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Conserved domains on  [gi|612660564|gb|EZS76830|]
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ATP synthase subunit A [Staphylococcus aureus VET0191R]

Protein Classification

FoF1 ATP synthase subunit a( domain architecture ID 10012597)

FoF1 ATP synthase subunit a is part of the membrane proton channel of the F-type ATPase that produces ATP from ADP in the presence of a proton gradient across the membrane; it plays a direct role in the translocation of protons across the membrane

Gene Ontology:  GO:0045263|GO:0046933|GO:0005886
PubMed:  28001127

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 6-242 4.09e-66

F0F1 ATP synthase subunit A; Validated


:

Pssm-ID: 235617  Cd Length: 227  Bit Score: 204.26  E-value: 4.09e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564   6 PLVSWNLFGFDIVfnlSSILMILVTAFLVFLLAIICTRNLKKRPTGKQNFVEWIFDFVRGIIEGNMaWKKGGQFHFLAVT 85
Cdd:PRK05815   3 HHLIIGFGGFNFD---SLLLSVLLGVLILLLFALVATRKLSGVPGGLQNFVEMIVEFVRGQVKDNI-GGKGKKFAPLAFT 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  86 LILYIFIANMLGLPFsivtkdhtLWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKG-YVQPFWPLAIINVFEE 164
Cdd:PRK05815  79 LFLFILLMNLLGLIP--------YLLFPPTADINVTLALALIVFVLVIYYGIKKKGLGGYLKEfYLQPHPLLLPIEIISE 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 612660564 165 FTSTLTLGLRLYGNIFAGEILLTLLAGLFFNePAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKVADEH 242
Cdd:PRK05815 151 FSRPISLSLRLFGNMLAGELILALIALLGGA-GLLLALAPLILPVAWTIFEIFVGTLQAYIFMMLTIVYISMAVEEEH 227
 
Name Accession Description Interval E-value
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 6-242 4.09e-66

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 204.26  E-value: 4.09e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564   6 PLVSWNLFGFDIVfnlSSILMILVTAFLVFLLAIICTRNLKKRPTGKQNFVEWIFDFVRGIIEGNMaWKKGGQFHFLAVT 85
Cdd:PRK05815   3 HHLIIGFGGFNFD---SLLLSVLLGVLILLLFALVATRKLSGVPGGLQNFVEMIVEFVRGQVKDNI-GGKGKKFAPLAFT 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  86 LILYIFIANMLGLPFsivtkdhtLWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKG-YVQPFWPLAIINVFEE 164
Cdd:PRK05815  79 LFLFILLMNLLGLIP--------YLLFPPTADINVTLALALIVFVLVIYYGIKKKGLGGYLKEfYLQPHPLLLPIEIISE 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 612660564 165 FTSTLTLGLRLYGNIFAGEILLTLLAGLFFNePAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKVADEH 242
Cdd:PRK05815 151 FSRPISLSLRLFGNMLAGELILALIALLGGA-GLLLALAPLILPVAWTIFEIFVGTLQAYIFMMLTIVYISMAVEEEH 227
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 23-240 2.06e-61

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 191.83  E-value: 2.06e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  23 SILMILVTAFLVFLLAIICTRNLKKRPTGKQNFVEWIFDFVRGIIEGNMAwKKGGQFHFLAVTLILYIFIANMLGLPFsi 102
Cdd:COG0356    2 TVLMSWLAMLLLLLLFLLATRKLKLVPGGLQNFVEMLVEFVRNQVKDTIG-KKGRKFAPLLLTLFLFILVSNLLGLIP-- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564 103 vtkdhtlWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKG-YVQPFWPLA----IINVFEEFTSTLTLGLRLYG 177
Cdd:COG0356   79 -------GLFPPTADINVTLALALIVFVLVHYYGIKKKGLGGYLKHlFFPPFPWLAplmlPIEIISELARPLSLSLRLFG 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 612660564 178 NIFAGEILLTLLAGLFFNepAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKVAD 240
Cdd:COG0356  152 NMFAGHIILLLLAGLAPF--LLLGVLSLLLPVAWTAFELLVGFLQAYIFTMLTAVYISLAVEE 212
ATP-synt_A pfam00119
ATP synthase A chain;
24-235 2.24e-54

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 173.83  E-value: 2.24e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564   24 ILMILVTAFLVFLLAIICTRNLKK-RPTGKQNFVEWIFDFVRGIIEGNMAWKKGGQFHFLAVTLILYIFIANMLGLPFSi 102
Cdd:pfam00119   1 LLMSLIVALILLLFLLLATRKTKKlVPGRLQNFVEMLVEFVDNIVKDNIGKKKGRKFFPLLLTLFFFILVSNLLGLIPK- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  103 vtkdhTLWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKGYVQPFWP------LAIINVFEEFTSTLTLGLRLY 176
Cdd:pfam00119  80 -----SPGGFTVTADINVTLALALIVFLLVHYYGIKKHGLGGYFKKLFVPPVPlplvplLLPIEIISEFARPVSLSLRLF 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 612660564  177 GNIFAGEILLTLLAGL---FFNEPAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMS 235
Cdd:pfam00119 155 GNMLAGHLLLLLLAGLifaLLSAGFLLGVIPPLLGVAWTLFELLVAFIQAYVFTMLTAVYIS 216
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 17-238 6.86e-33

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 118.85  E-value: 6.86e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564   17 IVFNLSSILMILVTAFLVFLLAIICTRNLKkrPTGKQNFVEWIFDFVRGIIEGNMaWKKGGQFHFLAVTLILYIFIANML 96
Cdd:TIGR01131  11 TLFSLTLLSLILLLSLLIFLISSSLSRWLI--PSRWQNLMESIYEFVLSIVKSQI-GGKKGKFFPLIFTLFLFILISNLL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564   97 GLPFsivtkdhtlWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTK--QYLKGYVQPFWP---LAIINVFEEFTSTLTL 171
Cdd:TIGR01131  88 GLIP---------YSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGflAHLVPSGTPLPLipfLVIIETISYLARPISL 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 612660564  172 GLRLYGNIFAGEILLTLLAGLFFNEPAWGWI-ISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKV 238
Cdd:TIGR01131 159 SVRLFANISAGHLLLTLLSGLLFSLMSSAIFaLLLLILVALIILEIFVAFIQAYVFTLLTCLYLNDAL 226
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 82-235 7.15e-30

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 109.03  E-value: 7.15e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  82 LAVTLILYIFIANMLGLpfsivtkdhTLWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLK-----GYVQPFWPL 156
Cdd:cd00310    7 LLGTLFLFILFSNLLGL---------IPYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHflppgTPLPLAPLM 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 612660564 157 AIINVFEEFTSTLTLGLRLYGNIFAGEILLTLLAGLFFNEPAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMS 235
Cdd:cd00310   78 VPIELISELIRPLSLSVRLFANMFAGHLLLALLSGLVPSLLSSVGLLPLLLPVALTLLELFVAFIQAYVFTLLTAVYIS 156
 
Name Accession Description Interval E-value
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 6-242 4.09e-66

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 204.26  E-value: 4.09e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564   6 PLVSWNLFGFDIVfnlSSILMILVTAFLVFLLAIICTRNLKKRPTGKQNFVEWIFDFVRGIIEGNMaWKKGGQFHFLAVT 85
Cdd:PRK05815   3 HHLIIGFGGFNFD---SLLLSVLLGVLILLLFALVATRKLSGVPGGLQNFVEMIVEFVRGQVKDNI-GGKGKKFAPLAFT 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  86 LILYIFIANMLGLPFsivtkdhtLWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKG-YVQPFWPLAIINVFEE 164
Cdd:PRK05815  79 LFLFILLMNLLGLIP--------YLLFPPTADINVTLALALIVFVLVIYYGIKKKGLGGYLKEfYLQPHPLLLPIEIISE 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 612660564 165 FTSTLTLGLRLYGNIFAGEILLTLLAGLFFNePAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKVADEH 242
Cdd:PRK05815 151 FSRPISLSLRLFGNMLAGELILALIALLGGA-GLLLALAPLILPVAWTIFEIFVGTLQAYIFMMLTIVYISMAVEEEH 227
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 23-240 2.06e-61

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 191.83  E-value: 2.06e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  23 SILMILVTAFLVFLLAIICTRNLKKRPTGKQNFVEWIFDFVRGIIEGNMAwKKGGQFHFLAVTLILYIFIANMLGLPFsi 102
Cdd:COG0356    2 TVLMSWLAMLLLLLLFLLATRKLKLVPGGLQNFVEMLVEFVRNQVKDTIG-KKGRKFAPLLLTLFLFILVSNLLGLIP-- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564 103 vtkdhtlWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKG-YVQPFWPLA----IINVFEEFTSTLTLGLRLYG 177
Cdd:COG0356   79 -------GLFPPTADINVTLALALIVFVLVHYYGIKKKGLGGYLKHlFFPPFPWLAplmlPIEIISELARPLSLSLRLFG 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 612660564 178 NIFAGEILLTLLAGLFFNepAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKVAD 240
Cdd:COG0356  152 NMFAGHIILLLLAGLAPF--LLLGVLSLLLPVAWTAFELLVGFLQAYIFTMLTAVYISLAVEE 212
ATP-synt_A pfam00119
ATP synthase A chain;
24-235 2.24e-54

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 173.83  E-value: 2.24e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564   24 ILMILVTAFLVFLLAIICTRNLKK-RPTGKQNFVEWIFDFVRGIIEGNMAWKKGGQFHFLAVTLILYIFIANMLGLPFSi 102
Cdd:pfam00119   1 LLMSLIVALILLLFLLLATRKTKKlVPGRLQNFVEMLVEFVDNIVKDNIGKKKGRKFFPLLLTLFFFILVSNLLGLIPK- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  103 vtkdhTLWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKGYVQPFWP------LAIINVFEEFTSTLTLGLRLY 176
Cdd:pfam00119  80 -----SPGGFTVTADINVTLALALIVFLLVHYYGIKKHGLGGYFKKLFVPPVPlplvplLLPIEIISEFARPVSLSLRLF 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 612660564  177 GNIFAGEILLTLLAGL---FFNEPAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMS 235
Cdd:pfam00119 155 GNMLAGHLLLLLLAGLifaLLSAGFLLGVIPPLLGVAWTLFELLVAFIQAYVFTMLTAVYIS 216
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 17-238 6.86e-33

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 118.85  E-value: 6.86e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564   17 IVFNLSSILMILVTAFLVFLLAIICTRNLKkrPTGKQNFVEWIFDFVRGIIEGNMaWKKGGQFHFLAVTLILYIFIANML 96
Cdd:TIGR01131  11 TLFSLTLLSLILLLSLLIFLISSSLSRWLI--PSRWQNLMESIYEFVLSIVKSQI-GGKKGKFFPLIFTLFLFILISNLL 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564   97 GLPFsivtkdhtlWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTK--QYLKGYVQPFWP---LAIINVFEEFTSTLTL 171
Cdd:TIGR01131  88 GLIP---------YSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGflAHLVPSGTPLPLipfLVIIETISYLARPISL 158

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 612660564  172 GLRLYGNIFAGEILLTLLAGLFFNEPAWGWI-ISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKV 238
Cdd:TIGR01131 159 SVRLFANISAGHLLLTLLSGLLFSLMSSAIFaLLLLILVALIILEIFVAFIQAYVFTLLTCLYLNDAL 226
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 82-235 7.15e-30

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 109.03  E-value: 7.15e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  82 LAVTLILYIFIANMLGLpfsivtkdhTLWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLK-----GYVQPFWPL 156
Cdd:cd00310    7 LLGTLFLFILFSNLLGL---------IPYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHflppgTPLPLAPLM 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 612660564 157 AIINVFEEFTSTLTLGLRLYGNIFAGEILLTLLAGLFFNEPAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMS 235
Cdd:cd00310   78 VPIELISELIRPLSLSVRLFANMFAGHLLLALLSGLVPSLLSSVGLLPLLLPVALTLLELFVAFIQAYVFTLLTAVYIS 156
atpI CHL00046
ATP synthase CF0 A subunit
 10-233 2.26e-24

ATP synthase CF0 A subunit


Pssm-ID: 176987  Cd Length: 228  Bit Score: 96.54  E-value: 2.26e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  10 WNLFGFDivFNLSSILMILVTAFLVFLLAIICTRNLKKRPTGKQNFVEWIFDFVRGIIEGNMAWKKGGQFHFLAVTLILY 89
Cdd:CHL00046  14 WQIGGFQ--VHGQVLITSWVVIAILLGSALLATRNLQTIPTGGQNFFEYVLEFIRDLAKTQIGEEEYRPWVPFIGTMFLF 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  90 IFIANMLG--LPFSIVTKDHTLwWKSPTAD--ATVTLTLSTTIillTHFY-GIKMRGTKqYLKGYVQPFWPLAIINVFEE 164
Cdd:CHL00046  92 IFVSNWSGalLPWKLIELPHGE-LAAPTNDinTTVALALLTSV---AYFYaGLSKKGLG-YFGKYIQPTPILLPINILED 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 612660564 165 FTSTLTLGLRLYGNIFAGEILLTLLAGLFfnePAwgwIISIPGLivwqAFSIFVGTIQAYIFIMLSMVY 233
Cdd:CHL00046 167 FTKPLSLSFRLFGNILADELVVAVLVSLV---PL---VVPIPVM----FLGLFTSGIQALIFATLAAAY 225
PRK13421 PRK13421
F0F1 ATP synthase subunit A; Provisional
 29-242 3.30e-22

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237383  Cd Length: 223  Bit Score: 90.91  E-value: 3.30e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  29 VTAFLVfLLAIICTRNLKKRPTGKQNFVEWIFDFVRGIIEGNMAwKKGGQFHFLAVTLILYIFIANMLGLPFSIvtkdht 108
Cdd:PRK13421  29 IMAVLA-AGSALATRRLSLAPGRLQSVLELVVTTIDAQIRDTMQ-TDPAPYRALIGTLFLFVLVANWSSLVPGV------ 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564 109 lwwKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKGYVQPFWPLAIINVFEEFTSTLTLGLRLYGNIFAGEILLtl 188
Cdd:PRK13421 101 ---EPPTAHLETDAALALIVFLATIYYGVRARGVRGYLATFAEPTWVMIPLNLVEQLTRTFSLIVRLFGNVMSGVFVI-- 175

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 612660564 189 laglffnepawGWIISIPGLIV---WQAFSIFVGTIQAYIFIMLSMVYMSHKVADEH 242
Cdd:PRK13421 176 -----------GIVLSLAGLLVpipLMALDLLTGAVQAYIFAVLAMVFIGAAVSDDE 221
PRK13420 PRK13420
F0F1 ATP synthase subunit A; Provisional
 22-235 2.53e-21

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237382 [Multi-domain]  Cd Length: 226  Bit Score: 88.65  E-value: 2.53e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  22 SSILMILVTAFLVFLLAIICTRNLKKRPTGKQNFVEWIFDFVRGIIEGNMAWKKGGQFHFLAvTLILYIFIANMLGLpfs 101
Cdd:PRK13420  18 ESVLTTWGIMIVLVLASWLTTRRLSLDPGRFQVALEGVVSTIEDAIKEVLPRHARLVLPFVG-TLWIFILVANLIGL--- 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564 102 iVTKDHtlwwkSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKGYVQPFWPLAIINVFEEFTSTLTLGLRLYGNIFA 181
Cdd:PRK13420  94 -IPGFH-----SPTADLSVTAALALLVFFSVHWFGIRAEGLREYLKHYLSPSPFLLPFHLISEITRTLALAVRLFGNIMS 167

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 612660564 182 GEI---LLTLLAGLFfnepawgwiISIPGLIVwqafSIFVGTIQAYIFIMLSMVYMS 235
Cdd:PRK13420 168 LELaalLVLLVAGFL---------VPVPILML----HIIEALVQAYIFGMLALIYIA 211
PRK13419 PRK13419
F0F1 ATP synthase subunit A; Provisional
 12-242 4.56e-17

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237381  Cd Length: 342  Bit Score: 79.02  E-value: 4.56e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  12 LFGFDIVFNLSSILMILVTAFL--VFLLAIICTRNLKKR--PTGKQNFVEWIFDFVRGIIEGNMAWKKGGQFHFLAVTLI 87
Cdd:PRK13419  99 VGGFDISITKHVVMMWIASAILlvVFLAAGRKYKKMTKSqaPKGLANAMEALVEFIRLDVAKSNIGHGYEKFLPYLLTVF 178

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  88 LYIFIANMLGL-PFSivtkdhtlwwKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLK----GYVQPFWPLAI-INV 161
Cdd:PRK13419 179 FFILVCNLLGLvPYG----------ATATGNINVTLTLAVFTFFITQYAAIKAHGIKGYLAhltgGTHWSLWIIMIpIEF 248

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564 162 FEEFTSTLTLGLRLYGNIFAGEILLTLLAGLFF--NEPAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKVA 239
Cdd:PRK13419 249 IGLFTKPFALTVRLFANMTAGHIVILSLIFISFilKSYIVAVAVSVPFAIFIYLLELFVAFLQAYIFTMLSALFIGLATA 328


                 ...
gi 612660564 240 DEH 242
Cdd:PRK13419 329 HEG 331
ATP6 MTH00175
ATP synthase F0 subunit 6; Provisional
 17-239 1.84e-10

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177228  Cd Length: 244  Bit Score: 59.25  E-value: 1.84e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  17 IVFNLSSILMILVTAFLVFLLaiictRNLKKRPTGKQNFVEWIFDFVRGIIEGNMAwKKGGQFHFLAVTLILYIFIANML 96
Cdd:MTH00175  26 VTFTNSSMMMVLAVIIFWLLL-----KGDKLIPNRWQSIMELIYLNIRSVVHDNLG-KSGQKYFPFILSLFLFIAILNIL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  97 GLPFSIVTkdhtlwwksPTADATVTLTLSTTIILlthfyGIKMRGTKQYLKGYVQPFWP----------LAIINVFEEFT 166
Cdd:MTH00175 100 GLFPYVFT---------PTAHIIITFGLSLSIII-----AVTLLGFLTFKWNFLSILMPggaplvlapfLVLIETLSYLI 165

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 612660564 167 STLTLGLRLYGNIFAGEILLTLLAGLFFNEPAWGWIIS--IPGLIVW--QAFSIFVGTIQAYIFIMLSMVYMSHKVA 239
Cdd:MTH00175 166 RAISLGVRLAANISAGHLLFAILSGFAFNMLSNGLIILslFPMLIMIfiTLLEMAVAVIQAYVFCLLTTIYLGDTIA 242
ATP6 MTH00172
ATP synthase F0 subunit 6; Provisional
 17-234 3.99e-10

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214447  Cd Length: 232  Bit Score: 58.13  E-value: 3.99e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  17 IVFNLSSILMILVTAFLVFLLaiictRNLKKRPTGKQNFVEWIFDFVRGIIEGNMAwKKGGQFHFLAVTLILYIFIANML 96
Cdd:MTH00172  15 IGLTNSSIMMILVIIVVLLLF-----KGIKLIPKRWQSIIEIIYNHFHGVVKDNLG-NEGLKYFPFIISLFFFIVFLNLL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  97 GLPFSIVTkdhtlwwksPTADATVTLTLSTTIILlthfyGIKMRGTKQYLKGYVQPFWP----------LAIINVFEEFT 166
Cdd:MTH00172  89 GLFPYVFT---------PTTHIVVTLGLSFSIII-----GVTLAGFWRFKWDFFSILMPsgaplglaplLVLIETVSYIS 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 612660564 167 STLTLGLRLYGNIFAGEILLTLLAGLFFNEPAWGWIISIPGLIVWQAFSIF---VGTIQAYIFIMLSMVYM 234
Cdd:MTH00172 155 RAISLGVRLAANLSAGHLLFAILAGFGFNMLCASGFLSLFPLLIMVFITLLeiaVAVIQAYVFCLLTTIYL 225
PRK13417 PRK13417
F0F1 ATP synthase subunit A; Provisional
 24-234 1.09e-08

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237380  Cd Length: 352  Bit Score: 54.51  E-value: 1.09e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  24 ILMILVTAFLVFLLAI----ICTRNLKKRPTGKQNFVEWIFDFVR-GIIEGNMAWKKGGQFHFLaVTLILYIFIANMLGL 98
Cdd:PRK13417  98 VTMMWIVAFFLFLIFIpaanIIAKNPLKVQSRFANTVEVFVNFLRkDIVDESMHGHGHSYYHYI-FTLFFFILFCNLMGL 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  99 PFSI-----VTKD--------------HTLWW-------KSPTADATVTLTLSTTIILLTHFYGIKMRGTK----QYLKG 148
Cdd:PRK13417 177 VPSVgeltvVASDygglvalgvmdhtpHALPTfakvwsgITVTGDISVTMTLALLTMFLIYGAGFSYQGPKfiwhSVPNG 256

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564 149 YVQPFWPL--AIINVFEEFTSTLTLGLRLYGNIFAGEILLTLLAGLFFNEPAWGWI-ISIPGLIVWQAFSIFVGTIQAYI 225
Cdd:PRK13417 257 VPLLLYPImwPLEFIVSPMAKTFALTVRLLANMTAGHVIILALMGFIFQFQSWGIVpVSVIGSGLIYVLEIFVAFLQAYI 336


                 ....*....
gi 612660564 226 FIMLSMVYM 234
Cdd:PRK13417 337 FVLLTSLFV 345
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 79-235 1.32e-06

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214441  Cd Length: 223  Bit Score: 47.86  E-value: 1.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  79 FHFLAVTLILYIFIANMLGLPFSIVTkdhtlwwksPTADATVTLTLSTTIILLTHFYGIkMRGTKQYLKGYVQPFWPLAI 158
Cdd:MTH00157  68 STLIFISLFSFILFNNFLGLFPYIFT---------STSHLSLTLSLALPLWLSFMLFGW-INNTNHMFAHLVPQGTPPIL 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564 159 IN--VFEEFTSTL----TLGLRLYGNIFAGEILLTLLAGLFFNEPAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMV 232
Cdd:MTH00157 138 MPfmVLIETISNLirpgTLAVRLAANMIAGHLLLTLLGNTGPSLSSMILSILILIQILLLILESAVAIIQSYVFSVLSTL 217


                 ...
gi 612660564 233 YMS 235
Cdd:MTH00157 218 YSS 220
ATP6 MTH00173
ATP synthase F0 subunit 6; Provisional
 54-235 4.89e-06

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214448  Cd Length: 231  Bit Score: 46.01  E-value: 4.89e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  54 NFVEWIFDFVRGIIEGNMAWKKGGQFHFLaVTLILYIFIANMLGL-PFSivtkdhtlwwKSPTADATVTLTLSTTIILLT 132
Cdd:MTH00173  47 SVFKLFVLTVSSQVTRSSGLNLGGFSLLL-SSLFLFLISLNLSGLlPFV----------FSVTSHLAFTFSLALPLWLSL 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564 133 HFYGIkMRGTKQYLKGYVQPFWPLAIIN--VFEEFTSTL----TLGLRLYGNIFAGEILLTLLAG----LFFNEPAWGWI 202
Cdd:MTH00173 116 ILSGL-FYNPSKSLAGLVPAGAPAGLNPflVLIETVSILirplTLTVRLLANISAGHIVLTLIGNylssSLFSSSVVSLL 194

                        170       180       190
                 ....*....|....*....|....*....|...
gi 612660564 203 ISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMS 235
Cdd:MTH00173 195 LVLLIQVGYFIFEVAVMLIQAYIFTLLIKLYSD 227
ATP6 MTH00179
ATP synthase F0 subunit 6; Provisional
 15-234 9.06e-05

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177230  Cd Length: 227  Bit Score: 42.24  E-value: 9.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  15 FDIVFNLSSILMILVTAFLVFLLAIICTRNLKKRPTGKQNfveWIFDFVRGIIEGNMAwKKGGQFHFLAVTLILYIFIAN 94
Cdd:MTH00179   9 FESPSLLGIPLLALALLLPWLLFPSLTNRWLNNRLSTLQS---WFFGSFTFQLMQPIN-KKGHKWAVLFLSLMLFLLTLN 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  95 MLGL-PFSIvtkdhtlwwkSPTADATVTLTLSTTIILLTHFYGIKMR-----------GTKQYLkgyvQPFwpLAIINVF 162
Cdd:MTH00179  85 LLGLlPYTF----------TPTTQLSLNLGLALPLWLGTVLYGLFNQptialahllpeGTPTPL----IPM--LVWIETI 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 612660564 163 EEFTSTLTLGLRLYGNIFAGEILLTLLAGLFFNEPAWGWIISIPGLIVWQAFSIF---VGTIQAYIFIMLSMVYM 234
Cdd:MTH00179 149 SLLIRPLALGVRLTANITAGHLLMHLISSAVFVLMNFMGMVALLTLLVLFLLTLLevaVAMIQAYVFVLLLSLYL 223
ATP6 MTH00005
ATP synthase F0 subunit 6; Provisional
 79-242 7.68e-04

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 164583  Cd Length: 231  Bit Score: 39.72  E-value: 7.68e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  79 FHFLAVTLILYIFIANMLGL-PFSIVTKDHTLWwksptadaTVTLTLSTTI-ILLTHFYGIKMRGTKQYLKG----YVQP 152
Cdd:MTH00005  73 FSSLISALFTMIILMNLSGLlPYVFSTSSHLIF--------TLTLGLPLWLsLIMSSVTFSPKKFAAHLLPGgapdWLNP 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564 153 FwpLAIINVFEEFTSTLTLGLRLYGNIFAGEILLTLLaGLFFNEPAWGWIISIPGLIVWQAFSIF----VGTIQAYIFIM 228
Cdd:MTH00005 145 F--LVLIETISILVRPITLSFRLAANMSAGHIVLSLI-GIYAASALFSSISSTILLILTQMGYILfevgICLIQAYIFCL 221

                        170
                 ....*....|....
gi 612660564 229 LSMVYmshkvADEH 242
Cdd:MTH00005 222 LLSLY-----SDDH 230
ATP6 MTH00176
ATP synthase F0 subunit 6; Provisional
 113-235 7.78e-04

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214449  Cd Length: 229  Bit Score: 39.63  E-value: 7.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564 113 SPTADATVTLTLSTTIILLTHFYGIkMRGTKQYLKGYVQPFWPLAIIN--VFEEFTSTL----TLGLRLYGNIFAGEILL 186
Cdd:MTH00176  96 TSTSHLVITLSLALPLWLGVILSGF-INNFYSRLSHLVPQGTPPLLNPflVLIELVSLLirplTLAVRLAANLSAGHLLL 174

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 612660564 187 TLLAGLFFNE----PAWGWIISIPGlIVWQAFSIFVGTIQAYIFIMLSMVYMS 235
Cdd:MTH00176 175 GLLGAAMWGLlpvsPLIGFLLLIVQ-ILYFMFEIAVCMIQAYVFTLLLSLYLD 226
ATP6 MTH00035
ATP synthase F0 subunit 6; Validated
 158-235 6.62e-03

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177110  Cd Length: 229  Bit Score: 36.88  E-value: 6.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564 158 IINVFEEFTSTLTLGLRLYGNIFAGEILLTLLAG---LFFNEPAWGwIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYM 234
Cdd:MTH00035 147 WIETLSLFAQPIALGLRLAANLTAGHLLIFLLSTaiwELSNSPLIS-IITLIIFFLLFILEIGVACIQAYVFTALVHFYL 225


                 .
gi 612660564 235 S 235
Cdd:MTH00035 226 E 226
ATP6 MTH00174
ATP synthase F0 subunit 6; Provisional
 19-238 9.40e-03

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 133799  Cd Length: 252  Bit Score: 36.46  E-value: 9.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  19 FNLSSILMILVTAFLVFLLAIICTRNLKKRPTGKQNFVEWIFDFVRGIIEGNMAwKKGGQFHFLAVTLILYIFIANMLGL 98
Cdd:MTH00174  31 FCFTNTFFMMSFAVFLFYTIGAKGNNNTLVPNRILVGLELIYSHFYTVLKDNLG-NKGGNYLAFVLSLFILILFGNGLGL 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612660564  99 -PFSIVTKDHTLWWKSPTADATVTLTLSTTIILLTHFYGIKMrgtKQYLKGYVQPFwpLAIINVFEEFTSTLTLGLRLYG 177
Cdd:MTH00174 110 fPYVFTPTVHMVITLGLSFAIIVGTTLAGLITFRFNFFSILM---PQGAPLALAPL--LTIIETLSYISRAISLGVRLAA 184

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 612660564 178 NIFAGEILLTLLAG----LFFNEPAWGWIISIPGLIVWQAFSIFVGTIQAYIFIMLSMVYMSHKV 238
Cdd:MTH00174 185 NISSGHLLFSIIASfawkMINTGILIGSFVPFAILIFVTILEMAVAIIQAYVFTLLTIVYLRDTV 249
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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