|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11302 |
PRK11302 |
DNA-binding transcriptional regulator HexR; Provisional |
1-280 |
0e+00 |
|
DNA-binding transcriptional regulator HexR; Provisional
Pssm-ID: 183082 [Multi-domain] Cd Length: 284 Bit Score: 584.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 1 MNTLEKIQANLDQLSKSERKVAEVILAAPQTAIHSSIATLAKMADVSEPTVNRFCRRLETKGFPDFKLHLAQSLANGTPY 80
Cdd:PRK11302 1 MNMLEKIQSRLEHLSKSERKVAEVILASPQTAIHSSIATLAKMANVSEPTVNRFCRSLDTKGFPDFKLHLAQSLANGTPY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 81 VNRNVEESDSVDAYTSKIFESAMAGLEMAKNHLDMATINRAVDLLTQAKKISFFGLGASAAVAHDAMNKFFRFNIPVVYF 160
Cdd:PRK11302 81 VNRNVEEDDSVEAYTGKIFESAMASLDHARQSLDPSAINRAVDLLTQAKKISFFGLGASAAVAHDAQNKFFRFNVPVVYF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 161 DDIVMQRMSCMNSNEGDVVVLISHTGRTKSLVEMAHLARENDATVIAITSRDTPLALEASLALLLDVPEDTDVYMPMVSR 240
Cdd:PRK11302 161 DDIVMQRMSCMNSSDGDVVVLISHTGRTKSLVELAQLARENGATVIAITSAGSPLAREATLALTLDVPEDTDIYMPMVSR 240
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1391979082 241 LAQLTLVDALATGFTLRRGAKFRDNLKRVKEALKESRFDK 280
Cdd:PRK11302 241 IAQLTVIDVLATGFTLRRGAKFRDNLKRVKEALKESRFDK 280
|
|
| RpiR |
COG1737 |
DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains ... |
1-278 |
6.29e-91 |
|
DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains [Transcription];
Pssm-ID: 441343 [Multi-domain] Cd Length: 286 Bit Score: 271.42 E-value: 6.29e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 1 MNTLEKIQANLDQLSKSERKVAEVILAAPQTAIHSSIATLAKMADVSEPTVNRFCRRLETKGFPDFKLHLAQSLANGTPY 80
Cdd:COG1737 5 MSLLERIRARYPSLSPSERRIADYILDNPEEVAFMSIAELAEAAGVSEATVVRFCRKLGFSGFPELKLALAQELAEGLSS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 81 VNR--NVEESDSVDAYTSKIFESAMAGLEMAKNHLDMATINRAVDLLTQAKKISFFGLGASAAVAHDAMNKFFRFNIPVV 158
Cdd:COG1737 85 YERlrRLSPDDSLEDILAKVLEAEIANLEETLELLDEEALERAVDLLAKARRIYIFGVGASAPVAEDLAYKLLRLGKNVV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 159 YFD-DIVMQRMSCMNSNEGDVVVLISHTGRTKSLVEMAHLARENDATVIAIT-SRDTPLALEASLALLLDVPEDTDVYMP 236
Cdd:COG1737 165 LLDgDGHLQAESAALLGPGDVVIAISFSGYTRETLEAARLAKERGAKVIAITdSPLSPLAKLADVVLYVPSEEPTLRSSA 244
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1391979082 237 MVSRLAQLTLVDALATGFTLRRGAKFRDNLKRVKEALKESRF 278
Cdd:COG1737 245 FSSRVAQLALIDALAAAVAQRDGDKARERLERTEALLSELRE 286
|
|
| SIS_RpiR |
cd05013 |
RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many ... |
116-253 |
1.59e-39 |
|
RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate isomerases that catalyze the reversible reactions of ribose 5-phosphate into ribulose 5-phosphate.
Pssm-ID: 240144 [Multi-domain] Cd Length: 139 Bit Score: 134.66 E-value: 1.59e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 116 ATINRAVDLLTQAKKISFFGLGASAAVAHDAMNKFFRFNIPVVYFDDIVMQRMSCMNSNEGDVVVLISHTGRTKSLVEMA 195
Cdd:cd05013 1 EALEKAVDLLAKARRIYIFGVGSSGLVAEYLAYKLLRLGKPVVLLSDPHLQLMSAANLTPGDVVIAISFSGETKETVEAA 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1391979082 196 HLARENDATVIAITSR-DTPLALEASLALLLDVPEDTDVYMPMVSRLAQLTLVDALATG 253
Cdd:cd05013 81 EIAKERGAKVIAITDSaNSPLAKLADIVLLVSSEEGDFRSSAFSSRIAQLALIDALFLA 139
|
|
| HTH_6 |
pfam01418 |
Helix-turn-helix domain, rpiR family; This domain contains a helix-turn-helix motif. The best ... |
1-77 |
3.72e-30 |
|
Helix-turn-helix domain, rpiR family; This domain contains a helix-turn-helix motif. The best characterized member of this family is Swiss:P39266. RpiR is a regulator of the expression of rpiB gene.
Pssm-ID: 334531 [Multi-domain] Cd Length: 77 Bit Score: 108.57 E-value: 3.72e-30
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1391979082 1 MNTLEKIQANLDQLSKSERKVAEVILAAPQTAIHSSIATLAKMADVSEPTVNRFCRRLETKGFPDFKLHLAQSLANG 77
Cdd:pfam01418 1 MGLLEKIQSRYSKLTKSERKIADYILAHPDLAIHLSISAIAKAAGVSEATIVRFCQKLGFSGFPELKLALAGELANS 77
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11302 |
PRK11302 |
DNA-binding transcriptional regulator HexR; Provisional |
1-280 |
0e+00 |
|
DNA-binding transcriptional regulator HexR; Provisional
Pssm-ID: 183082 [Multi-domain] Cd Length: 284 Bit Score: 584.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 1 MNTLEKIQANLDQLSKSERKVAEVILAAPQTAIHSSIATLAKMADVSEPTVNRFCRRLETKGFPDFKLHLAQSLANGTPY 80
Cdd:PRK11302 1 MNMLEKIQSRLEHLSKSERKVAEVILASPQTAIHSSIATLAKMANVSEPTVNRFCRSLDTKGFPDFKLHLAQSLANGTPY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 81 VNRNVEESDSVDAYTSKIFESAMAGLEMAKNHLDMATINRAVDLLTQAKKISFFGLGASAAVAHDAMNKFFRFNIPVVYF 160
Cdd:PRK11302 81 VNRNVEEDDSVEAYTGKIFESAMASLDHARQSLDPSAINRAVDLLTQAKKISFFGLGASAAVAHDAQNKFFRFNVPVVYF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 161 DDIVMQRMSCMNSNEGDVVVLISHTGRTKSLVEMAHLARENDATVIAITSRDTPLALEASLALLLDVPEDTDVYMPMVSR 240
Cdd:PRK11302 161 DDIVMQRMSCMNSSDGDVVVLISHTGRTKSLVELAQLARENGATVIAITSAGSPLAREATLALTLDVPEDTDIYMPMVSR 240
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1391979082 241 LAQLTLVDALATGFTLRRGAKFRDNLKRVKEALKESRFDK 280
Cdd:PRK11302 241 IAQLTVIDVLATGFTLRRGAKFRDNLKRVKEALKESRFDK 280
|
|
| RpiR |
COG1737 |
DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains ... |
1-278 |
6.29e-91 |
|
DNA-binding transcriptional regulator, MurR/RpiR family, contains HTH and SIS domains [Transcription];
Pssm-ID: 441343 [Multi-domain] Cd Length: 286 Bit Score: 271.42 E-value: 6.29e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 1 MNTLEKIQANLDQLSKSERKVAEVILAAPQTAIHSSIATLAKMADVSEPTVNRFCRRLETKGFPDFKLHLAQSLANGTPY 80
Cdd:COG1737 5 MSLLERIRARYPSLSPSERRIADYILDNPEEVAFMSIAELAEAAGVSEATVVRFCRKLGFSGFPELKLALAQELAEGLSS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 81 VNR--NVEESDSVDAYTSKIFESAMAGLEMAKNHLDMATINRAVDLLTQAKKISFFGLGASAAVAHDAMNKFFRFNIPVV 158
Cdd:COG1737 85 YERlrRLSPDDSLEDILAKVLEAEIANLEETLELLDEEALERAVDLLAKARRIYIFGVGASAPVAEDLAYKLLRLGKNVV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 159 YFD-DIVMQRMSCMNSNEGDVVVLISHTGRTKSLVEMAHLARENDATVIAIT-SRDTPLALEASLALLLDVPEDTDVYMP 236
Cdd:COG1737 165 LLDgDGHLQAESAALLGPGDVVIAISFSGYTRETLEAARLAKERGAKVIAITdSPLSPLAKLADVVLYVPSEEPTLRSSA 244
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 1391979082 237 MVSRLAQLTLVDALATGFTLRRGAKFRDNLKRVKEALKESRF 278
Cdd:COG1737 245 FSSRVAQLALIDALAAAVAQRDGDKARERLERTEALLSELRE 286
|
|
| PRK14101 |
PRK14101 |
bifunctional transcriptional regulator/glucokinase; |
4-260 |
8.47e-64 |
|
bifunctional transcriptional regulator/glucokinase;
Pssm-ID: 184507 [Multi-domain] Cd Length: 638 Bit Score: 211.31 E-value: 8.47e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 4 LEKIQANLDQLSKSERKVAEVILAAPQTAIHSSIATLAKMADVSEPTVNRFCRRLETKGFPDFKLHLAQSLANGTPYVNR 83
Cdd:PRK14101 344 FERIRQMRDALTPAERRVADLALNHPRSIINDPIVDIARKADVSQPTVIRFCRSLGCQGLSDFKLKLATGLTGTIPMSHS 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 84 NVEESDSVDAYTSKIFESAMAGLEMAKNHLDMATINRAVDLLTQAKKISFFGLGASAAVAHDAMNKFFRFNIPVVYFDDI 163
Cdd:PRK14101 424 QVHLGDTATDFGAKVLDNTVSAILQLREHLNFEHVEQAIDILNNARRIEFYGLGNSNIVAQDAHYKFFRFGIPTIAYGDL 503
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 164 VMQRMSCMNSNEGDVVVLISHTGRTKSLVEMAHLARENDATVIAITSRDTPLALEASLALLLDVPEDTDVYMPMVSRLAQ 243
Cdd:PRK14101 504 YMQAASAALLGKGDVIVAVSKSGRAPELLRVLDVAMQAGAKVIAITSSNTPLAKRATVALETDHIEMRESQLSMISRILH 583
|
250
....*....|....*..
gi 1391979082 244 LTLVDALATGFTLRRGA 260
Cdd:PRK14101 584 LVMIDILAVGVAIRRAA 600
|
|
| PRK11337 |
PRK11337 |
MurR/RpiR family transcriptional regulator; |
7-277 |
2.98e-42 |
|
MurR/RpiR family transcriptional regulator;
Pssm-ID: 183089 [Multi-domain] Cd Length: 292 Bit Score: 146.83 E-value: 2.98e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 7 IQANLDQLSKSERKVAEVILAAPQTAIHSSIATLAKMADVSEPTVNRFCRRLETKGFPDFKLHLAQSLANGTPYVNRNVE 86
Cdd:PRK11337 19 IRMKQEGLTPLESRVVEWLLKPGDLSEATALKDIAEALAVSEAMIVKVAKKLGFSGFRNLRSALEDYFSQSEQVLHSELS 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 87 ESDSVDAYTSKIFESAMAGLEMAKNHLDMATINRAVDLLTQAKKISFFGLGASAAVAHDAMNKFFRFNIPVVYFDDIVMQ 166
Cdd:PRK11337 99 FDDAPQDVVNKVFNTSLQAIEETQSILDVDEFHRAARFFYQARQRDLYGAGGSAAIARDVQHKFLRIGVRCQAYDDAHIM 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 167 RMSCMNSNEGDVVVLISHTGRTKSLVEMAHLARENDATVIAITSRDT-PLALEASLALLLDVPEDTDVYMPMVSRLAQLT 245
Cdd:PRK11337 179 LMSAALLQEGDVVLVVSHSGRTSDVIEAVELAKKNGAKIICITNSYHsPIAKLADYVICSTAQGSPLLGENAAARIAQLN 258
|
250 260 270
....*....|....*....|....*....|..
gi 1391979082 246 LVDALATGFTLRRGAKFRDNLKRVKEALKESR 277
Cdd:PRK11337 259 ILDAFFVSVAQLNIEQAEINLQKTGAAVDFFR 290
|
|
| SIS_RpiR |
cd05013 |
RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many ... |
116-253 |
1.59e-39 |
|
RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate isomerases that catalyze the reversible reactions of ribose 5-phosphate into ribulose 5-phosphate.
Pssm-ID: 240144 [Multi-domain] Cd Length: 139 Bit Score: 134.66 E-value: 1.59e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 116 ATINRAVDLLTQAKKISFFGLGASAAVAHDAMNKFFRFNIPVVYFDDIVMQRMSCMNSNEGDVVVLISHTGRTKSLVEMA 195
Cdd:cd05013 1 EALEKAVDLLAKARRIYIFGVGSSGLVAEYLAYKLLRLGKPVVLLSDPHLQLMSAANLTPGDVVIAISFSGETKETVEAA 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1391979082 196 HLARENDATVIAITSR-DTPLALEASLALLLDVPEDTDVYMPMVSRLAQLTLVDALATG 253
Cdd:cd05013 81 EIAKERGAKVIAITDSaNSPLAKLADIVLLVSSEEGDFRSSAFSSRIAQLALIDALFLA 139
|
|
| HTH_6 |
pfam01418 |
Helix-turn-helix domain, rpiR family; This domain contains a helix-turn-helix motif. The best ... |
1-77 |
3.72e-30 |
|
Helix-turn-helix domain, rpiR family; This domain contains a helix-turn-helix motif. The best characterized member of this family is Swiss:P39266. RpiR is a regulator of the expression of rpiB gene.
Pssm-ID: 334531 [Multi-domain] Cd Length: 77 Bit Score: 108.57 E-value: 3.72e-30
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1391979082 1 MNTLEKIQANLDQLSKSERKVAEVILAAPQTAIHSSIATLAKMADVSEPTVNRFCRRLETKGFPDFKLHLAQSLANG 77
Cdd:pfam01418 1 MGLLEKIQSRYSKLTKSERKIADYILAHPDLAIHLSISAIAKAAGVSEATIVRFCQKLGFSGFPELKLALAGELANS 77
|
|
| PRK15482 |
PRK15482 |
HTH-type transcriptional regulator MurR; |
1-254 |
2.70e-22 |
|
HTH-type transcriptional regulator MurR;
Pssm-ID: 185379 [Multi-domain] Cd Length: 285 Bit Score: 93.61 E-value: 2.70e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 1 MNTLEKIQANLDQLSKSERKVAEVILAAPQTAIHSSIATLAKMADVSEPTVNRFCRRLETKGFPDFKLHLAQSLA----- 75
Cdd:PRK15482 1 MLYLTKIRNAESEFTENEQKIADFLRANVSELKSVSSRKMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSasrek 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 76 -NGTP-YVNRNVEESDSVDAYTSKIFESAMAGLEMAKNHLDMATINRAVDLLTQAKKISFFGLGASAAVAHDAMNKFFRF 153
Cdd:PRK15482 81 tNATAlHLHSSITSDDSLEVIARKLNREKELALEQTCALFDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 154 NIPVVYFDDIVMQRMSCMNSNEGDVVVLISHTGRTKSLVEMAHLARENDATVIAITS-RDTPLALEASLALLLDVPEDTD 232
Cdd:PRK15482 161 GYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSlADSPLRRLAHFTLDTVSGETEW 240
|
250 260
....*....|....*....|..
gi 1391979082 233 VYMPMVSRLAQLTLVDALATGF 254
Cdd:PRK15482 241 RSSSMSTRTAQNSVTDLLFVGL 262
|
|
| SIS |
pfam01380 |
SIS domain; SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and ... |
124-252 |
4.15e-20 |
|
SIS domain; SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars. Presumably the SIS domains bind to the end-product of the pathway.
Pssm-ID: 426230 [Multi-domain] Cd Length: 131 Bit Score: 83.89 E-value: 4.15e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 124 LLTQAKKISFFGLGASAAVAHDAMNKFFRFNIPVVYFDDIVMQRMS-CMNSNEGDVVVLISHTGRTKSLVEMAHLAREND 202
Cdd:pfam01380 1 LLAKAKRIFVIGRGTSYAIALELALKFEEIGYKVVEVELASELRHGvLALVDEDDLVIAISYSGETKDLLAAAELAKARG 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1391979082 203 ATVIAITSR-DTPLALEASLALLLDVPEDTDVyMPMVSRLAQLTLVDALAT 252
Cdd:pfam01380 81 AKIIAITDSpGSPLAREADHVLYINAGPETGV-ASTKSITAQLAALDALAV 130
|
|
| COG4821 |
COG4821 |
Uncharacterized conserved protein, contains SIS (Sugar ISomerase) phosphosugar binding domain ... |
100-212 |
8.14e-10 |
|
Uncharacterized conserved protein, contains SIS (Sugar ISomerase) phosphosugar binding domain [General function prediction only];
Pssm-ID: 443849 [Multi-domain] Cd Length: 250 Bit Score: 57.90 E-value: 8.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 100 ESAMAGLEMAKNHLD------MATINRAVDLLTQAKK----ISFFGLGASAAVAHDAmnkFFR------FN-I---PVVY 159
Cdd:COG4821 3 DLASQYLDEVRELLDrieetqAEAIEKAADLIADSIAagglVHLFGTGHSHLLAEEV---FYRagglvgFNpIldpSLML 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1391979082 160 FDDIVMQRMS---------------CMNSNEGDVVVLISHTGRTKSLVEMAHLARENDATVIAITSRD 212
Cdd:COG4821 80 HNGAPGVLQSsflervegyaeiileNYPIRPGDVLIVISNSGRNAVPIEMALEAKERGLKVIAITSLE 147
|
|
| SIS_PHI |
cd05005 |
Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) ... |
94-210 |
2.64e-08 |
|
Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with formadelhyde to become hexulose-6-phosphate, which is then isomerized to fructose-6-phosphate by PHI.
Pssm-ID: 240138 [Multi-domain] Cd Length: 179 Bit Score: 52.58 E-value: 2.64e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 94 YTSKIFESamagLEMAKNHLDMATINRAVDLLTQAKKISFFGLGASAAVAhdamnKFF--R-----FNIPVVyfDDIVMQ 166
Cdd:cd05005 3 YLSLILEE----IENVADKIDEEELDKLISAILNAKRIFVYGAGRSGLVA-----KAFamRlmhlgLNVYVV--GETTTP 71
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1391979082 167 RMScmnsnEGDVVVLISHTGRTKSLVEMAHLARENDATVIAITS 210
Cdd:cd05005 72 AIG-----PGDLLIAISGSGETSSVVNAAEKAKKAGAKVVLITS 110
|
|
| SIS_2 |
pfam13580 |
SIS domain; SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and ... |
114-210 |
3.55e-08 |
|
SIS domain; SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Pssm-ID: 433326 [Multi-domain] Cd Length: 138 Bit Score: 51.44 E-value: 3.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 114 DMATINRAVDLLTQA----KKISFFGLGASAAVAHDAMN---KFFRFNIP----VVYFDDIVMQRMSCM----------- 171
Cdd:pfam13580 17 QADAIEKAADLIAASlangGKVYAFGTGHSAAPAEELFAragGLAGFEPIllpaLALHTDASATISTALerdegyarqil 96
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1391979082 172 ---NSNEGDVVVLISHTGRTKSLVEMAHLARENDATVIAITS 210
Cdd:pfam13580 97 alyPGRPGDVLIVISNSGINAVPVEAALEAKERGMKVIALTS 138
|
|
| SIS_GmhA |
cd05006 |
Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose ... |
101-212 |
1.00e-07 |
|
Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of gram-negative bacteria inner core lipopolysaccharide precursor, L-glycero-D-mannoheptose (Gmh).
Pssm-ID: 240139 [Multi-domain] Cd Length: 177 Bit Score: 50.97 E-value: 1.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 101 SAMAGLEMAKNHLDMATINRAVDLLTQA----KKISFFGLGASAAVA-HDA--MNKFFRFN---IPVVYFDDIVMQRMSC 170
Cdd:cd05006 2 QESIQLKEALLELLAEAIEQAAQLLAEAllngGKILICGNGGSAADAqHFAaeLVKRFEKErpgLPAIALTTDTSILTAI 81
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1391979082 171 MN---------------SNEGDVVVLISHTGRTKSLVEMAHLARENDATVIAITSRD 212
Cdd:cd05006 82 ANdygyeevfsrqvealGQPGDVLIGISTSGNSPNVLKALEAAKERGMKTIALTGRD 138
|
|
| SIS_Kpsf |
cd05014 |
KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ... |
175-251 |
3.01e-07 |
|
KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose 5-phosphate to arabinose 5-phosphate. This is the second step in the CMP-Kdo biosynthesis pathway.
Pssm-ID: 240145 [Multi-domain] Cd Length: 128 Bit Score: 48.31 E-value: 3.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 175 EGDVVVLISHTGRTKSLVEMAHLARENDATVIAITS-RDTPLALEASLALLLDVPEDTDVY--MPMVSRLAQLTLVDALA 251
Cdd:cd05014 47 PGDVVIAISNSGETDELLNLLPHLKRRGAPIIAITGnPNSTLAKLSDVVLDLPVEEEACPLglAPTTSTTAMLALGDALA 126
|
|
| SIS |
cd04795 |
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and ... |
131-209 |
5.37e-07 |
|
SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Pssm-ID: 240112 [Multi-domain] Cd Length: 87 Bit Score: 46.60 E-value: 5.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 131 ISFFGLGASAAVAHDAMNKFFRFN--IPVVYFDDIVMQRMSCMNSNEGDVVVLISHTGRTKSLVEMAHLARENDATVIAI 208
Cdd:cd04795 1 IFVIGIGGSGAIAAYFALELLELTgiEVVALIATELEHASLLSLLRKGDVVIALSYSGRTEELLAALEIAKELGIPVIAI 80
|
.
gi 1391979082 209 T 209
Cdd:cd04795 81 T 81
|
|
| PRK02947 |
PRK02947 |
sugar isomerase domain-containing protein; |
175-212 |
5.78e-07 |
|
sugar isomerase domain-containing protein;
Pssm-ID: 179510 [Multi-domain] Cd Length: 246 Bit Score: 49.48 E-value: 5.78e-07
10 20 30
....*....|....*....|....*....|....*...
gi 1391979082 175 EGDVVVLISHTGRTKSLVEMAHLARENDATVIAITSRD 212
Cdd:PRK02947 106 PGDVLIVVSNSGRNPVPIEMALEAKERGAKVIAVTSLA 143
|
|
| SIS_1 |
cd05710 |
A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar ... |
174-214 |
2.09e-05 |
|
A subgroup of the SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars.
Pssm-ID: 240214 [Multi-domain] Cd Length: 120 Bit Score: 42.95 E-value: 2.09e-05
10 20 30 40
....*....|....*....|....*....|....*....|..
gi 1391979082 174 NEGDVVVLISHTGRTKSLVEMAHLARENDATVIAIT-SRDTP 214
Cdd:cd05710 46 TEKSVVILASHSGNTKETVAAAKFAKEKGATVIGLTdDEDSP 87
|
|
| PRK08674 |
PRK08674 |
bifunctional phosphoglucose/phosphomannose isomerase; Validated |
107-210 |
2.35e-04 |
|
bifunctional phosphoglucose/phosphomannose isomerase; Validated
Pssm-ID: 181536 [Multi-domain] Cd Length: 337 Bit Score: 41.89 E-value: 2.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 107 EMAKNHLDMATINRAVDLLTQAKKISFFGLGASAAVAhDAMNKFFR--FNIPVVYFDDIVMQRMScmnsNEGDVVVLISH 184
Cdd:PRK08674 13 EQFEEALEIAISLDLEEDLEKIDNIVISGMGGSGIGG-DLLRILLFdeLKVPVFVNRDYTLPAFV----DEKTLVIAVSY 87
|
90 100
....*....|....*....|....*.
gi 1391979082 185 TGRTKSLVEMAHLARENDATVIAITS 210
Cdd:PRK08674 88 SGNTEETLSAVEQALKRGAKIIAITS 113
|
|
| GutQ |
COG0794 |
D-arabinose 5-phosphate isomerase GutQ [Carbohydrate transport and metabolism, Cell wall ... |
175-255 |
2.52e-04 |
|
D-arabinose 5-phosphate isomerase GutQ [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440557 [Multi-domain] Cd Length: 317 Bit Score: 41.89 E-value: 2.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 175 EGDVVVLISHTGRTKSLVEMAHLARENDATVIAITSR-------------DTPlaleaslallldVPEDTDVY--MPMVS 239
Cdd:COG0794 91 PGDVVIAISNSGETEELLALLPLLKRLGVPLIAITGNpdstlaraadvvlDLP------------VEREACPLnlAPTTS 158
|
90 100
....*....|....*....|..
gi 1391979082 240 RLAQLTLVDALA------TGFT 255
Cdd:COG0794 159 TTATLALGDALAvalleaRGFT 180
|
|
| SIS_PGI_PMI_1 |
cd05017 |
The members of this protein family contain the SIS (Sugar ISomerase) domain and have both the ... |
130-210 |
6.88e-04 |
|
The members of this protein family contain the SIS (Sugar ISomerase) domain and have both the phosphoglucose isomerase (PGI) and the phosphomannose isomerase (PMI) functions. These functions catalyze the reversible reactions of glucose 6-phosphate to fructose 6-phosphate, and mannose 6-phosphate to fructose 6-phosphate, respectively at an equal rate. This protein contains two SIS domains. This alignment is based on the first SIS domain.
Pssm-ID: 240148 [Multi-domain] Cd Length: 119 Bit Score: 38.79 E-value: 6.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1391979082 130 KISFFGLGASAAVAhDAMNKFF--RFNIPVVYFDDIVMQRMScmnsNEGDVVVLISHTGRTKSLVEMAHLARENDATVIA 207
Cdd:cd05017 1 NIVILGMGGSGIGG-DLLESLLldEAKIPVYVVKDYTLPAFV----DRKTLVIAVSYSGNTEETLSAVEQAKERGAKIVA 75
|
...
gi 1391979082 208 ITS 210
Cdd:cd05017 76 ITS 78
|
|
| SIS_GlmS_GlmD_1 |
cd05008 |
SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and ... |
174-209 |
7.59e-04 |
|
SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal glutaminase domain and two C-terminal SIS domains and catalyzes the first step in hexosamine metabolism, converting fructose 6-phosphate into glucosamine 6-phosphate using glutamine as nitrogen source. The glutaminase domain hydrolyzes glutamine to glutamate and ammonia. Ammonia is transferred through a channel to the isomerase domain for glucosamine 6-phosphate synthesis. The end product of the pathway is N-acetylglucosamine, which plays multiple roles in eukaryotic cells including being a building block of bacterial and fungal cell walls. In the absence of glutamine, GlmS catalyzes the isomerization of fructose 6-phosphate into glucose 6- phosphate (PGI-like activity). Glucosamine-6-phosphate deaminase (GlmD) contains two SIS domains and catalyzes the deamination and isomerization of glucosamine-6-phosphate into fructose-6-phosphate with the release of ammonia; in presence of high ammonia concentration, GlmD can catalyze the reverse reaction.
Pssm-ID: 240141 [Multi-domain] Cd Length: 126 Bit Score: 38.63 E-value: 7.59e-04
10 20 30
....*....|....*....|....*....|....*.
gi 1391979082 174 NEGDVVVLISHTGRTKSLVEMAHLARENDATVIAIT 209
Cdd:cd05008 45 DEDTLVIAISQSGETADTLAALRLAKEKGAKTVAIT 80
|
|
| PRK13936 |
PRK13936 |
phosphoheptose isomerase; Provisional |
174-212 |
7.89e-03 |
|
phosphoheptose isomerase; Provisional
Pssm-ID: 237567 Cd Length: 197 Bit Score: 36.56 E-value: 7.89e-03
10 20 30
....*....|....*....|....*....|....*....
gi 1391979082 174 NEGDVVVLISHTGRTKSLVEMAHLARENDATVIAITSRD 212
Cdd:PRK13936 110 QPGDVLLAISTSGNSANVIQAIQAAHEREMHVVALTGRD 148
|
|
| |
