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Conserved domains on  [gi|485354137|gb|EOC15450|]
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hypothetical protein NM73696_0117 [Neisseria meningitidis 73696]

Protein Classification

cyanase( domain architecture ID 1904182)

cyanase catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide, and is used to decompose cyanate for use as the sole source of nitrogen

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cyanase_C super family cl42212
Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of ...
 21-64 3.36e-07

Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of cyanate. It catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. This allows organisms that possess the enzyme to overcome the toxicity of environmental cyanate and to use cyanate as a source of nitrogen for growth. This enzyme is a homodecamer, formed by five dimers. Each monomer is composed of two domains, an N-terminal helix-turn-helix and this structurally unique C-terminal domain.


The actual alignment was detected with superfamily member PRK02866:

Pssm-ID: 455557 [Multi-domain]  Cd Length: 147  Bit Score: 44.04  E-value: 3.36e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 485354137  21 EAKVEK---WRQLGAEHGLSGEWAVAARLGENGFTEEQMENIANLFG 64
Cdd:PRK02866  12 AAKKEKgltWADIAEAIGLSEVWVTAALLGQMTLPAEEAEKVAELLG 58
 
Name Accession Description Interval E-value
PRK02866 PRK02866
cyanate hydratase; Validated
 21-64 3.36e-07

cyanate hydratase; Validated


Pssm-ID: 235079 [Multi-domain]  Cd Length: 147  Bit Score: 44.04  E-value: 3.36e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 485354137  21 EAKVEK---WRQLGAEHGLSGEWAVAARLGENGFTEEQMENIANLFG 64
Cdd:PRK02866  12 AAKKEKgltWADIAEAIGLSEVWVTAALLGQMTLPAEEAEKVAELLG 58
 
Name Accession Description Interval E-value
PRK02866 PRK02866
cyanate hydratase; Validated
 21-64 3.36e-07

cyanate hydratase; Validated


Pssm-ID: 235079 [Multi-domain]  Cd Length: 147  Bit Score: 44.04  E-value: 3.36e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 485354137  21 EAKVEK---WRQLGAEHGLSGEWAVAARLGENGFTEEQMENIANLFG 64
Cdd:PRK02866  12 AAKKEKgltWADIAEAIGLSEVWVTAALLGQMTLPAEEAEKVAELLG 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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