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Conserved domains on  [gi|612905144|gb|EZV16825|]
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hypothetical protein U926_02341 [Staphylococcus aureus 12S00881]

Protein Classification

TrkH family potassium uptake protein( domain architecture ID 11415019)

TrkH family potassium uptake protein is the membrane component of a potassium transport system and may bind other membrane components as well as periplasmic proteins; similar to Bacillus subtilis Ktr system potassium uptake protein D

Gene Ontology:  GO:0015079|GO:0030001|GO:0008324
PubMed:  20333436|10423425

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TrkG COG0168
Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];
12-419 1.31e-88

Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];


:

Pssm-ID: 439938 [Multi-domain]  Cd Length: 414  Bit Score: 275.42  E-value: 1.31e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  12 LMLFFSTTIIGALLLYLPF-TGKKPISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTL 90
Cdd:COG0168    6 FLIVALVWLVGALLLALPFaLSGGGLSFLDALFEAVSGVTTTGLTVVDTLDTLPKFGLLWRSLLQWLGGLGIIVLAVAIL 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  91 VFLNrkisMKNRFLIMV-TWNIDEPGGVIKLIKHLAIYSLVTELIGMICLCLSfipkfgiGKGLFLSLFTSVSAFNNAGF 169
Cdd:COG0168   86 PLLG----IGGRQLFQAeLPNEKLLPRIVRTAKALWLIYLGLTLIGALLLWLA-------GMALFDAIFHAFSAFSTGGF 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144 170 ALFKNNLIDYsNDPIVIITISILIIFGGIGHFVVIDFINCKKLSKLSLHSKLVLTTTSILIIIGAITFFLleqFNTMQNM 249
Cdd:COG0168  155 STHDDSLGAF-NSPAIELVIIVFMILGGLGFPVHYDLLRYRRFRRLFSDTELRLYLTLILLVVGLLALFL---WNNGTLG 230
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144 250 GLVEKIGNSFFQSVTT-RTAGFNSIDIASINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIRKE------ 322
Cdd:COG0168  231 SLGEALRAALFQVVSIlTTTGFATVDYGQWPPFSLLLLILLMFIGGSAGSTAGGIKVTRFAVLLKAIRRELRRLihpnav 310
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144 323 NNVFVFNKEISNKHIKLSIVTINISFLFISIITFILSIINpNISLIKLLFEVVSAFGTVGLSMNLTT-EYHGITKIIIIF 401
Cdd:COG0168  311 RPVRIGGRRIPEEVIRKALAFFFLYLLLVVVGTLLLSLTE-GLDFLTALFEVASAFGNVGLSLGITGaSLSDAGKLVLIF 389
                        410
                 ....*....|....*...
gi 612905144 402 VMLCGKVGLLTLLRTFIP 419
Cdd:COG0168  390 LMLLGRLEILTVLVLLTP 407
 
Name Accession Description Interval E-value
TrkG COG0168
Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];
12-419 1.31e-88

Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];


Pssm-ID: 439938 [Multi-domain]  Cd Length: 414  Bit Score: 275.42  E-value: 1.31e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  12 LMLFFSTTIIGALLLYLPF-TGKKPISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTL 90
Cdd:COG0168    6 FLIVALVWLVGALLLALPFaLSGGGLSFLDALFEAVSGVTTTGLTVVDTLDTLPKFGLLWRSLLQWLGGLGIIVLAVAIL 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  91 VFLNrkisMKNRFLIMV-TWNIDEPGGVIKLIKHLAIYSLVTELIGMICLCLSfipkfgiGKGLFLSLFTSVSAFNNAGF 169
Cdd:COG0168   86 PLLG----IGGRQLFQAeLPNEKLLPRIVRTAKALWLIYLGLTLIGALLLWLA-------GMALFDAIFHAFSAFSTGGF 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144 170 ALFKNNLIDYsNDPIVIITISILIIFGGIGHFVVIDFINCKKLSKLSLHSKLVLTTTSILIIIGAITFFLleqFNTMQNM 249
Cdd:COG0168  155 STHDDSLGAF-NSPAIELVIIVFMILGGLGFPVHYDLLRYRRFRRLFSDTELRLYLTLILLVVGLLALFL---WNNGTLG 230
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144 250 GLVEKIGNSFFQSVTT-RTAGFNSIDIASINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIRKE------ 322
Cdd:COG0168  231 SLGEALRAALFQVVSIlTTTGFATVDYGQWPPFSLLLLILLMFIGGSAGSTAGGIKVTRFAVLLKAIRRELRRLihpnav 310
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144 323 NNVFVFNKEISNKHIKLSIVTINISFLFISIITFILSIINpNISLIKLLFEVVSAFGTVGLSMNLTT-EYHGITKIIIIF 401
Cdd:COG0168  311 RPVRIGGRRIPEEVIRKALAFFFLYLLLVVVGTLLLSLTE-GLDFLTALFEVASAFGNVGLSLGITGaSLSDAGKLVLIF 389
                        410
                 ....*....|....*...
gi 612905144 402 VMLCGKVGLLTLLRTFIP 419
Cdd:COG0168  390 LMLLGRLEILTVLVLLTP 407
2a38 TIGR00933
potassium uptake protein, TrkH family; The proteins of the Trk family are derived from ...
25-407 3.98e-77

potassium uptake protein, TrkH family; The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273349  Cd Length: 391  Bit Score: 244.87  E-value: 3.98e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144   25 LLYLPF--TGKKPISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTLVFLNRKISMKNR 102
Cdd:TIGR00933   1 LLALPFviSSGLPLSFIDALFTATSAVTTTGLTVLDTLESLPKAGLFLRSLLQQIGGLGFMVLAVAILILLGKKISLGAR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  103 FLIMVTWNIDEPGGVIKLIKHLAIYSLVTELIGMICLCLSFIPKFGigKGLFLSLFTSVSAFNNAGFALFKNNLIDYSND 182
Cdd:TIGR00933  81 LYLAEALGPLSDDKLLPLIKNTAKFIFVIYLLGTILLAVRFVLTGW--MPLFDAIFHSISAFNNGGFSTHSDSSIGYFHD 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  183 PIVIITISILIIFGGIGHFVVIDFINC---KKLSKLSLHSKLVLTTTSILIIIGAITFFLLEQFNTMQNMGLVEKIGNSF 259
Cdd:TIGR00933 159 PSVNLVIAFLIILGGLGFTVHYDVYLHlrkRVFKSLSLDTKVRLFVTFLLLAIGFILFLLLERGNTLYSYSFGALLLSAF 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  260 FQSVTTRTAGFNSIDIASINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIRK-ENNVFVFNKEISNKHIK 338
Cdd:TIGR00933 239 FQSSTLRTAGFSTIDFAALPTATLVLLLLLMFIGGCSGSTAGGIKTTTFAILLKQVYREIRRgIHPRIIFSRRIGGKTID 318
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 612905144  339 LSIVTINISFLFISIITFILSI---INPNISLIKLLFEVVSAFGTVGLSMNLTT-EYHGITKIIIIFVMLCGK 407
Cdd:TIGR00933 319 KAILISVWSFFLVFALIFLLSIlelISSGYDFLTSLFEVVSAFGTVGLSVGLTTaNLPDAGKLILIVLMFIGR 391
TrkH pfam02386
Cation transport protein; This family consists of various cation transport proteins (Trk) and ...
34-428 1.84e-40

Cation transport protein; This family consists of various cation transport proteins (Trk) and V-type sodium ATP synthase subunit J or translocating ATPase J EC:3.6.1.34. These proteins are involved in active sodium up-take utilizing ATP in the process. TrkH a member of the family from E. coli is a hydrophobic membrane protein and determines the specificity and kinetics of cation transport by the TrK system in E. coli.


Pssm-ID: 280534  Cd Length: 491  Bit Score: 150.65  E-value: 1.84e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144   34 KPISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTLVFLNRKismkNRFLIMVTWNIDE 113
Cdd:pfam02386  59 PSLTFLDALFEAVSGLTTTGLTVIDVETSLPRSGLFYRAQLQWIGGLGTMVLAVLSWPTLGRG----SAFLYLSEMQGPE 134
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  114 PGGVI-----KLIKHLAIYSLVTELIGMICLC--LSFIPKFGIGKGLFLSLFTSVSAFNNAGFALFKNNLIDYSNDPIVI 186
Cdd:pfam02386 135 LGGKEypslsELCKILWVYYFGLTILAFVAYFvfIYTAKGYLEVVPLWWAFFHSMSAFSNGGFSLTPNSIASFNTNPVIL 214
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  187 ITISILIIFGGIGHFVVIDFI---------NCKKLSKLSLHSKLVLTTTSILIIIGAI---------------TFFLLEQ 242
Cdd:pfam02386 215 WVATSFIILGGIGFPIHLRVIiwimkkilrFKNFKESLSLLLDHPRRCFTLLFASGFTwvlflelavlnvtdwILFMVLD 294
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  243 FNT--MQNMGLVEKIGNSFFQSVTTRTAGFNSIDIASINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIR 320
Cdd:pfam02386 295 FGShvVGSIPKGYRVLNAFFQSVSTRTAGFSVVDISNLHPAIKVSYVLMMFIGGAPGSTAGGIKRTRVYEEFSLGKYEIH 374
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  321 KENNV-FVFNKEISNKHIKLSIVTINISF---LFISIITFILSIINPN-ISLIKLLFEVVSAFGTVGLS----MNLTTEY 391
Cdd:pfam02386 375 GDPEPrAVSTKSIDGKHLTRQLSEDLWYLflgLFIICICEGLKLSDVGpFSFFDILFEVVSAYGTVGLSlgtnHSLSAQF 454
                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 612905144  392 HGITKIIIIFVMLCGKVGLLTLLRTFIPPKSPKNYRY 428
Cdd:pfam02386 455 TTIAKLVIIALMIRGRLEGLPVLLDFAILPSDKSWEY 491
 
Name Accession Description Interval E-value
TrkG COG0168
Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];
12-419 1.31e-88

Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];


Pssm-ID: 439938 [Multi-domain]  Cd Length: 414  Bit Score: 275.42  E-value: 1.31e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  12 LMLFFSTTIIGALLLYLPF-TGKKPISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTL 90
Cdd:COG0168    6 FLIVALVWLVGALLLALPFaLSGGGLSFLDALFEAVSGVTTTGLTVVDTLDTLPKFGLLWRSLLQWLGGLGIIVLAVAIL 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  91 VFLNrkisMKNRFLIMV-TWNIDEPGGVIKLIKHLAIYSLVTELIGMICLCLSfipkfgiGKGLFLSLFTSVSAFNNAGF 169
Cdd:COG0168   86 PLLG----IGGRQLFQAeLPNEKLLPRIVRTAKALWLIYLGLTLIGALLLWLA-------GMALFDAIFHAFSAFSTGGF 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144 170 ALFKNNLIDYsNDPIVIITISILIIFGGIGHFVVIDFINCKKLSKLSLHSKLVLTTTSILIIIGAITFFLleqFNTMQNM 249
Cdd:COG0168  155 STHDDSLGAF-NSPAIELVIIVFMILGGLGFPVHYDLLRYRRFRRLFSDTELRLYLTLILLVVGLLALFL---WNNGTLG 230
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144 250 GLVEKIGNSFFQSVTT-RTAGFNSIDIASINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIRKE------ 322
Cdd:COG0168  231 SLGEALRAALFQVVSIlTTTGFATVDYGQWPPFSLLLLILLMFIGGSAGSTAGGIKVTRFAVLLKAIRRELRRLihpnav 310
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144 323 NNVFVFNKEISNKHIKLSIVTINISFLFISIITFILSIINpNISLIKLLFEVVSAFGTVGLSMNLTT-EYHGITKIIIIF 401
Cdd:COG0168  311 RPVRIGGRRIPEEVIRKALAFFFLYLLLVVVGTLLLSLTE-GLDFLTALFEVASAFGNVGLSLGITGaSLSDAGKLVLIF 389
                        410
                 ....*....|....*...
gi 612905144 402 VMLCGKVGLLTLLRTFIP 419
Cdd:COG0168  390 LMLLGRLEILTVLVLLTP 407
2a38 TIGR00933
potassium uptake protein, TrkH family; The proteins of the Trk family are derived from ...
25-407 3.98e-77

potassium uptake protein, TrkH family; The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273349  Cd Length: 391  Bit Score: 244.87  E-value: 3.98e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144   25 LLYLPF--TGKKPISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTLVFLNRKISMKNR 102
Cdd:TIGR00933   1 LLALPFviSSGLPLSFIDALFTATSAVTTTGLTVLDTLESLPKAGLFLRSLLQQIGGLGFMVLAVAILILLGKKISLGAR 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  103 FLIMVTWNIDEPGGVIKLIKHLAIYSLVTELIGMICLCLSFIPKFGigKGLFLSLFTSVSAFNNAGFALFKNNLIDYSND 182
Cdd:TIGR00933  81 LYLAEALGPLSDDKLLPLIKNTAKFIFVIYLLGTILLAVRFVLTGW--MPLFDAIFHSISAFNNGGFSTHSDSSIGYFHD 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  183 PIVIITISILIIFGGIGHFVVIDFINC---KKLSKLSLHSKLVLTTTSILIIIGAITFFLLEQFNTMQNMGLVEKIGNSF 259
Cdd:TIGR00933 159 PSVNLVIAFLIILGGLGFTVHYDVYLHlrkRVFKSLSLDTKVRLFVTFLLLAIGFILFLLLERGNTLYSYSFGALLLSAF 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  260 FQSVTTRTAGFNSIDIASINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIRK-ENNVFVFNKEISNKHIK 338
Cdd:TIGR00933 239 FQSSTLRTAGFSTIDFAALPTATLVLLLLLMFIGGCSGSTAGGIKTTTFAILLKQVYREIRRgIHPRIIFSRRIGGKTID 318
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 612905144  339 LSIVTINISFLFISIITFILSI---INPNISLIKLLFEVVSAFGTVGLSMNLTT-EYHGITKIIIIFVMLCGK 407
Cdd:TIGR00933 319 KAILISVWSFFLVFALIFLLSIlelISSGYDFLTSLFEVVSAFGTVGLSVGLTTaNLPDAGKLILIVLMFIGR 391
TrkH pfam02386
Cation transport protein; This family consists of various cation transport proteins (Trk) and ...
34-428 1.84e-40

Cation transport protein; This family consists of various cation transport proteins (Trk) and V-type sodium ATP synthase subunit J or translocating ATPase J EC:3.6.1.34. These proteins are involved in active sodium up-take utilizing ATP in the process. TrkH a member of the family from E. coli is a hydrophobic membrane protein and determines the specificity and kinetics of cation transport by the TrK system in E. coli.


Pssm-ID: 280534  Cd Length: 491  Bit Score: 150.65  E-value: 1.84e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144   34 KPISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTLVFLNRKismkNRFLIMVTWNIDE 113
Cdd:pfam02386  59 PSLTFLDALFEAVSGLTTTGLTVIDVETSLPRSGLFYRAQLQWIGGLGTMVLAVLSWPTLGRG----SAFLYLSEMQGPE 134
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  114 PGGVI-----KLIKHLAIYSLVTELIGMICLC--LSFIPKFGIGKGLFLSLFTSVSAFNNAGFALFKNNLIDYSNDPIVI 186
Cdd:pfam02386 135 LGGKEypslsELCKILWVYYFGLTILAFVAYFvfIYTAKGYLEVVPLWWAFFHSMSAFSNGGFSLTPNSIASFNTNPVIL 214
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  187 ITISILIIFGGIGHFVVIDFI---------NCKKLSKLSLHSKLVLTTTSILIIIGAI---------------TFFLLEQ 242
Cdd:pfam02386 215 WVATSFIILGGIGFPIHLRVIiwimkkilrFKNFKESLSLLLDHPRRCFTLLFASGFTwvlflelavlnvtdwILFMVLD 294
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  243 FNT--MQNMGLVEKIGNSFFQSVTTRTAGFNSIDIASINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIR 320
Cdd:pfam02386 295 FGShvVGSIPKGYRVLNAFFQSVSTRTAGFSVVDISNLHPAIKVSYVLMMFIGGAPGSTAGGIKRTRVYEEFSLGKYEIH 374
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  321 KENNV-FVFNKEISNKHIKLSIVTINISF---LFISIITFILSIINPN-ISLIKLLFEVVSAFGTVGLS----MNLTTEY 391
Cdd:pfam02386 375 GDPEPrAVSTKSIDGKHLTRQLSEDLWYLflgLFIICICEGLKLSDVGpFSFFDILFEVVSAYGTVGLSlgtnHSLSAQF 454
                         410       420       430
                  ....*....|....*....|....*....|....*..
gi 612905144  392 HGITKIIIIFVMLCGKVGLLTLLRTFIPPKSPKNYRY 428
Cdd:pfam02386 455 TTIAKLVIIALMIRGRLEGLPVLLDFAILPSDKSWEY 491
2a38euk TIGR00934
potassium uptake protein, Trk family; The proteins of the Trk family are derived from ...
112-407 2.31e-21

potassium uptake protein, Trk family; The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. This family is specific for the eukaryotic Trk system. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130009 [Multi-domain]  Cd Length: 800  Bit Score: 96.98  E-value: 2.31e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  112 DEPGGV----IKLI-KHLAIYSLVTELIGMICLCL---------SFIPKFGIGKGLFlSLFTSVSAFNNAGFALFKNNLI 177
Cdd:TIGR00934 438 DELGGIeyraLKCLcSIVLVYFLGFNILGFVLLLPwinhvktysEVVRSKGVSPTWW-GFFTAMSAFANLGLTLTPESMV 516
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  178 DYSNDPIVIITISILIIFGGIGH------FVVIDFINCKKLSKLS----------------LHSKL---VLTTTSILIII 232
Cdd:TIGR00934 517 SFNKNSYLLLLMIWFIIIGNTGFpiflrlIIWILFKISPDLSKRKeslgflldhprrcftlLFPSGatwWLFFTLVGLNA 596
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  233 GAITFFLLEQFNT--MQNMGLVEKIGNSFFQSVTTRTAGFNSIDIASINKSTALMLMLLMFIGGAPLsaAGGIKITTFAV 310
Cdd:TIGR00934 597 IDLILFIILDWGSsvVDGLSKGIKVLNGLFQSVSTRTAGFTVVDLSQLHPAIQVSYMLMMYVSVLPL--AISIRRTNVYE 674
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  311 AFIFVLNYIRKENNvfvfNKEISNKHIKLSIVTINISFL--FISIITFILSI---------INPNISLIKLLFEVVSAFG 379
Cdd:TIGR00934 675 EQSLGLYNEENEEH----EGESSTKSFIGAHLRRQLSFDlwYIFLGLFIICIcegrkiqdpDPPNFNVFNILFEVVSAYG 750
                         330       340       350
                  ....*....|....*....|....*....|....*
gi 612905144  380 TVGLSMNLTTEYHG-------ITKIIIIFVMLCGK 407
Cdd:TIGR00934 751 TVGLSLGYSCSNYSfsgqfttLSKLVIIAMLIRGR 785
2a38euk TIGR00934
potassium uptake protein, Trk family; The proteins of the Trk family are derived from ...
8-79 2.23e-07

potassium uptake protein, Trk family; The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. This family is specific for the eukaryotic Trk system. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130009 [Multi-domain]  Cd Length: 800  Bit Score: 53.06  E-value: 2.23e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 612905144    8 LYFYLMLFFSTTIIGALLLYlPFTGKKPiSFLDALFIASSAFTVTGLSPVDIGSqFNILGEIVILLLIQIGG 79
Cdd:TIGR00934  46 IAVHYFYIISLTIIASILLY-PSTVKNP-AYIDALFLAAGALTQGGLNTVDMND-LSLYQQIVLYILMLLTT 114
TrkG COG0168
Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];
11-96 1.30e-03

Trk-type K+ transport system, membrane component [Inorganic ion transport and metabolism];


Pssm-ID: 439938 [Multi-domain]  Cd Length: 414  Bit Score: 40.84  E-value: 1.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612905144  11 YLMLFFSTTIIGALLLYLpFTGkkpISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTV-TLLT 89
Cdd:COG0168  331 FFFLYLLLVVVGTLLLSL-TEG---LDFLTALFEVASAFGNVGLSLGITGASLSDAGKLVLIFLMLLGRLEILTVlVLLT 406

                 ....*..
gi 612905144  90 LVFLNRK 96
Cdd:COG0168  407 PRFRWRE 413
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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