|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-427 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 808.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 1 MSSIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALL 80
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 81 KELDGLNERGIPT-SNLRISNRAQVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERL 159
Cdd:PRK01117 81 KEIDELEARGVDVrERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 160 LKSNIEYKQAYFKGMFNETCPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTS 239
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 240 SNPIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRR 319
Cdd:PRK01117 241 SNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAVR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 320 VSGITDLSINSIDVLTGLDTVKICTAYELDGKEITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKYLER 399
Cdd:PRK01117 321 VNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIKR 400
|
410 420
....*....|....*....|....*...
gi 612898698 400 ISELCNVQISIFSVGPDREQTNLLKELW 427
Cdd:PRK01117 401 IEELTGVPISIISTGPDRDQTIILRDPF 428
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
3-424 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 778.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 3 SIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLKE 82
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 83 LDGLNERGIPT-SNLRISNRAQVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLLK 161
Cdd:COG0104 81 IDGLEARGVDVrSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 162 SNIEYKQAYFKGMFNETCPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTSSN 241
Cdd:COG0104 161 ELLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 242 PIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRVS 321
Cdd:COG0104 241 TTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRIN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 322 GITDLSINSIDVLTGLDTVKICTAYELDGKEITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKYLERIS 401
Cdd:COG0104 321 GLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERIE 400
|
410 420
....*....|....*....|...
gi 612898698 402 ELCNVQISIFSVGPDREQTNLLK 424
Cdd:COG0104 401 ELLGVPISIVSVGPDREQTIVRR 423
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-420 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 744.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 5 VVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLKELD 84
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 85 GLNERGIP-TSNLRISNRAQVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLLKSN 163
Cdd:pfam00709 81 ELEERGIDvPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 164 IEYKQAYFKGMFNETcPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTSSNPI 243
Cdd:pfam00709 161 LELKNKLLEKLYGEP-LDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 244 AGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRVSGI 323
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 324 TDLSINSIDVLTGLDTVKICTAYELDGKEITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKYLERISEL 403
Cdd:pfam00709 320 TGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEEL 399
|
410
....*....|....*..
gi 612898698 404 CNVQISIFSVGPDREQT 420
Cdd:pfam00709 400 LGVPIKIISVGPDREQT 416
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
3-420 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 706.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 3 SIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLKE 82
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 83 LDGLNERGIP-TSNLRISNRAQVILPYHLAQDEYEERLRgdnkIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLLK 161
Cdd:smart00788 81 IEELEAKGVDvKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 162 SNIEYKQAYFKGMFNETCPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTSSN 241
Cdd:smart00788 157 ELLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 242 PIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRVS 321
Cdd:smart00788 237 TTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRIN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 322 GITDLSINSIDVLTGLDTVKICTAYELDGKEITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKYLERIS 401
Cdd:smart00788 317 GITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERIE 396
|
410
....*....|....*....
gi 612898698 402 ELCNVQISIFSVGPDREQT 420
Cdd:smart00788 397 ELVGVPVSIISTGPDREQT 415
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
5-425 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 587.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 5 VVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLKELD 84
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 85 GLNERGIPT-SNLRISNRAQVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLLKSN 163
Cdd:TIGR00184 81 YLEKRGISVrDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 164 IEYKQAYFKGMFNETCPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTSSNPI 243
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 244 AGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRVSGI 323
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 324 TDLSINSIDVLTGLDTVKICTAYELDGKEITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKYLERISEL 403
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEEL 400
|
410 420
....*....|....*....|..
gi 612898698 404 CNVQISIFSVGPDREQTNLLKE 425
Cdd:TIGR00184 401 TGVPVTIISTGPEREQTIDLRK 422
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
2-420 |
1.19e-174 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 490.47 E-value: 1.19e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 2 SSIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLK 81
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 82 ELDGLNERGIP-TSNLRISNRAQVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADlleketferll 160
Cdd:cd03108 81 EIEELEKKGIDvKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 161 ksnieykqayfkgmfnetcpsfddifeeyyaagqrlkEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTSS 240
Cdd:cd03108 150 -------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSS 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 241 NPIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRV 320
Cdd:cd03108 193 NTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRI 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 321 SGITDLSINSIDVltgldtvkictayeldgkeiteypanldqlkrckpifeelpgwtedvtsvrtleelpeNARKYLERI 400
Cdd:cd03108 273 NGLTELALTKLDV----------------------------------------------------------NAQKYIERI 294
|
410 420
....*....|....*....|
gi 612898698 401 SELCNVQISIFSVGPDREQT 420
Cdd:cd03108 295 EELLGVPITYISVGPDREQT 314
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
4-322 |
7.55e-35 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 130.95 E-value: 7.55e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 4 IVVVGTQWGDEGKGKITDFLAE--QSDVIARfSGGNNAGHT-IQFGGETYKLHLVPSGIFY-KDKLAVIGNGVVVDPVAL 79
Cdd:NF038379 2 DVVVDGQFGSTGKGLIAGYLAEraAPDVVVR-AAGPNAGHTyIDDEGRKFVHRMLPNGIVSpPLKQVLIGPGSEIDLEVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 80 LKELDGLNERGIPTSN-LRISNRAQVILPYHLAqdeyEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADlleketfer 158
Cdd:NF038379 81 REEIEELEDAGHDVGKrLLIHEQATVIELHKHV----EEEAGPMTKIGSTKKGIGAARAAKIRRNPSTLGD--------- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 159 llksnieYKQAYFKGMFNETCPSFDDIFEEYYAAgqrlkefvtdtskilDDAFVADEKVLFEGAQGVMLDIDHGTYPFVT 238
Cdd:NF038379 148 -------AEGDFGEGAVRDQPWEIAERVVDNALY---------------DFALQAAERIQIEGTQGYSLGLHAGFYPYCT 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 239 SSNPIAGNVTVGTGVGPTFV--SKVIGVCKAYTSRVGD-----GPFPTEL-FDEDGhhireVGREYGTTTGRPRRVGWFD 310
Cdd:NF038379 206 SRDCTPADFLADAGIPLPNVdaFKVVGTARTYPIRVAGwsgnsYPDQGETtWEELG-----LPEELTTVTKKVRRVGTFS 280
|
330
....*....|..
gi 612898698 311 SVVLRHSRRVSG 322
Cdd:NF038379 281 AEQVREAVQANG 292
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01117 |
PRK01117 |
adenylosuccinate synthetase; Provisional |
1-427 |
0e+00 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 234904 Cd Length: 430 Bit Score: 808.12 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 1 MSSIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALL 80
Cdd:PRK01117 1 MKNVVVVGTQWGDEGKGKIVDLLSERADVVVRFQGGHNAGHTLVIDGKKYKLHLIPSGILRPGKTCVIGNGVVLDPEALL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 81 KELDGLNERGIPT-SNLRISNRAQVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERL 159
Cdd:PRK01117 81 KEIDELEARGVDVrERLRISERAHLILPYHRALDKAREKARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPETFAEK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 160 LKSNIEYKQAYFKGMFNETCPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTS 239
Cdd:PRK01117 161 LEENLEYKNFLLTKYYGAEAVDFEEILDEYLEYAERLKPYVTDTSLLLNDALKAGKRVLFEGAQGTLLDIDHGTYPFVTS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 240 SNPIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRR 319
Cdd:PRK01117 241 SNTTAGGAATGSGVGPTKIDYVLGIAKAYTTRVGSGPFPTELFDEVGEHLRERGHEFGTTTGRPRRCGWFDAVALRYAVR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 320 VSGITDLSINSIDVLTGLDTVKICTAYELDGKEITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKYLER 399
Cdd:PRK01117 321 VNGLTGLALTKLDVLDGLEEIKICVAYELDGKRIDYFPASLEDLARCEPIYEELPGWSESTTGVRSFDDLPENARKYIKR 400
|
410 420
....*....|....*....|....*...
gi 612898698 400 ISELCNVQISIFSVGPDREQTNLLKELW 427
Cdd:PRK01117 401 IEELTGVPISIISTGPDRDQTIILRDPF 428
|
|
| PurA |
COG0104 |
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is ... |
3-424 |
0e+00 |
|
Adenylosuccinate synthase [Nucleotide transport and metabolism]; Adenylosuccinate synthase is part of the Pathway/BioSystem: Purine biosynthesis
Pssm-ID: 439874 Cd Length: 423 Bit Score: 778.81 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 3 SIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLKE 82
Cdd:COG0104 1 NVVVVGAQWGDEGKGKIVDLLAERADVVVRFQGGNNAGHTVVVGGKKFKLHLIPSGILRPGKTCVIGNGVVLDPEALLEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 83 LDGLNERGIPT-SNLRISNRAQVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLLK 161
Cdd:COG0104 81 IDGLEARGVDVrSRLRISERAHLILPYHRALDKAREEARGKKKIGTTGRGIGPAYEDKVARRGIRVGDLLDPEVLREKLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 162 SNIEYKQAYFKGMFNETCPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTSSN 241
Cdd:COG0104 161 ELLEYKNFLLEKLYGAEPLDFEELLEEYLEYAERLKPYVADTSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 242 PIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRVS 321
Cdd:COG0104 241 TTAGGACTGSGVGPTKIDRVIGVVKAYTTRVGEGPFPTELFDETGERLRERGHEFGTTTGRPRRCGWLDAVALRYAVRIN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 322 GITDLSINSIDVLTGLDTVKICTAYELDGKEITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKYLERIS 401
Cdd:COG0104 321 GLTGLALTKLDVLDGLDEIKVCVAYELDGERIDEFPASLEDLARCEPVYEELPGWKEDISGIRSFEDLPENARAYVERIE 400
|
410 420
....*....|....*....|...
gi 612898698 402 ELCNVQISIFSVGPDREQTNLLK 424
Cdd:COG0104 401 ELLGVPISIVSVGPDREQTIVRR 423
|
|
| Adenylsucc_synt |
pfam00709 |
Adenylosuccinate synthetase; |
5-420 |
0e+00 |
|
Adenylosuccinate synthetase;
Pssm-ID: 459912 Cd Length: 417 Bit Score: 744.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 5 VVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLKELD 84
Cdd:pfam00709 1 VVVGAQWGDEGKGKIVDLLAEDADVVVRFQGGNNAGHTVVVDGKKYKLHLLPSGILNPGKTNVIGNGVVIDPPALLEEIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 85 GLNERGIP-TSNLRISNRAQVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLLKSN 163
Cdd:pfam00709 81 ELEERGIDvPDRLFISDRAHLILPYHKALDGLREEARGKKKIGTTGRGIGPAYSDKAARRGIRVGDLLDPEVFREKLEAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 164 IEYKQAYFKGMFNETcPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTSSNPI 243
Cdd:pfam00709 161 LELKNKLLEKLYGEP-LDVEEELEELLEYAERLKPYVVDTSYFLNKALKEGKKILFEGAQGTLLDIDHGTYPYVTSSNTT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 244 AGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRVSGI 323
Cdd:pfam00709 240 AGGACTGLGIGPTKIDEVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGATTGRPRRCGWLDLVALRYAVRINGV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 324 TDLSINSIDVLTGLDTVKICTAYELDGKEITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKYLERISEL 403
Cdd:pfam00709 320 TGLALTKLDVLDGLDEIKVCVAYELDGKRIDYFPADLEDLEKVEPVYETLPGWKEDISGVRSFEDLPENARKYVEFIEEL 399
|
410
....*....|....*..
gi 612898698 404 CNVQISIFSVGPDREQT 420
Cdd:pfam00709 400 LGVPIKIISVGPDREQT 416
|
|
| Adenylsucc_synt |
smart00788 |
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine ... |
3-420 |
0e+00 |
|
Adenylosuccinate synthetase; Adenylosuccinate synthetase plays an important role in purine biosynthesis, by catalyzing the GTP-dependent conversion of IMP and aspartic acid to AMP. Adenylosuccinate synthetase has been characterized from various sources ranging from Escherichia coli (gene purA) to vertebrate tissues. In vertebrates, two isozymes are present - one involved in purine biosynthesis and the other in the purine nucleotide cycle. The crystal structure of adenylosuccinate synthetase from E. coli reveals that the dominant structural element of each monomer of the homodimer is a central beta-sheet of 10 strands. The first nine strands of the sheet are mutually parallel with right-handed crossover connections between the strands. The 10th strand is antiparallel with respect to the first nine strands. In addition, the enzyme has two antiparallel beta-sheets, comprised of two strands and three strands each, 11 alpha-helices and two short 3/10-helices. Further, it has been suggested that the similarities in the GTP-binding domains of the synthetase and the p21ras protein are an example of convergent evolution of two distinct families of GTP-binding proteins. Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana when compared with the known structures from E. coli reveals that the overall fold is very similar to that of the E. coli protein.
Pssm-ID: 197875 Cd Length: 417 Bit Score: 706.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 3 SIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLKE 82
Cdd:smart00788 1 VVVVVGAQWGDEGKGKIVDYLAEKADVVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNKKNVIGNGVVIDPEALFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 83 LDGLNERGIP-TSNLRISNRAQVILPYHLAQDEYEERLRgdnkIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLLK 161
Cdd:smart00788 81 IEELEAKGVDvKDRLFISDRAHLILPYHIALDKAREKAR----IGTTGRGIGPAYEDKVARRGIRVGDLFDEEVLREKLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 162 SNIEYKQAYFKGMFNETCPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTSSN 241
Cdd:smart00788 157 ELLDYKNFLLKKLYGAEPVDVEEILEELLEYAERLRPYVTDVSELLNEALKAGKKVLFEGAQGTLLDIDHGTYPYVTSSN 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 242 PIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRVS 321
Cdd:smart00788 237 TTAGGAATGAGIGPTRIDRVIGVVKAYTTRVGEGPFPTELFDETGEKLRERGHEFGTTTGRPRRCGWFDAVLLRYAVRIN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 322 GITDLSINSIDVLTGLDTVKICTAYELDGKEITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKYLERIS 401
Cdd:smart00788 317 GITGLALTKLDVLDGLDEIKVCVAYKLDGKIIDYFPADLEDLERCEPIYEELPGWKEDTTGVRSYEDLPENAKKYIERIE 396
|
410
....*....|....*....
gi 612898698 402 ELCNVQISIFSVGPDREQT 420
Cdd:smart00788 397 ELVGVPVSIISTGPDREQT 415
|
|
| purA |
TIGR00184 |
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, ... |
5-425 |
0e+00 |
|
adenylosuccinate synthase; Alternate name IMP--aspartate ligase. [Purines, pyrimidines, nucleosides, and nucleotides, Purine ribonucleotide biosynthesis]
Pssm-ID: 272949 Cd Length: 425 Bit Score: 587.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 5 VVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLKELD 84
Cdd:TIGR00184 1 VVVGGQWGDEGKGKIVDLLADKPDIVARYQGGHNAGHTIVIDGVKYGLHLIPSGFLYPDAKLLIGNGVVVDPEVLLKEME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 85 GLNERGIPT-SNLRISNRAQVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLLKSN 163
Cdd:TIGR00184 81 YLEKRGISVrDRLFVSYRCHLILPYHKKLDKAREKSKLAKKIGTTGKGIGPAYEDKVARSGLRVGDLLDDEAFAEKAKNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 164 IEYKQAYFKGMFNETCPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTSSNPI 243
Cdd:TIGR00184 161 LEYLNEQLVKYYKDEGVDYEKKLDEYMKYAEELKPFVVDVSVELNEALDEGEKVLFEGAQGTMLDIDYGTYPYVTSSNTT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 244 AGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRVSGI 323
Cdd:TIGR00184 241 AGGVATGVGIGPTKVDEVIGVFKAYTTRVGAGPFPTELSDEEGEKLGTKGAEFGTTTGRRRRCGWFDLVAARYACRLNGA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 324 TDLSINSIDVLTGLDTVKICTAYELDGKEITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKYLERISEL 403
Cdd:TIGR00184 321 TQLALTKLDVLDGIDEIKVCVAYRMKGEILELFPLDLKDLKGVEPIYETLPGWDKECTGVTEYSDLPENAKKYIERIEEL 400
|
410 420
....*....|....*....|..
gi 612898698 404 CNVQISIFSVGPDREQTNLLKE 425
Cdd:TIGR00184 401 TGVPVTIISTGPEREQTIDLRK 422
|
|
| PLN02513 |
PLN02513 |
adenylosuccinate synthase |
1-420 |
8.48e-179 |
|
adenylosuccinate synthase
Pssm-ID: 178129 Cd Length: 427 Bit Score: 505.33 E-value: 8.48e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 1 MSSIVVV-GTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFG-GETYKLHLVPSGIFYKDKLAVIGNGVVVDPVA 78
Cdd:PLN02513 1 LSQVSAVlGTQWGDEGKGKLVDILAQHFDIVARCQGGANAGHTIYNDeGKKFALHLVPSGILNEKTTCVIGNGVVVHLPG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 79 LLKELDGLNERGIP-TSNLRISNRAQVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFE 157
Cdd:PLN02513 81 LFEEIDGLESNGVScEGRLLVSDRAHLLFDFHQEVDGLREAELAGSKIGTTKRGIGPAYSSKATRNGLRVGDLRHMDTFA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 158 RLLKSNIEYKQAYFKGmFNETCPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFV 237
Cdd:PLN02513 161 EKLRELLADAAARFEG-FEYDASMVEEEVEAYKKFAERLEPFITDTVHYLNEAIQAGKKILVEGAQATMLDIDFGTYPFV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 238 TSSNPIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHS 317
Cdd:PLN02513 240 TSSNPSAGGICTGLGIAPRKLGDIIGVVKAYTTRVGSGPFPTELFGELGDLLREAGQEFGTTTGRPRRCGWLDIVALKYS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 318 RRVSGITDLSINSIDVLTGLDTVKICTAYEL-DGKEITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKY 396
Cdd:PLN02513 320 CQINGFTSLNLTKLDVLSGLPEIKIGVAYKTpDGKVVKSFPADLDTLEQVEVVYEVLPGWQEDISSVRNYDDLPAAAQAY 399
|
410 420
....*....|....*....|....
gi 612898698 397 LERISELCNVQISIFSVGPDREQT 420
Cdd:PLN02513 400 VERIEELVGVPVHYIGVGPGRDAL 423
|
|
| AdSS |
cd03108 |
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in ... |
2-420 |
1.19e-174 |
|
adenylosuccinate synthetase; Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the r-phosphate group of GTP is transferred to the 6-oxygen atom of IMP. An aspartate then displaces this 6-phosphate group to form the product adenylosuccinate. Because of its critical role in purine biosynthesis, AdSS is a target of antibiotics, herbicides and antitumor drugs.
Pssm-ID: 349762 Cd Length: 316 Bit Score: 490.47 E-value: 1.19e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 2 SSIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLK 81
Cdd:cd03108 1 KVTVVVGAQWGDEGKGKIVDYLAEKADIVVRFQGGNNAGHTVVVNGKKYKLHLLPSGILNPNATCVIGNGVVIDPPALFE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 82 ELDGLNERGIP-TSNLRISNRAQVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADlleketferll 160
Cdd:cd03108 81 EIEELEKKGIDvKGRLLISDRAHLVFPYHQELDGLEEKERGGKKIGTTKRGIGPAYADKAARTGIRVGD----------- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 161 ksnieykqayfkgmfnetcpsfddifeeyyaagqrlkEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTSS 240
Cdd:cd03108 150 -------------------------------------PYVVDTVELLNEALKAGKKVLFEGAQGTLLDIDFGTYPYVTSS 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 241 NPIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRV 320
Cdd:cd03108 193 NTTAGGVCTGLGIPPRRVDRVIGVVKAYTTRVGSGPFPTELFDEEGEKLRELGHEYGTTTGRPRRCGWLDLVALRYAVRI 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 321 SGITDLSINSIDVltgldtvkictayeldgkeiteypanldqlkrckpifeelpgwtedvtsvrtleelpeNARKYLERI 400
Cdd:cd03108 273 NGLTELALTKLDV----------------------------------------------------------NAQKYIERI 294
|
410 420
....*....|....*....|
gi 612898698 401 SELCNVQISIFSVGPDREQT 420
Cdd:cd03108 295 EELLGVPITYISVGPDREQT 314
|
|
| PTZ00350 |
PTZ00350 |
adenylosuccinate synthetase; Provisional |
5-420 |
1.41e-167 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 240376 Cd Length: 436 Bit Score: 477.21 E-value: 1.41e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 5 VVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLKELD 84
Cdd:PTZ00350 16 VILGAQWGDEGKGKLVDILSEKADIVARFNGGANAGHTIVVDGKKYALHLLPCGILYPNCINVLGNGVVIHLPSLLEEIE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 85 GLNERGIPTSN-LRISNRAQVILPYHLAQD--EYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLLK 161
Cdd:PTZ00350 96 QLTKKGINLLGrLYISDRAHLVFDLHQAIDgiQESEKGKGGTQIGTTKRGIGPCYSTKASRTGLRVGDLLNFETFEKKYR 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 162 SNIEYKQAYFKGMFNETcpsfDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTSSN 241
Cdd:PTZ00350 176 KLVEKLQEQYNIEEYDA----EEELERYKGYAEKLKDMIVDTVYFMNKAIKEGKRVLVEGANATMLDIDFGTYPYVTSSN 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 242 PIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRVS 321
Cdd:PTZ00350 252 TTVGGVCTGLGIPPNAIILVIGVVKAYTTRVGEGPFPTELFDENGDYLRKKGHEYGTTTGRPRRCGWLDIPALRYVQMIN 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 322 GITDLSINSIDVLTGLDTVKICTAYELDGK--EITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKYLER 399
Cdd:PTZ00350 332 GFDSINLTKLDVLSGLKEIKICVNYKNKGTglEIGRYPSSIEELEEYEPVYETMPGWKTDISKCKTFEELPENAQKYVLF 411
|
410 420
....*....|....*....|.
gi 612898698 400 ISELCNVQISIFSVGPDREQT 420
Cdd:PTZ00350 412 IEELLGVPIVWIGVGPNRENM 432
|
|
| PRK13786 |
PRK13786 |
adenylosuccinate synthetase; Provisional |
5-420 |
1.60e-156 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184325 Cd Length: 424 Bit Score: 448.87 E-value: 1.60e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 5 VVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYkDKLAVIGNGVVVDPVALLKELD 84
Cdd:PRK13786 4 IITGAQFGDEGKGKIVDLLAKDYDIVARFQGGDNAGHTVKVGDEVYKLHLIPSGFLL-DARVLIGPGVVLNPEVLAEEID 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 85 GLNERGIPTS--NLRISNRAQVILPYHLAQDEYEERLRgDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLLKS 162
Cdd:PRK13786 83 MLEKHGVKVDaeKLGIDAKTSIIMPYHIELDGLRESAR-TEKIGTTKRGIGFAYIDKIARDEVRMSDLVDKERLMRRLEE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 163 NIEYKQAYFKGMFNEtcPSF---DDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTS 239
Cdd:PRK13786 162 LAPQKEKEIKELGGD--PSIvrdEALIDKYLELGRQLAPYITDVSYEINKALDEGKSVLAEGAQGTHLDVIHGTQKFVTS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 240 SNPIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRR 319
Cdd:PRK13786 240 SSTIAGSACANLGVGPTRVDNVLGIVKAYITRVGEGPLPTELKDEAGEHLQDVGGEFGTTTGRPRRCGWFDLPLLKKAIY 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 320 VSGITDLSINSIDVLTGLDTVKICTAYELDGkEITEYPANL-DQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKYLE 398
Cdd:PRK13786 320 LNGYTEIALTKLDVLTGLDPIKICVGYELDG-EILDYPPELtSDLARCVPVYEELEGWSTDLTEVKAYEDLPENARNYVE 398
|
410 420
....*....|....*....|..
gi 612898698 399 RISELCNVQISIFSVGPDREQT 420
Cdd:PRK13786 399 RLEELMGVPIKYISVGPGREQT 420
|
|
| PRK13785 |
PRK13785 |
adenylosuccinate synthetase; Provisional |
3-420 |
2.11e-147 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237506 Cd Length: 454 Bit Score: 426.87 E-value: 2.11e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 3 SIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFyKDKLAVIGNGVVVDPVALLKE 82
Cdd:PRK13785 2 TVTIVGSQLGDEGKGGVVDLYGDAADVVVRYQGGDNAGHTVVHGGEEYKLSLVPSGAV-RGKIGVLGNGCVVNPETLFDE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 83 LDGLNERGIpTSNLRISNRAQVILPYHLAQDEYEERLRGDN--KIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLL 160
Cdd:PRK13785 81 IDALRERGL-DPDVRVAERAHVILPYHRVLDGIEEEAKSDSdlEVGTTGRGIGPTYEDKAGRRGVRVGDLLDPDVLRDRL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 161 KSNIEYKQAYFKGMFN----ETCPSFD--DIFEEYYAAGQRLKE--FVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHG 232
Cdd:PRK13785 160 EYVVPQKRALAEDVYGldasETPEAFDvdALFEEYREYGERLAEedMTVNAGDFLAERIDDGDNVMLEGAQGTSIDIDHG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 233 TYPFVTSSNPIAGNVTVGTGVGPTFVSK--VIGVCKAYTSRVGDGPFPTELFDEDGH---------------HIREVGRE 295
Cdd:PRK13785 240 NYPYVTSSNPTAGGAATGTGLGPTVVGQgeVVGIVKAYLSRVGSGPLPTELGGVEGDtpdeggrpdeeelatYIREEGGE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 296 YGTTTGRPRRVGWFDSVVLRHSRRVSGITDLSINSIDVLTGLDTVKICTAYELDGKEITEYPANLDQLKRCKPIFEELPG 375
Cdd:PRK13785 320 YGTVTGRPRRVGWLDMPMLRHAARASGFTGLAINHIDVLAGLDEVKVGHSYELDGEELLTMPATTERWARCEPNFRSFDG 399
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 612898698 376 WTE---DVTSVRTLEELPENARKYLERISELCNVQISIFSVGPDREQT 420
Cdd:PRK13785 400 WPEvdwAAVAEEGYDALPENARTYLEYVSDELDTPIYAVGVGPGREET 447
|
|
| PRK13788 |
PRK13788 |
adenylosuccinate synthetase; Provisional |
1-420 |
1.56e-141 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 184326 [Multi-domain] Cd Length: 404 Bit Score: 409.97 E-value: 1.56e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 1 MSSIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALL 80
Cdd:PRK13788 1 MPGIAIIGAQWGDEGKGKVVDALAPEADFVVRYQGGANAGHTVVAKGKTFKLNLLPSGVLHPHATSVLGDGMVIDPFRFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 81 KELDGLNERGIPtSNLRISNRAQVILPYHLAQDEyeerlrGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLE----KETF 156
Cdd:PRK13788 81 EERENLRAGGLN-PKLLISERAHLVLPHHKYVDG------RKNFVGTTGRGIGPAYSDRARRVGIRFGDLLDeavlRERV 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 157 ERLL--KSNIEYKQAYfkgmfnetcPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTY 234
Cdd:PRK13788 154 ERLLeaKPNSTREAGW---------DTVEKALADLAPMREILLPFIADTGSLLREAIREGKRVLFEGAQATLLDLNYGTY 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 235 PFVTSSNPIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVG----REYGTTTGRPRRVGWFD 310
Cdd:PRK13788 225 PYVTSSHPTVGGILVGAGVNHKAINKVYGVAKAFTTRVGHGPFPTEVFGEMAIRLRGKGgnpwDEFGTTTGRARRVGWLD 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 311 SVVLRHSRRVSGITDLSINSIDVLTGLDTVKICTAYELDGkeiteypanldqlkrcKPIFEELPGWTeDVTSVRTLEELP 390
Cdd:PRK13788 305 LVLLKYACEVNGFDGLVLTKLDVLSGLEKVKVCVEYDDDG----------------QPVYKELPGWG-DLDGVKSREALP 367
|
410 420 430
....*....|....*....|....*....|
gi 612898698 391 ENARKYLERISELCNVQISIFSVGPDREQT 420
Cdd:PRK13788 368 KEAQAYLELIEETTGVPVVMFSTSPRREDT 397
|
|
| PRK13783 |
PRK13783 |
adenylosuccinate synthetase; Provisional |
4-419 |
2.48e-140 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 237505 Cd Length: 404 Bit Score: 406.80 E-value: 2.48e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 4 IVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLKEL 83
Cdd:PRK13783 3 RVIVGLQWGDEGKGKVVTYLSRYYDIVVRYSGGANAGHTVNYGDFKVVHHLLPSADFKKNVGAAIGNGVVLDLEVLVEEL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 84 DGLNER--GIPtSNLRISNRAQVILPYHLAQDEYEERLRGdNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLLK 161
Cdd:PRK13783 83 EELKEKfpDYS-GRIFISELAHVVLPVHKELDEIIESVRK-NAIGTTKRGIGPAYADKVMRVGVRLADLFDEEKLREFLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 162 SNIE-YKQAYfkGMFNETCPSFDDIFEEYyaagQRLKEFVTDTSKILDdaFVADEKVLFEGAQGVMLDIDHGTYPFVTSS 240
Cdd:PRK13783 161 KILSlYKKLY--GIEFDVEKMMEDLLTFY----EKIKDLVVSPVEIKR--ILEEKSVLFEGTQGVLLDLDVGTYPYVTSS 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 241 NPIAGNVTVGTGVgPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRV 320
Cdd:PRK13783 233 NCSTTGVSAGMGF-PVKVDEVIGVFKAYTTRVGEGPFPTELFGEEGEKLRKAGHEYGATTGRPRRCGWLDLPLLRYAIEV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 321 SGITDLSINSIDVLTGLDTVKICTAYELDGKEITEyPANLDQLKRCKPIFEELPGWtEDVTSVrtleelpeNARKYLERI 400
Cdd:PRK13783 312 SGVDSLVMTKADVLNGFEKIKVCVRYEIGGKEVRD-PSSLRDLEKAEPVYEEFDGW-KSLEDK--------NFLKFVDFI 381
|
410
....*....|....*....
gi 612898698 401 SELCNVQISIFSVGPDREQ 419
Cdd:PRK13783 382 ERETGRKIAYISTGPKIEE 400
|
|
| PRK13787 |
PRK13787 |
adenylosuccinate synthetase; Provisional |
1-420 |
4.42e-139 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172324 Cd Length: 423 Bit Score: 404.33 E-value: 4.42e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 1 MSSIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALL 80
Cdd:PRK13787 1 MPASLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 81 KELDGLNERGIPTSN-LRISNRAQVILPYHLAQDEYEER-LRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKeTFER 158
Cdd:PRK13787 81 EECDRLQKEGFPVKDkLLLSDACHLLFPYHSQIDSARETtSSQEHKIGTTKKGIGICYADKMMRTGLRVGDLLDK-SYKR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 159 LLKSNIEYKQAYFKGMFNETCPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVT 238
Cdd:PRK13787 160 RLKHLVDEKNRELDKLYGMPPVSYNDINDGLKFFLSKVGKNIINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 239 SSNPIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSR 318
Cdd:PRK13787 240 SSNPTTGGALIGTGISFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEVLRQKGGEFGATTGRPRRCGWFDVEMLKHSV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 319 RVSGITDLSINSIDVLTGLDTVKICTAYELDGKEITEYPANldQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKYLE 398
Cdd:PRK13787 320 RINGITSIALTKIDILSDYDTIPVAVGYKLNGKTLDCFPSQ--GLEKVEPLYEEFPGWKDDISGINEFQKLPEKCKNYIS 397
|
410 420
....*....|....*....|..
gi 612898698 399 RISELCNVQISIFSVGPDREQT 420
Cdd:PRK13787 398 ALEKWIGVKINLVSTGPDRKDT 419
|
|
| PRK13784 |
PRK13784 |
adenylosuccinate synthetase; Provisional |
1-419 |
2.54e-118 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 172322 Cd Length: 428 Bit Score: 351.63 E-value: 2.54e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 1 MSSIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALL 80
Cdd:PRK13784 1 MSNIVIVGAQWGDEGKGKIADTLAEKADLVVRYQGGNNAGHTLVVNGKKTFLHLIPSGVLHQHTKCVIGHGVVLDPVALD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 81 KELDGLNERGIPTS--NLRISNRAQVILPYHLAQDEYEERlRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFER 158
Cdd:PRK13784 81 EEITRLQAKGIAISaeNLFVSESCTIITSYHKLLDAVRES-NTSEKIGTTGKGIGPAYEDKVSRKGIKFKHLFDKDLLRS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 159 LLKSNIEYKQAYFKGMFNETCPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVT 238
Cdd:PRK13784 160 RLAISLAEKETLFRDLYKVEYPTLEQEFDKLFALGQKLKQYAADTFSIIDQAIAAGKNVVYEGAQGVLLDVDYGTYPFVT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 239 SSNPIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSR 318
Cdd:PRK13784 240 SSNTSVAGVYSGATTAGHGLDHVIGITKAYTTRVGEGPFPTELFDDVGKFIQHKGGEIGVTTGRIRRCGWLDLPLLKYSA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 319 RVSGITDLSINSIDVLTGLDTVKICTAYELDGKEI-TEYPAnLDqLKRCKPIFEELPGWTEDvtSVRTLEELPENARKYL 397
Cdd:PRK13784 320 KCSNLTSIALTKVDVLSDMDTLKVCIGYKYEGKEIyCAYPG-ID-LYKVEPILVEMEPFSID--ETVTKDNMPAALKTYL 395
|
410 420
....*....|....*....|..
gi 612898698 398 ERISELCNVQISIFSVGPDREQ 419
Cdd:PRK13784 396 KTIENHVGIPISSLAYGPSREQ 417
|
|
| PRK04293 |
PRK04293 |
adenylosuccinate synthetase; Provisional |
1-420 |
4.24e-87 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 179812 Cd Length: 333 Bit Score: 268.29 E-value: 4.24e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 1 MSSIVVVGTQWGDEGKGKITDFLAEQS--DVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVA 78
Cdd:PRK04293 1 MTCTIVVGGFFGDEGKGKIIAYLALKDkpSIIARGGVGPNAGHTVEYNGKKYGLRMIPSGFVNKDAKLAIGAGVLVDPEV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 79 LLKELDGLNERGiptsNLRISNRAQVILPYHLAQDEYEERLRgdNKIGTTKKGIGPAYVDKVQRIGirmadlleketfer 158
Cdd:PRK04293 81 LLKEVEELNVGG----RVFVDYRCGIIEEKHVEEDRSDEHLS--KKIGSTGTGCGPANADRVLRRL-------------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 159 llksnieyKQAyfkgmfnetcpsfDDIFEeyyaagqrLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVT 238
Cdd:PRK04293 141 --------KLA-------------KDVEE--------LEKYLTDVPEEVNEALDRGENVLIEGTQGFGLSLYYGTYPYVT 191
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 239 SSNPIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVgrEYGTTTGRPRRVGWFDSVVLRHSR 318
Cdd:PRK04293 192 SKDTTASGIASDVGVGPTKVDEVIVVFKSYPTRVGEGPFPTELSLEEAEKLGLV--EYGTVTGRRRRVGPFDFELARRAA 269
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 319 RVSGITDLSInsidvlTGLDtvkictAYELDGKEITEYpanldqlkrckpifeelpgwtedvtsvrtlEELPENARKYLE 398
Cdd:PRK04293 270 RINGATQIAI------TKLD------KLDKEAYGVTEY------------------------------DKLPPEAKKFIE 307
|
410 420
....*....|....*....|..
gi 612898698 399 RISELCNVQISIFSVGPDREQT 420
Cdd:PRK04293 308 EIEEELGVPVTLISTGPELEDT 329
|
|
| amino_Aden_PurZ |
NF038379 |
succino-amino-deoxyadenylate synthase PurZ; |
4-322 |
7.55e-35 |
|
succino-amino-deoxyadenylate synthase PurZ;
Pssm-ID: 468496 Cd Length: 292 Bit Score: 130.95 E-value: 7.55e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 4 IVVVGTQWGDEGKGKITDFLAE--QSDVIARfSGGNNAGHT-IQFGGETYKLHLVPSGIFY-KDKLAVIGNGVVVDPVAL 79
Cdd:NF038379 2 DVVVDGQFGSTGKGLIAGYLAEraAPDVVVR-AAGPNAGHTyIDDEGRKFVHRMLPNGIVSpPLKQVLIGPGSEIDLEVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 80 LKELDGLNERGIPTSN-LRISNRAQVILPYHLAqdeyEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADlleketfer 158
Cdd:NF038379 81 REEIEELEDAGHDVGKrLLIHEQATVIELHKHV----EEEAGPMTKIGSTKKGIGAARAAKIRRNPSTLGD--------- 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 159 llksnieYKQAYFKGMFNETCPSFDDIFEEYYAAgqrlkefvtdtskilDDAFVADEKVLFEGAQGVMLDIDHGTYPFVT 238
Cdd:NF038379 148 -------AEGDFGEGAVRDQPWEIAERVVDNALY---------------DFALQAAERIQIEGTQGYSLGLHAGFYPYCT 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 239 SSNPIAGNVTVGTGVGPTFV--SKVIGVCKAYTSRVGD-----GPFPTEL-FDEDGhhireVGREYGTTTGRPRRVGWFD 310
Cdd:NF038379 206 SRDCTPADFLADAGIPLPNVdaFKVVGTARTYPIRVAGwsgnsYPDQGETtWEELG-----LPEELTTVTKKVRRVGTFS 280
|
330
....*....|..
gi 612898698 311 SVVLRHSRRVSG 322
Cdd:NF038379 281 AEQVREAVQANG 292
|
|
| PTZ00351 |
PTZ00351 |
adenylosuccinate synthetase; Provisional |
4-425 |
4.34e-18 |
|
adenylosuccinate synthetase; Provisional
Pssm-ID: 173544 Cd Length: 710 Bit Score: 86.64 E-value: 4.34e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 4 IVVVGTQWGDEGKGKITDFLAEQS--DVIARFSGGNNAGHTI-QFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALL 80
Cdd:PTZ00351 172 IMVAGAFFGDEGKGKTVDAVAHHPlcTCIARVNSGENAGHTVyDKAGRKFVFNLAPSGLLLPGKRNYIGPECVMDPVSFM 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 81 -KELDGLNERGIPTSNLRISNRAQVILPYHLAQDeyeerLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLL-EKETFER 158
Cdd:PTZ00351 252 eKEIIQLIDAGIDYRDRLFIGNVCIVTPYHKLLD-----LLGSAANSSTLKGMAPVHGSKVMKRGIRLDHIFnDDETLRK 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 159 LLKSNIEykqaYFKGMFNETCPSFDDIFE--------------EYYAAGQRLKEFVTDTSKILDD--------------- 209
Cdd:PTZ00351 327 RLEKDMD----TYLGLLKVKNLSDADVVRlcreensdgvvrvpDYVIAFAQAKDKVEFLVKLYRDrvrhnpdfparcdvt 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 210 -----AFVADEKVLFEGAQGVMLDIDHGTY-PFVTSSNPIAGNVTVGTGVG-PTFVSKVIGVCKAY-TSRVGDGPFPTEL 281
Cdd:PTZ00351 403 yelhaAVLRGEKVLLEGPQSYWLSNARTKFwESTTSADTTAAGLLAASQLNfQKFKSVVLNVHKAPgSSRVGIGACPSSF 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 282 FDED---GHHIR---------------------------------------------EVGR----------------EYG 297
Cdd:PTZ00351 483 VPQDyfsAQNIKtlrdlpsatcanfeavqrtlfrdgfphsndkarhngimapveysdETGDynigvamaiasaqhhgECG 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 298 TTTGRPRRVGWFDSVVLRHSRRVSGiTDLSINSIDVLTGLDTVKICTA---YELDGKEIT----------------EYPA 358
Cdd:PTZ00351 563 AVTKKPRVCGFFDCVLQHEVNSIQG-PYLTISALDRGDEYDKVGVTIAyvyYNPEGKQVDvnghvykngdiiragdPVPS 641
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612898698 359 NlDQLKRCKPIFEELPGWTEDVTSV---RTLEELPENARKYLERISELCNVQISIFSVGPDREQTNLLKE 425
Cdd:PTZ00351 642 E-PALYHCHPIVKLIDGWRDNPIAAakrRRNAPLPRGVCELLSTIEYFTNCKILSIGNGPNGDDIIYLRQ 710
|
|
| |
