|
Name |
Accession |
Description |
Interval |
E-value |
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
241-473 |
7.78e-57 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 188.58 E-value: 7.78e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 241 ERLAWLESQRHQFLRHLSHELKTPLASMREGTELLADQVvGPLTPEQKEVVDILDGSSRNLQKLIEQLLDYNRklVDSAT 320
Cdd:COG2205 7 EELEELERLKSEFLANVSHELRTPLTSILGAAELLLDEE-DLSPEERRELLEIIRESAERLLRLIEDLLDLSR--LESGK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 321 ---ELEAVDIAPLVDMVVSAHSLPARAKMMHTDVDLEAERCI--AEPMLLMSVLDNLYSNAVHYGAESGNICIRSRSQGS 395
Cdd:COG2205 84 lslELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLvyADPELLEQVLANLLDNAIKYSPPGGTITISARREGD 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 554317046 396 TVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKgaVKGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLPLPAS 473
Cdd:COG2205 164 GVRISVSDNGPGIPEEELERIFERFYRGDNSRG--EGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLPLAES 239
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
145-471 |
4.57e-56 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 189.35 E-value: 4.57e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 145 ANTEMVQATRTVVYSRGQQLQQEIAERGQFFGWQALVLFLVSLAMVLLFTRMIIGPVKGIERMINRLGEGRSLGNTVTFT 224
Cdd:COG0642 5 LLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 225 GPRELRSVGQRIIWLSERLAWLESQRHQFLRHLSHELKTPLASMREGTELLADQVvgplTPEQKEVVDILDGSSRNLQKL 304
Cdd:COG0642 85 LLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEEL----DEEQREYLETILRSADRLLRL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 305 IEQLLDYNRklVDSAT---ELEAVDIAPLVDMVVSAHSLPARAKMMHTDVDLEAERCIAE--PMLLMSVLDNLYSNAVHY 379
Cdd:COG0642 161 INDLLDLSR--LEAGKlelEPEPVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPTVRgdPDRLRQVLLNLLSNAIKY 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 380 GAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKGavKGSGLGLSIARDCIRRMQGEIQLVDDKA 459
Cdd:COG0642 239 TPEGGTVTVSVRREGDRVRISVEDTGPGIPPEDLERIFEPFFRTDPSRRG--GGTGLGLAIVKRIVELHGGTIEVESEPG 316
|
330
....*....|..
gi 554317046 460 QEVCFRISLPLP 471
Cdd:COG0642 317 KGTTFTVTLPLA 328
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
110-470 |
1.78e-54 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 187.07 E-value: 1.78e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 110 LYQALRQDLNALAQLQCKDSGPEAAAAARLEAFANANTEMVQATRTVVYSRGQQLQQEIAERGQFFGWQALVLFLVSLAM 189
Cdd:COG5002 28 LLLLLLLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 190 VLLFTRMIIGPVKGIERMINRLGEGRSLGNTVTFTGPRELRSVGQRIIwlsERLAWLESQRHQFLRHLSHELKTPLASMR 269
Cdd:COG5002 108 LALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDI---TELERLEQMRREFVANVSHELRTPLTSIR 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 270 EGTELLADQVVGPlTPEQKEVVDILDGSSRNLQKLIEQLLDYNRklVDSAT---ELEAVDIAPLVDMVVSAHSLPARAKM 346
Cdd:COG5002 185 GYLELLLDGAADD-PEERREYLEIILEEAERLSRLVNDLLDLSR--LESGElklEKEPVDLAELLEEVVEELRPLAEEKG 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 347 MHTDVDLEAERCI--AEPMLLMSVLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGS 424
Cdd:COG5002 262 IELELDLPEDPLLvlGDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREEDDQVRISVRDTGIGIPEEDLPRIFERFYRVD 341
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 554317046 425 HQRKGAVKGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLPL 470
Cdd:COG5002 342 KSRSRETGGTGLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITLPL 387
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
164-470 |
7.51e-33 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 127.99 E-value: 7.51e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 164 LQQEIAERGQFFGWQALVLFLVSLAMVLLFTRMIIGPVKGIERMINRLGEGRSLGNTVTFTGPRELRSVGQRIIWLSERL 243
Cdd:COG4191 44 LALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLLLLLLEALLLLLLAALDAEENAELEELERDITELERAE 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 244 AWLESQRHQfLRH-------------LSHELKTPLASMREGTELLADQVVGPLTPEQ-KEVVDILDGSSRNLQKLIEQLL 309
Cdd:COG4191 124 EELRELQEQ-LVQseklaalgelaagIAHEINNPLAAILGNAELLRRRLEDEPDPEElREALERILEGAERAAEIVRSLR 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 310 DYNRKlvdSATELEAVDIAPLVDMVVS--AHSLPARAKMMHTDVDLEAERCIAEPMLLMSVLDNLYSNAVH--YGAESGN 385
Cdd:COG4191 203 AFSRR---DEEEREPVDLNELIDEALEllRPRLKARGIEVELDLPPDLPPVLGDPGQLEQVLLNLLINAIDamEEGEGGR 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 386 ICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQgshqRKGAVKGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFR 465
Cdd:COG4191 280 ITISTRREGDYVVISVRDNGPGIPPEVLERIFEPFFT----TKPVGKGTGLGLSISYGIVEKHGGRIEVESEPGGGTTFT 355
|
....*
gi 554317046 466 ISLPL 470
Cdd:COG4191 356 ITLPL 360
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
164-472 |
3.49e-30 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 122.26 E-value: 3.49e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 164 LQQEIAERGQFFGWQALVLFLVSLAMVLLFTRMIIGPVKGIERMINRLGEGRSLgnTVTFTGPRELRSVGQRIIWLSERL 243
Cdd:PRK11100 173 MAPFIKRSERRILWAGALLLGIALLIGAGVVWWLNRSIRRLTRYADAVTEGKPV--PLPKLGSSELRELAQALESMRVKL 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 244 ---AWLEsqrhQFLRHLSHELKTPLASMREGTELLADqvvgPLTPEQKE--VVDILDGSSRnLQKLIEQLLDY----NRK 314
Cdd:PRK11100 251 egkAYVE----QYVQTLTHELKSPLAAIRGAAELLQE----DPPPEDRArfTGNILTQSAR-LQQLIDRLLELarleQRQ 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 315 LVDsatELEAVDIAPLVDMVVSAHSLPARAKMMHTDVDLEAERCIAEPMLLMSVLDNLYSNAVHYGAESGNICIRSRSQG 394
Cdd:PRK11100 322 ELE---VLEPVALAALLEELVEAREAQAAAKGITLRLRPDDARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDG 398
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 554317046 395 STVYIDVVNSGEPIPQTEREMIFEPFFqgSHQRK-GAVKGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLPLPA 472
Cdd:PRK11100 399 EQVALSVEDQGPGIPDYALPRIFERFY--SLPRPaNGRKSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLPRHF 475
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
240-475 |
8.70e-30 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 120.45 E-value: 8.70e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 240 SERL-AWlesqrHQFLRHLSHELKTPLASMREGTELLADQVVGPLTPEQ---KEVVDILDGSSRNLQKLIEQLLDYNRKl 315
Cdd:COG5000 195 AERLaAW-----GELARRIAHEIKNPLTPIQLSAERLRRKLADKLEEDRedlERALDTIIRQVDRLKRIVDEFLDFARL- 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 316 vdSATELEAVDIAPLVDMVVSAHSLPARAKMMHTDVDLEAERCIAE--PMLLMSVLDNLYSNAVHYGAESGNICIRSRSQ 393
Cdd:COG5000 269 --PEPQLEPVDLNELLREVLALYEPALKEKDIRLELDLDPDLPEVLadRDQLEQVLINLLKNAIEAIEEGGEIEVSTRRE 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 394 GSTVYIDVVNSGEPIPQTEREMIFEPFFqgSHQRkgavKGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLPLPAS 473
Cdd:COG5000 347 DGRVRIEVSDNGPGIPEEVLERIFEPFF--TTKP----KGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLPLAEE 420
|
..
gi 554317046 474 DK 475
Cdd:COG5000 421 AE 422
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
239-474 |
1.32e-28 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 116.10 E-value: 1.32e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 239 LSERLAWLESQRH--QFLRHLSHELKTPLASMREGTELLADQVVGPltpEQKEVVDILDGSSRNLQKLIEQLLDYNRKlv 316
Cdd:COG3852 122 LERELRRAEKLAAvgELAAGLAHEIRNPLTGIRGAAQLLERELPDD---ELREYTQLIIEEADRLNNLVDRLLSFSRP-- 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 317 dSATELEAVDIAPLVDMVVS-AHSLPARAKMMHTDVDLEAERCIAEPMLLMSVLDNLYSNAVHYGAESGNICIRSRSQ-- 393
Cdd:COG3852 197 -RPPEREPVNLHEVLERVLElLRAEAPKNIRIVRDYDPSLPEVLGDPDQLIQVLLNLVRNAAEAMPEGGTITIRTRVErq 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 394 --------GSTVYIDVVNSGEPIPQTEREMIFEPFFQGshqrKGavKGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFR 465
Cdd:COG3852 276 vtlgglrpRLYVRIEVIDNGPGIPEEILDRIFEPFFTT----KE--KGTGLGLAIVQKIVEQHGGTIEVESEPGKGTTFR 349
|
....*....
gi 554317046 466 ISLPLPASD 474
Cdd:COG3852 350 IYLPLEQAE 358
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
3-473 |
2.91e-26 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 111.42 E-value: 2.91e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 3 RWSVFPRSLRQLVMLAFLLILLPLLVLAWQAWQSLNALSDQAAVTNRSTLIDARRSEAMTNVALEMERSYRQYCVLDDPT 82
Cdd:COG4251 22 LLLLLVLLLALALLLLLALLVLLLLLIRLLLLLLLSLLALLLLLLLLLLLLLVLAALALLLLLLLLELALVLLALLLVLL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 83 LAKVYQSQRKRYSDMLDAHAGVLPDDKLYQALRQDLNALAQLQCKDSGPEAAAAARLEAFANANTEMVQATRTVVYSRGQ 162
Cdd:COG4251 102 LLLALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLLLLLLLLLLLLALILALLLAALAELELL 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 163 QLQQEIAERGQFFGWQALVLFLVsLAMVLLFTRMIIGPVKGIERMINRLGEGRSLGNTVTFTGPRELRSVGQRIIWLSER 242
Cdd:COG4251 182 LLLLLVLLLLLLLLLLLLLLLLR-LLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLE 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 243 LAWLESQRHQFLRHL--------------SHELKTPLASMREGTELLADQVVGPLTPEQKEVVDILDGSSRNLQKLIEQL 308
Cdd:COG4251 261 LEELEEELEERTAELersneeleqfayvaSHDLREPLRKISGFSQLLEEDYGDKLDEEGREYLERIRDAAERMQALIDDL 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 309 LDYNRkLVDSATELEAVDIAPLVDMVVSAHSLPARAKmmhtDVDLEAE---RCIAEPMLLMSVLDNLYSNAVHYGA--ES 383
Cdd:COG4251 341 LAYSR-VGRQELEFEPVDLNELLEEVLEDLEPRIEER----GAEIEVGplpTVRGDPTLLRQVFQNLISNAIKYSRpgEP 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 384 GNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFfqgshQR---KGAVKGSGLGLSIARDCIRRMQGEIQLVDDKAQ 460
Cdd:COG4251 416 PRIEIGAEREGGEWVFSVRDNGIGIDPEYAEKIFEIF-----QRlhsRDEYEGTGIGLAIVKKIVERHGGRIWVESEPGE 490
|
490
....*....|...
gi 554317046 461 EVCFRISLPLPAS 473
Cdd:COG4251 491 GATFYFTLPKAPA 503
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
360-471 |
4.43e-26 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 101.96 E-value: 4.43e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 360 AEPMLLMSVLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGShQRKGAVKGSGLGLS 439
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTD-KRSRKIGGTGLGLS 79
|
90 100 110
....*....|....*....|....*....|..
gi 554317046 440 IARDCIRRMQGEIQLVDDKAQEVCFRISLPLP 471
Cdd:smart00387 80 IVKKLVELHGGEISVESEPGGGTTFTITLPLE 111
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
255-470 |
1.07e-24 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 107.81 E-value: 1.07e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 255 RHL---SHELKTPLASMREGTELLADqvvGPLTPEQKEVVDILDGSSRNLQKLIEQLLDYNRKLVDSAT-ELEAVDIAPL 330
Cdd:PRK15347 400 EHLttiSHEIRTPLNGVLGALELLQN---TPLTAEQMDLADTARQCTLSLLAIINNLLDFSRIESGQMTlSLEETALLPL 476
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 331 VDMVVSAHSLPARAK--MMHT----DVDLEAErciAEPMLLMSVLDNLYSNAVHYgAESGNICIRSRSQGSTVYIDVVNS 404
Cdd:PRK15347 477 LDQAMLTIQGPAQSKslTLRTfvgaHVPLYLH---LDSLRLRQILVNLLGNAVKF-TETGGIRLRVKRHEQQLCFTVEDT 552
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 554317046 405 GEPIPQTEREMIFEPFFQGSHQRKGavkgSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLPL 470
Cdd:PRK15347 553 GCGIDIQQQQQIFTPFYQADTHSQG----TGLGLTIASSLAKMMGGELTLFSTPGVGSCFSLVLPL 614
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
180-470 |
1.11e-23 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 103.47 E-value: 1.11e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 180 LVLFLVSLAMVLLFTRMIIGPVKGIERMINRLgegrSLGNTVTF----TGPRELRSVGQRIIWLSERLAWLESQRHQFLR 255
Cdd:PRK09470 173 LVTMLVSTPLLLWLAWSLAKPARKLKNAADEV----AQGNLRQHpeleTGPQEFRQAGASFNQMVTALERMMTSQQRLLS 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 256 HLSHELKTPLASMREGTELLADQVvGpltpEQKEVVDIlDGSSRNLQKLIEQLLDYNRKLVDSATELEAVDIAPLVDMVV 335
Cdd:PRK09470 249 DISHELRTPLTRLQLATALLRRRQ-G----ESKELERI-ETEAQRLDSMINDLLVLSRNQQKNHLERETFKANSLWSEVL 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 336 SAHSLPA--RAKMMHTDVDLEAERCIAEPMLLMSVLDNLYSNAVHYGAESgnICIRSRSQGSTVYIDVVNSGEPIPQTER 413
Cdd:PRK09470 323 EDAKFEAeqMGKSLTVSAPPGPWPINGNPNALASALENIVRNALRYSHTK--IEVAFSVDKDGLTITVDDDGPGVPEEER 400
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 554317046 414 EMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLPL 470
Cdd:PRK09470 401 EQIFRPFYRVDEARDRESGGTGLGLAIVENAIQQHRGWVKAEDSPLGGLRLTIWLPL 457
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
180-472 |
1.36e-22 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 99.98 E-value: 1.36e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 180 LVLFLVSLAMVLLFTRMIIGPVKGIERMINRLGEGrSLGNTVTFTGPRELRSVGQRIIWLSERLAWLESQRHQFLRHLSH 259
Cdd:PRK09467 160 LAIGLLSVAGGWLFIRIQNRPLVALEHAALQVGKG-EIPPPLREYGASEVRSVTRAFNQMAAGIKQLEDDRTLLMAGVSH 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 260 ELKTPLASMREGTELLAdqvvgpltPEQ---KE--VVDILDgssrnLQKLIEQLLDYNRKlvDSATELEAVDIAPLVDMV 334
Cdd:PRK09467 239 DLRTPLTRIRLATEMMS--------EEDgylAEsiNKDIEE-----CNAIIEQFIDYLRT--GQEMPMEMADLNALLGEV 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 335 VSAHSlpARAKMMHTDVDLEAERCIAEPMLLMSVLDNLYSNAVHYGaeSGNICIRSRSQGSTVYIDVVNSGEPIPQTERE 414
Cdd:PRK09467 304 IAAES--GYEREIETALQPGPIEVPMNPIAIKRALANLVVNAARYG--NGWIKVSSGTEGKRAWFQVEDDGPGIPPEQLK 379
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 554317046 415 MIFEPFFQGSHQRKGAvkGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLPLPA 472
Cdd:PRK09467 380 HLFQPFTRGDSARGSS--GTGLGLAIVKRIVDQHNGKVELGNSEEGGLSARAWLPLTT 435
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
362-471 |
1.34e-20 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 86.65 E-value: 1.34e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 362 PMLLMSVLDNLYSNAVHYGAESGNICIRsRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKGavkGSGLGLSIA 441
Cdd:pfam02518 3 ELRLRQVLSNLLDNALKHAAKAGEITVT-LSEGGELTLTVEDNGIGIPPEDLPRIFEPFSTADKRGGG---GTGLGLSIV 78
|
90 100 110
....*....|....*....|....*....|
gi 554317046 442 RDCIRRMQGEIQLVDDKAQEVCFRISLPLP 471
Cdd:pfam02518 79 RKLVELLGGTITVESEPGGGTTVTLTLPLA 108
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
184-440 |
1.17e-19 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 91.23 E-value: 1.17e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 184 LVSLAMVLLFTRMIIGPVKGIERMINRLGEGrSLGNTVTFTGPRELRSVGQRIIWLSERLAWLESQRHQFLRHLSHELKT 263
Cdd:PRK10549 175 LLAALATFLLARGLLAPVKRLVEGTHKLAAG-DFTTRVTPTSRDELGRLAQDFNQLASTLEKNEQMRRDFMADISHELRT 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 264 PLASMREGTELLADQVVGPlTPE-----QKEVVdildgssrNLQKLIEQL----------LDYnRKlvdsatelEAVDIA 328
Cdd:PRK10549 254 PLAVLRGELEAIQDGVRKF-TPEsvaslQAEVG--------TLTKLVDDLhqlslsdegaLAY-RK--------TPVDLV 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 329 PLVDMVVSA--HSLPARAKMMHTDVDLEAeRCIAEPMLLMSVLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDVVNSGE 406
Cdd:PRK10549 316 PLLEVAGGAfrERFASRGLTLQLSLPDSA-TVFGDPDRLMQLFNNLLENSLRYTDSGGSLHISAEQRDKTLRLTFADSAP 394
|
250 260 270
....*....|....*....|....*....|....
gi 554317046 407 PIPQTEREMIFEPFFQGSHQRKGAVKGSGLGLSI 440
Cdd:PRK10549 395 GVSDEQLQKLFERFYRTEGSRNRASGGSGLGLAI 428
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
226-469 |
1.24e-19 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 91.30 E-value: 1.24e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 226 PRELRSVGQRIIWLSERLAWLESQRHQFLRHLSHELKTPLASMREGTELLADQvvgPLTpeQKEVVDILDGSSRNLQKL- 304
Cdd:TIGR01386 217 PAELRELAQSFNAMLGRLEDAFQRLSQFSADLAHELRTPLTNLLGQTQVALSQ---PRT--GEEYREVLESNLEELERLs 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 305 --IEQLL-----DYNRklvdSATELEAVDIAPLVDMVVSAHSLPARAKMMHTDVDLEAeRCIAEPMLLMSVLDNLYSNAV 377
Cdd:TIGR01386 292 rmVSDMLflaraDNGQ----LALERVRLDLAAELAKVAEYFEPLAEERGVRIRVEGEG-LVRGDPQMFRRAISNLLSNAL 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 378 HYGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGEIQlVDD 457
Cdd:TIGR01386 367 RHTPDGGTITVRIERRSDEVRVSVSNPGPGIPPEHLSRLFDRFYRVDPARSNSGEGTGLGLAIVRSIMEAHGGRAS-AES 445
|
250
....*....|..
gi 554317046 458 KAQEVCFRISLP 469
Cdd:TIGR01386 446 PDGKTRFILRFP 457
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
253-470 |
4.97e-18 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 87.27 E-value: 4.97e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 253 FLRHLSHELKTPLASMREGTELLADQvvgPLTPEQKEVVDILDGSSRNLQKLIEQLLDYnrklvdSATELEAVDIAPLVD 332
Cdd:PRK11466 447 FLAAMSHEIRTPLYGILGTAQLLADN---PALNAQRDDLRAITDSGESLLTILNDILDY------SAIEAGGKNVSVSDE 517
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 333 MVVSAHSLPARAKMMHTDVDLEAERCIAE------------PMLLMSVLDNLYSNAVHYgAESGNICIRSRSQGSTVYID 400
Cdd:PRK11466 518 PFEPRPLLESTLQLMSGRVKGRPIRLATDiaddlptalmgdPRRIRQVITNLLSNALRF-TDEGSIVLRSRTDGEQWLVE 596
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 401 VVNSGEPIPQTEREMIFEPFFQGSHQRkgavKGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLPL 470
Cdd:PRK11466 597 VEDSGCGIDPAKLAEIFQPFVQVSGKR----GGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPL 662
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
212-475 |
1.14e-17 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 85.79 E-value: 1.14e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 212 GEGRSLGNTVTF---TGPRELRSVGQRiiwlSERLAWLesqrHQFLRHLSHELKTPLASMREGTELLADQVVGPLTPEQ- 287
Cdd:PRK11360 357 THGEMIGALVIFsdlTERKRLQRRVAR----QERLAAL----GELVAGVAHEIRNPLTAIRGYVQIWRQQTSDPPSQEYl 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 288 ----KEVvdildgssRNLQKLIEQLLDYNRKlvdSATELEAVDIAPLVDMVV-----SAHSlpARAKMmHTDVDLEAERC 358
Cdd:PRK11360 429 svvlREV--------DRLNKVIDQLLEFSRP---RESQWQPVSLNALVEEVLqlfqtAGVQ--ARVDF-ETELDNELPPI 494
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 359 IAEPMLLMSVLDNLYSNAVHYGAESGNICIRSRSQGST-VYIDVVNSGEPIPQTEREMIFEPFFQGShqrkgaVKGSGLG 437
Cdd:PRK11360 495 WADPELLKQVLLNILINAVQAISARGKIRIRTWQYSDGqVAVSIEDNGCGIDPELLKKIFDPFFTTK------AKGTGLG 568
|
250 260 270
....*....|....*....|....*....|....*...
gi 554317046 438 LSIARDCIRRMQGEIQLVDDKAQEVCFRISLPLPASDK 475
Cdd:PRK11360 569 LALSQRIINAHGGDIEVESEPGVGTTFTLYLPINPQGN 606
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
179-471 |
4.36e-17 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 83.11 E-value: 4.36e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 179 ALVLFL-VSLAM-VLLFTRMIIGPVKGIERMINRLGEGRsLGNTVTFTGPRELRSVGQRIIWLSERLAWLESQRHQFLRH 256
Cdd:PRK10604 140 ALLALIgLSLAFpVFLWMRPHWQDMLKLEAAAQRLGDGH-LAERIHFDEGSSLERLGVAFNQMADNINALIASKKQLIDG 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 257 LSHELKTPLASMREGTELLADqvvgPLTPEQKEVVDILDgssrNLQKLIEQLLDYNRklVD---SATELEAVDIAPLVDM 333
Cdd:PRK10604 219 IAHELRTPLVRLRYRLEMSDN----LSAAESQALNRDIG----QLEALIEELLTYAR--LDrpqNELHLSEPDLPAWLST 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 334 VVSAHSLPARAKMMHTDVDLEAERCIAEPMLLMSVLDNLYSNAVHYGAesGNICIRSRSQGSTVYIDVVNSGEPIPQTER 413
Cdd:PRK10604 289 HLADIQAVTPEKTVRLDTPHQGDYGALDMRLMERVLDNLLNNALRYAH--SRVRVSLLLDGNQACLIVEDDGPGIPPEER 366
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 554317046 414 EMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLPLP 471
Cdd:PRK10604 367 ERVFEPFVRLDPSRDRATGGCGLGLAIVHSIALAMGGSVNCDESELGGARFSFSWPVW 424
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-470 |
7.89e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 75.83 E-value: 7.89e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 365 LMSVLDNLYSNAVHYGAESgnICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKGAVKGSGLGLSIARDC 444
Cdd:cd16949 1 LARALENVLRNALRYSPSK--ILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSARDRESGGTGLGLAIAERA 78
|
90 100
....*....|....*....|....*.
gi 554317046 445 IRRMQGEIQLVDDKAQEVCFRISLPL 470
Cdd:cd16949 79 IEQHGGKIKASNRKPGGLRVRIWLPA 104
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
240-472 |
1.50e-16 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 82.78 E-value: 1.50e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 240 SERLAWLESQRHQ----FLRHLSHELKTPLASMREGTELL-----ADQvvGPLTPEQKEVVDILDGSSRnlqkLIEQLLD 310
Cdd:PRK10490 650 SEEQARLASEREQlrnaLLAALSHDLRTPLTVLFGQAEILtldlaSEG--SPHARQASEIRQQVLNTTR----LVNNLLD 723
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 311 YNR----------------KLVDSATELeavdIAPLVDMVVSAHSLPARAKMMHTDVDLeAERciaepmllmsVLDNLYS 374
Cdd:PRK10490 724 MARiqsggfnlrkewltleEVVGSALQM----LEPGLSGHPINLSLPEPLTLIHVDGPL-FER----------VLINLLE 788
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 375 NAVHYGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGshQRKGAVKGSGLGLSIARDCIRRMQGEIQL 454
Cdd:PRK10490 789 NAVKYAGAQAEIGIDAHVEGERLQLDVWDNGPGIPPGQEQLIFDKFARG--NKESAIPGVGLGLAICRAIVEVHGGTIWA 866
|
250
....*....|....*...
gi 554317046 455 VDDKAQEVCFRISLPLPA 472
Cdd:PRK10490 867 ENRPEGGACFRVTLPLET 884
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
362-470 |
6.95e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 73.23 E-value: 6.95e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 362 PMLLMSVLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFqgshQRKGAVKGSGLGLSIA 441
Cdd:cd16943 1 PSQLNQVLLNLLVNAAQAMEGRGRITIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFF----TTKPVGEGTGLGLSLS 76
|
90 100
....*....|....*....|....*....
gi 554317046 442 RDCIRRMQGEIQLVDDKAQEVCFRISLPL 470
Cdd:cd16943 77 YRIIQKHGGTIRVASVPGGGTRFTIILPI 105
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-468 |
2.10e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 72.55 E-value: 2.10e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 365 LMSVLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKGAVKGSGLGLSIARDC 444
Cdd:cd16947 21 LQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLEDSRNSAKQGNGLGLTITKRL 100
|
90 100
....*....|....*....|....
gi 554317046 445 IRRMQGEIQLVDDKAQEVCFRISL 468
Cdd:cd16947 101 AESMGGSIYVNSKPYEKTVFTVTL 124
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
305-470 |
4.83e-15 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 76.81 E-value: 4.83e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 305 IEQLLDYNRKLVDSATELEAVDIAPLVDMVVSA--HSLPARAKMMHTDVDLEAERCIAE----PMLLMSVLDNLYSNAVH 378
Cdd:COG3290 216 YDEALEYIDEISEELQELIDSLLSRIGNPVLAAllLGKAARARERGIDLTIDIDSDLPDlplsDTDLVTILGNLLDNAIE 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 379 Y----GAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFF--QGSHqrkgavkGSGLGLSIARDCIRRMQGEI 452
Cdd:COG3290 296 AveklPEEERRVELSIRDDGDELVIEVEDSGPGIPEELLEKIFERGFstKLGE-------GRGLGLALVKQIVEKYGGTI 368
|
170
....*....|....*...
gi 554317046 453 QLVDDKAQEVCFRISLPL 470
Cdd:COG3290 369 EVESEEGEGTVFTVRLPK 386
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
250-470 |
1.05e-14 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 77.08 E-value: 1.05e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 250 RHQFLRHLSHELKTPLASMREGTELLADQvvgPLTPEQK-EVVDILDGSSRNLQKLIEQLLDYNrKLVDSATELEA--VD 326
Cdd:PRK09959 712 KSQFLATMSHEIRTPISSIMGFLELLSGS---GLSKEQRvEAISLAYATGQSLLGLIGEILDVD-KIESGNYQLQPqwVD 787
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 327 IAPLVDMvvSAHSLPARAKMMHTDVDLEAE-----RCIAEPMLLMSVLDNLYSNAVHYGAEsGNICIRSrsqgSTVYID- 400
Cdd:PRK09959 788 IPTLVQN--TCHSFGAIAASKSIALSCSSTfpdhyLVKIDPQAFKQVLSNLLSNALKFTTE-GAVKITT----SLGHIDd 860
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 554317046 401 --------VVNSGEPIPQTEREMIFEPFFQGSHQRKGAvkGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLPL 470
Cdd:PRK09959 861 nhavikmtIMDSGSGLSQEEQQQLFKRYSQTSAGRQQT--GSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIPV 936
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
253-476 |
1.12e-14 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 76.52 E-value: 1.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 253 FLRHLSHELKTPLASMREGTELLADQvvgPLTPEQKEVVDILDGSSRNLQKLIEQLLD---YNRKLVDSATEleAVDIAP 329
Cdd:PRK11091 286 FISTISHELRTPLNGIVGLSRILLDT---ELTAEQRKYLKTIHVSAITLGNIFNDIIDmdkMERRKLQLDNQ--PIDFTD 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 330 LVDMVVSAHSLPARAKMMHTDVDLEA---ERCIAEPMLLMSVLDNLYSNAVHYGAEsGNICIR-SRSQGSTVYIDVVNSG 405
Cdd:PRK11091 361 FLADLENLSGLQAEQKGLRFDLEPLLplpHKVITDGTRLRQILWNLISNAVKFTQQ-GGVTVRvRYEEGDMLTFEVEDSG 439
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 554317046 406 EPIPQTEREMIFEPFFQ--GSHQRKGAVkGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLPLPASDKH 476
Cdd:PRK11091 440 IGIPEDELDKIFAMYYQvkDSHGGKPAT-GTGIGLAVSKRLAQAMGGDITVTSEEGKGSCFTLTIHAPAVAEE 511
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
258-470 |
3.93e-14 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 74.24 E-value: 3.93e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 258 SHELKTPLASMREGTELLADQVvgplTPEQKEVVDILDGSSRNLQKLIEQLLDYNRKlvdSATELEAVDIAPLVDMVVSA 337
Cdd:COG5809 278 AHEIRNPLTSLKGFIQLLKDTI----DEEQKTYLDIMLSELDRIESIISEFLVLAKP---QAIKYEPKDLNTLIEEVIPL 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 338 hsLPARAkmMHTDVDLEAERCIAEPMLLMS------VLDNLYSNAVHYGAESGNICIRSRSQ-GSTVYIDVVNSGEPIPQ 410
Cdd:COG5809 351 --LQPQA--LLKNVQIELELEDDIPDILGDenqlkqVFINLLKNAIEAMPEGGNITIETKAEdDDKVVISVTDEGCGIPE 426
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 554317046 411 TEREMIFEPFFQGSHqrkgavKGSGLGLSIARDCIRRMQGEIQlVDDKAQE-VCFRISLPL 470
Cdd:COG5809 427 ERLKKLGEPFYTTKE------KGTGLGLMVSYKIIEEHGGKIT-VESEVGKgTTFSITLPI 480
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
368-469 |
4.26e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 67.86 E-value: 4.26e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 368 VLDNLYSNAVHYGaeSGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRkgAVKGSGLGLSIARDCIRR 447
Cdd:cd16950 4 VLSNLVDNALRYG--GGWVEVSSDGEGNRTRIQVLDNGPGIAPEEVDELFQPFYRGDNAR--GTSGTGLGLAIVQRISDA 79
|
90 100
....*....|....*....|..
gi 554317046 448 MQGEIQLVDDKAQEVCFRISLP 469
Cdd:cd16950 80 HGGSLTLANRAGGGLCARIELP 101
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
368-470 |
8.23e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 67.52 E-value: 8.23e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 368 VLDNLYSNAVHYGAEsGNICIRSRSQGST-----VYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKGAVKGSGLGLSIAR 442
Cdd:cd16922 4 ILLNLLGNAIKFTEE-GEVTLRVSLEEEEedgvqLRFSVEDTGIGIPEEQQARLFEPFSQADSSTTRKYGGTGLGLAISK 82
|
90 100
....*....|....*....|....*...
gi 554317046 443 DCIRRMQGEIQLVDDKAQEVCFRISLPL 470
Cdd:cd16922 83 KLVELMGGDISVESEPGQGSTFTFTLPL 110
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
253-470 |
1.75e-13 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 73.08 E-value: 1.75e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 253 FLRHLSHELKTPLASMREGTELLADQVvgpLTPEQKEVVDILDGSSRNLQKLIEQLLDYnrklvdSATELEAVDIAPL-- 330
Cdd:PRK10841 450 FLATVSHELRTPLYGIIGNLDLLQTKE---LPKGVDRLVTAMNNSSSLLLKIISDILDF------SKIESEQLKIEPRef 520
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 331 ----VDMVVSAHSLPARAK-------MMHTDVdleAERCIAEPMLLMSVLDNLYSNAVHYgAESGNICIRSRSQGSTVYI 399
Cdd:PRK10841 521 spreVINHITANYLPLVVKkrlglycFIEPDV---PVALNGDPMRLQQVISNLLSNAIKF-TDTGCIVLHVRVDGDYLSF 596
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 554317046 400 DVVNSGEPIPQTEREMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLPL 470
Cdd:PRK10841 597 RVRDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLINMMDGDISVDSEPGMGSQFTIRIPL 667
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
249-313 |
2.59e-13 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 64.54 E-value: 2.59e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 554317046 249 QRHQFLRHLSHELKTPLASMREGTELLADqvvGPLTPEQKEVVDILDGSSRNLQKLIEQLLDYNR 313
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLRD---EKLDEEQREYLETILRSAERLLRLINDLLDLSR 62
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
253-476 |
2.63e-13 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 72.57 E-value: 2.63e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 253 FLRHLSHELKTPLasmregtellaDQVVG--------PLTPEQKEVVDILDGSSRNLQKLIEQLLDYNrKLVDSATELEA 324
Cdd:PRK11107 296 FLANMSHELRTPL-----------NGVIGftrqtlktPLTPTQRDYLQTIERSANNLLAIINDILDFS-KLEAGKLVLEN 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 325 V--DIAPLVDMVVS--AHSlpARAKMMHTDVDLEA---ERCIAEPMLLMSVLDNLYSNAVHYgAESGNICIRSRSQGS-- 395
Cdd:PRK11107 364 IpfSLRETLDEVVTllAHS--AHEKGLELTLNIDPdvpDNVIGDPLRLQQIITNLVGNAIKF-TESGNIDILVELRALsn 440
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 396 ---TVYIDVVNSGEPIPQTEREMIFEPFFQG--SHQRK-GavkGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLP 469
Cdd:PRK11107 441 tkvQLEVQIRDTGIGISERQQSQLFQAFRQAdaSISRRhG---GTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHLP 517
|
250
....*....|..
gi 554317046 470 L-----PASDKH 476
Cdd:PRK11107 518 LdlnpnPIIDGL 529
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
258-475 |
4.05e-13 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 70.97 E-value: 4.05e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 258 SHELKTPLASMREGTELLADQVvgPLTPEQKEVVDILDGSSRNLQKLIEQLLDYNRKlvdSATELEAVDIAPLVDMVVSA 337
Cdd:PRK10364 245 AHEIRNPLSSIKGLAKYFAERA--PAGGEAHQLAQVMAKEADRLNRVVSELLELVKP---THLALQAVDLNDLINHSLQL 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 338 HSLPARAK--MMHTDVDLEAERCIAEPMLLMSVLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREM 415
Cdd:PRK10364 320 VSQDANSReiQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEA 399
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 416 IFEPFFQGSHQrkgavkGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLPLPASDK 475
Cdd:PRK10364 400 IFTPYFTTKAE------GTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLPVNITRR 453
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
249-313 |
4.62e-13 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 63.74 E-value: 4.62e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 554317046 249 QRHQFLRHLSHELKTPLASMREGTELLADqvvGPLTPEQKEVVDILDGSSRNLQKLIEQLLDYNR 313
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLD---TELSEEQREYLETILREAERLLRLINDLLDLSR 62
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
247-313 |
2.21e-12 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 61.84 E-value: 2.21e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 554317046 247 ESQRHQFLRHLSHELKTPLASMREGTELLADQVVGPltPEQKEVVDILDGSSRNLQKLIEQLLDYNR 313
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDD--EEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
253-469 |
2.61e-12 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 68.65 E-value: 2.61e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 253 FLRHLSHELKTPLASMREGTELLADQvvgplTPEQKEVVDILDGSSRNLQKLIEQLLDY-------NRKLVdsaTELEAV 325
Cdd:PRK09835 265 FSADIAHEIRTPITNLITQTEIALSQ-----SRSQKELEDVLYSNLEELTRMAKMVSDMlflaqadNNQLI---PEKKML 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 326 DIAPLVDMVVSAhsLPARAKMMHTDVDLEAERCIAE--PMLLMSVLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDVVN 403
Cdd:PRK09835 337 DLADEVGKVFDF--FEAWAEERGVELRFVGDPCQVAgdPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQLVVEN 414
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 554317046 404 SGEPIPQTEREMIFEPFFQ--GSHQRKGavKGSGLGLSIARDCIRRMQGEIQLVDDkAQEVCFRISLP 469
Cdd:PRK09835 415 PGTPIAPEHLPRLFDRFYRvdPSRQRKG--EGSGIGLAIVKSIVVAHKGTVAVTSD-ARGTRFVISLP 479
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
368-469 |
4.46e-12 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 62.51 E-value: 4.46e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 368 VLDNLYSNAVHYGAESGNI-CIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIR 446
Cdd:cd16925 8 VVLNLLSNAFKFTPDGGRIrCILEKFRLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTRAHGGTGLGLSIVKEFVE 87
|
90 100
....*....|....*....|...
gi 554317046 447 RMQGEIQLVDDKAQEVCFRISLP 469
Cdd:cd16925 88 LHGGTVTVSDAPGGGALFQVELP 110
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
361-454 |
4.68e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 62.48 E-value: 4.68e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 361 EPMLLMSVLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKGAvKGSGLGLSI 440
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYSLPRPHSGQ-KSTGLGLAF 79
|
90
....*....|....
gi 554317046 441 ARDCIRRMQGEIQL 454
Cdd:cd16945 80 VQEVAQLHGGRITL 93
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
200-452 |
5.27e-12 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 67.74 E-value: 5.27e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 200 PVKGIERMINRLGEG-RSLGNTVTftgPRELRSVGQRIiwlsERLAWLESQRHQFLR----HLSHELKTPLA-------S 267
Cdd:PRK10815 218 PIEALAKQVRELEEGeREQLDPNP---PRELTSLVRNL----NRLLKNERERYTKYRttltDLTHSLKTPLAvlqstlrS 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 268 MREGTELladqvvgplTPEQKEVVdILDGSSRnlqklIEQLLDY--NRKLVDSATEL---EAVDIAPLVDMVVSAHSLPA 342
Cdd:PRK10815 291 LRSGKQM---------SVEQAEPI-MLEQISR-----ISQQIGYylHRASMRSEHNLlsrELHSVAPLLDNLTSALNKVY 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 343 RAKMMHTDVDLEAERC-IAEPMLLMSVLDNLYSNAVHYGAESgnICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEpff 421
Cdd:PRK10815 356 QRKGVNITLDISPEITfVGEKNDFMEVMGNVLDNACKYCLEF--VEISARQTDEHLHIVVEDDGPGIPESKRELIFD--- 430
|
250 260 270
....*....|....*....|....*....|..
gi 554317046 422 QGshQRKGAVK-GSGLGLSIARDCIRRMQGEI 452
Cdd:PRK10815 431 RG--QRADTLRpGQGLGLSVAREITEQYEGKI 460
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
154-470 |
6.14e-12 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 67.35 E-value: 6.14e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 154 RTVVYSRGQQLQQEIAERGQFFGWQALVLFLVSLAMVLLFTRMIIGPVKGIERMINRLGEGRSLgnTVTFTGPRELRSVG 233
Cdd:COG2972 138 TLVSLIPKSELFRGLFSLRRLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDLV--RLEVSGNDEIGILA 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 234 QRIIWLSERLAWLESQRHQFLRHLSH-ELKT------P------LASMREgtelLAdqvvgpLTPEQKEVVDILDgssrN 300
Cdd:COG2972 216 RSFNEMVERIKELIEEVYELELEKKEaELKAlqaqinPhflfntLNSIRW----LA------ELEDPEEAEEMLE----A 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 301 LQKLIEQLLDYNRKLVDSATELEavdiapLVDMVVSAHSLPARAKM-MHTDVDLEAERCIAEPMLLMSVLDNlysnAVHY 379
Cdd:COG2972 282 LSKLLRYSLSKGDELVTLEEELE------LIKSYLEIQKLRFGDRLeVEIEIDEELLDLLIPKLILQPLVEN----AIEH 351
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 380 GAES----GNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHqrkgavkGSGLGLSIARDCIRRMQGE---I 452
Cdd:COG2972 352 GIEPkeggGTIRISIRKEGDRLVITVEDNGVGMPEEKLEKLLEELSSKGE-------GRGIGLRNVRERLKLYYGEeygL 424
|
330
....*....|....*...
gi 554317046 453 QLVDDKAQEVCFRISLPL 470
Cdd:COG2972 425 EIESEPGEGTTVTIRIPL 442
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
368-469 |
1.43e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 60.86 E-value: 1.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 368 VLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKGAvkGSGLGLSIARDCIRR 447
Cdd:cd16923 4 VFSNLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSRNTE--GAGLGLSIAKAIIEL 81
|
90 100
....*....|....*....|..
gi 554317046 448 MQGEIQLVDDKAQEVcFRISLP 469
Cdd:cd16923 82 HGGSASAEYDDNHDL-FKVRLP 102
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
246-469 |
1.96e-11 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 65.80 E-value: 1.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 246 LESQRHQFLRHLSHELKTPLASMREGTELLADQV-VGPLtpeQKEVVDILDGSSRNLQKLIEQLLDYNRKLVDSATEL-E 323
Cdd:PRK11006 200 LEGARRNFFANVSHELRTPLTVLQGYLEMMQDQPlEGAL---REKALHTMREQTQRMEGLVKQLLTLSKIEAAPTIDLnE 276
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 324 AVDIAPLVDMVV-SAHSLPARAKMMHTDVDlEAERCIAEPMLLMSVLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDVV 402
Cdd:PRK11006 277 KVDVPMMLRVLErEAQTLSQGKHTITFEVD-NSLKVFGNEDQLRSAISNLVYNAVNHTPEGTHITVRWQRVPQGAEFSVE 355
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 554317046 403 NSGEPIPQTEREMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLP 469
Cdd:PRK11006 356 DNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHALSHHDSRLEIESEVGKGTRFSFVLP 422
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
368-470 |
2.64e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 60.14 E-value: 2.64e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 368 VLDNLYSNAVHYGAESgnICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRR 447
Cdd:cd16939 4 ALDNLLRNALRYAHRT--VRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRDRATGGFGLGLAIVHRVALW 81
|
90 100
....*....|....*....|...
gi 554317046 448 MQGEIQLVDDKAQEVCFRISLPL 470
Cdd:cd16939 82 HGGHVECDDSELGGACFRLTWPR 104
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
150-440 |
4.32e-11 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 64.22 E-value: 4.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 150 VQATRTVvYSRGQQLQQEIAErgqffgwQALVLFLVSLAMVLLFTRMIIGPVKGIERMINRLG---EGRSLGN---TVTF 223
Cdd:PRK10755 39 VQATLSA-RNNDEHVMKEIRE-------AVASLLVPSLVMVSLTLLICFQAVRWITRPLAELQkelEARTADNltpIAIH 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 224 TGPRELRSVGQRIIWLSERLAWLESQRHQFLRHLSHELKTPLASMREGTELLADQVVgpltPEQKEVVDILDgssrNLQK 303
Cdd:PRK10755 111 SSTLEIEAVTSALNQLVSRLTSTLDQERLFTADVAHELRTPLAGIRLHLELLEKQHH----IDVAPLIARLD----QMMH 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 304 LIEQLLDYNRKLVDSATEL-EAVDiapLVDMVVsahsLPARAKM--MHT------DVDLEAERCIAE--PMLLMSVLDNL 372
Cdd:PRK10755 183 TVEQLLQLARAGQSFSSGHyQTVK---LLEDVI----LPSQDELseMLEqrqqtlLLPESAADITVQgdATLLRLLLRNL 255
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 554317046 373 YSNAVHYGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQgSHQRKGavkGSGLGLSI 440
Cdd:PRK10755 256 VENAHRYSPEGSTITIKLSQEDGGAVLAVEDEGPGIDESKCGELSKAFVR-MDSRYG---GIGLGLSI 319
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
242-470 |
5.50e-11 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 65.08 E-value: 5.50e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 242 RLAWLESQR---HQFLRH-------------LSHELKTPLASMREGTELlADQVVGPLTPEQKEVVDILDGSSRnLQKLI 305
Cdd:PRK13837 426 ERRRLETERdalERRLEHarrleavgtlasgIAHNFNNILGAILGYAEM-ALNKLARHSRAARYIDEIISAGAR-ARLII 503
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 306 EQLLDYNRKlvdSATELEAVDIAPLVDMVVS--AHSLPARAKMmhtDVDLEAERCIAE--PMLLMSVLDNLYSNAVHYGA 381
Cdd:PRK13837 504 DQILAFGRK---GERNTKPFDLSELVTEIAPllRVSLPPGVEL---DFDQDQEPAVVEgnPAELQQVLMNLCSNAAQAMD 577
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 382 ESGNICIR-SRSQGST--------------VYIDVVNSGEPIPQTEREMIFEPFFQgshQRKGavkGSGLGLSIARDCIR 446
Cdd:PRK13837 578 GAGRVDISlSRAKLRApkvlshgvlppgryVLLRVSDTGAGIDEAVLPHIFEPFFT---TRAG---GTGLGLATVHGIVS 651
|
250 260
....*....|....*....|....
gi 554317046 447 RMQGEIQLVDDKAQEVCFRISLPL 470
Cdd:PRK13837 652 AHAGYIDVQSTVGRGTRFDVYLPP 675
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-452 |
1.10e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 58.63 E-value: 1.10e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 365 LMSVLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKGAVKGSGLGLSIARDC 444
Cdd:cd16946 5 LQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSRNRASGGSGLGLAICHNI 84
|
....*...
gi 554317046 445 IRRMQGEI 452
Cdd:cd16946 85 ALAHGGTI 92
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-469 |
1.87e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 57.80 E-value: 1.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 365 LMSVLDNLYSNAVHYGAES-GNICIRSRSQ-----GSTVY-----IDVVNSGEPIPQTEREMIFEPFFQGSHQrkgavkG 433
Cdd:cd16918 1 LIQVFLNLVRNAAQALAGSgGEIILRTRTQrqvtlGHPRHrlalrVSVIDNGPGIPPDLQDTIFYPMVSGREN------G 74
|
90 100 110
....*....|....*....|....*....|....*.
gi 554317046 434 SGLGLSIARDCIRRMQGEIQlVDDKAQEVCFRISLP 469
Cdd:cd16918 75 TGLGLAIAQNIVSQHGGVIE-CDSQPGHTVFSVSLP 109
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
239-469 |
6.50e-10 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 60.74 E-value: 6.50e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 239 LSERLAWLEsqrhQFLRHLSHELKTPL--ASMR-EGTELLADQVVGPLTPEQKEvvDILDGSSRNLQK---LIEQLLDYN 312
Cdd:PRK09303 144 LLEQLKFKD----RVLAMLAHDLRTPLtaASLAlETLELGQIDEDTELKPALIE--QLQDQARRQLEEierLITDLLEVG 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 313 RKlvdSATELE----AVDIAPLVDMVVS--AHSLPARAKMMHTDVDLEAERCIAEPMLLMSVLDNLYSNAVHYGAESGNI 386
Cdd:PRK09303 218 RT---RWEALRfnpqKLDLGSLCQEVILelEKRWLAKSLEIQTDIPSDLPSVYADQERIRQVLLNLLDNAIKYTPEGGTI 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 387 CI----RSrSQgsTVYIDVVNSGEPIPQTEREMIFEPFFQgsHQRKGAVKGSGLGLSIARDCIRRMQGEIQLVDDKAQEV 462
Cdd:PRK09303 295 TLsmlhRT-TQ--KVQVSICDTGPGIPEEEQERIFEDRVR--LPRDEGTEGYGIGLSVCRRIVRVHYGQIWVDSEPGQGS 369
|
....*..
gi 554317046 463 CFRISLP 469
Cdd:PRK09303 370 CFHFTLP 376
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
228-455 |
1.89e-09 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 58.94 E-value: 1.89e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 228 ELRSVGQRiiwlsERLAWLESQRHQ------FLRHLSHELKTPLASMREGTELLADQVVGPLTPEQKEVvdILDGSSRnL 301
Cdd:PRK11073 107 EMAPMDNQ-----RRLSQEQLQHAQqvaardLVRGLAHEIKNPLGGLRGAAQLLSKALPDPALTEYTKV--IIEQADR-L 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 302 QKLIEQLLDYNRKLVDSATELEAV--DIAPLVDMvvsahSLPARAKMmHTDVDLEAERCIAEPMLLMSVLDNLYSNAVH- 378
Cdd:PRK11073 179 RNLVDRLLGPQRPGTHVTESIHKVaeRVVQLVSL-----ELPDNVRL-IRDYDPSLPELAHDPDQIEQVLLNIVRNALQa 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 379 YGAESGNICIRSRS------QGS----TVYIDVVNSGEPIPQTEREMIFEPFFQGshqRKGavkGSGLGLSIARDCIRRM 448
Cdd:PRK11073 253 LGPEGGTITLRTRTafqltlHGEryrlAARIDIEDNGPGIPPHLQDTLFYPMVSG---REG---GTGLGLSIARNLIDQH 326
|
....*..
gi 554317046 449 QGEIQLV 455
Cdd:PRK11073 327 SGKIEFT 333
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-468 |
4.45e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 54.56 E-value: 4.45e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 365 LMSVLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDvvNSGEPIPQTEREMIFEPFFQGSHQRKGavkgSGLGLSIARDC 444
Cdd:cd16954 38 LMELLGNLLDNACKWCLEFVEVTARQTDGGLHLIVD--DDGPGVPESQRSKIFQRGQRLDEQRPG----QGLGLAIAKEI 111
|
90 100
....*....|....*....|....
gi 554317046 445 IRRMQGEIQLVDDKAQEVCFRISL 468
Cdd:cd16954 112 VEQYGGELSLSDSPLGGARFEVVF 135
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
259-442 |
7.49e-09 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 57.74 E-value: 7.49e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 259 HELKTPLASMREGTE---LLADQVVGpltpEQKEVVDILDGSSRnLQKLIEQLLDYNR-KLVDSATELEAVDIAPLVDMV 334
Cdd:PRK10337 246 HELRSPLAALKVQTEvaqLSDDDPQA----RKKALLQLHAGIDR-ATRLVDQLLTLSRlDSLDNLQDVAEIPLEDLLQSA 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 335 VSAHSLPARAKMMHTDVDLEAERCI--AEPMLLMSVLDNLYSNAVHYGAESGNICIRSRSQGSTvyidVVNSGEPIPQTE 412
Cdd:PRK10337 321 VMDIYHTAQQAGIDVRLTLNAHPVIrtGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLNARNFT----VRDNGPGVTPEA 396
|
170 180 190
....*....|....*....|....*....|
gi 554317046 413 REMIFEPFFQGSHQRKgavKGSGLGLSIAR 442
Cdd:PRK10337 397 LARIGERFYRPPGQEA---TGSGLGLSIVR 423
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
259-471 |
1.55e-08 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 56.66 E-value: 1.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 259 HELKTPLASMREGTELLadqvvgPLTPE-QKEVVDI-LDGSSRnLQKLIEQLLDYNRklvDSATELEAVDIAPLVDMVVS 336
Cdd:COG5805 296 HEIRNPLTSIKGFLQLL------QPGIEdKEEYFDImLSELDR-IESIISEFLALAK---PQAVNKEKENINELIQDVVT 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 337 AhsLPARAKM----MHTDVDLEAERCIAEPMLLMSVLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTE 412
Cdd:COG5805 366 L--LETEAILhniqIRLELLDEDPFIYCDENQIKQVFINLIKNAIEAMPNGGTITIHTEEEDNSVIIRVIDEGIGIPEER 443
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 554317046 413 REMIFEPFFQGSHqrkgavKGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLPLP 471
Cdd:COG5805 444 LKKLGEPFFTTKE------KGTGLGLMVSYKIIENHNGTIDIDSKVGKGTTFTITLPLS 496
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-469 |
2.41e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 51.80 E-value: 2.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 365 LMSVLDNLYSNAVHYGA-ESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFqgSHQRKGAVKG--SGLGLSIA 441
Cdd:cd16953 1 LGQVLRNLIGNAISFSPpDTGRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFY--TERPANEAFGqhSGLGLSIS 78
|
90 100 110
....*....|....*....|....*....|..
gi 554317046 442 RDCIRRMQG----EIQLVDDKAQEVCFRISLP 469
Cdd:cd16953 79 RQIIEAHGGisvaENHNQPGQVIGARFTVQLP 110
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
368-469 |
2.71e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 51.63 E-value: 2.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 368 VLDNLYSNAV----HYGAESGNICIR-SRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGShqrkgaVKGSGLGLSIAR 442
Cdd:cd16920 4 VLINLVRNGIeamsEGGCERRELTIRtSPADDRAVTISVKDTGPGIAEEVAGQLFDPFYTTK------SEGLGMGLSICR 77
|
90 100
....*....|....*....|....*..
gi 554317046 443 DCIRRMQGEIQLVDDKAQEVCFRISLP 469
Cdd:cd16920 78 SIIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
368-469 |
3.74e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 51.52 E-value: 3.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 368 VLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKgAVKGSGLGLSIARDCIRR 447
Cdd:cd16948 9 IIGQIVSNALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGRN-FQESTGMGLYLVKKLCDK 87
|
90 100
....*....|....*....|...
gi 554317046 448 MQGEIqLVDDKAQEVC-FRISLP 469
Cdd:cd16948 88 LGHKI-DVESEVGEGTtFTITFP 109
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-468 |
5.30e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 50.53 E-value: 5.30e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 365 LMSVLDNLYSNA---VHyGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQgshqRKGAVKGSGLGLSIA 441
Cdd:cd16976 1 IQQVLMNLLQNAldaMG-KVENPRIRIAARRLGGRLVLVVRDNGPGIAEEHLSRVFDPFFT----TKPVGKGTGLGLSIS 75
|
90 100
....*....|....*....|....*..
gi 554317046 442 RDCIRRMQGEIQLVDDKAQEVCFRISL 468
Cdd:cd16976 76 YGIVEEHGGRLSVANEEGAGARFTFDL 102
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
364-466 |
1.36e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 49.77 E-value: 1.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 364 LLMSVLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKGAvKGSGLGLSIARD 443
Cdd:cd16975 4 LLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRSG-GHYGMGLYIAKN 82
|
90 100
....*....|....*....|...
gi 554317046 444 CIRRMQGEIQLVDDKAQEVCFRI 466
Cdd:cd16975 83 LVEKHGGSLIIENSQKGGAEVTV 105
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
104-454 |
1.58e-07 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 53.92 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 104 VLPDDKLYQALRQDLNALAQLQckdsGPEAAAAARLEAFANANTEMVQATRTVVysrgQQLQQEIAERGQFFGWQALVLF 183
Cdd:COG4192 261 GSGEGGLPSLRRDELAAQATLE----ALAEENNSILEQLRTQISGLVGNSREQL----VALNQETAQLVQQSGILLLAIA 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 184 LVSLAMVLLFT-----RMIIG---------------------PVKG---IERMINRLGEGRSLGNTVTftgpRELRS-VG 233
Cdd:COG4192 333 LLSLLLAVLINyfyvrRRLVKrlnalsdamaaiaagdldvpiPVDGndeIGRIARLLRVFRDQAIEKT----QELETeIE 408
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 234 QRIIWLSERLAWLESQRH--------QFLRHLSHELKTPLASMREGTELLADQVVGPLTPEQKEVVDILDGSSRNLQKLI 305
Cdd:COG4192 409 ERKRIEKNLRQTQDELIQaakmavvgQTMTSLAHELNQPLNAMSMYLFSAKKALEQENYAQLPTSLDKIEGLIERMDKII 488
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 306 EQLLDYNRKlvdSATELEAVDiapLVDMVVSAHSLPA-RAKMMHTDVDLEAE-RCIAEPMLLMSVLDNLYSNAVHYGAES 383
Cdd:COG4192 489 KSLRQFSRK---SDTPLQPVD---LRQVIEQAWELVEsRAKPQQITLHIPDDlMVQGDQVLLEQVLVNLLVNALDAVATQ 562
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 554317046 384 GNICIRSRSQGSTVYIDVVNSGEPIPQTERemIFEPFFQGSHQrkgavkGSGLGLSIARDCIRRMQGEIQL 454
Cdd:COG4192 563 PQISVDLLSNAENLRVAISDNGNGWPLVDK--LFTPFTTTKEV------GLGLGLSICRSIMQQFGGDLYL 625
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
368-469 |
3.59e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 48.69 E-value: 3.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 368 VLDNLYSNAVHY--GAESGNICIRSRS---QGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHqrkgavKGSGLGLSIAR 442
Cdd:cd16944 8 VLTNILKNAAEAieGRPSDVGEVRIRVeadQDGRIVLIVCDNGKGFPREMRHRATEPYVTTRP------KGTGLGLAIVK 81
|
90 100
....*....|....*....|....*..
gi 554317046 443 DCIRRMQGEIQLVDDKAQEVCFRISLP 469
Cdd:cd16944 82 KIMEEHGGRISLSNREAGGACIRIILP 108
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-454 |
7.78e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 47.58 E-value: 7.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 365 LMSVLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKGAVKGSGLGLSIARDC 444
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDIERCRNTGGTGLGLAIVKHV 80
|
90
....*....|
gi 554317046 445 IRRMQGEIQL 454
Cdd:cd16952 81 MSRHDARLLI 90
|
|
| nifL_nitrog |
TIGR02938 |
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation ... |
363-471 |
1.41e-06 |
|
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation positive regulator protein NifA, and is therefore a negative regulator. It binds NifA. NifA and NifL are encoded by adjacent genes. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, Protein interactions]
Pssm-ID: 131984 [Multi-domain] Cd Length: 494 Bit Score: 50.67 E-value: 1.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 363 MLLMSVLDNLYSNAVHYGAESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEPFF--QGSHQrkgavKGSGLGLSI 440
Cdd:TIGR02938 390 SLFKALVDNAIEAMNIKGWKRRELSITTALNGDLIVVSILDSGPGIPQDLRYKVFEPFFttKGGSR-----KHIGMGLSV 464
|
90 100 110
....*....|....*....|....*....|.
gi 554317046 441 ARDCIRRMQGEIQlVDDKAQEVCfRISLPLP 471
Cdd:TIGR02938 465 AQEIVADHGGIID-LDDDYSEGC-RIIVEFR 493
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
250-476 |
1.43e-06 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 51.09 E-value: 1.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 250 RHQFLRHLSHELKTPLASMREgtelLADQVVGPLTPEQkevvdildgSSRNLQKLIEQlLDYNRKLVDS---ATELEAVD 326
Cdd:PRK10618 450 RKAFLQNIGDELKQPLQSLAQ----LAAQLRQTSDEEQ---------QQPELDQLAEQ-SDVLVRLVDNiqlLNMLETQD 515
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 327 IAP---------LVDMVVSAhSLPA-RAK----MMHTDVDLEAERcIAEPMLLMSVLDNLYSNAV---HYGAESGNICiR 389
Cdd:PRK10618 516 WKPeqelfslqdLIDEVLPE-VLPAiKRKglqlLIHNHLKAEQLR-IGDRDALRKILLLLLNYAItttAYGKITLEVD-Q 592
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 390 SRSQGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKGAvKGSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLP 469
Cdd:PRK10618 593 DESSPDRLTIRILDTGAGVSIKELDNLHFPFLNQTQGDRYG-KASGLTFFLCNQLCRKLGGHLTIKSREGLGTRYSIHLK 671
|
....*..
gi 554317046 470 LPASDKH 476
Cdd:PRK10618 672 MLAADPE 678
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-469 |
1.64e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 46.51 E-value: 1.64e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 365 LMSVLDNLYSNAVHYGAESGN----ICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEpffQGSHQRkgAVKGSGLGLSI 440
Cdd:cd16915 1 LITIVGNLIDNALDALAATGApnkqVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFE---RGVSTK--GQGERGIGLAL 75
|
90 100
....*....|....*....|....*....
gi 554317046 441 ARDCIRRMQGEIQLVDDKAQEVCFRISLP 469
Cdd:cd16915 76 VRQSVERLGGSITVESEPGGGTTFSIRIP 104
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
361-454 |
2.21e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 46.25 E-value: 2.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 361 EPMLLMSVLDNLYSNAVHYGAESGNICIRSRSQGSTVYIdVVNSGEPIPQTEREMIFEPFFQGSHQrkgAVKGSGLGLSI 440
Cdd:cd16940 10 DALLLFLLLRNLVDNAVRYSPQGSRVEIKLSADDGAVIR-VEDNGPGIDEEELEALFERFYRSDGQ---NYGGSGLGLSI 85
|
90
....*....|....
gi 554317046 441 ARDCIRRMQGEIQL 454
Cdd:cd16940 86 VKRIVELHGGQIFL 99
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
368-469 |
3.18e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 46.22 E-value: 3.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 368 VLDNLYSNAVHYGAESGNICIRSRSQ---------------GSTVYIDVVNSGEPIPQTEREMIFEPFFQgshqRKGAVK 432
Cdd:cd16919 4 AILNLAVNARDAMPEGGRLTIETSNQrvdadyalnyrdlipGNYVCLEVSDTGSGMPAEVLRRAFEPFFT----TKEVGK 79
|
90 100 110
....*....|....*....|....*....|....*..
gi 554317046 433 GSGLGLSIARDCIRRMQGEIQLVDDKAQEVCFRISLP 469
Cdd:cd16919 80 GTGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
365-469 |
5.80e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 45.01 E-value: 5.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 365 LMSVLDNLYSNAVHYG--AESGNICIRSRSQGSTVYIDVVNSGEPIPQTEREMIFEpFFQGSHQRkGAVKGSGLGLSIAR 442
Cdd:cd16921 1 LGQVLTNLLGNAIKFRrpRRPPRIEVGAEDVGEEWTFYVRDNGIGIDPEYAEKVFG-IFQRLHSR-EEYEGTGVGLAIVR 78
|
90 100
....*....|....*....|....*..
gi 554317046 443 DCIRRMQGEIQLVDDKAQEVCFRISLP 469
Cdd:cd16921 79 KIIERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
313-472 |
8.44e-04 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 41.81 E-value: 8.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 313 RKLVDSaTELEAVDIAPLVDMVVSAHSLPARAKMMHTDVDLEAERC---IAEPMLLmsVLDNLYSNAVHYGA---ESGNI 386
Cdd:COG3920 348 ELLYQS-EDWEGVDLRDYLRELLEPLRDSYGGRGIRIELDGPDVELpadAAVPLGL--ILNELVTNALKHAFlsgEGGRI 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 387 CIRSRSQGSTVYIDVVNSGEPIPQTeremiFEPffqgshqrkgaVKGSGLGLSIARDCIRRMQGEIQLvdDKAQEVCFRI 466
Cdd:COG3920 425 RVSWRREDGRLRLTVSDNGVGLPED-----VDP-----------PARKGLGLRLIRALVRQLGGTLEL--DRPEGTRVRI 486
|
....*.
gi 554317046 467 SLPLPA 472
Cdd:COG3920 487 TFPLAE 492
|
|
| PRK13559 |
PRK13559 |
hypothetical protein; Provisional |
246-417 |
1.87e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237427 [Multi-domain] Cd Length: 361 Bit Score: 40.57 E-value: 1.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 246 LESQRHQFLRHLSHELKTPLAsmregtelLADQVVGpLTPEQKEVVDILDGSSRNLQKLI---EQLLDynrklvdsATEL 322
Cdd:PRK13559 166 LEAHERRLAREVDHRSKNVFA--------VVDSIVR-LTGRADDPSLYAAAIQERVQALArahETLLD--------ERGW 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 554317046 323 EAVDIAPLVDMVVSAHSLPA-RAKMMHTDVDLEAErcIAEPMLLmsVLDNLYSNAVHYGA---ESGNICI--RSRSQGST 396
Cdd:PRK13559 229 ETVEVEELIRAQVAPYAPRAtRVAFEGPGIRLGAA--SVQPLGL--VLHELAVNAIKHGAlsaDQGRISIswKPSPEGAG 304
|
170 180
....*....|....*....|.
gi 554317046 397 VYIDVVNSGEPIPQTEREMIF 417
Cdd:PRK13559 305 FRIDWQEQGGPTPPKLAKRGF 325
|
|
| |
