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Conserved domains on  [gi|586307207|gb|EWR10556|]
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competence protein ComGC [Staphylococcus aureus M1127]

Protein Classification

competence type IV pilus major pilin ComGC( domain architecture ID 11468256)

competence type IV pilus major pilin ComGC, also called comG operon protein ComGC, is required for transformation and DNA binding

Gene Ontology:  GO:0030420
PubMed:  32273343

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ComGC COG4537
Competence protein ComGC [Mobilome: prophages, transposons];
1-102 1.46e-27

Competence protein ComGC [Mobilome: prophages, transposons];


:

Pssm-ID: 443603 [Multi-domain]  Cd Length: 108  Bit Score: 96.53  E-value: 1.46e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586307207   1 MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI 80
Cdd:COG4537    4 KKRKLKKEKGFTLIEMLIVLLIISILLLIAVPNLTKQRETAQEKGCEANIKMVQSQVELYELDHGTYPASLEELVDEGYL 83

                         90       100
                 ....*....|....*....|...
gi 586307207  81 KEAQKTCKSGETITISN-GEAVA 102
Cdd:COG4537   84 KEKQPTCPNGGEYTIDSnGEVVA 106
 
Name Accession Description Interval E-value
ComGC COG4537
Competence protein ComGC [Mobilome: prophages, transposons];
1-102 1.46e-27

Competence protein ComGC [Mobilome: prophages, transposons];


Pssm-ID: 443603 [Multi-domain]  Cd Length: 108  Bit Score: 96.53  E-value: 1.46e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586307207   1 MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI 80
Cdd:COG4537    4 KKRKLKKEKGFTLIEMLIVLLIISILLLIAVPNLTKQRETAQEKGCEANIKMVQSQVELYELDHGTYPASLEELVDEGYL 83

                         90       100
                 ....*....|....*....|...
gi 586307207  81 KEAQKTCKSGETITISN-GEAVA 102
Cdd:COG4537   84 KEKQPTCPNGGEYTIDSnGEVVA 106
pilin_ComGC NF040999
competence type IV pilus major pilin ComGC; ComGC, encoded in the comG operon, is the major ...
 9-94 3.45e-19

competence type IV pilus major pilin ComGC; ComGC, encoded in the comG operon, is the major pilin of a type IV pilus involved in natural transformation of monoderm bacteria (those lacking an outer membrane) such as Bacillus subtilis and Streptococcus pneumoniae. In the seed alignment, Bacillus proteins have a pair of Cys residues likely to form a disulfide bond while Streptococcus proteins lack Cys residues.


Pssm-ID: 468929  Cd Length: 84  Bit Score: 74.86  E-value: 3.45e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586307207   9 QAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPsSIEDLIADGFIKeaQKTCK 88
Cdd:NF040999   2 KGFTLIEMLIVLLIISVLLLLFVPNLSKQKESVQEKGCEAVVKVVESQVELYELDHNKKP-SLSELVSEGYIT--KKQCP 78


                 ....*.
gi 586307207  89 SGETIT 94
Cdd:NF040999  79 NYKDYY 84
 
Name Accession Description Interval E-value
ComGC COG4537
Competence protein ComGC [Mobilome: prophages, transposons];
1-102 1.46e-27

Competence protein ComGC [Mobilome: prophages, transposons];


Pssm-ID: 443603 [Multi-domain]  Cd Length: 108  Bit Score: 96.53  E-value: 1.46e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586307207   1 MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI 80
Cdd:COG4537    4 KKRKLKKEKGFTLIEMLIVLLIISILLLIAVPNLTKQRETAQEKGCEANIKMVQSQVELYELDHGTYPASLEELVDEGYL 83

                         90       100
                 ....*....|....*....|...
gi 586307207  81 KEAQKTCKSGETITISN-GEAVA 102
Cdd:COG4537   84 KEKQPTCPNGGEYTIDSnGEVVA 106
pilin_ComGC NF040999
competence type IV pilus major pilin ComGC; ComGC, encoded in the comG operon, is the major ...
 9-94 3.45e-19

competence type IV pilus major pilin ComGC; ComGC, encoded in the comG operon, is the major pilin of a type IV pilus involved in natural transformation of monoderm bacteria (those lacking an outer membrane) such as Bacillus subtilis and Streptococcus pneumoniae. In the seed alignment, Bacillus proteins have a pair of Cys residues likely to form a disulfide bond while Streptococcus proteins lack Cys residues.


Pssm-ID: 468929  Cd Length: 84  Bit Score: 74.86  E-value: 3.45e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 586307207   9 QAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPsSIEDLIADGFIKeaQKTCK 88
Cdd:NF040999   2 KGFTLIEMLIVLLIISVLLLLFVPNLSKQKESVQEKGCEAVVKVVESQVELYELDHNKKP-SLSELVSEGYIT--KKQCP 78


                 ....*.
gi 586307207  89 SGETIT 94
Cdd:NF040999  79 NYKDYY 84
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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