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Conserved domains on  [gi|612903813|gb|EZV15517|]
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hypothetical protein U926_02628 [Staphylococcus aureus 12S00881]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3183 COG3183
Predicted restriction endonuclease, HNH family [Defense mechanisms];
11-123 1.04e-39

Predicted restriction endonuclease, HNH family [Defense mechanisms];


:

Pssm-ID: 442416 [Multi-domain]  Cd Length: 112  Bit Score: 128.58  E-value: 1.04e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612903813  11 ELENTEYVEGKPYVQYGIKYERNQALRNEAIKIHGTTCKVCGFDFKAKYGDLGEGFIEIHHLKPMFSIKrEIKVNPQKDL 90
Cdd:COG3183    2 LEEPKGFTEGAKKEVTHKRYERNPKLRKKAKEHAGGKCEVCGFDFEFVYGELGEGYIEVHHLIPLSEIG-EGGVDPIEDL 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 612903813  91 VPLCSNCHKMIHRnTKKPLTIKELTKIVNYNSK 123
Cdd:COG3183   81 VPLCPNCHRMLHR-GRPPLSIEELKKLLKRRKA 112
 
Name Accession Description Interval E-value
COG3183 COG3183
Predicted restriction endonuclease, HNH family [Defense mechanisms];
11-123 1.04e-39

Predicted restriction endonuclease, HNH family [Defense mechanisms];


Pssm-ID: 442416 [Multi-domain]  Cd Length: 112  Bit Score: 128.58  E-value: 1.04e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612903813  11 ELENTEYVEGKPYVQYGIKYERNQALRNEAIKIHGTTCKVCGFDFKAKYGDLGEGFIEIHHLKPMFSIKrEIKVNPQKDL 90
Cdd:COG3183    2 LEEPKGFTEGAKKEVTHKRYERNPKLRKKAKEHAGGKCEVCGFDFEFVYGELGEGYIEVHHLIPLSEIG-EGGVDPIEDL 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 612903813  91 VPLCSNCHKMIHRnTKKPLTIKELTKIVNYNSK 123
Cdd:COG3183   81 VPLCPNCHRMLHR-GRPPLSIEELKKLLKRRKA 112
HNHc cd00085
HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic ...
 39-102 1.10e-04

HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and anaredoxins.


Pssm-ID: 238038 [Multi-domain]  Cd Length: 57  Bit Score: 37.45  E-value: 1.10e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 612903813  39 EAIKIHGTTCKVCGFDFKAKYgdlgegfIEIHHLKPmfsiKREIKVNPQKDLVPLCSNCHKMIH 102
Cdd:cd00085    5 LVLLARDGLCPYCGKPGGTEG-------LEVDHIIP----LSDGGNNDLDNLVLLCRKCHRKKH 57
HNH pfam01844
HNH endonuclease; His-Asn-His (HNH) proteins are a very common family of small nucleic ...
 48-103 6.76e-03

HNH endonuclease; His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity.


Pssm-ID: 396422 [Multi-domain]  Cd Length: 47  Bit Score: 32.71  E-value: 6.76e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 612903813   48 CKVCGFDFKakygdlGEGFIEIHHLKPmfsIKREIKVNPQkDLVPLCSNCHKMIHR 103
Cdd:pfam01844   1 CQYCGRPFH------ISDALTVDHIIP---LSDGGADDIE-NLILLCPSCHNKKHN 46
 
Name Accession Description Interval E-value
COG3183 COG3183
Predicted restriction endonuclease, HNH family [Defense mechanisms];
11-123 1.04e-39

Predicted restriction endonuclease, HNH family [Defense mechanisms];


Pssm-ID: 442416 [Multi-domain]  Cd Length: 112  Bit Score: 128.58  E-value: 1.04e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612903813  11 ELENTEYVEGKPYVQYGIKYERNQALRNEAIKIHGTTCKVCGFDFKAKYGDLGEGFIEIHHLKPMFSIKrEIKVNPQKDL 90
Cdd:COG3183    2 LEEPKGFTEGAKKEVTHKRYERNPKLRKKAKEHAGGKCEVCGFDFEFVYGELGEGYIEVHHLIPLSEIG-EGGVDPIEDL 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 612903813  91 VPLCSNCHKMIHRnTKKPLTIKELTKIVNYNSK 123
Cdd:COG3183   81 VPLCPNCHRMLHR-GRPPLSIEELKKLLKRRKA 112
HNHc cd00085
HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic ...
 39-102 1.10e-04

HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and anaredoxins.


Pssm-ID: 238038 [Multi-domain]  Cd Length: 57  Bit Score: 37.45  E-value: 1.10e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 612903813  39 EAIKIHGTTCKVCGFDFKAKYgdlgegfIEIHHLKPmfsiKREIKVNPQKDLVPLCSNCHKMIH 102
Cdd:cd00085    5 LVLLARDGLCPYCGKPGGTEG-------LEVDHIIP----LSDGGNNDLDNLVLLCRKCHRKKH 57
HNH pfam01844
HNH endonuclease; His-Asn-His (HNH) proteins are a very common family of small nucleic ...
 48-103 6.76e-03

HNH endonuclease; His-Asn-His (HNH) proteins are a very common family of small nucleic acid-binding proteins that are generally associated with endonuclease activity.


Pssm-ID: 396422 [Multi-domain]  Cd Length: 47  Bit Score: 32.71  E-value: 6.76e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 612903813   48 CKVCGFDFKakygdlGEGFIEIHHLKPmfsIKREIKVNPQkDLVPLCSNCHKMIHR 103
Cdd:pfam01844   1 CQYCGRPFH------ISDALTVDHIIP---LSDGGADDIE-NLILLCPSCHNKKHN 46
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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