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Conserved domains on  [gi|612272081|gb|EZQ65586|]
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hypothetical protein AF54_00404 [Serratia marcescens BIDMC 81]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 11447364)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
SCOP:  3000403

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
10-169 3.17e-27

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 100.46  E-value: 3.17e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612272081  10 RVDTDRLLIAPFTAADADDVYQAIT-PTLTRFMTFEPEaSPEDFANVWQSWLPLMREGEEVIFVARRREDRQFVGVGGAH 88
Cdd:COG1670    2 TLETERLRLRPLRPEDAEALAELLNdPEVARYLPGPPY-SLEEARAWLERLLADWADGGALPFAIEDKEDGELIGVVGLY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612272081  89 NL--RSPTPELGIWVKESLHGQGYGREIVQGIARWASERFQPPHFLYPVAEQNTASRRLVESLGGVLAG------KRENI 160
Cdd:COG1670   81 DIdrANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLEGtlrdalVIDGR 160

                 ....*....
gi 612272081 161 KYDAVVYHL 169
Cdd:COG1670  161 YRDHVLYSL 169
 
Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
10-169 3.17e-27

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 100.46  E-value: 3.17e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612272081  10 RVDTDRLLIAPFTAADADDVYQAIT-PTLTRFMTFEPEaSPEDFANVWQSWLPLMREGEEVIFVARRREDRQFVGVGGAH 88
Cdd:COG1670    2 TLETERLRLRPLRPEDAEALAELLNdPEVARYLPGPPY-SLEEARAWLERLLADWADGGALPFAIEDKEDGELIGVVGLY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612272081  89 NL--RSPTPELGIWVKESLHGQGYGREIVQGIARWASERFQPPHFLYPVAEQNTASRRLVESLGGVLAG------KRENI 160
Cdd:COG1670   81 DIdrANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLEGtlrdalVIDGR 160

                 ....*....
gi 612272081 161 KYDAVVYHL 169
Cdd:COG1670  161 YRDHVLYSL 169
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
15-150 4.45e-22

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 86.25  E-value: 4.45e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612272081   15 RLLIAPFTAADADDVYQ-AITPTLTRFMTFEPeASPEDFANVWQSWLPLMREGEEVIFVARRREDRqFVGVGGAHNL--R 91
Cdd:pfam13302   1 RLLLRPLTEEDAEALFElLSDPEVMRYGVPWP-LTLEEAREWLARIWAADEAERGYGWAIELKDTG-FIGSIGLYDIdgE 78
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 612272081   92 SPTPELGIWVKESLHGQGYGREIVQGIARWASERFQPPHFLYPVAEQNTASRRLVESLG 150
Cdd:pfam13302  79 PERAELGYWLGPDYWGKGYATEAVRALLEYAFEELGLPRLVARIDPENTASRRVLEKLG 137
 
Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
10-169 3.17e-27

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 100.46  E-value: 3.17e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612272081  10 RVDTDRLLIAPFTAADADDVYQAIT-PTLTRFMTFEPEaSPEDFANVWQSWLPLMREGEEVIFVARRREDRQFVGVGGAH 88
Cdd:COG1670    2 TLETERLRLRPLRPEDAEALAELLNdPEVARYLPGPPY-SLEEARAWLERLLADWADGGALPFAIEDKEDGELIGVVGLY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612272081  89 NL--RSPTPELGIWVKESLHGQGYGREIVQGIARWASERFQPPHFLYPVAEQNTASRRLVESLGGVLAG------KRENI 160
Cdd:COG1670   81 DIdrANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLEGtlrdalVIDGR 160

                 ....*....
gi 612272081 161 KYDAVVYHL 169
Cdd:COG1670  161 YRDHVLYSL 169
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
15-150 4.45e-22

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 86.25  E-value: 4.45e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612272081   15 RLLIAPFTAADADDVYQ-AITPTLTRFMTFEPeASPEDFANVWQSWLPLMREGEEVIFVARRREDRqFVGVGGAHNL--R 91
Cdd:pfam13302   1 RLLLRPLTEEDAEALFElLSDPEVMRYGVPWP-LTLEEAREWLARIWAADEAERGYGWAIELKDTG-FIGSIGLYDIdgE 78
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 612272081   92 SPTPELGIWVKESLHGQGYGREIVQGIARWASERFQPPHFLYPVAEQNTASRRLVESLG 150
Cdd:pfam13302  79 PERAELGYWLGPDYWGKGYATEAVRALLEYAFEELGLPRLVARIDPENTASRRVLEKLG 137
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
16-168 2.74e-09

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 53.07  E-value: 2.74e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612272081  16 LLIAPFTAADAD---DVYQAITPTLTrfMTFEPEASPEDFanvWQSWLPLMREGEEVIFVARrrEDRQFVGVGGAHNLRS 92
Cdd:COG1247    2 MTIRPATPEDAPaiaAIYNEAIAEGT--ATFETEPPSEEE---REAWFAAILAPGRPVLVAE--EDGEVVGFASLGPFRP 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612272081  93 P-----TPELGIWVKESLHGQGYGREIVQGIARWASERfqPPHFLYP-VAEQNTASRRLVESLGGVLAGKRENIKYDAVV 166
Cdd:COG1247   75 RpayrgTAEESIYVDPDARGRGIGRALLEALIERARAR--GYRRLVAvVLADNEASIALYEKLGFEEVGTLPEVGFKFGR 152

                 ..
gi 612272081 167 YH 168
Cdd:COG1247  153 WL 154
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
82-164 8.08e-07

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 44.90  E-value: 8.08e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612272081  82 VGVGGAHNLRSPTPEL-GIWVKESLHGQGYGREIVQGIARWASERFQPPHFLYpVAEQNTASRRLVESLGGVLAGKRENI 160
Cdd:COG3393    3 VAMAGVRAESPGVAEIsGVYTHPEYRGRGLASALVAALAREALARGARTPFLY-VDADNPAARRLYERLGFRPVGEYATV 81

                 ....
gi 612272081 161 KYDA 164
Cdd:COG3393   82 LFRK 85
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
40-150 4.22e-06

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 43.66  E-value: 4.22e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612272081   40 FMTFEPEASPEDFANVWQSWLplmREGEEVIFVARrrEDRQFVGVGGAHNLRSPTP---ELGIWVKESLHGQGYGREIVQ 116
Cdd:pfam00583   8 LSEEFPEPWPDEPLDLLEDWD---EDASEGFFVAE--EDGELVGFASLSIIDDEPPvgeIEGLAVAPEYRGKGIGTALLQ 82
                          90       100       110
                  ....*....|....*....|....*....|....
gi 612272081  117 GIARWASERFQPPHFLYpVAEQNTASRRLVESLG 150
Cdd:pfam00583  83 ALLEWARERGCERIFLE-VAADNLAAIALYEKLG 115
FR47 pfam08445
FR47-like protein; The members of this family are similar to the C-terminal region of the D. ...
90-158 4.64e-05

FR47-like protein; The members of this family are similar to the C-terminal region of the D. melanogaster hypothetical protein FR47. This protein has been found to consist of two N-acyltransferase-like domains swapped with the C-terminal strands.


Pssm-ID: 117022 [Multi-domain]  Cd Length: 86  Bit Score: 40.01  E-value: 4.64e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612272081   90 LRSPTPELG-IWVKESLHGQGYGREIVQGIARWASERFQPPhfLYPVAEQNTASRRLVESLGGVLAGKRE 158
Cdd:pfam08445  17 LRLPGGELGaLQTLPEHRRRGLGSRLVAALARGIAERGITP--FAVVVAGNTPSRRLYEKLGFRKIDETY 84
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
41-125 7.38e-05

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 40.75  E-value: 7.38e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612272081  41 MTFEPeASPEDFANVWQSWLPL-MREGEEVIFVARrrEDRQFVGVGGAHNLRSPTPELG-IWVKESLHGQGYGREIVQGI 118
Cdd:COG1246    1 MTIRP-ATPDDVPAILELIRPYaLEEEIGEFWVAE--EDGEIVGCAALHPLDEDLAELRsLAVHPDYRGRGIGRRLLEAL 77

                 ....*..
gi 612272081 119 ARWASER 125
Cdd:COG1246   78 LAEAREL 84
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
99-167 8.04e-04

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 36.94  E-value: 8.04e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 612272081  99 IWVKESLHGQGYGREIVQGIARWASERFQPPHFLYpVAEQNTASRRLVESLGGVLAGKRENIKYDAVVY 167
Cdd:COG0456   19 LAVDPEYRGRGIGRALLEAALERARERGARRLRLE-VREDNEAAIALYEKLGFEEVGERPNYYGDDALV 86
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
67-150 1.12e-03

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 36.28  E-value: 1.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612272081   67 EEVIFVARrrEDRQFVGVGGA--HNLRSPTPELGIWVKESLHGQGYGREIVQGIARWASERFQPPHFLypvaEQNTASRR 144
Cdd:pfam13508   2 GGRFFVAE--DDGKIVGFAALlpLDDEGALAELRLAVHPEYRGQGIGRALLEAAEAAAKEGGIKLLEL----ETTNRAAA 75

                  ....*.
gi 612272081  145 LVESLG 150
Cdd:pfam13508  76 FYEKLG 81
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
82-150 8.37e-03

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 35.03  E-value: 8.37e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612272081  82 VGVGGAHNLRSPTPELG-IWVKESLHGQGYGREIVQGIARWASERfQPPHFLYPVAEQNTASRRLVESLG 150
Cdd:COG0454   46 IGFAGLRRLDDKVLELKrLYVLPEYRGKGIGKALLEALLEWARER-GCTALELDTLDGNPAAIRFYERLG 114
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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