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Conserved domains on  [gi|1980420102|gb|KAG2503795|]
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Sgt2p [Saccharomyces cerevisiae]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 13873705)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
41-221 6.60e-18

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 81.50  E-value: 6.60e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102  41 SEAFGFEREAVSGILGKSEFKGQHLADILNSASRVPESNKKDDAENVEINIPEDDAETKAK-AEDLKMQGNKAMANKDYE 119
Cdd:COG4785    11 ALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALALPDlAQLYYERGVAYDSLGDYD 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 120 LAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDI 199
Cdd:COG4785    91 LAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALEL 170

                         170       180
                  ....*....|....*....|....*....
gi 1980420102 200 EGDNATEAM-------KRDYESAKKKVEQ 221
Cdd:COG4785   171 DPNDPERALwlylaerKLDPEKALALLLE 199
SGTA_dimer pfam16546
Homodimerization domain of SGTA; SGTA_dimer is a short N-terminal domain at the start of SGTA ...
 7-71 2.64e-16

Homodimerization domain of SGTA; SGTA_dimer is a short N-terminal domain at the start of SGTA or small glutamine-rich tetratricopeptide repeat-containing proteins. It is the homodimerization domain of the SGTA, a heat-shock protein (HSP) co-chaperone involved in the targeting of tail-anchor membrane proteins to the endoplasmic reticulum. This N-terminal homodimerization domain mediates the association with a single copy of Get4 or Get5 proteins, providing a link to the rest of the GET pathway.


:

Pssm-ID: 465168  Cd Length: 64  Bit Score: 72.17  E-value: 2.64e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1980420102   7 EIAALIVNYFSSIVEKKEISEDGADSLNVAMDCISEAFGFEREAVSGIlgKSEFKGQHLADILNS 71
Cdd:pfam16546   2 RLALSIIDFLSTSLSDGTLSEDDAESLEVAIQCIAEAFEVDPDDEAAV--VKAFGGQSLLEIFEV 64
STI1 smart00727
Heat shock chaperonin-binding motif;
264-298 1.63e-03

Heat shock chaperonin-binding motif;


:

Pssm-ID: 128966  Cd Length: 41  Bit Score: 35.71  E-value: 1.63e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 1980420102  264 MNNPQLMQAAQKMMSNPgamQNIQKMMQ-DPSIRQM 298
Cdd:smart00727   8 LQNPQVQSLLQDMQQNP---DMLAQMLQeNPQLLQL 40
 
Name Accession Description Interval E-value
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
41-221 6.60e-18

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 81.50  E-value: 6.60e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102  41 SEAFGFEREAVSGILGKSEFKGQHLADILNSASRVPESNKKDDAENVEINIPEDDAETKAK-AEDLKMQGNKAMANKDYE 119
Cdd:COG4785    11 ALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALALPDlAQLYYERGVAYDSLGDYD 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 120 LAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDI 199
Cdd:COG4785    91 LAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALEL 170

                         170       180
                  ....*....|....*....|....*....
gi 1980420102 200 EGDNATEAM-------KRDYESAKKKVEQ 221
Cdd:COG4785   171 DPNDPERALwlylaerKLDPEKALALLLE 199
SGTA_dimer pfam16546
Homodimerization domain of SGTA; SGTA_dimer is a short N-terminal domain at the start of SGTA ...
 7-71 2.64e-16

Homodimerization domain of SGTA; SGTA_dimer is a short N-terminal domain at the start of SGTA or small glutamine-rich tetratricopeptide repeat-containing proteins. It is the homodimerization domain of the SGTA, a heat-shock protein (HSP) co-chaperone involved in the targeting of tail-anchor membrane proteins to the endoplasmic reticulum. This N-terminal homodimerization domain mediates the association with a single copy of Get4 or Get5 proteins, providing a link to the rest of the GET pathway.


Pssm-ID: 465168  Cd Length: 64  Bit Score: 72.17  E-value: 2.64e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1980420102   7 EIAALIVNYFSSIVEKKEISEDGADSLNVAMDCISEAFGFEREAVSGIlgKSEFKGQHLADILNS 71
Cdd:pfam16546   2 RLALSIIDFLSTSLSDGTLSEDDAESLEVAIQCIAEAFEVDPDDEAAV--VKAFGGQSLLEIFEV 64
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 102-240 1.09e-12

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 68.27  E-value: 1.09e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 102 AEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKY 181
Cdd:PLN03088    2 AKDLEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACM 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1980420102 182 AQGKPEEALEAYKKVLDIEGDNA--TEAMKRDYESAKKKVEQSLNLEKTVPEQSRDADVDA 240
Cdd:PLN03088   82 KLEEYQTAKAALEKGASLAPGDSrfTKLIKECDEKIAEEEKDLVQPVPSDLPSSVTAPPVE 142
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 77-190 2.52e-12

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 67.70  E-value: 2.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102  77 ESNKKDDAENVeINIPEDdaETKAKAEDLKMQGNKAMANKDYELAINKYTEAIKVLPtNAIYYANRAAAHSSLKEYDQAV 156
Cdd:TIGR00990 105 DELPEIDESSV-ANLSEE--ERKKYAAKLKEKGNKAYRNKDFNKAIKLYSKAIECKP-DPVYYSNRAACHNALGDWEKVV 180

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1980420102 157 KDAESAISIDPSYFRGYSRLGFAKYAQGKPEEAL 190
Cdd:TIGR00990 181 EDTTAALELDPDYSKALNRRANAYDGLGKYADAL 214
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 103-221 5.73e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 44.16  E-value: 5.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 103 EDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYfrgysrlGFAKY- 181
Cdd:cd24142     1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDG-------GYEKYl 73

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1980420102 182 --AQ-GKPEEALEAYKK---VLDIEGDNATEAMKRDYESAKKKVEQ 221
Cdd:cd24142    74 ylGQlSGGEEALQYYEKgieILEEELQALQAASAEAEEEAEELKRK 119
BTAD smart01043
Bacterial transcriptional activator domain; Found in the DNRI/REDD/AFSR family of regulators. ...
 142-208 1.04e-04

Bacterial transcriptional activator domain; Found in the DNRI/REDD/AFSR family of regulators. This region of AFSR along with the C terminal region is capable of independently directing actinorhodin production. This family contains TPR repeats.


Pssm-ID: 198111 [Multi-domain]  Cd Length: 145  Bit Score: 41.90  E-value: 1.04e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1980420102  142 RAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKV-------LDIEGDNATEAM 208
Cdd:smart01043  67 LAEALLALGRHEEALALLERLLALDPLRERLHRLLMRALYRAGRRAEALRAYRRLrrlladeLGVEPGPELRAL 140
TPR_1 pfam00515
Tetratricopeptide repeat;
136-169 1.93e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.17  E-value: 1.93e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1980420102 136 AIYYANRAAAHSSLKEYDQAVKDAESAISIDPSY 169
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
STI1 smart00727
Heat shock chaperonin-binding motif;
264-298 1.63e-03

Heat shock chaperonin-binding motif;


Pssm-ID: 128966  Cd Length: 41  Bit Score: 35.71  E-value: 1.63e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 1980420102  264 MNNPQLMQAAQKMMSNPgamQNIQKMMQ-DPSIRQM 298
Cdd:smart00727   8 LQNPQVQSLLQDMQQNP---DMLAQMLQeNPQLLQL 40
 
Name Accession Description Interval E-value
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
41-221 6.60e-18

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 81.50  E-value: 6.60e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102  41 SEAFGFEREAVSGILGKSEFKGQHLADILNSASRVPESNKKDDAENVEINIPEDDAETKAK-AEDLKMQGNKAMANKDYE 119
Cdd:COG4785    11 ALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALALPDlAQLYYERGVAYDSLGDYD 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 120 LAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDI 199
Cdd:COG4785    91 LAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALEL 170

                         170       180
                  ....*....|....*....|....*....
gi 1980420102 200 EGDNATEAM-------KRDYESAKKKVEQ 221
Cdd:COG4785   171 DPNDPERALwlylaerKLDPEKALALLLE 199
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
102-226 9.79e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.51  E-value: 9.79e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 102 AEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKY 181
Cdd:COG0457     8 AEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQ 87

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1980420102 182 AQGKPEEALEAYKKVLDIEGDNA--------TEAMKRDYESAKKKVEQSLNLE 226
Cdd:COG0457    88 ALGRYEEALEDYDKALELDPDDAealynlglALLELGRYDEAIEAYERALELD 140
SGTA_dimer pfam16546
Homodimerization domain of SGTA; SGTA_dimer is a short N-terminal domain at the start of SGTA ...
 7-71 2.64e-16

Homodimerization domain of SGTA; SGTA_dimer is a short N-terminal domain at the start of SGTA or small glutamine-rich tetratricopeptide repeat-containing proteins. It is the homodimerization domain of the SGTA, a heat-shock protein (HSP) co-chaperone involved in the targeting of tail-anchor membrane proteins to the endoplasmic reticulum. This N-terminal homodimerization domain mediates the association with a single copy of Get4 or Get5 proteins, providing a link to the rest of the GET pathway.


Pssm-ID: 465168  Cd Length: 64  Bit Score: 72.17  E-value: 2.64e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1980420102   7 EIAALIVNYFSSIVEKKEISEDGADSLNVAMDCISEAFGFEREAVSGIlgKSEFKGQHLADILNS 71
Cdd:pfam16546   2 RLALSIIDFLSTSLSDGTLSEDDAESLEVAIQCIAEAFEVDPDDEAAV--VKAFGGQSLLEIFEV 64
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 93-204 1.03e-15

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 78.11  E-value: 1.03e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102  93 EDDAETKAKAEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRG 172
Cdd:COG3914    69 AAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEA 148

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1980420102 173 YSRLGFAKYAQGKPEEALEAYKKVLDIEGDNA 204
Cdd:COG3914   149 YLNLGEALRRLGRLEEAIAALRRALELDPDNA 180
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
116-205 5.93e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 73.50  E-value: 5.93e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 116 KDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKK 195
Cdd:COG0457    56 GRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYER 135

                          90
                  ....*....|
gi 1980420102 196 VLDIEGDNAT 205
Cdd:COG0457   136 ALELDPDDAD 145
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 102-210 1.44e-14

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 69.65  E-value: 1.44e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 102 AEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKY 181
Cdd:COG4235    17 AEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAF 96

                          90       100
                  ....*....|....*....|....*....
gi 1980420102 182 AQGKPEEALEAYKKVLDIEGDNATEAMKR 210
Cdd:COG4235    97 QQGDYAEAIAAWQKLLALLPADAPARLLE 125
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 100-204 7.05e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 67.91  E-value: 7.05e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 100 AKAEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFA 179
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                          90       100
                  ....*....|....*....|....*
gi 1980420102 180 KYAQGKPEEALEAYKKVLDIEGDNA 204
Cdd:COG4783    82 LLKAGDYDEALALLEKALKLDPEHP 106
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 113-240 3.80e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 68.60  E-value: 3.80e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 113 MANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEA 192
Cdd:COG2956   121 EQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAA 200

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1980420102 193 YKKVLDIEGDNAT--EAMKRDYESAKKKVEQSLNLEKTVPEQSRDADVDA 240
Cdd:COG2956   201 LERALEQDPDYLPalPRLAELYEKLGDPEEALELLRKALELDPSDDLLLA 250
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
129-231 7.08e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 67.34  E-value: 7.08e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 129 IKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDIEGDNA---- 204
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAealn 80

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1980420102 205 ----TEAMKRDYESAKKKVEQSLNLEKTVPE 231
Cdd:COG0457    81 nlglALQALGRYEEALEDYDKALELDPDDAE 111
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 102-240 1.09e-12

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 68.27  E-value: 1.09e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 102 AEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKY 181
Cdd:PLN03088    2 AKDLEDKAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACM 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1980420102 182 AQGKPEEALEAYKKVLDIEGDNA--TEAMKRDYESAKKKVEQSLNLEKTVPEQSRDADVDA 240
Cdd:PLN03088   82 KLEEYQTAKAALEKGASLAPGDSrfTKLIKECDEKIAEEEKDLVQPVPSDLPSSVTAPPVE 142
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 109-225 1.19e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.06  E-value: 1.19e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 109 GNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEE 188
Cdd:COG2956   151 AELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEE 230

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1980420102 189 ALEAYKKVLDIEGDNATEAMKRDYESAKKKVEQSLNL 225
Cdd:COG2956   231 ALELLRKALELDPSDDLLLALADLLERKEGLEAALAL 267
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
102-246 1.35e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 66.57  E-value: 1.35e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 102 AEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKY 181
Cdd:COG0457    76 AEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALE 155

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1980420102 182 AQGKPEEALEAYKKVLDIEGDNATEAMKRDYESAKKKVEQSLNLEKTVPEQSRDADVDASQGASA 246
Cdd:COG0457   156 KLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALA 220
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 102-204 1.46e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 68.48  E-value: 1.46e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 102 AEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKY 181
Cdd:COG3914   112 AEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQ 191

                          90       100
                  ....*....|....*....|...
gi 1980420102 182 AQGKPEEALEAYKKVLDIEGDNA 204
Cdd:COG3914   192 DLGRLEEAIAAYRRALELDPDNA 214
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 77-190 2.52e-12

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 67.70  E-value: 2.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102  77 ESNKKDDAENVeINIPEDdaETKAKAEDLKMQGNKAMANKDYELAINKYTEAIKVLPtNAIYYANRAAAHSSLKEYDQAV 156
Cdd:TIGR00990 105 DELPEIDESSV-ANLSEE--ERKKYAAKLKEKGNKAYRNKDFNKAIKLYSKAIECKP-DPVYYSNRAACHNALGDWEKVV 180

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1980420102 157 KDAESAISIDPSYFRGYSRLGFAKYAQGKPEEAL 190
Cdd:TIGR00990 181 EDTTAALELDPDYSKALNRRANAYDGLGKYADAL 214
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 92-200 1.10e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 62.29  E-value: 1.10e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102  92 PEDDAETKAKAEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFR 171
Cdd:COG5010    44 AAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPN 123

                          90       100
                  ....*....|....*....|....*....
gi 1980420102 172 GYSRLGFAKYAQGKPEEALEAYKKVLDIE 200
Cdd:COG5010   124 AYSNLAALLLSLGQDDEAKAALQRALGTS 152
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 112-203 6.89e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 59.44  E-value: 6.89e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 112 AMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALE 191
Cdd:COG4783    48 LLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIA 127

                          90
                  ....*....|..
gi 1980420102 192 AYKKVLDIEGDN 203
Cdd:COG4783   128 ALEKALELDPDD 139
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
112-202 1.96e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 57.10  E-value: 1.96e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 112 AMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKdAESAISIDPSYFRGYSRLGFAKYAQGKPEEALE 191
Cdd:COG3063     2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80

                          90
                  ....*....|.
gi 1980420102 192 AYKKVLDIEGD 202
Cdd:COG3063    81 YLERALELDPS 91
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 113-226 2.19e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 60.51  E-value: 2.19e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 113 MANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEA 192
Cdd:COG2956    87 LKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEA 166

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1980420102 193 YKKVLDIEGDNA--------TEAMKRDYESAKKKVEQSLNLE 226
Cdd:COG2956   167 LEKALKLDPDCArallllaeLYLEQGDYEEAIAALERALEQD 208
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 121-241 3.22e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 54.63  E-value: 3.22e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 121 AINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDIE 200
Cdd:COG4235     2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 1980420102 201 GDNAT--------EAMKRDYESAKKKVEQSLNLEktvPEQSRDADVDAS 241
Cdd:COG4235    82 PDNPEalyllglaAFQQGDYAEAIAAWQKLLALL---PADAPARLLEAS 127
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 107-225 3.56e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.05  E-value: 3.56e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 107 MQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKP 186
Cdd:COG2956    13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLL 92

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 1980420102 187 EEALEAYKKVLDIEGDNAT--------EAMKRDYESAKKKVEQSLNL 225
Cdd:COG2956    93 DRAEELLEKLLELDPDDAEalrllaeiYEQEGDWEKAIEVLERLLKL 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 102-204 1.36e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.15  E-value: 1.36e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 102 AEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKY 181
Cdd:COG3914    44 ALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLL 123

                          90       100
                  ....*....|....*....|...
gi 1980420102 182 AQGKPEEALEAYKKVLDIEGDNA 204
Cdd:COG3914   124 ALGRLEEALAALRRALALNPDFA 146
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 109-189 1.90e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.77  E-value: 1.90e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 109 GNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEE 188
Cdd:COG3914   153 GEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEV 232


                  .
gi 1980420102 189 A 189
Cdd:COG3914   233 Y 233
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 136-227 2.58e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 49.57  E-value: 2.58e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 136 AIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDIEGDNAT--------EA 207
Cdd:COG5010    54 FAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNaysnlaalLL 133

                          90       100
                  ....*....|....*....|
gi 1980420102 208 MKRDYESAKKKVEQSLNLEK 227
Cdd:COG5010   134 SLGQDDEAKAALQRALGTSP 153
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
145-226 3.38e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 47.86  E-value: 3.38e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 145 AHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALeAYKKVLDIEGDNAT--------EAMKRDYESAK 216
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNNAEallnlaelLLELGDYDEAL 79

                          90
                  ....*....|
gi 1980420102 217 KKVEQSLNLE 226
Cdd:COG3063    80 AYLERALELD 89
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 154-226 2.21e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.54  E-value: 2.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 154 QAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDIEGDNA--------TEAMKRDYESAKKKVEQSLNL 225
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNAdalldlaeALLAAGDTEEAEELLERALAL 80


                  .
gi 1980420102 226 E 226
Cdd:COG4235    81 D 81
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 65-204 2.57e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.31  E-value: 2.57e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102  65 LADILNSASRVPESNKKddAENVEINIPEDdaetkakAEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIyYANRAA 144
Cdd:TIGR02917 675 LAQLLLAAKRTESAKKI--AKSLQKQHPKA-------ALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQN-AIKLHR 744

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 145 AHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDIEGDNA 204
Cdd:TIGR02917 745 ALLASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNA 804
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 102-204 7.49e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.77  E-value: 7.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 102 AEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAiyYANRAAAHSSL--KEYDQAVKDAESAISIDPSYFRGYSRLGFA 179
Cdd:TIGR02917 125 AELLALRGLAYLGLGQLELAQKSYEQALAIDPRSL--YAKLGLAQLALaeNRFDEARALIDEVLTADPGNVDALLLKGDL 202

                          90       100
                  ....*....|....*....|....*
gi 1980420102 180 KYAQGKPEEALEAYKKVLDIEGDNA 204
Cdd:TIGR02917 203 LLSLGNIELALAAYRKAIALRPNNI 227
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 65-197 1.11e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.39  E-value: 1.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102  65 LADILNSASRvPESNKKDDAENVEINIPEDDAetkakaedLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAA 144
Cdd:TIGR02917 165 LAQLALAENR-FDEARALIDEVLTADPGNVDA--------LLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALAT 235

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1980420102 145 AHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVL 197
Cdd:TIGR02917 236 ILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDAL 288
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 99-228 2.36e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.23  E-value: 2.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102  99 KAKAEDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGF 178
Cdd:TIGR02917 598 PDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQ 677

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 179 AKYAQGKPEEALEAYKKV----------LDIEGDNAteAMKRDYESAKKKVEQSLNLEKT 228
Cdd:TIGR02917 678 LLLAAKRTESAKKIAKSLqkqhpkaalgFELEGDLY--LRQKDYPAAIQAYRKALKRAPS 735
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 111-198 4.75e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 42.29  E-value: 4.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 111 KAMANKDYELAINKYTEAIKVLPT-----NAIYYanRAAAHSSLKEYDQAVKDAESAISIDPSYFR---GYSRLGFAKYA 182
Cdd:COG1729     2 ALLKAGDYDEAIAAFKAFLKRYPNsplapDALYW--LGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLE 79

                          90
                  ....*....|....*.
gi 1980420102 183 QGKPEEALEAYKKVLD 198
Cdd:COG1729    80 LGDYDKARATLEELIK 95
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 103-221 5.73e-05

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 44.16  E-value: 5.73e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 103 EDLKMQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYfrgysrlGFAKY- 181
Cdd:cd24142     1 DELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDG-------GYEKYl 73

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1980420102 182 --AQ-GKPEEALEAYKK---VLDIEGDNATEAMKRDYESAKKKVEQ 221
Cdd:cd24142    74 ylGQlSGGEEALQYYEKgieILEEELQALQAASAEAEEEAEELKRK 119
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 65-227 8.19e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 8.19e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102  65 LADILNSASRVPESnkKDDAENVEINIPEDDAETKAKAEDLKMQGNKAMAnkdyelaINKYTEAIKVLPTNAIYYANRAA 144
Cdd:TIGR02917 505 LARIDIQEGNPDDA--IQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEA-------VAWLEKAAELNPQEIEPALALAQ 575

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 145 AHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDIEGDNAT--------EAMKRDYESAK 216
Cdd:TIGR02917 576 YYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALalllladaYAVMKNYAKAI 655

                         170
                  ....*....|.
gi 1980420102 217 KKVEQSLNLEK 227
Cdd:TIGR02917 656 TSLKRALELKP 666
BTAD smart01043
Bacterial transcriptional activator domain; Found in the DNRI/REDD/AFSR family of regulators. ...
 142-208 1.04e-04

Bacterial transcriptional activator domain; Found in the DNRI/REDD/AFSR family of regulators. This region of AFSR along with the C terminal region is capable of independently directing actinorhodin production. This family contains TPR repeats.


Pssm-ID: 198111 [Multi-domain]  Cd Length: 145  Bit Score: 41.90  E-value: 1.04e-04
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1980420102  142 RAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKV-------LDIEGDNATEAM 208
Cdd:smart01043  67 LAEALLALGRHEEALALLERLLALDPLRERLHRLLMRALYRAGRRAEALRAYRRLrrlladeLGVEPGPELRAL 140
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 55-243 1.43e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.53  E-value: 1.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102  55 LGKSEFKGQHLADILnsaSRVPES-------------NKKDDAENVEINIPEDDAETKAKAedLKMQGNKAMANKDYELA 121
Cdd:TIGR02917 308 LGNLEQAYQYLNQIL---KYAPNShqarrllasiqlrLGRVDEAIATLSPALGLDPDDPAA--LSLLGEAYLALGDFEKA 382

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 122 INKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDIEG 201
Cdd:TIGR02917 383 AEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQP 462

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1980420102 202 DNA--------TEAMKRDYESAKKKVEQSLNLEKT-VPEQSRDADVDASQG 243
Cdd:TIGR02917 463 DNAslhnllgaIYLGKGDLAKAREAFEKALSIEPDfFPAAANLARIDIQEG 513
TPR_1 pfam00515
Tetratricopeptide repeat;
136-169 1.93e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.17  E-value: 1.93e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1980420102 136 AIYYANRAAAHSSLKEYDQAVKDAESAISIDPSY 169
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
171-203 2.24e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.17  E-value: 2.24e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1980420102 171 RGYSRLGFAKYAQGKPEEALEAYKKVLDIEGDN 203
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 121-227 2.68e-04

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 42.66  E-value: 2.68e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 121 AINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKK----- 195
Cdd:TIGR00990 384 AEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRckknf 463

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1980420102 196 -----VLDIEGDNATEamKRDYESAKKKVEQSLNLEK 227
Cdd:TIGR00990 464 peapdVYNYYGELLLD--QNKFDEAIEKFDTAIELEK 498
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
109-171 3.63e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 39.00  E-value: 3.63e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1980420102 109 GNKAMANKDYELAInKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFR 171
Cdd:COG3063    33 GLLLLEQGRYDEAI-ALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPSALR 94
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 107-197 5.29e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.25  E-value: 5.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 107 MQGNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYfRGYSRLGFAKYAQGKP 186
Cdd:COG2956   183 LLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGL 261

                          90
                  ....*....|.
gi 1980420102 187 EEALEAYKKVL 197
Cdd:COG2956   262 EAALALLERQL 272
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 113-167 6.49e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.94  E-value: 6.49e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1980420102 113 MANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDP 167
Cdd:COG5010    99 SRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 136-169 7.22e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 7.22e-04
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1980420102  136 AIYYANRAAAHSSLKEYDQAVKDAESAISIDPSY 169
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_11 pfam13414
TPR repeat;
148-184 7.87e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.68  E-value: 7.87e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1980420102 148 SLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQG 184
Cdd:pfam13414   6 EQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 136-217 9.08e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 40.48  E-value: 9.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 136 AIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAYKKVLDIEGDNATEAMK--RDYE 213
Cdd:COG2956     8 ALGWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLElaQDYL 87


                  ....
gi 1980420102 214 SAKK 217
Cdd:COG2956    88 KAGL 91
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 170-203 1.09e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.89  E-value: 1.09e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1980420102  170 FRGYSRLGFAKYAQGKPEEALEAYKKVLDIEGDN 203
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
75-196 1.24e-03

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 39.87  E-value: 1.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102  75 VPESNKKDDAENVEINIPE---DDAETKAKAEDLKMQG---NKAM------ANKDYELAINKYTEAIKVLPTNAIYYANR 142
Cdd:COG4700    50 LPELRNSRDARRVQRAARNaldPGRELRELEKALEFADtvqNRVRladallELGRYDEAIELYEEALTGIFADDPHILLG 129

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1980420102 143 AA-AHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAK--YAQGKPEEALEAYKKV 196
Cdd:COG4700   130 LAqALFELGRYAEALETLEKLIAKNPDFKSSDAHLLYARalEALGDLEAAEAELEAL 186
STI1 smart00727
Heat shock chaperonin-binding motif;
264-298 1.63e-03

Heat shock chaperonin-binding motif;


Pssm-ID: 128966  Cd Length: 41  Bit Score: 35.71  E-value: 1.63e-03
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 1980420102  264 MNNPQLMQAAQKMMSNPgamQNIQKMMQ-DPSIRQM 298
Cdd:smart00727   8 LQNPQVQSLLQDMQQNP---DMLAQMLQeNPQLLQL 40
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 109-169 3.58e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.48  E-value: 3.58e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1980420102 109 GNKAMANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSY 169
Cdd:COG4783    79 GLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 114-232 6.94e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.53  E-value: 6.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1980420102 114 ANKDYELAINKYTEAIKVLPTNAIYYANRAAAHSSLKEYDQAVKDAESAISIDPSYFRGYSRLGFAKYAQGKPEEALEAY 193
Cdd:TIGR02917 579 GKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSL 658

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1980420102 194 KKVLDIEGDNaTEA--MKRDYESAKKKVEQSLNLEKTVPEQ 232
Cdd:TIGR02917 659 KRALELKPDN-TEAqiGLAQLLLAAKRTESAKKIAKSLQKQ 698
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 170-200 9.49e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 33.27  E-value: 9.49e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1980420102 170 FRGYSRLGFAKYAQGKPEEALEAYKKVLDIE 200
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELD 31
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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