NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|612670673|gb|EZS86779|]
View 

hypothetical protein W470_01993 [Staphylococcus aureus VET0159R]

Protein Classification

DUF2188 domain-containing protein( domain architecture ID 10008902)

DUF2188 domain-containing protein similar to Bacillus subtilis YdaT

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DUF2188 super family cl23970
Uncharacterized protein conserved in bacteria (DUF2188); This domain represents a ...
 1-107 5.80e-32

Uncharacterized protein conserved in bacteria (DUF2188); This domain represents a ribosome-associating protein predicted to mediate translation inhibition alongside repair of DNA damage or restriction in conflict contexts. A subset of this family contains a conserved histidine residue, raising the possibility that it directly acts as a RNase or in RNA end-processing.


The actual alignment was detected with superfamily member COG4876:

Pssm-ID: 474116  Cd Length: 122  Bit Score: 109.85  E-value: 5.80e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612670673   1 MPFTMKGYPEKWKEFEVIKRQKAIEIANAMLKEGYLEKDVVPIAAKKAKDWYRALSKEEIKALEEENFVQFHTATMEkte 80
Cdd:COG4876    1 MPWTMNDYPASMKNLDPLVRKKAIEIANALLDEGYDEGRAIPIATEQAKEWYRNASKEEEKELKKEDNPQKRDDHDS--- 77

                         90       100
                 ....*....|....*....|....*..
gi 612670673  81 vdseyatTDNEEHIQEQSNQDKSYFDS 107
Cdd:COG4876   78 -------PELLDEDVEVYYEDDGWKVK 97
 
Name Accession Description Interval E-value
YdaT COG4876
Uncharacterized conserved protein YdaT [Function unknown];
1-107 5.80e-32

Uncharacterized conserved protein YdaT [Function unknown];


Pssm-ID: 443904  Cd Length: 122  Bit Score: 109.85  E-value: 5.80e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612670673   1 MPFTMKGYPEKWKEFEVIKRQKAIEIANAMLKEGYLEKDVVPIAAKKAKDWYRALSKEEIKALEEENFVQFHTATMEkte 80
Cdd:COG4876    1 MPWTMNDYPASMKNLDPLVRKKAIEIANALLDEGYDEGRAIPIATEQAKEWYRNASKEEEKELKKEDNPQKRDDHDS--- 77

                         90       100
                 ....*....|....*....|....*..
gi 612670673  81 vdseyatTDNEEHIQEQSNQDKSYFDS 107
Cdd:COG4876   78 -------PELLDEDVEVYYEDDGWKVK 97
 
Name Accession Description Interval E-value
YdaT COG4876
Uncharacterized conserved protein YdaT [Function unknown];
1-107 5.80e-32

Uncharacterized conserved protein YdaT [Function unknown];


Pssm-ID: 443904  Cd Length: 122  Bit Score: 109.85  E-value: 5.80e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612670673   1 MPFTMKGYPEKWKEFEVIKRQKAIEIANAMLKEGYLEKDVVPIAAKKAKDWYRALSKEEIKALEEENFVQFHTATMEkte 80
Cdd:COG4876    1 MPWTMNDYPASMKNLDPLVRKKAIEIANALLDEGYDEGRAIPIATEQAKEWYRNASKEEEKELKKEDNPQKRDDHDS--- 77

                         90       100
                 ....*....|....*....|....*..
gi 612670673  81 vdseyatTDNEEHIQEQSNQDKSYFDS 107
Cdd:COG4876   78 -------PELLDEDVEVYYEDDGWKVK 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH