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Conserved domains on  [gi|581229976|gb|EVM44000|]
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Na(+)/H(+) antiporter subunit C1 [Staphylococcus aureus M0916]

Protein Classification

Na(+)/H(+) antiporter subunit C( domain architecture ID 10013098)

Na(+)/H(+) antiporter subunit C (MrpC) is part of a heterooligomeric complex together with MrpA, MrpB, MrpD, MrpE, MrpF and MrpG, which is involved in resistance to Na(+) and excretion of Li(+) and Na(+)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK08600 PRK08600
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-113 2.23e-62

putative monovalent cation/H+ antiporter subunit C; Reviewed


:

Pssm-ID: 181497  Cd Length: 113  Bit Score: 185.55  E-value: 2.23e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976   1 MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIA 80
Cdd:PRK08600   1 MEILMIIVIGILTAIAVYLILSKSLLRIIIGTTLLSHGANLLLLTMGGLKKGAVPILGEGVTSYVDPLPQALILTAIVIS 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 581229976  81 FATTAFFLVLAFRTYKELGTDNVESMKGVPEDD 113
Cdd:PRK08600  81 FGVTAFFLVLAYRTYKELGTDNVEQMRGVPEDD 113
 
Name Accession Description Interval E-value
PRK08600 PRK08600
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-113 2.23e-62

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 181497  Cd Length: 113  Bit Score: 185.55  E-value: 2.23e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976   1 MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIA 80
Cdd:PRK08600   1 MEILMIIVIGILTAIAVYLILSKSLLRIIIGTTLLSHGANLLLLTMGGLKKGAVPILGEGVTSYVDPLPQALILTAIVIS 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 581229976  81 FATTAFFLVLAFRTYKELGTDNVESMKGVPEDD 113
Cdd:PRK08600  81 FGVTAFFLVLAYRTYKELGTDNVEQMRGVPEDD 113
2a6301s03 TIGR00941
Multicomponent Na+:H+ antiporter, MnhC subunit; [Transport and binding proteins, Cations and ...
 1-104 1.13e-45

Multicomponent Na+:H+ antiporter, MnhC subunit; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273354  Cd Length: 104  Bit Score: 143.02  E-value: 1.13e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976    1 MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIA 80
Cdd:TIGR00941   1 MESIFALIIGILTASGVYLLLSRSVVRVVLGLALLGYAVNLFILTMGGLENKAPPILTLPVGPYVDPLPQALILTAIVIG 80

                          90       100
                  ....*....|....*....|....
gi 581229976   81 FATTAFFLVLAFRTYKELGTDNVE 104
Cdd:TIGR00941  81 FATTALFLVVALRAYQVAGTDDVE 104
MnhC COG1006
Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];
1-108 5.36e-43

Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];


Pssm-ID: 440630  Cd Length: 113  Bit Score: 136.40  E-value: 5.36e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976   1 MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIY--EANVKSYVDPIPQALILTAIV 78
Cdd:COG1006    1 MELLLALVIGVLFAIGVYLLLRRNLIKVIIGLSLLSNAVNLLLFAMGGLTGGAPPILgeGPPAAPYADPLPQALVLTAIV 80

                         90       100       110
                 ....*....|....*....|....*....|
gi 581229976  79 IAFATTAFFLVLAFRTYKELGTDNVESMKG 108
Cdd:COG1006   81 IGFAVTAFLLALAYRIYQLYGTDDVDELRE 110
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
4-106 2.79e-19

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 75.68  E-value: 2.79e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976    4 IMIFVSGILTAISVYLVL-SKSLIRIVMGTTLLTHAANLFLITMGGLKHgtvpiyeanvksyvDPIPQALILTAIVIAFA 82
Cdd:pfam00420   1 AYLLLSGLLFLIGLYGLLlRRNLLRVLLSLELMLNAVNLALVLFGRLTA--------------DPLPQALILTAIVIAAA 66

                          90       100
                  ....*....|....*....|....
gi 581229976   83 TTAFFLVLAFRTYKELGTDNVESM 106
Cdd:pfam00420  67 EAAVGLALLVRIYRTHGTDDVDSL 90
 
Name Accession Description Interval E-value
PRK08600 PRK08600
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-113 2.23e-62

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 181497  Cd Length: 113  Bit Score: 185.55  E-value: 2.23e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976   1 MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIA 80
Cdd:PRK08600   1 MEILMIIVIGILTAIAVYLILSKSLLRIIIGTTLLSHGANLLLLTMGGLKKGAVPILGEGVTSYVDPLPQALILTAIVIS 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 581229976  81 FATTAFFLVLAFRTYKELGTDNVESMKGVPEDD 113
Cdd:PRK08600  81 FGVTAFFLVLAYRTYKELGTDNVEQMRGVPEDD 113
2a6301s03 TIGR00941
Multicomponent Na+:H+ antiporter, MnhC subunit; [Transport and binding proteins, Cations and ...
 1-104 1.13e-45

Multicomponent Na+:H+ antiporter, MnhC subunit; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273354  Cd Length: 104  Bit Score: 143.02  E-value: 1.13e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976    1 MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIA 80
Cdd:TIGR00941   1 MESIFALIIGILTASGVYLLLSRSVVRVVLGLALLGYAVNLFILTMGGLENKAPPILTLPVGPYVDPLPQALILTAIVIG 80

                          90       100
                  ....*....|....*....|....
gi 581229976   81 FATTAFFLVLAFRTYKELGTDNVE 104
Cdd:TIGR00941  81 FATTALFLVVALRAYQVAGTDDVE 104
MnhC COG1006
Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];
1-108 5.36e-43

Multisubunit Na+/H+ antiporter, MnhC subunit [Inorganic ion transport and metabolism];


Pssm-ID: 440630  Cd Length: 113  Bit Score: 136.40  E-value: 5.36e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976   1 MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIY--EANVKSYVDPIPQALILTAIV 78
Cdd:COG1006    1 MELLLALVIGVLFAIGVYLLLRRNLIKVIIGLSLLSNAVNLLLFAMGGLTGGAPPILgeGPPAAPYADPLPQALVLTAIV 80

                         90       100       110
                 ....*....|....*....|....*....|
gi 581229976  79 IAFATTAFFLVLAFRTYKELGTDNVESMKG 108
Cdd:COG1006   81 IGFAVTAFLLALAYRIYQLYGTDDVDELRE 110
PRK12660 PRK12660
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-112 4.58e-34

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 183660  Cd Length: 114  Bit Score: 113.68  E-value: 4.58e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976   1 MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGL-KHGTVPIYEANVKSYVDPIPQALILTAIVI 79
Cdd:PRK12660   1 MNLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIMSMGGYgSSRSEPLITGGNQLFVDPLLQAIVLTAIVI 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 581229976  80 AFATTAFFLVLAFRTYKELGTDNVESMKGVPED 112
Cdd:PRK12660  81 GFGMTAFLLVLVYRTYKVTKEDEIEGLRGEDDA 113
PRK09094 PRK09094
putative monovalent cation/H+ antiporter subunit C; Reviewed
 1-103 1.91e-32

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236377  Cd Length: 114  Bit Score: 109.58  E-value: 1.91e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976   1 MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYE----ANVKSYVDPIPQALILTA 76
Cdd:PRK09094   1 MELVLALAIGVLTASGVWLLLRPRTFQVILGLSLLSYAVNLFIFAMGRLRVGAPPVLQpgvpVDLANYTDPLPQALVLTA 80

                         90       100
                 ....*....|....*....|....*..
gi 581229976  77 IVIAFATTAFFLVLAFRTYKELGTDNV 103
Cdd:PRK09094  81 IVIGFAMTALFLVVALASRGLTGTDHV 107
PRK12658 PRK12658
Na+/H+ antiporter subunit C;
1-107 4.97e-32

Na+/H+ antiporter subunit C;


Pssm-ID: 183658  Cd Length: 125  Bit Score: 109.00  E-value: 4.97e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976   1 MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKS----YVDPIPQALILTA 76
Cdd:PRK12658   1 MEALFAILVGVFFAAAIYLMLSRHIIRILFGLALLGNAVNLLIFTAGRLTREVPPLIPAGADVlaegAANPLPQALILTA 80

                         90       100       110
                 ....*....|....*....|....*....|.
gi 581229976  77 IVIAFATTAFFLVLAFRTYKELGTDNVESMK 107
Cdd:PRK12658  81 IVIGFGLLAFLLVLAYRAYQDLGTDDTDEMR 111
PRK12659 PRK12659
Na+/H+ antiporter subunit C;
1-107 1.13e-27

Na+/H+ antiporter subunit C;


Pssm-ID: 183659  Cd Length: 117  Bit Score: 97.81  E-value: 1.13e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976   1 MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIY----EANVKSYVDPIPQALILTA 76
Cdd:PRK12659   1 MEFLLAIVVGGLYAAGIYMMLRRSIVKLVIGLILLGNAANLLIFTVGRLTRGAPPLVpegaTAPAGPVADPLPQALILTA 80

                         90       100       110
                 ....*....|....*....|....*....|.
gi 581229976  77 IVIAFATTAFFLVLAFRTYKELGTDNVESMK 107
Cdd:PRK12659  81 IVIGFGVQAFAIVLIKRAYQVVGTDDLDEMK 111
PRK07946 PRK07946
putative monovalent cation/H+ antiporter subunit C; Reviewed
 3-104 3.09e-26

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236136  Cd Length: 163  Bit Score: 95.50  E-value: 3.09e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976   3 IIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGlKHGTVPI---YEANVKSYVDPIPQALILTAIVI 79
Cdd:PRK07946   5 LGLLVAIGVLTSAGVYLLLERSLTRMLLGLLLIGNGVNLLILTAGG-PAGNPPIlgrTSEYGETMADPLAQAMILTAIVI 83

                         90       100
                 ....*....|....*....|....*
gi 581229976  80 AFATTAFFLVLAFRTYKELGTDNVE 104
Cdd:PRK07946  84 TMGITAFVLALAYRSYRLTTADEVE 108
PRK07375 PRK07375
Na+/H+ antiporter subunit C;
1-100 1.86e-21

Na+/H+ antiporter subunit C;


Pssm-ID: 236004  Cd Length: 112  Bit Score: 81.85  E-value: 1.86e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976   1 MEIIMIFVSGILTAIS-VYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIY-EANVKSYVDPIPQALILTAIV 78
Cdd:PRK07375   1 MQLMIYALAIALLVIGlYGLIFKRNLLKKIIGLDVFQTGVNLFYIAIGYRSGGGVPILsPSGFTTYADPLPQALVLTAIV 80

                         90       100
                 ....*....|....*....|..
gi 581229976  79 IAFATTAFFLVLAFRTYKELGT 100
Cdd:PRK07375  81 IGFATTAVMLALIVKLYKDYGT 102
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
4-106 2.79e-19

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 75.68  E-value: 2.79e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976    4 IMIFVSGILTAISVYLVL-SKSLIRIVMGTTLLTHAANLFLITMGGLKHgtvpiyeanvksyvDPIPQALILTAIVIAFA 82
Cdd:pfam00420   1 AYLLLSGLLFLIGLYGLLlRRNLLRVLLSLELMLNAVNLALVLFGRLTA--------------DPLPQALILTAIVIAAA 66

                          90       100
                  ....*....|....*....|....
gi 581229976   83 TTAFFLVLAFRTYKELGTDNVESM 106
Cdd:pfam00420  67 EAAVGLALLVRIYRTHGTDDVDSL 90
PRK12661 PRK12661
putative monovalent cation/H+ antiporter subunit C; Reviewed
 11-107 3.46e-15

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 237162  Cd Length: 140  Bit Score: 66.33  E-value: 3.46e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976  11 ILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKS--------------------------- 63
Cdd:PRK12661  12 LLFGIGTFLILRRDMIKVIIGLSIISHAVNLLIVSSGVFEGTKVPIITEQGHEgsgsgiiyndnltsgilapivtngpet 91

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 581229976  64 -YVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMK 107
Cdd:PRK12661  92 eFVDPLVQALVLTAIVIGLATTAFILILAYRIYEEYGTTDIRELR 136
PRK08389 PRK08389
putative monovalent cation/H+ antiporter subunit C; Reviewed
 6-109 4.66e-14

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236258  Cd Length: 114  Bit Score: 62.83  E-value: 4.66e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976   6 IFVSGILTAISVYLVLSKS-LIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKS--YVDPIPQALILTAIVIAFA 82
Cdd:PRK08389   6 YFGAIALVLIGLYGVLVKKnLLKIIIGLDIMETGVNLLLISIGYVSGRSAPILSEGITPsnYVDPIPQALVLTAIVIGVS 85

                         90       100
                 ....*....|....*....|....*..
gi 581229976  83 TTAFFLVLAFRTYKELGTDNVESMKGV 109
Cdd:PRK08389  86 TTALALSVAIKLYEKYGTLNVEEIRRL 112
PRK08388 PRK08388
putative monovalent cation/H+ antiporter subunit C; Reviewed
 11-107 4.09e-07

putative monovalent cation/H+ antiporter subunit C; Reviewed


Pssm-ID: 236257  Cd Length: 119  Bit Score: 44.89  E-value: 4.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976  11 ILTAISVYLVLSK-SLIRIVMGTTLLTHAANLFLITMG-GLKHGTVPI------YEANVKSYVDPIPQALILTAIVIAFA 82
Cdd:PRK08388  11 LMIALGIYAFLYKrNLIKLILALDLIDSGIHLLLISLGyRMENGLPPTapiytgYETLKSPMVGPIPQALVLTSIVIGVC 90

                         90       100
                 ....*....|....*....|....*
gi 581229976  83 TTAFFLVLAFRTYKELGTDNVESMK 107
Cdd:PRK08388  91 VLSLAMALTINAYRHYGTLDVTKLR 115
PRK05715 PRK05715
NADH-quinone oxidoreductase subunit NuoK;
6-108 9.45e-03

NADH-quinone oxidoreductase subunit NuoK;


Pssm-ID: 180218  Cd Length: 100  Bit Score: 32.84  E-value: 9.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 581229976   6 IFVSGILTAISVY-LVLSKSLIRIVMGTTLLTHAANLFLITMGglkhgtvpiyeanvKSYVDPIPQALILTAIVIAFATT 84
Cdd:PRK05715   8 LILAAILFCIGLVgLLLRRNAIVVLMSIELMLNAVNLNFVAFS--------------SYLGDLDGQVFAFFVITVAAAEA 73

                         90       100
                 ....*....|....*....|....*..
gi 581229976  85 AF---FLVLAFRTYKELGTDNVESMKG 108
Cdd:PRK05715  74 AIglaILLQLYRNRGTIDVDDLNELKG 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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