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Conserved domains on  [gi|613366473|gb|EZZ70754|]
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hypothetical protein V164_01138 [Staphylococcus aureus USA7]

Protein Classification

BCCT family transporter( domain architecture ID 10003438)

BCCT (betaine-carnitine-choline transporter) family transporter shares the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]; energized by pmf-driven proton symport; similar to Bacillus subtilis glycine betaine transporter OpuD

CATH:  1.20.5.430
Gene Ontology:  GO:0022857|GO:0071705|GO:0016020
PubMed:  20923416
TCDB:  2.A.15

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
9-498 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440903  Cd Length: 512  Bit Score: 610.61  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473   9 VFWVSLVICTIFVAFGAIFPKQLEKLTQNITSFIALHFSWYYLLLVLVILFVCVYILFSRYASITLGEEGEDPEFSLPSW 88
Cdd:COG1292   17 VFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRLGGDDAKPEFSTFSW 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  89 FAMLFSAGMGIGLVFWTTAEPISHAFKLTPIHKAGTQSAINDAMQFSFFHWGIHAWAVYGIVALVFAYFSFHKGYPGLVS 168
Cdd:COG1292   97 FAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGVEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLALAYFAYRRGLPLTIS 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 169 ATLTPLLGEKaMRGPLGGAIDVLAVIATVTGVAATLGFGALQINEGLHFLFNVPSNFTMQVILIVIATILFTWSAWSGID 248
Cdd:COG1292  177 SALYPLLGDR-IYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIAVITALFTISAVSGLD 255
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 249 KGIKTLSNINMLLAFVVLIGLFIVGPTLYILNTFTNGLGNYIANFFSMSLRIPSGGQKfQWLQNWTIFYWAWWISWAPFV 328
Cdd:COG1292  256 KGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGDT-GWLGGWTVFYWAWWIAWAPFV 334
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 329 GIFIARVSKGRTIKEFILGVLFVPAVVCFIFFAVFGASAIYLQDNHIADIAKAATE---TATFATLQHYPLGFVLSLITL 405
Cdd:COG1292  335 GLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGGDLAEAVAAgveAALFALLEQLPLGTILSVLAI 414
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 406 LVIMIFFVTSADSATYVLGMLSSSGDINPKSFVKVSWGIIMALFAIIMIYTGGTQAIQNLLIIAALPFSVVIIAMIWSLL 485
Cdd:COG1292  415 ILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIITALPFSFVLLLMCVSLV 494
                        490
                 ....*....|...
gi 613366473 486 KSLSEEKPRNSNK 498
Cdd:COG1292  495 KALREDPRRLRSA 507
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
9-498 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 610.61  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473   9 VFWVSLVICTIFVAFGAIFPKQLEKLTQNITSFIALHFSWYYLLLVLVILFVCVYILFSRYASITLGEEGEDPEFSLPSW 88
Cdd:COG1292   17 VFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRLGGDDAKPEFSTFSW 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  89 FAMLFSAGMGIGLVFWTTAEPISHAFKLTPIHKAGTQSAINDAMQFSFFHWGIHAWAVYGIVALVFAYFSFHKGYPGLVS 168
Cdd:COG1292   97 FAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGVEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLALAYFAYRRGLPLTIS 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 169 ATLTPLLGEKaMRGPLGGAIDVLAVIATVTGVAATLGFGALQINEGLHFLFNVPSNFTMQVILIVIATILFTWSAWSGID 248
Cdd:COG1292  177 SALYPLLGDR-IYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIAVITALFTISAVSGLD 255
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 249 KGIKTLSNINMLLAFVVLIGLFIVGPTLYILNTFTNGLGNYIANFFSMSLRIPSGGQKfQWLQNWTIFYWAWWISWAPFV 328
Cdd:COG1292  256 KGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGDT-GWLGGWTVFYWAWWIAWAPFV 334
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 329 GIFIARVSKGRTIKEFILGVLFVPAVVCFIFFAVFGASAIYLQDNHIADIAKAATE---TATFATLQHYPLGFVLSLITL 405
Cdd:COG1292  335 GLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGGDLAEAVAAgveAALFALLEQLPLGTILSVLAI 414
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 406 LVIMIFFVTSADSATYVLGMLSSSGDINPKSFVKVSWGIIMALFAIIMIYTGGTQAIQNLLIIAALPFSVVIIAMIWSLL 485
Cdd:COG1292  415 ILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIITALPFSFVLLLMCVSLV 494
                        490
                 ....*....|...
gi 613366473 486 KSLSEEKPRNSNK 498
Cdd:COG1292  495 KALREDPRRLRSA 507
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
9-491 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 594.90  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473    9 VFWVSLVICTIFVAFGAIFPKQLEKLTQNITSFIALHFSWYYLLLVLVILFVCVYILFSRYASITLGEEGEDPEFSLPSW 88
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473   89 FAMLFSAGMGIGLVFWTTAEPISHAFKLTPIHKAGTQSAINDAMQFSFFHWGIHAWAVYGIVALVFAYFSFHKGYPGLVS 168
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSPPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  169 ATLTPLLGEKaMRGPLGGAIDVLAVIATVTGVAATLGFGALQINEGLHFLFNVPSNFTMQVILIVIATILFTWSAWSGID 248
Cdd:pfam02028 161 SALYPLLGDR-IDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLD 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  249 KGIKTLSNINMLLAFVVLIGLFIVGPTLYILNTFTNGLGNYIANFFSMSLRIPSGGQKFQWLQNWTIFYWAWWISWAPFV 328
Cdd:pfam02028 240 KGIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGDTGGWLGGWTIFYWAWWIAWAPFV 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  329 GIFIARVSKGRTIKEFILGVLFVPAVVCFIFFAVFGASAIYLQDNH---IADIAKAATETATFATLQHYPLGFVLSLITL 405
Cdd:pfam02028 320 GMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGpgdLADAVEAGPPAALFALLEQLPLGTILSVLAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  406 LVIMIFFVTSADSATYVLGMLSSSGDINPKSFVKVSWGIIMALFAIIMIYTGGTQAIQNLLIIAALPFSVVIIAMIWSLL 485
Cdd:pfam02028 400 LLIIIFFVTSADSGTLVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLMCISLF 479

                  ....*.
gi 613366473  486 KSLSEE 491
Cdd:pfam02028 480 KALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
47-491 5.19e-154

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 447.18  E-value: 5.19e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473   47 SWYYLLLVLVILFVCVYILFSRYASITLGEEGEDPEFSLPSWFAMLFSAGMGIGLVFWTTAEPISHAFKLTPIHKAGTQS 126
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  127 AINDAMQFSFFHWGIHAWAVYGIVALVFAYFSFHKGYPGLVSATLTPLLGEKAmRGPLGGAIDVLAVIATVTGVAATLGF 206
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKV-NGPIGKAIDILALVATVFGVATSLGL 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  207 GALQINEGLHFLFNVPSNFTMQVILIVIATILFTWSAWSGIDKGIKTLSNINMLLAFVVLIGLFIVGPTLYILNTFTNGL 286
Cdd:TIGR00842 160 GAPQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSI 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  287 GNYIANFFSMSLRIPSGGQKFQWLQNWTIFYWAWWISWAPFVGIFIARVSKGRTIKEFILGVLFVPAVVCFIFFAVFGAS 366
Cdd:TIGR00842 240 GNYLQNFPQMSFRTDPDDGKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNS 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  367 AIYLQDNH----IADIAKAATETATFATLQHYPLGFVLSLITLLVIMIFFVTSADSATYVLGMLSSSG---DINPKSFVK 439
Cdd:TIGR00842 320 ALLLQQNGgfinGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGgqlGEEPPKWVR 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 613366473  440 VSWGIIMALFAIIMIYTGGT-QAIQNLLIIAALPFSVVIIAMIWSLLKSLSEE 491
Cdd:TIGR00842 400 VFWAVAIGLIALVLLFSGGSlAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK09928 PRK09928
choline transport protein BetT; Provisional
2-494 5.04e-124

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 378.27  E-value: 5.04e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473   2 KNKSVSLVFWVSLVICTIFVAFGAIFPKQLEKLTQNITSFIALHFSWYYLLLVLVILFVCVYILFSRYASITLGEEGEDP 81
Cdd:PRK09928  12 KDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSIKLGPEQSKP 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  82 EFSLPSWFAMLFSAGMGIGLVFWTTAEPISHaFKLTPIHKAGTQSAINDAMQFSFFHWGIHAWAVYGIVALVFAYFSFHK 161
Cdd:PRK09928  92 EFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQ-YMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYRY 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 162 GYPGLVSATLTPLLGEKaMRGPLGGAIDVLAVIATVTGVAATLGFGALQINEGLHFLFNVPSNFTMQVILIVIATILFTW 241
Cdd:PRK09928 171 NLPLTIRSALYPIFGKR-INGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIALSVIIATI 249
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 242 SAWSGIDKGIKTLSNINMLLAFVVLIGLFIVGPTLYILNTFTNGLGNYIANFFSMSLRIPSGGQKFQWLQNWTIFYWAWW 321
Cdd:PRK09928 250 SVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPTEWMNNWTLFFWAWW 329
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 322 ISWAPFVGIFIARVSKGRTIKEFILGVLFVPAVVCFIFFAVFGASAIYL---QDNHIADIAKAATETATFATLQHYPL-G 397
Cdd:PRK09928 330 VAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEiihGNAAFAEEAMAHPERGFYSLLAQYPAfT 409
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 398 FVLSLITLLVImIFFVTSADSATYVLGMLSSS-GDINPKS--FVKVSWGIIMALFAIIMIYTGGTQAIQNLLIIAALPFS 474
Cdd:PRK09928 410 FSASVATITGL-LFYVTSADSGALVLGNFTSKlKDINSDApnWLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFS 488
                        490       500
                 ....*....|....*....|
gi 613366473 475 VVIIAMIWSLLKSLSEEKPR 494
Cdd:PRK09928 489 FVIFFVMAGLYKSLKVEDYR 508
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
9-498 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 610.61  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473   9 VFWVSLVICTIFVAFGAIFPKQLEKLTQNITSFIALHFSWYYLLLVLVILFVCVYILFSRYASITLGEEGEDPEFSLPSW 88
Cdd:COG1292   17 VFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRLGGDDAKPEFSTFSW 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  89 FAMLFSAGMGIGLVFWTTAEPISHAFKLTPIHKAGTQSAINDAMQFSFFHWGIHAWAVYGIVALVFAYFSFHKGYPGLVS 168
Cdd:COG1292   97 FAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGVEPGSPEAARWAMAYTFFHWGLHAWAIYALVGLALAYFAYRRGLPLTIS 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 169 ATLTPLLGEKaMRGPLGGAIDVLAVIATVTGVAATLGFGALQINEGLHFLFNVPSNFTMQVILIVIATILFTWSAWSGID 248
Cdd:COG1292  177 SALYPLLGDR-IYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIAVITALFTISAVSGLD 255
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 249 KGIKTLSNINMLLAFVVLIGLFIVGPTLYILNTFTNGLGNYIANFFSMSLRIPSGGQKfQWLQNWTIFYWAWWISWAPFV 328
Cdd:COG1292  256 KGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGDT-GWLGGWTVFYWAWWIAWAPFV 334
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 329 GIFIARVSKGRTIKEFILGVLFVPAVVCFIFFAVFGASAIYLQDNHIADIAKAATE---TATFATLQHYPLGFVLSLITL 405
Cdd:COG1292  335 GLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGGDLAEAVAAgveAALFALLEQLPLGTILSVLAI 414
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 406 LVIMIFFVTSADSATYVLGMLSSSGDINPKSFVKVSWGIIMALFAIIMIYTGGTQAIQNLLIIAALPFSVVIIAMIWSLL 485
Cdd:COG1292  415 ILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASIITALPFSFVLLLMCVSLV 494
                        490
                 ....*....|...
gi 613366473 486 KSLSEEKPRNSNK 498
Cdd:COG1292  495 KALREDPRRLRSA 507
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
9-491 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 594.90  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473    9 VFWVSLVICTIFVAFGAIFPKQLEKLTQNITSFIALHFSWYYLLLVLVILFVCVYILFSRYASITLGEEGEDPEFSLPSW 88
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473   89 FAMLFSAGMGIGLVFWTTAEPISHAFKLTPIHKAGTQSAINDAMQFSFFHWGIHAWAVYGIVALVFAYFSFHKGYPGLVS 168
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSPPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  169 ATLTPLLGEKaMRGPLGGAIDVLAVIATVTGVAATLGFGALQINEGLHFLFNVPSNFTMQVILIVIATILFTWSAWSGID 248
Cdd:pfam02028 161 SALYPLLGDR-IDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLD 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  249 KGIKTLSNINMLLAFVVLIGLFIVGPTLYILNTFTNGLGNYIANFFSMSLRIPSGGQKFQWLQNWTIFYWAWWISWAPFV 328
Cdd:pfam02028 240 KGIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGDTGGWLGGWTIFYWAWWIAWAPFV 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  329 GIFIARVSKGRTIKEFILGVLFVPAVVCFIFFAVFGASAIYLQDNH---IADIAKAATETATFATLQHYPLGFVLSLITL 405
Cdd:pfam02028 320 GMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGpgdLADAVEAGPPAALFALLEQLPLGTILSVLAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  406 LVIMIFFVTSADSATYVLGMLSSSGDINPKSFVKVSWGIIMALFAIIMIYTGGTQAIQNLLIIAALPFSVVIIAMIWSLL 485
Cdd:pfam02028 400 LLIIIFFVTSADSGTLVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLMCISLF 479

                  ....*.
gi 613366473  486 KSLSEE 491
Cdd:pfam02028 480 KALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
47-491 5.19e-154

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 447.18  E-value: 5.19e-154
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473   47 SWYYLLLVLVILFVCVYILFSRYASITLGEEGEDPEFSLPSWFAMLFSAGMGIGLVFWTTAEPISHAFKLTPIHKAGTQS 126
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  127 AINDAMQFSFFHWGIHAWAVYGIVALVFAYFSFHKGYPGLVSATLTPLLGEKAmRGPLGGAIDVLAVIATVTGVAATLGF 206
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKV-NGPIGKAIDILALVATVFGVATSLGL 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  207 GALQINEGLHFLFNVPSNFTMQVILIVIATILFTWSAWSGIDKGIKTLSNINMLLAFVVLIGLFIVGPTLYILNTFTNGL 286
Cdd:TIGR00842 160 GAPQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSI 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  287 GNYIANFFSMSLRIPSGGQKFQWLQNWTIFYWAWWISWAPFVGIFIARVSKGRTIKEFILGVLFVPAVVCFIFFAVFGAS 366
Cdd:TIGR00842 240 GNYLQNFPQMSFRTDPDDGKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNS 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  367 AIYLQDNH----IADIAKAATETATFATLQHYPLGFVLSLITLLVIMIFFVTSADSATYVLGMLSSSG---DINPKSFVK 439
Cdd:TIGR00842 320 ALLLQQNGgfinGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGgqlGEEPPKWVR 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 613366473  440 VSWGIIMALFAIIMIYTGGT-QAIQNLLIIAALPFSVVIIAMIWSLLKSLSEE 491
Cdd:TIGR00842 400 VFWAVAIGLIALVLLFSGGSlAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK09928 PRK09928
choline transport protein BetT; Provisional
2-494 5.04e-124

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 378.27  E-value: 5.04e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473   2 KNKSVSLVFWVSLVICTIFVAFGAIFPKQLEKLTQNITSFIALHFSWYYLLLVLVILFVCVYILFSRYASITLGEEGEDP 81
Cdd:PRK09928  12 KDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSIKLGPEQSKP 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  82 EFSLPSWFAMLFSAGMGIGLVFWTTAEPISHaFKLTPIHKAGTQSAINDAMQFSFFHWGIHAWAVYGIVALVFAYFSFHK 161
Cdd:PRK09928  92 EFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQ-YMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYRY 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 162 GYPGLVSATLTPLLGEKaMRGPLGGAIDVLAVIATVTGVAATLGFGALQINEGLHFLFNVPSNFTMQVILIVIATILFTW 241
Cdd:PRK09928 171 NLPLTIRSALYPIFGKR-INGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIALSVIIATI 249
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 242 SAWSGIDKGIKTLSNINMLLAFVVLIGLFIVGPTLYILNTFTNGLGNYIANFFSMSLRIPSGGQKFQWLQNWTIFYWAWW 321
Cdd:PRK09928 250 SVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPTEWMNNWTLFFWAWW 329
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 322 ISWAPFVGIFIARVSKGRTIKEFILGVLFVPAVVCFIFFAVFGASAIYL---QDNHIADIAKAATETATFATLQHYPL-G 397
Cdd:PRK09928 330 VAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEiihGNAAFAEEAMAHPERGFYSLLAQYPAfT 409
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 398 FVLSLITLLVImIFFVTSADSATYVLGMLSSS-GDINPKS--FVKVSWGIIMALFAIIMIYTGGTQAIQNLLIIAALPFS 474
Cdd:PRK09928 410 FSASVATITGL-LFYVTSADSGALVLGNFTSKlKDINSDApnWLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFS 488
                        490       500
                 ....*....|....*....|
gi 613366473 475 VVIIAMIWSLLKSLSEEKPR 494
Cdd:PRK09928 489 FVIFFVMAGLYKSLKVEDYR 508
PRK03356 PRK03356
L-carnitine/gamma-butyrobetaine antiport BCCT transporter;
9-486 1.66e-72

L-carnitine/gamma-butyrobetaine antiport BCCT transporter;


Pssm-ID: 179568  Cd Length: 504  Bit Score: 238.87  E-value: 1.66e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473   9 VFWVSLVICTIFVAFGAIFPKQLEKLTQNITSFIALHFSWYYLLLVLVILFVCVYILFSRYASITLGEEgeDPEFSLPSW 88
Cdd:PRK03356  14 VFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGDE--KPEFSTASW 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  89 FAMLFSAGMGIGLVFWTTAE----PISHAFKLTPIhkagTQSAINDAMQFSFFHWGIHAWAVYGIVALVFAYFSFHKGYP 164
Cdd:PRK03356  92 IFMMFASCTSAAVLFWGSIEiyyyISTPPFGLEPN----STGAKELGLAYSLFHWGPLPWATYSFLSVAFGYFFFVRKMD 167
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 165 GL-VSATLTPLLGEKAMRGPLGGAIDVLAVIATVTGVAATLGFGALQINEGLHFLFNVPSNFTMQVILIVIATILFTWSA 243
Cdd:PRK03356 168 VIrPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICV 247
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 244 WSGIDKGIKTLSNINMLLAFVVLIGLFIVGPTLYILNTFTNGLGNYIANFFSMSLRIPSGGqKFQWLQNWTIFYWAWWIS 323
Cdd:PRK03356 248 ACGLQKGVRIASDVRSYLSFLMLGWVFIVGGTSFIMNYFTDSVGMLLMYLPRMLFYTDPIG-KGGFPQGWTVFYWAWWVI 326
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 324 WAPFVGIFIARVSKGRTIKEFILGVLFVPAVVCFIFFAVFGASAIYLQDNHIADIAKAATETATFATLQHYPLGFVLSLI 403
Cdd:PRK03356 327 YAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLMDKNIINIPNLIEQYGVARAIIETWAALPLSTA 406
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 404 TLLVIMIFF----VTSADSATYVLGMLSSSG---DINPKSFVKVSWGIIMALFAIIMIYTGGTQAIQNLLIIAALPFSVV 476
Cdd:PRK03356 407 TMWGFFILCfiatVTLINACSYTLAMSTCREvrdGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFV 486
                        490
                 ....*....|
gi 613366473 477 IIAMIWSLLK 486
Cdd:PRK03356 487 NIMVTLSFIK 496
PRK09950 PRK09950
putative transporter; Provisional
12-491 4.58e-71

putative transporter; Provisional


Pssm-ID: 236636  Cd Length: 506  Bit Score: 235.45  E-value: 4.58e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  12 VSLVICTIFVAFGAIFPKQLEKLTQNITSFIALHFSWYYLLLVLVILFVCVYILFSRYASITLGEEgeDPEFSLPSWFAM 91
Cdd:PRK09950  15 TSLLAVFFIVAALSLFPQQSAAAANTIFQWVTRTFGSPVQLFVLLAMILVLYLATSKYGNIRLGEG--KPEYSTLSWLFM 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473  92 LFSAGMGIGLVFWTTAEpISHAFKLTPIHKAG-TQSAINDAMQFSFFHWGIHAWAVYGIVALVFAYfSFH-KGYPGL-VS 168
Cdd:PRK09950  93 FICAGLGSSTLYWGVME-WAYYYQTPGLNIAPrSPKALEYSVSYSFFHWGISAWATYALASLIMAY-HFHvRKNKGLsLS 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 169 ATLTPLLGEKAmRGPLGGAIDVLAVIATVTGVAATLGFGALQINEGLHFLFNVPSNFTMQVILIVIATILFTWSAWSGID 248
Cdd:PRK09950 171 GIIAAITGVKP-QGPWGRLVDLMFLIATVGALTISLVVTAATFTRGLSALTGLPNNFTVQAFVILLSGVIFCLSSYIGID 249
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 249 KGIKTLSNINMLLAFVVLIGLFIVGPTLYILNTFTNGLGNYIANFFSMSLRI-PSGGQKFQwlQNWTIFYWAWWISWAPF 327
Cdd:PRK09950 250 NGLQRLSKMVGWGAFLFALLVLIVGPTEFITNNIINSIGLTTQNFLQMSLFTdPMGDGSFT--RNWTVFYWLWWISYTPG 327
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 328 VGIFIARVSKGRTIKEFILGVLFVPAVVCFIFFAVFGASAIYLQDNHIADIAKAATETATFATLQH----YPLGFVLSLI 403
Cdd:PRK09950 328 VAMFVTRVSRGRKIKEVIWGLILGSSVGCWFFFGVLESYAIHQFINGVINVPQILNTLGGETAVQQllssLPAGKLFLAA 407
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613366473 404 TLLVIMIFFVTSADSATYVLGMLS----SSGDiNPKSFVKVSWGIIMALFAIIMIYTGGT-QAIQNLLIIAALPFSVVII 478
Cdd:PRK09950 408 YLGIMIIFLASHMDAVAYTMAATStrnlREGD-DPDRGLRLFWCVVITLIPLSILFTGASlDTMKTTVVLTALPFLVILL 486
                        490
                 ....*....|...
gi 613366473 479 AMIWSLLKSLSEE 491
Cdd:PRK09950 487 IKVYGFIRWLKQD 499
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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