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Conserved domains on  [gi|613387800|gb|EZZ91722|]
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hypothetical protein W395_02204 [Staphylococcus aureus VET0057R]

Protein Classification

methionine ABC transporter permease( domain architecture ID 10005172)

methionine ABC transporter permease is the transmembrane (TM) subunit of the ABC transporter complex, such as MetNPQ, that is involved in methionine import, and is responsible for the translocation of the substrate across the membrane

EC:  7.4.2.11
Gene Ontology:  GO:0033232|GO:0048473|GO:0042626
PubMed:  22095702|11421270|25750732|24638992
TCDB:  3.A.1.24

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 12-231 1.44e-72

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 441614  Cd Length: 220  Bit Score: 219.93  E-value: 1.44e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  12 MITMPNIQWPEVWTAIVETLYMTVVSTIFTFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIP 91
Cdd:COG2011    1 MLTMWSELWPLLLQATGETLYMVGVSTLIAVLLGLPLGVLLVLTRPGGLLPNPVLYRVLGVIVNIFRSIPFIILLVALIP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  92 FTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIAL 171
Cdd:COG2011   81 LTRLIVGTSIGTTAAIVPLTIAAIPFFARLVENALREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTVTLISL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800 172 VGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR 231
Cdd:COG2011  161 IGYSAMAGAVGGGGLGDLAIRYGYQRFDTDVMLVTVVILIVLVQIIQFLGDRLARRLDHR 220
 
Name Accession Description Interval E-value
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 12-231 1.44e-72

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 219.93  E-value: 1.44e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  12 MITMPNIQWPEVWTAIVETLYMTVVSTIFTFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIP 91
Cdd:COG2011    1 MLTMWSELWPLLLQATGETLYMVGVSTLIAVLLGLPLGVLLVLTRPGGLLPNPVLYRVLGVIVNIFRSIPFIILLVALIP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  92 FTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIAL 171
Cdd:COG2011   81 LTRLIVGTSIGTTAAIVPLTIAAIPFFARLVENALREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTVTLISL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800 172 VGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR 231
Cdd:COG2011  161 IGYSAMAGAVGGGGLGDLAIRYGYQRFDTDVMLVTVVILIVLVQIIQFLGDRLARRLDHR 220
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
29-196 2.21e-33

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 119.84  E-value: 2.21e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  29 ETLYMTVVSTIFTFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALP 108
Cdd:PRK10782  15 ETLAMTFVSGFFGFVIGLPVGVLLYVTRPGQIIANAKLYRTLSALVNIFRSIPFIILLVWMIPFTRVIVGTSIGLQAAIV 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800 109 ALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGN 188
Cdd:PRK10782  95 PLTVGAAPFIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGYSAMGGAVGAGGLGQ 174


                 ....*...
gi 613387800 189 LAYLTGFT 196
Cdd:PRK10782 175 IGYQYGYI 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 64-193 4.68e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 56.90  E-value: 4.68e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  64 RLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGA---APFYARLVEIAFKEIDKGVIEAAWSM 140
Cdd:cd06261   31 GKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALILALlliAPFARLIRRAALESIPKDLVEAARAL 110

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 613387800 141 GANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLT 193
Cdd:cd06261  111 GASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGTGL 163
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 4-187 1.32e-08

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 53.70  E-value: 1.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800    4 SFSEIINEMITmPNI-QWPEVWTAIVETLYMTVVSTIFtfiLGLILGVLLFLSAKGKSIGaRLFYSIVSFIVNLFRAIpf 82
Cdd:TIGR01097  37 QMADLLGRMFP-PDWsYLPRILKALLETLAMAILGTVL---AAVLAVPLALLAARNITPS-PWLYGLARLLLNFLRAI-- 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800   83 iililllipfTSLILGTI-------SGPTGALpALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPE 155
Cdd:TIGR01097 110 ----------PELVWALIfvaavglGPFAGVL-ALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQ 178

                         170       180       190
                  ....*....|....*....|....*....|...
gi 613387800  156 AMPALVSgITVTAIAL-VGSTAVAGVIGAGGLG 187
Cdd:TIGR01097 179 VLPQFLS-YTLYRFEInVRAAAVLGLVGAGGIG 210
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 101-231 1.32e-07

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 49.99  E-value: 1.32e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  101 SGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGV 180
Cdd:pfam00528  50 HGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEF 129

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 613387800  181 IGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR 231
Cdd:pfam00528 130 LGSWPGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPR 180
 
Name Accession Description Interval E-value
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 12-231 1.44e-72

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 219.93  E-value: 1.44e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  12 MITMPNIQWPEVWTAIVETLYMTVVSTIFTFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIP 91
Cdd:COG2011    1 MLTMWSELWPLLLQATGETLYMVGVSTLIAVLLGLPLGVLLVLTRPGGLLPNPVLYRVLGVIVNIFRSIPFIILLVALIP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  92 FTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIAL 171
Cdd:COG2011   81 LTRLIVGTSIGTTAAIVPLTIAAIPFFARLVENALREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTVTLISL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800 172 VGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR 231
Cdd:COG2011  161 IGYSAMAGAVGGGGLGDLAIRYGYQRFDTDVMLVTVVILIVLVQIIQFLGDRLARRLDHR 220
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
29-196 2.21e-33

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 119.84  E-value: 2.21e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  29 ETLYMTVVSTIFTFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALP 108
Cdd:PRK10782  15 ETLAMTFVSGFFGFVIGLPVGVLLYVTRPGQIIANAKLYRTLSALVNIFRSIPFIILLVWMIPFTRVIVGTSIGLQAAIV 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800 109 ALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGN 188
Cdd:PRK10782  95 PLTVGAAPFIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGYSAMGGAVGAGGLGQ 174


                 ....*...
gi 613387800 189 LAYLTGFT 196
Cdd:PRK10782 175 IGYQYGYI 182
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 95-205 2.79e-15

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 71.62  E-value: 2.79e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  95 LILGTisGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGS 174
Cdd:COG1174   76 PLLGI--GPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGT 153

                         90       100       110
                 ....*....|....*....|....*....|.
gi 613387800 175 TAVAGVIGAGGLGNLaYLTGFTRNQNDVILV 205
Cdd:COG1174  154 ATLAALIGAGGLGDL-IFDGLQLNNTALILA 183
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 103-167 2.02e-12

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 64.77  E-value: 2.02e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 613387800 103 PTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVT 167
Cdd:COG0555  136 PLGIVLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALA 200
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 5-187 4.13e-10

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 57.78  E-value: 4.13e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800   5 FSEIINEMITmPNI-QWPEVWTAIVETLYMTVVSTIFTFILGLILGVLlflSAKGKSiGARLFYSIVSFIVNLFRAIPfi 83
Cdd:COG3639   31 LADFLSRFFP-PDWsYLPDLLSALLETLAIALLGTLLGAVLALPLAFL---AARNLA-PNPWVRLLARRLLNVLRAIP-- 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  84 ililllipftSLILGTI------SGP-TGALpALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEA 156
Cdd:COG3639  104 ----------ELVWALIfvaavgLGPfAGVL-ALAIHTIGFLGKLFAEAIEEIDPGPVEALRATGASRLQVIRYGVLPQV 172

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 613387800 157 MPALVSgitvtaIAL------VGSTAVAGVIGAGGLG 187
Cdd:COG3639  173 LPQFLS------YTLyrfeinIRAATVLGLVGAGGIG 203
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 64-193 4.68e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 56.90  E-value: 4.68e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  64 RLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGA---APFYARLVEIAFKEIDKGVIEAAWSM 140
Cdd:cd06261   31 GKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGLGLPALILALlliAPFARLIRRAALESIPKDLVEAARAL 110

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 613387800 141 GANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLT 193
Cdd:cd06261  111 GASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPGTGL 163
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 102-163 4.44e-09

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 55.39  E-value: 4.44e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 613387800 102 GPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSG 163
Cdd:PRK15050 160 SPGGVILAEITFYTPFVVRPLLAAFAQLDARQLEAAASLGASPWRVARRVILPEAWPALAAG 221
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
100-184 7.17e-09

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 55.17  E-value: 7.17e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800 100 ISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAG 179
Cdd:COG1178  136 IYGLGGIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPL 215


                 ....*
gi 613387800 180 VIGAG 184
Cdd:COG1178  216 VLGGG 220
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 97-163 8.72e-09

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 54.35  E-value: 8.72e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 613387800  97 LGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSG 163
Cdd:COG1177  125 LGLSGGLWGLILAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAG 191
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 4-187 1.32e-08

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 53.70  E-value: 1.32e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800    4 SFSEIINEMITmPNI-QWPEVWTAIVETLYMTVVSTIFtfiLGLILGVLLFLSAKGKSIGaRLFYSIVSFIVNLFRAIpf 82
Cdd:TIGR01097  37 QMADLLGRMFP-PDWsYLPRILKALLETLAMAILGTVL---AAVLAVPLALLAARNITPS-PWLYGLARLLLNFLRAI-- 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800   83 iililllipfTSLILGTI-------SGPTGALpALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPE 155
Cdd:TIGR01097 110 ----------PELVWALIfvaavglGPFAGVL-ALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQ 178

                         170       180       190
                  ....*....|....*....|....*....|...
gi 613387800  156 AMPALVSgITVTAIAL-VGSTAVAGVIGAGGLG 187
Cdd:TIGR01097 179 VLPQFLS-YTLYRFEInVRAAAVLGLVGAGGIG 210
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 125-191 3.31e-08

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 52.84  E-value: 3.31e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800 125 AFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGG---LGNLAY 191
Cdd:COG1176  176 ALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKvlmIGNLIY 245
ProW COG4176
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 102-188 5.65e-08

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443335  Cd Length: 275  Bit Score: 52.02  E-value: 5.65e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800 102 GPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVT---AIALVgstAVA 178
Cdd:COG4176  153 GKVPGVIATVIFALPPAIRLTNLGIRQVPKELVEAADAFGATPWQLLFKVQLPLALPTIMAGVNQTimlALSMV---VIA 229

                         90
                 ....*....|
gi 613387800 179 GVIGAGGLGN 188
Cdd:COG4176  230 SMIGAGGLGQ 239
cysT CHL00187
sulfate transport protein; Provisional
 103-167 1.22e-07

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 50.78  E-value: 1.22e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 613387800 103 PTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVT 167
Cdd:CHL00187 137 KLGVLLAMIFVSFPFVVRTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLALT 201
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 101-231 1.32e-07

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 49.99  E-value: 1.32e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  101 SGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGV 180
Cdd:pfam00528  50 HGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEF 129

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 613387800  181 IGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR 231
Cdd:pfam00528 130 LGSWPGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPR 180
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 20-182 3.84e-07

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 48.92  E-value: 3.84e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  20 WPEVWTAIVETLYMTVVSTIFTFILGLILgvllflsAKGKSIGARLFYSIVSFIVNLFRAipfiililllipfTSLI--- 96
Cdd:COG0765   12 LPLLLEGLLVTLLLTVLAIVLGLVLGLLL-------ALARLSPNPVLRWLATAYVEFFRG-------------TPLLvql 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  97 ------LGTISGPTGALPALIIGAAPFY-ARLVEI---AFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITV 166
Cdd:COG0765   72 ffiyfgLPLLGIDLSPFVAAVIALTLNSaAYLAEIvraGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGN 151

                        170
                 ....*....|....*.
gi 613387800 167 TAIALVGSTAVAGVIG 182
Cdd:COG0765  152 EFISLLKDTSLVSVIG 167
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 125-205 4.10e-06

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 46.29  E-value: 4.10e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800 125 AFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVT-AIALVGSTAVAGVIGAGGLGNLAyLTGFTRNQNDVI 203
Cdd:COG0600  147 GVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIAlGLAWIGLVVAELLGASSGLGYLI-LDARQLLDTDLV 225


                 ..
gi 613387800 204 LV 205
Cdd:COG0600  226 FA 227
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
111-189 4.88e-06

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 46.62  E-value: 4.88e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 613387800 111 IIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNL 189
Cdd:PRK10952 216 IIFALPPIVRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQM 294
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 116-163 7.92e-06

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 45.36  E-value: 7.92e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 613387800 116 PFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSG 163
Cdd:PRK09500 140 PFVVVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVAAG 187
PRK15100 PRK15100
cystine ABC transporter permease;
107-181 2.74e-05

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 43.58  E-value: 2.74e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 613387800 107 LPALIIG----AAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVI 181
Cdd:PRK15100  88 IPAAMIGlslnTAAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSFISLVKDTSLAATI 166
PRK10971 PRK10971
sulfate/thiosulfate ABC transporter permease CysT;
109-167 5.92e-05

sulfate/thiosulfate ABC transporter permease CysT;


Pssm-ID: 182873  Cd Length: 277  Bit Score: 43.20  E-value: 5.92e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 613387800 109 ALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVT 167
Cdd:PRK10971 146 AMAFTSIPFVVRTVQPVLEELGPEYEEAAETLGATRWQSFRKVVLPELSPALLAGVALS 204
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 95-184 7.26e-04

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 39.71  E-value: 7.26e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  95 LILGTISGPTGALPALIIGAA--PFYARLVEIAFKEI-DKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIAL 171
Cdd:COG1173  131 IALVAVLGPGLLNVILALGLTgwPGYARLVRAQVLSLrEREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASA 210

                         90
                 ....*....|...
gi 613387800 172 VGSTAVAGVIGAG 184
Cdd:COG1173  211 ILAEAGLSFLGLG 223
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
104-163 1.04e-03

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 39.76  E-value: 1.04e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 613387800 104 TGALPALIIGAA----PFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSG 163
Cdd:COG1178  408 YGTLAILVLAYVvrflPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAA 471
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
21-199 2.21e-03

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 38.19  E-value: 2.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  21 PEVWTAIVETLYMTVVSTIFTFILGLILGVLLFLSAKGKSIgARLFY---SIVSFIV--NLFRAIPFIILILLLIPFTSL 95
Cdd:COG1175   72 PRFWNALGNTLLFTVVSVPLQLVLGLLLALLLNRKLRGRGF-FRTLFflpWVISPVVvaLIWKWLFNPDYGLLNALLGAL 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800  96 ILGTI---SGPTGALPALIIGA----APFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTA 168
Cdd:COG1175  151 GLEPInwlGDPSLALPAVIIVTvwkgTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLST 230

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 613387800 169 IALVGSTAVAGVIGAGG-------LGNLAYLTGFTRNQ 199
Cdd:COG1175  231 IGALQVFDLVYVLTGGGpgnstttLVLYIYQTAFQQFD 268
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 109-184 4.55e-03

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 37.36  E-value: 4.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613387800 109 ALIIGAA----PFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAG 184
Cdd:PRK09497 152 AVIIGLVyillPFMVLPLYSSIEKLDKPLLEAARDLGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMFYVSDLLGGA 231
modB PRK09421
molybdate ABC transporter permease subunit;
104-164 8.46e-03

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 36.44  E-value: 8.46e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 613387800 104 TGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGI 164
Cdd:PRK09421  93 RGAALAAAVMAFPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGT 153
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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