|
Name |
Accession |
Description |
Interval |
E-value |
| PRK02463 |
PRK02463 |
OxaA-like protein precursor; Provisional |
1-243 |
5.82e-58 |
|
OxaA-like protein precursor; Provisional
Pssm-ID: 235040 Cd Length: 307 Bit Score: 188.02 E-value: 5.82e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 1 MKKK----ALLPLFLGIMVFLAGC-DYSKPEKRSGFFYNTFVDPMKNVLDWLGNNLlNDNYGLAIIILVLVIRIILLPFM 75
Cdd:PRK02463 1 MKKTlkriLFSGLALSMLLTLTGCvGRDKHGNPTGFIWNFLGAPMSYFIDYFANNL-GLGFGLAIIIVTIIVRLIILPLG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 76 LSNYKNSHMMRQKMKVAKPEVEKIQEKVKRARTQEEKMAANQELMQVYKKYDMNPIKSMlGCLPMLIQLPIIMGLYFVLk 155
Cdd:PRK02463 80 LYQSWKATYQSEKMAYLKPVFEPINERLKNATTQEEKMAAQTELMAAQRENGISMLGGI-GCLPLLIQMPFFSALYFAA- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 156 dQLVDGLFKyPHFLWFDLGRPDIWITIIAGVLYFIQAYVSSKTMPDEQRQMGYMMMVISPIMIIWISLSSASALGLYWSV 235
Cdd:PRK02463 158 -QYTKGVST-STFLGIDLGSPSLVLTAIIGVLYFFQSWLSMMGVPEEQREQMKAMMYMMPIMMVVFSFSSPAGVGLYWLV 235
|
....*...
gi 578583608 236 SAAFLVVQ 243
Cdd:PRK02463 236 GGFFSIIQ 243
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
73-246 |
3.62e-48 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 158.41 E-value: 3.62e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 73 PFMLSNYKNShmmrQKMKVAKPEVEKIQEKVKrartqEEKMAANQELMQVYKKYDMNPiksMLGCLPMLIQLPIIMGLYF 152
Cdd:TIGR03592 19 PLTLKQYKSM----RKMQELQPKLKEIQEKYK-----EDPQKLQQEMMKLYKEEGVNP---LGGCLPLLIQMPIFIALYQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 153 VLkdqLVDGLFKYPHFLW-FDLGRPDIW--ITIIAGVLYFIQAYVSSKTMPDEQRQmgYMMMVISPIMIIWISLSSASAL 229
Cdd:TIGR03592 87 VL---LRSIELRHAPFLWiIDLSSPDPYyiLPILMGVTMFLQQKLSPKGPPDPAQQ--KMMMYFMPLMFLFFFLSFPAGL 161
|
170
....*....|....*..
gi 578583608 230 GLYWSVSAAFLVVQTHF 246
Cdd:TIGR03592 162 VLYWVVSNLFTIIQQLI 178
|
|
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
30-253 |
7.35e-47 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 156.05 E-value: 7.35e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 30 GFFYnTFVDPMKNVLDWLGNNLlnDNYGLAIIILVLVIRIILLPFMLSNYKNShmmrQKMKVAKPEVEKIQEKVKrartq 109
Cdd:COG0706 4 GWFG-FIAKPLFWLLNFLHSLV--GNWGLAIILLTLIVRLLLFPLTVKQYKSM----AKMQELQPELKEIQEKYK----- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 110 EEKMAANQELMQVYKKYDMNPiksMLGCLPMLIQLPIIMGLYFVLKDqLVDglFKYPHFLWF-DLGRPD---IWITIIAG 185
Cdd:COG0706 72 DDPQKLQQEMMKLYKEEGVNP---LGGCLPMLIQMPIFIALYRVLRN-SIE--LRHAPFLGIpDLSAPDpyyIFLPILMG 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578583608 186 VLYFIQAYVSSKTMPDEQRQMgymMMVISPIMIIWISLSSASALGLYWSVSAAFLVVQTHFANIYYEK 253
Cdd:COG0706 146 VTMFLQQKLNPAPAQDPQQKK---MMYIMPLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLIINRRLDK 210
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
73-248 |
1.90e-46 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 154.07 E-value: 1.90e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 73 PFMLSNYKNShmmrQKMKVAKPEVEKIQEKVKRArtqeeKMAANQELMQVYKKYDMNPiksMLGCLPMLIQLPIIMGLYF 152
Cdd:cd20070 17 PLTLKQYKSM----KKMQELQPKIKEIQEKYKDD-----KQKLQQEMMKLYKEHGVNP---LGGCLPLLIQMPIFIALYQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 153 VLkdqLVDGLFKYPHFLWF--DLGRPDIW--ITIIAGVLYFIQAYVSSKTMPDEQRQMGyMMMVISPIMIIWISLSSASA 228
Cdd:cd20070 85 VL---RNSIELRGAPFLWWilDLSAPDPYyiLPILMGVTMFLQQKLTPTPTDDQAPQQK-MMMYFMPVMFTFIFLSFPSG 160
|
170 180
....*....|....*....|
gi 578583608 229 LGLYWSVSAAFLVVQTHFAN 248
Cdd:cd20070 161 LVLYWLVSNLFSIIQQLIIN 180
|
|
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
73-248 |
2.94e-41 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 141.07 E-value: 2.94e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 73 PFMLSNYKNShmmrQKMKVAKPEVEKIQEKVKrartqEEKMAANQELMQVYKKYDMNPiksMLGCLPMLIQLPIIMGLYF 152
Cdd:pfam02096 18 PLTYKQYKSM----AKMQELQPEMKEIQEKYK-----DDRQKLQQEMMKLYKKEGVNP---LGGCLPMLIQMPIFIALYR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 153 VLkdQLVDGLFKYPHFLWF-DLGRPDIWIT-------IIAGVLYFIQAYVSSkTMPDEQRQMGYMMMVISPIMIIWISLS 224
Cdd:pfam02096 86 VL--RNSIELRHAPFFLWIaDLSAPDPISIlhyyilpILMGVTMFLQQKLTP-APQDQPPQMKMMMLYFMPLMFLFFFLN 162
|
170 180
....*....|....*....|....
gi 578583608 225 SASALGLYWSVSAAFLVVQTHFAN 248
Cdd:pfam02096 163 FPAGLVLYWVVSNLLSIGQQLIIN 186
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK02463 |
PRK02463 |
OxaA-like protein precursor; Provisional |
1-243 |
5.82e-58 |
|
OxaA-like protein precursor; Provisional
Pssm-ID: 235040 Cd Length: 307 Bit Score: 188.02 E-value: 5.82e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 1 MKKK----ALLPLFLGIMVFLAGC-DYSKPEKRSGFFYNTFVDPMKNVLDWLGNNLlNDNYGLAIIILVLVIRIILLPFM 75
Cdd:PRK02463 1 MKKTlkriLFSGLALSMLLTLTGCvGRDKHGNPTGFIWNFLGAPMSYFIDYFANNL-GLGFGLAIIIVTIIVRLIILPLG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 76 LSNYKNSHMMRQKMKVAKPEVEKIQEKVKRARTQEEKMAANQELMQVYKKYDMNPIKSMlGCLPMLIQLPIIMGLYFVLk 155
Cdd:PRK02463 80 LYQSWKATYQSEKMAYLKPVFEPINERLKNATTQEEKMAAQTELMAAQRENGISMLGGI-GCLPLLIQMPFFSALYFAA- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 156 dQLVDGLFKyPHFLWFDLGRPDIWITIIAGVLYFIQAYVSSKTMPDEQRQMGYMMMVISPIMIIWISLSSASALGLYWSV 235
Cdd:PRK02463 158 -QYTKGVST-STFLGIDLGSPSLVLTAIIGVLYFFQSWLSMMGVPEEQREQMKAMMYMMPIMMVVFSFSSPAGVGLYWLV 235
|
....*...
gi 578583608 236 SAAFLVVQ 243
Cdd:PRK02463 236 GGFFSIIQ 243
|
|
| PRK01622 |
PRK01622 |
membrane protein insertase YidC; |
2-256 |
2.01e-55 |
|
membrane protein insertase YidC;
Pssm-ID: 179310 Cd Length: 256 Bit Score: 179.56 E-value: 2.01e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 2 KKKALLPLFLGIMVFLAGCDYSKPEKRS--GFFYNTFVDPMKNVLDWLGNnLLNDNYGLAIIILVLVIRIILLPFMLSNY 79
Cdd:PRK01622 5 YRAVLVSLSLLLVLVLSGCSNAAPIDAHsdGFFDHYFVYPFSFLIQFVAH-HIGGSYGIAIIIVTLIIRSLMIPLAVSQY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 80 KNSHMMRQKMKVAKPEVEKIQEKVKRARTQEEKMAANQELMQVYKKYDMNPIKsmLGCLPMLIQLPIIMGLYFVLKDQlv 159
Cdd:PRK01622 84 KSQRGMQEKMAVMKPELDKIQAKLKVTKDLEKQKEYQKEMMELYKSGNINPLA--MGCLPLLIQMPILSAFYYAIRRT-- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 160 dGLFKYPHFLWFDLGRPDIWITIIAGVLYFIQAYVS-SKTMPDEQRQMGYMMMVISPIMIIWISLSSASALGLYWSVSAA 238
Cdd:PRK01622 160 -EEIASHSFLWFNLGHADHILPIIAGLTYFIQMKVSqSNGTSPEQVQMLKIQGIMMPAMILFMSFAAPSALVLYWITGGL 238
|
250
....*....|....*...
gi 578583608 239 FLVVQTHFANIYYEKVAK 256
Cdd:PRK01622 239 FLMGQTIVLRKVMEREEK 256
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
73-246 |
3.62e-48 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 158.41 E-value: 3.62e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 73 PFMLSNYKNShmmrQKMKVAKPEVEKIQEKVKrartqEEKMAANQELMQVYKKYDMNPiksMLGCLPMLIQLPIIMGLYF 152
Cdd:TIGR03592 19 PLTLKQYKSM----RKMQELQPKLKEIQEKYK-----EDPQKLQQEMMKLYKEEGVNP---LGGCLPLLIQMPIFIALYQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 153 VLkdqLVDGLFKYPHFLW-FDLGRPDIW--ITIIAGVLYFIQAYVSSKTMPDEQRQmgYMMMVISPIMIIWISLSSASAL 229
Cdd:TIGR03592 87 VL---LRSIELRHAPFLWiIDLSSPDPYyiLPILMGVTMFLQQKLSPKGPPDPAQQ--KMMMYFMPLMFLFFFLSFPAGL 161
|
170
....*....|....*..
gi 578583608 230 GLYWSVSAAFLVVQTHF 246
Cdd:TIGR03592 162 VLYWVVSNLFTIIQQLI 178
|
|
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
30-253 |
7.35e-47 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 156.05 E-value: 7.35e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 30 GFFYnTFVDPMKNVLDWLGNNLlnDNYGLAIIILVLVIRIILLPFMLSNYKNShmmrQKMKVAKPEVEKIQEKVKrartq 109
Cdd:COG0706 4 GWFG-FIAKPLFWLLNFLHSLV--GNWGLAIILLTLIVRLLLFPLTVKQYKSM----AKMQELQPELKEIQEKYK----- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 110 EEKMAANQELMQVYKKYDMNPiksMLGCLPMLIQLPIIMGLYFVLKDqLVDglFKYPHFLWF-DLGRPD---IWITIIAG 185
Cdd:COG0706 72 DDPQKLQQEMMKLYKEEGVNP---LGGCLPMLIQMPIFIALYRVLRN-SIE--LRHAPFLGIpDLSAPDpyyIFLPILMG 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578583608 186 VLYFIQAYVSSKTMPDEQRQMgymMMVISPIMIIWISLSSASALGLYWSVSAAFLVVQTHFANIYYEK 253
Cdd:COG0706 146 VTMFLQQKLNPAPAQDPQQKK---MMYIMPLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLIINRRLDK 210
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
73-248 |
1.90e-46 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 154.07 E-value: 1.90e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 73 PFMLSNYKNShmmrQKMKVAKPEVEKIQEKVKRArtqeeKMAANQELMQVYKKYDMNPiksMLGCLPMLIQLPIIMGLYF 152
Cdd:cd20070 17 PLTLKQYKSM----KKMQELQPKIKEIQEKYKDD-----KQKLQQEMMKLYKEHGVNP---LGGCLPLLIQMPIFIALYQ 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 153 VLkdqLVDGLFKYPHFLWF--DLGRPDIW--ITIIAGVLYFIQAYVSSKTMPDEQRQMGyMMMVISPIMIIWISLSSASA 228
Cdd:cd20070 85 VL---RNSIELRGAPFLWWilDLSAPDPYyiLPILMGVTMFLQQKLTPTPTDDQAPQQK-MMMYFMPVMFTFIFLSFPSG 160
|
170 180
....*....|....*....|
gi 578583608 229 LGLYWSVSAAFLVVQTHFAN 248
Cdd:cd20070 161 LVLYWLVSNLFSIIQQLIIN 180
|
|
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
73-248 |
2.94e-41 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 141.07 E-value: 2.94e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 73 PFMLSNYKNShmmrQKMKVAKPEVEKIQEKVKrartqEEKMAANQELMQVYKKYDMNPiksMLGCLPMLIQLPIIMGLYF 152
Cdd:pfam02096 18 PLTYKQYKSM----AKMQELQPEMKEIQEKYK-----DDRQKLQQEMMKLYKKEGVNP---LGGCLPMLIQMPIFIALYR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 153 VLkdQLVDGLFKYPHFLWF-DLGRPDIWIT-------IIAGVLYFIQAYVSSkTMPDEQRQMGYMMMVISPIMIIWISLS 224
Cdd:pfam02096 86 VL--RNSIELRHAPFFLWIaDLSAPDPISIlhyyilpILMGVTMFLQQKLTP-APQDQPPQMKMMMLYFMPLMFLFFFLN 162
|
170 180
....*....|....*....|....
gi 578583608 225 SASALGLYWSVSAAFLVVQTHFAN 248
Cdd:pfam02096 163 FPAGLVLYWVVSNLLSIGQQLIIN 186
|
|
| PRK02944 |
PRK02944 |
YidC family membrane integrase SpoIIIJ; |
1-246 |
9.34e-36 |
|
YidC family membrane integrase SpoIIIJ;
Pssm-ID: 179508 Cd Length: 255 Bit Score: 128.73 E-value: 9.34e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 1 MKKK-ALLPLFLGIMVFLAGC-DYSKP--EKRSGFFYNTFVDPMKNVLDWLGNnLLNDNYGLAIIILVLVIRIILLPFML 76
Cdd:PRK02944 1 MKKKlGLLAMVVALMAILAGCsEVNQPitPKSTGFWNEYFVYPLSQLITYFAN-LFGSNYGLAIIVVTLLIRLLILPLMI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 77 SNYKNShmmrQKMKVAKPEVEKIQEKV--KRARTQEEkmaANQELMQVYKKYDMNPiksMLGCLPMLIQLPIIMGLYFVL 154
Cdd:PRK02944 80 KQTKST----KAMQALQPEMQKLKEKYssKDQATQQK---LQQEMMQLFQKNGVNP---LAGCLPIFIQMPILIAFYHAI 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 155 kdqLVDGLFKYPHFLWFDLGRPDIW--ITIIAGVLYFIQAYVSSKTMPDEQRQMGyMMMVISPIMIIWISLSSASALGLY 232
Cdd:PRK02944 150 ---MRTSEISKHSFLWFDLGQADPYyiLPIVAGITTFIQQKLMMAGTAGQNPQMA-MMLWLMPIMILIFAINFPAALSLY 225
|
250
....*....|....
gi 578583608 233 WSVSAAFLVVQTHF 246
Cdd:PRK02944 226 WVVGNIFMIAQTYL 239
|
|
| PRK00145 |
PRK00145 |
putative inner membrane protein translocase component YidC; Provisional |
34-248 |
9.29e-29 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234665 [Multi-domain] Cd Length: 223 Bit Score: 109.45 E-value: 9.29e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 34 NTFVDPMKNVLDWLGNNLLNDN--YGLAIIILVLVIRIILLPFMLSNYKNShmmrQKMKVAKPEVEKIQEKVKrartqEE 111
Cdd:PRK00145 7 NAFVQFFKFIHGFVSSVISNPNfsYGIAIILVTLIIRLLILPLNIKQTKSS----LRMNEIQPEIKKLQAKYK-----ND 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 112 KMAANQELMQVYKKYDMNPiksMLGCLPMLIQLPIIMGLYFVLKD-QLVDGLfkypHFLWF-DLGRPDI-WI-TIIAGVL 187
Cdd:PRK00145 78 PQKLQQEMMKLYKEKGVNP---LGGCLPLLIQWPILIALYYVFNNlTGINGV----SFLWIkDLAKPDItWIlPILSGAT 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578583608 188 YFIQAYVSSKTMPDEQRQMGYMMMVISpIMIIWISLSSASALGLYWSVSAAFLVVQTHFAN 248
Cdd:PRK00145 151 TYLSGYLMTKADSSQAGQMKTMNIGMS-IFMGVMSWKFKSALVLYWVIGNLIQIIQTYFIK 210
|
|
| 5TM_Oxa1-like |
cd20069 |
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar ... |
88-244 |
3.63e-25 |
|
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar proteins; This group is composed mostly of the mitochondrial members of the YidC/Oxa1/Alb3 protein family of insertases, including mitochondrial inner membrane proteins Oxa1, Oxa1-like (Oxa1L), cytochrome c oxidase assembly protein 18 (Cox18, also called Oxa2), and Arabidopsis thaliana mitochondrial ALBINO3-like protein 3 (ALB33). It also includes Arabidopsis thaliana chloroplastic ALBINO3-like protein 2 (ALB32). Members of this group mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Oxa1 and Cox18/Oxa2 are essential for the activity and assembly of cytochrome c oxidase, playing central roles in the translocation and export of the N-terminal and C-terminal parts, respectively, of the COX2 protein into the mitochondrial intermembrane space. ALB32 may be involved in the insertion of integral membrane proteins into the chloroplast thylakoid membranes. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410993 [Multi-domain] Cd Length: 201 Bit Score: 99.52 E-value: 3.63e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 88 KMKVAKPEVEKIQEKVKRART---QEEKMAANQELMQVYKKYDMNPIKSMlgcLPMLIQLPIIMGLYFVLK---DQLVDG 161
Cdd:cd20069 32 RMANLQPELQKLQEKLKEARAsgdQLEAAEARKELKELMKKHNVNPLKSL---LLPLVQAPVFISFFFALRkmaNLPVPS 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 162 lFKYPHFLWF-DLGRPD-IWI-TIIAGVLYFIQAYVSSKTMPDEQRQMGYM--MMVISPIMIIWISLSSASALGLYWSVS 236
Cdd:cd20069 109 -FKTGGLLWFtDLTVPDpYYIlPILTSLTFLATIELGAETGTSGSPQSKTMknVFRGLPVLMIPFTANFPSAVFLYWITS 187
|
....*...
gi 578583608 237 AAFLVVQT 244
Cdd:cd20069 188 NLFSLAQN 195
|
|
| PRK01318 |
PRK01318 |
membrane protein insertase; Provisional |
87-243 |
3.74e-22 |
|
membrane protein insertase; Provisional
Pssm-ID: 234942 [Multi-domain] Cd Length: 521 Bit Score: 95.71 E-value: 3.74e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 87 QKMKVAKPEVEKIQEKVKrartqEEKMAANQELMQVYKKYDMNPiksMLGCLPMLIQLPIIMGLYFVlkdqlvdgLFKY- 165
Cdd:PRK01318 350 AKMKVLQPKMQELKEKYK-----DDPQKMQQEMMELYKKEKVNP---LGGCLPILIQIPIFFALYKV--------LLVSi 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 166 -----PHFLWF-DLGRPD---IWITIIAGVLYFIQAYVSSKTMPDEQRQMGYMMMVISPIMIIWISLSSASALGLYWSVS 236
Cdd:PRK01318 414 elrhaPFIGWIhDLSAPDpyfILHIGLLPILMGITMFLQQKLNPTPTDPMQAKIMKFMPLIFTFFFLSFPAGLVLYWIVN 493
|
....*..
gi 578583608 237 AAFLVVQ 243
Cdd:PRK01318 494 NLLTIIQ 500
|
|
| 5TM_YidC_Oxa1_Alb3 |
cd19751 |
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1 ... |
73-246 |
1.11e-21 |
|
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1/Alb3 protein family of insertases facilitate the insertion, folding and assembly of proteins of the inner membranes of bacteria and mitochondria, and the thylakoid membrane of plastids. Members include bacterial YidC, mitochondrial Cox18 and Oxa1, and chloroplastic Alb3 and Alb4. Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Oxa1 and Cox18/Oxa2 mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Alb3 and Alb3-like proteins, including Alb4, are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410992 [Multi-domain] Cd Length: 189 Bit Score: 89.92 E-value: 1.11e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 73 PFMLSNYKNShmmrQKMKVAKPEVEKIQEKVKRARTQEEKMA-ANQELMQVYKKYDMNPiksMLGCLPMLIQLPIIMGLY 151
Cdd:cd19751 17 PLTLKQQKSM----RKMQVIRPEMEAIREKYKEKASKDKVQQeMQKEMLGLYKKHGVNP---MAGCLPLFIQLPIFMAFY 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 152 FVLKDQLVdglFKYPHFLWF-DLGRPDIW--ITIIAGVLYFIQAYVSSKTMPDEQRQMGYM--MMVISPIMIIWISLSSA 226
Cdd:cd19751 90 FAIMRTEE---IRYHTFLWFfDLGQPDYLyiLPFVAGITTYFQFKMTMSHQQQMQMMQMQMkvMLYVMPVMIIIAGLSFP 166
|
170 180
....*....|....*....|
gi 578583608 227 SALGLYWSVSAAFLVVQTHF 246
Cdd:cd19751 167 SALSLYWIISNLFMIIQTYF 186
|
|
| PRK01001 |
PRK01001 |
putative inner membrane protein translocase component YidC; Provisional |
85-261 |
2.32e-18 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234887 [Multi-domain] Cd Length: 795 Bit Score: 84.85 E-value: 2.32e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 85 MRqKMKVAKPEVEKIQEKVKRartqeEKMAANQELMQVYKKYDMNPIKsmlGCLPMLIQLPIIMGLYFVLK--------- 155
Cdd:PRK01001 602 MR-RMQKLSPYIQEIQQKYKK-----EPKRAQMEIMALYKTNKVNPIT---GCLPLLIQLPFLIAMFDLLKssfllrgas 672
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 156 ------DQLV--DGLFKYPHFLWFdLGRPDIWITIIAGVLYFIQAYVSSKT----MPDEQRQ---MGYMMMVISPIMIiw 220
Cdd:PRK01001 673 fipgwiDNLTapDVLFSWETPIWF-IGNEFHLLPILLGVVMFAQQKISSLKrkgpVTDQQRQqeaMGTMMALLFTFMF-- 749
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 578583608 221 isLSSASALGLYWSVSAAFLVVQTHFAN-IYYEKVAKKEVQP 261
Cdd:PRK01001 750 --YNFPSGLNIYWLSSMLLGVIQQWVTNkILDSKHLKNEVVP 789
|
|
| PRK01315 |
PRK01315 |
putative inner membrane protein translocase component YidC; Provisional |
88-236 |
1.97e-14 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234941 Cd Length: 329 Bit Score: 72.08 E-value: 1.97e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 88 KMKVAKPEVEKIQEKVKRARtqeEKMaaNQELMQVYKKYDMNPIKSmlgCLPMLIQLPIIMGLYFVLKDQLVDGL----- 162
Cdd:PRK01315 70 NMQEIQPKMKKIQEKYKGDR---ERM--SQEMMKLYKETGTNPLSS---CLPLLLQMPIFFALYRVLDSAASRGDgigpi 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 163 -------FKYPHFL--------WFDLGRPDIWITIIAGVL--------YFIQAYVSSKTMPDE-----QRQMGYMMMVIS 214
Cdd:PRK01315 142 nppllesFRHAHIFgaplaatfLQALNAGNTAVQVVAAVLiilmsasqFITQLQLMTKNMPPEaktgpMAQQQKMLLYLF 221
|
170 180
....*....|....*....|..
gi 578583608 215 PIMIIWISLSSASALGLYWSVS 236
Cdd:PRK01315 222 PLMFLVSGIAFPVGVLFYWLTS 243
|
|
| PRK03449 |
PRK03449 |
putative inner membrane protein translocase component YidC; Provisional |
83-258 |
2.10e-10 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 179580 Cd Length: 304 Bit Score: 60.08 E-value: 2.10e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 83 HMMR--QKMKVAKPEVEKIQEKVKRARTqeeKMAanQELMQVYKKYDMNPIksmLGCLPMLIQLPIIMGLYFVLKD---- 156
Cdd:PRK03449 53 RQIRttRKMQELQPQIKALQKKYGNDRQ---KMA--LEMQKLQKEHGFNPI---LGCLPMLAQIPVFLGLFHVLRSfnrt 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 157 ----------------------------QLVDG-LFKYPHFLW-----------FDLGRPDIWIT-----IIAGVLYFIQ 191
Cdd:PRK03449 125 gtgfgqlgmsveenrntpnyvfsaedvqSFLDArLFGAPLSAYitmprsgldafVDFTRTNIILVgvplmIIAGVATHFN 204
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578583608 192 AYVSSKTMPDEQRQ------MGYMMMVISPIMIIWISLSSASALGLYWSVSAAFLVVQTH--FANIYYEKVAKKE 258
Cdd:PRK03449 205 SRASVARQSAEAAAnpqtamMNKLALWVFPLGVLVGGPFLPLAILLYWVSNNIWTFGQQHyvFGKIDKEEEAKKQ 279
|
|
| PRK00247 |
PRK00247 |
putative inner membrane protein translocase component YidC; Validated |
73-154 |
6.21e-06 |
|
putative inner membrane protein translocase component YidC; Validated
Pssm-ID: 178945 [Multi-domain] Cd Length: 429 Bit Score: 47.15 E-value: 6.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 73 PFMLSNYKNSH---MMRQKMKVAKPEV-EKIQEKVKRARTQEEKmaanqelmQVYKKYDMNPIKsmlGCLPMLIQLPIIM 148
Cdd:PRK00247 49 PFTWQQYKSGRtaaHIRPKRKALREEYkGKTDEASIRELQQKQK--------DLNKEYGYNPLA---GCVPALIQIPVFL 117
|
....*.
gi 578583608 149 GLYFVL 154
Cdd:PRK00247 118 GLYQVL 123
|
|
| PRK02654 |
PRK02654 |
putative inner membrane protein translocase component YidC; Provisional |
55-155 |
7.40e-06 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235058 Cd Length: 375 Bit Score: 46.90 E-value: 7.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 55 NYGLAIIILVLVIRIILLPFMLSNYKNshmMRqKMKVAKPEVEKIQEKVK-RARTQEEKMaaNQELMQVYKKYDmNPIKs 133
Cdd:PRK02654 26 SYGLAIVALTLVIRFALYPLSAGSIRN---MR-RMKIAQPVMQKRQAEIQeRYKNDPQKQ--QEEMGKLMKEFG-NPLA- 97
|
90 100
....*....|....*....|..
gi 578583608 134 mlGCLPMLIQLPIIMGLYFVLK 155
Cdd:PRK02654 98 --GCLPLLVQMPILFALFATLR 117
|
|
| PHA00368 |
PHA00368 |
internal virion protein D |
183-230 |
2.18e-05 |
|
internal virion protein D
Pssm-ID: 222785 [Multi-domain] Cd Length: 1315 Bit Score: 45.93 E-value: 2.18e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 578583608 183 IAGVLYFIQAYVSSKTMPDEQRQmGYMMMVISPIMIIWISLSSASALG 230
Cdd:PHA00368 1144 LAGGYYVAQAHVKAYGLPEEQRK-EYLKNALDPTMIAYAALSRSSHLG 1190
|
|
| PRK02201 |
PRK02201 |
putative inner membrane protein translocase component YidC; Provisional |
30-265 |
3.27e-05 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235012 Cd Length: 357 Bit Score: 44.62 E-value: 3.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 30 GFFYNTFVDPMKNVLDWLGNNL-LNDNYG----LAIIILVLVIRIillpFMLSNYKNSHMMRQKMKVAKPEVEKIQEKVK 104
Cdd:PRK02201 102 GPFYGLFVYPIAQIILSIMASQsLSELYGwstiLAIIVVVLIIRL----ISFLITFKSTFNQEKQEELQGKKAKIDAKYK 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 105 RARTQEE-KMAANQELMQVYKKYDMNPIKSMlgcLPMLIQLPIIMGLYFVlkdqlVDGL--FKYPHFLWFDL-------- 173
Cdd:PRK02201 178 DYKKDKQmKQRKQQEIQELYKKHNISPFSPF---VQMFVTLPIFIAVYRV-----VQSLpsIKVTTWLGIDLsatswqei 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578583608 174 ---GRPDIWITIIAGVLYFIQAYV----------SSKTMPDEQRQM--GYMMMVISPIMIIWISLSSASALGLYWSVSAA 238
Cdd:PRK02201 250 fagNWIYLPILIIVVPVQALSQLLpqilnkkknkERTLNVKEKEALkkQNKTQNIISIVFIFFGVIFAAGVQIYWIIGGI 329
|
250 260 270
....*....|....*....|....*....|
gi 578583608 239 FLVVQTHFanIYYEKVAKK---EVQPFIEA 265
Cdd:PRK02201 330 WTILQTLG--IHYFKKRKFykqKYEPKLRA 357
|
|
| |
