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Conserved domains on  [gi|616418378|gb|KAC23561|]
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hypothetical protein W510_00243 [Staphylococcus aureus VET0215R]

Protein Classification

Rha family transcriptional regulator( domain architecture ID 11466542)

Rha family transcriptional regulator is a regulatory protein found in temperate phage and bacterial prophage regions

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
pRha COG3646
Phage regulatory protein Rha [Mobilome: prophages, transposons];
1-171 3.24e-35

Phage regulatory protein Rha [Mobilome: prophages, transposons];


:

Pssm-ID: 442863 [Multi-domain]  Cd Length: 211  Bit Score: 125.11  E-value: 3.24e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616418378   1 MQALQIV-EQNETHYVDSREVAEMIGKRHDNLVRDIKGYIKVLEdSSKLSSHNFfEESTYVNSQN-KVQPCYLLTKKGCD 78
Cdd:COG3646    1 MNQLELVtIKNGEPVTSSREIAELFGKRHKNVLRDIRKLISDLE-SPEFGQLNF-EESTYEDSQNgRERPEYLLTKDGFT 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616418378  79 IVANKMTGSKGILFTATYVDAFHKMDEYIKQQAQLnvPQTPMQALEMMFKAQKDQEQFNKQMQQEITGIRHIVGIETKNW 158
Cdd:COG3646   79 LLVMGFTGKKAAEFKAAYIDRFNEMEEQLKQQSAL--PQTLTEALRALAEQEEEKEAALLLGLALAAAAARALAEQSEAE 156

                        170
                 ....*....|...
gi 616418378 159 RNDTNKMLSAIAQ 171
Cdd:COG3646  157 QTGVKLLLALRAK 169
 
Name Accession Description Interval E-value
pRha COG3646
Phage regulatory protein Rha [Mobilome: prophages, transposons];
1-171 3.24e-35

Phage regulatory protein Rha [Mobilome: prophages, transposons];


Pssm-ID: 442863 [Multi-domain]  Cd Length: 211  Bit Score: 125.11  E-value: 3.24e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616418378   1 MQALQIV-EQNETHYVDSREVAEMIGKRHDNLVRDIKGYIKVLEdSSKLSSHNFfEESTYVNSQN-KVQPCYLLTKKGCD 78
Cdd:COG3646    1 MNQLELVtIKNGEPVTSSREIAELFGKRHKNVLRDIRKLISDLE-SPEFGQLNF-EESTYEDSQNgRERPEYLLTKDGFT 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616418378  79 IVANKMTGSKGILFTATYVDAFHKMDEYIKQQAQLnvPQTPMQALEMMFKAQKDQEQFNKQMQQEITGIRHIVGIETKNW 158
Cdd:COG3646   79 LLVMGFTGKKAAEFKAAYIDRFNEMEEQLKQQSAL--PQTLTEALRALAEQEEEKEAALLLGLALAAAAARALAEQSEAE 156

                        170
                 ....*....|...
gi 616418378 159 RNDTNKMLSAIAQ 171
Cdd:COG3646  157 QTGVKLLLALRAK 169
Phage_pRha pfam09669
Phage regulatory protein Rha (Phage_pRha); Members of this protein family are found in ...
 15-105 8.50e-33

Phage regulatory protein Rha (Phage_pRha); Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that Rha is a phage regulatory protein.


Pssm-ID: 462849 [Multi-domain]  Cd Length: 91  Bit Score: 115.01  E-value: 8.50e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616418378   15 VDSREVAEMIGKRHDNLVRDIKGYIKVLEDSSKLSSHNFFEESTYVNSQNKVQPCYLLTKKGCDIVANKMTGSKGILFTA 94
Cdd:pfam09669   1 TTSLEVAELFGKRHKNVLRDIRKLIKDLEEFGEDFRELNFEESPYKDSQGRKRPCYLLTRDGFTLLAMGFTGKKAVEFKA 80

                          90
                  ....*....|.
gi 616418378   95 TYVDAFHKMDE 105
Cdd:pfam09669  81 KYIKAFNEMEE 91
phage_pRha TIGR02681
phage regulatory protein, rha family; Members of this protein family are found in temperate ...
 15-111 6.07e-17

phage regulatory protein, rha family; Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that pRha is a phage regulatory protein. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 131728  Cd Length: 108  Bit Score: 74.08  E-value: 6.07e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616418378   15 VDSREVAEMIGKRHDNLVRDIKgyIKVLEDSSKLSSHNFFEESTYVNSQNKVQPCYLLTKKGCDIVANKMTGSKGILFTA 94
Cdd:TIGR02681  14 TDSLTMAQMFGKRHDNVIRDIK--VLLIEANETEFGQLNFEETQYQDEQNKKQPMFNLTEDGFTIVAMGYTTPKAMKMKE 91

                          90
                  ....*....|....*..
gi 616418378   95 TYVDAFHKMDEYIKQQA 111
Cdd:TIGR02681  92 KFIKEFNEMKEHLQKVQ 108
 
Name Accession Description Interval E-value
pRha COG3646
Phage regulatory protein Rha [Mobilome: prophages, transposons];
1-171 3.24e-35

Phage regulatory protein Rha [Mobilome: prophages, transposons];


Pssm-ID: 442863 [Multi-domain]  Cd Length: 211  Bit Score: 125.11  E-value: 3.24e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616418378   1 MQALQIV-EQNETHYVDSREVAEMIGKRHDNLVRDIKGYIKVLEdSSKLSSHNFfEESTYVNSQN-KVQPCYLLTKKGCD 78
Cdd:COG3646    1 MNQLELVtIKNGEPVTSSREIAELFGKRHKNVLRDIRKLISDLE-SPEFGQLNF-EESTYEDSQNgRERPEYLLTKDGFT 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616418378  79 IVANKMTGSKGILFTATYVDAFHKMDEYIKQQAQLnvPQTPMQALEMMFKAQKDQEQFNKQMQQEITGIRHIVGIETKNW 158
Cdd:COG3646   79 LLVMGFTGKKAAEFKAAYIDRFNEMEEQLKQQSAL--PQTLTEALRALAEQEEEKEAALLLGLALAAAAARALAEQSEAE 156

                        170
                 ....*....|...
gi 616418378 159 RNDTNKMLSAIAQ 171
Cdd:COG3646  157 QTGVKLLLALRAK 169
Phage_pRha pfam09669
Phage regulatory protein Rha (Phage_pRha); Members of this protein family are found in ...
 15-105 8.50e-33

Phage regulatory protein Rha (Phage_pRha); Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that Rha is a phage regulatory protein.


Pssm-ID: 462849 [Multi-domain]  Cd Length: 91  Bit Score: 115.01  E-value: 8.50e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616418378   15 VDSREVAEMIGKRHDNLVRDIKGYIKVLEDSSKLSSHNFFEESTYVNSQNKVQPCYLLTKKGCDIVANKMTGSKGILFTA 94
Cdd:pfam09669   1 TTSLEVAELFGKRHKNVLRDIRKLIKDLEEFGEDFRELNFEESPYKDSQGRKRPCYLLTRDGFTLLAMGFTGKKAVEFKA 80

                          90
                  ....*....|.
gi 616418378   95 TYVDAFHKMDE 105
Cdd:pfam09669  81 KYIKAFNEMEE 91
phage_pRha TIGR02681
phage regulatory protein, rha family; Members of this protein family are found in temperate ...
 15-111 6.07e-17

phage regulatory protein, rha family; Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that pRha is a phage regulatory protein. [Mobile and extrachromosomal element functions, Prophage functions]


Pssm-ID: 131728  Cd Length: 108  Bit Score: 74.08  E-value: 6.07e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 616418378   15 VDSREVAEMIGKRHDNLVRDIKgyIKVLEDSSKLSSHNFFEESTYVNSQNKVQPCYLLTKKGCDIVANKMTGSKGILFTA 94
Cdd:TIGR02681  14 TDSLTMAQMFGKRHDNVIRDIK--VLLIEANETEFGQLNFEETQYQDEQNKKQPMFNLTEDGFTIVAMGYTTPKAMKMKE 91

                          90
                  ....*....|....*..
gi 616418378   95 TYVDAFHKMDEYIKQQA 111
Cdd:TIGR02681  92 KFIKEFNEMKEHLQKVQ 108
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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