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Conserved domains on  [gi|612671443|gb|EZS87539|]
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hypothetical protein W470_01809 [Staphylococcus aureus VET0159R]

Protein Classification

BCCT family transporter( domain architecture ID 10003438)

BCCT (betaine-carnitine-choline transporter) family transporter shares the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]; energized by pmf-driven proton symport; similar to Bacillus subtilis glycine betaine transporter OpuD

CATH:  1.20.5.430
Gene Ontology:  GO:0022857|GO:0071705|GO:0016020
PubMed:  20923416
TCDB:  2.A.15

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
1-505 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440903  Cd Length: 512  Bit Score: 643.35  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443   1 MNSSSPENPNGKKYSPVFIYSAIVVAIVVLLGAFLPEQFNYVTNNIKMWITEKLGWYYLILTTIIVFFCIFLIFSPIGKL 80
Cdd:COG1292    1 MSDKNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  81 KLGKPNDKPEFNTISWFAMLFSAGMGIGLVFYGAAEPMAHFATPP-TADPKTTEAYTEALRSTFFHWGFHAWAVYGVVAL 159
Cdd:COG1292   81 RLGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPpGVEPGSPEAARWAMAYTFFHWGLHAWAIYALVGL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 160 ALAYSQFRKGEPGLLSRTLRPLLGDKVEGPIGIFIDVLSVFATIVGVAVSLGMGALQINGGLHYLFNVPNNTFVQAIIII 239
Cdd:COG1292  161 ALAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 240 VVTILFIASAWSGLSKGIQYLSNLNIGLGTILMVAALIVGPTVLILNMLTSSTGSLLNTFLFNSFDTAALNPqkREWMSS 319
Cdd:COG1292  241 VITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGG 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 320 WTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPAIVSFVWFSVFGVLGI----ETGKKHKEIFDMTPETQLFG 395
Cdd:COG1292  319 WTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIhlelNGGGDLAEAVAAGVEAALFA 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 396 VFNHVPFGIVLSLIALLLIASFFITSADSATFVLGMQTTFGSLNPSSMVKVVWGISQALIAFVLLLAGGgngaeaLNAIQ 475
Cdd:COG1292  399 LLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGG------LSALQ 472
                        490       500       510
                 ....*....|....*....|....*....|
gi 612671443 476 SAAIISAFPFSFVVILMMVSFYKDANQERK 505
Cdd:COG1292  473 TASIITALPFSFVLLLMCVSLVKALREDPR 502
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
1-505 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 643.35  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443   1 MNSSSPENPNGKKYSPVFIYSAIVVAIVVLLGAFLPEQFNYVTNNIKMWITEKLGWYYLILTTIIVFFCIFLIFSPIGKL 80
Cdd:COG1292    1 MSDKNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  81 KLGKPNDKPEFNTISWFAMLFSAGMGIGLVFYGAAEPMAHFATPP-TADPKTTEAYTEALRSTFFHWGFHAWAVYGVVAL 159
Cdd:COG1292   81 RLGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPpGVEPGSPEAARWAMAYTFFHWGLHAWAIYALVGL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 160 ALAYSQFRKGEPGLLSRTLRPLLGDKVEGPIGIFIDVLSVFATIVGVAVSLGMGALQINGGLHYLFNVPNNTFVQAIIII 239
Cdd:COG1292  161 ALAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 240 VVTILFIASAWSGLSKGIQYLSNLNIGLGTILMVAALIVGPTVLILNMLTSSTGSLLNTFLFNSFDTAALNPqkREWMSS 319
Cdd:COG1292  241 VITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGG 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 320 WTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPAIVSFVWFSVFGVLGI----ETGKKHKEIFDMTPETQLFG 395
Cdd:COG1292  319 WTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIhlelNGGGDLAEAVAAGVEAALFA 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 396 VFNHVPFGIVLSLIALLLIASFFITSADSATFVLGMQTTFGSLNPSSMVKVVWGISQALIAFVLLLAGGgngaeaLNAIQ 475
Cdd:COG1292  399 LLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGG------LSALQ 472
                        490       500       510
                 ....*....|....*....|....*....|
gi 612671443 476 SAAIISAFPFSFVVILMMVSFYKDANQERK 505
Cdd:COG1292  473 TASIITALPFSFVLLLMCVSLVKALREDPR 502
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
17-503 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 608.77  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443   17 VFIYSAIVVAIVVLLGAFLPEQFNYVTNNIKMWITEKLGWYYLILTTIIVFFCIFLIFSPIGKLKLGKPNDKPEFNTISW 96
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443   97 FAMLFSAGMGIGLVFYGAAEPMAHFAT-PPTADPKTTEAYTEALRSTFFHWGFHAWAVYGVVALALAYSQFRKGEPGLLS 175
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  176 RTLRPLLGDKVEGPIGIFIDVLSVFATIVGVAVSLGMGALQINGGLHYLFNVPNNTFVQAIIIIVVTILFIASAWSGLSK 255
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  256 GIQYLSNLNIGLGTILMVAALIVGPTVLILNMLTSSTGSLLNTFLFNSFDTAALNPQKrEWMSSWTLYYWGWWLSWSPFV 335
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGDTG-GWLGGWTIFYWAWWIAWAPFV 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  336 GVFIARVSKGRSIREFISGVLLVPAIVSFVWFSVFGVLGIETGKKHK----EIFDMTPETQLFGVFNHVPFGIVLSLIAL 411
Cdd:pfam02028 320 GMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPgdlaDAVEAGPPAALFALLEQLPLGTILSVLAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  412 LLIASFFITSADSATFVLGMQTTFGSLNPSSMVKVVWGISQALIAFVLLLAGGgngaeaLNAIQSAAIISAFPFSFVVIL 491
Cdd:pfam02028 400 LLIIIFFVTSADSGTLVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGG------LEALQSASIIAALPFSFILLL 473
                         490
                  ....*....|..
gi 612671443  492 MMVSFYKDANQE 503
Cdd:pfam02028 474 MCISLFKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
55-503 3.48e-159

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 461.44  E-value: 3.48e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443   55 GWYYLILTTIIVFFCIFLIFSPIGKLKLGKPNDKPEFNTISWFAMLFSAGMGIGLVFYGAAEPMAHFATPPT-ADPKTTE 133
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFgAGPTSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  134 AYTEALRSTFFHWGFHAWAVYGVVALALAYSQFRKGEPGLLSRTLRPLLGDKVEGPIGIFIDVLSVFATIVGVAVSLGMG 213
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  214 ALQINGGLHYLFNVPNNTFVQAIIIIVVTILFIASAWSGLSKGIQYLSNLNIGLGTILMVAALIVGPTVLILNMLTSSTG 293
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  294 SLLNTFLFNSFDTAAlNPQKREWMSSWTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPAIVSFVWFSVFGVL 373
Cdd:TIGR00842 241 NYLQNFPQMSFRTDP-DDGKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNS 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  374 GIETGKKH-----KEIFDMTPETQLFGVFNHVPFGIVLSLIALLLIASFFITSADSATFVLG-MQTTFGSLN--PSSMVK 445
Cdd:TIGR00842 320 ALLLQQNGgfingPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLAnTTSRGGQLGeePPKWVR 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 612671443  446 VVWGISQALIAFVLLLAGGgngaeALNAIQSAAIISAFPFSFVVILMMVSFYKDANQE 503
Cdd:TIGR00842 400 VFWAVAIGLIALVLLFSGG-----SLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK09928 PRK09928
choline transport protein BetT; Provisional
1-498 1.60e-126

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 385.59  E-value: 1.60e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443   1 MNSSSPENPNGKKYSPVFIY-SAIVVAIVVLLGAFLPEQFNYVTNNIKMWITEKLGWYYLILTTIIVFFCIFLIFSPIGK 79
Cdd:PRK09928   2 VMTDLSHKREKDRINPVVFYtSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGS 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  80 LKLGKPNDKPEFNTISWFAMLFSAGMGIGLVFYGAAEPMAHFATPPTADPKTTEAYTEALRSTFFHWGFHAWAVYGVVAL 159
Cdd:PRK09928  82 IKLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGM 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 160 ALAYSQFRKGEPGLLSRTLRPLLGDKVEGPIGIFIDVLSVFATIVGVAVSLGMGALQINGGLHYLFNVPNNTFVQAIIII 239
Cdd:PRK09928 162 ALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIA 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 240 VVTILFIASAWSGLSKGIQYLSNLNIGLGTILMVAALIVGPTVLILNMLTSSTGSLLNTFLFNSFDTAALNPQKrEWMSS 319
Cdd:PRK09928 242 LSVIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPT-EWMNN 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 320 WTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPAIVSFVWFSVFGVLGIETGKKHKEIFDMT----PETQLFG 395
Cdd:PRK09928 321 WTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIHGNAAFAEEamahPERGFYS 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 396 VFNHVPFGIVLSLIALLLIASFFITSADSATFVLGMQTT-FGSLNPSSMV--KVVWGISQALIAFVLLLAGGgngaeaLN 472
Cdd:PRK09928 401 LLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSkLKDINSDAPNwlRVFWSVAIGLLTLGMLMTNG------IS 474
                        490       500
                 ....*....|....*....|....*.
gi 612671443 473 AIQSAAIISAFPFSFVVILMMVSFYK 498
Cdd:PRK09928 475 ALQNTTVIMGLPFSFVIFFVMAGLYK 500
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
1-505 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 643.35  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443   1 MNSSSPENPNGKKYSPVFIYSAIVVAIVVLLGAFLPEQFNYVTNNIKMWITEKLGWYYLILTTIIVFFCIFLIFSPIGKL 80
Cdd:COG1292    1 MSDKNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKI 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  81 KLGKPNDKPEFNTISWFAMLFSAGMGIGLVFYGAAEPMAHFATPP-TADPKTTEAYTEALRSTFFHWGFHAWAVYGVVAL 159
Cdd:COG1292   81 RLGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPpGVEPGSPEAARWAMAYTFFHWGLHAWAIYALVGL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 160 ALAYSQFRKGEPGLLSRTLRPLLGDKVEGPIGIFIDVLSVFATIVGVAVSLGMGALQINGGLHYLFNVPNNTFVQAIIII 239
Cdd:COG1292  161 ALAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 240 VVTILFIASAWSGLSKGIQYLSNLNIGLGTILMVAALIVGPTVLILNMLTSSTGSLLNTFLFNSFDTAALNPqkREWMSS 319
Cdd:COG1292  241 VITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWLGG 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 320 WTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPAIVSFVWFSVFGVLGI----ETGKKHKEIFDMTPETQLFG 395
Cdd:COG1292  319 WTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIhlelNGGGDLAEAVAAGVEAALFA 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 396 VFNHVPFGIVLSLIALLLIASFFITSADSATFVLGMQTTFGSLNPSSMVKVVWGISQALIAFVLLLAGGgngaeaLNAIQ 475
Cdd:COG1292  399 LLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGG------LSALQ 472
                        490       500       510
                 ....*....|....*....|....*....|
gi 612671443 476 SAAIISAFPFSFVVILMMVSFYKDANQERK 505
Cdd:COG1292  473 TASIITALPFSFVLLLMCVSLVKALREDPR 502
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
17-503 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 608.77  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443   17 VFIYSAIVVAIVVLLGAFLPEQFNYVTNNIKMWITEKLGWYYLILTTIIVFFCIFLIFSPIGKLKLGKPNDKPEFNTISW 96
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443   97 FAMLFSAGMGIGLVFYGAAEPMAHFAT-PPTADPKTTEAYTEALRSTFFHWGFHAWAVYGVVALALAYSQFRKGEPGLLS 175
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  176 RTLRPLLGDKVEGPIGIFIDVLSVFATIVGVAVSLGMGALQINGGLHYLFNVPNNTFVQAIIIIVVTILFIASAWSGLSK 255
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  256 GIQYLSNLNIGLGTILMVAALIVGPTVLILNMLTSSTGSLLNTFLFNSFDTAALNPQKrEWMSSWTLYYWGWWLSWSPFV 335
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGDTG-GWLGGWTIFYWAWWIAWAPFV 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  336 GVFIARVSKGRSIREFISGVLLVPAIVSFVWFSVFGVLGIETGKKHK----EIFDMTPETQLFGVFNHVPFGIVLSLIAL 411
Cdd:pfam02028 320 GMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPgdlaDAVEAGPPAALFALLEQLPLGTILSVLAL 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  412 LLIASFFITSADSATFVLGMQTTFGSLNPSSMVKVVWGISQALIAFVLLLAGGgngaeaLNAIQSAAIISAFPFSFVVIL 491
Cdd:pfam02028 400 LLIIIFFVTSADSGTLVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGG------LEALQSASIIAALPFSFILLL 473
                         490
                  ....*....|..
gi 612671443  492 MMVSFYKDANQE 503
Cdd:pfam02028 474 MCISLFKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
55-503 3.48e-159

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 461.44  E-value: 3.48e-159
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443   55 GWYYLILTTIIVFFCIFLIFSPIGKLKLGKPNDKPEFNTISWFAMLFSAGMGIGLVFYGAAEPMAHFATPPT-ADPKTTE 133
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFgAGPTSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  134 AYTEALRSTFFHWGFHAWAVYGVVALALAYSQFRKGEPGLLSRTLRPLLGDKVEGPIGIFIDVLSVFATIVGVAVSLGMG 213
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  214 ALQINGGLHYLFNVPNNTFVQAIIIIVVTILFIASAWSGLSKGIQYLSNLNIGLGTILMVAALIVGPTVLILNMLTSSTG 293
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  294 SLLNTFLFNSFDTAAlNPQKREWMSSWTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPAIVSFVWFSVFGVL 373
Cdd:TIGR00842 241 NYLQNFPQMSFRTDP-DDGKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNS 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  374 GIETGKKH-----KEIFDMTPETQLFGVFNHVPFGIVLSLIALLLIASFFITSADSATFVLG-MQTTFGSLN--PSSMVK 445
Cdd:TIGR00842 320 ALLLQQNGgfingPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLAnTTSRGGQLGeePPKWVR 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 612671443  446 VVWGISQALIAFVLLLAGGgngaeALNAIQSAAIISAFPFSFVVILMMVSFYKDANQE 503
Cdd:TIGR00842 400 VFWAVAIGLIALVLLFSGG-----SLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK09928 PRK09928
choline transport protein BetT; Provisional
1-498 1.60e-126

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 385.59  E-value: 1.60e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443   1 MNSSSPENPNGKKYSPVFIY-SAIVVAIVVLLGAFLPEQFNYVTNNIKMWITEKLGWYYLILTTIIVFFCIFLIFSPIGK 79
Cdd:PRK09928   2 VMTDLSHKREKDRINPVVFYtSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGS 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  80 LKLGKPNDKPEFNTISWFAMLFSAGMGIGLVFYGAAEPMAHFATPPTADPKTTEAYTEALRSTFFHWGFHAWAVYGVVAL 159
Cdd:PRK09928  82 IKLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGM 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 160 ALAYSQFRKGEPGLLSRTLRPLLGDKVEGPIGIFIDVLSVFATIVGVAVSLGMGALQINGGLHYLFNVPNNTFVQAIIII 239
Cdd:PRK09928 162 ALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIA 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 240 VVTILFIASAWSGLSKGIQYLSNLNIGLGTILMVAALIVGPTVLILNMLTSSTGSLLNTFLFNSFDTAALNPQKrEWMSS 319
Cdd:PRK09928 242 LSVIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPT-EWMNN 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 320 WTLYYWGWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPAIVSFVWFSVFGVLGIETGKKHKEIFDMT----PETQLFG 395
Cdd:PRK09928 321 WTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIHGNAAFAEEamahPERGFYS 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 396 VFNHVPFGIVLSLIALLLIASFFITSADSATFVLGMQTT-FGSLNPSSMV--KVVWGISQALIAFVLLLAGGgngaeaLN 472
Cdd:PRK09928 401 LLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSkLKDINSDAPNwlRVFWSVAIGLLTLGMLMTNG------IS 474
                        490       500
                 ....*....|....*....|....*.
gi 612671443 473 AIQSAAIISAFPFSFVVILMMVSFYK 498
Cdd:PRK09928 475 ALQNTTVIMGLPFSFVIFFVMAGLYK 500
PRK03356 PRK03356
L-carnitine/gamma-butyrobetaine antiport BCCT transporter;
17-500 3.27e-71

L-carnitine/gamma-butyrobetaine antiport BCCT transporter;


Pssm-ID: 179568  Cd Length: 504  Bit Score: 236.55  E-value: 3.27e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  17 VFIYSAIVVAIVVLLGAFLPEQFNYVTNNIKMWITEKLGWYYLILTTIIVFFCIFLIFSPIGKLKLGkpNDKPEFNTISW 96
Cdd:PRK03356  14 VFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLG--DEKPEFSTASW 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  97 FAMLFSAGMGIGLVFYGAAEPMAHFATPP-TADPKTTEAYTEALRSTFFHWGFHAWAVYGVVALALAYSQF-RKGEPGLL 174
Cdd:PRK03356  92 IFMMFASCTSAAVLFWGSIEIYYYISTPPfGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFGYFFFvRKMDVIRP 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 175 SRTLRPLLGDK-VEGPIGIFIDVLSVFATIVGVAVSLGMGALQINGGLHYLFNVPNNTFVQAIIIIVVTILFIASAWSGL 253
Cdd:PRK03356 172 SSTLVPLVGEKhAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGL 251
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 254 SKGIQYLSNLNIGLGTILMVAALIVGPTVLILNMLTSSTGSLLNTFLFNSFDTAALNpqKREWMSSWTLYYWGWWLSWSP 333
Cdd:PRK03356 252 QKGVRIASDVRSYLSFLMLGWVFIVGGTSFIMNYFTDSVGMLLMYLPRMLFYTDPIG--KGGFPQGWTVFYWAWWVIYAI 329
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 334 FVGVFIARVSKGRSIREFISGVLLVPAIVSFVWFSVFGVLGIETgkKHKEIFDMTPETQLFGVFNHV-------PFGIVL 406
Cdd:PRK03356 330 QMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLL--MDKNIINIPNLIEQYGVARAIietwaalPLSTAT 407
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 407 SLIALLLIASFFITSADSATFVLGMQTTFGSL---NPSSMVKVVWGISQALIAFVLLLAGGgngaeaLNAIQSAAIISAF 483
Cdd:PRK03356 408 MWGFFILCFIATVTLINACSYTLAMSTCREVRdgeEPPLLVRIGWSILVGIIGIVLLALGG------LKPIQTAIIAGGC 481
                        490
                 ....*....|....*..
gi 612671443 484 PFSFVVILMMVSFYKDA 500
Cdd:PRK03356 482 PLFFVNIMVTLSFIKDA 498
PRK09950 PRK09950
putative transporter; Provisional
8-503 1.70e-65

putative transporter; Provisional


Pssm-ID: 236636  Cd Length: 506  Bit Score: 221.20  E-value: 1.70e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443   8 NPNGKKYSPVFIYSAIVVAIVVLLGAFLPEQFNYVTNNIKMWITEKLGWYYLILTTIIVFFCIFLIFSPIGKLKLGKpnD 87
Cdd:PRK09950   3 NNKKKKDKPLISTSLLAVFFIVAALSLFPQQSAAAANTIFQWVTRTFGSPVQLFVLLAMILVLYLATSKYGNIRLGE--G 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443  88 KPEFNTISWFAMLFSAGMGIGLVFYGAAEPMAHFATPP-TADPKTTEAYTEALRSTFFHWGFHAWAVYGVVALALAYSQF 166
Cdd:PRK09950  81 KPEYSTLSWLFMFICAGLGSSTLYWGVMEWAYYYQTPGlNIAPRSPKALEYSVSYSFFHWGISAWATYALASLIMAYHFH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 167 RKGEPGL-LSRTLRPLLGDKVEGPIGIFIDVLSVFATIVGVAVSLGMGALQINGGLHYLFNVPNNTFVQAIIIIVVTILF 245
Cdd:PRK09950 161 VRKNKGLsLSGIIAAITGVKPQGPWGRLVDLMFLIATVGALTISLVVTAATFTRGLSALTGLPNNFTVQAFVILLSGVIF 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 246 IASAWSGLSKGIQYLSNLNIGLGTILMVAALIVGPTVLILNMLTSSTGSLLNTFLFNSFDTAALNPQKreWMSSWTLYYW 325
Cdd:PRK09950 241 CLSSYIGIDNGLQRLSKMVGWGAFLFALLVLIVGPTEFITNNIINSIGLTTQNFLQMSLFTDPMGDGS--FTRNWTVFYW 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 326 GWWLSWSPFVGVFIARVSKGRSIREFISGVLLVPAIvsFVWFsVFGVLgiETGKKHKEIF----------DMTPETQLFG 395
Cdd:PRK09950 319 LWWISYTPGVAMFVTRVSRGRKIKEVIWGLILGSSV--GCWF-FFGVL--ESYAIHQFINgvinvpqilnTLGGETAVQQ 393
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612671443 396 VFNHVPFGIVLSLIALLLIASFFITSADSATFVLGMQTTFG---SLNPSSMVKVVWGISQALIAFVLLLAGGgngaeALN 472
Cdd:PRK09950 394 LLSSLPAGKLFLAAYLGIMIIFLASHMDAVAYTMAATSTRNlreGDDPDRGLRLFWCVVITLIPLSILFTGA-----SLD 468
                        490       500       510
                 ....*....|....*....|....*....|.
gi 612671443 473 AIQSAAIISAFPFSFVVILMMVSFYKDANQE 503
Cdd:PRK09950 469 TMKTTVVLTALPFLVILLIKVYGFIRWLKQD 499
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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