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Conserved domains on  [gi|581788067|gb|EVR91272|]
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regulatory protein recX [Staphylococcus aureus M1470]

Protein Classification

regulatory protein RecX( domain architecture ID 10014591)

regulatory protein RecX modulates RecA activities (both recombinase and coprotease) through direct physical interaction

CATH:  1.10.10.10
Gene Ontology:  GO:0006282
PubMed:  18650935

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
recX PRK14135
recombination regulator RecX; Provisional
4-266 9.96e-106

recombination regulator RecX; Provisional


:

Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 307.52  E-value: 9.96e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067   4 ITKIEVQKKNKERFNLFLDEQFEMGIDIDTLVKFNLKKGQQLEAADMAEIQKYDHYRIGLNKAIQYLSYKKRTEKEVIQY 83
Cdd:PRK14135   1 ITKITVQKKNKERYNIFLDEKYAFSVDEDTLVKFMLKKGKELDEEDLEEIQYADQVSKGKNLALYYLSYQMRTEKEVRDY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067  84 LQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIRTTDKGPKIYQQKLYQLGIEPNIIEMFTELYREQQELDDIIQ 163
Cdd:PRK14135  81 LKKHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIEVAQK 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067 164 IAEKISKT-KKGPQNKVKEKVMQSLIQKGFEMETIHAVLNEMDFTQDEAVLDDLLQRDLEKIYNKNRkKYTQQKLISKTI 242
Cdd:PRK14135 161 LAEKLLKKyQKLPFKALKQKIIQSLLTKGFSYEVIKAALEELDLEQDEEEEQELLQKELEKAYRKYS-KYDGYELKQKLK 239
                        250       260
                 ....*....|....*....|....
gi 581788067 243 EGLMRKGYKYDKIKAKLEESGIAD 266
Cdd:PRK14135 240 QALYRKGFSYDDIDSFLREYGIED 263
 
Name Accession Description Interval E-value
recX PRK14135
recombination regulator RecX; Provisional
4-266 9.96e-106

recombination regulator RecX; Provisional


Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 307.52  E-value: 9.96e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067   4 ITKIEVQKKNKERFNLFLDEQFEMGIDIDTLVKFNLKKGQQLEAADMAEIQKYDHYRIGLNKAIQYLSYKKRTEKEVIQY 83
Cdd:PRK14135   1 ITKITVQKKNKERYNIFLDEKYAFSVDEDTLVKFMLKKGKELDEEDLEEIQYADQVSKGKNLALYYLSYQMRTEKEVRDY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067  84 LQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIRTTDKGPKIYQQKLYQLGIEPNIIEMFTELYREQQELDDIIQ 163
Cdd:PRK14135  81 LKKHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIEVAQK 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067 164 IAEKISKT-KKGPQNKVKEKVMQSLIQKGFEMETIHAVLNEMDFTQDEAVLDDLLQRDLEKIYNKNRkKYTQQKLISKTI 242
Cdd:PRK14135 161 LAEKLLKKyQKLPFKALKQKIIQSLLTKGFSYEVIKAALEELDLEQDEEEEQELLQKELEKAYRKYS-KYDGYELKQKLK 239
                        250       260
                 ....*....|....*....|....
gi 581788067 243 EGLMRKGYKYDKIKAKLEESGIAD 266
Cdd:PRK14135 240 QALYRKGFSYDDIDSFLREYGIED 263
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
55-205 9.60e-33

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 117.20  E-value: 9.60e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067  55 KYDHYRIGLNKAIQYLSYKKRTEKEVIQYLQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIRTTDKGPKIYQQK 134
Cdd:COG2137    1 KEDTEKKARNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRRKGYGPRRIRQE 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 581788067 135 LYQLGIEPNIIEMFTELYREQQELDDIIQIAEK-ISKTKKGPQNKVKEKVMQSLIQKGFEMETIHAVLNEMD 205
Cdd:COG2137   81 LRQKGIDEELIEEALEELDEEDELEAARELARKkFGSLKPLDPAKEKQKLARFLARRGFSSDLIRRVLRELL 152
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
84-203 6.57e-25

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 95.73  E-value: 6.57e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067   84 LQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIRTTDKGPKIYQQKLYQLGIEPNIIEMFTELYREQQELddIIQ 163
Cdd:pfam02631   1 LRKKGFSEEVIEEVLDRLKELGYLDDARFAESFVRSRARTRGKGPRRIRQELRQKGVDEEIIEEALEEFDEEEQI--ARE 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 581788067  164 IAEKISKTKKGPQN-KVKEKVMQSLIQKGFEMETIHAVLNE 203
Cdd:pfam02631  79 LAEKKFKRYPAESDrKLKQKLIRFLARRGFSSEVIRAALQE 119
 
Name Accession Description Interval E-value
recX PRK14135
recombination regulator RecX; Provisional
4-266 9.96e-106

recombination regulator RecX; Provisional


Pssm-ID: 237619 [Multi-domain]  Cd Length: 263  Bit Score: 307.52  E-value: 9.96e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067   4 ITKIEVQKKNKERFNLFLDEQFEMGIDIDTLVKFNLKKGQQLEAADMAEIQKYDHYRIGLNKAIQYLSYKKRTEKEVIQY 83
Cdd:PRK14135   1 ITKITVQKKNKERYNIFLDEKYAFSVDEDTLVKFMLKKGKELDEEDLEEIQYADQVSKGKNLALYYLSYQMRTEKEVRDY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067  84 LQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIRTTDKGPKIYQQKLYQLGIEPNIIEMFTELYREQQELDDIIQ 163
Cdd:PRK14135  81 LKKHEISEEIISEVIDKLKEEKYIDDKEYAESYVRTNINTGDKGPRVIKQKLLQKGIEDEIIEEALSEYTEEDQIEVAQK 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067 164 IAEKISKT-KKGPQNKVKEKVMQSLIQKGFEMETIHAVLNEMDFTQDEAVLDDLLQRDLEKIYNKNRkKYTQQKLISKTI 242
Cdd:PRK14135 161 LAEKLLKKyQKLPFKALKQKIIQSLLTKGFSYEVIKAALEELDLEQDEEEEQELLQKELEKAYRKYS-KYDGYELKQKLK 239
                        250       260
                 ....*....|....*....|....
gi 581788067 243 EGLMRKGYKYDKIKAKLEESGIAD 266
Cdd:PRK14135 240 QALYRKGFSYDDIDSFLREYGIED 263
RecX COG2137
SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, ...
55-205 9.60e-33

SOS response regulatory protein OraA/RecX, interacts with RecA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441740 [Multi-domain]  Cd Length: 154  Bit Score: 117.20  E-value: 9.60e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067  55 KYDHYRIGLNKAIQYLSYKKRTEKEVIQYLQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIRTTDKGPKIYQQK 134
Cdd:COG2137    1 KEDTEKKARNRALRLLARRERSRKELRRKLARKGFDEEEIEEVLDRLKEEGYLDDERFAESYVRSRLRRKGYGPRRIRQE 80
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 581788067 135 LYQLGIEPNIIEMFTELYREQQELDDIIQIAEK-ISKTKKGPQNKVKEKVMQSLIQKGFEMETIHAVLNEMD 205
Cdd:COG2137   81 LRQKGIDEELIEEALEELDEEDELEAARELARKkFGSLKPLDPAKEKQKLARFLARRGFSSDLIRRVLRELL 152
RecX pfam02631
RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found ...
84-203 6.57e-25

RecX family; RecX is a putative bacterial regulatory protein. The gene encoding RecX is found downstream of recA, and is thought to interact with the RecA protein.


Pssm-ID: 460631 [Multi-domain]  Cd Length: 123  Bit Score: 95.73  E-value: 6.57e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067   84 LQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIRTTDKGPKIYQQKLYQLGIEPNIIEMFTELYREQQELddIIQ 163
Cdd:pfam02631   1 LRKKGFSEEVIEEVLDRLKELGYLDDARFAESFVRSRARTRGKGPRRIRQELRQKGVDEEIIEEALEEFDEEEQI--ARE 78
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 581788067  164 IAEKISKTKKGPQN-KVKEKVMQSLIQKGFEMETIHAVLNE 203
Cdd:pfam02631  79 LAEKKFKRYPAESDrKLKQKLIRFLARRGFSSEVIRAALQE 119
recX PRK14134
recombination regulator RecX; Provisional
3-261 1.02e-20

recombination regulator RecX; Provisional


Pssm-ID: 184530 [Multi-domain]  Cd Length: 283  Bit Score: 89.09  E-value: 1.02e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067   3 KITKIEVQKKNKERFNLFLDEQFEMGIDIDTLVKFNLKKGQQLEAADMAEIQKYDHYRIGLNKAIQYLSYKKRTEKEVIQ 82
Cdd:PRK14134   4 IITKIEVQKRNKDRVNVYIDEEFAFACSAELVYYHNLKKGKVIDVNSLNDIIKEDNYIKCKGYALKYIEKSYKTEKQIKE 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067  83 YLQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIrtTDKGPKIYQQKLYQLGIEPNIIEMFTELYREQQELDDII 162
Cdd:PRK14134  84 KLYLKEYDEDAVNRVIRFLKEYNFIDDDKYCDMYIREKI--NSYGRNKIKYTLLNKGIKENIIIEKINNIDEEKEKKVAY 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067 163 QIAEK---ISKTKKGPQNKVKEKVMQSLIQKGFEMETIHAVLNEM----DFTQD---EAVLDDLLQRDLEKIYNKNRKKY 232
Cdd:PRK14134 162 KLAEKkykILILSEKNKFKIYKKLGPYLISRGYSSNIAEWILNELikneALYKDnnsQNIENNIKDENIEELHNLARKRY 241
                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 581788067 233 T--------QQKLISKTIEGLMRKGYKYDKIKAKLEE 261
Cdd:PRK14134 242 DiiikseddKNKIYRRLSNYLLRRGYSWEEVKKSLNE 278
recX PRK00117
recombination regulator RecX; Reviewed
63-203 3.70e-14

recombination regulator RecX; Reviewed


Pssm-ID: 234646 [Multi-domain]  Cd Length: 157  Bit Score: 68.37  E-value: 3.70e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581788067  63 LNKAIQYLSYKKRTEKEVIQYLQKEEISEQAISEVIEYCYREKLIDHQDYAESLKNTMIRTTdKGPKIYQQKLYQLGIEP 142
Cdd:PRK00117  14 RARALRLLARREHSRAELRRKLAAKGFSEEVIEAVLDRLKEEGLLDDERFAESFVRSRARKG-YGPRRIRQELRQKGVDR 92
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 581788067 143 NIIEMFTELYREQQElDDIIQIAEKISKTKKGPQNKVKEKVMQSLIQKGFEMETIHAVLNE 203
Cdd:PRK00117  93 EIIEEALAELDIDWE-ELARELARKKFRRPLPDDAKEKAKLVRFLARRGFSMDVIQRVLRN 152
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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