
Cdd:pfam00564   4 LKLRYGGGIRRFLSVSRGISFEELRALVEQRFGLDDVDFKLKY--PDEDGDLVSLTSDEDLEEALE 67
ZnF_PMZ smart00575
plant mutator transposase zinc finger;
657-684 1.74e-08

plant mutator transposase zinc finger;


Pssm-ID: 128845  Cd Length: 28  Bit Score: 50.63  E-value: 1.74e-08
                           10        20
                   ....*....|....*....|....*...
gi 2065807889  657 CDCSCKGWQLTGLPCHHAVAVINYYGRN 684
Cdd:smart00575   1 KTCSCRKFQLSGIPCRHALAAAIHIGLS 28
SWIM pfam04434
SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is ...
 642-682 4.17e-08

SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is predicted to be organized into two N-terminal beta-strands and a C-terminal alpha helix, thus possibly adopting a fold similar to that of the C2H2 zinc finger (pfam00096). SWIM is thought to be a versatile domain that can interact with DNA or proteins in different contexts.


Pssm-ID: 309540  Cd Length: 38  Bit Score: 49.72  E-value: 4.17e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 2065807889 642 FQVrgeTYELVNMAECDCSCKGWQLTGLPCHHAVAVINYYG 682
Cdd:pfam04434   1 YRV---QLDLDGLEKASCSCPDFQLNGIPCKHALAVLLALG 38
 
Name Accession Description Interval E-value
DBD_Tnp_Mut pfam03108
MuDR family transposase; This region is found in plant proteins that are presumed to be the ...
 201-267 1.28e-32

MuDR family transposase; This region is found in plant proteins that are presumed to be the transposases for Mutator transposable elements. These transposons contain two ORFs. The molecular function of this region is unknown.


Pssm-ID: 427142  Cd Length: 67  Bit Score: 120.26  E-value: 1.28e-32
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2065807889 201 NTITGVGQRFKNVGEFREALRKYAIANQFGFRYKKNDSHRVTVKCKAEGCPWRIHASRLSTTQLICI 267
Cdd:pfam03108   1 GDTMRVGQCFPDLAEFRKALRKYAIARQFKFRLRKSDKDRFTVECEGEGCPWRIHASRRPETGLFEI 67
PB1_UP2 cd06410
Uncharacterized protein 2. The PB1 domain is a modular domain mediating specific ...
 9-99 1.88e-31

Uncharacterized protein 2. The PB1 domain is a modular domain mediating specific protein-protein interaction which play a role in many critical cell processes such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 interaction, which involves heterodimerization of two PB1 domains, is required for the formation of macromolecular signaling complexes ensuring specificity and fidelity during cellular signaling. The interaction between two PB1 domain depends on the type of PB1. There are three types of PB1 domains: type I which contains an OPCA motif, acidic aminoacid cluster, type II which contains a basic cluster, and type I/II which contains both an OPCA motif and a basic cluster. Interactions of PB1 domains with other protein domains have been described as noncanonical PB1-interactions.


Pssm-ID: 99731  Cd Length: 97  Bit Score: 118.09  E-value: 1.88e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065807889   9 ICMSGGEFQ-TEKGGSLSYKGGDAHAIDVDEQMKFIDFISEIGEMFNCDVRtVSLKYFLPDNKKT-LISISNDKDLKRMI 86
Cdd:cd06410     1 LCSYGGRILpRPPDGQLRYVGGETRIVSVDRSISFKELVSKLSELFGAGVV-VTLKYQLPDEDLDaLISVSNDEDLKNMM 79

                          90
                  ....*....|....*..
gi 2065807889  87 KFHE----NSNTADVYL 99
Cdd:cd06410    80 EEYDrlsgGSARLRVFL 96
PB1 smart00666
PB1 domain; Phox and Bem1p domain, present in many eukaryotic cytoplasmic signalling proteins. ...
 22-100 6.50e-14

PB1 domain; Phox and Bem1p domain, present in many eukaryotic cytoplasmic signalling proteins. The domain adopts a beta-grasp fold, similar to that found in ubiquitin and Ras-binding domains. A motif, variously termed OPR, PC and AID, represents the most conserved region of the majority of PB1 domains, and is necessary for PB1 domain function. This function is the formation of PB1 domain heterodimers, although not all PB1 domain pairs associate.


Pssm-ID: 214770  Cd Length: 81  Bit Score: 67.61  E-value: 6.50e-14
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2065807889   22 GSLSYkGGDAHAIDVDEQMKFIDFISEIGEMFNCDVRTVSLKYFlpDNKKTLISISNDKDLKRMIKFHENSNTADVYLL 100
Cdd:smart00666   4 VKLRY-GGETRRLSVPRDISFEDLRSKVAKRFGLDNQSFTLKYQ--DEDGDLVSLTSDEDLEEAIEEYDSLGSKKLRLH 79
PB1 cd05992
The PB1 domain is a modular domain mediating specific protein-protein interactions which play ...
 24-99 1.56e-12

The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 interaction, which involves heterodimerization of two PB1 domain, is required for the formation of macromolecular signaling complexes ensuring specificity and fidelity during cellular signaling. The interaction between two PB1 domain depends on the type of PB1. There are three types of PB1 domains: type I which contains an OPCA motif, acidic aminoacid cluster, type II which contains a basic cluster, and type I/II which contains both an OPCA motif and a basic cluster. Interactions of PB1 domains with other protein domains have been described as a noncanonical PB1-interactions. The PB1 domain module is conserved in amoebas, fungi, animals, and plants.


Pssm-ID: 99716 [Multi-domain]  Cd Length: 81  Bit Score: 63.45  E-value: 1.56e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2065807889  24 LSYKGGDAHAIDVDEQMKFIDFISEIGEMFNCDVRTVSLKYflPDNKKTLISISNDKDLKRMIKFHENSNTADVYL 99
Cdd:cd05992     5 VKYGGEIRRFVVVSRSISFEDLRSKIAEKFGLDAVSFKLKY--PDEDGDLVTISSDEDLEEAIEEARRSGSKKLRL 78
MULE pfam10551
MULE transposase domain; This domain was identified by Babu and colleagues.
 397-488 7.64e-12

MULE transposase domain; This domain was identified by Babu and colleagues.


Pssm-ID: 463145 [Multi-domain]  Cd Length: 98  Bit Score: 62.28  E-value: 7.64e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2065807889 397 LVFLDSMPLKSKYQGTLLAATSVDGDDEVFPLAFAVVDAETDDNWEWFLLQLRSLL-----STPcyITFVADRQKNLQES 471
Cdd:pfam10551   1 VLLIDGTYKTNKYKMPLFTAVGVDHHGQSFPIAFGLVSNETEESFTWLFDQLIAFRecmsgLSP--QVIITDRDKALKNA 78

                          90
                  ....*....|....*..
gi 2065807889 472 IPKVFEKSFHAYCLRYL 488
Cdd:pfam10551  79 INLVFPEAQHRLCIFHI 95
PB1 pfam00564
PB1 domain;
22-87 8.80e-10

PB1 domain;


Pssm-ID: 395447  Cd Length: 84  Bit Score: 55.76  E-value: 8.80e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2065807889  22 GSLSYKGGDAHAIDVDEQMKFIDFISEIGEMFNCDVRTVSLKYflPDNKKTLISISNDKDLKRMIK 87
Cdd:pfam00564   4 LKLRYGGGIRRFLSVSRGISFEELRALVEQRFGLDDVDFKLKY--PDEDGDLVSLTSDEDLEEALE 67
ZnF_PMZ smart00575
plant mutator transposase zinc finger;
657-684 1.74e-08

plant mutator transposase zinc finger;


Pssm-ID: 128845  Cd Length: 28  Bit Score: 50.63  E-value: 1.74e-08
                           10        20
                   ....*....|....*....|....*...
gi 2065807889  657 CDCSCKGWQLTGLPCHHAVAVINYYGRN 684
Cdd:smart00575   1 KTCSCRKFQLSGIPCRHALAAAIHIGLS 28
SWIM pfam04434
SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is ...
 642-682 4.17e-08

SWIM zinc finger; This domain is found in bacterial, archaeal and eukaryotic proteins. It is predicted to be organized into two N-terminal beta-strands and a C-terminal alpha helix, thus possibly adopting a fold similar to that of the C2H2 zinc finger (pfam00096). SWIM is thought to be a versatile domain that can interact with DNA or proteins in different contexts.


Pssm-ID: 309540  Cd Length: 38  Bit Score: 49.72  E-value: 4.17e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 2065807889 642 FQVrgeTYELVNMAECDCSCKGWQLTGLPCHHAVAVINYYG 682
Cdd:pfam04434   1 YRV---QLDLDGLEKASCSCPDFQLNGIPCKHALAVLLALG 38
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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