|
Name |
Accession |
Description |
Interval |
E-value |
| LCB5 |
COG1597 |
Phosphatidylglycerol kinase, diacylglycerol kinase family [Lipid transport and metabolism, ... |
9-301 |
2.47e-70 |
|
Phosphatidylglycerol kinase, diacylglycerol kinase family [Lipid transport and metabolism, General function prediction only];
Pssm-ID: 441205 [Multi-domain] Cd Length: 295 Bit Score: 219.72 E-value: 2.47e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 9 VLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKtknyAKDVDILFILGGDGTVNELINGVMSH 88
Cdd:COG1597 6 LLIVNPASGRGRAARLLERLVAALRAAGLEVEVLETESPGDATELAREAA----AEGADLVVAAGGDGTVNEVANGLAGT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 89 DLqlPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLS 168
Cdd:COG1597 82 GP--PLGILPLGTGNDFARALGIPLDPEAALEALLTGRTRRIDLGRVNGRYFLNVAGIGFDAEVVERANRALKRRLGKLA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 169 YIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQS----FSILNDIFK 244
Cdd:COG1597 160 YVLAALRALLRYRPFRLRIELDGEEIEGEALLVAVGNGPYYGGGLRLAPDASLDDGLLDVVVVRPLSrlrlLRLLPRLLR 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 577414180 245 KRDSMNwneitQGIEHIPGKKISLTTDPAMKVDIDGEI-SLETPIDIEVIPNAIQLLT 301
Cdd:COG1597 240 GRHLRH-----PGVRYFRAREVEIESDRPLPVQLDGEPlGLATPLEFEVLPGALRVLV 292
|
|
| TIGR00147 |
TIGR00147 |
lipid kinase, YegS/Rv2252/BmrU family; The E. coli member of this family, YegS has been ... |
7-301 |
3.95e-46 |
|
lipid kinase, YegS/Rv2252/BmrU family; The E. coli member of this family, YegS has been purified and shown to have phosphatidylglycerol kinase activity. The member from M. tuberculosis, Rv2252, has diacylglycerol kinase activity. BmrU from B. subtilis is in an operon with multidrug efflux transporter Bmr, but is uncharacterized. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 161732 [Multi-domain] Cd Length: 293 Bit Score: 157.28 E-value: 3.95e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 7 HGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNyakdVDILFILGGDGTVNELINGVM 86
Cdd:TIGR00147 3 EAPAILNPTAGKSNDNKPLREVIMLLREEGMEIHVRVTWEKGDAARYVEEARKFG----VDTVIAGGGDGTINEVVNALI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 87 SHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYA-LNFVGLGLIVQNAENVQDGSKDIFG 165
Cdd:TIGR00147 79 QLDDIPALGILPLGTANDFARSLGIPEDLDKAAKLVIAGDARAIDMGQVNKQYCfINMAGGGFGTEITTETPEKLKAALG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 166 KLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKK 245
Cdd:TIGR00147 159 SLSYILSGLMRMDTLQPFRCEIRGEGEHWQGEAVVFLVGNGRQAGGGQKLAPDASINDGLLDLRIFTNDNLLPALVLTLM 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 577414180 246 RDSmNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLT 301
Cdd:TIGR00147 239 SDE-GKHTDNPNIIYGKASRIDIQTPHKITFNLDGEPLGGTPFHIEILPAHLRCRL 293
|
|
| DAGK_cat |
pfam00781 |
Diacylglycerol kinase catalytic domain; Diacylglycerol (DAG) is a second messenger that acts ... |
7-135 |
2.04e-34 |
|
Diacylglycerol kinase catalytic domain; Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. The catalytic domain is assumed from the finding of bacterial homologs. YegS is the Escherichia coli protein in this family whose crystal structure reveals an active site in the inter-domain cleft formed by four conserved sequence motifs, revealing a novel metal-binding site. The residues of this site are conserved across the family.
Pssm-ID: 425868 [Multi-domain] Cd Length: 125 Bit Score: 121.54 E-value: 2.04e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 7 HGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYakdvDILFILGGDGTVNELINGVM 86
Cdd:pfam00781 1 KLLVIVNPKSGGGKGKKLLRKVRPLLNKAGVEVELVLTEGPGDALELAREAAEDGY----DRIVVAGGDGTVNEVLNGLA 76
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 577414180 87 SHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKI 135
Cdd:pfam00781 77 GLATRPPLGIIPLGTGNDFARALGIPGDPEEALEAILKGQTRPVDVGKV 125
|
|
| PRK13057 |
PRK13057 |
lipid kinase; |
62-300 |
4.62e-29 |
|
lipid kinase;
Pssm-ID: 183857 [Multi-domain] Cd Length: 287 Bit Score: 112.32 E-value: 4.62e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 62 YAKDVDILFILGGDGTVNELINGVMshDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYAL 141
Cdd:PRK13057 47 YADGVDLVIVGGGDGTLNAAAPALV--ETGLPLGILPLGTANDLARTLGIPLDLEAAARVIATGQVRRIDLGWVNGHYFF 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 142 NFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSP 221
Cdd:PRK13057 125 NVASLGLSAELARRLTKELKRRWGTLGYAIAALRVLRRSRPFTAEIEHDGRTERVKTLQVAVGNGRYYGGGMTVAHDATI 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 222 QDGELNTFIFNEQS----FSILNDIFKKRDSmNWNEITqgieHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAI 297
Cdd:PRK13057 205 DDGRLDLYSLEVAHwwrlLALLPALRRGRHG-EWPDVR----AFRTTELELRTRKPRPINTDGELTTYTPAHFRVLPKAL 279
|
...
gi 577414180 298 QLL 300
Cdd:PRK13057 280 RVL 282
|
|
| DAGKc |
smart00046 |
Diacylglycerol kinase catalytic domain (presumed); Diacylglycerol (DAG) is a second messenger ... |
62-111 |
4.36e-09 |
|
Diacylglycerol kinase catalytic domain (presumed); Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. DAG can be produced from the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) by a phosphoinositide-specific phospholipase C and by the degradation of phosphatidylcholine (PC) by a phospholipase C or the concerted actions of phospholipase D and phosphatidate phosphohydrolase. This domain is presumed to be the catalytic domain. Bacterial homologues areknown.
Pssm-ID: 214487 [Multi-domain] Cd Length: 124 Bit Score: 53.84 E-value: 4.36e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 577414180 62 YAKDVDI---LFILGGDGTVNELINGVMSHDLQL---PIGILPGGTFNDFTKTLNI 111
Cdd:smart00046 43 IFRDVPDfnrVLVCGGDGTVGWVLNALDKRELPLpepPVAVLPLGTGNDLARSLGW 98
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LCB5 |
COG1597 |
Phosphatidylglycerol kinase, diacylglycerol kinase family [Lipid transport and metabolism, ... |
9-301 |
2.47e-70 |
|
Phosphatidylglycerol kinase, diacylglycerol kinase family [Lipid transport and metabolism, General function prediction only];
Pssm-ID: 441205 [Multi-domain] Cd Length: 295 Bit Score: 219.72 E-value: 2.47e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 9 VLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKtknyAKDVDILFILGGDGTVNELINGVMSH 88
Cdd:COG1597 6 LLIVNPASGRGRAARLLERLVAALRAAGLEVEVLETESPGDATELAREAA----AEGADLVVAAGGDGTVNEVANGLAGT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 89 DLqlPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLS 168
Cdd:COG1597 82 GP--PLGILPLGTGNDFARALGIPLDPEAALEALLTGRTRRIDLGRVNGRYFLNVAGIGFDAEVVERANRALKRRLGKLA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 169 YIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQS----FSILNDIFK 244
Cdd:COG1597 160 YVLAALRALLRYRPFRLRIELDGEEIEGEALLVAVGNGPYYGGGLRLAPDASLDDGLLDVVVVRPLSrlrlLRLLPRLLR 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 577414180 245 KRDSMNwneitQGIEHIPGKKISLTTDPAMKVDIDGEI-SLETPIDIEVIPNAIQLLT 301
Cdd:COG1597 240 GRHLRH-----PGVRYFRAREVEIESDRPLPVQLDGEPlGLATPLEFEVLPGALRVLV 292
|
|
| TIGR00147 |
TIGR00147 |
lipid kinase, YegS/Rv2252/BmrU family; The E. coli member of this family, YegS has been ... |
7-301 |
3.95e-46 |
|
lipid kinase, YegS/Rv2252/BmrU family; The E. coli member of this family, YegS has been purified and shown to have phosphatidylglycerol kinase activity. The member from M. tuberculosis, Rv2252, has diacylglycerol kinase activity. BmrU from B. subtilis is in an operon with multidrug efflux transporter Bmr, but is uncharacterized. [Unknown function, Enzymes of unknown specificity]
Pssm-ID: 161732 [Multi-domain] Cd Length: 293 Bit Score: 157.28 E-value: 3.95e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 7 HGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNyakdVDILFILGGDGTVNELINGVM 86
Cdd:TIGR00147 3 EAPAILNPTAGKSNDNKPLREVIMLLREEGMEIHVRVTWEKGDAARYVEEARKFG----VDTVIAGGGDGTINEVVNALI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 87 SHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYA-LNFVGLGLIVQNAENVQDGSKDIFG 165
Cdd:TIGR00147 79 QLDDIPALGILPLGTANDFARSLGIPEDLDKAAKLVIAGDARAIDMGQVNKQYCfINMAGGGFGTEITTETPEKLKAALG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 166 KLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKK 245
Cdd:TIGR00147 159 SLSYILSGLMRMDTLQPFRCEIRGEGEHWQGEAVVFLVGNGRQAGGGQKLAPDASINDGLLDLRIFTNDNLLPALVLTLM 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 577414180 246 RDSmNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLT 301
Cdd:TIGR00147 239 SDE-GKHTDNPNIIYGKASRIDIQTPHKITFNLDGEPLGGTPFHIEILPAHLRCRL 293
|
|
| DAGK_cat |
pfam00781 |
Diacylglycerol kinase catalytic domain; Diacylglycerol (DAG) is a second messenger that acts ... |
7-135 |
2.04e-34 |
|
Diacylglycerol kinase catalytic domain; Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. The catalytic domain is assumed from the finding of bacterial homologs. YegS is the Escherichia coli protein in this family whose crystal structure reveals an active site in the inter-domain cleft formed by four conserved sequence motifs, revealing a novel metal-binding site. The residues of this site are conserved across the family.
Pssm-ID: 425868 [Multi-domain] Cd Length: 125 Bit Score: 121.54 E-value: 2.04e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 7 HGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYakdvDILFILGGDGTVNELINGVM 86
Cdd:pfam00781 1 KLLVIVNPKSGGGKGKKLLRKVRPLLNKAGVEVELVLTEGPGDALELAREAAEDGY----DRIVVAGGDGTVNEVLNGLA 76
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 577414180 87 SHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKI 135
Cdd:pfam00781 77 GLATRPPLGIIPLGTGNDFARALGIPGDPEEALEAILKGQTRPVDVGKV 125
|
|
| PRK13057 |
PRK13057 |
lipid kinase; |
62-300 |
4.62e-29 |
|
lipid kinase;
Pssm-ID: 183857 [Multi-domain] Cd Length: 287 Bit Score: 112.32 E-value: 4.62e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 62 YAKDVDILFILGGDGTVNELINGVMshDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYAL 141
Cdd:PRK13057 47 YADGVDLVIVGGGDGTLNAAAPALV--ETGLPLGILPLGTANDLARTLGIPLDLEAAARVIATGQVRRIDLGWVNGHYFF 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 142 NFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSP 221
Cdd:PRK13057 125 NVASLGLSAELARRLTKELKRRWGTLGYAIAALRVLRRSRPFTAEIEHDGRTERVKTLQVAVGNGRYYGGGMTVAHDATI 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 222 QDGELNTFIFNEQS----FSILNDIFKKRDSmNWNEITqgieHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAI 297
Cdd:PRK13057 205 DDGRLDLYSLEVAHwwrlLALLPALRRGRHG-EWPDVR----AFRTTELELRTRKPRPINTDGELTTYTPAHFRVLPKAL 279
|
...
gi 577414180 298 QLL 300
Cdd:PRK13057 280 RVL 282
|
|
| PRK13059 |
PRK13059 |
putative lipid kinase; Reviewed |
67-304 |
3.59e-28 |
|
putative lipid kinase; Reviewed
Pssm-ID: 183858 Cd Length: 295 Bit Score: 110.13 E-value: 3.59e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 67 DILFILGGDGTVNELINGVMSHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGL 146
Cdd:PRK13059 58 KYILIAGGDGTVDNVVNAMKKLNIDLPIGILPVGTANDFAKFLGMPTDIGEACEQILKSKPKKVDLGKINDKYFINVAST 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 147 GLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIpLTDLSPQDGEL 226
Cdd:PRK13059 138 GLFTDVSQKTDVNLKNTIGKLAYYLKGLEELPNFRKLKVKVTSEEVNFDGDMYLMLVFNGQTAGNFNL-AYKAEVDDGLL 216
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 577414180 227 NTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVND 304
Cdd:PRK13059 217 DVIIIKACPIIDLIPLFIKVLKGEHLEDVNGLIYFKTDKLEIESNEEIVTDIDGERGPDFPLNIECIKGGLKVLGILD 294
|
|
| PRK00861 |
PRK00861 |
putative lipid kinase; Reviewed |
24-302 |
2.05e-21 |
|
putative lipid kinase; Reviewed
Pssm-ID: 234850 [Multi-domain] Cd Length: 300 Bit Score: 91.99 E-value: 2.05e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 24 GIGEVTTALSSICKHLSIQLsenEGDIIKYCQEIKTKNYAKD-----VDILFILGGDGTVNELINGVMSHDLqlPIGILP 98
Cdd:PRK00861 14 GQGNPEVDLALIRAILEPEM---DLDIYLTTPEIGADQLAQEaiergAELIIASGGDGTLSAVAGALIGTDI--PLGIIP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 99 GGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLL 178
Cdd:PRK00861 89 RGTANAFAAALGIPDTIEEACRTILQGKTRRVDVAYCNGQPMILLAGIGFEAETVEEADREAKNRFGILAYILSGLQQLR 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 179 NPTQFNYQLSIDDKTYSGETTMILTAN----------GPfiGGsripltdLSPQDGELNTFI-------------FNEQS 235
Cdd:PRK00861 169 ELESFEVEIETEDQIITTNAVAVTVANaapptsvlaqGP--GA-------VIPDDGLLDVTIvapknlaeavaasYHLLQ 239
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 577414180 236 FSILNDIFKKRDsmnwneitqgIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAiqlLTV 302
Cdd:PRK00861 240 TALQGNPAERDD----------IGYLRAKQVKITTDPPQKVVIDGEVVGTTPIEIECLPRS---LKV 293
|
|
| PRK13337 |
PRK13337 |
putative lipid kinase; Reviewed |
64-304 |
2.24e-20 |
|
putative lipid kinase; Reviewed
Pssm-ID: 183982 [Multi-domain] Cd Length: 304 Bit Score: 88.95 E-value: 2.24e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 64 KDVDILFILGGDGTVNELINGVMSHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNF 143
Cdd:PRK13337 56 RKFDLVIAAGGDGTLNEVVNGIAEKENRPKLGIIPVGTTNDFARALHVPRDIEKAADVIIEGHTVPVDIGKANNRYFINI 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 144 VGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTL--LNPTQFnyQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSP 221
Cdd:PRK13337 136 AGGGRLTELTYEVPSKLKTMLGQLAYYLKGIEMLpsLKATDV--RIEYDGKLFQGEIMLFLLGLTNSVGGFEKLAPDASL 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 222 QDGELNTFIFNEQSFSILNDIFkkrdsmnwneiTQGI--EHI--------PGKKISLTTDPAMKVDIDGEISLETPIDIE 291
Cdd:PRK13337 214 DDGYFDLIIVKKANLAELIHIA-----------TLALrgEHIkhpkviytKANRIKVSSFDKMQLNLDGEYGGKLPAEFE 282
|
250
....*....|...
gi 577414180 292 VIPNAIQLLTVND 304
Cdd:PRK13337 283 NLYRHIEVFVPKD 295
|
|
| PRK13055 |
PRK13055 |
putative lipid kinase; Reviewed |
67-298 |
6.01e-20 |
|
putative lipid kinase; Reviewed
Pssm-ID: 237282 [Multi-domain] Cd Length: 334 Bit Score: 88.12 E-value: 6.01e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 67 DILFILGGDGTVNELINGVMSHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMI-SAQVGTYDVIKINN-QYALNFV 144
Cdd:PRK13055 61 DLIIAAGGDGTINEVVNGIAPLEKRPKMAIIPAGTTNDYARALKIPRDNPVEAAKVIlKNQTIKMDIGRANEdKYFINIA 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 145 GLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDG 224
Cdd:PRK13055 141 AGGSLTELTYSVPSQLKSMFGYLAYLAKGAELLPRVSPVPVRITYDEGVFEGKISMFFLALTNSVGGFEQIVPDAKLDDG 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 225 ELNTFIFNEQS----FSILNDIFKKRDSMNwneiTQGIEHIPGKK--ISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQ 298
Cdd:PRK13055 221 KFTLIIVKTANlfelLHLMALILNGGKHID----DPRVIYIKTSKltIEPLGDDRLMVNLDGEYGGDAPMTFENLKQHIE 296
|
|
| PRK12361 |
PRK12361 |
hypothetical protein; Provisional |
66-301 |
4.99e-16 |
|
hypothetical protein; Provisional
Pssm-ID: 183473 [Multi-domain] Cd Length: 547 Bit Score: 78.12 E-value: 4.99e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 66 VDILFILGGDGTVNELINGVMSHDLQLpiGILPGGTFNDFTKTL-----NIAPNhKQASEQMISAQVGTYDVIKINNQYA 140
Cdd:PRK12361 298 ADIVIACGGDGTVTEVASELVNTDITL--GIIPLGTANALSHALfglgsKLIPV-EQACDNIIQGHTQRIDTARCNDRLM 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 141 LNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKtysgETTMILTANgpFIGGSRIPLTDLS 220
Cdd:PRK12361 375 LLLVGIGFEQKMIESADRERKNALGQLAYLDGLWRAVNENETLTLTVTLDDA----EPQTISTHS--LVVANAAPFTSLL 448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 221 PQ--------DGELN-TFI-----FNEQSFSILNDIFKkrdSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLET 286
Cdd:PRK12361 449 AQgggepnmtDGLLDiTWLdsggePGEQLLSLAELALS---GLGKEPEANKVHHAHAKKVTISSQKPIKYVIDGELFEDE 525
|
250
....*....|....*
gi 577414180 287 PIDIEVIPNAIQLLT 301
Cdd:PRK12361 526 DLTIEVQPASLKVFV 540
|
|
| PRK13054 |
PRK13054 |
lipid kinase; Reviewed |
47-299 |
1.28e-09 |
|
lipid kinase; Reviewed
Pssm-ID: 237281 [Multi-domain] Cd Length: 300 Bit Score: 57.96 E-value: 1.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 47 EGDIIKYCQEIKTKNYAKdvdiLFILGGDGTVNELINGVMSHDLQLP--IGILPGGTFNDFTKTLNIAPNHKQASEQMIS 124
Cdd:PRK13054 42 KGDAARYVEEALALGVAT----VIAGGGDGTINEVATALAQLEGDARpaLGILPLGTANDFATAAGIPLEPDKALKLAIE 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 125 AQVGTYDVIKINNQ-YALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILT 203
Cdd:PRK13054 118 GRAQPIDLARVNDRtYFINMATGGFGTRVTTETPEKLKAALGGVAYLIHGLMRMDTLKPDRCEIRGPDFHWQGDALVIGI 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 204 ANGPFIGGSRI--P-------LTDLS--PQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEItqgiehipgkkislTTDP 272
Cdd:PRK13054 198 GNGRQAGGGQQlcPealindgLLDLRilPAPQELLPTLLSTLTGGSEDNPNIIRARLPWLEI--------------QAPH 263
|
250 260
....*....|....*....|....*..
gi 577414180 273 AMKVDIDGEISLETPIDIEVIPNAIQL 299
Cdd:PRK13054 264 ELTFNLDGEPLSGRHFRIEVLPAALRC 290
|
|
| DAGKc |
smart00046 |
Diacylglycerol kinase catalytic domain (presumed); Diacylglycerol (DAG) is a second messenger ... |
62-111 |
4.36e-09 |
|
Diacylglycerol kinase catalytic domain (presumed); Diacylglycerol (DAG) is a second messenger that acts as a protein kinase C activator. DAG can be produced from the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) by a phosphoinositide-specific phospholipase C and by the degradation of phosphatidylcholine (PC) by a phospholipase C or the concerted actions of phospholipase D and phosphatidate phosphohydrolase. This domain is presumed to be the catalytic domain. Bacterial homologues areknown.
Pssm-ID: 214487 [Multi-domain] Cd Length: 124 Bit Score: 53.84 E-value: 4.36e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 577414180 62 YAKDVDI---LFILGGDGTVNELINGVMSHDLQL---PIGILPGGTFNDFTKTLNI 111
Cdd:smart00046 43 IFRDVPDfnrVLVCGGDGTVGWVLNALDKRELPLpepPVAVLPLGTGNDLARSLGW 98
|
|
| YegS_C |
pfam19279 |
YegS C-terminal NAD kinase beta sandwich-like domain; This entry represents the C-terminal ... |
164-301 |
2.15e-06 |
|
YegS C-terminal NAD kinase beta sandwich-like domain; This entry represents the C-terminal domain found in the YegS protein. It is related to the beta sandwich domain of NAD kinases. The structure of YegS reveals a two-domain protein with the active site crevice found between the two domains. The C-terminal domain contains 13 beta-strands and two alpha-helices. The likely substrate for YegS is phosphatidylglycerol.
Pssm-ID: 437111 Cd Length: 158 Bit Score: 46.81 E-value: 2.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577414180 164 FGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQS----FSIL 239
Cdd:pfam19279 22 PGALSYPAAALRALATFRPLRYRVTVDGEVREFSAALVAVANSGYYGGGMRIAPDARVDDGLLDVVVIEAASrrtlLRLL 101
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 577414180 240 NDIFK----KRDSMnwneitqgiEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLT 301
Cdd:pfam19279 102 PKVYDgrhvRLPQV---------EVLRGREVRIEADRPLPAGADGEVLGPLPVRVEVLPGALRVLA 158
|
|
| PLN02958 |
PLN02958 |
diacylglycerol kinase/D-erythro-sphingosine kinase |
47-109 |
1.51e-03 |
|
diacylglycerol kinase/D-erythro-sphingosine kinase
Pssm-ID: 215517 [Multi-domain] Cd Length: 481 Bit Score: 39.84 E-value: 1.51e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 577414180 47 EGDIIKYCQEIKTKNYAKDV---------DILFILGGDGTVNELINGVMSHD-----LQLPIGILPGGTFNDFTKTL 109
Cdd:PLN02958 141 DADIQLTIQETKYQLHAKEVvrtmdlskyDGIVCVSGDGILVEVVNGLLEREdwktaIKLPIGMVPAGTGNGMAKSL 217
|
|
| |
