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Conserved domains on  [gi|581493607|gb|EVP02478|]
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single-stranded DNA-binding protein [Staphylococcus aureus M1094]

Protein Classification

single stranded DNA-binding domain-containing protein( domain architecture ID 489)

single stranded DNA-binding domain-containing protein may bind preferentially to single-stranded DNA

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RPA_2b-aaRSs_OBF_like super family cl09930
Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with ...
 1-156 2.44e-57

Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold.; This superfamily includes two oligonucleotide/oligosaccharide binding fold (OBF) domain families. One of these contains the OBF domains of the large (RPA1, 70kDa), middle (RPA2, RPA4, 32kDa) and small (RPA3, 14 kDa) subunits of human heterotrimeric Replication protein A (RPA), and similar domains. RPA is a nuclear single-strand (ss) DNA-binding protein involved in most aspects of DNA metabolism. This family includes the four OBF domains of RPA1 [DNA-binding domain (DBD)-A, DBD-B, DBD-C, and RPA1N], the OBF domain of RPA2 (RPA2 DBD-D), RPA3, and the OBF domain of RPA4. The major DNA binding activity of human RPA and Saccharomyces cerevisiae RPA appears to be associated with DBD-A and -B, of RPA1. RPA1 DBD-C shows only weak ssDNA-binding activity and is involved in trimerization. The other OBF domain family in this superfamily is the N-terminal, anticodon recognition domain of class 2b aminoacyl-tRNA synthetases (aaRSs). aaRSs catalyze the specific attachment of amino acids to their cognate tRNAs during protein biosynthesis. Class 2b aaRSs include the homodimeric aspartyl-, asparaginyl-, and lysyl-tRNA synthetases.


The actual alignment was detected with superfamily member PRK06751:

Pssm-ID: 471953 [Multi-domain]  Cd Length: 173  Bit Score: 176.91  E-value: 2.44e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   1 MLNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQGEREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQTR 80
Cdd:PRK06751   1 MMNRVILVGRLTKDPDLRYTPNGVAVATFTLAVNRAFANQQGEREADFINCVIWRKQAENVANYLKKGSLAGVDGRLQTR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607  81 NYENKEGQRVYVTEVVADSIQFLEPKNSNDTQQDLYQ---------QQVQQTRGQSQYSNNKPVK--------DNPFANA 143
Cdd:PRK06751  81 NYEGQDGKRVYVTEVLAESVQFLEPRNGGGEQRGSFNqqpsgagfgNQSSNPFGQSSNSGNQGNQgnsgftknDDPFSNV 160

                        170
                 ....*....|...
gi 581493607 144 NGPIELNDDDLPF 156
Cdd:PRK06751 161 GQPIDISDDDLPF 173
 
Name Accession Description Interval E-value
PRK06751 PRK06751
single-stranded DNA-binding protein; Provisional
 1-156 2.44e-57

single-stranded DNA-binding protein; Provisional


Pssm-ID: 168659 [Multi-domain]  Cd Length: 173  Bit Score: 176.91  E-value: 2.44e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   1 MLNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQGEREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQTR 80
Cdd:PRK06751   1 MMNRVILVGRLTKDPDLRYTPNGVAVATFTLAVNRAFANQQGEREADFINCVIWRKQAENVANYLKKGSLAGVDGRLQTR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607  81 NYENKEGQRVYVTEVVADSIQFLEPKNSNDTQQDLYQ---------QQVQQTRGQSQYSNNKPVK--------DNPFANA 143
Cdd:PRK06751  81 NYEGQDGKRVYVTEVLAESVQFLEPRNGGGEQRGSFNqqpsgagfgNQSSNPFGQSSNSGNQGNQgnsgftknDDPFSNV 160

                        170
                 ....*....|...
gi 581493607 144 NGPIELNDDDLPF 156
Cdd:PRK06751 161 GQPIDISDDDLPF 173
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
 1-156 1.96e-54

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 169.14  E-value: 1.96e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607    1 MLNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQGE--READFINIIVFKKQAENVNKYLSKGSLAGVDGRLQ 78
Cdd:TIGR00621   3 MVNKVILVGRLTRDPELRYTPSGNAVANFTLATNRRWKDQDGEwkEETEWHDIVIFGRLAEVAAQYLKKGSLVYVEGRLR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   79 TRNYENKEGQRVYVTEVVADSIQFLEPKNSNDTQQDLYQQQVQQTRGQSQYSNNKPVKDN----PFANANGPIELNDDDL 154
Cdd:TIGR00621  83 TRKWEDQNGQKRSKTEIIADNVQLLDLLGARAQGGEFSGGGGSGNRPQGGQEQSATGKDPaqsaPQSGSADPIDGDDDEI 162


                  ..
gi 581493607  155 PF 156
Cdd:TIGR00621 163 PF 164
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
2-110 1.68e-52

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 162.32  E-value: 1.68e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   2 LNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQGER--EADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQT 79
Cdd:COG0629    1 MNKVTLVGRLGKDPELRYTPSGTAVANFRLAVNRRYKDQDGEWkdETDWHRVVAWGKLAENAAEYLKKGDKVYVEGRLRT 80

                         90       100       110
                 ....*....|....*....|....*....|.
gi 581493607  80 RNYENKEGQRVYVTEVVADSIQFLEPKNSND 110
Cdd:COG0629   81 RSWEDKDGQKRYTTEVVADEIQFLGSRPSGG 111
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 2-103 1.90e-44

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 141.60  E-value: 1.90e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607    2 LNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTN-AQGEREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQTR 80
Cdd:pfam00436   1 MNKVILVGRLTRDPELRYTPNGNAVANFTLATNRRFKDrGEGDEETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQTR 80

                          90       100
                  ....*....|....*....|...
gi 581493607   81 NYENKEGQRVYVTEVVADSIQFL 103
Cdd:pfam00436  81 KYEDQEGQKRYVTEIVADEVQFL 103
SSB_OBF cd04496
SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs ...
 6-103 4.98e-41

SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.


Pssm-ID: 239942  Cd Length: 100  Bit Score: 132.74  E-value: 4.98e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   6 ILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNA-QGEREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQTRNYEN 84
Cdd:cd04496    2 ILIGRLGKDPELRYTPSGTPVARFSLAVNRRRKDRdEEEEETDWIRVVAFGKLAENAAKYLKKGDLVYVEGRLRTRSWED 81

                         90
                 ....*....|....*....
gi 581493607  85 KEGQRVYVTEVVADSIQFL 103
Cdd:cd04496   82 KDGQKRYGTEVVADRIEFL 100
 
Name Accession Description Interval E-value
PRK06751 PRK06751
single-stranded DNA-binding protein; Provisional
 1-156 2.44e-57

single-stranded DNA-binding protein; Provisional


Pssm-ID: 168659 [Multi-domain]  Cd Length: 173  Bit Score: 176.91  E-value: 2.44e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   1 MLNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQGEREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQTR 80
Cdd:PRK06751   1 MMNRVILVGRLTKDPDLRYTPNGVAVATFTLAVNRAFANQQGEREADFINCVIWRKQAENVANYLKKGSLAGVDGRLQTR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607  81 NYENKEGQRVYVTEVVADSIQFLEPKNSNDTQQDLYQ---------QQVQQTRGQSQYSNNKPVK--------DNPFANA 143
Cdd:PRK06751  81 NYEGQDGKRVYVTEVLAESVQFLEPRNGGGEQRGSFNqqpsgagfgNQSSNPFGQSSNSGNQGNQgnsgftknDDPFSNV 160

                        170
                 ....*....|...
gi 581493607 144 NGPIELNDDDLPF 156
Cdd:PRK06751 161 GQPIDISDDDLPF 173
PRK07275 PRK07275
single-stranded DNA-binding protein; Provisional
 1-156 3.91e-56

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180915 [Multi-domain]  Cd Length: 162  Bit Score: 173.15  E-value: 3.91e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   1 MLNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQGEREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQTR 80
Cdd:PRK07275   1 MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGEREADFINCVIWRQQAENLANWAKKGALIGVTGRIQTR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607  81 NYENKEGQRVYVTEVVADSIQFLEPKNSNDTQQ----DLYQQQVQQTRGQSQYSNNKP---VKDNPFANANgPIELNDDD 153
Cdd:PRK07275  81 NYENQQGQRVYVTEVVADNFQMLESRATREGGSggsyNGGFNNAPSANSYSAPAQQTPnfgRDESPFGNSN-PMDISDDD 159


                 ...
gi 581493607 154 LPF 156
Cdd:PRK07275 160 LPF 162
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
 1-156 1.96e-54

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 169.14  E-value: 1.96e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607    1 MLNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQGE--READFINIIVFKKQAENVNKYLSKGSLAGVDGRLQ 78
Cdd:TIGR00621   3 MVNKVILVGRLTRDPELRYTPSGNAVANFTLATNRRWKDQDGEwkEETEWHDIVIFGRLAEVAAQYLKKGSLVYVEGRLR 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   79 TRNYENKEGQRVYVTEVVADSIQFLEPKNSNDTQQDLYQQQVQQTRGQSQYSNNKPVKDN----PFANANGPIELNDDDL 154
Cdd:TIGR00621  83 TRKWEDQNGQKRSKTEIIADNVQLLDLLGARAQGGEFSGGGGSGNRPQGGQEQSATGKDPaqsaPQSGSADPIDGDDDEI 162


                  ..
gi 581493607  155 PF 156
Cdd:TIGR00621 163 PF 164
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
2-110 1.68e-52

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 162.32  E-value: 1.68e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   2 LNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQGER--EADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQT 79
Cdd:COG0629    1 MNKVTLVGRLGKDPELRYTPSGTAVANFRLAVNRRYKDQDGEWkdETDWHRVVAWGKLAENAAEYLKKGDKVYVEGRLRT 80

                         90       100       110
                 ....*....|....*....|....*....|.
gi 581493607  80 RNYENKEGQRVYVTEVVADSIQFLEPKNSND 110
Cdd:COG0629   81 RSWEDKDGQKRYTTEVVADEIQFLGSRPSGG 111
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 2-103 1.90e-44

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 141.60  E-value: 1.90e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607    2 LNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTN-AQGEREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQTR 80
Cdd:pfam00436   1 MNKVILVGRLTRDPELRYTPNGNAVANFTLATNRRFKDrGEGDEETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQTR 80

                          90       100
                  ....*....|....*....|...
gi 581493607   81 NYENKEGQRVYVTEVVADSIQFL 103
Cdd:pfam00436  81 KYEDQEGQKRYVTEIVADEVQFL 103
PRK06752 PRK06752
single-stranded DNA-binding protein; Validated
 1-106 4.13e-43

single-stranded DNA-binding protein; Validated


Pssm-ID: 168660  Cd Length: 112  Bit Score: 138.63  E-value: 4.13e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   1 MLNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQGEREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQTR 80
Cdd:PRK06752   1 MMNRVVLIGRLTKEPELYYTKQGVAYARVCVAVNRGFRNSLGEQQVDFINCVVWRKSAENVTEYCTKGSLVGITGRIHTR 80

                         90       100
                 ....*....|....*....|....*.
gi 581493607  81 NYENKEGQRVYVTEVVADSIQFLEPK 106
Cdd:PRK06752  81 NYEDDQGKRIYITEVVIESITFLERR 106
SSB_OBF cd04496
SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs ...
 6-103 4.98e-41

SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.


Pssm-ID: 239942  Cd Length: 100  Bit Score: 132.74  E-value: 4.98e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   6 ILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNA-QGEREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQTRNYEN 84
Cdd:cd04496    2 ILIGRLGKDPELRYTPSGTPVARFSLAVNRRRKDRdEEEEETDWIRVVAFGKLAENAAKYLKKGDLVYVEGRLRTRSWED 81

                         90
                 ....*....|....*....
gi 581493607  85 KEGQRVYVTEVVADSIQFL 103
Cdd:cd04496   82 KDGQKRYGTEVVADRIEFL 100
PRK07274 PRK07274
single-stranded DNA-binding protein; Provisional
 1-104 6.92e-38

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180914  Cd Length: 131  Bit Score: 126.03  E-value: 6.92e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   1 MLNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQGEREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQTR 80
Cdd:PRK07274   1 MYNKVILIGRLTATPELVKTANDKSVARVTLAVNRRFKNQNGEREADFINVVLWGKLAETLASYASKGSLISIDGELRTR 80

                         90       100
                 ....*....|....*....|....
gi 581493607  81 NYEnKEGQRVYVTEVVADSIQFLE 104
Cdd:PRK07274  81 KYE-KDGQTHYVTEVLCQSFQLLE 103
PRK08486 PRK08486
single-stranded DNA-binding protein; Provisional
 1-156 1.07e-27

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236275 [Multi-domain]  Cd Length: 182  Bit Score: 101.46  E-value: 1.07e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   1 MLNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQGER--EADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQ 78
Cdd:PRK08486   1 MFNKVILVGNLTRDVELRYLPSGSAIATIGLATSRRFKKQDGEKgeEVCFIDIRLFGRTAEIANQYLSKGSKVLIEGRLT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607  79 TRNYENKEGQRVYVTEVVADSIQFLEPKNSN---DTQQDLYQQQVQQTRGQSQY-------------SNNKPVKDNPFAN 142
Cdd:PRK08486  81 FESWMDQNGQKRSKHTITAESMQMLDSKSDNpqaNAMQDNSFHENFNNNYPGNYnnpsqdpymnqaqSYNQNAYAKENQQ 160

                        170       180
                 ....*....|....*....|..
gi 581493607 143 ANGP--------IELNDDDLPF 156
Cdd:PRK08486 161 AQPPkyensvpeIDIDEEEIPF 182
PRK06863 PRK06863
single-stranded DNA-binding protein; Provisional
 2-156 1.06e-24

single-stranded DNA-binding protein; Provisional


Pssm-ID: 136097 [Multi-domain]  Cd Length: 168  Bit Score: 93.49  E-value: 1.06e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   2 LNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQ-GERE--ADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQ 78
Cdd:PRK06863   4 INKVIIVGHLGNDPEIRTMPNGEAVANISVATSESWTDKNtGERRevTEWHRIVFYRRQAEVAGEYLRKGSQVYVEGRLK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607  79 TRNYENKEGQRVYVTEVVADSIQFLEPKN-------SNDTQQDLYQQQVQQTRGQSQYSNNKPVKDNPFANANGPIELND 151
Cdd:PRK06863  84 TRKWQDQNGQDRYTTEIQGDVLQMLGGRNqrnaggyGNSGPAPQQSYQAGQTNNGNSQQASRPAPQQAAPQAEPPMDGFD 163


                 ....*
gi 581493607 152 DDLPF 156
Cdd:PRK06863 164 DDIPF 168
PRK07772 PRK07772
single-stranded DNA-binding protein; Provisional
 1-100 9.94e-24

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236092 [Multi-domain]  Cd Length: 186  Bit Score: 91.25  E-value: 9.94e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   1 MLNRTI-LVGRLTRDPELRTTQSGVNVASFTLAVN-RTFTNAQGE---READFINIIVFKKQAENVNKYLSKGSLAGVDG 75
Cdd:PRK07772   2 AGDTTItVVGNLTADPELRFTPSGAAVANFTVASTpRTFDRQTNEwkdGEALFLRCSIWRQAAENVAESLTKGMRVIVTG 81

                         90       100
                 ....*....|....*....|....*
gi 581493607  76 RLQTRNYENKEGQRVYVTEVVADSI 100
Cdd:PRK07772  82 RLKQRSYETREGEKRTVVELEVDEI 106
PRK06958 PRK06958
single-stranded DNA-binding protein; Provisional
 2-103 1.04e-20

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180777 [Multi-domain]  Cd Length: 182  Bit Score: 83.31  E-value: 1.04e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   2 LNRTILVGRLTRDPELRTTQSGVNVASFTLAV-NRTFTNAQGE-REA-DFINIIVFKKQAENVNKYLSKGSLAGVDGRLQ 78
Cdd:PRK06958   4 VNKVILVGNLGADPEVRYLPSGDAVANIRLATtDRYKDKASGEfKEAtEWHRVAFFGRLAEIVGEYLKKGSSVYIEGRIR 83

                         90       100
                 ....*....|....*....|....*
gi 581493607  79 TRNYENKEGQRVYVTEVVADSIQFL 103
Cdd:PRK06958  84 TRKWQGQDGQDRYSTEIVADQMQML 108
PRK09010 PRK09010
single-stranded DNA-binding protein; Provisional
 2-156 2.06e-20

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236362 [Multi-domain]  Cd Length: 177  Bit Score: 82.59  E-value: 2.06e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   2 LNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQ-GE-RE-ADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQ 78
Cdd:PRK09010   6 VNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKQtGEmKEqTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQLR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607  79 TRNYENKEGQRVYVTEVVAD---SIQFLEPKNSNDTQQDLYQQQVQQT--------RGQSQYS---NNKPVKDNPFANAN 144
Cdd:PRK09010  86 TRKWTDQSGQDRYTTEVVVNvggTMQMLGGRQGGGAPAGGNIGGQQQGgwgqpqqpQGGNQFSggaQSRPQQSAPAAPSN 165

                        170
                 ....*....|..
gi 581493607 145 GPIELNDDDLPF 156
Cdd:PRK09010 166 EPPMDFDDDIPF 177
PRK05733 PRK05733
single-stranded DNA-binding protein; Provisional
 2-156 2.75e-20

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235585 [Multi-domain]  Cd Length: 172  Bit Score: 81.90  E-value: 2.75e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   2 LNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQ-GER--EADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQ 78
Cdd:PRK05733   5 VNKVILVGTCGQDPEVRYLPNGNAVTNLSLATSEQWTDKQsGQKveRTEWHRVSLFGKVAEIAGEYLRKGSQVYIEGKLQ 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607  79 TRNYEnKEGQRVYVTEVVAD---SIQFL--EPKNSNDTQQDLYQQQVQQTR------GQSQYSNNKPVKDNPFANANGPI 147
Cdd:PRK05733  85 TREWE-KDGIKRYTTEIVVDmqgTMQLLggRPQGDDQGGQGGGNYNQSAPRqqaqrpQQAAQQQSRPAPQQPAPQPAADF 163


                 ....*....
gi 581493607 148 ELNDDDLPF 156
Cdd:PRK05733 164 DSFDDDIPF 172
PRK06642 PRK06642
single-stranded DNA-binding protein; Provisional
 2-156 9.61e-19

single-stranded DNA-binding protein; Provisional


Pssm-ID: 135984  Cd Length: 152  Bit Score: 77.45  E-value: 9.61e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   2 LNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTN-AQGERE--ADFINIIVFKKQ-AENVNKYLSKGSLAGVDGRL 77
Cdd:PRK06642   5 LNKVILIGNVGRDPEIRTTGEGKKIINLSLATTETWKDrITSERKerTEWHRVVIFSEGlVSVVERYVTKGSKLYIEGSL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607  78 QTRNYENKEGQRVYVTEVVADSIQ----FLEPKNSNDTQQDLyqqqvqqtrGQSQYSNNKPvKDNPFANANgpielNDDD 153
Cdd:PRK06642  85 QTRKWNDNSGQEKYTTEVVLQNFNsqliLLDSKNSNNHNQDS---------GHSEYKHPET-KNHSFDHSD-----LDDE 149


                 ...
gi 581493607 154 LPF 156
Cdd:PRK06642 150 IPF 152
PRK08763 PRK08763
single-stranded DNA-binding protein; Provisional
 2-156 9.98e-18

single-stranded DNA-binding protein; Provisional


Pssm-ID: 181549 [Multi-domain]  Cd Length: 164  Bit Score: 75.36  E-value: 9.98e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   2 LNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQG--EREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQT 79
Cdd:PRK08763   5 INKVILVGNLGNDPDIKYTQSGMTITRISLATTSVRKDREGntQERTEWHRVKFFGKLGEIAGEYLRKGSQCYIEGSIRY 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607  80 RNYENKEGQRVYVTEVVADSIQFLEPKNSNDTQQDLYQQQVQQT-RGQSQYSNNKPVKDNPFANANGPI--ELNDDDLPF 156
Cdd:PRK08763  85 DKFTGQDGQERYVTEIVADEMQMLGGRGEGGGGGGGGIRPQRQPaPRQNNGQDYAPRRQQPAPQQSAPPmdDFADDDIPF 164
PRK13732 PRK13732
single-stranded DNA-binding protein; Provisional
 2-96 4.37e-16

single-stranded DNA-binding protein; Provisional


Pssm-ID: 184284 [Multi-domain]  Cd Length: 175  Bit Score: 71.30  E-value: 4.37e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   2 LNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQ-GE--READFINIIVFKKQAENVNKYLSKGSLAGVDGRLQ 78
Cdd:PRK13732   6 INKVILVGRLGKDPEVRYIPNGGAVANLQVATSESWRDKQtGEmrEQTEWHRVVLFGKLAEVAGEYLRKGAQVYIEGQLR 85

                         90
                 ....*....|....*...
gi 581493607  79 TRNYENKeGQRVYVTEVV 96
Cdd:PRK13732  86 TRSWEDN-GITRYVTEIL 102
PRK06341 PRK06341
single-stranded DNA-binding protein; Provisional
 2-156 7.15e-15

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235782 [Multi-domain]  Cd Length: 166  Bit Score: 67.91  E-value: 7.15e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   2 LNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTN-AQGER--EADFINIIVFK----KQAEnvnKYLSKGSLAGVD 74
Cdd:PRK06341   5 VNKVILIGNLGADPEIRRTQDGRPIANLRIATSETWRDrNSGERkeKTEWHRVVIFNeglcKVAE---QYLKKGAKVYIE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607  75 GRLQTRNYENKEGQRVYVTEVV----ADSIQFLEPKNSNDTQQDLYQQQVQQTRGQSQYSNNKPVKDNPFANANGPIELn 150
Cdd:PRK06341  82 GQLQTRKWTDQSGVERYSTEVVlqgfNSTLTMLDGRGEGGGGGGGGDDGGGGDFGSSGPSRGGPRPASSGGGGNFSRDM- 160


                 ....*.
gi 581493607 151 DDDLPF 156
Cdd:PRK06341 161 DDDIPF 166
PRK07459 PRK07459
single-stranded DNA-binding protein; Provisional
 2-77 6.28e-14

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180986  Cd Length: 121  Bit Score: 64.32  E-value: 6.28e-14
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 581493607   2 LNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNaqgeREADFINIIVFKKQAENVNKYLSKGSLAGVDGRL 77
Cdd:PRK07459   3 LNSVTLVGRAGRDPEVRYFESGSVVCNLTLAVNRRSRD----DEPDWFNLEIWGKTAQVAADYVKKGSLIGITGSL 74
PRK06293 PRK06293
single-stranded DNA-binding protein; Provisional
 7-156 6.64e-12

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180517 [Multi-domain]  Cd Length: 161  Bit Score: 59.92  E-value: 6.64e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   7 LVGRLTRDPELRTTQSGVNVASFTLAVNrtfTNAQGEREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQTRNYENKE 86
Cdd:PRK06293   6 IVGRLGADPEERMTSKGKRVVVLRLGVK---SRVGSKDETVWCRCNIWGNRYDKMLPYLKKGSGVIVAGEMSPESYVDKD 82

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 581493607  87 GQRVYVTEVVADSIQFLEPKNSNDTQQDLYQQQVQQTRGQSQYSNNKP---------VKDNPFANANGPIELNDDDLPF 156
Cdd:PRK06293  83 GSPQSSLVVSVDTIKFSPFGRNEGSRQPSAGEDEGQQRGYDNVSIGFEgesldtesaLDKDMYAGYGQDQQYASEDVPF 161
DnaE COG0587
DNA polymerase III, alpha subunit [Replication, recombination and repair];
18-101 5.58e-04

DNA polymerase III, alpha subunit [Replication, recombination and repair];


Pssm-ID: 440352 [Multi-domain]  Cd Length: 1050  Bit Score: 39.28  E-value: 5.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581493607   18 RTTQSGVNVASFTLavnrtftnaqgEREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQTRNyenkegqrvYVTEVVA 97
Cdd:COG0587   986 PGTKKGKRMAFVTL-----------EDETGSIEVVVFPEVYERYRRLLLEDRLLLVRGKVQRRD---------GVVHLIA 1045


                  ....
gi 581493607   98 DSIQ 101
Cdd:COG0587  1046 ERIE 1049
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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