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Conserved domains on  [gi|1940526636|gb|KAF9892634|]
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hypothetical protein FE257_001036 [Aspergillus nanangensis]

Protein Classification

GMC family oxidoreductase( domain architecture ID 11455227)

GMC (glucose-methanol-choline) family oxidoreductase is a flavoprotein that catalyzes the oxidation of an alcohol moiety to the corresponding aldehyde with the concomitant reduction of flavin adenine dinucleotide (FAD)

EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0050660
PubMed:  23578136|1542121
SCOP:  3000055

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 55-638 7.80e-139

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


:

Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 415.38  E-value: 7.80e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636  55 DQSFDYVVVGGGTAGNAIGVRLAE-AGFSVAIIEAGlfyEMGKPVLGSTPAGAFFGVGgklldsDPLVDWEFITEPQIGA 133
Cdd:COG2303     2 LEEYDYVIVGAGSAGCVLANRLSEdAGLRVLLLEAG---GRDDDPLIRMPAGYAKLLG------NPRYDWRYETEPQPGL 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 134 KNRQVHYARGKCLGGSSALNFMIHHRGSAGSYEQWAdQVGDDTYRLDNFMPYFQKSVNFSRPNTEIRRenattlydnslf 213
Cdd:COG2303    73 NGRRLYWPRGKVLGGSSSINGMIYVRGQPEDFDLWA-QLGNQGWGYDDVLPYFKRAEDNERGADAYHG------------ 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 214 tqPGGPIQVGYTNWVSTWATWLEQGLKAVGLNVTTGFSSGQLLGYHYSQSTIRssDQTR-STSAEYVHSIKesaARKNLK 292
Cdd:COG2303   140 --RSGPLPVSDPPLPNPLSDAFIEAAEELGIPRADDFNGGACEGCGFCQVTCR--NGARwSAARAYLPPAL---KRPNLT 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 293 VYTQTVAKRVLFDGKRAKGVEVSLLGAlpTYTIKANKEVILSAGVFQSPQLLMLSGIGPRAVLDEFDIPVLSDLEGVGQN 372
Cdd:COG2303   213 VRTGALVTRILFDGGRATGVEYRDDGE--EHTVRAAREVILAAGAINSPQLLLLSGIGPASHLREHGIPVVHDLPGVGRN 290

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 373 MWDHIMFGPSYEVNFPtldKTLHDPVALAGALLEYSTAARGPLSSNVVEFLGWeklpakyrdklsYATRNALssfpdDWP 452
Cdd:COG2303   291 LQDHLEVSVVFRFKEP---VTLNKSLRKARIGLQYLLTRSGPLTSNVAEAGGF------------FRSDPGL-----ERP 350

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 453 ELEHisgngfigdFAFPVLQQPLNGKQ---YATNLGAMVAPL---SRGNVTIRSRDAAILPKINPNWLTHPADQEVAIAW 526
Cdd:COG2303   351 DLQF---------HFLPLGLTPRWGKKalhDGHGFTAHVEQLrpeSRGRVTLDSADPLGAPLIRPNYLSDENDRRVLVAG 421

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 527 YRRMREVWDTPALRSIRvgEEEAYPGLDKATDEQiLEVVRSSLMTVWHAACTCKMGksSDSSAVVDNFARVFGVEGLRVV 606
Cdd:COG2303   422 VRLAREIAAQPALAPYR--GEEILPGPDVQSDEE-LAFIRARAYTIYHPVGTCRMG--TDPDSVVDPRLRVHGVENLRVV 496

                         570       580       590
                  ....*....|....*....|....*....|..
gi 1940526636 607 DSSAFPLLPPGHPQSTVYALAEKIADGIIKGM 638
Cdd:COG2303   497 DASVMPTITSGNTNAPTIMLAEKAADMILGDY 528
 
Name Accession Description Interval E-value
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 55-638 7.80e-139

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 415.38  E-value: 7.80e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636  55 DQSFDYVVVGGGTAGNAIGVRLAE-AGFSVAIIEAGlfyEMGKPVLGSTPAGAFFGVGgklldsDPLVDWEFITEPQIGA 133
Cdd:COG2303     2 LEEYDYVIVGAGSAGCVLANRLSEdAGLRVLLLEAG---GRDDDPLIRMPAGYAKLLG------NPRYDWRYETEPQPGL 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 134 KNRQVHYARGKCLGGSSALNFMIHHRGSAGSYEQWAdQVGDDTYRLDNFMPYFQKSVNFSRPNTEIRRenattlydnslf 213
Cdd:COG2303    73 NGRRLYWPRGKVLGGSSSINGMIYVRGQPEDFDLWA-QLGNQGWGYDDVLPYFKRAEDNERGADAYHG------------ 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 214 tqPGGPIQVGYTNWVSTWATWLEQGLKAVGLNVTTGFSSGQLLGYHYSQSTIRssDQTR-STSAEYVHSIKesaARKNLK 292
Cdd:COG2303   140 --RSGPLPVSDPPLPNPLSDAFIEAAEELGIPRADDFNGGACEGCGFCQVTCR--NGARwSAARAYLPPAL---KRPNLT 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 293 VYTQTVAKRVLFDGKRAKGVEVSLLGAlpTYTIKANKEVILSAGVFQSPQLLMLSGIGPRAVLDEFDIPVLSDLEGVGQN 372
Cdd:COG2303   213 VRTGALVTRILFDGGRATGVEYRDDGE--EHTVRAAREVILAAGAINSPQLLLLSGIGPASHLREHGIPVVHDLPGVGRN 290

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 373 MWDHIMFGPSYEVNFPtldKTLHDPVALAGALLEYSTAARGPLSSNVVEFLGWeklpakyrdklsYATRNALssfpdDWP 452
Cdd:COG2303   291 LQDHLEVSVVFRFKEP---VTLNKSLRKARIGLQYLLTRSGPLTSNVAEAGGF------------FRSDPGL-----ERP 350

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 453 ELEHisgngfigdFAFPVLQQPLNGKQ---YATNLGAMVAPL---SRGNVTIRSRDAAILPKINPNWLTHPADQEVAIAW 526
Cdd:COG2303   351 DLQF---------HFLPLGLTPRWGKKalhDGHGFTAHVEQLrpeSRGRVTLDSADPLGAPLIRPNYLSDENDRRVLVAG 421

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 527 YRRMREVWDTPALRSIRvgEEEAYPGLDKATDEQiLEVVRSSLMTVWHAACTCKMGksSDSSAVVDNFARVFGVEGLRVV 606
Cdd:COG2303   422 VRLAREIAAQPALAPYR--GEEILPGPDVQSDEE-LAFIRARAYTIYHPVGTCRMG--TDPDSVVDPRLRVHGVENLRVV 496

                         570       580       590
                  ....*....|....*....|....*....|..
gi 1940526636 607 DSSAFPLLPPGHPQSTVYALAEKIADGIIKGM 638
Cdd:COG2303   497 DASVMPTITSGNTNAPTIMLAEKAADMILGDY 528
PRK02106 PRK02106
choline dehydrogenase; Validated
 55-637 7.84e-112

choline dehydrogenase; Validated


Pssm-ID: 235000 [Multi-domain]  Cd Length: 560  Bit Score: 346.82  E-value: 7.84e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636  55 DQSFDYVVVGGGTAGNAIGVRLAE-AGFSVAIIEAG-------LFYEMgkpvlgstPAGAFFGVGGKLLDsdplvdWEFI 126
Cdd:PRK02106    3 TMEYDYIIIGAGSAGCVLANRLSEdPDVSVLLLEAGgpdyrwdFFIQM--------PAALAFPLQGKRYN------WAYE 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 127 TEPQIGAKNRQVHYARGKCLGGSSALNFMIHHRGSAGSYEQWADQVGDDTYRLDNFMPYFQKSVNFSRPNTEIRRENatt 206
Cdd:PRK02106   69 TEPEPHMNNRRMECPRGKVLGGSSSINGMVYIRGNAMDYDNWAELPGLEGWSYADCLPYFKKAETRDGGEDDYRGGD--- 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 207 lydnslftqpgGPIqvgytnWVST--------WATWLEQGLKAvGLNVTTGFSSGQLLGYHYSQSTIRssDQTR-STSAE 277
Cdd:PRK02106  146 -----------GPL------SVTRgkpgtnplFQAFVEAGVQA-GYPRTDDLNGYQQEGFGPMDRTVT--NGRRwSAARA 205

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 278 YVHSIKEsaaRKNLKVYTQTVAKRVLFDGKRAKGVEVSLLGAlpTYTIKANKEVILSAGVFQSPQLLMLSGIGPRAVLDE 357
Cdd:PRK02106  206 YLDPALK---RPNLTIVTHALTDRILFEGKRAVGVEYERGGG--RETARARREVILSAGAINSPQLLQLSGIGPAEHLKE 280

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 358 FDIPVLSDLEGVGQNMWDHIMFGPSYEVNfptldktlhDPVALAGAL---------LEYSTAARGPLSSNVVE---FLgw 425
Cdd:PRK02106  281 LGIPVVHDLPGVGENLQDHLEVYIQYECK---------QPVSLYPALkwwnkpkigAEWLFTGTGLGASNHFEaggFI-- 349

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 426 eklpaKYRDKLsyatrnalssfpdDWPELE-H-----ISGNGfigdfafpvlQQPLNGKQYATNLGAMVAPlSRGNVTIR 499
Cdd:PRK02106  350 -----RSRAGV-------------DWPNIQyHflpvaIRYDG----------SNAVKGHGFQAHVGPMRSP-SRGSVKLK 400

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 500 SRDAAILPKINPNWLTHPADQEVAIAWYRRMREVWDTPALRSIRvGEEEAyPGLDKATDEQILEVVRSSLMTVWHAACTC 579
Cdd:PRK02106  401 SADPRAHPSILFNYMSTEQDWREFRDAIRLTREIMAQPALDPYR-GREIS-PGADVQTDEEIDAFVREHAETAYHPSCTC 478

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1940526636 580 KMGksSDSSAVVDNFARVFGVEGLRVVDSSAFPLLPPGHPQSTVYALAEKIADgIIKG 637
Cdd:PRK02106  479 KMG--TDPMAVVDPEGRVHGVEGLRVVDASIMPTITNGNLNAPTIMIAEKAAD-LIRG 533
GMC_oxred_C pfam05199
GMC oxidoreductase; This domain found associated with pfam00732.
 490-630 3.53e-46

GMC oxidoreductase; This domain found associated with pfam00732.


Pssm-ID: 398739 [Multi-domain]  Cd Length: 143  Bit Score: 159.87  E-value: 3.53e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 490 PLSRGNVTIRSRDAAILPKINPNWLTHPADQEVAIAWYRRMREVWDTPALR---SIRVGEEEAYPGLDKATDEQILEVVR 566
Cdd:pfam05199   1 PRSRGRVTLSSSDPTGLPVIDPNYLSDPADLAALRAALRLARRILAAAGLVlgvELTPGPVPEVSDAAVTSDDELLAYIR 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1940526636 567 SSLMTVWHAACTCKMGKSSDSSaVVDNFARVFGVEGLRVVDSSAFPLLPPGHPQSTVYALAEKI 630
Cdd:pfam05199  81 AAASTSYHPMGTCRMGADPDDA-VVDPDLRVHGVDNLRVVDASVFPSSPSGNPTLTIYALAERA 143
glycerol3P_GlpB TIGR03378
glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; Members of this protein family are ...
 58-105 1.87e-04

glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; Members of this protein family are the B subunit, product of the glpB gene, of a three-subunit, membrane-anchored, FAD-dependent anaerobic glycerol-3-phosphate dehydrogenase. [Energy metabolism, Anaerobic]


Pssm-ID: 213807  Cd Length: 419  Bit Score: 44.24  E-value: 1.87e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1940526636  58 FDYVVVGGGTAGNAIGVRLAEAGFSVAIIEAG---LFYEMGK-PVLGSTPAG 105
Cdd:TIGR03378   1 FDVIIIGGGLAGLSCALRLAEAGKKCAIIAAGqsaLHFSSGSlDLLSRLPDG 52
 
Name Accession Description Interval E-value
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 55-638 7.80e-139

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 415.38  E-value: 7.80e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636  55 DQSFDYVVVGGGTAGNAIGVRLAE-AGFSVAIIEAGlfyEMGKPVLGSTPAGAFFGVGgklldsDPLVDWEFITEPQIGA 133
Cdd:COG2303     2 LEEYDYVIVGAGSAGCVLANRLSEdAGLRVLLLEAG---GRDDDPLIRMPAGYAKLLG------NPRYDWRYETEPQPGL 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 134 KNRQVHYARGKCLGGSSALNFMIHHRGSAGSYEQWAdQVGDDTYRLDNFMPYFQKSVNFSRPNTEIRRenattlydnslf 213
Cdd:COG2303    73 NGRRLYWPRGKVLGGSSSINGMIYVRGQPEDFDLWA-QLGNQGWGYDDVLPYFKRAEDNERGADAYHG------------ 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 214 tqPGGPIQVGYTNWVSTWATWLEQGLKAVGLNVTTGFSSGQLLGYHYSQSTIRssDQTR-STSAEYVHSIKesaARKNLK 292
Cdd:COG2303   140 --RSGPLPVSDPPLPNPLSDAFIEAAEELGIPRADDFNGGACEGCGFCQVTCR--NGARwSAARAYLPPAL---KRPNLT 212

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 293 VYTQTVAKRVLFDGKRAKGVEVSLLGAlpTYTIKANKEVILSAGVFQSPQLLMLSGIGPRAVLDEFDIPVLSDLEGVGQN 372
Cdd:COG2303   213 VRTGALVTRILFDGGRATGVEYRDDGE--EHTVRAAREVILAAGAINSPQLLLLSGIGPASHLREHGIPVVHDLPGVGRN 290

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 373 MWDHIMFGPSYEVNFPtldKTLHDPVALAGALLEYSTAARGPLSSNVVEFLGWeklpakyrdklsYATRNALssfpdDWP 452
Cdd:COG2303   291 LQDHLEVSVVFRFKEP---VTLNKSLRKARIGLQYLLTRSGPLTSNVAEAGGF------------FRSDPGL-----ERP 350

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 453 ELEHisgngfigdFAFPVLQQPLNGKQ---YATNLGAMVAPL---SRGNVTIRSRDAAILPKINPNWLTHPADQEVAIAW 526
Cdd:COG2303   351 DLQF---------HFLPLGLTPRWGKKalhDGHGFTAHVEQLrpeSRGRVTLDSADPLGAPLIRPNYLSDENDRRVLVAG 421

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 527 YRRMREVWDTPALRSIRvgEEEAYPGLDKATDEQiLEVVRSSLMTVWHAACTCKMGksSDSSAVVDNFARVFGVEGLRVV 606
Cdd:COG2303   422 VRLAREIAAQPALAPYR--GEEILPGPDVQSDEE-LAFIRARAYTIYHPVGTCRMG--TDPDSVVDPRLRVHGVENLRVV 496

                         570       580       590
                  ....*....|....*....|....*....|..
gi 1940526636 607 DSSAFPLLPPGHPQSTVYALAEKIADGIIKGM 638
Cdd:COG2303   497 DASVMPTITSGNTNAPTIMLAEKAADMILGDY 528
PRK02106 PRK02106
choline dehydrogenase; Validated
 55-637 7.84e-112

choline dehydrogenase; Validated


Pssm-ID: 235000 [Multi-domain]  Cd Length: 560  Bit Score: 346.82  E-value: 7.84e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636  55 DQSFDYVVVGGGTAGNAIGVRLAE-AGFSVAIIEAG-------LFYEMgkpvlgstPAGAFFGVGGKLLDsdplvdWEFI 126
Cdd:PRK02106    3 TMEYDYIIIGAGSAGCVLANRLSEdPDVSVLLLEAGgpdyrwdFFIQM--------PAALAFPLQGKRYN------WAYE 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 127 TEPQIGAKNRQVHYARGKCLGGSSALNFMIHHRGSAGSYEQWADQVGDDTYRLDNFMPYFQKSVNFSRPNTEIRRENatt 206
Cdd:PRK02106   69 TEPEPHMNNRRMECPRGKVLGGSSSINGMVYIRGNAMDYDNWAELPGLEGWSYADCLPYFKKAETRDGGEDDYRGGD--- 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 207 lydnslftqpgGPIqvgytnWVST--------WATWLEQGLKAvGLNVTTGFSSGQLLGYHYSQSTIRssDQTR-STSAE 277
Cdd:PRK02106  146 -----------GPL------SVTRgkpgtnplFQAFVEAGVQA-GYPRTDDLNGYQQEGFGPMDRTVT--NGRRwSAARA 205

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 278 YVHSIKEsaaRKNLKVYTQTVAKRVLFDGKRAKGVEVSLLGAlpTYTIKANKEVILSAGVFQSPQLLMLSGIGPRAVLDE 357
Cdd:PRK02106  206 YLDPALK---RPNLTIVTHALTDRILFEGKRAVGVEYERGGG--RETARARREVILSAGAINSPQLLQLSGIGPAEHLKE 280

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 358 FDIPVLSDLEGVGQNMWDHIMFGPSYEVNfptldktlhDPVALAGAL---------LEYSTAARGPLSSNVVE---FLgw 425
Cdd:PRK02106  281 LGIPVVHDLPGVGENLQDHLEVYIQYECK---------QPVSLYPALkwwnkpkigAEWLFTGTGLGASNHFEaggFI-- 349

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 426 eklpaKYRDKLsyatrnalssfpdDWPELE-H-----ISGNGfigdfafpvlQQPLNGKQYATNLGAMVAPlSRGNVTIR 499
Cdd:PRK02106  350 -----RSRAGV-------------DWPNIQyHflpvaIRYDG----------SNAVKGHGFQAHVGPMRSP-SRGSVKLK 400

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 500 SRDAAILPKINPNWLTHPADQEVAIAWYRRMREVWDTPALRSIRvGEEEAyPGLDKATDEQILEVVRSSLMTVWHAACTC 579
Cdd:PRK02106  401 SADPRAHPSILFNYMSTEQDWREFRDAIRLTREIMAQPALDPYR-GREIS-PGADVQTDEEIDAFVREHAETAYHPSCTC 478

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1940526636 580 KMGksSDSSAVVDNFARVFGVEGLRVVDSSAFPLLPPGHPQSTVYALAEKIADgIIKG 637
Cdd:PRK02106  479 KMG--TDPMAVVDPEGRVHGVEGLRVVDASIMPTITNGNLNAPTIMIAEKAAD-LIRG 533
GMC_oxred_C pfam05199
GMC oxidoreductase; This domain found associated with pfam00732.
 490-630 3.53e-46

GMC oxidoreductase; This domain found associated with pfam00732.


Pssm-ID: 398739 [Multi-domain]  Cd Length: 143  Bit Score: 159.87  E-value: 3.53e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 490 PLSRGNVTIRSRDAAILPKINPNWLTHPADQEVAIAWYRRMREVWDTPALR---SIRVGEEEAYPGLDKATDEQILEVVR 566
Cdd:pfam05199   1 PRSRGRVTLSSSDPTGLPVIDPNYLSDPADLAALRAALRLARRILAAAGLVlgvELTPGPVPEVSDAAVTSDDELLAYIR 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1940526636 567 SSLMTVWHAACTCKMGKSSDSSaVVDNFARVFGVEGLRVVDSSAFPLLPPGHPQSTVYALAEKI 630
Cdd:pfam05199  81 AAASTSYHPMGTCRMGADPDDA-VVDPDLRVHGVDNLRVVDASVFPSSPSGNPTLTIYALAERA 143
PLN02785 PLN02785
Protein HOTHEAD
 53-623 1.61e-30

Protein HOTHEAD


Pssm-ID: 215420 [Multi-domain]  Cd Length: 587  Bit Score: 126.46  E-value: 1.61e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636  53 GVDQSFDYVVVGGGTAGNAIGVRLAEAgFSVAIIEAGlfyemGKPvLGSTPAGAF--FGVGgkLLDSDPlvdwefiTEP- 129
Cdd:PLN02785   51 GGDSAYDYIVVGGGTAGCPLAATLSQN-FSVLLLERG-----GVP-FGNANVSFLenFHIG--LADTSP-------TSAs 114

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 130 QIGAKNRQVHYARGKCLGGSSALNFMIHHRGSAgsyeQWADQVGDDtyrldnfmpyfQKSVNFSRPNTEIRrenattlyd 209
Cdd:PLN02785  115 QAFISTDGVINARARVLGGGTCINAGFYSRAST----RFIQKAGWD-----------AKLVNESYPWVERQ--------- 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 210 nsLFTQPGgpiqvgytnwVSTWATWLEQGLKAVGLNVTTGFSSGQLLGYHYSqSTIRSSDQTRSTSAEYVhsikESAARK 289
Cdd:PLN02785  171 --IVHWPK----------VAPWQAALRDSLLEVGVSPFNGFTYDHVYGTKVG-GTIFDEFGRRHTAAELL----AAGNPN 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 290 NLKVYTQTVAKRVLFD--GKRAKGVEVSLL---GALPTYTIKANK--EVILSAGVFQSPQLLMLSGIGPRAVLDEFDIPV 362
Cdd:PLN02785  234 KLRVLLHATVQKIVFDtsGKRPRATGVIFKdenGNQHQAFLSNNKgsEIILSAGAIGSPQMLLLSGIGPKKELKKHKIPV 313

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 363 LSDLEGVGQNMWDHIM---FGPSYEVNFPTLDKTLHdpVALAGALLEYSTA----------ARGPLSSNVVEFlgwEKLP 429
Cdd:PLN02785  314 VLHNEHVGKGMADNPMnsiFVPSKAPVEQSLIQTVG--ITKMGVYIEASSGfgqspdsihcHHGIMSAEIGQL---STIP 388

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 430 AKYR--DKL-SYATRNAlssfpdDWPElEHISGnGFIgdfafpvlqqplngkqyatnLGAMVAPLSRGNVTIRSRDAAIL 506
Cdd:PLN02785  389 PKQRtpEAIqAYIHRKK------NLPH-EAFNG-GFI--------------------LEKIAGPISTGHLSLINTNVDDN 440

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 507 PKINPNWLTHPADQEVAIAWYRRMREVwdtpaLRSIRVGEeeaYPGLDKATDEQIL----------------------EV 564
Cdd:PLN02785  441 PSVTFNYFKHPQDLQRCVYGIRTIEKI-----VKTNHFTN---FTQCDKQTMEKVLnmsvkaninlipkhtndtksleQF 512

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1940526636 565 VRSSLMTVWHAACTCKMGKssdssaVVDNFARVFGVEGLRVVDSSAFPLLPPGHPQSTV 623
Cdd:PLN02785  513 CKDTVITIWHYHGGCHVGK------VVDQNYKVLGVSRLRVIDGSTFDESPGTNPQATV 565
GMC_oxred_N pfam00732
GMC oxidoreductase; This family of proteins bind FAD as a cofactor.
 132-376 3.58e-25

GMC oxidoreductase; This family of proteins bind FAD as a cofactor.


Pssm-ID: 366272 [Multi-domain]  Cd Length: 218  Bit Score: 103.90  E-value: 3.58e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 132 GAKNRQVHY-ARGKCLGGSSALNFMIHHRGSAGSYEQWADQVGDDTYRLDNFMPYFQKSVNFSRPNTEIRRENATtlydN 210
Cdd:pfam00732  12 GSVNGRRMIlPAGSTVGGGSSVNWSACIRTPAAVLDEWASEFGLEGWGYDDYLPYMDKVEGPLGVTTKGIEESPL----N 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 211 SLFTQPGgpiqvgytnwvstwatwLEQGLKAVglNVTTGFSSGQLLGY-HYSQST-IRSSdqtrsTSAEYVHSikesAAR 288
Cdd:pfam00732  88 QALLKAA-----------------EELGYPVE--AVPRNSNGCHYCGFcGLGCPTgAKQS-----TARTWLRP----ALE 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1940526636 289 KNLKVYTQTVAKRVLFDG--KRAKGVEVSLLGALPTYTIKANKEVILSAGVFQSPQLLMLSGIGPRAvldefdipvlsdl 366
Cdd:pfam00732 140 RNLRILTGAKAEKIIILGrgGRAVGVEARDGGGGIKRLITAAKEVVVAAGALNTPPLLLRSGLGKNP------------- 206

                         250
                  ....*....|
gi 1940526636 367 EGVGQNMWDH 376
Cdd:pfam00732 207 HPVGKNLQLH 216
PRK06370 PRK06370
FAD-containing oxidoreductase;
56-91 3.88e-06

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 49.82  E-value: 3.88e-06
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1940526636  56 QSFDYVVVGGGTAGNAIGVRLAEAGFSVAIIEAGLF 91
Cdd:PRK06370    4 QRYDAIVIGAGQAGPPLAARAAGLGMKVALIERGLL 39
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 55-91 2.34e-05

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 47.39  E-value: 2.34e-05
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1940526636  55 DQSFDYVVVGGGTAGNAIGVRLAEAGFSVAIIEAGLF 91
Cdd:COG1249     1 MKDYDLVVIGAGPGGYVAAIRAAQLGLKVALVEKGRL 37
glycerol3P_GlpB TIGR03378
glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; Members of this protein family are ...
 58-105 1.87e-04

glycerol-3-phosphate dehydrogenase, anaerobic, B subunit; Members of this protein family are the B subunit, product of the glpB gene, of a three-subunit, membrane-anchored, FAD-dependent anaerobic glycerol-3-phosphate dehydrogenase. [Energy metabolism, Anaerobic]


Pssm-ID: 213807  Cd Length: 419  Bit Score: 44.24  E-value: 1.87e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1940526636  58 FDYVVVGGGTAGNAIGVRLAEAGFSVAIIEAG---LFYEMGK-PVLGSTPAG 105
Cdd:TIGR03378   1 FDVIIIGGGLAGLSCALRLAEAGKKCAIIAAGqsaLHFSSGSlDLLSRLPDG 52
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 55-95 1.91e-04

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 44.37  E-value: 1.91e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 1940526636  55 DQSFDYVVVGGGTAGNAIGVRLAEAGFSVAIIEAGlfyEMG 95
Cdd:PRK06416    2 AFEYDVIVIGAGPGGYVAAIRAAQLGLKVAIVEKE---KLG 39
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
 54-87 2.41e-04

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 43.82  E-value: 2.41e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1940526636  54 VDQSFDYVVVGGGTAGNAIGVRLAEAGFSVAIIE 87
Cdd:PRK08020    2 TNQPTDIAIVGGGMVGAALALGLAQHGFSVAVLE 35
PRK06327 PRK06327
dihydrolipoamide dehydrogenase; Validated
 56-102 2.78e-04

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235779 [Multi-domain]  Cd Length: 475  Bit Score: 43.76  E-value: 2.78e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1940526636  56 QSFDYVVVGGGTAGNAIGVRLAEAGFSVAIIEAgLFYEMGKPVLGST 102
Cdd:PRK06327    3 KQFDVVVIGAGPGGYVAAIRAAQLGLKVACIEA-WKNPKGKPALGGT 48
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 59-95 4.93e-04

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 42.77  E-value: 4.93e-04
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1940526636  59 DYVVVGGGTAGNAIGVRLAEAGFSVAIIEAGLFYEMG 95
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDPGSG 37
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 58-91 5.71e-04

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 42.31  E-value: 5.71e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1940526636  58 FDYVVVGGGTAGNAIGVRLAEAGFSVAIIEAGLF 91
Cdd:TIGR02032   1 YDVVVVGAGPAGASAAYRLADKGLRVLLLEKKSF 34
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
56-89 6.59e-04

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 42.58  E-value: 6.59e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1940526636  56 QSFDYVVVGGGTAGNAIGVRLAEAGFSVAIIEAG 89
Cdd:COG0665     1 ATADVVVIGGGIAGLSTAYHLARRGLDVTVLERG 34
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 54-89 1.56e-03

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 41.39  E-value: 1.56e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1940526636  54 VDQSFDYVVVGGGTAGNAIGVRLAEAGFSVAIIEAG 89
Cdd:COG2072     3 ATEHVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKA 38
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 56-89 1.59e-03

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 41.32  E-value: 1.59e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1940526636  56 QSFDYVVVGGGTAGNAIGVRLAEAGFSVAIIEAG 89
Cdd:PRK06292    2 EKYDVIVIGAGPAGYVAARRAAKLGKKVALIEKG 35
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 59-111 2.25e-03

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 40.73  E-value: 2.25e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1940526636  59 DYVVVGGGTAGNAIGVRLAEAGFSVAIIEAGlfyemgkPVLGSTPA---GAFFGVG 111
Cdd:pfam00890   1 DVLVIGGGLAGLAAALAAAEAGLKVAVVEKG-------QPFGGATAwssGGIDALG 49
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
 57-89 2.36e-03

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 40.52  E-value: 2.36e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1940526636  57 SFDYVVVGGGTAGNAIGVRLAEAGFSVAIIEAG 89
Cdd:PRK08849    3 KYDIAVVGGGMVGAATALGFAKQGRSVAVIEGG 35
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 58-89 2.74e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 40.38  E-value: 2.74e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1940526636  58 FDYVVVGGGTAGNAIGVRLAEAGFSVAIIEAG 89
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIEDE 32
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 59-89 3.16e-03

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 40.22  E-value: 3.16e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1940526636  59 DYVVVGGGTAGNAIGVRLAEAGFSVAIIEAG 89
Cdd:COG3349     5 RVVVVGGGLAGLAAAVELAEAGFRVTLLEAR 35
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
56-90 3.64e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 39.94  E-value: 3.64e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1940526636  56 QSFDYVVVGGGTAGNAIGVRLAEAGFSVAIIEAGL 90
Cdd:PRK07608    4 MKFDVVVVGGGLVGASLALALAQSGLRVALLAPRA 38
PRK05329 PRK05329
glycerol-3-phosphate dehydrogenase subunit GlpB;
58-89 3.90e-03

glycerol-3-phosphate dehydrogenase subunit GlpB;


Pssm-ID: 235412  Cd Length: 422  Bit Score: 40.22  E-value: 3.90e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1940526636  58 FDYVVVGGGTAGNAIGVRLAEAGFSVAIIEAG 89
Cdd:PRK05329    3 FDVLVIGGGLAGLTAALAAAEAGKRVALVAKG 34
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
62-89 9.16e-03

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 35.20  E-value: 9.16e-03
                          10        20
                  ....*....|....*....|....*...
gi 1940526636  62 VVGGGTAGNAIGVRLAEAGFSVAIIEAG 89
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKR 28
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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