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Conserved domains on  [gi|613307156|gb|EZZ12251|]
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preprotein translocase, YajC subunit [Staphylococcus aureus Sau 46]

Protein Classification

preprotein translocase subunit YajC( domain architecture ID 10004811)

preprotein translocase subunit YajC forms a complex with SecD and SecF and plays a role in stabilizing and regulating secretion through the SecYEG transmembrane complex via SecA

Gene Ontology:  GO:0015031|GO:0005886
PubMed:  20801097|10066476|12068816|9305629|23337498

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YajC COG1862
Protein translocase subunit YajC [Intracellular trafficking, secretion, and vesicular ...
 3-83 1.29e-32

Protein translocase subunit YajC [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 441467  Cd Length: 102  Bit Score: 108.73  E-value: 1.29e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613307156   3 FSLLIYIVVIFAVMYFLMIRPQQKRAKQHRELINNIQSGQRITTIGGIKGTVKAVDETTVVITVnGHGTELTFEKPAIKQ 82
Cdd:COG1862   14 LMSLLPLVLIFVIFYFLMIRPQQKRQKEHKEMLSSLKKGDEVVTIGGIHGTVVKVDDDTVTLEI-ADGVKVKVERSAIAR 92


                 .
gi 613307156  83 V 83
Cdd:COG1862   93 V 93
 
Name Accession Description Interval E-value
YajC COG1862
Protein translocase subunit YajC [Intracellular trafficking, secretion, and vesicular ...
 3-83 1.29e-32

Protein translocase subunit YajC [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441467  Cd Length: 102  Bit Score: 108.73  E-value: 1.29e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613307156   3 FSLLIYIVVIFAVMYFLMIRPQQKRAKQHRELINNIQSGQRITTIGGIKGTVKAVDETTVVITVnGHGTELTFEKPAIKQ 82
Cdd:COG1862   14 LMSLLPLVLIFVIFYFLMIRPQQKRQKEHKEMLSSLKKGDEVVTIGGIHGTVVKVDDDTVTLEI-ADGVKVKVERSAIAR 92


                 .
gi 613307156  83 V 83
Cdd:COG1862   93 V 93
YajC pfam02699
Preprotein translocase subunit; See.
 4-80 6.48e-29

Preprotein translocase subunit; See.


Pssm-ID: 460655  Cd Length: 78  Bit Score: 98.24  E-value: 6.48e-29
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 613307156   4 SLLIYIVVIFAVMYFLMIRPQQKRAKQHRELINNIQSGQRITTIGGIKGTVKAVDETTVVITVNGhGTELTFEKPAI 80
Cdd:pfam02699  1 SSLLPLVLIFVIFYFLMIRPQQKRQKEHQEMLDSLKKGDEVVTIGGIHGKVVKVDDDEVTLEIAA-GVKIKVERSAI 76
yajC PRK05585
preprotein translocase subunit YajC; Validated
 3-85 7.03e-24

preprotein translocase subunit YajC; Validated


Pssm-ID: 235518  Cd Length: 106  Bit Score: 86.49  E-value: 7.03e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613307156   3 FSLLIYIVVIFAVMYFLMIRPQQKRAKQHRELINNIQSGQRITTIGGIKGTVKAVDETTVVITVNgHGTELTFEKPAIKQ 82
Cdd:PRK05585  18 LSSLLPLVVFFAIFYFLIIRPQQKRQKEHKKMLSSLAKGDEVVTNGGIIGKVTKVSEDFVIIELN-DDTEIKIQKSAIAA 96


                 ...
gi 613307156  83 VDP 85
Cdd:PRK05585  97 VLP 99
yajC TIGR00739
preprotein translocase, YajC subunit; While this protein is part of the preprotein translocase ...
 3-85 1.07e-21

preprotein translocase, YajC subunit; While this protein is part of the preprotein translocase in Escherichia coli, it is not essential for viability or protein secretion. The N-terminus region contains a predicted membrane-spanning region followed by a region consisting almost entirely of residues with charged (acidic, basic, or zwitterionic) side chains. This small protein is about 100 residues in length, and is restricted to bacteria; however, this protein is absent from some lineages, including spirochetes and Mycoplasmas. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273243  Cd Length: 84  Bit Score: 80.42  E-value: 1.07e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613307156   3 FSLLIYIVVIFAVMYFLMIRPQQKRAKQHRELINNIQSGQRITTIGGIKGTVKAVDETTVVITVNGhGTELTFEKPAIKQ 82
Cdd:TIGR00739  3 LTTLLPLVLIFLIFYFLIIRPQRKRRKAHKKLIESLKKGDKVLTIGGIIGTVTKIAENTIVIELND-NTEITFSKNAIVE 81


                 ...
gi 613307156  83 VDP 85
Cdd:TIGR00739 82 VLP 84
 
Name Accession Description Interval E-value
YajC COG1862
Protein translocase subunit YajC [Intracellular trafficking, secretion, and vesicular ...
 3-83 1.29e-32

Protein translocase subunit YajC [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441467  Cd Length: 102  Bit Score: 108.73  E-value: 1.29e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613307156   3 FSLLIYIVVIFAVMYFLMIRPQQKRAKQHRELINNIQSGQRITTIGGIKGTVKAVDETTVVITVnGHGTELTFEKPAIKQ 82
Cdd:COG1862   14 LMSLLPLVLIFVIFYFLMIRPQQKRQKEHKEMLSSLKKGDEVVTIGGIHGTVVKVDDDTVTLEI-ADGVKVKVERSAIAR 92


                 .
gi 613307156  83 V 83
Cdd:COG1862   93 V 93
YajC pfam02699
Preprotein translocase subunit; See.
 4-80 6.48e-29

Preprotein translocase subunit; See.


Pssm-ID: 460655  Cd Length: 78  Bit Score: 98.24  E-value: 6.48e-29
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 613307156   4 SLLIYIVVIFAVMYFLMIRPQQKRAKQHRELINNIQSGQRITTIGGIKGTVKAVDETTVVITVNGhGTELTFEKPAI 80
Cdd:pfam02699  1 SSLLPLVLIFVIFYFLMIRPQQKRQKEHQEMLDSLKKGDEVVTIGGIHGKVVKVDDDEVTLEIAA-GVKIKVERSAI 76
yajC PRK05585
preprotein translocase subunit YajC; Validated
 3-85 7.03e-24

preprotein translocase subunit YajC; Validated


Pssm-ID: 235518  Cd Length: 106  Bit Score: 86.49  E-value: 7.03e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613307156   3 FSLLIYIVVIFAVMYFLMIRPQQKRAKQHRELINNIQSGQRITTIGGIKGTVKAVDETTVVITVNgHGTELTFEKPAIKQ 82
Cdd:PRK05585  18 LSSLLPLVVFFAIFYFLIIRPQQKRQKEHKKMLSSLAKGDEVVTNGGIIGKVTKVSEDFVIIELN-DDTEIKIQKSAIAA 96


                 ...
gi 613307156  83 VDP 85
Cdd:PRK05585  97 VLP 99
yajC TIGR00739
preprotein translocase, YajC subunit; While this protein is part of the preprotein translocase ...
 3-85 1.07e-21

preprotein translocase, YajC subunit; While this protein is part of the preprotein translocase in Escherichia coli, it is not essential for viability or protein secretion. The N-terminus region contains a predicted membrane-spanning region followed by a region consisting almost entirely of residues with charged (acidic, basic, or zwitterionic) side chains. This small protein is about 100 residues in length, and is restricted to bacteria; however, this protein is absent from some lineages, including spirochetes and Mycoplasmas. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273243  Cd Length: 84  Bit Score: 80.42  E-value: 1.07e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613307156   3 FSLLIYIVVIFAVMYFLMIRPQQKRAKQHRELINNIQSGQRITTIGGIKGTVKAVDETTVVITVNGhGTELTFEKPAIKQ 82
Cdd:TIGR00739  3 LTTLLPLVLIFLIFYFLIIRPQRKRRKAHKKLIESLKKGDKVLTIGGIIGTVTKIAENTIVIELND-NTEITFSKNAIVE 81


                 ...
gi 613307156  83 VDP 85
Cdd:TIGR00739 82 VLP 84
yajC PRK06531
preprotein translocase subunit YajC; Validated
 1-85 5.92e-15

preprotein translocase subunit YajC; Validated


Pssm-ID: 235822  Cd Length: 113  Bit Score: 64.05  E-value: 5.92e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 613307156   1 MQFSLLIYIVVIFAVMYFlMIRPQQKRAKQHRELINNIQSGQRITTIGGIKGTVKAVDETTVVITVNGHGTELTFEKPAI 80
Cdd:PRK06531   1 MGIPTIIMFVVMLGLIFF-MQRQQKKQAQERQNQLNAIQKGDEVVTIGGLYGTVDEVDTEAKTIVLDVDGVYLTFELAAI 79


                 ....*
gi 613307156  81 KQVDP 85
Cdd:PRK06531  80 KRVVP 84
yajC PRK05886
preprotein translocase subunit YajC; Validated
 5-62 2.91e-05

preprotein translocase subunit YajC; Validated


Pssm-ID: 235636  Cd Length: 109  Bit Score: 39.04  E-value: 2.91e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 613307156   5 LLIYIVVIFAVMYFLMIRpqQKRAKQHR-ELINNIQSGQRITTIGGIKGTVKAVDETTV 62
Cdd:PRK05886   7 FLPFLLIMGGFMYFASRR--QRKAMQATiDLHESLQPGDRVHTTSGLQATIVGITDDTV 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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