|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
42-669 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 569.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 42 AFFVVLLLGILLFAYYAWKAPAFTE-AKLQDPIPAKIYDKNGELVKTLdNGQRHEHVNLKDVPKSMKDAVLATEDNRFYE 120
Cdd:COG0744 22 LAVLVLAALAGLVALYVADLPDPEElEDLALPQTSTIYDRDGTLIATL-GDENREWVPLDQIPPHLKDAVVAIEDRRFYE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 121 HGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLSQHKSIGRKAQEAYLSYRLEQEYSKDDIFQVYLNKIYYSDG 200
Cdd:COG0744 101 HGGVDPKGIARALVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRG 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 201 VTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIYDHPKAAEDRKNTVLYLMHYHKRITDKQWEEAKKIDLKanl 280
Cdd:COG0744 181 AYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLT--- 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 281 VNRTAEERqnidtnQDSEYNSYVNFVKSELMNNkaFKDENLgnvLQSGIKIYTNMDKDVQKTLQNDVDNG-SFYKNKDQQ 359
Cdd:COG0744 258 LVPPPNGA------AAGKYPYFVDYVRRELEEL--LGEDDL---YRGGLKIYTTLDPKLQKAAEKAVKNVlPEGKPGGLQ 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 360 VGATILDSKTGGLVAISGGRDFKDvVNRNQATD-PHPTGSSLKPFlAYGPAIENmKWATNHAIQDES-SYQVDGSTFRNY 437
Cdd:COG0744 327 AALVVVDPKTGEVLAMVGGRDYGK-SQFNRATQaKRQPGSTFKPF-VYAAALEQ-GYTPATTVDDEPvTFPGGGWSPKNY 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 438 DVKSHGTVSIYDALRQSFNIPALKAWQSVkqnaGNDAPKKFAAKLGLNYEGEIGPSEVLGgsASEFSPTQLASAFAAIAN 517
Cdd:COG0744 404 DGRYRGPVTLREALANSLNTPAVRLAQEV----GLDKVVDTARRLGITSPLDPNPSLALG--TSEVSPLEMASAYATFAN 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 518 GGTYNNAHSIQKVVTRDGETI-EYDHTSHKAMSDYTAYMLAEMLKGTFKpYGSAYGHGVSGVNMGAKTGTgTygaetysq 596
Cdd:COG0744 478 GGVYVEPHAITKVTDADGKVLyEAKPKCEQVISPEVAYLMTDMLQDVVT-SGTGRAARLPGRPVAGKTGT-T-------- 547
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 616541826 597 ynlpdNAAKDVWINGFTPQYTMSVWMGFSkvkQYGENSFVGHSQqeYPQFLYENVMSKISS-RDGEDFKRPSSV 669
Cdd:COG0744 548 -----NDNRDAWFVGYTPQLVTAVWVGND---DNSPMGYVTGGS--LPAPIWRDFMEAALEgLPVEDFPKPSGV 611
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
93-631 |
3.52e-152 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 452.87 E-value: 3.52e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 93 RHEHVNLKDVPKSMKDAVLATEDNRFYEHGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLSQHKSIGRKAQEA 172
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 173 YLSYRLEQEYSKDDIFQVYLNKIYYSDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIYDHPKAAEDRKNT 252
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 253 VLYLMHYHKRITDKQWEEAKKIDLKANLVNRTAEErqnidtnqdSEYNSYVNFVKSELmnnkafkDENLGNVL-QSGIKI 331
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYLQTKKSEQ---------YKAPYFVDYVIQEL-------EEEYGEELyTGGLKI 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 332 YTNMDKDVQKTLQNDVDNGSFYK----NKDQQVGATILDSKTGGLVAISGGRDFKDvVNRNQAT----DPhptGSSLKPF 403
Cdd:TIGR02074 225 YTTLDLDAQKAAEKVLNTGLRVAgrrdGDDLQAALVAIDPDTGAVRALVGGRDYGK-SQFNRATqakrQP---GSTFKPF 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 404 LaYGPAIENmKWATNHAIQDEsSYQVDGSTF---RNYDVKSHGTVSIYDALRQSFNIPALKAWQSVkqnaGNDAPKKFAA 480
Cdd:TIGR02074 301 V-YAAALEK-GLTPATIVNDE-PITYNGNGPwspKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEV----GLDKVVALAK 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 481 KLGLNYEGEIGPSEVLGGsaSEFSPTQLASAFAAIANGGTYNNAHSIQKVVTRDGETIeYDHTSH--KAMSDYTAYMLAE 558
Cdd:TIGR02074 374 RFGITSPLDPVLSLALGT--VEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVI-YENKPKttQVISPATAYIMTD 450
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 616541826 559 MLKGTFKpYGSAYGHGVSGVNMGAKTGTgtygaetySQYNlpdnaaKDVWINGFTPQYTMSVWMGFSKVKQYG 631
Cdd:TIGR02074 451 MLKGVVE-SGTGRSARLPGRPVAGKTGT--------TQNW------RDAWFVGYTPYYVTAVWVGYDDKKTLG 508
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
81-258 |
1.35e-82 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 259.76 E-value: 1.35e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 81 NGELVKTLDnGQRHEHVNLKDVPKSMKDAVLATEDNRFYEHGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLS 160
Cdd:pfam00912 1 DGTLLAELG-EENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 161 QHKSIGRKAQEAYLSYRLEQEYSKDDIFQVYLNKIYYSDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIY 240
Cdd:pfam00912 80 PERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPL 159
|
170
....*....|....*...
gi 616541826 241 DHPKAAEDRKNTVLYLMH 258
Cdd:pfam00912 160 RNPERAKRRRNLVLDRMV 177
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
90-623 |
1.00e-49 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 187.28 E-value: 1.00e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 90 NGQRHEHVNLKDVPKSMKDAVLATEDNRFYEHGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLSQHKSIGRKA 169
Cdd:PRK09506 207 NGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 170 QEAYLSYRLEQEYSKDDIFQVYLNKIYY----SDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIYDHPKA 245
Cdd:PRK09506 287 NEAYMALIMDARYSKDRILELYLNEVYLgqsgDDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKL 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 246 AEDRKNTVLYLMHyHKRITDKqweeakkiDLKANLVNRT--AEERQNIDTNQDseynSYVNFVKSELMNNKAFKDENLgn 323
Cdd:PRK09506 367 ALERRNLVLRLLQ-QQQIIDQ--------ELYDMLSARPlgVQPKGGVISPQP----AFMQMVRQELQAKLGDKVKDL-- 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 324 vlqSGIKIYTNMDKDVQKTLQNDVDNG-----SFYKNKDQQVGATILDSKTGGLVAISGGRDfKDVVNRNQATDP-HPTG 397
Cdd:PRK09506 432 ---SGVKIFTTLDPVSQDAAEKAVEEGipalkKQRKLSDLETAMVVVDRFSGEVRAMVGGSE-PQFAGYNRAMQArRSIG 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 398 SSLKPFLAYGPAIENMKWATNHAIQDE--SSYQVDGSTF--RNYDVKSHGTVSIYDALRQSFNIPALKAWQSVkqnaGND 473
Cdd:PRK09506 508 SLAKPATYLTALSQPDKYRLNTWIADApiSLRQPNGQVWspQNDDRRFSGRVMLVDALTRSMNVPTVNLGMAL----GLP 583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 474 APKKFAAKLGLNyEGEIG--PSEVLGgsASEFSPTQLASAFAAIANGGTYNNAHSIQKVVTRDGeTIEYDH--TSHKAMS 549
Cdd:PRK09506 584 AVTDTWIKLGVP-KDQLNpvPAMLLG--ALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDG-KVLYQSfpQAERAVP 659
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 616541826 550 DYTAYM-LAEMLKGTFKPYGSAYGHGVSGVNMGAKTGTgtygaetysqynlpDNAAKDVWINGFTPQYTMSVWMG 623
Cdd:PRK09506 660 AQAAYLtLYTMQQVVQRGTGRQLGAKYPNLHLAGKTGT--------------TNDLVDSWFAGIDGKEVTITWVG 720
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
42-669 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 569.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 42 AFFVVLLLGILLFAYYAWKAPAFTE-AKLQDPIPAKIYDKNGELVKTLdNGQRHEHVNLKDVPKSMKDAVLATEDNRFYE 120
Cdd:COG0744 22 LAVLVLAALAGLVALYVADLPDPEElEDLALPQTSTIYDRDGTLIATL-GDENREWVPLDQIPPHLKDAVVAIEDRRFYE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 121 HGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLSQHKSIGRKAQEAYLSYRLEQEYSKDDIFQVYLNKIYYSDG 200
Cdd:COG0744 101 HGGVDPKGIARALVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRG 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 201 VTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIYDHPKAAEDRKNTVLYLMHYHKRITDKQWEEAKKIDLKanl 280
Cdd:COG0744 181 AYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLT--- 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 281 VNRTAEERqnidtnQDSEYNSYVNFVKSELMNNkaFKDENLgnvLQSGIKIYTNMDKDVQKTLQNDVDNG-SFYKNKDQQ 359
Cdd:COG0744 258 LVPPPNGA------AAGKYPYFVDYVRRELEEL--LGEDDL---YRGGLKIYTTLDPKLQKAAEKAVKNVlPEGKPGGLQ 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 360 VGATILDSKTGGLVAISGGRDFKDvVNRNQATD-PHPTGSSLKPFlAYGPAIENmKWATNHAIQDES-SYQVDGSTFRNY 437
Cdd:COG0744 327 AALVVVDPKTGEVLAMVGGRDYGK-SQFNRATQaKRQPGSTFKPF-VYAAALEQ-GYTPATTVDDEPvTFPGGGWSPKNY 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 438 DVKSHGTVSIYDALRQSFNIPALKAWQSVkqnaGNDAPKKFAAKLGLNYEGEIGPSEVLGgsASEFSPTQLASAFAAIAN 517
Cdd:COG0744 404 DGRYRGPVTLREALANSLNTPAVRLAQEV----GLDKVVDTARRLGITSPLDPNPSLALG--TSEVSPLEMASAYATFAN 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 518 GGTYNNAHSIQKVVTRDGETI-EYDHTSHKAMSDYTAYMLAEMLKGTFKpYGSAYGHGVSGVNMGAKTGTgTygaetysq 596
Cdd:COG0744 478 GGVYVEPHAITKVTDADGKVLyEAKPKCEQVISPEVAYLMTDMLQDVVT-SGTGRAARLPGRPVAGKTGT-T-------- 547
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 616541826 597 ynlpdNAAKDVWINGFTPQYTMSVWMGFSkvkQYGENSFVGHSQqeYPQFLYENVMSKISS-RDGEDFKRPSSV 669
Cdd:COG0744 548 -----NDNRDAWFVGYTPQLVTAVWVGND---DNSPMGYVTGGS--LPAPIWRDFMEAALEgLPVEDFPKPSGV 611
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
93-631 |
3.52e-152 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 452.87 E-value: 3.52e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 93 RHEHVNLKDVPKSMKDAVLATEDNRFYEHGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLSQHKSIGRKAQEA 172
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 173 YLSYRLEQEYSKDDIFQVYLNKIYYSDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIYDHPKAAEDRKNT 252
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 253 VLYLMHYHKRITDKQWEEAKKIDLKANLVNRTAEErqnidtnqdSEYNSYVNFVKSELmnnkafkDENLGNVL-QSGIKI 331
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYLQTKKSEQ---------YKAPYFVDYVIQEL-------EEEYGEELyTGGLKI 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 332 YTNMDKDVQKTLQNDVDNGSFYK----NKDQQVGATILDSKTGGLVAISGGRDFKDvVNRNQAT----DPhptGSSLKPF 403
Cdd:TIGR02074 225 YTTLDLDAQKAAEKVLNTGLRVAgrrdGDDLQAALVAIDPDTGAVRALVGGRDYGK-SQFNRATqakrQP---GSTFKPF 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 404 LaYGPAIENmKWATNHAIQDEsSYQVDGSTF---RNYDVKSHGTVSIYDALRQSFNIPALKAWQSVkqnaGNDAPKKFAA 480
Cdd:TIGR02074 301 V-YAAALEK-GLTPATIVNDE-PITYNGNGPwspKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEV----GLDKVVALAK 373
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 481 KLGLNYEGEIGPSEVLGGsaSEFSPTQLASAFAAIANGGTYNNAHSIQKVVTRDGETIeYDHTSH--KAMSDYTAYMLAE 558
Cdd:TIGR02074 374 RFGITSPLDPVLSLALGT--VEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVI-YENKPKttQVISPATAYIMTD 450
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 616541826 559 MLKGTFKpYGSAYGHGVSGVNMGAKTGTgtygaetySQYNlpdnaaKDVWINGFTPQYTMSVWMGFSKVKQYG 631
Cdd:TIGR02074 451 MLKGVVE-SGTGRSARLPGRPVAGKTGT--------TQNW------RDAWFVGYTPYYVTAVWVGYDDKKTLG 508
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
42-624 |
2.58e-120 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 378.73 E-value: 2.58e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 42 AFFVVLLLGILLFAYYAWKA----PAFTEakLQD---PIPAKIYDKNGELVktldnG----QRHEHVNLKDVPKSMKDAV 110
Cdd:COG5009 10 LLLLLLLLGALAVAGLYLYLspdlPDVET--LKDyqpPTPSRVYSADGKLI-----AefgeERRIPVPIEEIPPLLINAF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 111 LATEDNRFYEHGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLSQHKSIGRKAQEAYLSYRLEQEYSKDDIFQV 190
Cdd:COG5009 83 LAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSKDEILEL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 191 YLNKIYYSDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIYDHPKAAEDRKNTVLYLMHYHKRITDKQWEE 270
Cdd:COG5009 163 YLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYITQAEYEA 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 271 AKKIDLKANLVNRTAEErqnidtnqDSEYnsYVNFVKSELMNNkaFKDENLgnvLQSGIKIYTNMDKDVQKTLQ------ 344
Cdd:COG5009 243 AKAEPLTARYHGASAEV--------DAPY--FAEMVRRELVER--YGEDAL---YTGGLKVYTTLDPRLQEAAEkalrdg 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 345 --------------------------------------------------------------------------NDVDNG 350
Cdd:COG5009 308 llaydrrhgyrgpeahldlaeedwdealaevpdvgdlrpavvlevddksarvglrdgetgtlpleglkwarpyiNDNRRG 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 351 SFYKNKDQ---------------------QV----GATI-LDSKTGGLVAISGGRDF-KDVVNRnqATD----PhptGSS 399
Cdd:COG5009 388 PAPKSASDvlkpgdvirvrpvadggwrlrQIpevqGALVaLDPHTGAVLALVGGFDFeQSKFNR--ATQakrqP---GSS 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 400 LKPFLaYGPAIEN-MKWAT--N---HAIQDESSYQVdgSTFRNYDVKSHGTVSIYDALRQSFNIPALKAWQSVkqnaGND 473
Cdd:COG5009 463 FKPFV-YAAALDNgYTPATiiNdapIVFDDGGGGGV--WRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDV----GID 535
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 474 APKKFAAKLGLNyeGEIGPSE--VLGgsASEFSPTQLASAFAAIANGGTYNNAHSIQKVVTRDGETIeYDHTSHKA---- 547
Cdd:COG5009 536 YVIDYAERFGIY--SKLPPNLslALG--SGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVI-YRADPARAcedc 610
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 548 -------------------MSDYTAYMLAEMLKGTFKpYGSAYGHGVSGVNMGAKTGTgTygaetysqynlpdNAAKDVW 608
Cdd:COG5009 611 daaewdgaeprlpdpaeqvIDPRTAYQMTSMLRGVVQ-RGTGRRARALGRDIAGKTGT-T-------------NDSKDAW 675
|
730
....*....|....*.
gi 616541826 609 INGFTPQYTMSVWMGF 624
Cdd:COG5009 676 FVGFTPDLVAGVWVGF 691
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
81-258 |
1.35e-82 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 259.76 E-value: 1.35e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 81 NGELVKTLDnGQRHEHVNLKDVPKSMKDAVLATEDNRFYEHGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLS 160
Cdd:pfam00912 1 DGTLLAELG-EENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 161 QHKSIGRKAQEAYLSYRLEQEYSKDDIFQVYLNKIYYSDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIY 240
Cdd:pfam00912 80 PERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPL 159
|
170
....*....|....*...
gi 616541826 241 DHPKAAEDRKNTVLYLMH 258
Cdd:pfam00912 160 RNPERAKRRRNLVLDRMV 177
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
89-623 |
4.19e-74 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 254.26 E-value: 4.19e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 89 DNGQRHEHVNLKDVPKSMKDAVLATEDNRFYEHGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLSQHKSIGRK 168
Cdd:TIGR02071 142 PNGEQRLFVPRDQFPELLVDTLLATEDRDFYEHDGISLYSIGRAVWVNLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRK 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 169 AQEAYLSYRLEQEYSKDDIFQVYLNKIYY----SDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIYDHPK 244
Cdd:TIGR02071 222 ANEAYMALILDARYSKDRILELYLNEVYLgqsgDDAIHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNPWRNPD 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 245 AAEDRKNTVLYLMHYHKRITDKQWEEAKKIDLKanlVNRTAeerqnidtNQDSEYNSYVNFVKSELMNNKAFKDENLgnv 324
Cdd:TIGR02071 302 RALERRNLVLRLLQEQKIIDDEEYDMLSARPLG---VQKKG--------GIISRQPAFLQLVRRELRQKLGDKVKDL--- 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 325 lqSGIKIYTNMDKDVQKTLQNDVDNG-----SFYKNKDQQVGATILDSKTGGLVAISGGRDfKDVVNRNQATDP-HPTGS 398
Cdd:TIGR02071 368 --SGLRIFTTLDPVSQSAAEQAVQETipalkKKKKLPDLEAAMVVTDRFTGEVRAMVGGSD-PQFAGFNRALQArRQIGS 444
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 399 SLKPFLaYGPAIEN-MKWATNHAIQDE--SSYQVDGS--TFRNYDVKSHGTVSIYDALRQSFNIPALKawqsVKQNAGND 473
Cdd:TIGR02071 445 LVKPAV-YLTALSQpDKYRLNTWIEDQplSIKLSNGQvwSPQNYDRRYSGTVMLYDALAHSLNIPTVN----LGMKVGLP 519
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 474 APKKFAAKLGLNyEGEIG--PSEVLGgsASEFSPTQLASAFAAIANGGTYNNAHSIQKVVTRDGETI-EYDHTSHKAMSD 550
Cdd:TIGR02071 520 KVSQTWNKLGIN-KDEIPpvPSMLLG--AINLTPYEVAQLYQTIASGGNRAPLSAVRSVLDEDGKVLyQSDPQAEQAVPS 596
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 616541826 551 YTAY-----MLAEMLKGTFKPYGSAYGHgvsgVNMGAKTGTgtygaetysqynlpDNAAKDVWINGFTPQYTMSVWMG 623
Cdd:TIGR02071 597 QAAYltlyaMQQVVQRGTARSLGADFPS----LSLAGKTGT--------------TNDNRDSWFAGIDGKEVTIIWLG 656
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
42-623 |
5.61e-65 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 230.10 E-value: 5.61e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 42 AFFVVLLLGILLFAYYAWKAPAFteakLQDPIPAKIYDKNGEL--VKTLDNGQRHEHVNLKDVPKSMKDAVLATEDNRFY 119
Cdd:COG4953 15 LLALLLLALALWALDRLFPLPLL----FAVPYSTVVLDRDGTLlrAFLAADGQWRLPVPLDEVSPRYLQALLAYEDRRFY 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 120 EHGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKdafLS--QHKSIGRKAQEAYLSYRLEQEYSKDDIFQVYLNKIYY 197
Cdd:COG4953 91 YHPGVNPLALLRAAWQNLRSGRIVSGGSTLTMQVAR---LLepRPRTLSGKLRQILRALQLERRYSKDEILELYLNLAPY 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 198 SDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIYDHPKAAEDRKNTVLYLMHYHKRITDKQWEEAK--KID 275
Cdd:COG4953 168 GGNIEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRVLARLAEAGVIDAEEAALALlePVP 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 276 LK--------ANLVNRTAEERQNidtnqdseynsyvnfvkselmnnkafkdenlgnvlqsGIKIYTNMDKDVQKTLQNDV 347
Cdd:COG4953 248 ARrrplpqlaPHLARRLLRQLPG-------------------------------------GTRIRTTLDAGLQRRLERLV 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 348 DN--GSFYKNKDQQVGATILDSKTGGLVAISGGRDFKDV-----VNRNQAtdPHPTGSSLKPFLaYGPAIENMKWATNHA 420
Cdd:COG4953 291 RRyvRRLKQNGIHNAAVLVVDNRTGEVLAYVGSADFFDAsrqgqVDMVRA--LRSPGSTLKPFL-YGLALDQGLIHPETL 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 421 IQD-ESSYqvDGSTFRNYDVKSHGTVSIYDALRQSFNIPALKAWQSVKqnagndaPKKFAAKL------GLNYEGE-IGP 492
Cdd:COG4953 368 LADvPTSF--GGYRPENFDGTFQGPVSAREALARSLNIPAVRLLEALG-------PARFYARLrraglrLLLPPAEhYGL 438
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 493 SEVLGGsaSEFSPTQLASAFAAIANGGTYnnahsiQKVVTRDGETIEydhTSHKAMSDYTAYMLAEMLKGTFKPyGSAYG 572
Cdd:COG4953 439 SLILGG--AEVTLEELVGLYAALARGGEA------RPLRLLAGEPAS---PGRRLLSPGAAWLVRDILSDVPRP-DGAFG 506
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|...
gi 616541826 573 HGV--SGVNMGAKTGTgTYGaetYsqynlpdnaaKDVWINGFTPQYTMSVWMG 623
Cdd:COG4953 507 WRAldSPPPIAWKTGT-SYG---F----------RDAWAVGFTGRYTVGVWVG 545
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
90-623 |
1.00e-49 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 187.28 E-value: 1.00e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 90 NGQRHEHVNLKDVPKSMKDAVLATEDNRFYEHGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLSQHKSIGRKA 169
Cdd:PRK09506 207 NGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 170 QEAYLSYRLEQEYSKDDIFQVYLNKIYY----SDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIYDHPKA 245
Cdd:PRK09506 287 NEAYMALIMDARYSKDRILELYLNEVYLgqsgDDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKL 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 246 AEDRKNTVLYLMHyHKRITDKqweeakkiDLKANLVNRT--AEERQNIDTNQDseynSYVNFVKSELMNNKAFKDENLgn 323
Cdd:PRK09506 367 ALERRNLVLRLLQ-QQQIIDQ--------ELYDMLSARPlgVQPKGGVISPQP----AFMQMVRQELQAKLGDKVKDL-- 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 324 vlqSGIKIYTNMDKDVQKTLQNDVDNG-----SFYKNKDQQVGATILDSKTGGLVAISGGRDfKDVVNRNQATDP-HPTG 397
Cdd:PRK09506 432 ---SGVKIFTTLDPVSQDAAEKAVEEGipalkKQRKLSDLETAMVVVDRFSGEVRAMVGGSE-PQFAGYNRAMQArRSIG 507
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 398 SSLKPFLAYGPAIENMKWATNHAIQDE--SSYQVDGSTF--RNYDVKSHGTVSIYDALRQSFNIPALKAWQSVkqnaGND 473
Cdd:PRK09506 508 SLAKPATYLTALSQPDKYRLNTWIADApiSLRQPNGQVWspQNDDRRFSGRVMLVDALTRSMNVPTVNLGMAL----GLP 583
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 474 APKKFAAKLGLNyEGEIG--PSEVLGgsASEFSPTQLASAFAAIANGGTYNNAHSIQKVVTRDGeTIEYDH--TSHKAMS 549
Cdd:PRK09506 584 AVTDTWIKLGVP-KDQLNpvPAMLLG--ALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDG-KVLYQSfpQAERAVP 659
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 616541826 550 DYTAYM-LAEMLKGTFKPYGSAYGHGVSGVNMGAKTGTgtygaetysqynlpDNAAKDVWINGFTPQYTMSVWMG 623
Cdd:PRK09506 660 AQAAYLtLYTMQQVVQRGTGRQLGAKYPNLHLAGKTGT--------------TNDLVDSWFAGIDGKEVTITWVG 720
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
91-633 |
2.01e-49 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 185.82 E-value: 2.01e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 91 GQRHEHVNLKDVPKSMKDAVLATEDNRFYEHGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLSQHKSIGRKAQ 170
Cdd:PRK14850 154 GKKRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHTIQGGSTLTQQLVKNLFLTNTRSLWRKIN 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 171 EAYLSYRLEQEYSKDDIFQVYLNKIYY----SDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIYDHPKAA 246
Cdd:PRK14850 234 EIYMALILDRFYSKDRILELYLNEVYLgqdgNEQIRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNPNLT 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 247 EDRKNTVLYLMHYHKRITDKQWEEAKKIDLkanlvnrTAEERQNIdtnqDSEYNSYVNFVKSELMNNKAFKDENLgnvlq 326
Cdd:PRK14850 314 LKRRNLVLFLLYKQKVITRKLYKDLCSRPL-------NVQSKGNI----ISSHPAFIQLVCEEFHKKIHYPFKNF----- 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 327 SGIKIYTNMDKDVQKTLQNDVDNG-----SFYKNKDQQVGATILDSKTGGLVAISGGRDfKDVVNRNQATDP-HPTGSSL 400
Cdd:PRK14850 378 SGTKIFTTLDYISQNAAEQAVKIGipilkRKKRLKDLEVAMVIIDRFSGEVRALIGSSK-PEFNGYNRALKArRSIGSLS 456
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 401 KPFLAYGPAIENMKWATNHAIQDES-SYQVDGSTF---RNYDVKSHGTVSIYDALRQSFNIPALkawqSVKQNAGNDAPK 476
Cdd:PRK14850 457 KPITYLTALSQPEKYHLNTWISDTPiSIKLDNGQYwtpKNNNFSFSGKVMLIDALIHSINIPTV----HLSINLGLKKLV 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 477 KFAAKLGL--NYEGEIgPSEVLGgsASEFSPTQLASAFAAIANGGTYNNAHSIQKVVTRDGETI-EYDHTSHKAMSDYTA 553
Cdd:PRK14850 533 DSWILLGIssNYITPL-PSISLG--AINLTPMEVAQVFQIIGSGGYKSSLSSIRSIISDDNKVLyQNFPQSKHVESSQAS 609
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 554 Y-----MLAEMLKGTFKPYGSAYghgvSGVNMGAKTGTgtygaetysqynlpDNAAKDVWINGFTPQYTMSVWMGFS--- 625
Cdd:PRK14850 610 YltlyaMQQVVKSGTAKSLGTIF----KEFSLAGKTGT--------------TNNLVDSWFVGIDGKQVVITWIGRDnnh 671
|
....*...
gi 616541826 626 KVKQYGEN 633
Cdd:PRK14850 672 TTKLYGSS 679
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
42-349 |
2.94e-45 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 174.16 E-value: 2.94e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 42 AFFVVLLLGILLFAYYAWKAPAFTE-AKLQD---PIPAKIYDKNGELVKTLDNgQRHEHVNLKDVPKSMKDAVLATEDNR 117
Cdd:PRK11636 11 AVCCILLGAGSIYGLYRYIEPQLPDvATLKDvrlQTPMQVYSADGELIAQYGE-KRRIPLTLDQIPPEMVKAFIATEDSR 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 118 FYEHGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLSQHKSIGRKAQEAYLSYRLEQEYSKDDIFQVYLNKIYY 197
Cdd:PRK11636 90 FYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 198 SDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYN-IYDHPKAAEdRKNTVLYLMHYHKRITDKQWEEAKKIDL 276
Cdd:PRK11636 170 GYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTFNpLYSMDRAVA-RRNVVLSRMLDEGYITQAQYDQARSEPI 248
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 616541826 277 KANLvnrTAEErqnIDTNqdSEYNSyvNFVKSELMN---NKAFKDenlgnvlqsGIKIYTNMDKDVQKTLQNDVDN 349
Cdd:PRK11636 249 VANY---HAPE---IAFS--APYLS--EMVRQEMYNrygENAYED---------GYRVYTTITRKVQQAAQQAVRN 305
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
42-235 |
1.26e-31 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 122.96 E-value: 1.26e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 42 AFFVVLLLGIL-LFAYYAWKAPAFTEAKLQDPIPakiYDKNGELVKTLDngqrHEHVNLKDVPKSMKDAVLATEDNRFYE 120
Cdd:TIGR02070 9 AGVLLFNLAVFaALASWRFVPPPSTAFMVAEKLA---LWGQGDPTCGIQ----HRWRPYDQISPNLKRAVIASEDAKFVE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 121 HGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLSQHKSIGRKAQEAYLSYRLEQEYSKDDIFQVYLNKIYYSDG 200
Cdd:TIGR02070 82 HHGFDWEAIQDALEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSYLRKGLEAWATWMLETWWSKQRILEVYLNSVEWGNG 161
|
170 180 190
....*....|....*....|....*....|....*
gi 616541826 201 VTGIKAAAKYYFNKDLKDLNLAEEAYLAGLpqVPN 235
Cdd:TIGR02070 162 VFGAEAAARYYFKRSASNLTRGQAARLAAV--LPN 194
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
326-620 |
7.94e-29 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 121.85 E-value: 7.94e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 326 QSGIKIYTNMDKDVQKTLQNDVDNGsFYKNKDQQVGATILDSKTGGLVAISG--------GRDFKDVVNRNQA-TDPHPT 396
Cdd:COG0768 216 VPGKDLVLTIDSDLQKIAEEALKKA-VEEYKAKSGAVVVMDPKTGEILAMASypsfdpnlFVGGPDEPLRNRAvQGTYEP 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 397 GSSLKPFLAYGpAIENMKWATNHAIQDESSYQVDGSTFRNYDVKSHGTVSIYDALRQSFNIPALKawqsVKQNAGNDAPK 476
Cdd:COG0768 295 GSTFKPFTAAA-ALEEGVITPDTTFDCPGYYRVGGRTIRDWDRGGHGTLTLTEALAKSSNVGFYK----LALRLGIDKLY 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 477 KFAAKLGLNYEGEIG-PSEVLG--GSASEFSPT----------------QLASAFAAIANGGTYNNAHSIQKVVTRDGET 537
Cdd:COG0768 370 DYLKKFGLGQKTGIDlPGEASGllPSPKRWYPGetatmsigqglsvtplQLAQAYAAIANGGVLVKPHLVKEIVDPDGEV 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 538 IEY-DHTSHKAMSDYTAYMLAEMLKGTF-KPYGSAYGHGVSGVNMGAKTGT--------GTYGAETYSqynlpdnaakdV 607
Cdd:COG0768 450 VKEePEVLRRVISPETAETVREGMEGVVnEPGGTARRAAIPGYRVAGKTGTaqvvdignGGYYKGRHI-----------A 518
|
330
....*....|....*..
gi 616541826 608 WINGFT----PQYTMSV 620
Cdd:COG0768 519 SFVGFApadnPRYAVAV 535
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
92-271 |
1.68e-28 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 114.13 E-value: 1.68e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 92 QRHEHVNLKDVPKSMKDAVLATEDNRFYEHGALDYKRLFGAIGKNLTGGfGSEGASTLTQQVVKDAFLSQHKSIGRKAQE 171
Cdd:PRK13481 43 NKSSFVSADNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTISDR-DVQGGSTITQQVVKNYFYDNERSFTRKVKE 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 172 AYLSYRLEQEYSKDDIFQVYLNKIYYSDGVTGIKAAAKYYF-------NKDLKDLNLAEEAYLAGLPQVPNNYNIYDHPK 244
Cdd:PRK13481 122 LFVAHRVEKQYSKNEILSFYLNNIYFGDNQYTLEGAANHYFgttvnknSTTMSHITVLQSAILASKVNAPSVYNINDMSE 201
|
170 180
....*....|....*....|....*..
gi 616541826 245 AAEDRKNTVLYLMHYHKRITDKQWEEA 271
Cdd:PRK13481 202 NFTQRVSTNLEKMKQQNYINETQYQQA 228
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
97-623 |
1.89e-27 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 118.65 E-value: 1.89e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 97 VNLKDVPKSMKDAVLATEDNRFYEHGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKdaFLSQH-KSIGRKAQEAYLS 175
Cdd:PRK11240 65 VTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGSTLTMQVAR--LLDPHpRTFGGKIRQLWRA 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 176 YRLEQEYSKDDIFQVYLNKIYYSDGVTGIKAAAKYYFNKDLKDLNLAEEAYLAGLPQVPNNYNIYDHPKAAEDRKNTVLy 255
Cdd:PRK11240 143 LQLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNKVL- 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 256 lmhyhKRITDKQ-WEEAKkidlkanlVNRTAEERQNIDTNQDSEYNSYVnfvkSELMNNKAFKDenlgnvlqsgiKIYTN 334
Cdd:PRK11240 222 -----ERMAEQGvWSAEQ--------VKESREEPVWLAPRQMPQLAPLF----ARMMLGKSKSD-----------KIVTT 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 335 MDKDVQKTLQNDVDNGSFYKNKDQQVGATILDSKTGGLVAISGGRDFKD------VVNRNQATDPhptGSSLKPFLaYGP 408
Cdd:PRK11240 274 LDAGLQRRLEDLALNWKGRLPPRSSLAMIVVDHTDMAVRGWVGSVDLNDdsrfghVDMVNAIRSP---GSVLKPFV-YGL 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 409 AIEnmkwatNHAIQDESSYQ-VDGST--FR--NYDVKSHGTVSIYDALRQSFNIPA---LKAWqsvkqnagndAPKKFAA 480
Cdd:PRK11240 350 ALD------DGLIHPASLLQdVPRRTgdYRpgNFDSGFHGPVSMSEALVRSLNLPAvqvLEAY----------GPKRFAA 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 481 KL---GLNYE----GEIGPSEVLGGSASEFSptQLASAFAAIANGGtynNAHSI-----QKVVTRdgetieydhtshKAM 548
Cdd:PRK11240 414 KLrnvGLPLYlpagAEPNLSLILGGAGARLE--DMVAAYSAFARHG---KAAKLrlqpdDPLLER------------PLM 476
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 616541826 549 SDYTAYMLAEMLKGTFKPYGSAygHGVSGVNMGAKTGTgTYGaetYsqynlpdnaaKDVWINGFTPQYTMSVWMG 623
Cdd:PRK11240 477 SPGAAWIIRRIMADEAQPLPDA--ALPRVVPLAWKTGT-SYG---Y----------RDAWAIGVNARYVIGIWTG 535
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
361-620 |
1.07e-24 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 104.81 E-value: 1.07e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 361 GATILDSKTGGLVAISGGRDF----KDVVNRNQA-TDPHPTGSSLKPFLAyGPAIENMKWATNHAIQDESSYQVDGSTFR 435
Cdd:pfam00905 2 SAVVLDPKTGEVLAMVGKPSYdpngFIGPLRNRAvTSRYEPGSTFKPFTA-LAALDNGVLKPDETIFDWPGKQQGGKSIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 436 NYDVKSHGTVSIYDALRQSFNIPALKAWQSVKQNAGNDAPKKF--AAKLGLNYEGEIG---PSEVLGGSASEF------S 504
Cdd:pfam00905 81 DWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFgyGNKTGIGLPGENAgylTPYWLEGATASFgigltiT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 505 PTQLASAFAAIANGGTYNNAHSIQKVVTRDGETIEydhtsHK-AMSDYTAYMLAEMLKGTFKPYGSAYGHGVSGVNMGAK 583
Cdd:pfam00905 161 PLQQAQAYAAIANGGKLVPPHLVKSIEDKVDPKVL-----NKlPISKSTAEKVKDMLRLVVNDGTGTGTAAVPGYKVAGK 235
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 616541826 584 TGTGTYGAETYSQYNlpdNAAKDVWINGFT----PQYTMSV 620
Cdd:pfam00905 236 TGTAQVAGPKGGGYY---DGAQIGWFVGYApadnPKYAFAV 273
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
326-620 |
1.03e-13 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 74.48 E-value: 1.03e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 326 QSGIKIYTNMDKDVQKTLQNdvdngSFyknKDQQVGATILDSKTGGLVA---------------ISGgRDFKDVVN---- 386
Cdd:TIGR03423 223 VPGKDLVLTIDARLQQAAEK-----AL---GGRRGAVVVMDPRTGEILAmvstpsfdpnlfvdgISS-KDYKALLNdpdr 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 387 --RNQATDPH-PTGSSLKPFLAyGPAIENMKWATNHAIQDESSYQVDGSTFRNYDVKSHGTVSIYDALRQSFNIpalKAW 463
Cdd:TIGR03423 294 plLNRAIQGVyPPGSTFKPVVA-LAALEEGVITPETRIYCPGYFQLGGRRFRCWKRGGHGRVDLRKAIEESCDV---YFY 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 464 QsVKQNAGNDAPKKFAAKLGL-NYEGEIGPSEVLG---------------------GSAS------EFSPTQLASAFAAI 515
Cdd:TIGR03423 370 Q-LALRLGIDKIAEYAKRFGFgQKTGIDLPGEKSGlvpsrewkrkrfgqpwypgdtLNVSigqgyvLVTPLQLAVATAAL 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616541826 516 ANGGTYNNAHSIQKVVTRDGETIEYDHTSHKAM----SDYTAYMLAEMLKGTFKPYGSAYGHGV-SGVNMGAKTGT---- 586
Cdd:TIGR03423 449 ANGGKLYKPHLVKSIEDPDGGVVRRTEPEVLRPlpisPENLDVVREGMRDVVNGPGGTARRARLgLPYKMAGKTGTaqvv 528
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 616541826 587 -----GTYGAETYSqYNLPDNAakdvWINGFTP----QYTMSV 620
Cdd:TIGR03423 529 slkqgEKYDAEQIP-ERLRDHA----LFVAFAPydnpKIAVAV 566
|
|
| |
