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Conserved domains on  [gi|1903834682|dbj|GGS48032|]
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NAD-glutamate dehydrogenase [Streptomyces cinerochromogenes]

Protein Classification

NAD-glutamate dehydrogenase( domain architecture ID 11458462)

NAD-specific glutamate dehydrogenase is involved in arginine catabolism by converting L-glutamate into 2-oxoglutarate, which is then channeled into the tricarboxylic acid cycle; can also utilize other amino acids of the glutamate family

EC:  1.4.1.2
Gene Ontology:  GO:0004352
PubMed:  10924516

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Gdh2 COG2902
NAD-specific glutamate dehydrogenase [Amino acid transport and metabolism];
1-1646 0e+00

NAD-specific glutamate dehydrogenase [Amino acid transport and metabolism];


:

Pssm-ID: 442147 [Multi-domain]  Cd Length: 1607  Bit Score: 2758.48  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682    1 MQTklDEAKAELLERAARVAENspvggHLPTgttsegtpgtPDSESVLAFLQRYYLHTAPEDLADRDPVDVFGAAVSHYR 80
Cdd:COG2902      1 MTS--EASKAELLEAVAELIAE-----RLPA----------AQAPLVAAFARQYYRHVPPEDLAARSPEDLYGAALSHWQ 63

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682   81 LAENRPQGTANVRVHTPTVEENGWTCSHTVVEVVTDDMPFLVDSVTNELTRQGRGIHVVVHPQFVVRRDLTGKLIEVLPT 160
Cdd:COG2902     64 LAQQRKPGEPKVRVFNPDLEEHGWQSTHTVVEIVTDDMPFLVDSVTMELNRLGLTIHLVVHPVLAVERDADGELVEVLPA 143

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  161 RSTefigdlPHDAHVESWIHVEIDRETDRSDLKQITTDLLRVLSDVREAVEDWEKMRDAATRIADDLEGEPVPgdLPRPE 240
Cdd:COG2902    144 DEA------PADGLRESLIHIEIDRQTDPEALEELEAELERVLADVRAAVEDWPAMRARLLEIAAELEAAPPP--VDADE 215

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  241 VEEARELLHWLSADHFTFLGYREYQLR---DDDTLAAVPGTGLGILRSDPHHAEddqhpvSPSFERLPADARAKAREHKL 317
Cdd:COG2902    216 VAEAAAFLRWLADDHFTFLGYREYDLVgedGDDVLRPVPGSGLGILRDDSVRVR------GRSLSALPPEARAFAREPDL 289

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  318 LVLTKANSRATVHRPSYLDYIGVKKFDADGNVVGERRFLGLFSSAAYTESVRRVPVIRRKVDEVLERAGFSPNSHDGRDL 397
Cdd:COG2902    290 LILTKANSRSTVHRPAYLDYIGVKRFDADGEVIGERRFLGLFTSTAYNESVRDIPLLRRKVEAVLERSGFDPGSHSGKAL 369

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  398 LQILETYPRDELFQTPVAELQSIVTSVLYLQERRRLRLYLRQDEYGRYYSALVYLPRDRYTTGVRLRIIDILKEELGGTS 477
Cdd:COG2902    370 LNILETYPRDELFQISEDELLETALGILHLQERRRVRLFLRRDPFGRFVSCLVYVPRDRYNTELRLRIQAILAEAFGGES 449

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  478 VDFTAWNTESILSRLHFVVRVPQGTELpqlsDSDKERIEARLVEAARSWADSFAEALTAECGEERAAEVLRRYNHAFPEG 557
Cdd:COG2902    450 VEFTTYFSESVLARVHFIVRVDPGELP----DVDVAELEARLAEAARSWEDDLREALVERFGEERGNRLARRYADAFPAG 525

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  558 YKADHSPRAAVADLVHMEQLGDGKTFSLSLYEPVGAAPDERRFKIYQKGGSVSLSKVLPVLSRLGVEVTDERPYELRCAD 637
Cdd:COG2902    526 YREDFSPRTAVADIERLESLSEEGPLAMSLYRPLEADPGELRLKLYHRGEPIPLSDVLPVLENMGLRVIDERPYEIEPAD 605

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  638 RTTAWIYDFGLRmpkPPGGHNGDYlgDDARERFQDAFAATWTGKAENDGFNALVLSAGLTWRQAMVLRAYAKYLRQAGST 717
Cdd:COG2902    606 GEPVWIHDFGLE---YPGGGEIDL--DEVRELFEDAFAAVWRGEAENDGFNRLVLAAGLTWREVAVLRAYARYLRQIGFP 680

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  718 FSQDYMEDTLRNNVHTTRLLVSLFEARMSPDRQQAGLE-ITDALLEELDAALEQVASLDEDRILRSFLTVIKATLRTNFF 796
Cdd:COG2902    681 FSQDYIEDTLARHPAIARLLVELFEARFDPARDDDDREeRAAALREEIEAALDEVASLDEDRILRRFLNLIQATLRTNFY 760

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  797 QEALGGQPHDYVSMKFDPQAIPDLPAPRPAYEIWVYSPRVEGVHLRFGKVARGGLRWSDRREDFRTEILGLVKAQMVKNT 876
Cdd:COG2902    761 QRDADGQPKPYLSFKLDPRKIPDLPLPRPMFEIFVYSPRVEGVHLRGGKVARGGLRWSDRREDFRTEVLGLVKAQMVKNA 840

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  877 VIVPVGAKGGFVAKQLPDPGvDRDAWLAEGVASYKTFISALLDITDNMVAGEVVPPQDVVRHDGDDTYLVVAADKGTATF 956
Cdd:COG2902    841 VIVPVGAKGGFVVKRLPAPG-DREAWLAEGIACYKTFIRGLLDITDNLVGGEVVPPEDVVRHDGDDPYLVVAADKGTATF 919

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  957 SDIANEVANTYNFWLGDAFASGGSAGYDHKGMGITARGAWESVKRHFRELGVDTQSEDFTVVGIGDMSGDVFGNGMLLSE 1036
Cdd:COG2902    920 SDIANGISAEYGFWLGDAFASGGSVGYDHKKMGITARGAWESVKRHFRELGIDIQTEDFTVVGIGDMSGDVFGNGMLLSE 999

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1037 HIRLVAAFDHRHIFIDPTPDAAVSYAERRRLFELPRSSWADYNTDLLSAGGGIFPRTAKSIPLNSHIREALGIEgkVTKM 1116
Cdd:COG2902   1000 HIRLVAAFDHRHIFIDPNPDAAASFAERKRLFELPRSSWADYDKSLISKGGGVFSRSAKSIPLSPEMRAALGIE--VDSL 1077

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1117 TPADLMKTILKAPVDLLWNGGIGTYVKASSESNADVGDKANDAIRVDGADLRVKVVGEGGNLGLTQLGRIEFALHGGRIN 1196
Cdd:COG2902   1078 TPNELIRAILKAPVDLLWNGGIGTYVKASTESHADVGDRANDALRVNGSELRAKVVGEGGNLGLTQLGRIEYALNGGRIN 1157

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1197 TDAIDNSAGVDTSDHEVNIKILLNGLVADGDMTVKQRNKLLAEMTDEVGALVLRNNYAQNTALANALFQAKDMLHAQQRF 1276
Cdd:COG2902   1158 TDAIDNSAGVDCSDHEVNIKILLNRLVADGDLTLKQRNKLLAEMTDEVAELVLRDNYRQTQALSLAEAQAAERLGEHARF 1237

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1277 IRHLVREGHLDRALEFLPTDRQIRERLAGGQGLTGPETAVVLAYTKITVAEELLHTSLPDDAYLRGLLHAYFPTALRERF 1356
Cdd:COG2902   1238 IRALERAGRLDRALEFLPSDEELAERRAAGQGLTRPELAVLLAYAKIVLKDELLASDLPDDPYLARELVRYFPKPLRERF 1317

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1357 AEAIDNHPLRREITTTVLVNDTVNTGGTTYLHRLREETGASLEEIVRAQTAARAIFCSAPVWDAVEALDNKVDADVQTRI 1436
Cdd:COG2902   1318 ADEIAEHPLRREIIATQLANDMVNRMGITFVFRLQEETGASAADIARAYVIAREVFGLPALWAAIEALDNKVPADVQLEM 1397

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1437 RLHSRRLVERGTRWLLNNRPQPLQLAETVEFFAERVERVWQELPKLLRGADLEWYQHVYDELSEAGVPDELATRVAGFSS 1516
Cdd:COG2902   1398 LLEVRRLLRRATRWFLRNRRQPLDIAAVIERFRPGVAALRPALPELLPGEEREALEARAAELVEAGVPEDLARRIAALPY 1477

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1517 AFPTLDIVSVADRTGKEPLDVAEIYYDLADRLNITQLMDRIIELPRADRWQSMARASIREDLYAAHAALTADVLAVGNGT 1596
Cdd:COG2902   1478 LYSALDIVEVAEETGRDVAEVARVYFALGDRLGLDWLREQISALPVDDRWQALARAALRDDLYAQQRALTAAVLRSTDPG 1557

                         1610      1620      1630      1640      1650
                   ....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1597 STPEQRFKAWEQKNAAILSRARTTLDEIRSSDSFDLANLSVAMRTMRTLL 1646
Cdd:COG2902   1558 EDAEERVEAWLEANAAALERWRQMLAEIRASGTLDLAMLSVALRELRDLA 1607
 
Name Accession Description Interval E-value
Gdh2 COG2902
NAD-specific glutamate dehydrogenase [Amino acid transport and metabolism];
1-1646 0e+00

NAD-specific glutamate dehydrogenase [Amino acid transport and metabolism];


Pssm-ID: 442147 [Multi-domain]  Cd Length: 1607  Bit Score: 2758.48  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682    1 MQTklDEAKAELLERAARVAENspvggHLPTgttsegtpgtPDSESVLAFLQRYYLHTAPEDLADRDPVDVFGAAVSHYR 80
Cdd:COG2902      1 MTS--EASKAELLEAVAELIAE-----RLPA----------AQAPLVAAFARQYYRHVPPEDLAARSPEDLYGAALSHWQ 63

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682   81 LAENRPQGTANVRVHTPTVEENGWTCSHTVVEVVTDDMPFLVDSVTNELTRQGRGIHVVVHPQFVVRRDLTGKLIEVLPT 160
Cdd:COG2902     64 LAQQRKPGEPKVRVFNPDLEEHGWQSTHTVVEIVTDDMPFLVDSVTMELNRLGLTIHLVVHPVLAVERDADGELVEVLPA 143

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  161 RSTefigdlPHDAHVESWIHVEIDRETDRSDLKQITTDLLRVLSDVREAVEDWEKMRDAATRIADDLEGEPVPgdLPRPE 240
Cdd:COG2902    144 DEA------PADGLRESLIHIEIDRQTDPEALEELEAELERVLADVRAAVEDWPAMRARLLEIAAELEAAPPP--VDADE 215

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  241 VEEARELLHWLSADHFTFLGYREYQLR---DDDTLAAVPGTGLGILRSDPHHAEddqhpvSPSFERLPADARAKAREHKL 317
Cdd:COG2902    216 VAEAAAFLRWLADDHFTFLGYREYDLVgedGDDVLRPVPGSGLGILRDDSVRVR------GRSLSALPPEARAFAREPDL 289

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  318 LVLTKANSRATVHRPSYLDYIGVKKFDADGNVVGERRFLGLFSSAAYTESVRRVPVIRRKVDEVLERAGFSPNSHDGRDL 397
Cdd:COG2902    290 LILTKANSRSTVHRPAYLDYIGVKRFDADGEVIGERRFLGLFTSTAYNESVRDIPLLRRKVEAVLERSGFDPGSHSGKAL 369

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  398 LQILETYPRDELFQTPVAELQSIVTSVLYLQERRRLRLYLRQDEYGRYYSALVYLPRDRYTTGVRLRIIDILKEELGGTS 477
Cdd:COG2902    370 LNILETYPRDELFQISEDELLETALGILHLQERRRVRLFLRRDPFGRFVSCLVYVPRDRYNTELRLRIQAILAEAFGGES 449

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  478 VDFTAWNTESILSRLHFVVRVPQGTELpqlsDSDKERIEARLVEAARSWADSFAEALTAECGEERAAEVLRRYNHAFPEG 557
Cdd:COG2902    450 VEFTTYFSESVLARVHFIVRVDPGELP----DVDVAELEARLAEAARSWEDDLREALVERFGEERGNRLARRYADAFPAG 525

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  558 YKADHSPRAAVADLVHMEQLGDGKTFSLSLYEPVGAAPDERRFKIYQKGGSVSLSKVLPVLSRLGVEVTDERPYELRCAD 637
Cdd:COG2902    526 YREDFSPRTAVADIERLESLSEEGPLAMSLYRPLEADPGELRLKLYHRGEPIPLSDVLPVLENMGLRVIDERPYEIEPAD 605

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  638 RTTAWIYDFGLRmpkPPGGHNGDYlgDDARERFQDAFAATWTGKAENDGFNALVLSAGLTWRQAMVLRAYAKYLRQAGST 717
Cdd:COG2902    606 GEPVWIHDFGLE---YPGGGEIDL--DEVRELFEDAFAAVWRGEAENDGFNRLVLAAGLTWREVAVLRAYARYLRQIGFP 680

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  718 FSQDYMEDTLRNNVHTTRLLVSLFEARMSPDRQQAGLE-ITDALLEELDAALEQVASLDEDRILRSFLTVIKATLRTNFF 796
Cdd:COG2902    681 FSQDYIEDTLARHPAIARLLVELFEARFDPARDDDDREeRAAALREEIEAALDEVASLDEDRILRRFLNLIQATLRTNFY 760

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  797 QEALGGQPHDYVSMKFDPQAIPDLPAPRPAYEIWVYSPRVEGVHLRFGKVARGGLRWSDRREDFRTEILGLVKAQMVKNT 876
Cdd:COG2902    761 QRDADGQPKPYLSFKLDPRKIPDLPLPRPMFEIFVYSPRVEGVHLRGGKVARGGLRWSDRREDFRTEVLGLVKAQMVKNA 840

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  877 VIVPVGAKGGFVAKQLPDPGvDRDAWLAEGVASYKTFISALLDITDNMVAGEVVPPQDVVRHDGDDTYLVVAADKGTATF 956
Cdd:COG2902    841 VIVPVGAKGGFVVKRLPAPG-DREAWLAEGIACYKTFIRGLLDITDNLVGGEVVPPEDVVRHDGDDPYLVVAADKGTATF 919

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  957 SDIANEVANTYNFWLGDAFASGGSAGYDHKGMGITARGAWESVKRHFRELGVDTQSEDFTVVGIGDMSGDVFGNGMLLSE 1036
Cdd:COG2902    920 SDIANGISAEYGFWLGDAFASGGSVGYDHKKMGITARGAWESVKRHFRELGIDIQTEDFTVVGIGDMSGDVFGNGMLLSE 999

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1037 HIRLVAAFDHRHIFIDPTPDAAVSYAERRRLFELPRSSWADYNTDLLSAGGGIFPRTAKSIPLNSHIREALGIEgkVTKM 1116
Cdd:COG2902   1000 HIRLVAAFDHRHIFIDPNPDAAASFAERKRLFELPRSSWADYDKSLISKGGGVFSRSAKSIPLSPEMRAALGIE--VDSL 1077

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1117 TPADLMKTILKAPVDLLWNGGIGTYVKASSESNADVGDKANDAIRVDGADLRVKVVGEGGNLGLTQLGRIEFALHGGRIN 1196
Cdd:COG2902   1078 TPNELIRAILKAPVDLLWNGGIGTYVKASTESHADVGDRANDALRVNGSELRAKVVGEGGNLGLTQLGRIEYALNGGRIN 1157

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1197 TDAIDNSAGVDTSDHEVNIKILLNGLVADGDMTVKQRNKLLAEMTDEVGALVLRNNYAQNTALANALFQAKDMLHAQQRF 1276
Cdd:COG2902   1158 TDAIDNSAGVDCSDHEVNIKILLNRLVADGDLTLKQRNKLLAEMTDEVAELVLRDNYRQTQALSLAEAQAAERLGEHARF 1237

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1277 IRHLVREGHLDRALEFLPTDRQIRERLAGGQGLTGPETAVVLAYTKITVAEELLHTSLPDDAYLRGLLHAYFPTALRERF 1356
Cdd:COG2902   1238 IRALERAGRLDRALEFLPSDEELAERRAAGQGLTRPELAVLLAYAKIVLKDELLASDLPDDPYLARELVRYFPKPLRERF 1317

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1357 AEAIDNHPLRREITTTVLVNDTVNTGGTTYLHRLREETGASLEEIVRAQTAARAIFCSAPVWDAVEALDNKVDADVQTRI 1436
Cdd:COG2902   1318 ADEIAEHPLRREIIATQLANDMVNRMGITFVFRLQEETGASAADIARAYVIAREVFGLPALWAAIEALDNKVPADVQLEM 1397

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1437 RLHSRRLVERGTRWLLNNRPQPLQLAETVEFFAERVERVWQELPKLLRGADLEWYQHVYDELSEAGVPDELATRVAGFSS 1516
Cdd:COG2902   1398 LLEVRRLLRRATRWFLRNRRQPLDIAAVIERFRPGVAALRPALPELLPGEEREALEARAAELVEAGVPEDLARRIAALPY 1477

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1517 AFPTLDIVSVADRTGKEPLDVAEIYYDLADRLNITQLMDRIIELPRADRWQSMARASIREDLYAAHAALTADVLAVGNGT 1596
Cdd:COG2902   1478 LYSALDIVEVAEETGRDVAEVARVYFALGDRLGLDWLREQISALPVDDRWQALARAALRDDLYAQQRALTAAVLRSTDPG 1557

                         1610      1620      1630      1640      1650
                   ....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1597 STPEQRFKAWEQKNAAILSRARTTLDEIRSSDSFDLANLSVAMRTMRTLL 1646
Cdd:COG2902   1558 EDAEERVEAWLEANAAALERWRQMLAEIRASGTLDLAMLSVALRELRDLA 1607
Bac_GDH pfam05088
Bacterial NAD-glutamate dehydrogenase; This family consists of several bacterial proteins ...
 92-1644 0e+00

Bacterial NAD-glutamate dehydrogenase; This family consists of several bacterial proteins which are closely related to NAD-glutamate dehydrogenase found in Streptomyces clavuligerus. Glutamate dehydrogenases (GDHs) are a broadly distributed group of enzymes that catalyze the reversible oxidative deamination of glutamate to ketoglutarate and ammonia.


Pssm-ID: 428297 [Multi-domain]  Cd Length: 1530  Bit Score: 2683.02  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682   92 VRVHTPTVEENGWTCSHTVVEVVTDDMPFLVDSVTNELTRQGRGIHVVVHPQFVVRRDLTGKLIEVLPTrstefiGDLPH 171
Cdd:pfam05088    1 VRVFNPDLEEHGWQSTHTVVEIVNDDMPFLVDSVTMELNRQGLTIHLVVHPVLVVRRDADGKLVEVLPA------ADAAA 74

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  172 DAHVESWIHVEIDRETDRSDLKQITTDLLRVLSDVREAVEDWEKMRDAATRIADDLEGEPVPgdLPRPEVEEARELLHWL 251
Cdd:pfam05088   75 GAAGESLIHIEIDRQTDPERLEALEAELERVLADVRAAVEDWPAMRARLLAIAAELETAPPP--VSADEVEEAAAFLRWL 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  252 SADHFTFLGYREYQLR---DDDTLAAVPGTGLGILRSDPHHaeddqhPVSPSFERLPADARAKAREHKLLVLTKANSRAT 328
Cdd:pfam05088  153 ADDHFTFLGYREYDLVedeGGGVLRAVPGSGLGILRDDSVL------PRSRSLAALPPEARAFALEPELLILTKANSRST 226

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  329 VHRPSYLDYIGVKKFDADGNVVGERRFLGLFSSAAYTESVRRVPVIRRKVDEVLERAGFSPNSHDGRDLLQILETYPRDE 408
Cdd:pfam05088  227 VHRPAYLDYVGVKRFDADGEVIGERRFLGLFTSTAYNESPREIPLLRRKVARVLERSGFDPGSHSGKALLNILETYPRDE 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  409 LFQTPVAELQSIVTSVLYLQERRRLRLYLRQDEYGRYYSALVYLPRDRYTTGVRLRIIDILKEELGGTSVDFTAWNTESI 488
Cdd:pfam05088  307 LFQISEDELLEIALGILHLQERRRVRLFLRRDPFGRFVSCLVYVPRDRYNTELRLRIQAILAEALGGTDVEFTTYFSESV 386

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  489 LSRLHFVVRVPQGTelpqLSDSDKERIEARLVEAARSWADSFAEALTAECGEERAAEVLRRYNHAFPEGYKADHSPRAAV 568
Cdd:pfam05088  387 LARLHFIVRVDPGN----PPEVDVAELEARLAEAARSWEDDLREALVEAHGEERGNRLARRYADAFPAAYKEDFSPRSAV 462

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  569 ADLVHMEQLGDGKTFSLSLYEPVGAAPDERRFKIYQKGGSVSLSKVLPVLSRLGVEVTDERPYELRCADRTTAWIYDFGL 648
Cdd:pfam05088  463 ADIERLEALSEEGDLAMSLYRPLEADPGELRLKLYRRGEPLPLSDVLPMLENMGLRVIDERPYEIRPADGKRVWIHDFGL 542

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  649 RmpkPPGGHNGDylGDDARERFQDAFAATWTGKAENDGFNALVLSAGLTWRQAMVLRAYAKYLRQAGSTFSQDYMEDTLR 728
Cdd:pfam05088  543 R---YAGGAALD--LDEVRELFEDAFAAVWRGEAENDGFNRLVLRAGLTWREVAVLRAYARYLRQIGFTFSQDYIEDTLA 617

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  729 NNVHTTRLLVSLFEARMSPDRQQAGLEITDALLEELDAALEQVASLDEDRILRSFLTVIKATLRTNFFQEALGGQPHDYV 808
Cdd:pfam05088  618 AHPDIARLLVALFEARFDPALAAGREARAEALEAEILAALDEVASLDEDRILRRYLNLIEATLRTNFYQRDADGQPKPYI 697

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  809 SMKFDPQAIPDLPAPRPAYEIWVYSPRVEGVHLRFGKVARGGLRWSDRREDFRTEILGLVKAQMVKNTVIVPVGAKGGFV 888
Cdd:pfam05088  698 SFKLDPRAIPDLPLPRPMFEIFVYSPRVEGVHLRGGKVARGGLRWSDRREDFRTEVLGLVKAQMVKNAVIVPVGAKGGFV 777

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  889 AKQLPdPGVDRDAWLAEGVASYKTFISALLDITDNMVAGEVVPPQDVVRHDGDDTYLVVAADKGTATFSDIANEVANTYN 968
Cdd:pfam05088  778 VKRLP-PAGDREAWLAEGIACYKTFIRGLLDITDNLVDGEVVPPADVVRHDGDDPYLVVAADKGTATFSDIANGISAEYG 856

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  969 FWLGDAFASGGSAGYDHKGMGITARGAWESVKRHFRELGVDTQSEDFTVVGIGDMSGDVFGNGMLLSEHIRLVAAFDHRH 1048
Cdd:pfam05088  857 FWLGDAFASGGSVGYDHKKMGITARGAWESVKRHFRELGVDTQTEDFTVVGIGDMSGDVFGNGMLLSEHIRLVAAFNHRH 936

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1049 IFIDPTPDAAVSYAERRRLFELPRSSWADYNTDLLSAGGGIFPRTAKSIPLNSHIREALGIEGKVtkMTPADLMKTILKA 1128
Cdd:pfam05088  937 IFIDPDPDAAASFAERKRLFELPRSSWADYDRSLISAGGGVFPRSAKSIPLSPEMRAALGIEKDV--LTPNELIRAILKA 1014

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1129 PVDLLWNGGIGTYVKASSESNADVGDKANDAIRVDGADLRVKVVGEGGNLGLTQLGRIEFALHGGRINTDAIDNSAGVDT 1208
Cdd:pfam05088 1015 PVDLLWNGGIGTYVKASTETHADVGDKANDALRVNGSELRAKVVGEGGNLGLTQLGRIEYALNGGRINTDAIDNSAGVDC 1094

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1209 SDHEVNIKILLNGLVADGDMTVKQRNKLLAEMTDEVGALVLRNNYAQNTALANALFQAKDMLHAQQRFIRHLVREGHLDR 1288
Cdd:pfam05088 1095 SDHEVNIKILLNGVVAAGDLTLKQRNALLAEMTDEVAELVLRDNYRQTQALSLAEAQAAERLDEHARLIRALEREGRLDR 1174

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1289 ALEFLPTDRQIRERLAGGQGLTGPETAVVLAYTKITVAEELLHTSLPDDAYLRGLLHAYFPTALRERFAEAIDNHPLRRE 1368
Cdd:pfam05088 1175 ALEFLPSDEELAERKAAGQGLTRPELAVLLAYAKIVLKDELLASDLPDDPYLARELVRYFPTPLRERFAEAIARHPLRRE 1254

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1369 ITTTVLVNDTVNTGGTTYLHRLREETGASLEEIVRAQTAARAIFCSAPVWDAVEALDNKVDADVQTRIRLHSRRLVERGT 1448
Cdd:pfam05088 1255 IIATQLANDMVNRMGITFVFRLQEETGASVADVARAYVIAREVFGLPELWAQIEALDNKVPAAVQTEMLLEVRRLVRRAT 1334

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1449 RWLLNNRPQPLQLAETVEFFAERVERVWQELPKLLRGADLEWYQHVYDELSEAGVPDELATRVAGFSSAFPTLDIVSVAD 1528
Cdd:pfam05088 1335 RWLLRNRRQPLDIAATIARFAPGVAALAAQLPELLPGAEREALQARAARLVEAGVPEELARRVAGLPYLYSALDIVEVAE 1414

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1529 RTGKEPLDVAEIYYDLADRLNITQLMDRIIELPRADRWQSMARASIREDLYAAHAALTADVLAVGNGTSTPEQRFKAWEQ 1608
Cdd:pfam05088 1415 ATGRDLEEVARVYFALGDRLGLDWLREQISALPVDNRWQALARAALRDDLYAQQRALTASVLASSDPDGDAEARVAAWLE 1494

                         1530      1540      1550
                   ....*....|....*....|....*....|....*.
gi 1903834682 1609 KNAAILSRARTTLDEIRSSDSFDLANLSVAMRTMRT 1644
Cdd:pfam05088 1495 ANAAALERWRAMLAEIRASSGLDLAMLSVALRELRD 1530
PTZ00324 PTZ00324
glutamate dehydrogenase 2; Provisional
 717-1231 1.06e-22

glutamate dehydrogenase 2; Provisional


Pssm-ID: 240359 [Multi-domain]  Cd Length: 1002  Bit Score: 106.04  E-value: 1.06e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  717 TFSQDYMEDTLRNNVHTTRLLVSLFEARMSPDRQQAGLEITDalleELDAALEQVASLDEDRILRSFLTVIKATLRTNFF 796
Cdd:PTZ00324   375 VFSERYIGEAIALYPEFVKLLYEDFRLGHTPERRAAITQKIE----ETARLKEDIRNELDRTIFSAFLSFNEHILKTNFY 450

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  797 QealggQPHDYVSMKFDPQAIPDLPAPRPAYEIW-VYSPRVEGVHLRFGKVARGGLRW--SDRREDFRT-------EILG 866
Cdd:PTZ00324   451 K-----TEKTALAFRLDPSFLSELEYPRVPYGVFlVAGAQFRGFHIRFTDIARGGVRMiqSFKEQAYRRnkrsvfdENYN 525

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  867 LVKAQMVKNTVIVPVGAKGGFvakqLPDPGVDRDAWLAEGVASYKTFISALLDItdnmvageVVPPQDVVRHDGDDTYLV 946
Cdd:PTZ00324   526 LASTQLLKNKDIPEGGSKGTI----LLSSRYLNKFAQVRCQHAFLQYIDALLDV--------MLPGEKVVDHLKQEEIIF 593

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  947 VAADK-GTATFSDIANEVANTYNFWLGDAFASGGS---AGYDHKGMGITARGAWESVKRHFRELGVDtqSEDFTVVGIGD 1022
Cdd:PTZ00324   594 LGPDEhTTGTLMDWAALHAKKRGYPFWKSFTTGKSpsmGGIPHDTYGMTTRSVRAYVTGILEKLGLN--EEEVTKFQTGG 671

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1023 MSGDVFGNGMLLSEHiRLVAAFDHRHIFIDPTpdaAVSYAERRRLFElPRSSWADYNTDLLSAGGGIFPRTAKSI--PLN 1100
Cdd:PTZ00324   672 PDGDLGSNELLLSKE-KTVGIVDGSGVLHDPE---GLNREELRRLAH-HRLPAREFDESKLSPQGFLVLTDDRDVklPDG 746

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1101 SHIREALGIEGK--VTKMTPADLMktilkAPVdllwnGGigtyvKASSESNADVGDKANDAirvdGADLRVKVVGEGGNL 1178
Cdd:PTZ00324   747 TIVESGLRFRNEfhLLPYSDADVF-----VPC-----GG-----RPRSVTLFNVGRFFDEK----NGKLRFKIIVEGANL 807

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1903834682 1179 GLTQLGRIEFALHGGRINTDAIDNSAGVDTSDHEVnikilLNGLVADGD-----MTVK 1231
Cdd:PTZ00324   808 FITQDARLALEECGVILFKDASANKGGVTSSSLEV-----LAALALSDEefaehMCVK 860
 
Name Accession Description Interval E-value
Gdh2 COG2902
NAD-specific glutamate dehydrogenase [Amino acid transport and metabolism];
1-1646 0e+00

NAD-specific glutamate dehydrogenase [Amino acid transport and metabolism];


Pssm-ID: 442147 [Multi-domain]  Cd Length: 1607  Bit Score: 2758.48  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682    1 MQTklDEAKAELLERAARVAENspvggHLPTgttsegtpgtPDSESVLAFLQRYYLHTAPEDLADRDPVDVFGAAVSHYR 80
Cdd:COG2902      1 MTS--EASKAELLEAVAELIAE-----RLPA----------AQAPLVAAFARQYYRHVPPEDLAARSPEDLYGAALSHWQ 63

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682   81 LAENRPQGTANVRVHTPTVEENGWTCSHTVVEVVTDDMPFLVDSVTNELTRQGRGIHVVVHPQFVVRRDLTGKLIEVLPT 160
Cdd:COG2902     64 LAQQRKPGEPKVRVFNPDLEEHGWQSTHTVVEIVTDDMPFLVDSVTMELNRLGLTIHLVVHPVLAVERDADGELVEVLPA 143

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  161 RSTefigdlPHDAHVESWIHVEIDRETDRSDLKQITTDLLRVLSDVREAVEDWEKMRDAATRIADDLEGEPVPgdLPRPE 240
Cdd:COG2902    144 DEA------PADGLRESLIHIEIDRQTDPEALEELEAELERVLADVRAAVEDWPAMRARLLEIAAELEAAPPP--VDADE 215

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  241 VEEARELLHWLSADHFTFLGYREYQLR---DDDTLAAVPGTGLGILRSDPHHAEddqhpvSPSFERLPADARAKAREHKL 317
Cdd:COG2902    216 VAEAAAFLRWLADDHFTFLGYREYDLVgedGDDVLRPVPGSGLGILRDDSVRVR------GRSLSALPPEARAFAREPDL 289

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  318 LVLTKANSRATVHRPSYLDYIGVKKFDADGNVVGERRFLGLFSSAAYTESVRRVPVIRRKVDEVLERAGFSPNSHDGRDL 397
Cdd:COG2902    290 LILTKANSRSTVHRPAYLDYIGVKRFDADGEVIGERRFLGLFTSTAYNESVRDIPLLRRKVEAVLERSGFDPGSHSGKAL 369

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  398 LQILETYPRDELFQTPVAELQSIVTSVLYLQERRRLRLYLRQDEYGRYYSALVYLPRDRYTTGVRLRIIDILKEELGGTS 477
Cdd:COG2902    370 LNILETYPRDELFQISEDELLETALGILHLQERRRVRLFLRRDPFGRFVSCLVYVPRDRYNTELRLRIQAILAEAFGGES 449

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  478 VDFTAWNTESILSRLHFVVRVPQGTELpqlsDSDKERIEARLVEAARSWADSFAEALTAECGEERAAEVLRRYNHAFPEG 557
Cdd:COG2902    450 VEFTTYFSESVLARVHFIVRVDPGELP----DVDVAELEARLAEAARSWEDDLREALVERFGEERGNRLARRYADAFPAG 525

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  558 YKADHSPRAAVADLVHMEQLGDGKTFSLSLYEPVGAAPDERRFKIYQKGGSVSLSKVLPVLSRLGVEVTDERPYELRCAD 637
Cdd:COG2902    526 YREDFSPRTAVADIERLESLSEEGPLAMSLYRPLEADPGELRLKLYHRGEPIPLSDVLPVLENMGLRVIDERPYEIEPAD 605

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  638 RTTAWIYDFGLRmpkPPGGHNGDYlgDDARERFQDAFAATWTGKAENDGFNALVLSAGLTWRQAMVLRAYAKYLRQAGST 717
Cdd:COG2902    606 GEPVWIHDFGLE---YPGGGEIDL--DEVRELFEDAFAAVWRGEAENDGFNRLVLAAGLTWREVAVLRAYARYLRQIGFP 680

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  718 FSQDYMEDTLRNNVHTTRLLVSLFEARMSPDRQQAGLE-ITDALLEELDAALEQVASLDEDRILRSFLTVIKATLRTNFF 796
Cdd:COG2902    681 FSQDYIEDTLARHPAIARLLVELFEARFDPARDDDDREeRAAALREEIEAALDEVASLDEDRILRRFLNLIQATLRTNFY 760

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  797 QEALGGQPHDYVSMKFDPQAIPDLPAPRPAYEIWVYSPRVEGVHLRFGKVARGGLRWSDRREDFRTEILGLVKAQMVKNT 876
Cdd:COG2902    761 QRDADGQPKPYLSFKLDPRKIPDLPLPRPMFEIFVYSPRVEGVHLRGGKVARGGLRWSDRREDFRTEVLGLVKAQMVKNA 840

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  877 VIVPVGAKGGFVAKQLPDPGvDRDAWLAEGVASYKTFISALLDITDNMVAGEVVPPQDVVRHDGDDTYLVVAADKGTATF 956
Cdd:COG2902    841 VIVPVGAKGGFVVKRLPAPG-DREAWLAEGIACYKTFIRGLLDITDNLVGGEVVPPEDVVRHDGDDPYLVVAADKGTATF 919

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  957 SDIANEVANTYNFWLGDAFASGGSAGYDHKGMGITARGAWESVKRHFRELGVDTQSEDFTVVGIGDMSGDVFGNGMLLSE 1036
Cdd:COG2902    920 SDIANGISAEYGFWLGDAFASGGSVGYDHKKMGITARGAWESVKRHFRELGIDIQTEDFTVVGIGDMSGDVFGNGMLLSE 999

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1037 HIRLVAAFDHRHIFIDPTPDAAVSYAERRRLFELPRSSWADYNTDLLSAGGGIFPRTAKSIPLNSHIREALGIEgkVTKM 1116
Cdd:COG2902   1000 HIRLVAAFDHRHIFIDPNPDAAASFAERKRLFELPRSSWADYDKSLISKGGGVFSRSAKSIPLSPEMRAALGIE--VDSL 1077

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1117 TPADLMKTILKAPVDLLWNGGIGTYVKASSESNADVGDKANDAIRVDGADLRVKVVGEGGNLGLTQLGRIEFALHGGRIN 1196
Cdd:COG2902   1078 TPNELIRAILKAPVDLLWNGGIGTYVKASTESHADVGDRANDALRVNGSELRAKVVGEGGNLGLTQLGRIEYALNGGRIN 1157

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1197 TDAIDNSAGVDTSDHEVNIKILLNGLVADGDMTVKQRNKLLAEMTDEVGALVLRNNYAQNTALANALFQAKDMLHAQQRF 1276
Cdd:COG2902   1158 TDAIDNSAGVDCSDHEVNIKILLNRLVADGDLTLKQRNKLLAEMTDEVAELVLRDNYRQTQALSLAEAQAAERLGEHARF 1237

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1277 IRHLVREGHLDRALEFLPTDRQIRERLAGGQGLTGPETAVVLAYTKITVAEELLHTSLPDDAYLRGLLHAYFPTALRERF 1356
Cdd:COG2902   1238 IRALERAGRLDRALEFLPSDEELAERRAAGQGLTRPELAVLLAYAKIVLKDELLASDLPDDPYLARELVRYFPKPLRERF 1317

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1357 AEAIDNHPLRREITTTVLVNDTVNTGGTTYLHRLREETGASLEEIVRAQTAARAIFCSAPVWDAVEALDNKVDADVQTRI 1436
Cdd:COG2902   1318 ADEIAEHPLRREIIATQLANDMVNRMGITFVFRLQEETGASAADIARAYVIAREVFGLPALWAAIEALDNKVPADVQLEM 1397

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1437 RLHSRRLVERGTRWLLNNRPQPLQLAETVEFFAERVERVWQELPKLLRGADLEWYQHVYDELSEAGVPDELATRVAGFSS 1516
Cdd:COG2902   1398 LLEVRRLLRRATRWFLRNRRQPLDIAAVIERFRPGVAALRPALPELLPGEEREALEARAAELVEAGVPEDLARRIAALPY 1477

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1517 AFPTLDIVSVADRTGKEPLDVAEIYYDLADRLNITQLMDRIIELPRADRWQSMARASIREDLYAAHAALTADVLAVGNGT 1596
Cdd:COG2902   1478 LYSALDIVEVAEETGRDVAEVARVYFALGDRLGLDWLREQISALPVDDRWQALARAALRDDLYAQQRALTAAVLRSTDPG 1557

                         1610      1620      1630      1640      1650
                   ....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1597 STPEQRFKAWEQKNAAILSRARTTLDEIRSSDSFDLANLSVAMRTMRTLL 1646
Cdd:COG2902   1558 EDAEERVEAWLEANAAALERWRQMLAEIRASGTLDLAMLSVALRELRDLA 1607
Bac_GDH pfam05088
Bacterial NAD-glutamate dehydrogenase; This family consists of several bacterial proteins ...
 92-1644 0e+00

Bacterial NAD-glutamate dehydrogenase; This family consists of several bacterial proteins which are closely related to NAD-glutamate dehydrogenase found in Streptomyces clavuligerus. Glutamate dehydrogenases (GDHs) are a broadly distributed group of enzymes that catalyze the reversible oxidative deamination of glutamate to ketoglutarate and ammonia.


Pssm-ID: 428297 [Multi-domain]  Cd Length: 1530  Bit Score: 2683.02  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682   92 VRVHTPTVEENGWTCSHTVVEVVTDDMPFLVDSVTNELTRQGRGIHVVVHPQFVVRRDLTGKLIEVLPTrstefiGDLPH 171
Cdd:pfam05088    1 VRVFNPDLEEHGWQSTHTVVEIVNDDMPFLVDSVTMELNRQGLTIHLVVHPVLVVRRDADGKLVEVLPA------ADAAA 74

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  172 DAHVESWIHVEIDRETDRSDLKQITTDLLRVLSDVREAVEDWEKMRDAATRIADDLEGEPVPgdLPRPEVEEARELLHWL 251
Cdd:pfam05088   75 GAAGESLIHIEIDRQTDPERLEALEAELERVLADVRAAVEDWPAMRARLLAIAAELETAPPP--VSADEVEEAAAFLRWL 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  252 SADHFTFLGYREYQLR---DDDTLAAVPGTGLGILRSDPHHaeddqhPVSPSFERLPADARAKAREHKLLVLTKANSRAT 328
Cdd:pfam05088  153 ADDHFTFLGYREYDLVedeGGGVLRAVPGSGLGILRDDSVL------PRSRSLAALPPEARAFALEPELLILTKANSRST 226

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  329 VHRPSYLDYIGVKKFDADGNVVGERRFLGLFSSAAYTESVRRVPVIRRKVDEVLERAGFSPNSHDGRDLLQILETYPRDE 408
Cdd:pfam05088  227 VHRPAYLDYVGVKRFDADGEVIGERRFLGLFTSTAYNESPREIPLLRRKVARVLERSGFDPGSHSGKALLNILETYPRDE 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  409 LFQTPVAELQSIVTSVLYLQERRRLRLYLRQDEYGRYYSALVYLPRDRYTTGVRLRIIDILKEELGGTSVDFTAWNTESI 488
Cdd:pfam05088  307 LFQISEDELLEIALGILHLQERRRVRLFLRRDPFGRFVSCLVYVPRDRYNTELRLRIQAILAEALGGTDVEFTTYFSESV 386

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  489 LSRLHFVVRVPQGTelpqLSDSDKERIEARLVEAARSWADSFAEALTAECGEERAAEVLRRYNHAFPEGYKADHSPRAAV 568
Cdd:pfam05088  387 LARLHFIVRVDPGN----PPEVDVAELEARLAEAARSWEDDLREALVEAHGEERGNRLARRYADAFPAAYKEDFSPRSAV 462

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  569 ADLVHMEQLGDGKTFSLSLYEPVGAAPDERRFKIYQKGGSVSLSKVLPVLSRLGVEVTDERPYELRCADRTTAWIYDFGL 648
Cdd:pfam05088  463 ADIERLEALSEEGDLAMSLYRPLEADPGELRLKLYRRGEPLPLSDVLPMLENMGLRVIDERPYEIRPADGKRVWIHDFGL 542

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  649 RmpkPPGGHNGDylGDDARERFQDAFAATWTGKAENDGFNALVLSAGLTWRQAMVLRAYAKYLRQAGSTFSQDYMEDTLR 728
Cdd:pfam05088  543 R---YAGGAALD--LDEVRELFEDAFAAVWRGEAENDGFNRLVLRAGLTWREVAVLRAYARYLRQIGFTFSQDYIEDTLA 617

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  729 NNVHTTRLLVSLFEARMSPDRQQAGLEITDALLEELDAALEQVASLDEDRILRSFLTVIKATLRTNFFQEALGGQPHDYV 808
Cdd:pfam05088  618 AHPDIARLLVALFEARFDPALAAGREARAEALEAEILAALDEVASLDEDRILRRYLNLIEATLRTNFYQRDADGQPKPYI 697

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  809 SMKFDPQAIPDLPAPRPAYEIWVYSPRVEGVHLRFGKVARGGLRWSDRREDFRTEILGLVKAQMVKNTVIVPVGAKGGFV 888
Cdd:pfam05088  698 SFKLDPRAIPDLPLPRPMFEIFVYSPRVEGVHLRGGKVARGGLRWSDRREDFRTEVLGLVKAQMVKNAVIVPVGAKGGFV 777

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  889 AKQLPdPGVDRDAWLAEGVASYKTFISALLDITDNMVAGEVVPPQDVVRHDGDDTYLVVAADKGTATFSDIANEVANTYN 968
Cdd:pfam05088  778 VKRLP-PAGDREAWLAEGIACYKTFIRGLLDITDNLVDGEVVPPADVVRHDGDDPYLVVAADKGTATFSDIANGISAEYG 856

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  969 FWLGDAFASGGSAGYDHKGMGITARGAWESVKRHFRELGVDTQSEDFTVVGIGDMSGDVFGNGMLLSEHIRLVAAFDHRH 1048
Cdd:pfam05088  857 FWLGDAFASGGSVGYDHKKMGITARGAWESVKRHFRELGVDTQTEDFTVVGIGDMSGDVFGNGMLLSEHIRLVAAFNHRH 936

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1049 IFIDPTPDAAVSYAERRRLFELPRSSWADYNTDLLSAGGGIFPRTAKSIPLNSHIREALGIEGKVtkMTPADLMKTILKA 1128
Cdd:pfam05088  937 IFIDPDPDAAASFAERKRLFELPRSSWADYDRSLISAGGGVFPRSAKSIPLSPEMRAALGIEKDV--LTPNELIRAILKA 1014

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1129 PVDLLWNGGIGTYVKASSESNADVGDKANDAIRVDGADLRVKVVGEGGNLGLTQLGRIEFALHGGRINTDAIDNSAGVDT 1208
Cdd:pfam05088 1015 PVDLLWNGGIGTYVKASTETHADVGDKANDALRVNGSELRAKVVGEGGNLGLTQLGRIEYALNGGRINTDAIDNSAGVDC 1094

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1209 SDHEVNIKILLNGLVADGDMTVKQRNKLLAEMTDEVGALVLRNNYAQNTALANALFQAKDMLHAQQRFIRHLVREGHLDR 1288
Cdd:pfam05088 1095 SDHEVNIKILLNGVVAAGDLTLKQRNALLAEMTDEVAELVLRDNYRQTQALSLAEAQAAERLDEHARLIRALEREGRLDR 1174

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1289 ALEFLPTDRQIRERLAGGQGLTGPETAVVLAYTKITVAEELLHTSLPDDAYLRGLLHAYFPTALRERFAEAIDNHPLRRE 1368
Cdd:pfam05088 1175 ALEFLPSDEELAERKAAGQGLTRPELAVLLAYAKIVLKDELLASDLPDDPYLARELVRYFPTPLRERFAEAIARHPLRRE 1254

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1369 ITTTVLVNDTVNTGGTTYLHRLREETGASLEEIVRAQTAARAIFCSAPVWDAVEALDNKVDADVQTRIRLHSRRLVERGT 1448
Cdd:pfam05088 1255 IIATQLANDMVNRMGITFVFRLQEETGASVADVARAYVIAREVFGLPELWAQIEALDNKVPAAVQTEMLLEVRRLVRRAT 1334

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1449 RWLLNNRPQPLQLAETVEFFAERVERVWQELPKLLRGADLEWYQHVYDELSEAGVPDELATRVAGFSSAFPTLDIVSVAD 1528
Cdd:pfam05088 1335 RWLLRNRRQPLDIAATIARFAPGVAALAAQLPELLPGAEREALQARAARLVEAGVPEELARRVAGLPYLYSALDIVEVAE 1414

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1529 RTGKEPLDVAEIYYDLADRLNITQLMDRIIELPRADRWQSMARASIREDLYAAHAALTADVLAVGNGTSTPEQRFKAWEQ 1608
Cdd:pfam05088 1415 ATGRDLEEVARVYFALGDRLGLDWLREQISALPVDNRWQALARAALRDDLYAQQRALTASVLASSDPDGDAEARVAAWLE 1494

                         1530      1540      1550
                   ....*....|....*....|....*....|....*.
gi 1903834682 1609 KNAAILSRARTTLDEIRSSDSFDLANLSVAMRTMRT 1644
Cdd:pfam05088 1495 ANAAALERWRAMLAEIRASSGLDLAMLSVALRELRD 1530
PTZ00324 PTZ00324
glutamate dehydrogenase 2; Provisional
 717-1231 1.06e-22

glutamate dehydrogenase 2; Provisional


Pssm-ID: 240359 [Multi-domain]  Cd Length: 1002  Bit Score: 106.04  E-value: 1.06e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  717 TFSQDYMEDTLRNNVHTTRLLVSLFEARMSPDRQQAGLEITDalleELDAALEQVASLDEDRILRSFLTVIKATLRTNFF 796
Cdd:PTZ00324   375 VFSERYIGEAIALYPEFVKLLYEDFRLGHTPERRAAITQKIE----ETARLKEDIRNELDRTIFSAFLSFNEHILKTNFY 450

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  797 QealggQPHDYVSMKFDPQAIPDLPAPRPAYEIW-VYSPRVEGVHLRFGKVARGGLRW--SDRREDFRT-------EILG 866
Cdd:PTZ00324   451 K-----TEKTALAFRLDPSFLSELEYPRVPYGVFlVAGAQFRGFHIRFTDIARGGVRMiqSFKEQAYRRnkrsvfdENYN 525

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  867 LVKAQMVKNTVIVPVGAKGGFvakqLPDPGVDRDAWLAEGVASYKTFISALLDItdnmvageVVPPQDVVRHDGDDTYLV 946
Cdd:PTZ00324   526 LASTQLLKNKDIPEGGSKGTI----LLSSRYLNKFAQVRCQHAFLQYIDALLDV--------MLPGEKVVDHLKQEEIIF 593

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682  947 VAADK-GTATFSDIANEVANTYNFWLGDAFASGGS---AGYDHKGMGITARGAWESVKRHFRELGVDtqSEDFTVVGIGD 1022
Cdd:PTZ00324   594 LGPDEhTTGTLMDWAALHAKKRGYPFWKSFTTGKSpsmGGIPHDTYGMTTRSVRAYVTGILEKLGLN--EEEVTKFQTGG 671

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1023 MSGDVFGNGMLLSEHiRLVAAFDHRHIFIDPTpdaAVSYAERRRLFElPRSSWADYNTDLLSAGGGIFPRTAKSI--PLN 1100
Cdd:PTZ00324   672 PDGDLGSNELLLSKE-KTVGIVDGSGVLHDPE---GLNREELRRLAH-HRLPAREFDESKLSPQGFLVLTDDRDVklPDG 746

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1903834682 1101 SHIREALGIEGK--VTKMTPADLMktilkAPVdllwnGGigtyvKASSESNADVGDKANDAirvdGADLRVKVVGEGGNL 1178
Cdd:PTZ00324   747 TIVESGLRFRNEfhLLPYSDADVF-----VPC-----GG-----RPRSVTLFNVGRFFDEK----NGKLRFKIIVEGANL 807

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1903834682 1179 GLTQLGRIEFALHGGRINTDAIDNSAGVDTSDHEVnikilLNGLVADGD-----MTVK 1231
Cdd:PTZ00324   808 FITQDARLALEECGVILFKDASANKGGVTSSSLEV-----LAALALSDEefaehMCVK 860
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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