hypothetical protein F2P56_004475 [Juglans regia]
Protein Classification
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||||
| BAH super family | cl02608 | BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). ... |
500-616 | 1.16e-45 | ||||||
BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in mammalian DNA methyltransferases and the MTA1 subunits of histone deacetylase complexes. A BAH domain is also found in Yeast Sir3p and in the origin receptor complex protein 1 (Orc1p), where it was found to interact with the N-terminal lobe of the silence information regulator 1 protein (Sir1p), confirming the initial hypothesis that BAH plays a role in protein-protein interactions. The actual alignment was detected with superfamily member cd04716: Pssm-ID: 470629 Cd Length: 122 Bit Score: 160.30 E-value: 1.16e-45
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| CD_CMT3_like | cd18635 | chromodomain of chromomethylase 3, and similar proteins; CHRomatin Organization Modifier ... |
760-816 | 2.26e-33 | ||||||
chromodomain of chromomethylase 3, and similar proteins; CHRomatin Organization Modifier (chromo) domain of DNA (cytosine-5)-methyltransferase chromomethylase 3 (CMT3, EC:2.1.1.37), and similar proteins. CMT3 is primarily a CHG (where H is either A, T or C) methyltransferase and is predominantly expressed in actively replicating cells. The protein is involved in preferentially methylating transposon-related sequences, reducing their mobility. Studies suggest that in order to target DNA methylation, CMT3 associates with H3K9me2-containing nucleosomes through binding of its BAH- and chromo-domains to H3K9me2. A chromodomain is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and which appears to play a role in the functional organization of the eukaryotic nucleus. The chromodomain is implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. : Pssm-ID: 349285 Cd Length: 57 Bit Score: 122.42 E-value: 2.26e-33
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| Dcm super family | cl43082 | DNA-cytosine methylase [Replication, recombination and repair]; |
657-988 | 5.42e-28 | ||||||
DNA-cytosine methylase [Replication, recombination and repair]; The actual alignment was detected with superfamily member COG0270: Pssm-ID: 440040 [Multi-domain] Cd Length: 277 Bit Score: 114.91 E-value: 5.42e-28
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| Name | Accession | Description | Interval | E-value | ||||||
| BAH_plantDCM_I | cd04716 | BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5) ... |
500-616 | 1.16e-45 | ||||||
BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases (DCM) from plants. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects on the genome. These effects include transcriptional repression via inhibition of transcription factor binding, the recruitment of methyl-binding proteins and their associated chromatin remodeling factors, X chromosome inactivation, imprinting, and the suppression of parasitic DNA sequences. DNA methylation is also essential for proper embryonic development and is an important player in both DNA repair and genome stability. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions. Pssm-ID: 240067 Cd Length: 122 Bit Score: 160.30 E-value: 1.16e-45
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| CD_CMT3_like | cd18635 | chromodomain of chromomethylase 3, and similar proteins; CHRomatin Organization Modifier ... |
760-816 | 2.26e-33 | ||||||
chromodomain of chromomethylase 3, and similar proteins; CHRomatin Organization Modifier (chromo) domain of DNA (cytosine-5)-methyltransferase chromomethylase 3 (CMT3, EC:2.1.1.37), and similar proteins. CMT3 is primarily a CHG (where H is either A, T or C) methyltransferase and is predominantly expressed in actively replicating cells. The protein is involved in preferentially methylating transposon-related sequences, reducing their mobility. Studies suggest that in order to target DNA methylation, CMT3 associates with H3K9me2-containing nucleosomes through binding of its BAH- and chromo-domains to H3K9me2. A chromodomain is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and which appears to play a role in the functional organization of the eukaryotic nucleus. The chromodomain is implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Pssm-ID: 349285 Cd Length: 57 Bit Score: 122.42 E-value: 2.26e-33
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| Dcm | COG0270 | DNA-cytosine methylase [Replication, recombination and repair]; |
657-988 | 5.42e-28 | ||||||
DNA-cytosine methylase [Replication, recombination and repair]; Pssm-ID: 440040 [Multi-domain] Cd Length: 277 Bit Score: 114.91 E-value: 5.42e-28
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| BAH | smart00439 | Bromo adjacent homology domain; |
502-616 | 2.52e-22 | ||||||
Bromo adjacent homology domain; Pssm-ID: 214664 [Multi-domain] Cd Length: 121 Bit Score: 93.51 E-value: 2.52e-22
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| BAH | pfam01426 | BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been ... |
502-616 | 1.72e-13 | ||||||
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been called ELM1 and BAM (Bromo adjacent motif) domain. The function of this domain is unknown but may be involved in protein-protein interaction. Pssm-ID: 460207 Cd Length: 120 Bit Score: 68.10 E-value: 1.72e-13
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| Cyt_C5_DNA_methylase | cd00315 | Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many ... |
826-1012 | 1.29e-12 | ||||||
Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects on the mammalian genome. These effects include transcriptional repression via inhibition of transcription factor binding or the recruitment of methyl-binding proteins and their associated chromatin remodeling factors, X chromosome inactivation, imprinting and the suppression of parasitic DNA sequences. DNA methylation is also essential for proper embryonic development and is an important player in both DNA repair and genome stability. Pssm-ID: 238192 [Multi-domain] Cd Length: 275 Bit Score: 69.57 E-value: 1.29e-12
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| Chromo | pfam00385 | Chromo (CHRromatin organization MOdifier) domain; |
761-816 | 2.86e-12 | ||||||
Chromo (CHRromatin organization MOdifier) domain; Pssm-ID: 459793 [Multi-domain] Cd Length: 52 Bit Score: 62.21 E-value: 2.86e-12
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| CHROMO | smart00298 | Chromatin organization modifier domain; |
760-816 | 1.28e-11 | ||||||
Chromatin organization modifier domain; Pssm-ID: 214605 [Multi-domain] Cd Length: 55 Bit Score: 60.69 E-value: 1.28e-11
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| dcm | TIGR00675 | DNA-methyltransferase (dcm); All proteins in this family for which functions are known are ... |
829-948 | 5.58e-11 | ||||||
DNA-methyltransferase (dcm); All proteins in this family for which functions are known are DNA-cytosine methyltransferases. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair] Pssm-ID: 273211 [Multi-domain] Cd Length: 315 Bit Score: 65.04 E-value: 5.58e-11
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| DNA_methylase | pfam00145 | C-5 cytosine-specific DNA methylase; |
829-1018 | 2.09e-10 | ||||||
C-5 cytosine-specific DNA methylase; Pssm-ID: 395093 [Multi-domain] Cd Length: 324 Bit Score: 63.49 E-value: 2.09e-10
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| Name | Accession | Description | Interval | E-value | ||||||
| BAH_plantDCM_I | cd04716 | BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5) ... |
500-616 | 1.16e-45 | ||||||
BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases (DCM) from plants. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects on the genome. These effects include transcriptional repression via inhibition of transcription factor binding, the recruitment of methyl-binding proteins and their associated chromatin remodeling factors, X chromosome inactivation, imprinting, and the suppression of parasitic DNA sequences. DNA methylation is also essential for proper embryonic development and is an important player in both DNA repair and genome stability. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions. Pssm-ID: 240067 Cd Length: 122 Bit Score: 160.30 E-value: 1.16e-45
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| CD_CMT3_like | cd18635 | chromodomain of chromomethylase 3, and similar proteins; CHRomatin Organization Modifier ... |
760-816 | 2.26e-33 | ||||||
chromodomain of chromomethylase 3, and similar proteins; CHRomatin Organization Modifier (chromo) domain of DNA (cytosine-5)-methyltransferase chromomethylase 3 (CMT3, EC:2.1.1.37), and similar proteins. CMT3 is primarily a CHG (where H is either A, T or C) methyltransferase and is predominantly expressed in actively replicating cells. The protein is involved in preferentially methylating transposon-related sequences, reducing their mobility. Studies suggest that in order to target DNA methylation, CMT3 associates with H3K9me2-containing nucleosomes through binding of its BAH- and chromo-domains to H3K9me2. A chromodomain is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and which appears to play a role in the functional organization of the eukaryotic nucleus. The chromodomain is implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Pssm-ID: 349285 Cd Length: 57 Bit Score: 122.42 E-value: 2.26e-33
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| Dcm | COG0270 | DNA-cytosine methylase [Replication, recombination and repair]; |
657-988 | 5.42e-28 | ||||||
DNA-cytosine methylase [Replication, recombination and repair]; Pssm-ID: 440040 [Multi-domain] Cd Length: 277 Bit Score: 114.91 E-value: 5.42e-28
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| BAH | smart00439 | Bromo adjacent homology domain; |
502-616 | 2.52e-22 | ||||||
Bromo adjacent homology domain; Pssm-ID: 214664 [Multi-domain] Cd Length: 121 Bit Score: 93.51 E-value: 2.52e-22
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| BAH | cd04370 | BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). ... |
502-616 | 9.02e-21 | ||||||
BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in mammalian DNA methyltransferases and the MTA1 subunits of histone deacetylase complexes. A BAH domain is also found in Yeast Sir3p and in the origin receptor complex protein 1 (Orc1p), where it was found to interact with the N-terminal lobe of the silence information regulator 1 protein (Sir1p), confirming the initial hypothesis that BAH plays a role in protein-protein interactions. Pssm-ID: 239835 [Multi-domain] Cd Length: 123 Bit Score: 88.99 E-value: 9.02e-21
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| BAH | pfam01426 | BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been ... |
502-616 | 1.72e-13 | ||||||
BAH domain; This domain has been called BAH (Bromo adjacent homology) domain and has also been called ELM1 and BAM (Bromo adjacent motif) domain. The function of this domain is unknown but may be involved in protein-protein interaction. Pssm-ID: 460207 Cd Length: 120 Bit Score: 68.10 E-value: 1.72e-13
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| Cyt_C5_DNA_methylase | cd00315 | Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many ... |
826-1012 | 1.29e-12 | ||||||
Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects on the mammalian genome. These effects include transcriptional repression via inhibition of transcription factor binding or the recruitment of methyl-binding proteins and their associated chromatin remodeling factors, X chromosome inactivation, imprinting and the suppression of parasitic DNA sequences. DNA methylation is also essential for proper embryonic development and is an important player in both DNA repair and genome stability. Pssm-ID: 238192 [Multi-domain] Cd Length: 275 Bit Score: 69.57 E-value: 1.29e-12
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| Chromo | pfam00385 | Chromo (CHRromatin organization MOdifier) domain; |
761-816 | 2.86e-12 | ||||||
Chromo (CHRromatin organization MOdifier) domain; Pssm-ID: 459793 [Multi-domain] Cd Length: 52 Bit Score: 62.21 E-value: 2.86e-12
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| CD_CSD | cd00024 | CHROMO (CHRromatin Organization Modifier) domains and chromo shadow domains; Members of this ... |
761-814 | 1.12e-11 | ||||||
CHROMO (CHRromatin Organization Modifier) domains and chromo shadow domains; Members of this group are chromodomains or chromo shadow domains; these are SH3-fold-beta-barrel domains of the chromo-like superfamily. Chromodomains lack the first strand of the SH3-fold-beta-barrel, this first strand is altered by insertion in the chromo shadow domains. The chromodomain is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and which appears to play a role in the functional organization of the eukaryotic nucleus. The chromodomain is implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. Chromodomain-containing proteins include: i) those having an N-terminal chromodomain followed by a related chromo shadow domain, such as Drosophila and human heterochromatin protein Su(var)205 (HP1), and mammalian modifier 1 and 2; ii) those having a single chromodomain, such as Drosophila protein Polycomb (Pc), mammalian modifier 3, human Mi-2 autoantigen, and several yeast and Caenorhabditis elegans proteins of unknown function; iii) those having paired tandem chromodomains, such as mammalian DNA-binding/helicase proteins CHD-1 to CHD-4 and yeast protein CHD1; (iv) and elongation factor eEF3, a member of the ATP-binding cassette (ABC) family of proteins, that serves an essential function in the translation cycle of fungi. eEF3 is a soluble factor lacking a transmembrane domain and having two ABC domains arranged in tandem, with a unique chromodomain inserted within the ABC2 domain. Pssm-ID: 349274 [Multi-domain] Cd Length: 50 Bit Score: 60.57 E-value: 1.12e-11
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| CHROMO | smart00298 | Chromatin organization modifier domain; |
760-816 | 1.28e-11 | ||||||
Chromatin organization modifier domain; Pssm-ID: 214605 [Multi-domain] Cd Length: 55 Bit Score: 60.69 E-value: 1.28e-11
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| dcm | TIGR00675 | DNA-methyltransferase (dcm); All proteins in this family for which functions are known are ... |
829-948 | 5.58e-11 | ||||||
DNA-methyltransferase (dcm); All proteins in this family for which functions are known are DNA-cytosine methyltransferases. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair] Pssm-ID: 273211 [Multi-domain] Cd Length: 315 Bit Score: 65.04 E-value: 5.58e-11
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| DNA_methylase | pfam00145 | C-5 cytosine-specific DNA methylase; |
829-1018 | 2.09e-10 | ||||||
C-5 cytosine-specific DNA methylase; Pssm-ID: 395093 [Multi-domain] Cd Length: 324 Bit Score: 63.49 E-value: 2.09e-10
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| BAH_polybromo | cd04717 | BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human ... |
502-581 | 2.50e-10 | ||||||
BAH, or Bromo Adjacent Homology domain, as present in polybromo and yeast RSC1/2. The human polybromo protein (BAF180) is a component of the SWI/SNF chromatin-remodeling complex PBAF. It is thought that polybromo participates in transcriptional regulation. Saccharomyces cerevisiae RSC1 and RSC2 are part of the 15-subunit nucleosome remodeling RSC complex. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions. Pssm-ID: 240068 Cd Length: 121 Bit Score: 59.14 E-value: 2.50e-10
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| CD_CDY | cd18634 | chromodomain of the Chromodomain Y-like protein family; This group includes the chromodomain ... |
760-814 | 9.22e-09 | ||||||
chromodomain of the Chromodomain Y-like protein family; This group includes the chromodomain found in the mammalian chromodomain Y-like (CDY) protein family, and similar proteins. The human CDY family includes 6 proteins: the genes encoding four of these: two copies of CDY1 (CDY1a, CDY1a) and two copies of CDY2(CDY2a and CDY2b), are located on chromosome Y, and the genes encoding the other two members (CDYL and CDYL2) are located on autosomes. The chromosomal genes are only present in primates, whereas the CDYL and CDYL2 genes exist in most mammalian species. The CDY family proteins contain two functional domains: a chromodomain involved in chromatin binding and a catalytic domain found in many coenzyme A (CoA)- dependent acylation enzymes. CDYL is ubiquitously expressed, whereas CDYL2 shows selective expression in tissues of testis, prostate, spleen, and leukocyte. The CDYL genes are ubiquitously expressed, the CDY genes are only expressed in the testis. Deletion of the CDY1b gene has been shown to be a risk factor for male infertility. Impairments in CDY2 expression could be implicated in the pathogenesis of maturation arrest (a failure of germ cell development). Pssm-ID: 349284 Cd Length: 52 Bit Score: 52.45 E-value: 9.22e-09
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| chromodomain | cd18968 | CHROMO (CHRromatin Organization Modifier) domain; uncharacterized subgroup; The chromodomain ... |
760-814 | 9.70e-09 | ||||||
CHROMO (CHRromatin Organization Modifier) domain; uncharacterized subgroup; The chromodomain is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins. The chromodomain is implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Chromodomains belong to the chromo-like superfamily of SH3-fold-beta-barrel domains which includes chromo shadow domains and chromo barrel domains. Chromodomains differ from these in that they lack the first strand of the SH3-fold-beta-barrel. This first strand is altered by insertion in the chromo shadow domains, and chromo barrel domains are typical SH3-fold-beta-barrel domains with sequence similarity to the canonical chromo domain. Pssm-ID: 349324 Cd Length: 57 Bit Score: 52.35 E-value: 9.70e-09
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| CD_Clr4_like | cd18632 | N-terminal chromodomain of the fission yeast histone methyltransferase Clr4, and similar ... |
760-818 | 5.10e-08 | ||||||
N-terminal chromodomain of the fission yeast histone methyltransferase Clr4, and similar proteins; N-terminal CHRomatin Organization Modifier (chromo) domain of cryptic loci regulator 4 (Clr4), a histone H3 lysine methyltransferase which targets H3K9. Clr4 regulates silencing and switching at the mating-type loci and affects chromatin structure at centromeres. Clr4 is a catalytic component of the rik1-associated E3 ubiquitin ligase complex that shows ubiquitin ligase activity and is required for histone H3K9 methylation. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting swi6/HP1 to methylated histones which leads to transcriptional silencing within centromeric heterochromatin, telomeric regions and at the silent mating-type loci. A chromodomain is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and which appears to play a role in the functional organization of the eukaryotic nucleus. The chromodomain is implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Pssm-ID: 349282 Cd Length: 55 Bit Score: 50.58 E-value: 5.10e-08
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| CD_NC-like | cd18980 | chromodomain of a Tasahii var. asahii CBS 8904 retrotransposon nucleocapsid protein, and ... |
760-814 | 7.18e-08 | ||||||
chromodomain of a Tasahii var. asahii CBS 8904 retrotransposon nucleocapsid protein, and similar proteins; This subgroup includes the CHROMO (CHRromatin Organization Modifier) domain found in Trichosporon asahii var. asahii CBS 8904 retrotransposon nucleocapsid protein, and similar proteins. The chromodomain is implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Pssm-ID: 349336 Cd Length: 56 Bit Score: 50.26 E-value: 7.18e-08
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| CD_MMP8 | cd18633 | chromodomain of M-phase phosphoprotein 8; The chromodomain of M-phase phosphoprotein 8 (MPP8), ... |
761-814 | 1.26e-07 | ||||||
chromodomain of M-phase phosphoprotein 8; The chromodomain of M-phase phosphoprotein 8 (MPP8), a component of the RanBPM-containing large protein complex, binds methylated H3K9. This may in turn recruit the H3K9 methyltransferases GLP and ESET, and DNA methyltransferase 3A to the promoter of the E-cadherin gene, mediating the E-cadherin gene silencing and promoting tumor cell motility and invasion. A chromodomain is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and which appears to play a role in the functional organization of the eukaryotic nucleus. The chromodomain is implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Pssm-ID: 349283 Cd Length: 51 Bit Score: 49.21 E-value: 1.26e-07
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| CD_HP1a_insect | cd18653 | chromodomain of insect HP1a; CHRomatin Organization Modifier (chromo) domain of insect HP1a. ... |
760-814 | 1.23e-06 | ||||||
chromodomain of insect HP1a; CHRomatin Organization Modifier (chromo) domain of insect HP1a. HP1a is a member of the heterochromatin protein family, and is enriched in the heterochromatin and associated with centromeres. HP1 has diverse functions in heterochromatin formation and impacts both gene expression and gene silencing. HP1 has two conserved protein-protein interaction domains, a single N-terminal chromodomain (CD) which can bind to histone proteins via methylated lysine residues, and a related C-terminal chromo shadow domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated non-histone proteins; a flexible hinge region separates the CD and CSD and may bind nucleic acid. HP1 is a highly conserved non-histone chromosomal protein that is evolutionarily conserved from fission yeast to plants and animals. In Drosophila, there are at least five HP1 family proteins, this subgroup includes the CD of Drosophila melanogaster HP1a. Pssm-ID: 349300 Cd Length: 50 Bit Score: 46.56 E-value: 1.23e-06
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| CD_POL_like | cd18972 | chromodomain of a Moniliophthora perniciosa FA553 putative retrotransposon polyprotein, and ... |
761-816 | 5.25e-06 | ||||||
chromodomain of a Moniliophthora perniciosa FA553 putative retrotransposon polyprotein, and similar proteins; This subgroup includes the CHROMO (CHRromatin Organization Modifier) domain found in a Moniliophthora perniciosa FA553 putative retrotelement polyprotein, which includes domains in the following order: a reverse transcriptase, RNase H, and an integrase, here the chromodomain is found at the C-terminus of the integrase domain. The chromodomain, is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related "chromo shadow" domain Pssm-ID: 349328 Cd Length: 50 Bit Score: 44.43 E-value: 5.25e-06
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| CD_HP1_like | cd18631 | chromodomain of heterochromatin protein 1 proteins, including HP1alpha, HP1beta, and HP1gamma; ... |
760-816 | 3.00e-05 | ||||||
chromodomain of heterochromatin protein 1 proteins, including HP1alpha, HP1beta, and HP1gamma; CHRomatin Organization Modifier (chromo) domain of mammalian HP1alpha (Cbx5), HP1beta (Cbx1), HP1gamma (Cbx5), and similar proteins. HP1 has diverse functions in heterochromatin formation and impacts both gene expression and gene silencing. HP1 has two conserved protein-protein interaction domains, a single N-terminal chromodomain (CD) which can bind to histone proteins via methylated lysine residues, and a related C-terminal chromo shadow domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated non-histone proteins; a flexible hinge region separates the CD and CSD and may bind nucleic acid. HP1 is a highly conserved non-histone chromosomal protein that is evolutionarily conserved from fission yeast to plants and animals. There are three human homologs of HP1 proteins: HP1alpha (also known as Cbx5), HP1beta (also known as Cbx1), and HP1gamma (also known as Cbx3). Pssm-ID: 349281 Cd Length: 50 Bit Score: 42.42 E-value: 3.00e-05
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| chromodomain | cd18969 | CHROMO (CHRromatin Organization Modifier) domain; uncharacterized subgroup; for most members ... |
760-814 | 5.99e-05 | ||||||
CHROMO (CHRromatin Organization Modifier) domain; uncharacterized subgroup; for most members of this subgroup, the chromodomain is followed by a chromo shadow domain; The chromodomain is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins. The chromodomain is implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Chromodomains belong to the chromo-like superfamily of SH3-fold-beta-barrel domains which includes chromo shadow domains and chromo barrel domains. Chromodomains differ from these in that they lack the first strand of the SH3-fold-beta-barrel. This first strand is altered by insertion in the chromo shadow domains, and chromo barrel domains are typical SH3-fold-beta-barrel domains with sequence similarity to the canonical chromo domain. For the majority of members of this subgroup, the chromodomain is followed by a chromo shadow domain (CSD). Pssm-ID: 349325 Cd Length: 56 Bit Score: 41.74 E-value: 5.99e-05
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| CD_EhHp1_like | cd18638 | chromodomain of Entamoeba histolytica heterochromatin protein 1, and similar proteins; This ... |
761-814 | 6.12e-05 | ||||||
chromodomain of Entamoeba histolytica heterochromatin protein 1, and similar proteins; This subgroup includes the N-terminal CHRomatin Organization Modifier (chromo) domain of heterochromatin protein 1 (HP1)-like protein from Entamoeba histolytica, and similar proteins. A chromodomain is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and which appears to play a role in the functional organization of the eukaryotic nucleus. The chromodomain is implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Pssm-ID: 349288 Cd Length: 52 Bit Score: 41.86 E-value: 6.12e-05
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| CD_Rhino | cd18630 | chromodomain of Drosophila melanogaster Rhino, and similar proteins; N-terminal CHRomatin ... |
778-814 | 6.57e-05 | ||||||
chromodomain of Drosophila melanogaster Rhino, and similar proteins; N-terminal CHRomatin Organization Modifier (chromo) domain of Drosophila melanogaster Rhino (also known as heterochromatin protein 1-like), and similar proteins. Rhino is a female-specific protein that affects chromosome structure and egg polarity that is required for germline PIWI-interacting RNA (piRNA) production. In Drosophila the RDC (rhino, deadlock, and cutoff) complex, composed of rhino, the protein deadlock (Del) and the Rai1-like transcription termination cofactor cutoff (Cuff) binds to chromatin of dual-strand piRNA clusters, special genomic regions, which encode piRNA precursors. The RDC complex is anchored to H3K9me3-marked chromatin in part via the H3K9me3-binding activity of Rhino, and is required for transcription of piRNA precursors. A chromodomain is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and which appears to play a role in the functional organization of the eukaryotic nucleus. The chromodomain is implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Pssm-ID: 349280 Cd Length: 51 Bit Score: 41.74 E-value: 6.57e-05
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| CD_Chro-like | cd18640 | chromodomain of Drosophila melanogaster chromator chromodomain protein, and similar proteins; ... |
779-814 | 1.25e-04 | ||||||
chromodomain of Drosophila melanogaster chromator chromodomain protein, and similar proteins; This subgroup includes the CHROMO (CHRromatin Organization Modifier) domain found in chromodomain of Drosophila melanogaster chromator (also known as Chriz/Chro) chromodomain protein, and similar proteins. Chromator is a nuclear protein that plays a role in proper spindle dynamics during mitosis. The chromodomain is implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Pssm-ID: 349290 Cd Length: 52 Bit Score: 40.74 E-value: 1.25e-04
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| CD_Tf2-1_POL_like | cd18973 | chromodomain of Rhizoctonia solani AG-1 IB retrotransposable element Tf2 155 kDa protein type ... |
761-816 | 1.66e-04 | ||||||
chromodomain of Rhizoctonia solani AG-1 IB retrotransposable element Tf2 155 kDa protein type 1, and similar proteins; This subgroup includes the CHROMO (CHRromatin Organization Modifier) domain found in Rhizoctonia solani AG-1 IB retrotransposable element Tf2 155 kDa protein type 1 (Tf2-1), and similar proteins. It belongs to the Ty3/gypsy family of long terminal repeat (LTR) retrotransposons. The pol gene in TY3/gypsy elements generally encodes domains in the following order: an aspartyl protease, a reverse transcriptase, RNase H, and an integrase, here the chromodomain is found at the C-terminus of the integrase domain. The chromodomain, is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Pssm-ID: 349329 Cd Length: 50 Bit Score: 40.31 E-value: 1.66e-04
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| BAH_plant_3 | cd04713 | BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH ... |
491-564 | 1.85e-04 | ||||||
BAH, or Bromo Adjacent Homology domain, plant-specific sub-family with unknown function. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions. Pssm-ID: 240064 Cd Length: 146 Bit Score: 42.84 E-value: 1.85e-04
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| BAH_DCM_I | cd04712 | BAH, or Bromo Adjacent Homology domain, as present in DNA (Cytosine-5)-methyltransferases (DCM) ... |
511-616 | 1.91e-04 | ||||||
BAH, or Bromo Adjacent Homology domain, as present in DNA (Cytosine-5)-methyltransferases (DCM) 1. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects on the genome. These effects include transcriptional repression via inhibition of transcription factor binding, the recruitment of methyl-binding proteins and their associated chromatin remodeling factors, X chromosome inactivation, imprinting, and the suppression of parasitic DNA sequences. DNA methylation is also essential for proper embryonic development and is an important player in both DNA repair and genome stability. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions. Pssm-ID: 240063 Cd Length: 130 Bit Score: 42.39 E-value: 1.91e-04
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| BAH_BAHCC1 | cd04714 | BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. ... |
502-581 | 4.15e-04 | ||||||
BAH, or Bromo Adjacent Homology domain, as present in mammalian BAHCC1 and similar proteins. BAHCC1 stands for BAH domain and coiled-coil containing 1. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions. Pssm-ID: 240065 Cd Length: 121 Bit Score: 41.23 E-value: 4.15e-04
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| CD_DDE_transposase_like | cd18978 | chromodomain of Rhizopus microsporus putative DDE transposases, and similar proteins; This ... |
760-816 | 4.29e-04 | ||||||
chromodomain of Rhizopus microsporus putative DDE transposases, and similar proteins; This subgroup includes the CHROMO (CHRromatin Organization Modifier) domain found in Rhizopus microsporus putative DDE transposases, and similar proteins. The chromodomain, is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Pssm-ID: 349334 Cd Length: 52 Bit Score: 39.22 E-value: 4.29e-04
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| CD_HP1gamma_Cbx3 | cd18652 | chromodomain of heterochromatin protein 1 homolog gamma; CHRomatin Organization Modifier ... |
779-816 | 4.42e-04 | ||||||
chromodomain of heterochromatin protein 1 homolog gamma; CHRomatin Organization Modifier (chromo) domain of heterochromatin protein 1 homolog gamma (also known as HP1gamma, Cbx3, and Chromobox 3), and related proteins. HP1gamma is a highly conserved non-histone protein, which is a member of the heterochromatin protein family, and is enriched in the heterochromatin and associated with centromeres. HP1 has two conserved protein-protein interaction domains, a single N-terminal chromodomain (CD) which can bind to histone proteins via methylated lysine residues, and a related C-terminal chromo shadow domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated non-histone proteins; a flexible hinge region separates the CD and CSD and may bind nucleic acid. In addition to being involved in transcriptional silencing in heterochromatin-like complexes, HP1gamma also binds lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the protein may explain the association of heterochromatin with the inner nuclear membrane. HP1gamma is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. HP1 is a highly conserved non-histone chromosomal protein that is evolutionarily conserved from fission yeast to plants and animals. There are three human homologs of HP1 proteins: HP1alpha (also known as Cbx5), HP1beta (also known as Cbx1), and HP1gamma. Pssm-ID: 349299 Cd Length: 50 Bit Score: 39.22 E-value: 4.42e-04
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| CD_HP1beta_Cbx1 | cd18650 | chromodomain of heterochromatin protein 1 homolog beta; CHRomatin Organization Modifier ... |
760-816 | 6.45e-04 | ||||||
chromodomain of heterochromatin protein 1 homolog beta; CHRomatin Organization Modifier (chromo) domain of heterochromatin protein 1 homolog beta (also known as HP1beta, CBX1, and chromobox 1), and related proteins. HP1beta is a highly conserved non-histone protein, which is a member of the heterochromatin protein family, and is enriched in the heterochromatin and associated with centromeres. HP1 has two conserved protein-protein interaction domains, a single N-terminal chromodomain (CD) which can bind to histone proteins via methylated lysine residues, and a related C-terminal chromo shadow domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated non-histone proteins; a flexible hinge region separates the CD and CSD and may bind nucleic acid. HP1 is a highly conserved non-histone chromosomal protein that is evolutionarily conserved from fission yeast to plants and animals. There are three human homologs of HP1 proteins: HP1alpha (also known as Cbx5), HP1beta, and HP1gamma (also known as Cbx3). Pssm-ID: 349297 Cd Length: 50 Bit Score: 38.77 E-value: 6.45e-04
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| CD_SUV39H1_like | cd18639 | chromodomain of histone methyltransferase SUV39H1, and similar proteins; CHRomatin ... |
761-814 | 8.92e-04 | ||||||
chromodomain of histone methyltransferase SUV39H1, and similar proteins; CHRomatin Organization Modifier (chromo) domain of human SUV39H1, a histone lysine methyltransferase (HMT) which catalyzes di- and tri-methylation of lysine 9 of histone H3 (H3K9me2/3), leading to heterochromatin formation and gene silencing. H3K9me2/3 represents a specific mark for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3, and/or CBX5) proteins to methylated histones. SUV39H1 mainly functions in heterochromatin regions. The human SUV39H1/2, histone H3K9 methyltransferases, are the mammalian homologs of Drosophila Su(var)3-9 and Schizosaccharomyces pombe Clr4. SUV39H1 contains a chromodomain at its N-terminus and a SET domain at its C-terminus. Although the SET domain performs the catalytic activity, the chromodomain of SUV39H1 is essential for the catalytic activity of SUV39H1. A chromodomain is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and which appears to play a role in the functional organization of the eukaryotic nucleus. The chromodomain is implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Pssm-ID: 349289 Cd Length: 49 Bit Score: 38.27 E-value: 8.92e-04
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| CD_HP1alpha_Cbx5 | cd18651 | chromodomain of heterochromatin protein 1 homolog alpha; CHRomatin Organization Modifier ... |
760-816 | 1.46e-03 | ||||||
chromodomain of heterochromatin protein 1 homolog alpha; CHRomatin Organization Modifier (chromo) domain of heterochromatin protein 1 homolog alpha (also known as HP1alpha, Cbx5, and Chromobox 5), and related proteins. HP1alpha has diverse functions in heterochromatin formation, gene regulation, and mitotic progression, and forms complex networks of gene, RNA, and protein interactions. HP1 has two conserved protein-protein interaction domains, a single N-terminal chromodomain (CD) which can bind to histone proteins via methylated lysine residues, and a related C-terminal chromo shadow domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated non-histone proteins; a flexible hinge region separates the CD and CSD and may bind nucleic acid. HP1 is a highly conserved non-histone chromosomal protein that is evolutionarily conserved from fission yeast to plants and animals. There are three human homologs of HP1 proteins: HP1alpha, HP1beta (also known as Cbx1), and HP1gamma (also known as Cbx3). Pssm-ID: 349298 Cd Length: 50 Bit Score: 37.66 E-value: 1.46e-03
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| CD_POL_like | cd18976 | chromodomain of uncharacterized putative retroelement polyprotein proteins; This subgroup ... |
761-814 | 2.22e-03 | ||||||
chromodomain of uncharacterized putative retroelement polyprotein proteins; This subgroup includes the CHROMO (CHRromatin Organization Modifier) domain found in uncharacterized putative retrotransposon proteins, and similar proteins. The chromodomain, is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Pssm-ID: 349332 Cd Length: 51 Bit Score: 37.16 E-value: 2.22e-03
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| CD_POL_like | cd18977 | chromodomain of a Rhizoctonia solani AG-3 Rhs1AP polyprotein, and similar proteins; This ... |
760-814 | 2.63e-03 | ||||||
chromodomain of a Rhizoctonia solani AG-3 Rhs1AP polyprotein, and similar proteins; This subgroup includes the CHROMO (CHRromatin Organization Modifier) domain found in a Rhizoctonia solani AG-3 Rhs1AP, a putative Ty3/Gypsy polyprotein/retrotransposon which includes a protease, a reverse transcriptase, a ribonuclease H, and an integrase domain, in that order, with a chromodomain at the C-terminus of the integrase domain. The chromodomain, is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Pssm-ID: 349333 Cd Length: 57 Bit Score: 37.08 E-value: 2.63e-03
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| CD_POL_like | cd18979 | chromodomain of a Zea maize putative metaviridae (gypsy-type) retrotransposon polyproteins ... |
777-804 | 3.13e-03 | ||||||
chromodomain of a Zea maize putative metaviridae (gypsy-type) retrotransposon polyproteins (Z195D10.9), and similar proteins; This subgroup includes the CHROMO (CHRromatin Organization Modifier) domain found in Zea maize Z195D10.9 protein, and other putative TY3/gypsy retrotransposon polyproteins. The pol gene in TY3/gypsy elements generally encodes domains in the following order: an aspartyl protease, a reverse transcriptase, RNase H, and an integrase, here the chromodomain is found at the C-terminus of the integrase domain. The chromodomain, is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Pssm-ID: 349335 Cd Length: 48 Bit Score: 36.70 E-value: 3.13e-03
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| CD_POL_like | cd18974 | chromodomain of Penicillium solitum protein PENSOL_c198G03123; This subgroup includes the ... |
761-814 | 3.65e-03 | ||||||
chromodomain of Penicillium solitum protein PENSOL_c198G03123; This subgroup includes the CHROMO (CHRromatin Organization Modifier) domain found in Penicillium solitum protein PENSOL_c198G03123 a putative polyprotein from a Ty3/Gypsy long terminal repeat (LTR) retroelement. The pol gene in TY3/gypsy elements generally encodes domains in the following order: an aspartyl protease, a reverse transcriptase, RNase H, and an integrase, here the chromodomain is found at the C-terminus of the integrase domain. The chromodomain, is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Pssm-ID: 349330 Cd Length: 50 Bit Score: 36.69 E-value: 3.65e-03
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| CD_Chp1_like | cd18636 | chromodomain of chromodomain-containing protein 1, and similar proteins; CHRomatin ... |
761-814 | 5.32e-03 | ||||||
chromodomain of chromodomain-containing protein 1, and similar proteins; CHRomatin Organization Modifier (chromo) domain of chromodomain-containing protein 1 (CHp1), and similar proteins. Chp1 is needed for RNA interference-dependent heterochromatin formation in fission yeast. Chp1 is a member of the RNA-induced transcriptional silencing (RITS) complex which maintains the heterochromatin regions. The chromodomain of the Chp1 component binds the histone H3 lysine 9 methylated tail (H3K9me) and the core of the nucleosome. A chromodomain is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins, and which appears to play a role in the functional organization of the eukaryotic nucleus. The chromodomain is implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Pssm-ID: 349286 Cd Length: 52 Bit Score: 36.27 E-value: 5.32e-03
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| BAH_Dnmt1_I | cd04760 | BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5) ... |
506-586 | 6.96e-03 | ||||||
BAH, or Bromo Adjacent Homology domain, first copy present in DNA (Cytosine-5)-methyltransferases from Bilateria, Dnmt1 and similar proteins. DNA methylation, or the covalent addition of a methyl group to cytosine within the context of the CpG dinucleotide, has profound effects on the genome. These effects include transcriptional repression via inhibition of transcription factor binding, the recruitment of methyl-binding proteins and their associated chromatin remodeling factors, X chromosome inactivation, imprinting, and the suppression of parasitic DNA sequences. DNA methylation is also essential for proper embryonic development and is an important player in both DNA repair and genome stability. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions. Pssm-ID: 240107 Cd Length: 124 Bit Score: 37.83 E-value: 6.96e-03
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| CD_HP1_like | cd18960 | chromodomain of heterochromatin protein 1 proteins, including HP1alpha, HP1beta, and HP1gamma; ... |
761-814 | 7.07e-03 | ||||||
chromodomain of heterochromatin protein 1 proteins, including HP1alpha, HP1beta, and HP1gamma; uncharacterized subgroup; CHRomatin Organization Modifier (chromo) domain of mammalian HP1alpha (Cbx5), HP1beta (Cbx1), HP1gamma (Cbx5), and similar proteins. HP1 has diverse functions in heterochromatin formation and impacts both gene expression and gene silencing. HP1 has two conserved protein-protein interaction domains, a single N-terminal chromodomain (CD) which can bind to histone proteins via methylated lysine residues, and a related C-terminal chromo shadow domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated non-histone proteins; a flexible hinge region separates the CD and CSD and may bind nucleic acid. HP1 is a highly conserved non-histone chromosomal protein that is evolutionarily conserved from fission yeast to plants and animals. There are three human homologs of HP1 proteins: HP1alpha (also known as Cbx5), HP1beta (also known as Cbx1), and HP1gamma (also known as Cbx3). Pssm-ID: 349316 Cd Length: 51 Bit Score: 36.00 E-value: 7.07e-03
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| BAH_Orc1p_like | cd04715 | BAH, or Bromo Adjacent Homology domain, as present in the Schizosaccharomyces pombe homolog of ... |
493-585 | 8.29e-03 | ||||||
BAH, or Bromo Adjacent Homology domain, as present in the Schizosaccharomyces pombe homolog of Saccharomyces cerevisiae Orc1p and similar proteins. Orc1 is part of the Yeast Sir1-origin recognition complex, the Orc1p BAH doman functions in epigenetic silencing. BAH domains are found in a variety of proteins playing roles in transcriptional silencing and the remodeling of chromatin. It is assumed that in most or all of these instances the BAH domain mediates protein-protein interactions. Pssm-ID: 240066 Cd Length: 159 Bit Score: 38.25 E-value: 8.29e-03
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| chromodomain | cd18964 | CHROMO (CHRromatin Organization Modifier) domain; uncharacterized subgroup; The chromodomain ... |
776-816 | 8.41e-03 | ||||||
CHROMO (CHRromatin Organization Modifier) domain; uncharacterized subgroup; The chromodomain is a conserved region of about 50 amino acids, found in a variety of chromosomal proteins. The chromodomain is implicated in the binding, of the proteins in which it is found, to methylated histone tails and maybe RNA. A chromodomain may occur as a single instance, in a tandem arrangement, or followed by a related chromo shadow domain. Chromodomains belong to the chromo-like superfamily of SH3-fold-beta-barrel domains which includes chromo shadow domains and chromo barrel domains. Chromodomains differ from these in that they lack the first strand of the SH3-fold-beta-barrel. This first strand is altered by insertion in the chromo shadow domains, and chromo barrel domains are typical SH3-fold-beta-barrel domains with sequence similarity to the canonical chromo domain. Pssm-ID: 349320 Cd Length: 54 Bit Score: 35.77 E-value: 8.41e-03
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