|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
5-813 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1529.19 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 5 PQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDS 84
Cdd:PRK05560 1 EGDRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 85 SIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARF 164
Cdd:PRK05560 81 AVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 165 PNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMR 244
Cdd:PRK05560 161 PNLLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVMR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 245 SRAVIEERgGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSlRTGVRVVIDVRKDANASVILNNLYKQ 324
Cdd:PRK05560 241 AKAEIEEI-KGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESD-RDGMRIVIELKRDAVPEVVLNNLYKH 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 325 TPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTD 404
Cdd:PRK05560 319 TQLQTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTP 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 405 KVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRFGDDR 484
Cdd:PRK05560 399 AEAKEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGDPR 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 485 RTEIQLGGfEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLFFTNK 564
Cdd:PRK05560 479 RTEIIEGE-GDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFTNR 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 565 GRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLEsEDNFLVFATKRGVVKRSALSNFSRINRNGKIAIS 644
Cdd:PRK05560 558 GRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFD-DDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAIN 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 645 FREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSvDEVLVVTENGYG 724
Cdd:PRK05560 637 LDEGDELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVRGIKLREGDEVVSMDVVREDS-QEILTVTENGYG 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 725 KRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNVGVIIRLDVADISQNGRAAQGVRLIRLGDDQFV 804
Cdd:PRK05560 716 KRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLIRTRVSEISITGRNTQGVRLIRLDEGDKV 795
|
....*....
gi 616687109 805 STVAKVKED 813
Cdd:PRK05560 796 VSVARVAEE 804
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-808 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1448.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 1 MAELPQ-SRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYH 79
Cdd:COG0188 1 MSDPPPaERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 80 PHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSV 159
Cdd:COG0188 81 PHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 160 LPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRG 239
Cdd:COG0188 161 LPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 240 SIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSlRTGVRVVIDVRKDANASVILN 319
Cdd:COG0188 241 SIRVRAKAEIEELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESD-RDGMRIVIELKRDANPEVVLN 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 320 NLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIR 399
Cdd:COG0188 320 QLYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIR 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 400 ESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDR 479
Cdd:COG0188 400 ASKDPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELLEIKKK 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 480 FGDDRRTEIQLGGfEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVL 559
Cdd:COG0188 480 YGDERRTEIEEAE-GEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDFVEHLFVASTHDTLL 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 560 FFTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLEsEDNFLVFATKRGVVKRSALSNFSRINRNG 639
Cdd:COG0188 559 FFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFD-EDKYLLFATKKGTVKKTPLSDFSNIRKNG 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 640 KIAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANsvDEVLVVT 719
Cdd:COG0188 638 IIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTARGVRGIRLKEGDEVVGMAVVDEE--DDLLTVT 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 720 ENGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNVGVIIRLDVADISQNGRAAQGVRLIRLG 799
Cdd:COG0188 716 ENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNTQGVRLIRLD 795
|
....*....
gi 616687109 800 DDQFVSTVA 808
Cdd:COG0188 796 EGDKVVSVA 804
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
9-812 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1257.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 9 INERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYE 88
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 89 AMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLL 168
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 169 ANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAV 248
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 249 IEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSlRTGVRVVIDVRKDANASVILNNLYKQTPLQ 328
Cdd:TIGR01063 241 IEEDSKGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESD-REGIRIVIELKRDAVAEVVLNNLYKQTQLQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 329 TSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAM 408
Cdd:TIGR01063 320 VSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 409 ESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRFGDDRRTEI 488
Cdd:TIGR01063 400 TRLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPRRTEI 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 489 QLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLFFTNKGRVY 568
Cdd:TIGR01063 480 VYDESEDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVY 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 569 KLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLEsEDNFLVFATKRGVVKRSALSNFSRINRNGKIAISFRED 648
Cdd:TIGR01063 560 WLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFD-DGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKLDDG 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 649 DELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSvdEVLVVTENGYGKRTP 728
Cdd:TIGR01063 639 DELISVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIKLKNEDFVVSLLVVSEES--YLLIVTENGYGKRTS 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 729 VNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNVGVIIRLDVADISQNGRAAQGVRLIRLGDDQFVSTVA 808
Cdd:TIGR01063 717 IEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLIRLDEDDKLVSVS 796
|
....
gi 616687109 809 KVKE 812
Cdd:TIGR01063 797 KVAK 800
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
31-476 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 715.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 31 VARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNF 110
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 111 GSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTE 190
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 191 LINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERgGGRQRIVVTEIPFQVNK 270
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDD-EGRNTIEITELPYQVNK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 271 ARMIEKIAELVRDKKIDGITDLRDETSlRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALV-NGRPKLINLK 349
Cdd:cd00187 240 AKLKEKIAELVKDKKIEGISDVRDESD-REGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDpNGRPKKLNLK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 350 EALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMR 429
Cdd:cd00187 319 EILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSSDEAKKALIEELEKLGFSEIQADAILDMR 398
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 616687109 430 LRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEI 476
Cdd:cd00187 399 LRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
12-466 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 667.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 12 RNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMV 91
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 92 RMAQDFSYRYPLVDGQGNFGSM-DGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLAN 170
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 171 GASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRrayetgrgsiqMRSRAVIE 250
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIVGPGKYV-----------VRGKIEIE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 251 ErgggRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTS 330
Cdd:smart00434 230 D----DNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDESHDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQTT 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 331 FGVNMIALV-NGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAK-DRAHILEGLRIALDHIDEIISTIRES-DTDKVA 407
Cdd:smart00434 306 FSINMLALFdNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSkDLAKEA 385
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 616687109 408 MESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLL 466
Cdd:smart00434 386 KEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
33-473 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 648.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 33 RALPDVRDGLKPVHRRILYGLNEQgMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGS 112
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFEL-LNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 113 -MDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTEL 191
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 192 INGVLSLSKNPDISIaeLMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEErgggRQRIVVTEIPFQVNKA 271
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED----RKTIVITELPYGVWTS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 272 RMIEKIAELVRDKKIDGITDLRDETSlrTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEA 351
Cdd:pfam00521 234 DLIEKIEELVKNGKIKGISDIRDESD--RGVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKEI 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 352 LVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRfkLSEKQAQAILDMRLR 431
Cdd:pfam00521 312 LKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIEE--LSEIQADYLLDMRLR 389
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 616687109 432 RLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDEL 473
Cdd:pfam00521 390 RLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEEL 431
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
5-813 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1529.19 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 5 PQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDS 84
Cdd:PRK05560 1 EGDRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 85 SIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARF 164
Cdd:PRK05560 81 AVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 165 PNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMR 244
Cdd:PRK05560 161 PNLLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGGIILGRSGIREAYRTGRGSIVMR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 245 SRAVIEERgGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSlRTGVRVVIDVRKDANASVILNNLYKQ 324
Cdd:PRK05560 241 AKAEIEEI-KGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESD-RDGMRIVIELKRDAVPEVVLNNLYKH 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 325 TPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTD 404
Cdd:PRK05560 319 TQLQTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASPTP 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 405 KVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRFGDDR 484
Cdd:PRK05560 399 AEAKEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGDPR 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 485 RTEIQLGGfEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLFFTNK 564
Cdd:PRK05560 479 RTEIIEGE-GDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFTNR 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 565 GRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLEsEDNFLVFATKRGVVKRSALSNFSRINRNGKIAIS 644
Cdd:PRK05560 558 GRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFD-DDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAIN 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 645 FREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSvDEVLVVTENGYG 724
Cdd:PRK05560 637 LDEGDELIGVRLTDGDDDILLATKNGKAIRFPESDVRPMGRTARGVRGIKLREGDEVVSMDVVREDS-QEILTVTENGYG 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 725 KRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNVGVIIRLDVADISQNGRAAQGVRLIRLGDDQFV 804
Cdd:PRK05560 716 KRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLIRTRVSEISITGRNTQGVRLIRLDEGDKV 795
|
....*....
gi 616687109 805 STVAKVKED 813
Cdd:PRK05560 796 VSVARVAEE 804
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-808 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1448.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 1 MAELPQ-SRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYH 79
Cdd:COG0188 1 MSDPPPaERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 80 PHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSV 159
Cdd:COG0188 81 PHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 160 LPARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRG 239
Cdd:COG0188 161 LPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIVGREGIREAYETGRG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 240 SIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSlRTGVRVVIDVRKDANASVILN 319
Cdd:COG0188 241 SIRVRAKAEIEELKRGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESD-RDGMRIVIELKRDANPEVVLN 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 320 NLYKQTPLQTSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIR 399
Cdd:COG0188 320 QLYKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIR 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 400 ESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDR 479
Cdd:COG0188 400 ASKDPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELLEIKKK 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 480 FGDDRRTEIQLGGfEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVL 559
Cdd:COG0188 480 YGDERRTEIEEAE-GEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDFVEHLFVASTHDTLL 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 560 FFTNKGRVYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLEsEDNFLVFATKRGVVKRSALSNFSRINRNG 639
Cdd:COG0188 559 FFTNKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFD-EDKYLLFATKKGTVKKTPLSDFSNIRKNG 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 640 KIAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANsvDEVLVVT 719
Cdd:COG0188 638 IIAINLKEGDELVGVALTDGDDDVLLATSNGKAIRFPESDVRPMGRTARGVRGIRLKEGDEVVGMAVVDEE--DDLLTVT 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 720 ENGYGKRTPVNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNVGVIIRLDVADISQNGRAAQGVRLIRLG 799
Cdd:COG0188 716 ENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNTQGVRLIRLD 795
|
....*....
gi 616687109 800 DDQFVSTVA 808
Cdd:COG0188 796 EGDKVVSVA 804
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
9-812 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1257.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 9 INERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYE 88
Cdd:TIGR01063 1 IVPVNIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 89 AMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLL 168
Cdd:TIGR01063 81 TLVRMAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 169 ANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAV 248
Cdd:TIGR01063 161 VNGSSGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 249 IEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSlRTGVRVVIDVRKDANASVILNNLYKQTPLQ 328
Cdd:TIGR01063 241 IEEDSKGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESD-REGIRIVIELKRDAVAEVVLNNLYKQTQLQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 329 TSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAM 408
Cdd:TIGR01063 320 VSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 409 ESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRFGDDRRTEI 488
Cdd:TIGR01063 400 TRLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPRRTEI 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 489 QLGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLFFTNKGRVY 568
Cdd:TIGR01063 480 VYDESEDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVY 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 569 KLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLEsEDNFLVFATKRGVVKRSALSNFSRINRNGKIAISFRED 648
Cdd:TIGR01063 560 WLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFD-DGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKLDDG 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 649 DELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANSvdEVLVVTENGYGKRTP 728
Cdd:TIGR01063 639 DELISVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRAARGVRGIKLKNEDFVVSLLVVSEES--YLLIVTENGYGKRTS 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 729 VNDYRLSNRGGKGIKTATITERNGNVVCITTVTGEEDLMIVTNVGVIIRLDVADISQNGRAAQGVRLIRLGDDQFVSTVA 808
Cdd:TIGR01063 717 IEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLIRLDEDDKLVSVS 796
|
....
gi 616687109 809 KVKE 812
Cdd:TIGR01063 797 KVAK 800
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
1-743 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 928.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 1 MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHP 80
Cdd:PRK05561 2 PDMSMLEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 81 HGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL 160
Cdd:PRK05561 82 HGDSSIYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 161 PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLIL-GKSGIRRAYETGRG 239
Cdd:PRK05561 162 PARFPNLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDATLEELMEFVPGPDFPTGGEIItGRDGIRKAYETGRG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 240 SIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKD-ANASVIL 318
Cdd:PRK05561 242 SIRVRARWEIEDLAGGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDRENPVRIVIEPKSNrVDPEALM 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 319 NNLYKQTPLQTSFGVNMIAL-VNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIIST 397
Cdd:PRK05561 322 NHLFATTDLESSYRVNMNAIgLDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEVIRI 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 398 IRESDTDKvamESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIR 477
Cdd:PRK05561 402 IRESDEPK---ANLMARFDLSEIQAEAILELRLRRLAKLEEIEIRKEQDELRKEIAELEAILASERKLRKLIKKELKADA 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 478 DRFGDDRRTEIQLGGFEDLEDE-DLIPEEQIVITLSHNNYIKRlpvstyraqnRGGRGV--QGMNTLEEDFVSQLVTLST 554
Cdd:PRK05561 479 KKFGDPRRTPIEEAEEAIAIDEeALIPDEPVTVVLSKKGWVRR----------AKGHSIdaSGLSFKEGDSLLFAFEART 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 555 HDHVLFFTNKGRVYKLKGYEVPELSRQskGIPVVNAIELENDEVISTMIAVKdlesEDNFLVFATKRGVVKRSALSNFSR 634
Cdd:PRK05561 549 TDKLLLFTSTGRVYSLPVHELPSARGD--GEPLTGLVDLAPGEEIVHVLAFD----PDQKLLLASSAGYGFVVTLEDLVA 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 635 INRNGKIAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRPLGRtATGVKGITLREGDEVVgLDVAHANSVDE 714
Cdd:PRK05561 623 RTRAGKAVINLKDGDEVLPPVPVEDDDHLAAITSNGRLLVFPLSELPELGK-GKGVKLINLPKDDDGL-VDLRVLNPEDG 700
|
730 740 750
....*....|....*....|....*....|.
gi 616687109 715 VLVVTE-NGYGKRTPVN-DYRLSNRGGKGIK 743
Cdd:PRK05561 701 LVLLTAgKRKLKLKPSElEKYRGKRARRGRL 731
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
31-476 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 715.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 31 VARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNF 110
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 111 GSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTE 190
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 191 LINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERgGGRQRIVVTEIPFQVNK 270
Cdd:cd00187 161 VIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDD-EGRNTIEITELPYQVNK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 271 ARMIEKIAELVRDKKIDGITDLRDETSlRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALV-NGRPKLINLK 349
Cdd:cd00187 240 AKLKEKIAELVKDKKIEGISDVRDESD-REGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDpNGRPKKLNLK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 350 EALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMR 429
Cdd:cd00187 319 EILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSSDEAKKALIEELEKLGFSEIQADAILDMR 398
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 616687109 430 LRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEI 476
Cdd:cd00187 399 LRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| PRK13979 |
PRK13979 |
DNA topoisomerase IV subunit A; Provisional |
18-804 |
0e+00 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain] Cd Length: 957 Bit Score: 711.88 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 18 MRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDF 97
Cdd:PRK13979 22 MPENYLPYAVEVAKDRALPDVRDGLKPVHRRILYGAYMLKAFPDKPYYKSARIVGDILGKYHPHGDSSVYDAMVILAQDF 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 98 SYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAV 177
Cdd:PRK13979 102 TTRMPLIDGHGNWGSIDGDSAAAMRYTEARLTPIAMEMLRDIDKDVVNMVDNYSDSEKEPEVLPARYPNLLVNGAFGIAV 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 178 GMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQ 257
Cdd:PRK13979 182 GLATNIPPHNLKEVIDGTLAYIDNNEITTKELMNYIKGPDLPTGGILIGKKSLLSAYETGEGKVTLRAKTKIEKLENGRL 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 258 RIVVTEIPFQVNKARMIEKIAELVRDKK----IDGITDLRDEtSLRTGVRVVIDVRKDAN---ASVILNNLYKQTPLQTS 330
Cdd:PRK13979 262 GIVITEFPYRRNKAKLLQTISEMTADKKhskaLENISDIRDE-SDRNGIRAVIEFKKSADedvAEKVLKYLYKKTDLQCN 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 331 FGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMES 410
Cdd:PRK13979 341 ISFNMVALADGKPETMGLKTMLKHYVEHQKEVVTRRTKKELEIAEKRFHIVEGFIKAIGIMDEIIKTIRSSKSKKDASEN 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 411 LQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRFGDDRRTEIql 490
Cdd:PRK13979 421 LIEKFGFTDEQAEAILELMLYRLTGLEIVAFEKEYKELEKLIKKLTKILSSEKELLKVIKKELKEVKEKYGDERRTSI-- 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 491 ggFEDLED-----EDLIPEEQIVITLSHNNYIKRLPVSTYraqNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLFFTNKG 565
Cdd:PRK13979 499 --IEDDEKakidvEELIVVEDVVITLSNEGFIKRIPLKSY---NRSNSNVEDIEYREGDFNKFLIQSNTKDTLLIFTDKG 573
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 566 RVYKLKGYEVPELSRQSKGI---PVVNAIELENDEVIsTMIAVKDLESEDNFlVFATKRGVVKRSALSNFSRInrNGKI- 641
Cdd:PRK13979 574 NMYQIKGINIPEFKWKEKGErldEIIKGIDLESEKII-EAYSIEDFTPQKDF-IFITDSGGIKKTSLDKFVTN--YTKLm 649
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 642 AISFREDDELIAVRLTSGQED---ILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVA----------- 707
Cdd:PRK13979 650 ALKLKKGEKLIKVKLVDRTREekfIKIKTKKGLSFTVEEPELEPVDRNIIGYQLFDLLPNDSIKKVDFCdnyeykefyvn 729
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 708 --------------------HANSVDEVLVVTENGYGKRTPVndYRLSNRGGKGIKTATIT---ERNGNVVCITTVTG-- 762
Cdd:PRK13979 730 inkkgiikisdkdnkssisvFTNSSKNLLIFSDEGKVYKIPA--FMLQNIKNEGINISALTgdfEKDEKIIKIISIFEfe 807
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 763 --------------------------------------------------EEDLMIVTNVGVIIRLDVADISQNGRAAQG 792
Cdd:PRK13979 808 edlsiyffskkglvkktllnefkgegnstqaykfkhkedelvnvdikeheEKNILLITEKGMAIRFKSEAVNPMGKIASG 887
|
890
....*....|..
gi 616687109 793 VRLIRLGDDQFV 804
Cdd:PRK13979 888 VTGISLKDEDKV 899
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
12-466 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 667.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 12 RNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMV 91
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 92 RMAQDFSYRYPLVDGQGNFGSM-DGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLAN 170
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRlDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 171 GASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRrayetgrgsiqMRSRAVIE 250
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIVGPGKYV-----------VRGKIEIE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 251 ErgggRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTS 330
Cdd:smart00434 230 D----DNTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDESHDRTGVRIVIELKRGAMAEVVLNGLYKLTKLQTT 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 331 FGVNMIALV-NGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAK-DRAHILEGLRIALDHIDEIISTIRES-DTDKVA 407
Cdd:smart00434 306 FSINMLALFdNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSkDLAKEA 385
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 616687109 408 MESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLL 466
Cdd:smart00434 386 KEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
33-473 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 648.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 33 RALPDVRDGLKPVHRRILYGLNEQgMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDFSYRYPLVDGQGNFGS 112
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFEL-LNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 113 -MDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPHNLTEL 191
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 192 INGVLSLSKNPDISIaeLMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEErgggRQRIVVTEIPFQVNKA 271
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED----RKTIVITELPYGVWTS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 272 RMIEKIAELVRDKKIDGITDLRDETSlrTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVNGRPKLINLKEA 351
Cdd:pfam00521 234 DLIEKIEELVKNGKIKGISDIRDESD--RGVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGLKEI 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 352 LVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRfkLSEKQAQAILDMRLR 431
Cdd:pfam00521 312 LKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIEE--LSEIQADYLLDMRLR 389
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 616687109 432 RLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDEL 473
Cdd:pfam00521 390 RLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEEL 431
|
|
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
18-750 |
0e+00 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 625.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 18 MRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIYEAMVRMAQDF 97
Cdd:TIGR01061 10 FGESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYDAMVRMSQDW 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 98 SYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAV 177
Cdd:TIGR01061 90 KNNWTLVEMHGNNGSIDGDNAAAMRYTEARLSLIASELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLLINGATGIAA 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 178 GMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQ 257
Cdd:TIGR01061 170 GYATNIPPHNLNEVIDALIYRIDHPNCSVDKLMEIVKGPDFPTGGIIQGEDGISKAYETGKGKFIIRAKIEIEVNKNGLN 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 258 RIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSlRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIA 337
Cdd:TIGR01061 250 QIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRDESD-RNGIRIIIELKKDANAEKILNFLFKHTDLQINYNFNMVA 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 338 LVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDTDKVAMESLQQRFKL 417
Cdd:TIGR01061 329 IANRTPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRSSEDKSDAKENLIDNFKF 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 418 SEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRFGDDRRTEIQLGGFE-DL 496
Cdd:TIGR01061 409 TENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLEQIIASEKARNKLLKKQLEEYKKQFAQQRRSQIEDFINQiKI 488
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 497 EDEDLIPEEQIVITLSHNNYIKRLPVSTYRAQNRGGRGVQgmntlEEDFVSQLVTLSTHDHVLFFTNKGRVYKLKGYEVP 576
Cdd:TIGR01061 489 NESELIENEDYYVLITKAGYIKRTSNRSFASSKYTDFGSK-----DDDILFAQTIANTTDQILIFTSLGNIINIPVHKLA 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 577 ELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVVKRSALSNFSrINRNGK--IAISFREDDELIAV 654
Cdd:TIGR01061 564 DIRWKDLGEHLSNKITFDENETIVFVGTMNEFDVDQPILVLASKLGMVKRIELTELN-IKRNSKatLCIKLKDKDHLISA 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 655 RLTSGQEDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDVAHANsvDEVLVVTENGYGKRTPVNDYRL 734
Cdd:TIGR01061 643 FLQQKDKLICLVSDLGYALVFHTNEIPVVGAKAAGVKGMKLKEDDQVKSGVIFEAN--ESLVLLTQRGSVKRLSISELVV 720
|
730
....*....|....*.
gi 616687109 735 SNRGGKGIKTATITER 750
Cdd:TIGR01061 721 TSRAATGKKLLPLKKK 736
|
|
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
8-705 |
0e+00 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 559.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 8 RINERNITSEmreSFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDSSIY 87
Cdd:TIGR01062 3 NIDLGNFTEE---AYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 88 EAMVRMAQDFSYRYPLVDGQGNFGSMDG-DGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVLPARFPN 166
Cdd:TIGR01062 80 EAMVLMAQPFSYRYPLVDGQGNWGAPDDpKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 167 LLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDFPTAGLILGK-SGIRRAYETGRGSIQMRS 245
Cdd:TIGR01062 160 ILLNGTTGIAVGMATDIPPHNLHELADAALYLIDNPKAGLDDILNIVQGPDFPTEAEIIDKaEEIRKIYETGRGSFRMRA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 246 RAVIEErgggrQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDA-NASVILNNLYKQ 324
Cdd:TIGR01062 240 RWKKED-----GQIVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESDHENPIRVVIVPRSNRvDPDIVMEHLFAT 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 325 TPLQTSFGVNMIAL-VNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHIDEIISTIRESDT 403
Cdd:TIGR01062 315 TDLEKSYRLNMNMIgLDNVPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIREEDE 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 404 DKVAmesLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADEEVLLQLVRDELTEIRDRFGDD 483
Cdd:TIGR01062 395 PKTI---LMERFKLSAIQAEAILNLRLRHLAKLEEHAIIDEQSELEKERAILEKILKSERELNQLVKKEIQADATKYGLA 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 484 RRTEIQ-LGGFEDLEDEDLIPEEQIVITLSHNNYIKRLPVSTYRAqnrggrgvQGMNTLEEDFVSQLVTLSTHDHVLFFT 562
Cdd:TIGR01062 472 RRSSLEeREEAKQVSEIDMIPKEPVTIILSKMGWVRSAKGHDIDL--------STLKYKAGDSEKAIIEGKSNQKVVFID 543
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 563 NKGRVYKLKGYEVPelSRQSKGIPVVNAIELENDEVISTMIavkdLESEDNFLVFATKRGvvkRSALSNFSRI---NRNG 639
Cdd:TIGR01062 544 STGRSYALDPDNLP--SARGQGEPLTGKLLLPIGATITNIL----MYSPNQLLLMASDAG---YGFLCNFNDLiarNKAG 614
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 616687109 640 KIAISFREDDELIAVRLTSGQEDILIG-TSHASLIRFPESTLrPLGRTATGVKGITLREGDEVVGLD 705
Cdd:TIGR01062 615 KALINLPENASVIAPLPVNGDSDMIAAiTEAGRMLVFPIDDL-PELSKGKGNKLIRIPSANAKRGED 680
|
|
| PRK09631 |
PRK09631 |
DNA topoisomerase IV subunit A; Provisional |
13-490 |
1.50e-74 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain] Cd Length: 635 Bit Score: 256.56 E-value: 1.50e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 13 NITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGmtpDKSYKKSARIVGDVMgKYHPHGDSSIYEAMVR 92
Cdd:PRK09631 3 DIKTLFKDNFLQYASYVIKDRAIPDVIDGLKPVQRRILHSLFEMH---DGKFHKVANVVGNTM-KYHPHGDASIYEALVN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 93 MA-QDFsyrypLVDGQGNFGSM-DGDGAAAMRYTEARMTKITLELLrdINKDTIDFIDNYDGNEREPSVLPARFPNLLAN 170
Cdd:PRK09631 79 LAnKDL-----FIDKQGNFGNLfTGDPASAARYIECRLTPLAKEVL--YNKEITEYEPSYDGRNNEPLCLPAKIPVILIQ 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 171 GASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAelmediegPDFPTAGLIlgksgIRRAYETGRGSIQMRSRavIE 250
Cdd:PRK09631 152 GAEGIAVGMATKILPHNFNEILQAVKSELLGESFALY--------PDFPTGGIV-----DVSEYADGNGKVLVRAK--IE 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 251 ERggGRQRIVVTEIPFQVNKARMIEKIAELVRDK--KIDGITDLRDETslrtgVRVVIDVRKDANASVILNNLYKQTPLQ 328
Cdd:PRK09631 217 TK--DEKTIVIREIPFGTTTESLIASIEKAARKGkiKISSINDYTAEN-----VEIEIKLPRGVYASEVIEALYAYTDCE 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 329 TSFGVNMIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDR--AHILEglRIALDH-IDEIISTIRESDTDK 405
Cdd:PRK09631 290 VSISVNLLVIKDRYPVIYTVTDIIKFHAEHLQKVLKMELELERAKLLEKifAKTLE--QIFIEErIYKRIETISSEEDVI 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 406 VAMESLQQRFK------LSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILAD-EEVLLQLVRDELTEIRD 478
Cdd:PRK09631 368 SIVLSELKPFKeelsrdVTEEDIENLLKIPIRRISLFDIDKNQKEIRILNKELKSVEKNLKSiKGYAINFIDKLLAKYSK 447
|
490
....*....|..
gi 616687109 479 RFgdDRRTEIQL 490
Cdd:PRK09631 448 EY--PRKTEISL 457
|
|
| PRK12758 |
PRK12758 |
DNA gyrase/topoisomerase IV subunit A; |
22-497 |
1.59e-65 |
|
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain] Cd Length: 869 Bit Score: 236.05 E-value: 1.59e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 22 FLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEqgmTPDKSYKKSARIVGDVMgKYHPHGDSSIYEAMVRMAQdfsyRY 101
Cdd:PRK12758 31 FLDYASYVILERAVPHIEDGLKPVQRRILHSMKE---MDDGRYNKVANVVGHTM-QYHPHGDASIGDALVQLGQ----KD 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 102 PLVDGQGNFGS-MDGDGAAAMRYTEARMTKITLELLrdINKDTIDFIDNYDGNEREPSVLPARFPNLLANGASGIAVGMA 180
Cdd:PRK12758 103 LLIDTQGNWGNiLTGDGAAAPRYIEARLSKFALEVV--FNPKTTEWQLSYDGRKKEPVTLPVKFPLLLAQGAEGIAVGLS 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 181 TNIPPHNLTELINGVLSLSKNPDISIAelmediegPDFPTAGLIlgksgIRRAYETGRGSIQMRSRAVIEERggGRQRIV 260
Cdd:PRK12758 181 TKILPHNFNELIDASIAYLKGKEFKLY--------PDFPTGGII-----DVSNYNDGERGGRVRVRAKIEKL--DKKTLV 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 261 VTEIPFQVNKARMIEKIAELVRDKKIDgITDLRDETSlrTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMIALVN 340
Cdd:PRK12758 246 ITEIPYGTTTSSLIDSILKANDKGKIK-IKKVEDNTA--ADVEILVHLAPGVSPDKTIDALYAFTDCEVSISPNACVIID 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 341 GRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDhiDEIISTIRESDTDKVAMESLQQRFK---- 416
Cdd:PRK12758 323 NKPHFLGVSDILRRSTDHTVSLLKQELEIRLSELEEQWHFASLEKIFIE--ERIYKEIEEAETWEAVIEAIDKGLEpfkk 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 417 -----LSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELEAILADeevLLQLVRDELTEIRDRFGDD--RRTEIQ 489
Cdd:PRK12758 401 qfireVTEDDIVRLTEIKIKRISKFDSDKADELIARLEAEIAEVKHHLAH---LTDYAIAYFTNLKKKYGKGreRKTEIR 477
|
....*...
gi 616687109 490 LggFEDLE 497
Cdd:PRK12758 478 N--FDTIE 483
|
|
| PRK09630 |
PRK09630 |
DNA topoisomerase IV subunit A; Provisional |
12-352 |
4.57e-50 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022 Cd Length: 479 Bit Score: 183.94 E-value: 4.57e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 12 RNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNeqgMTPDKSYKKSARIVGDVMGkYHPHGDSSIYEAMV 91
Cdd:PRK09630 2 SDVSDLFKTHFMHYASYVILERAIPHILDGLKPVQRRLLWTLF---RMDDGKMHKVANIAGRTMA-LHPHGDAPIVEALV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 92 RMAQdfsyRYPLVDGQGNFGS-MDGDGAAAMRYTEARMTKITLELLrdINKDTIDFIDNYDGNEREPSVLPARFPNLLAN 170
Cdd:PRK09630 78 VLAN----KGYLIDTQGNFGNpLTGDPHAAARYIEARLSPLAKEVL--FNTDLMTFHDSYDGREKEPDILPAKLPLLLLH 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 171 GASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAelmediegPDFPTAGLILGKSgirraYETGRGSIQMRSRAVIE 250
Cdd:PRK09630 152 GVDGIAVGMTTKIFPHNFCELLEAQIAILNDQPFTLL--------PDFPSGGTMDASE-----YQDGLGSITLRASIDII 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 251 ErgggRQRIVVTEIPFQVNKARMIEKIAELVRDK--KIDGITDLRDETSlrtgvRVVIDVRKDANASVILNNLYKQTPLQ 328
Cdd:PRK09630 219 N----DKTLLIKEICPSTTTETLIRSIENAAKRGiiKIDSIQDFSTDLP-----HIEIKLPKGIYAKDLLRPLFTHTECQ 289
|
330 340
....*....|....*....|....
gi 616687109 329 TSFGVNMIALVNGRPKLINLKEAL 352
Cdd:PRK09630 290 VILTSRPTAIYQNKPVETSISEIL 313
|
|
| 52 |
PHA02592 |
DNA topisomerase II medium subunit; Provisional |
9-456 |
1.07e-45 |
|
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain] Cd Length: 439 Bit Score: 170.24 E-value: 1.07e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 9 INERNITSEMRESFLDYAMSVIVARALPDVRDGLKPVHRRILYGLNEQGMTPDKSYKKSARIVGDV-MGKYHpHGDSSIY 87
Cdd:PHA02592 3 LKERSLKSIVNNEALEYAMYTVEERAIPNLIDGLKPVQRFVIHRALEYAKGNKEKFDKVAAIAGGVaDLGYH-HGETSAQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 88 EAMVRMAQDFSYRYPLVDGQGNFGSMDGDGAAAMRYTEARMTkitlELLRDINKDTidfidNYDGNEREPSVLPARF--- 164
Cdd:PHA02592 82 DAGALMANTWNNNIPLLDGQGNFGSRLVQKAAAARYIFARVH----DNFRKIYKDE-----DLAPVHEDPEHIPPAFylp 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 165 --PNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISiaELmeDIEGPDFptaglilgksgirrayetgRGSIQ 242
Cdd:PHA02592 153 iiPMVLLNGVSGIATGYATNILPHSPKSVIKAVLAALNGKDIT--EP--KVQFPEF-------------------KGEVV 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 243 MRSRAVIEERG----GGRQRIVVTEIPFQVNKARMIEKIAELVRDKKIDGITDLRDEtslrtGVRVVIDVRKDANASVIL 318
Cdd:PHA02592 210 EIEPGSYEIRGtyelNGKTKLHITEIPVKYDRETYVAVLDPLEEKGKIVSYDDCTED-----GFRFKVTLKREENEEATH 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 319 NNLYKQTPLQTSFGVNmIALVNGRPKLI---NLKEALVHYLEHQKTVVRRRTQYNLRKAKDRahilegLRIALDH---ID 392
Cdd:PHA02592 285 EKIMKDFGLIERVSQN-ITVINENGKLKvyeNAEDLIRDFVEIRKTYVQKRIQYEIKETEEA------FDLALAKaefIK 357
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 616687109 393 EIISTIRESD--TDKVAMESLQQrFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLNYISELE 456
Cdd:PHA02592 358 RVIAGEIVLQgkTRSELTEELSD-NKDFGEYADKLVAMNIYSMTSDEREKLQKEAEELEKEHEYWK 422
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
32-487 |
1.33e-20 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 98.19 E-value: 1.33e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 32 ARALPDVRDGLKPVHRRILYGLNEQGMtpdKSYKKSARIVGDVMGK--YHpHGDSSIYEAMVRMAQDF--SYRYPLVDGQ 107
Cdd:PTZ00108 679 ERSIPSLVDGLKPGQRKILFACFKRNL---KNEIKVAQLSGYVSEHsaYH-HGEQSLQQTIVGMAQNFvgSNNINLLYPC 754
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 108 GNFGS--MDGDGAAAMRYTEARMTKITlellRDINKDTIDFIDNY---DGNEREPSVLPARFPNLLANGASGIAVGMATN 182
Cdd:PTZ00108 755 GQFGSrlQGGKDHAAARYIFTKLSKIT----RYIFPEEDDPILDYledDGQSVEPFYYVPIIPMVLVNGAEGIGTGFSTS 830
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 183 IPPHNLTELINGVLSLsknpdisiaelmedIEGPDFPTaglilgksgIRRAYETGRGSIQM------RSRAVIEERGGGr 256
Cdd:PTZ00108 831 IPNYNPLDIIDNLRRR--------------LNGEEVRP---------LVPWYRGFKGTIERnpkgkfISKGIYEKVPDG- 886
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 257 qRIVVTEIPFQVNKARMIEKIAELVRDKKiDGITDLRDETslrTGVRVVIDVR------KDANASVILNNLYKQTPLQTS 330
Cdd:PTZ00108 887 -TVEITELPIGKWTEDYKEFLESETLKEK-DVIVDYRDYS---TANTVHFTVKlndgvlEQWEEEGIEKVFKLKSTISTT 961
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 331 fgvNMIAL-VNGR-PKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHI------------DEIIS 396
Cdd:PTZ00108 962 ---NMVLFdENGKiKKYSDALDILKEFYLVRLDLYKKRKEYLLGKLERELARLSNKVRFIKHVingelvitnakkKDLVK 1038
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 397 TIRE------SDTDKVAMESLQQRFKLSEKQAQA------------------ILDMRLRRLTgLER-DKIEAEYNELLNy 451
Cdd:PTZ00108 1039 ELKKlgyvrfKDIIKKKSEKITAEEEEGAEEDDEaddeddeeelgaavsydyLLSMPIWSLT-KEKvEKLNAELEKKEK- 1116
|
490 500 510
....*....|....*....|....*....|....*.
gi 616687109 452 isELEAILADEEVllQLVRDELTEIRDRFGDDRRTE 487
Cdd:PTZ00108 1117 --ELEKLKNTTPK--DMWLEDLDKFEEALEEQEEVE 1148
|
|
| PLN03128 |
PLN03128 |
DNA topoisomerase 2; Provisional |
32-383 |
7.05e-19 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain] Cd Length: 1135 Bit Score: 92.46 E-value: 7.05e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 32 ARALPDVRDGLKPVHRRILYGLNEQGMtpdKSYKKSARIVGDVM--GKYHpHGDSSIYEAMVRMAQDF--SYRYPLVDGQ 107
Cdd:PLN03128 672 ARSIPSMVDGLKPSQRKVLFACFKRNL---KSEIKVAQLSGYVAehSAYH-HGEASLASTIIGMAQDFvgSNNINLLTPS 747
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 108 GNFGS--MDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNyDGNEREPSVLPARFPNLLANGASGIAVGMATNIPP 185
Cdd:PLN03128 748 GQFGTrlQGGKDAASARYIFTRLSPITRALFPKDDDVLLNYLNE-DGQSIEPEWYCPIIPMVLVNGSEGIGTGWSTFIPN 826
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 186 HNLTELINGVLSLsknpdisiaelmedIEGPDFPT-----AGLilgKSGIRRAYETGRGSIQMRSR-AVIEERgggrqRI 259
Cdd:PLN03128 827 YNPRDIIANIRRL--------------LRGEELEPmhpwyRGF---KGTITEVSTSRSGSYTVTGIiEQIGDT-----TI 884
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 260 VVTEIPFQV---NKARMIEKIAELVRDKKIDgITDLRdETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVNMI 336
Cdd:PLN03128 885 RITELPVRKwtqDYKEFLEALLTGTKKKEPE-IKDFK-ENHTDTTVHFTVTLSEEKMARALAEGLEKKFKLSTTISTSNM 962
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 616687109 337 ALVNGRPKL------INLKEALVH----YLEHQKTVVRRRTQYNLRKAKDRAHILEG 383
Cdd:PLN03128 963 HLFDKDGKIkkydspEDILEEFFHlrldLYVKRKEVLLENLEYELKKLDNKARFILA 1019
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
33-195 |
3.29e-14 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 77.21 E-value: 3.29e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 33 RALPDVRDGLKPVHRRILYGLNEQGMtpdKSYKKSARIVGDV--MGKYHpHGDSSIYEAMVRMAQDF--SYRYPLVDGQG 108
Cdd:PLN03237 698 RSIPSMVDGLKPGQRKILFCSFKRNF---VKEAKVAQLSGYVseHSAYH-HGEQSLASTIIGMAQDFvgSNNINLLLPNG 773
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616687109 109 NFG--SMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNyDGNEREPSVLPARFPNLLANGASGIAVGMATNIPPH 186
Cdd:PLN03237 774 QFGtrLQGGKDHASARYIFTRLSPITRFLFPKDDDILLDYLNE-DGQSIEPTWYMPIIPTVLVNGAEGIGTGWSTFIPNY 852
|
....*....
gi 616687109 187 NLTELINGV 195
Cdd:PLN03237 853 NPRDIVANI 861
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
661-706 |
4.72e-10 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 55.57 E-value: 4.72e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 616687109 661 EDILIGTSHASLIRFPESTLRPLGRTATGVKGITLREGDEVVGLDV 706
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLV 46
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
506-553 |
3.61e-09 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 53.26 E-value: 3.61e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 616687109 506 QIVITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLS 553
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
556-606 |
8.14e-09 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 52.10 E-value: 8.14e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 616687109 556 DHVLFFTNKGRVYKLKGYEVPELSRQSKGIPVVNaieLENDEVISTMIAVK 606
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGIN---LKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
713-750 |
8.72e-09 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 52.10 E-value: 8.72e-09
10 20 30
....*....|....*....|....*....|....*...
gi 616687109 713 DEVLVVTENGYGKRTPVNDYRLSNRGGKGIKTATITER 750
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEG 38
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
764-811 |
9.71e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 49.02 E-value: 9.71e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 616687109 764 EDLMIVTNVGVIIRLDVADISQNGRAAQGVRLIRLGDDQFVSTVAKVK 811
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
613-658 |
3.03e-07 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 47.48 E-value: 3.03e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 616687109 613 NFLVFATKRGVVKRSALSNFSRINRN--GKIAISFREDDELIAVRLTS 658
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGakGVKGINLKEGDKVVSVLVVN 48
|
|
| |
