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Conserved domains on  [gi|577502695|gb|EUH15710|]
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phage protein [Staphylococcus aureus M0088]

Protein Classification

PVL_ORF50 domain-containing protein( domain architecture ID 10544297)

PVL_ORF50 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PVL_ORF50 pfam07768
PVL ORF-50-like family; This is a family of sequences found in both bacteria and ...
 7-119 1.20e-43

PVL ORF-50-like family; This is a family of sequences found in both bacteria and bacteriophages. This region is approximately 130 residues long and in some cases is found as part of the PVL (Panton-Valentine leukocidin) group of genes, which encode a member of the leukocidin group of bacterial toxins that kill leukocytes by creation of pores in the cell membrane. PVL appears to be a virulence factor associated with a number of human diseases.


:

Pssm-ID: 285065  Cd Length: 116  Bit Score: 138.55  E-value: 1.20e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577502695    7 IVTINDKPYRFSKFEMELIESHGITAGMVSKRVKDGWELHEAMDAPEGTRLSEYREKKTIERLEQARLERKLERKRKREA 86
Cdd:pfam07768   1 IVRIRIKPYLFTLREVELIEKYGITPGMVRKRVKHGWRLDEALCAPKGSRLKEYVEYMKSQIKEEEKGERKIRRQRNVEA 80

                          90       100       110
                  ....*....|....*....|....*....|...
gi 577502695   87 ELRRKKPHLFNVPQKHPRGRYACYLLENDIFVK 119
Cdd:pfam07768  81 ELRRKKPHLFNVPQKHSRDPYWFDVTYNQMFKK 113
 
Name Accession Description Interval E-value
PVL_ORF50 pfam07768
PVL ORF-50-like family; This is a family of sequences found in both bacteria and ...
 7-119 1.20e-43

PVL ORF-50-like family; This is a family of sequences found in both bacteria and bacteriophages. This region is approximately 130 residues long and in some cases is found as part of the PVL (Panton-Valentine leukocidin) group of genes, which encode a member of the leukocidin group of bacterial toxins that kill leukocytes by creation of pores in the cell membrane. PVL appears to be a virulence factor associated with a number of human diseases.


Pssm-ID: 285065  Cd Length: 116  Bit Score: 138.55  E-value: 1.20e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577502695    7 IVTINDKPYRFSKFEMELIESHGITAGMVSKRVKDGWELHEAMDAPEGTRLSEYREKKTIERLEQARLERKLERKRKREA 86
Cdd:pfam07768   1 IVRIRIKPYLFTLREVELIEKYGITPGMVRKRVKHGWRLDEALCAPKGSRLKEYVEYMKSQIKEEEKGERKIRRQRNVEA 80

                          90       100       110
                  ....*....|....*....|....*....|...
gi 577502695   87 ELRRKKPHLFNVPQKHPRGRYACYLLENDIFVK 119
Cdd:pfam07768  81 ELRRKKPHLFNVPQKHSRDPYWFDVTYNQMFKK 113
 
Name Accession Description Interval E-value
PVL_ORF50 pfam07768
PVL ORF-50-like family; This is a family of sequences found in both bacteria and ...
 7-119 1.20e-43

PVL ORF-50-like family; This is a family of sequences found in both bacteria and bacteriophages. This region is approximately 130 residues long and in some cases is found as part of the PVL (Panton-Valentine leukocidin) group of genes, which encode a member of the leukocidin group of bacterial toxins that kill leukocytes by creation of pores in the cell membrane. PVL appears to be a virulence factor associated with a number of human diseases.


Pssm-ID: 285065  Cd Length: 116  Bit Score: 138.55  E-value: 1.20e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577502695    7 IVTINDKPYRFSKFEMELIESHGITAGMVSKRVKDGWELHEAMDAPEGTRLSEYREKKTIERLEQARLERKLERKRKREA 86
Cdd:pfam07768   1 IVRIRIKPYLFTLREVELIEKYGITPGMVRKRVKHGWRLDEALCAPKGSRLKEYVEYMKSQIKEEEKGERKIRRQRNVEA 80

                          90       100       110
                  ....*....|....*....|....*....|...
gi 577502695   87 ELRRKKPHLFNVPQKHPRGRYACYLLENDIFVK 119
Cdd:pfam07768  81 ELRRKKPHLFNVPQKHSRDPYWFDVTYNQMFKK 113
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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