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ATP-dependent helicase/deoxyribonuclease subunit B [Staphylococcus aureus M0680]
Protein Classification
helicase-exonuclease AddAB subunit AddB ( domain architecture ID 1006630 )
helicase-exonuclease AddAB subunit AddB is part of a heterodimer that acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease
List of domain hits
Name
Accession
Description
Interval
E-value
addB_Gpos super family
cl33308 helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different ...
1-1157
0e+00
helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair]
TIGR02773 :Pssm-ID: 213736 [Multi-domain]
Cd Length: 1160
Bit Score: 1370.20
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 1 M T L HAYL GR A GTGK S T KMLT EIKQK M K AD P L G D PIIL IA P T Q S TFQ L E Q A FV ND P ELNG S LR TE VL H F E RL SH R IF QE V G 80
Cdd:TIGR02773 1 M G L RFIY GR S GTGK T T FIIN EIKQK I K RN P F G K PIIL LV P D Q M TFQ M E Y A LL ND I ELNG M LR AQ VL S F S RL AW R VL QE T G 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 81 SYSEQK L SKAATE M M I YNIVQ E QQKY LK L YQ SQAKYY GF SEK L T E Q I QD FK K Y A VTPE H L EHFIADKNMQTRT K N KLED I 160
Cdd:TIGR02773 81 GLTRTF L TSTGKQ M L I RKLIE E HKDE LK V YQ KASRKK GF TAQ L S E M I TE FK R Y E VTPE D L RRMAESITDSEYL K E KLED L 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 161 AL IY RE FE Q R IQNEFITG ED S L QYFIDCM P K SE WL K R A D IYIDGFH N F STI EY LI I KG L I K Y AK S VT II LT T D GNH ---- 236
Cdd:TIGR02773 161 SI IY QQ FE E R LADQYLDS ED Y L TLLAEKI P Q SE DI K G A E IYIDGFH S F TPQ EY SV I EA L M K K AK K VT VS LT L D KPS krep 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 237 D QF SLFR KP S EVLRHIEEI A N EL N I SI E RQY F NQLY R FN - N QD L K HLE QE FD VLQINR - VAC Q GHIN I LESATM R E E INE 314
Cdd:TIGR02773 241 D EL SLFR AT S KTYYRLKQL A K EL G I DV E EPI F LNTE R PT k N KE L A HLE KQ FD ARPAIA y AEK Q ESLS I FQANNR R A E VEG 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 315 I AR R I IVDI RDK QL RY Q DIAIL Y RD - E S Y AY L FDSILPL Y N IPY N ID T KRSM TH HP VM E M IRS LIE VIQ S NW QVNPML R L 393
Cdd:TIGR02773 321 V AR E I LRLV RDK GY RY K DIAIL T RD p E D Y KD L VKAVFSD Y E IPY F ID K KRSM LN HP LI E F IRS SLD VIQ G NW RYEAVF R Y 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 394 LKT DV L TAS --- YLKSAY L V D L LEN F VL ER GI Y G - KRW LDDEL F NVEH F SKMGRKA h KL T ED E RNTF E QVVKLKKDVIDK 469
Cdd:TIGR02773 401 LKT GL L FPL nep FIDVRE L I D Q LEN Y VL AY GI K G k KRW WKEDW F QYRR F RGLDDDF - AQ T DE E IEMQ E MLNDTRDWIVPP 479
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 470 ILH FEK Q M SQ A E TVK D FA T A F YE SM E YFE LP NQ L MT ER DELDLN G NH E K A E E ID Q I W NGL IQ I LD DL V L V F G D E P M SMER 549
Cdd:TIGR02773 480 LFT FEK R M KK A K TVK E FA E A L YE FL E ELD LP DK L EK ER QRAEDD G RI E E A R E HE Q A W DAV IQ L LD EF V E V L G N E E M DLNL 559
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 550 F L EV F DIGLEQLEF VM IP QT LDQV SI GTMD LA K VD N KQHVY L V G M NDG TM P QPVTASSLIT DE EKKYF EQ QA n VELS P TS 629
Cdd:TIGR02773 560 F Q EV I DIGLEQLEF SL IP PA LDQV FV GTMD RS K MY N TKCIF L L G A NDG VL P ARPKENGILS DE DRELL EQ IG - VELS S TS 638
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 630 DILQM DE A F VC Y V A M T R A KGDVTF SY S L MGSS G DDKEI S PFLNQIQS LF NQ L EITNIPQYH E VN ---- P LS LMQHAKQ T K 705
Cdd:TIGR02773 639 REKLL DE Q F LV Y T A F T S A SDRLKV SY P L ADAE G KSLRP S IIIHRLEE LF PK L KESLLLNEP E QV sdee Q LS YVSNKLP T L 718
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 706 IT L FEA LR A W LDDEIVA D S W L D A Y QVI R DS D HLN QGL D Y LM S A L TF DNET VK L G E TLS K D LYG KE I N ASVSR F E G Y QQ CP 785
Cdd:TIGR02773 719 SE L TSQ LR K W KRGYPIS D V W W D V Y NWY R EE D KWK QGL E Y VL S G L FY DNET KQ L Q E SKA K Q LYG ER I Q ASVSR L E T Y NA CP 798
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 786 F K H Y A SH GLKL N ER TK Y E L QNF DLG DI FH SV LK Y IS ERING --- D FKQ L DLKKI R QLT N E A L E EIL PK V Q FNL L N SS AY Y 862
Cdd:TIGR02773 799 F A H F A QY GLKL K ER KI Y K L EAP DLG QL FH EA LK E IS DELKE ekl D WSD L TKEQC R LFA N D A V E NLA PK L Q HEI L L SS NR Y 878
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 863 RY LSRRIGA IV ETTLSA L KY Q GTY S K F M P KHF E TS F RRKP rtn DE L IAQT L TTTQ G IPINI RG Q IDR I D TYT K N D TSFVN 942
Cdd:TIGR02773 879 RY VQKKLKR IV TRAVGV L SE Q AKR S G F V P VGL E LG F GFGK --- NP L PPLK L QLKN G EELEL RG R IDR V D KAE K E D ETYLR 955
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 943 IIDYKSS eg S AT LDLT K VYYG MQM QM M TY M DIVL Q N KQRLGLTDI v K P G G L LYFH V H E P R I KF K SW sd ID E DKL EQ DLI K 1022
Cdd:TIGR02773 956 IIDYKSS -- S KG LDLT E VYYG LAL QM L TY L DIVL T N SAKWLGNQA - T P A G V LYFH I H D P M I QA K GD -- LT E EEI EQ EIF K 1030
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 1023 KF K LS GL VNA DQ T V IDAL D IR LE PK f T S D I V P VG L N KDGSL SK R g S QV A D E ATIYKFIQ H NKEN F I E TAS NI M DG HTEVA 1102
Cdd:TIGR02773 1031 EY K MK GL LLS DQ E V VRLM D TT LE EG - S S N I I P AS L K KDGSL GS R - S KA A T E EEFELLRK H VRRK F Q E AGE NI T DG RVSIE 1108
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|....*
gi 577246588 1103 P L K Y K QKL PC AF C SYQ SVC HV D GMIDSKR YR TVDETINPIEAIQ nin IN D E F GG E 1157
Cdd:TIGR02773 1109 P Y K M K KQT PC QY C NFS SVC QF D TSLEENE YR HLEAEKDETILEW --- IN E E V GG N 1160
Name
Accession
Description
Interval
E-value
addB_Gpos
TIGR02773 helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different ...
1-1157
0e+00
helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 213736 [Multi-domain]
Cd Length: 1160
Bit Score: 1370.20
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 1 M T L HAYL GR A GTGK S T KMLT EIKQK M K AD P L G D PIIL IA P T Q S TFQ L E Q A FV ND P ELNG S LR TE VL H F E RL SH R IF QE V G 80
Cdd:TIGR02773 1 M G L RFIY GR S GTGK T T FIIN EIKQK I K RN P F G K PIIL LV P D Q M TFQ M E Y A LL ND I ELNG M LR AQ VL S F S RL AW R VL QE T G 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 81 SYSEQK L SKAATE M M I YNIVQ E QQKY LK L YQ SQAKYY GF SEK L T E Q I QD FK K Y A VTPE H L EHFIADKNMQTRT K N KLED I 160
Cdd:TIGR02773 81 GLTRTF L TSTGKQ M L I RKLIE E HKDE LK V YQ KASRKK GF TAQ L S E M I TE FK R Y E VTPE D L RRMAESITDSEYL K E KLED L 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 161 AL IY RE FE Q R IQNEFITG ED S L QYFIDCM P K SE WL K R A D IYIDGFH N F STI EY LI I KG L I K Y AK S VT II LT T D GNH ---- 236
Cdd:TIGR02773 161 SI IY QQ FE E R LADQYLDS ED Y L TLLAEKI P Q SE DI K G A E IYIDGFH S F TPQ EY SV I EA L M K K AK K VT VS LT L D KPS krep 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 237 D QF SLFR KP S EVLRHIEEI A N EL N I SI E RQY F NQLY R FN - N QD L K HLE QE FD VLQINR - VAC Q GHIN I LESATM R E E INE 314
Cdd:TIGR02773 241 D EL SLFR AT S KTYYRLKQL A K EL G I DV E EPI F LNTE R PT k N KE L A HLE KQ FD ARPAIA y AEK Q ESLS I FQANNR R A E VEG 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 315 I AR R I IVDI RDK QL RY Q DIAIL Y RD - E S Y AY L FDSILPL Y N IPY N ID T KRSM TH HP VM E M IRS LIE VIQ S NW QVNPML R L 393
Cdd:TIGR02773 321 V AR E I LRLV RDK GY RY K DIAIL T RD p E D Y KD L VKAVFSD Y E IPY F ID K KRSM LN HP LI E F IRS SLD VIQ G NW RYEAVF R Y 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 394 LKT DV L TAS --- YLKSAY L V D L LEN F VL ER GI Y G - KRW LDDEL F NVEH F SKMGRKA h KL T ED E RNTF E QVVKLKKDVIDK 469
Cdd:TIGR02773 401 LKT GL L FPL nep FIDVRE L I D Q LEN Y VL AY GI K G k KRW WKEDW F QYRR F RGLDDDF - AQ T DE E IEMQ E MLNDTRDWIVPP 479
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 470 ILH FEK Q M SQ A E TVK D FA T A F YE SM E YFE LP NQ L MT ER DELDLN G NH E K A E E ID Q I W NGL IQ I LD DL V L V F G D E P M SMER 549
Cdd:TIGR02773 480 LFT FEK R M KK A K TVK E FA E A L YE FL E ELD LP DK L EK ER QRAEDD G RI E E A R E HE Q A W DAV IQ L LD EF V E V L G N E E M DLNL 559
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 550 F L EV F DIGLEQLEF VM IP QT LDQV SI GTMD LA K VD N KQHVY L V G M NDG TM P QPVTASSLIT DE EKKYF EQ QA n VELS P TS 629
Cdd:TIGR02773 560 F Q EV I DIGLEQLEF SL IP PA LDQV FV GTMD RS K MY N TKCIF L L G A NDG VL P ARPKENGILS DE DRELL EQ IG - VELS S TS 638
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 630 DILQM DE A F VC Y V A M T R A KGDVTF SY S L MGSS G DDKEI S PFLNQIQS LF NQ L EITNIPQYH E VN ---- P LS LMQHAKQ T K 705
Cdd:TIGR02773 639 REKLL DE Q F LV Y T A F T S A SDRLKV SY P L ADAE G KSLRP S IIIHRLEE LF PK L KESLLLNEP E QV sdee Q LS YVSNKLP T L 718
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 706 IT L FEA LR A W LDDEIVA D S W L D A Y QVI R DS D HLN QGL D Y LM S A L TF DNET VK L G E TLS K D LYG KE I N ASVSR F E G Y QQ CP 785
Cdd:TIGR02773 719 SE L TSQ LR K W KRGYPIS D V W W D V Y NWY R EE D KWK QGL E Y VL S G L FY DNET KQ L Q E SKA K Q LYG ER I Q ASVSR L E T Y NA CP 798
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 786 F K H Y A SH GLKL N ER TK Y E L QNF DLG DI FH SV LK Y IS ERING --- D FKQ L DLKKI R QLT N E A L E EIL PK V Q FNL L N SS AY Y 862
Cdd:TIGR02773 799 F A H F A QY GLKL K ER KI Y K L EAP DLG QL FH EA LK E IS DELKE ekl D WSD L TKEQC R LFA N D A V E NLA PK L Q HEI L L SS NR Y 878
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 863 RY LSRRIGA IV ETTLSA L KY Q GTY S K F M P KHF E TS F RRKP rtn DE L IAQT L TTTQ G IPINI RG Q IDR I D TYT K N D TSFVN 942
Cdd:TIGR02773 879 RY VQKKLKR IV TRAVGV L SE Q AKR S G F V P VGL E LG F GFGK --- NP L PPLK L QLKN G EELEL RG R IDR V D KAE K E D ETYLR 955
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 943 IIDYKSS eg S AT LDLT K VYYG MQM QM M TY M DIVL Q N KQRLGLTDI v K P G G L LYFH V H E P R I KF K SW sd ID E DKL EQ DLI K 1022
Cdd:TIGR02773 956 IIDYKSS -- S KG LDLT E VYYG LAL QM L TY L DIVL T N SAKWLGNQA - T P A G V LYFH I H D P M I QA K GD -- LT E EEI EQ EIF K 1030
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 1023 KF K LS GL VNA DQ T V IDAL D IR LE PK f T S D I V P VG L N KDGSL SK R g S QV A D E ATIYKFIQ H NKEN F I E TAS NI M DG HTEVA 1102
Cdd:TIGR02773 1031 EY K MK GL LLS DQ E V VRLM D TT LE EG - S S N I I P AS L K KDGSL GS R - S KA A T E EEFELLRK H VRRK F Q E AGE NI T DG RVSIE 1108
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|....*
gi 577246588 1103 P L K Y K QKL PC AF C SYQ SVC HV D GMIDSKR YR TVDETINPIEAIQ nin IN D E F GG E 1157
Cdd:TIGR02773 1109 P Y K M K KQT PC QY C NFS SVC QF D TSLEENE YR HLEAEKDETILEW --- IN E E V GG N 1160
AddB
COG3857 ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
6-1137
0e+00
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain]
Cd Length: 1019
Bit Score: 948.03
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 6 Y LGRAG T GK S T KM L T EIK QKM K A dpl G D PIIL IA P T Q S TFQ L E Q A FVNDPE L N GS L R TE VL H F E RL SH R IF QE V G SYSEQ 85
Cdd:COG3857 3 I LGRAG S GK T T YL L E EIK EEL K E --- G K PIIL LV P E Q M TFQ A E R A LLKRLG L G GS I R AQ VL S F S RL AW R VL QE T G GATRP 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 86 K LS K A ATE M MIYN I VQ E QQKY LK LYQSQ A KYY GF S E K L T E Q I QDF K K Y AV TPE H LE HFIA dknmqt RT K N KL E D I ALIY R 165
Cdd:COG3857 80 L LS D A GKR M LLRK I LE E HKDE LK VFARA A DKP GF I E Q L A E L I TEL K R Y GI TPE D LE EAAE ------ LL K E KL R D L ALIY E 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 166 EF E QRIQNEF I TG ED S L QYFIDCMP KSE W L KR A D IYIDGF HN F STI E YLIIKG L I K Y AK S VTI I LT T D gn H D QFS LF RKP 245
Cdd:COG3857 154 AY E EKLAGRY I DS ED L L RLLAEKLE KSE F L EG A E IYIDGF TD F TPQ E LELLEA L L K K AK E VTI T LT L D -- P D ELD LF SAT 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 246 S E VLRHIE E I A N E LNISI E RQ yfnqlyrf NNQD L K HLE QEFDVLQINRVA cq GH I N I L E S A TM R E E INEI AR R I IVDI R D 325
Cdd:COG3857 232 G E TYERLL E L A K E NGVEV E FK -------- KSPE L A HLE RNLFAYPPEEEP -- EG I E I I E A A NR R A E VEAV AR E I RRLV R E 301
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 326 KQL RY Q DIA ILY RD - E S YA Y L FDSILPL Y N IPY N ID T KR SMT HHP VM E M I R SL I E VIQ SN WQVNPML RLLKT DV L TA syl 404
Cdd:COG3857 302 EGY RY R DIA VVV RD l E A YA P L IERVFAE Y G IPY F ID E KR PLS HHP LV E L I L SL L E LVR SN FRYEDVF RLLKT GL L RP --- 378
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 405 K S AYLV D L LEN F VL ER GI Y G K RWL DDE L F nvehfskmgr KAHK LT ED E RNTF E QVVK L KKDVIDKI L HFEKQMSQ A E TV K 484
Cdd:COG3857 379 L S REEI D R LEN Y VL AY GI R G R RWL ERY L E ---------- EEEE LT DE E EEDL E RLNE L RDRLLEPL L PLRERLKK A K TV R 448
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 485 DF A T A F YE SM E YFEL P NQ L MTE R d E LDLN G NH E K A E E ID Q I WN G LI QI LD D LV L V F GDE PM S M E R FL EVFDI GLE Q L E F V 564
Cdd:COG3857 449 EW A E A L YE FL E ELGV P EK L EEW R - E AEEA G DL E E A R E HE Q A WN A LI EL LD E LV E V L GDE KL S L E E FL RILES GLE E L T F G 527
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 565 M IP QT LDQV SI G TM D L A KVDNKQH V YLV G M N D G TM P QPVTASS L IT DEE KKYF e QQANV EL S PTS DILQMD E A F VC Y V A M 644
Cdd:COG3857 528 L IP PS LDQV QV G GL D R A RGLDFKA V FVL G L N E G VF P ARPREDG L LS DEE RERL - NELGL EL P PTS RERLLE E R F LF Y R A L 606
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 645 TRA KGDVTF SY S L MGSS G DDKEI SP FLNQIQS LF NQ LE ITNIPQ yhev NP L SLMQHAKQT kitl FEA L R A W L DDEIV A DS 724
Cdd:COG3857 607 TRA SERLYL SY P L ADEE G KALLP SP LIDRLRE LF PE LE ERSLLE ---- EE L EYIGTPESA ---- LSE L A A A L RQLEL A PL 678
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 725 W L D A Y QVI rdsdhlnqgldylmsaltfdnetvklgetlskdlygke INA SVSR F E G Y QQ CPF KHYASH GLKL N ER TK YEL 804
Cdd:COG3857 679 W W D V Y KWL -------------------------------------- LKL SVSR L E T Y AA CPF QFFLRY GLKL K ER EE YEL 720
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 805 QNF D L G DI FH S VL KYISERI --- NG D FKQ L DLKKIRQ L TN EA L EE IL P KV Q FNL L N SSA Y YRYL SR R IGAIVETTLSA L K 881
Cdd:COG3857 721 DAP D R G TL FH A VL ERFYKEL kee GL D WAD L SDEELEE L LE EA V EE LA P EL Q NGI L L SSA R YRYL LE R LKRLLKRARRW L E 800
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 882 YQGTY S K F M P KHF E T SF RR kprt NDE L IAQT L TTTQ G IP I NI RG Q IDRID TYTKND t SFVN IIDYKS se GS ATL DL TK VY 961
Cdd:COG3857 801 EEARR S G F E P VAL E L SF GP ---- EGG L PPLE L ELPN G RK I RL RG R IDRID RLESDG - RYLR IIDYKS -- GS KKF DL DD VY 873
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 962 YG MQM Q MMT Y M D IV L Q N KQ rlgl TDIVK P G G L LYFH VHE P RI K F K SW sdidedkleqdl I KK F K LS GL VNA D QT V I dald 1041
Cdd:COG3857 874 YG LAL Q LPL Y L D AA L E N LE ---- GKEAE P A G A LYFH LKN P KL K A K KP ------------ L KK L K MK GL LLD D PE V L ---- 933
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 1042 irlepkfts D I V P vg L N KDGS LSK rg S Q V AD E ATIYKFIQ H NK E NFI E TASN I MD G HTEVA P LKY K QKLP C AF C S Y Q S V C 1121
Cdd:COG3857 934 --------- E I I P -- L K KDGS FKN -- S K V LS E EEFEELLD H VR E LLK E AGEE I LA G DFAIN P YRT K DRTA C QY C P Y K S I C 1000
1130
....*....|....*.
gi 577246588 1122 HV D GMIDSKR YR TVDE 1137
Cdd:COG3857 1001 RF D ESLEGNE YR KLKK 1016
PDDEXK_1
pfam12705 PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease ...
774-1122
9.45e-29
PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease superfamily
Pssm-ID: 432731 [Multi-domain]
Cd Length: 250
Bit Score: 116.09
E-value: 9.45e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 774 S V SR F E G Y QQ CP FKHYASHG L K L ne R TKY EL QNF DLG DIF H SV L KYISE ringd FKQ L DLKKIRQ L TNEA LEE IL P KV q F 853
Cdd:pfam12705 3 S P SR L E T Y LT CP LRFFLRYL L G L -- R EDE EL DAP DLG TLV H AA L ERFYR ----- WGR L PEEDLEE L LQAL LEE LW P EL - G 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 854 NLLNSSAYYRY L SR R IGAIV E TT L SA L KYQGTYS - K F M P KHF E TS F rrkprtndeliaqtlttt Q G IPINIR G Q IDR I D t 932
Cdd:pfam12705 75 LQSEILPRLPW L AG R LRRRL E RM L RR L AEWLRAR r G F R P VAV E LG F ------------------ G G TTVRLV G R IDR V D - 135
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 933 y TKNDTSFV n IIDYK SSEGSATLDLTKV Y Y G mq M Q MMT Y MDIVLQNKQR LG ltdiv K P G G L LY FHVHE P RI K fkswsdi D 1012
Cdd:pfam12705 136 - LDGEGYLR - IIDYK TGSAPPQSEDLDL Y E G -- L Q LLL Y LLALAAGEKA LG ----- G P A G A LY LRLDD P LK K ------- D 199
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 1013 E DKL E Q dlikkfklsglvnadqtvidaldirlepkftsdivpvglnkdgslskrgs Q V AD E ATIYKFI Q H nken FI E T A S 1092
Cdd:pfam12705 200 E EVV E P -------------------------------------------------- M V LT E DEFDALL Q E ---- LR E L A E 225
330 340 350
....*....|....*....|....*....|
gi 577246588 1093 N I MD G HTEVA P L K Y kqklp C AF C S Y Q S V C H 1122
Cdd:pfam12705 226 E I LA G EFPAR P G K K ----- C RY C P Y R S I C P 250
PRK10919
PRK10919 ATP-dependent DNA helicase Rep; Provisional
326-654
6.09e-04
ATP-dependent DNA helicase Rep; Provisional
Pssm-ID: 182838 [Multi-domain]
Cd Length: 672
Bit Score: 44.06
E-value: 6.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 326 KQLR Y Q D I AILYR DESYAYL F DSI L PLYN IPY N I DTKR S MTHH P VMEMIRSLIE V IQSNWQVNPM LR LLK T dvl TASYLK 405
Cdd:PRK10919 338 NKTQ Y K D Y AILYR GNHQSRV F EKF L MQNR IPY K I SGGT S FFSR P EIKDLLAYLR V LTNPDDDSAF LR IVN T --- PKREIG 414
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 406 S A Y L VD L L E n FVLE R giygkrwl DDE LF NV ------- EHF S KM G ----- R KA H K L T E DE R NTFEQV V KLKK D V I DK I lhf 473
Cdd:PRK10919 415 P A T L QK L G E - WAMT R -------- NKS LF TA sfdmgls QTL S GR G yeslt R FT H W L A E IQ R LAEREP V AAVR D L I HG I --- 482
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 474 ekqmsqaetvk D fataf YES ME Y FEL P NQLMT E R deldlngnhe KAEEID Q IWNGLIQI L -- DD L vlvfg DEPM SMERFL 551
Cdd:PRK10919 483 ----------- D ----- YES WL Y ETS P SPKAA E M ---------- RMKNVN Q LFSWMTEM L eg SE L ----- DEPM TLTQVV 531
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 552 EV F DI g LEQL E FVMIPQT LDQV SIG T MDLA K VDNKQH VYLVGM ND G TM P Q pvt A SS L it DE E kkyfeqqa N VE lsptsdi 631
Cdd:PRK10919 532 TR F TL - RDMM E RGESEEE LDQV QLM T LHAS K GLEFPY VYLVGM EE G LL P H --- Q SS I -- DE D -------- N ID ------- 590
330 340
....*....|....*....|...
gi 577246588 632 lqm D E AFVC YV AM TRA KGDV TF S 654
Cdd:PRK10919 591 --- E E RRLA YV GI TRA QKEL TF T 610
Name
Accession
Description
Interval
E-value
addB_Gpos
TIGR02773 helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different ...
1-1157
0e+00
helicase-exonuclease AddAB, AddB subunit; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 213736 [Multi-domain]
Cd Length: 1160
Bit Score: 1370.20
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 1 M T L HAYL GR A GTGK S T KMLT EIKQK M K AD P L G D PIIL IA P T Q S TFQ L E Q A FV ND P ELNG S LR TE VL H F E RL SH R IF QE V G 80
Cdd:TIGR02773 1 M G L RFIY GR S GTGK T T FIIN EIKQK I K RN P F G K PIIL LV P D Q M TFQ M E Y A LL ND I ELNG M LR AQ VL S F S RL AW R VL QE T G 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 81 SYSEQK L SKAATE M M I YNIVQ E QQKY LK L YQ SQAKYY GF SEK L T E Q I QD FK K Y A VTPE H L EHFIADKNMQTRT K N KLED I 160
Cdd:TIGR02773 81 GLTRTF L TSTGKQ M L I RKLIE E HKDE LK V YQ KASRKK GF TAQ L S E M I TE FK R Y E VTPE D L RRMAESITDSEYL K E KLED L 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 161 AL IY RE FE Q R IQNEFITG ED S L QYFIDCM P K SE WL K R A D IYIDGFH N F STI EY LI I KG L I K Y AK S VT II LT T D GNH ---- 236
Cdd:TIGR02773 161 SI IY QQ FE E R LADQYLDS ED Y L TLLAEKI P Q SE DI K G A E IYIDGFH S F TPQ EY SV I EA L M K K AK K VT VS LT L D KPS krep 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 237 D QF SLFR KP S EVLRHIEEI A N EL N I SI E RQY F NQLY R FN - N QD L K HLE QE FD VLQINR - VAC Q GHIN I LESATM R E E INE 314
Cdd:TIGR02773 241 D EL SLFR AT S KTYYRLKQL A K EL G I DV E EPI F LNTE R PT k N KE L A HLE KQ FD ARPAIA y AEK Q ESLS I FQANNR R A E VEG 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 315 I AR R I IVDI RDK QL RY Q DIAIL Y RD - E S Y AY L FDSILPL Y N IPY N ID T KRSM TH HP VM E M IRS LIE VIQ S NW QVNPML R L 393
Cdd:TIGR02773 321 V AR E I LRLV RDK GY RY K DIAIL T RD p E D Y KD L VKAVFSD Y E IPY F ID K KRSM LN HP LI E F IRS SLD VIQ G NW RYEAVF R Y 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 394 LKT DV L TAS --- YLKSAY L V D L LEN F VL ER GI Y G - KRW LDDEL F NVEH F SKMGRKA h KL T ED E RNTF E QVVKLKKDVIDK 469
Cdd:TIGR02773 401 LKT GL L FPL nep FIDVRE L I D Q LEN Y VL AY GI K G k KRW WKEDW F QYRR F RGLDDDF - AQ T DE E IEMQ E MLNDTRDWIVPP 479
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 470 ILH FEK Q M SQ A E TVK D FA T A F YE SM E YFE LP NQ L MT ER DELDLN G NH E K A E E ID Q I W NGL IQ I LD DL V L V F G D E P M SMER 549
Cdd:TIGR02773 480 LFT FEK R M KK A K TVK E FA E A L YE FL E ELD LP DK L EK ER QRAEDD G RI E E A R E HE Q A W DAV IQ L LD EF V E V L G N E E M DLNL 559
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 550 F L EV F DIGLEQLEF VM IP QT LDQV SI GTMD LA K VD N KQHVY L V G M NDG TM P QPVTASSLIT DE EKKYF EQ QA n VELS P TS 629
Cdd:TIGR02773 560 F Q EV I DIGLEQLEF SL IP PA LDQV FV GTMD RS K MY N TKCIF L L G A NDG VL P ARPKENGILS DE DRELL EQ IG - VELS S TS 638
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 630 DILQM DE A F VC Y V A M T R A KGDVTF SY S L MGSS G DDKEI S PFLNQIQS LF NQ L EITNIPQYH E VN ---- P LS LMQHAKQ T K 705
Cdd:TIGR02773 639 REKLL DE Q F LV Y T A F T S A SDRLKV SY P L ADAE G KSLRP S IIIHRLEE LF PK L KESLLLNEP E QV sdee Q LS YVSNKLP T L 718
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 706 IT L FEA LR A W LDDEIVA D S W L D A Y QVI R DS D HLN QGL D Y LM S A L TF DNET VK L G E TLS K D LYG KE I N ASVSR F E G Y QQ CP 785
Cdd:TIGR02773 719 SE L TSQ LR K W KRGYPIS D V W W D V Y NWY R EE D KWK QGL E Y VL S G L FY DNET KQ L Q E SKA K Q LYG ER I Q ASVSR L E T Y NA CP 798
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 786 F K H Y A SH GLKL N ER TK Y E L QNF DLG DI FH SV LK Y IS ERING --- D FKQ L DLKKI R QLT N E A L E EIL PK V Q FNL L N SS AY Y 862
Cdd:TIGR02773 799 F A H F A QY GLKL K ER KI Y K L EAP DLG QL FH EA LK E IS DELKE ekl D WSD L TKEQC R LFA N D A V E NLA PK L Q HEI L L SS NR Y 878
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 863 RY LSRRIGA IV ETTLSA L KY Q GTY S K F M P KHF E TS F RRKP rtn DE L IAQT L TTTQ G IPINI RG Q IDR I D TYT K N D TSFVN 942
Cdd:TIGR02773 879 RY VQKKLKR IV TRAVGV L SE Q AKR S G F V P VGL E LG F GFGK --- NP L PPLK L QLKN G EELEL RG R IDR V D KAE K E D ETYLR 955
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 943 IIDYKSS eg S AT LDLT K VYYG MQM QM M TY M DIVL Q N KQRLGLTDI v K P G G L LYFH V H E P R I KF K SW sd ID E DKL EQ DLI K 1022
Cdd:TIGR02773 956 IIDYKSS -- S KG LDLT E VYYG LAL QM L TY L DIVL T N SAKWLGNQA - T P A G V LYFH I H D P M I QA K GD -- LT E EEI EQ EIF K 1030
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 1023 KF K LS GL VNA DQ T V IDAL D IR LE PK f T S D I V P VG L N KDGSL SK R g S QV A D E ATIYKFIQ H NKEN F I E TAS NI M DG HTEVA 1102
Cdd:TIGR02773 1031 EY K MK GL LLS DQ E V VRLM D TT LE EG - S S N I I P AS L K KDGSL GS R - S KA A T E EEFELLRK H VRRK F Q E AGE NI T DG RVSIE 1108
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|....*
gi 577246588 1103 P L K Y K QKL PC AF C SYQ SVC HV D GMIDSKR YR TVDETINPIEAIQ nin IN D E F GG E 1157
Cdd:TIGR02773 1109 P Y K M K KQT PC QY C NFS SVC QF D TSLEENE YR HLEAEKDETILEW --- IN E E V GG N 1160
AddB
COG3857 ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
6-1137
0e+00
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain]
Cd Length: 1019
Bit Score: 948.03
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 6 Y LGRAG T GK S T KM L T EIK QKM K A dpl G D PIIL IA P T Q S TFQ L E Q A FVNDPE L N GS L R TE VL H F E RL SH R IF QE V G SYSEQ 85
Cdd:COG3857 3 I LGRAG S GK T T YL L E EIK EEL K E --- G K PIIL LV P E Q M TFQ A E R A LLKRLG L G GS I R AQ VL S F S RL AW R VL QE T G GATRP 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 86 K LS K A ATE M MIYN I VQ E QQKY LK LYQSQ A KYY GF S E K L T E Q I QDF K K Y AV TPE H LE HFIA dknmqt RT K N KL E D I ALIY R 165
Cdd:COG3857 80 L LS D A GKR M LLRK I LE E HKDE LK VFARA A DKP GF I E Q L A E L I TEL K R Y GI TPE D LE EAAE ------ LL K E KL R D L ALIY E 153
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 166 EF E QRIQNEF I TG ED S L QYFIDCMP KSE W L KR A D IYIDGF HN F STI E YLIIKG L I K Y AK S VTI I LT T D gn H D QFS LF RKP 245
Cdd:COG3857 154 AY E EKLAGRY I DS ED L L RLLAEKLE KSE F L EG A E IYIDGF TD F TPQ E LELLEA L L K K AK E VTI T LT L D -- P D ELD LF SAT 231
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 246 S E VLRHIE E I A N E LNISI E RQ yfnqlyrf NNQD L K HLE QEFDVLQINRVA cq GH I N I L E S A TM R E E INEI AR R I IVDI R D 325
Cdd:COG3857 232 G E TYERLL E L A K E NGVEV E FK -------- KSPE L A HLE RNLFAYPPEEEP -- EG I E I I E A A NR R A E VEAV AR E I RRLV R E 301
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 326 KQL RY Q DIA ILY RD - E S YA Y L FDSILPL Y N IPY N ID T KR SMT HHP VM E M I R SL I E VIQ SN WQVNPML RLLKT DV L TA syl 404
Cdd:COG3857 302 EGY RY R DIA VVV RD l E A YA P L IERVFAE Y G IPY F ID E KR PLS HHP LV E L I L SL L E LVR SN FRYEDVF RLLKT GL L RP --- 378
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 405 K S AYLV D L LEN F VL ER GI Y G K RWL DDE L F nvehfskmgr KAHK LT ED E RNTF E QVVK L KKDVIDKI L HFEKQMSQ A E TV K 484
Cdd:COG3857 379 L S REEI D R LEN Y VL AY GI R G R RWL ERY L E ---------- EEEE LT DE E EEDL E RLNE L RDRLLEPL L PLRERLKK A K TV R 448
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 485 DF A T A F YE SM E YFEL P NQ L MTE R d E LDLN G NH E K A E E ID Q I WN G LI QI LD D LV L V F GDE PM S M E R FL EVFDI GLE Q L E F V 564
Cdd:COG3857 449 EW A E A L YE FL E ELGV P EK L EEW R - E AEEA G DL E E A R E HE Q A WN A LI EL LD E LV E V L GDE KL S L E E FL RILES GLE E L T F G 527
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 565 M IP QT LDQV SI G TM D L A KVDNKQH V YLV G M N D G TM P QPVTASS L IT DEE KKYF e QQANV EL S PTS DILQMD E A F VC Y V A M 644
Cdd:COG3857 528 L IP PS LDQV QV G GL D R A RGLDFKA V FVL G L N E G VF P ARPREDG L LS DEE RERL - NELGL EL P PTS RERLLE E R F LF Y R A L 606
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 645 TRA KGDVTF SY S L MGSS G DDKEI SP FLNQIQS LF NQ LE ITNIPQ yhev NP L SLMQHAKQT kitl FEA L R A W L DDEIV A DS 724
Cdd:COG3857 607 TRA SERLYL SY P L ADEE G KALLP SP LIDRLRE LF PE LE ERSLLE ---- EE L EYIGTPESA ---- LSE L A A A L RQLEL A PL 678
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 725 W L D A Y QVI rdsdhlnqgldylmsaltfdnetvklgetlskdlygke INA SVSR F E G Y QQ CPF KHYASH GLKL N ER TK YEL 804
Cdd:COG3857 679 W W D V Y KWL -------------------------------------- LKL SVSR L E T Y AA CPF QFFLRY GLKL K ER EE YEL 720
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 805 QNF D L G DI FH S VL KYISERI --- NG D FKQ L DLKKIRQ L TN EA L EE IL P KV Q FNL L N SSA Y YRYL SR R IGAIVETTLSA L K 881
Cdd:COG3857 721 DAP D R G TL FH A VL ERFYKEL kee GL D WAD L SDEELEE L LE EA V EE LA P EL Q NGI L L SSA R YRYL LE R LKRLLKRARRW L E 800
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 882 YQGTY S K F M P KHF E T SF RR kprt NDE L IAQT L TTTQ G IP I NI RG Q IDRID TYTKND t SFVN IIDYKS se GS ATL DL TK VY 961
Cdd:COG3857 801 EEARR S G F E P VAL E L SF GP ---- EGG L PPLE L ELPN G RK I RL RG R IDRID RLESDG - RYLR IIDYKS -- GS KKF DL DD VY 873
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 962 YG MQM Q MMT Y M D IV L Q N KQ rlgl TDIVK P G G L LYFH VHE P RI K F K SW sdidedkleqdl I KK F K LS GL VNA D QT V I dald 1041
Cdd:COG3857 874 YG LAL Q LPL Y L D AA L E N LE ---- GKEAE P A G A LYFH LKN P KL K A K KP ------------ L KK L K MK GL LLD D PE V L ---- 933
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 1042 irlepkfts D I V P vg L N KDGS LSK rg S Q V AD E ATIYKFIQ H NK E NFI E TASN I MD G HTEVA P LKY K QKLP C AF C S Y Q S V C 1121
Cdd:COG3857 934 --------- E I I P -- L K KDGS FKN -- S K V LS E EEFEELLD H VR E LLK E AGEE I LA G DFAIN P YRT K DRTA C QY C P Y K S I C 1000
1130
....*....|....*.
gi 577246588 1122 HV D GMIDSKR YR TVDE 1137
Cdd:COG3857 1001 RF D ESLEGNE YR KLKK 1016
rexB_recomb
TIGR02774 ATP-dependent nuclease subunit B; DNA repair is accomplished by several different systems in ...
19-1034
1.69e-39
ATP-dependent nuclease subunit B; DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RecAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. The partner may be designated AddB, as in Bacillus and in alphaproteobacteria, or RexB as in Streptococcus and Lactococcus. Note, however, that RexB proteins lack an N-terminal GxxGxGK[ST] ATP-binding motif found in Bacillus subtilis and related species, and this difference may be important; this model represents specifically RexB proteins as found in Streptococcus and Lactococcus. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274291 [Multi-domain]
Cd Length: 1076
Bit Score: 159.61
E-value: 1.69e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 19 LTEI -- KQKMK A DPL G DPIIL IAP TQST F QL E Q A FVNDPELNG S LRTE V LH F ERLS h R I F QEVGSYSEQK L SKAATE M MI 96
Cdd:TIGR02774 11 LTEI lv NEAEE A AAA G KRVFY IAP NSLS F EK E R A VLEYLPQQA S FSIT V TR F AQMA - R Y F VLNDLPAKTT L DDIGLA M IF 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 97 Y NIVQE - QQKY LK L Y QSQAKYYG F SEK L T E QIQDFK K YAVTPEH LE HFIADK nmqtrtkn K L ED IAL I YREFEQRIQNEF 175
Cdd:TIGR02774 90 Y RALAQ l EPGD LK V Y GRLKQDPQ F IQQ L V E LYKELQ K SQLSILD LE NLTSPD -------- K R ED LLA I FEKVTAYLNQGQ 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 176 ITGEDS L QY FI DCMPKSEW --- LK RADIY IDGF HN FS TI E YLIIKG L ik YA K S V T II LTT ------------ D GN ----- 235
Cdd:TIGR02774 162 YAQQSK L AH FI EAIESGKL dsd LK NTVLV IDGF TR FS AE E EALVSL L -- HG K G V E II IGA yasqkaykssfs E GN lyqas 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 236 ---- HD QFSLFRKPS E VLRHIE E IAN el NISIERQYFNQLYR F NNQD L KHLEQEF D vlqinrvacqg HIN I LESA T MR EE 311
Cdd:TIGR02774 240 vkfl HD LAQKYQTKA E FISSTH E SKD -- SFDKLSRLLEASHD F SELA L DLDDKDK D ----------- NLT I WSCL T QK EE 306
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 312 INEI AR R I IVDIRDK q L RY Q DI AI L YR D - E SY AYLFDS I LPL Y N IP YNIDTKRS M T HHP VMEM I R SL IEVIQSNWQVNPM 390
Cdd:TIGR02774 307 VEHV AR S I RQKLYEG - Y RY K DI LV L LG D v D SY QLQLGK I FDQ Y D IP FYLGKAEP M A HHP LVQF I E SL ERIKRYRFRAEDV 385
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 391 L R LLKT DVLTAS ylk S AYLV D LL E NFVLERG I Y G KRWLDDEL ------- F NVEHFSKMGR kah KLTEDERNT F EQVVK L K 463
Cdd:TIGR02774 386 L N LLKT GLYGDF --- S QSDI D AF E QYIRYAD I K G LPKFQKTF tknhhgk F DLDRLNVLRQ --- RILAPLEEL F KSRKQ L G 459
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 464 KDVID K ILH F E K QMSQAETVK D F AT afye SMEYF E L pnqlmterdeldlngnh EK A EE idq I W NGLIQ IL DDLVLV FG D E 543
Cdd:TIGR02774 460 EKLLN K FSV F L K EIALTKNLQ D L AT ---- TLSEV E Q ----------------- EK Q EE --- V W KTFTD IL EQFATI FG Q E 515
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 544 PM S MER FL EVFDI G LEQLEFVMI P Q T L D Q V SIGTM DL AKVDNKQH VY LV G MNDGTM P QPVTA SSL I TDEE KKYFEQQANV 623
Cdd:TIGR02774 516 KL S LDD FL ALLHS G MSLSQYRTV P A T V D V V TVKSY DL IEPHTAPF VY AI G LTQSNF P KISQN SSL L TDEE RQNLNDATEE 595
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 624 E --- LSPTSDI L QMDE a FVCYVAMTR A KGDVTF S YSLMGSSGD DKE i SP F L NQIQSL ---------- FNQLEITN I PQ Y H 690
Cdd:TIGR02774 596 G ghf DIASQEN L KKNH - YTMLSLFNS A TKELVL S APQLFNESE DKE - SP Y L QELIDF gvplrekgmn SLGEDKED I GN Y K 673
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 691 ------- EV N PLSL M QHA KQ TKI --- T L FEA LR AW LD deivadswldayqvirdsdhl N QGL D yl MSAL T FDNE T VK L GE 760
Cdd:TIGR02774 674 allsrvv AY N QQGE M EMT KQ DLT fws V L VRY LR KK LD --------------------- Q QGL E -- IPTI T DSLS T KT L SK 730
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 761 TLSKD LY -- GKEINA S V S RFEGYQQCPFKHYASHG L K L N E RTKYELQNFDL G DIF H SVL kyis ER I ngd F K QLDLKKIR Q 838
Cdd:TIGR02774 731 DVLQA LY pa DQPLKL S A S ALTTFYNNQYSYFLRYV L G L E E EESIHPDARHH G NYL H RIF ---- ER L --- M K LPGEESFD Q 803
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 839 LT N E A LE E ILPKVQ F NL L NS - S A YY RY LSRRIGA I VET T LSA L KY - QGTYSKFMPKH F ETSFRRK prtndeliaqt L TTT 916
Cdd:TIGR02774 804 KL N Q A IN E TSQERE F EA L YQ e D A EA RY TLEILLD I ARS T API L RH n SAIQVIKEEEN F GGKDNFQ ----------- L QID 872
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 917 Q G IP I NI RG Q IDRID TYTKNDT sf VNII DYKSS eg SATL D LTKV Y Y G MQM Q MM TY MDIVLQNKQRL G LTD I V kpg G LL Y F 996
Cdd:TIGR02774 873 N G RS I FV RG I IDRID RLSDGGS -- LGVV DYKSS -- ATQF D IPHF Y N G LSP Q LP TY LAALKRIAPHE G EQP I F --- G AM Y L 945
1050 1060 1070
....*....|....*....|....*....|....*...
gi 577246588 997 H VH EP RIKFKSWSDI D E dk LEQDLI K KF K LS GL VNADQ 1034
Cdd:TIGR02774 946 H MQ EP VQDLMAVKNL D D -- AVVEAS K AL K YQ GL FSEKE 981
PDDEXK_1
pfam12705 PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease ...
774-1122
9.45e-29
PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease superfamily
Pssm-ID: 432731 [Multi-domain]
Cd Length: 250
Bit Score: 116.09
E-value: 9.45e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 774 S V SR F E G Y QQ CP FKHYASHG L K L ne R TKY EL QNF DLG DIF H SV L KYISE ringd FKQ L DLKKIRQ L TNEA LEE IL P KV q F 853
Cdd:pfam12705 3 S P SR L E T Y LT CP LRFFLRYL L G L -- R EDE EL DAP DLG TLV H AA L ERFYR ----- WGR L PEEDLEE L LQAL LEE LW P EL - G 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 854 NLLNSSAYYRY L SR R IGAIV E TT L SA L KYQGTYS - K F M P KHF E TS F rrkprtndeliaqtlttt Q G IPINIR G Q IDR I D t 932
Cdd:pfam12705 75 LQSEILPRLPW L AG R LRRRL E RM L RR L AEWLRAR r G F R P VAV E LG F ------------------ G G TTVRLV G R IDR V D - 135
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 933 y TKNDTSFV n IIDYK SSEGSATLDLTKV Y Y G mq M Q MMT Y MDIVLQNKQR LG ltdiv K P G G L LY FHVHE P RI K fkswsdi D 1012
Cdd:pfam12705 136 - LDGEGYLR - IIDYK TGSAPPQSEDLDL Y E G -- L Q LLL Y LLALAAGEKA LG ----- G P A G A LY LRLDD P LK K ------- D 199
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 1013 E DKL E Q dlikkfklsglvnadqtvidaldirlepkftsdivpvglnkdgslskrgs Q V AD E ATIYKFI Q H nken FI E T A S 1092
Cdd:pfam12705 200 E EVV E P -------------------------------------------------- M V LT E DEFDALL Q E ---- LR E L A E 225
330 340 350
....*....|....*....|....*....|
gi 577246588 1093 N I MD G HTEVA P L K Y kqklp C AF C S Y Q S V C H 1122
Cdd:pfam12705 226 E I LA G EFPAR P G K K ----- C RY C P Y R S I C P 250
UvrD
COG0210 Superfamily I DNA or RNA helicase [Replication, recombination and repair];
300-674
1.15e-11
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
Pssm-ID: 439980 [Multi-domain]
Cd Length: 721
Bit Score: 69.19
E-value: 1.15e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 300 INILESATMR EE INEI A RR I I v DIRDKQLRYQ DIA I LYR DESYAYLFDSI L PLYN IPY NIDTKRSMTHHPVMEMIRSLIE 379
Cdd:COG0210 317 VRLYVAPDEE EE ARFV A DE I R - ELHEEGVPLS DIA V LYR TNAQSRALEEA L RRAG IPY RVVGGLRFYERAEIKDLLAYLR 395
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 380 VI qsnwq V NP ----- M LR L L KT dvl TASYLKS A Y L v DL L ENFVL E R GI YGKRW L D D ELF nvehfskmgrk AHK L TEDERN 454
Cdd:COG0210 396 LL ----- A NP dddva L LR I L NV --- PRRGIGA A T L - ER L REAAR E E GI SLLEA L R D LGE ----------- LAG L SGRAAK 455
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 455 TFEQVVK L kkdv IDKI lhfe KQMSQAETVKDFAT A FYESME Y F E LPNQLMT E RD E ldlngnh EKA E EIDQ iwng L IQILD 534
Cdd:COG0210 456 ALRRFAE L ---- LEAL ---- RAAAERLPLEELLE A LLDESG Y E E ELREEAG E EA E ------- RRL E NLEE ---- L VDAAA 516
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 535 DLVL vf GDEPM S M E R FLE VFDIGLEQLE fvm IPQTL D Q V SIG T MDL AK --- VD nkq H V Y LVG MND G TM P qpv TAS SL ITD 611
Cdd:COG0210 517 RFEE -- RNPGA S L E A FLE ELALLSDLDA --- ADEDE D A V TLM T LHA AK gle FP --- V V F LVG LEE G LF P --- HQR SL DDE 585
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 577246588 612 EE kkyfeqqanvelsptsdilq MD E AF - VC YVA M TRA KGDVTFS Y SLMGS --- SGD D K E I S P FL NQI 674
Cdd:COG0210 586 EE -------------------- LE E ER r LF YVA I TRA RERLYLT Y AASRR lwg ETQ D N E P S R FL DEL 632
Slr0479
COG2887 RecB family exonuclease [Replication, recombination and repair];
774-949
1.29e-11
RecB family exonuclease [Replication, recombination and repair];
Pssm-ID: 442133 [Multi-domain]
Cd Length: 248
Bit Score: 66.21
E-value: 1.29e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 774 S V SR F E GYQQ CP FKH YA SHG L K L NERTKYELQNF D L G DIF H S VL KYISERINGD fkq L DLKKIRQ L TN EA LE E ILPK vqf 853
Cdd:COG2887 4 S P SR I E TLLR CP LRY YA RYI L G L RDPLEPPPDAA D R G TLV H A VL ERFYKLPADE --- L PAEELLA L LE EA WA E LGFE --- 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 854 nlln SSAYYRYLSR R IGAIV E T tls A L KYQGTYSKFM P KHF E TS F R rkprtndeliaqt L TTTQ G IP in I RG Q IDRID ty 933
Cdd:COG2887 78 ---- DPWAAALWLE R AERLL E A --- F L EWERAPAGLE P VAV E VE F E ------------- L ELPG G VR -- L RG R IDRID -- 133
170
....*....|....*.
gi 577246588 934 t KNDTSFVNII DYK SS 949
Cdd:COG2887 134 - RLPDGRLVVV DYK TG 148
UvrD_C
pfam13361 UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ...
300-656
1.46e-06
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 433145 [Multi-domain]
Cd Length: 377
Bit Score: 52.02
E-value: 1.46e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 300 I N I L E SA T MR EE INE IA RR I I v DIRDKQLR Y Q DIA I L Y R DE S Y A Y L FDSI L PLYN IPY N - IDTKRSMTHHPVMEMI r SLI 378
Cdd:pfam13361 46 I K I I E AE T EE EE AEW IA LE I K - KLVARDEK Y N DIA V L T R SN S D A D L IEEA L KKLG IPY F v VGQTKFFRREEIKDIL - AYL 123
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 379 EV I QSNWQVNPML R L L KT ---------- DVLTASYLKSAY L V D LLENFV L ER G IYGKRW L DDE --- L F N VE hfskmg RKA 445
Cdd:pfam13361 124 RL I ANKHDSISLK R I L NG pkrgignatl ERIREYKKRGLR L S D FINPDT L TY G DPFVIA L EQD niv V F D VE ------ TTG 197
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 446 HKL TEDE rnt FE Q VVKL K ---- KD VI DK ilh FE KQMSQAET V K D fatafyesm EYFELPNQLMTERDEL dlngn HEK AE E 521
Cdd:pfam13361 198 LDT TEDE --- II Q IAAI K lnkk GV VI ES --- FE RFLRLKKP V G D --------- SLQVHGFSDEFLQENG ----- ETP AE A 257
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 522 IDQIWN g LIQI L DD L VLVF ----- GD E PMSM E R ---- FLE VFDIGLEQ LE FVM I pqt LDQVS I G T MDL AK --- V D N kqh V 589
Cdd:pfam13361 258 LRDFLE - KLEN L RE L YSIL reydd IE E TPEP E D alrn FLE IATLSNSE LE GSD I --- KERIP I M T IHQ AK gle F D T --- V 330
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 577246588 590 Y L V G MND G TM P QPVTASSL - ITD EE KKY F eqqanvelsptsdilqmdeafvc YVA M TRAK GDVTF SYS 656
Cdd:pfam13361 331 F L A G LEE G IF P SYRSIKDE g NLE EE RRL F ----------------------- YVA I TRAK KRLYI SYS 375
PRK10919
PRK10919 ATP-dependent DNA helicase Rep; Provisional
326-654
6.09e-04
ATP-dependent DNA helicase Rep; Provisional
Pssm-ID: 182838 [Multi-domain]
Cd Length: 672
Bit Score: 44.06
E-value: 6.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 326 KQLR Y Q D I AILYR DESYAYL F DSI L PLYN IPY N I DTKR S MTHH P VMEMIRSLIE V IQSNWQVNPM LR LLK T dvl TASYLK 405
Cdd:PRK10919 338 NKTQ Y K D Y AILYR GNHQSRV F EKF L MQNR IPY K I SGGT S FFSR P EIKDLLAYLR V LTNPDDDSAF LR IVN T --- PKREIG 414
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 406 S A Y L VD L L E n FVLE R giygkrwl DDE LF NV ------- EHF S KM G ----- R KA H K L T E DE R NTFEQV V KLKK D V I DK I lhf 473
Cdd:PRK10919 415 P A T L QK L G E - WAMT R -------- NKS LF TA sfdmgls QTL S GR G yeslt R FT H W L A E IQ R LAEREP V AAVR D L I HG I --- 482
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 474 ekqmsqaetvk D fataf YES ME Y FEL P NQLMT E R deldlngnhe KAEEID Q IWNGLIQI L -- DD L vlvfg DEPM SMERFL 551
Cdd:PRK10919 483 ----------- D ----- YES WL Y ETS P SPKAA E M ---------- RMKNVN Q LFSWMTEM L eg SE L ----- DEPM TLTQVV 531
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 577246588 552 EV F DI g LEQL E FVMIPQT LDQV SIG T MDLA K VDNKQH VYLVGM ND G TM P Q pvt A SS L it DE E kkyfeqqa N VE lsptsdi 631
Cdd:PRK10919 532 TR F TL - RDMM E RGESEEE LDQV QLM T LHAS K GLEFPY VYLVGM EE G LL P H --- Q SS I -- DE D -------- N ID ------- 590
330 340
....*....|....*....|...
gi 577246588 632 lqm D E AFVC YV AM TRA KGDV TF S 654
Cdd:PRK10919 591 --- E E RRLA YV GI TRA QKEL TF T 610
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
